Yeast cell factories for fine chemical and API production

Microbial Cell Factories

Volumn 7, Issue , 2008, Pages

  Pscheidt, Beate ^a   Glieder, Anton ^a,b  

^a RESEARCH CENTRE APPLIED BIOCATALYSIS   (Austria)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BUTANEDIOL; 2 AMINO 5 (1,3 DIOXOLAN 2 YL) PENTANOIC ACID; 2 HYDROXY CYCLOPENTANE CARBONITRILE; 3 HYDROXYACYL COENZYME A DEHYDROGENASE; 5 HYDROXYHEXANENITRILE; AMINOALCOHOL; ASTAXANTHIN; BETA CAROTENE; BETA HYDROXY ISOBUTYRIC ACID; BETA HYDROXY N BUTYRIC ACID; CHIRAL BETA HYDROXY ESTER; CORTODOXONE; EPHEDRINE; ETHYL 5 HYDROXYHEXANOATE; FUNGAL ENZYME; HEXAHOMOSERINE; HYDROCORTISONE; LYCOPENE; LYSINE; NATURAL PRODUCT; PHENETHYL ALCOHOL; PHENYLALANINE; PREGNENOLONE; PROGESTERONE; PSEUDOEPHEDRINE; STYRENE OXIDE; TALAMPANEL; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZEAXANTHIN;

BIOCATALYST; BIOTRANSFORMATION; CANDIDA; CHEMICAL BOND; CHEMICAL REACTION; CRYPTOCOCCUS; DISULFIDE BOND; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME CONFORMATION; ENZYME MECHANISM; FUNGAL STRAIN; GENE OVEREXPRESSION; GENE SILENCING; GEOTRICHUM; ISSATCHENKIA; KLOECKERA; KLUYVEROMYCES; NONHUMAN; OXIDATION; PICHIA; RACEMIZATION; REVIEW; RHODOSPORIDIUM; RHODOTORULA; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; SCREENING TEST; STRUCTURE ANALYSIS; TORULOPSIS; TRICHOSPORON; TRIGONOPSIS VARIABILIS; YARROWIA LIPOLYTICA; ZYGOSACCHAROMYCES ROUXII;

CANDIDA; CRYPTOCOCCUS SP.; GEOTRICHUM; ISSATCHENKIA; KLOECKERA; KLUYVEROMYCES; PICHIA ANGUSTA; PICHIA SP.; RHODOSPORIDIUM; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES SP.; SCHIZOSACCHAROMYCES POMBE; TORULOPSIS; TRIGONOPSIS VARIABILIS; YARROWIA LIPOLYTICA; ZYGOSACCHAROMYCES ROUXII;

EID: 59049091116     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-7-25     Document Type: Review

References (245)

1. Delwen S Ancient Egyptian Cereal Processing: Beyond the Artistic Record Cambridge Archaeological Journal 1993, 276-283
2. Delwen S Investigation of Ancient Egyptian Baking and Brewing Methods by Correlative Microscopy Science 1996, 273:488-490 8662535
3. Ray J The Oxford Encyclopedia of Ancient Egypt Tls-the Times Literary Supplement 2001, 6
4. Barnett JA Beginnings of microbiology and biochemistry: The contribution of yeast research Microbiology-Sgm 2003, 149:557-567
5. Fischer E Thierfelder H Verhalten der verschiedenen Zucker gegen reine Hefen Ber Dtsch Chem Ges 1894, 27:2031-2037
6. Henri V Lois Général de l'Action des Diastases Paris: Hermann 1903
7. Michaelis L Menten ML Die Kinetik der Invertasewirkung Biochem Z 1913, 49:333-369
8. Haldane JBS Enzymes London: Longmans, Green 1930
9. Koshland DE Application of A Theory of Enzyme Specificity to Protein Synthesis Proceedings of the National Academy of Sciences of the United States of America 1958, 44:98-104 335371 16590179
10. Koshland DE The Key-Lock Theory and the Induced Fit Theory Angewandte Chemie-International Edition 1995, 33:2375-2378
11. Monod J The phenomenon of enzymatic adaptation and its bearing on problems of genetics and cellular differentiation Growth 1947, 11:223-289
12. Forsburg SL Nurse P Cell-Cycle Regulation in the Yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe Annual Review of Cell Biology 1991, 7:227-256 1809348
13. Hartwell LH 25 Years of Cell-Cycle Genetics Genetics 1991, 129:975-980 1204781 1783298
14. Kurtzman CP Molecular Taxonomy of the Yeasts Yeast 1994, 10:1727-1740 7747515
15. Boekhout T Kurtzman CP Principles and methods used in yeast classification, and an overview of currently accepted yeast genera Nonconventional Yeasts in biotechnology. A Handbook Berlin, Heidelberg: Springer-Verlag Wolf K 1996, 1-99
16. Hibbett DS Binder M Bischoff JF Blackwell M Cannon PF Eriksson OE Huhndorf S James T Kirk PM Lucking R et al A higher-level phylogenetic classification of the Fungi Mycological Research 2007, 111:509-547 17572334
17. Barnett JA A history of research on yeasts 8: Taxonomy Yeast 2004, 21:1141-1193 15515119
