Regulation of zygotic gene activation in the preimplantation mouse embryo: Global activation and repression of gene expression

Biology of Reproduction

Volumn 64, Issue 6, 2001, Pages 1713-1721

  Ma, J ^a   Svoboda, P ^a   Schultz, R M ^a   Stein, P ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Developmental biology; Early development; Embryo; Gene regulation

Indexed keywords

APHIDICOLIN; DNA POLYMERASE; HISTONE; HISTONE DEACETYLASE INHIBITOR; MESSENGER RNA; TRICHOSTATIN A;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIVISION; CHROMATIN STRUCTURE; DNA REPLICATION; EMBRYO; EMBRYO DEVELOPMENT; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENE SEQUENCE; GENOME; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

EID: 0035013086     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod64.6.1713     Document Type: Article

References (35)

1. Regulation of zygotic gene activation in the mouse
2. The regulation and reprogramming of gene expression in the preimplantation embryo
3. Amounts and modulation of actin mRNAs in mouse oocytes and embryos
4. TATA-dependent enhancer stimulation of promoter activity in mice is developmentally acquired
5. Developmental change in TATA-box utilization during preimplantation mouse development
6. Transient expression of translation initiation factor eIF-4C during the 2-cell stage of the preimplantation mouse embryo: Identification by mRNA differential display and the role of DNA replication
7. Role of the first round of DNA replication in reprogramming gene expression in the preimplantation mouse embryo
8. The need for enhancers is acquired upon formation of a diploid nucleus during early mouse development
9. The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus
10. Regulation of gene expression in preimplantation mouse embryos: Effects of the zygotic clock and the first mitosis on promoter and enhancer activities
11. Repression of gene expression at the beginning of mouse development
12. Sequential acquisition of transcriptional control during early embryonic development in the rabbit
13. Analysis of gene expression in mouse preimplantation embryos demonstrates that the primary role of enhancers is to relieve repression of promoters
14. A unique role for enhancers is revealed during early mouse development
15. Regulation of gene expression at the beginning of mammalian development
16. Histone acetylation in chromatin and chromosomes
17. Chromatin disruption and modification
18. Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei
19. Regulation of transcriptional activity during the first and second cell cycles in the preimplantation mouse embryo
20. Regulation of mouse oocyte maturation: Implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis
21. Preimplantation development of mouse embryos in KSOM: Augmentation by amino acids and analysis of gene expression
22. Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase
23. Analysis of gene expression in the preimplantation mouse embryo: Use of mRNA differential display
24. Expression patterns of novel genes during mouse preimplantation embryogenesis
25. Temporally restricted spatial localization of acetylated isoforms of histone H4 and RNA polymerase II in the 2-cell mouse embryo
26. DNA replication in the 1-cell mouse embryo: Stimulatory effect of histone acetylation
27. Changes in histone synthesis and modification at the beginning of mouse development correlate with the establishment of chromatin mediated repression of transcription
28. Initiation of a chromatin-based transcriptionally repressive state in the preimplantation mouse embryo: Lack of a primary role for expression of somatic histone H1
29. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development
30. Quantitative analysis of protein synthesis in mouse embryos. I. Extensive reprogramming at the one- and two-cell stages
31. Differential H4 acetylation of paternal and maternal chromatin precedes DNA replication and differential transcriptional activity in pronuclei of 1-cell mouse embryos
32. Linker histone transitions during mammalian oogenesis and embryogenesis
33. Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I
34. Trichostatin A and trapoxin: Novel chemical probes for the role of histone acetylation in chromatin structure and function
35. Histone acetylation influences both gene expression and development of Xenopus laevis