Leptin promotes the development of mouse preimplantation embryos in vitro

Endocrinology

Volumn 143, Issue 5, 2002, Pages 1922-1931

  Kawamura, Kazuhiro ^a   Sato, Naoki ^a   Fukuda, Jun ^a   Kodama, Hideya ^a   Kumagai, Jin ^a   Tanikawa, Hideo ^a   Nakamura, Akira ^a   Tanaka, Toshinobu ^a  

^a AKITA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; NEUTRALIZING ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BLASTOCYST; CELL COUNT; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOMETRIUM; FEMALE; HORMONAL REGULATION; IN VITRO STUDY; MOUSE; NONHUMAN; PARACRINE SIGNALING; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; REPRODUCTION; UTERINE TUBE MUCOSA; UTERUS FLUID;

EID: 0036225416     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.143.5.8818     Document Type: Article

References (59)

1. Positional cloning of the mouse obese gene and its human homologue
2. Leptin: The tale of an obese gene
3. Effects of the obese gene product on body weight regulation in ob/ob mice
4. Weight-reducing effects of the plasma protein encoded by the obese gene
5. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
6. Current concepts concerning the role of leptin in reproductive function
7. Leptin and reproduction
8. Hypothalamic and genetic obesity in experimental animals: An autonomic and endocrine hypothesis
9. Leptin treatment rescues the sterility of genetically obese ob/ob males
10. Leptin is a metabolic signal to the reproductive system
11. The in vivo and in vitro effects of exogenous leptin on ovulation in the rat
12. Plasma leptin levels in healthy children and adolescents: Dependence on body mass index, body fat mass, gender, pubertal age, and testosterone
13. Serum leptin levels in normal children: Relationship to age, gender, body mass index, pituitary-gonadal hormones, and pubertal age
14. A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. V. Rising leptin levels may signal the onset of puberty
15. The impact of reversible gonadal sex steroid suppression on serum leptin concentrations in children with central precocious puberty
16. Leptin accelerates the onset of puberty in normal female mice
17. Early oncet of reproductive function in normal female mice treated with leptin
18. Circulating leptin in women: A longitudinal study in the menstrual cycle and during pregnancy
19. Serum leptin concentration increase during luteal phase in healthy premenopausal women
20. Adiposity, plasma leptin concentration and reproductive function in active and sedentary females
21. Serum immunoreactive leptin concentrations in women with polycystic ovary syndrome
22. Leptin: A hormone of reproduction
23. Identification and expression cloning of a leptin receptor, OB-R
24. Abnormal splicing of the leptin receptor in diabetic mice
25. Defective STAT signaling by the leptin receptor in diabetic mice
26. The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
27. Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
28. Divergent signaling capacities of the long and short isoforms of the leptin receptor
29. Leptin in pregnancy
30. In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: Overlapping but distinct pathways from insulin
31. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
32. Human leptin stimulates proliferation and activation of human circulating monocytes
33. Human leptin enhances activation and proliferation of human circulating T lymphocytes
34. Rat insulinoma-derived pancreatic β-cells express a functional leptin receptor that mediates a proliferative response
35. Leptin induces proliferation of pancreatic β cell line MIN6 through activation of mitogen-activated protein kinase
36. Biological action of leptin as an angiogenic factor
37. A role for leptin in brain development
38. Expression of leptin receptor in lung: Leptin as a growth factor
39. Human blood-brain barrier leptin receptor: Binding and endocytosis in isolated human brain microvesseles
40. Expression of leptin receptor isoforms in rat brain microvesseles
41. Modulation of circulating leptin levels by its soluble receptor
42. The expression of leptin and its receptors in pre-ovulatory human follicles
43. Oocyte influences on early development: The regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation satge embryo
44. Tyrosine phosphorylation of STAT3 by leptin through leptin receptor in mouse metaphase 2 stage oocyte
45. Chaperonin 10 in the rat oocytes and early embryos: Its expression and activity for early pregnancy factor
46. Expression of Fas and Fas ligand mRNA in rat and human preimplantation embryos
47. Improved pregnancy rate in human in vitro fertilization with the use of a medium on the composition of human tubal fluid
48. A rapid procedure for visualising the inner cell mass and trophectoderm nuclei of mouse blastocysts in situ using polynucleotide-specific fluorochromes
49. The transition from maternal to embryonic control in the 2-cell mouse embryo
50. Leptin and leptin receptor are expressed in the human endometrium and endometrial leptin secretion is regulated by the human blastocyst
51. Activities of growth factors in preimplantation embryos
52. Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H10T1/2 cells
53. Leptin stimulates fetal and adult erythroid and myeloid development
54. Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells
55. Leukemia inhibitory factor significantly enhances the blastocyst formation rates of human embryos cultured in serum-free medium
56. Relationship between timing of development, morula morphology and cell allocation to inner cell mass and trophectoderm in in-vitro produced bovine embryos