18. Walker GM Introduction to Yeasts Yeast Physiology and Biotechnology Chichester: John Wiley & Sons Ltd 1998, 1-9
19. The Yeasts - A Taxonomic Study: Fourth Revised and Enlarged Edition Amsterdam: Elsevier 1997
20. Scannell DR Butler G Wolfe KH Yeast genome evolution - the origin of the species Yeast 2007, 24:929-942 17621376
21. Neuberg C Hirsch J Reinfurth E The three fermentation-forms of sugar, their coherences and balance Biochemische Zeitschrift 1920, 105:307-336
22. Neuberg C Hirsch J The carbon chain of attached enzymes (carboligase) Biochemische Zeitschrift 1921, 115:282-310
23. Neubauer O Fromherz K The decomposition of amino acids in yeast fermentation Hoppe-Seylers Zeitschrift fur Physiologische Chemie 1911, 70:326-350
24. Faber K Biotransformations in Organic Chemistry - A Textbook Berlin, Heidelberg: Springer-Verlag 2004
25. Yamada H Shimizu S Microbial and Enzymatic Processes for the Production of Biologically and Chemically Useful Compounds Angewandte Chemie-International Edition in English 1988 ,27:622-642
26. Fujio T Minimum genome factory: Innovation in bioprocesses through genome science Biotechnology and Applied Biochemistry 2007, 46:145-146
27. Mizoguchi H Mori H Fujio T Escherichia coli minimum genome factory Biotechnology and Applied Biochemistry 2007, 46:157-167
28. Ara K Ozaki K Nakamura K Yamane K Sekiguchi J Ogasawara N Bacillus minimum genome factory: Effective utilization of microbial genome information Biotechnology and Applied Biochemistry 2007, 46:169-178
29. Giga-Hama Y Tohda H Takegawa K Kumagai H Schizosoccharomyces pombe minimum genome factory Biotechnology and Applied Biochemistry 2007, 46:147-155
30. Servi S Baker's yeast as a reagent in organic synthesis Synthesis-Stuttgart 1990, 1-25
31. Windisch W Wochenschrift für Brauerei 1898, 15-189
32. Lintner CJ von Liebig HJ The reduction of furfural through yeast in alcoholic fermentation Hoppe-Seylers Zeitschrift fur Physiologische Chemie 1911, 72:449-454
33. Neuberg C Biochemical Reductions at the Expense of Sugars Advances in Carbohydrate Chemistry 1949, 4:75-117
34. Csuk R Glanzer BI Bakers Yeast Mediated Transformations in Organic Chemistry Chemical Reviews 1991, 91:49-97
35. Kometani T Yoshii H Matsuno R Large-scale production of chiral alcohols with baker's yeast Journal of Molecular Catalysis B: Enzymatic 1996, 1:45-52
36. Nakamura K Yamanaka R Matsuda T Harada T Recent developments in asymmetric reduction of ketones with biocatalysts Tetrahedron-Asymmetry 2003, 14:2659-2681
37. Goldberg K Schroer K Lutz S Liese A Biocatalytic ketone reduction - a powerful tool for the production of chiral alcohols - part II: whole-cell reductions Applied Microbiology and Biotechnology 2007, 76:249-255
38. Stewart JD Dehydrogenases and transaminases in asymmetric synthesis Current Opinion in Chemical Biology 2001, 5:120-129 11282337
39. Mueller M Wolberg M Schubert T Hummel W Enzyme catalyzed regio- and enantioselective ketone reductions Advances in Biochemical Engineering/ Biotechnology 2005, 92;261-287 15791940
40. Kula M-R Kragl U Dehydrogenases in the synthesis of chiral compounds Stereoselective Biocatalysis New York: Marcel Dekker Patel RN 2000, 839-866
41. Nakamura K Matsuda T Harada T Chiral synthesis of secondary alcohols using Geotrichum candidum Chirality 2002, 14:703-708 12237828
42. Nakamura K Matsuda T Reduction of ketones Enzyme Catalysis in Organic Synthesis Weinheim: Wiley-VCH Drauz K, Waldmann H 2002, 3:991-1047
43. Patel RN Biocatalytic synthesis of intermediates for the synthesis of chiral drug substances Current Opinion in Biotechnology 2001, 12:587-604 11849941
44. Prelog V Specification of the stereospecificity of some oxidoreductases by diamond lattice sections Pure and Applied Chemistry 1964, 9:119-130
45. Macleod R Prosser H Fikentscher L Mosher HS Lanyi J Asymmetric Reductions 12. Stereoselective Ketone Reductions by Fermenting Yeast Biochemistry 1964, 3:838 14211626
46. Chen CS Zhou BN Girdaukas G Shieh WR Vanmiddlesworth F Gopalan AS Sih CJ Stereochemical Control of Yeast Reductions. 2. Quantitative Treatment of the Kinetics of Competing Enzyme-Systems for A Single Substrate Bioorganic Chemistry 1984, 12:98-117
47. Rodriguez S Kayser M Stewart JD Improving the stereoselectivity of baker's yeast reductions by genetic engineering Organic Letters 1999, 1:1153-1155 10825967
48. Mewes HW Albermann K Bahr M Frishman D Gleissner A Hani J Heumann K Kleine K Maierl A Oliver SG et al Overview of the yeast genome Nature 1997, 387:7-8 9169865
49. Goffeau A Barrell BG Bussey H Davis RW Dujon B Feldmann H Galibert F Hoheisel JD Jacq C Johnston M et al Life with 6000 genes Science 1996, 274:546 8849441
50. Zhou BN Gopalan AS Vanmiddlesworth F Shieh WR Sih CJ Stereochemical Control of Yeast Reductions. 1. Asymmetric Synthesis of L-Carnitine Journal of the American Chemical Society 1983, 105:5925-5926
51. Ehrler J Giovannini F Lamatsch B Seebach D Stereoselectivity of Yeast Reductions - An Improved Procedure for the Preparation of Ethyl (S)-3-Hydroxybutanoate and (S)-2-Hydroxymethylbutanoate Chimia 1986, 40:172-173
52. Nakamura K Kawai Y Ohno A Stereochemical Control in Microbial Reduction 13. A Novel Method to Synthesize (L)-Beta-Hydroxyl Esters by the Reduction with Baker's Yeast Tetrahedron Letters 1990, 31:267-270
53. Jayasinghe LY Smallridge AJ Trewhella MA The Yeast Mediated Reduction of Ethyl Acetoacetate in Petroleum Ether Tetrahedron Letters 1993, 34:3949-3950
54. DArrigo P Fantoni GP Servi S Strini A The effect of absorbing resins on substrate concentration and enantiomeric excess in yeast reduction Tetrahedron-Asymmetry 1997, 8:2375-2379
55. Pfruender H Jones R Weuster-Botz D Water immiscible ionic liquids as solvents for whole cell biocatalysis Journal of Biotechnology 2006, 124:182-190 16413078
56. Lagos FM Del Campo C Llama EF Sinisterra JV New yeast strains for enantioselective production of halohydrin precursor of (S)-propranolol Enzyme and Microbial Technology 2002, 30:895-901
57. Dehli JR Gotor V Dynamic kinetic resolution of 2-oxocycloalkanecarbonitriles: Chemoenzymatic syntheses of optically active cyclic beta- and gamma-amino alcohols Journal of Organic Chemistry 2002, 67:6816-6819 12227816
58. Enders D Vicario JL Job A Wolberg M Muller M Asymmetric total synthesis of (-)-callystatin A and (-)-20-epi-callystatin A employing chemical and biological methods Chemistry-A European Journal 2002, 8:4272-4284
59. Bertau M Burli M Enantioselective microbial reduction with baker's yeast on an industrial scale Chimia 2000, 54:503-507
60. Barbieri C Caruso E D'Arrigo P Fantoni GP Servi S Chemo-enzymatic synthesis of (R)- and (S)-3,4-dichlorophenylbutanolide intermediate in the synthesis of sertraline Tetrahedron-Asymmetry 1999, 10:3931-3937
61. Matsuyama A Yamamoto H Kawada N Kobayashi Y Industrial production of (R)-1,3-butanediol by new biocatalysts Journal of Molecular Catalysis B: Enzymatic 2001, 11:513-521
62. Soni P Banerjee UC Biotransformations for the production of the chiral drug (S)-Duloxetine catalyzed by a novel isolate of Candida tropicalis Applied Microbiology and Biotechnology 2005, 67:771-777
63. Etschmann MMW Schrader J An aqueous-organic two-phase bioprocess for efficient production of the natural aroma chemicals 2-phenylethanol and 2-phenylethylacetate with yeast Applied Microbiology and Biotechnology 2006, 71:440-443
64. Stark D Munch T Sonnleitner B Marison IW von Stockar U Extractive bioconversion of 2-phenylethanol from L-phenylalanine by Saccharomyces cerevisiae Biotechnology Progress 2002, 18:514-523 12052068
65. Kroutil W Mang H Edegger K Faber K Recent advances in the biocatalytic reduction of ketones and oxidation of sec-alcohols Current Opinion in Chemical Biology 2004, 8:120-126 15062771
66. Yasohara Y Kizaki N Hasegawa J Wada M Kataoka M Shimizu S Stereoselective reduction of alkyl 3-oxobutanoate by carbonyl reductase from Candida magnoliae Tetrahedron-Asymmetry 2001, 12:1713-1718
67. Kizaki N Yasohara Y Hasegawa J Wada M Kataoka M Shimizu S Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes Applied Microbiology and Biotechnology 2001, 55:590-595
68. Stewart JD Organic transformations catalyzed by engineered yeast cells and related systems Current Opinion in Biotechnology 2000, 11:363-368 10975455
69. Kataoka M Kita K Wada M Yasohara Y Hasegawa J Shimizu S Novel bioreduction system for the production of chiral alcohols Applied Microbiology and Biotechnology 2003, 62:437-445
70. Warburg O Christian W Yellow enzyme and its effects Biochemische Zeitschrift 1933, 266:377-411
71. Stuermer R Hauer B Hall M Faber K Asymmetric bioreduction of activated C= C bonds using enoate reductases from the old yellow enzyme family Current Opinion in Chemical Biology 2007, 11:203-213 17353140
72. Tischer W Bader J Simon H Purification and some properties of a hitherto-unknown enzyme reducing the carbon-carbon double-bond of alpha,beta-unsaturated carboxylate anions European Journal of Biochemistry 1979, 97:103-112 477658
73. Leuenberger HGW Boguth W Widmer E Zell R Synthesis of Optically Active Natural Carotenoids and Structurally Related Compounds. 1. Synthesis of Chiral Key Compound (4R, 6R)-4-Hydroxy-2,2,6-Trimethylcyclohexanone Helvetica Chimica Acta 1976, 59:1832-1849
74. Liese A Seelbach K Buchholz A Haberland J Processes Industrial Biotransformations Weinheim: Wiley-VCH Liese A, Seelbach K, Wandrey C 2 2006, 147-514
75. Kawai Y Inaba Y Tokitoh N Asymmetric reduction of nitroalkenes with baker's yeast Tetrahedron-Asymmetry 2001, 12:309-318
76. Ohta H Kobayashi N Ozaki K Asymmetric Reduction of Nitro Olefins by Fermenting Baker's Yeast Journal of Organic Chemistry 1989, 54:1802-1804
77. Leuenberger HGW Boguth W Barner R Schmid M Zell R Total Synthesis of Natural Alpha-Tocopherol 1. Preparation of Bifunctional Optically-Active Precursors for the Synthesis of the Side-Chain by Means of Microbiological Transformations Helvetica Chimica Acta 1979, 62:455-463
78. Cantello BCC Eggleston DS Haigh D Haltiwanger RC Heath CM Hindley RM Jennings KR Sime JT Woroniecki SR Facile Biocatalytic Reduction of the Carbon-Carbon Double-Bond of 5-Benzylidenethiazolidine-2,4-Diones - Synthesis of (+/ -)-5-(4-(2-[Methyl(2-Pyridyl)Amino]Ethoxy)Benzyl)Thiazolidine-2,4-Dione (Brl-49653), Its (R)-(+)-Enantiomer and Analogs Journal of the Chemical Society-Perkin Transactions 1 1994, 3319-3324
79. Mori A Ishiyama I Akita H Suzuki K Mitsuoka T Oishi T Reduction of Nitroolefin Using Microorganisms Chemical & Pharmaceutical Bulletin 1990, 38:3449-3451 2092944
80. Wada M Yoshizumi A Noda Y Kataoka M Shimizu S Takagi H Nakamori S Production of a doubly chiral compound, (4R, 6R)-4-hydroxy-2,2,6-trimethylcyclohexanone, by two-step enzymatic asymmetric reduction Applied and Environmental Microbiology 2003, 69:933-937
81. Swiderska MA Stewart JD Stereoselective enone reductions by Saccharomyces carlsbergensis old yellow enzyme Journal of Molecular Catalysis B: Enzymatic 2006, 42:52-54
82. Kataoka M Kotaka A Thiwthong R Wada M Nakamori S Shimizu S Cloning and overexpression of the old yellow enzyme gene of Candida macedoniensis, and its application to the production of a chiral compound Journal of Biotechnology 2004, 114:1-9 15464593
83. Tani Y Ogata K Nishikaw H Miya T Microbial metabolism of methanol 1. Formation and crystallization of methanol-oxidizing enzyme in a methanol-utilizing yeast, Kloeckera sp. No 2201 Agricultural and Biological Chemistry 1972, 3:68
84. Tani Y Miya T Ogata K Microbial metabolism of methanol 2. Properties of crystalline alcohol oxidase from Kloeckera sp. No 2201 Agricultural and Biological Chemistry 1972, 36:76
85. Fujii T Tonomura K Oxidation of Methanol, Formaldehyde and Formate by a Candida Species Agricultural and Biological Chemistry 1972, 36:2297-2306
86. Nestl BM Bodlenner A Stuermer R Hauer B Kroutil W Faber K Biocatalytic racemization of synthetically important functionalized alpha-hydroxyketones using microbial cells Tetrahedron-Asymmetry 2007, 18:1465-1474
87. Walker AJ Asymmetric Carbon-Carbon Bond Formation Using Sulfoxide-Stabilized Carbanions Tetrahedron-Asymmetry 1992, 3:961-998
88. Chen G Kayser MM Mihovilovic MD Mrstik ME Martinez CA Stewart JD Asymmetric oxidations at sulfur catalyzed by engineered strains that overexpress cyclohexanone monooxygenase New Journal of Chemistry 1999, 23:827-832
89. Patel RN Hou CT Laskin AI Derelanko P Felix A Oxidation of Secondary Alcohols to Methyl Ketones by Yeasts Applied and Environmental Microbiology 1979, 38:219-223
90. Beecher J Brackenridge I Roberts SM Tang J Willetts AJ Oxidation of Methyl p-Tolyl Sulfide with Baker's Yeast - Preparation of A Synthon of the Mevinic Acid-Type Hypocholestemic Agents Journal of the Chemical Society-Perkin Transactions 1 1995, 1641-1643
91. Buist PH Marecak DM Partington ET Skala P Enantioselective Sulfoxidation of A Fatty Acid Analog by Baker's Yeast Journal of Organic Chemistry 1990, 55:5667-5669
92. Nestl BM Voss CV Bodlenner A Ellmer-Schaumberger U Kroutil W Faber K Biocatalytic racemization of sec-alcohols and alpha-hydroxyketones using lyophilized microbial cells Applied Microbiology and Biotechnology 2007, 76:1001-1008
93. Titu D Chadha A Preparation of optically pure alkyl 3-(hetero-2-yl)-3-hydroxypropanoates by Candida parapsilosis ATCC 7330 mediated deracemisation Journal of Molecular Catalysis B: Enzymatic 2008, 52-3:168-172
94. Mamoli L The behaviour of estrogen hormones with the effect of fermenting yeast: Biochemistry transformation of oestrogen ester in alpha- estradiol Berichte der Deutschen Chemischen Gesellschaft 1938, 71:2696-2698
95. Achstetter T Wolf DH Proteinases, proteolysis and biological control in the yeast Saccharomyces cerevisiae Yeast 1985, 1:139-157 3916861
96. Glanzer BI Faber K Griengl H Microbial Resolution of O-Acetylpantoyl Lactone Enzyme and Microbial Technology 1988, 10:689-690
97. Shimizu H Ogawa J Kataoka M Kobayashi M Screening of novel microbial enzymes for the production of biologically and chemically useful compounds Advances in biochemical engineering biotechnology, New enzymes for organic synthesis New York: Springer Scheper T 1997, 58:45-88
98. Robins K Gilligan T Microbial resolution of racemic 2,2-dimethylcyclopropanecarboxamide in the manufacture of the acid (EP 502525 A1) 1992
99. Crosby J Synthesis of Optically Active Compounds - A Large Scale Perspective Tetrahedron 1991, 47:4789-4846
100. Sheldon RA Chirotechnology New York: Marcel Dekker Inc 1993
101. May O Verseck S Bommarius A Drauz K Development of dynamic kinetic resolution processes for biocatalytic production of natural and nonnatural L-amino acids Organic Process Research & Development 2002, 6:452-457
102. Labuschagne M Botes AL Albertyn J Cloning and sequencing of an epoxide hydrolase gene from Rhodosporidium paludigenum Dna Sequence 2004, 15:202-205 15497443
103. Crout DHG Dalton H Hutchinson DW Miyagoshi M Studies on Pyruvate Decarboxylase - Acyloin Formation from Aliphatic, Aromatic and Heterocyclic Aldehydes Journal of the Chemical Society-Perkin Transactions 1 1991, 1329-1334
104. Pohl M Protein design on pyruvate decarboxylase (PDC) by site-directed mutagenesis New enzymes for organic synthesis Berlin, Heidelberg, New York: Springer Scheper T 1999, 15
105. Fuganti C Grasselli P Transformations of non-conventional substrates by fermenting baker's yeast: Production of optically active methyl-diols from aldehydes Chemistry & Industry (London, UK) 1977, 983
106. Fuganti C Grasselli P Baker's yeast-mediated synthesis of natural products Biocatalysis in Agricultural Biotechnology Washington DC: ACS Symp Ser, Am Chem Soc Whitaker JR, Sonnet PE 1989, 359
107. Fuganti C Grasselli P Synthesis of the C-14 Chromanyl Moiety of Natural Alpha-Tocopherol (Vitamin E) Journal of the Chemical Society-Chemical Communications 1982, 205-206
108. Vassilev VP Uchiyama T Kajimoto T Wong CH L-Threonine aldolase in organic synthesis - preparation of novel beta-hydroxy-alpha-amino acids Tetrahedron Letters 1995, 36:4081-4084
109. Smith PF Hendlin D Mechanism of Phenylacetylcarbinol Synthesis by Yeast Journal of Bacteriology 1953, 65:440-445 169548 13069399
110. Cheetham PSJ Case studies in applied biocatalysis - from ideas to products Applied Biocatalysis Harwood, USA: Academic Publishers Cabral JMS, Best D, Boross L, Tramper J 1994, 87-89
111. Kieslich K Biotransformations of Industrial Use Acta Biotechnologica 1991, 11:559-570
112. Hasegawa J Ogura M Kanema H Noda N Kawaharada H Watanabe K Production of D-β-hydroxyisobutyric acid from isobutyric acid by Candida rugosa and its mutant Journal of Fermentation Technology 1982, 60:501-508
113. Zmijewski MJ Vicenzi J Landen BE Muth W Marler P Anderson B Enantioselective reduction of 3,4-methylene-dioxyphenylacetone using Candida famata and Zygosaccharomyces rouxii Applied Microbiology and Biotechnology 1997, 47:162-166
114. Anderson BA Hansen MM Harkness AR Henry CL Vicenzi JT Zmijewski MJ Application of A Practical Biocatalytic Reduction to An Enantioselective Synthesis of the 5H-2,3-Benzodiazepine Ly300164 Journal of the American Chemical Society 1995, 117:12358-12359
115. Vicenzi JT Zmijewski MJ Reinhard MR Landen BE Muth WL Marler PG Large-scale stereoselective enzymatic ketone reduction with in situ product removal via polymeric adsorbent resins Enzyme and Microbial Technology 1997, 20:494-499
116. Zaks A Dodds DR Application of biocatalysis and biotransformations to the synthesis of pharmaceuticals Drug Discovery Today 1997, 2:513-531
117. Patel RN Stereoselective biotransformations in synthesis of some pharmaceutical intermediates Advances in Applied Microbiology 1997, 43:91-140 9097413
118. Patel RN Mcnamee CG Banerjee A Howell JM Robison RS Szarka LJ Stereoselective reduction of β-keto-esters by Geotrichum candidum Enzyme and Microbial Technology 1992, 14:731-738
119. Chartrain M Roberge C Chung J McNamara J Zhao DL Olewinski R Hunt G Salmon P Roush D Yamazaki S et al Asymmetric bioreduction of (2-(4-nitro-phenyl)-N-(2-oxo-2-pyridin-3-yl-ethyl)-acetamide) to its corresponding (R) alcohol [(R)-N-(2-hydroxy-2-pyridin-3-yl-ethyl)-2-(4-nitro-phenyl)-acetamide] by using Candida sorbophila MY 1833 Enzyme and Microbial Technology 1999, 25:489-496
120. Chung JYL Ho GJ Chartrain M Roberge C Zhao DL Leazer J Farr R Robbins M Emerson K Mathre DJ et al Practical chemoenzymatic synthesis of a 3-pyridylethanolamino beta-3 adrenergic receptor agonist Tetrahedron Letters 1999, 40:6739-6743
121. Nanduri VB Hanson RL Goswami A Wasylyk JM LaPorte TL Katipally K Chung HJ Patel RN Biochemical approaches to the synthesis of ethyl 5-(S)-hydroxyhexanoate and 5-(S)-hydroxyhexanenitrile Enzyme and Microbial Technology 2001, 28:632-636
122. Patel RN Enzymatic synthesis of chiral intermediates for Omapatrilat, an antihypertensive drug Biomolecular Engineering 2001, 17:167-182 11337276
123. Hanson RL Howell JM LaPorte TL Donovan MJ Cazzulino DL Zannella V Montana MA Nanduri VB Schwarz SR Eiring RF et al Synthesis of allysine ethylene acetal using phenylalanine dehydrogenase from Thermoactinomyces intermedius Enzyme and Microbial Technology 2000, 26:348-358
124. Hanson RL Schwinden MD Banerjee A Brzozowski DB Chen BC Patel BP Mcnamee CG Kodersha GA Kronenthal DR Patel RN et al Enzymatic synthesis of L-6-hydroxynorleucine Bioorganic & Medicinal Chemistry 1999, 7:2247-2252 10579533
125. Schmidt-Kastner G Egerer P Amino acids and peptides Biotechnology Weinheim: Verlag Chemie Kieslich K 1984, 6a:387-419
126. Nonconventional Yeasts in Biotechnology. A Handbook Berlin: Springer 1996
127. Porro D Mattanovich D Recombinant Protein Production in Yeasts Methods in Molecular Biology Totowa, NJ, USA: Humana Press Balbás P, Lorence A 2004, 241:258 15269428
128. Gellissen G Heterologous protein production in methylotrophic yeasts Applied Microbiology and Biotechnology 2000, 54:741-750
129. Hollenberg CP Gellissen G Production of recombinant proteins by methylotrophic yeasts Current Opinion in Biotechnology 1997, 8:554-560 9353229
130. Gellissen G Hollenberg CP Application of yeasts in gene expression studies: A comparison of Saccharomyces cerevisiae, Hansenula polymorpha and Kluyveromyces lactis - a review Gene 1997, 190:87-97 9185853
131. Hansen H Hollenberg CP Hansenula polymorpha (Pichia angusta) Nonconventional Yeasts in Biotechnology Heidelberg: Springer Wolf K 1996, 293-311
132. Cereghino JL Cregg JM Heterologous protein expression in the methylotrophic yeast Pichia pastoris Fems Microbiology Reviews 2000, 24:45-66 10640598
133. Cregg JM Cereghino JL Shi JY Higgins DR Recombinant protein expression in Pichia pastoris Molecular Biotechnology 2000, 16:23-52 11098467
134. Sreekrishna K Kropp K Pichia pastoris Nonconventional Yeasts in Biotechnology Heidelberg: Springer Wolf K 1996, 203-252
135. van Ooyen AJJ Dekker P Huang M Olsthoorn MMA Jacobs DI Colussi PA Taron CH Heterologous protein production in the yeast Kluyveromyces lactis Fems Yeast Research 2006, 6:381-392 16630278
136. Madzak C Gaillardin C Beckerich JM Heterologous protein expression and secretion in the non-conventional yeast Yarrowia lipolytica: A review Journal of Biotechnology 2004, 109:63-81 15063615
137. Giga-Hama Y Kumagai H Expression system for foreign genes using the fission yeast Schizosaccharomyces pombe Biotechnology and Applied Biochemistry 1999, 30:235-244
138. Bailey JE Toward A Science of Metabolic Engineering Science 1991, 252:1668-1675 2047876
139. Cameron DC Tong IT Cellular and Metabolic Engineering - An Overview Applied Biochemistry and Biotechnology 1993, 38:105-140
140. Stephanopoulos G Metabolic fluxes and metabolic engineering Metabolic Engineering 1999, 1:1-11 10935750
141. Ostergaard S Olsson L Nielsen J Metabolic engineering of Saccharomyces cerevisiae Microbiology and Molecular Biology Reviews 2000, 64:34
142. Nielsen J Metabolic engineering Applied Microbiology and Biotechnology 2001, 55:263-283
143. Stephanopoulos GN Aristidou AA Nielsen J Metabolic Engineering: Principles and Methodologies San Diego: Academic Press 1998
144. Lee SY Papoutsakis ET Metabolic engineering New York: Marcel Dekker, Inc 1999
145. Werpy T Petersen G Aden A Bozell J Holladay J White J Manheim A Elliot D Lasure L Jones S et al Results of screening for potential candidates from sugars and synthesis gas Top value added chemicals from biomass Washington, DC: U.S. Department of Energy Werpy T, Petersen G 2004, 76
146. Zaldivar J Nielsen J Olsson L Fuel ethanol production from lignocellulose: A challenge for metabolic engineering and process integration Applied Microbiology and Biotechnology 2001, 56:17-34
147. Hahn-Haegerdal B Karhumaa K Fonseca C Spencer-Martins I Gorwa-Grauslund MF Towards industrial pentose-fermenting yeast strains Applied Microbiology and Biotechnology 2007, 74:937-953
148. Hahn-Haegerdal B Karhumaa K Jeppsson M Gorwa-Grauslund MF Metabolic engineering for pentose utilization in Saccharomyces cerevisiae Biofuels Berlin, Heidelberg: Springer 2007, 147-177
149. Kim MD Jeun YS Kim SG Ryu YW Seo JH Comparison of xylitol production in recombinant Saccharomyces cerevisiae strains harboring XYL1 gene of Pichia stipitis and GRE3 gene of S. cerevisiae Enzyme and Microbial Technology 2002, 31:862-866
150. Granstroem TB Izumori K Leisola M A rare sugar xylitol. Part I: The biochemistry and biosynthesis of xylitol Applied Microbiology and Biotechnology 2007, 74:277-281
151. Shieh WR Gopalan AS Sih CJ Stereochemical Control of Yeast Reductions 5. Characterization of the Oxidoreductases Involved in the Reduction of Beta-Keto-Esters Journal of the American Chemical Society 1985, 107:2993-2994
152. Rodriguez S Kayser MM Stewart JD Highly stereoselective reagents for beta-keto ester reductions by genetic engineering of baker's yeast Journal of the American Chemical Society 2001, 123:1547-1555 11456752
153. Katz M Hahn-Haegerdal B Gorwa-Grauslund MF Screening of two complementary collections of Saccharomyces cerevisiae to identify enzymes involved in stereo-selective reductions of specific carbonyl compounds: An alternative to protein purification Enzyme and Microbial Technology 2003, 33:163-172
154. Johanson T Katz M Gorwa-Grauslund MF Strain engineering for stereoselective bioreduction of dicarbonyl compounds by yeast reductases Fems Yeast Research 2005, 5:513-525 15780652
155. Johanson T Carlquist M Olsson C Rudolf A Frejd T Gorwa-Grauslund MF Reaction and strain engineering for improved stereo-selective whole-cell reduction of a bicyclic diketone Applied Microbiology and Biotechnology 2008, 77:1111-1118
156. Almqvist F Torstensson L Gudmundsson A Frejd T New ligands for the titanium(IV)-induced asymmetric reduction of ketones with catecholborane Angewandte Chemie-International Edition in English 1997, 36:376-377
157. Mori K Nagano E Preparative bioorganic chemistry. Part 10. Asymmetric reductions of bicyclo[2.2.2]octane-2,6-diones with baker's yeast Biocatalysis 1990, 3:25-36
158. Kratzer R Egger S Nidetzky B Integration of enzyme, strain and reaction engineering to overcome limitations of baker's yeast in the asymmetric reduction of α-keto esters Biotechnology and Bioengineering 2008 101002/bit.21980.
159. Kratzer R Nidetzky B Identification of Candida tenuis xylose reductase as highly selective biocatalyst for the synthesis of aromatic alpha-hydroxy esters and improvement of its efficiency by protein engineering Chemical Communications 2007, 1047-1049 17325801
160. Farhi M Dudareva N Masci T Weiss D Vainstein A Abeliovich H Synthesis of the food flavoring methyl benzoate by genetically engineered Saccharomyces cerevisiae Journal of Biotechnology 2006, 122:307-315 16442655
161. González-Candelas L Gil JV Lamuela-Raventós RM Ramón D The use of transgenic yeasts expressing a gene encoding a glycosyl-hydrolase as a tool to increase resveratrol content in wine International Journal of Food Microbiology 2000, 59:179-183 11020039
162. Jang MS Cai EN Udeani GO Slowing KV Thomas CF Beecher CWW Fong HHS Farnsworth NR Kinghorn AD Mehta RG et al Cancer chemopreventive activity of resveratrol, a natural product derived from grapes Science 1997, 275:218-220 8985016
163. Subbaramaiah K Chung WJ Michaluart P Telang N Tanabe T Inoue H Jang MS Pezzuto JM Dannenberg AJ Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells Journal of Biological Chemistry 1998, 273:21875-21882 9705326
164. Genoves S Gil JV Manzanares P Aleixandre JL Valles S Candida molischiana beta-glucosidase production by Saccharomyces cerevisiae and its application in winemaking Journal of Food Science 2003, 68:2096-2100
165. Smit A Otero RRC Lambrechts MG Pretorius IS Van Rensburg P Enhancing volatile phenol concentrations in wine by expressing various phenolic acid decarboxylase genes in Saccharomyces cerevisiae Journal of Agricultural and Food Chemistry 2003, 51:4909-4915
166. Cordente AG Swiegers JH Hegardt FG Pretorius IS Modulating aroma compounds during wine fermentation by manipulating carnitine acetyltransferases in Saccharomyces cerevisiae Fems Microbiology Letters 2007, 267:159-166 17156120
167. Stewart JD Reed KW Kayser MM 'Designer yeast': A new reagent for enantioselective Baeyer-Villiger oxidations Journal of the Chemical Society-Perkin Transactions 1 1996, 755-757
168. Stewart JD Reed KW Martinez CA Zhu J Chen G Kayser MM Recombinant baker's yeast as a whole-cell catalyst for asymmetric Baeyer-Villiger oxidations Journal of the American Chemical Society 1998, 120:3541-3548
169. Stewart JD Reed KW Zhu J Chen G Kayser MM A "designer yeast" that catalyzes the kinetic resolutions of 2-alkyl-substituted cyclohexanones by enantioselective Baeyer-Villiger oxidations Journal of Organic Chemistry 1996, 61:7652-7653 11667712
170. Kayser MM Chen G Stewart JD Enantio- and regioselective Baeyer-Villiger oxidations of 2- and 3-substituted cyclopentanones using engineered bakers' yeast Journal of Organic Chemistry 1998, 63:7103-7106 11672341
171. Lee EY Yoo SS Kim HS Lee SJ Oh YK Park S Production of (S)-styrene oxide by recombinant Pichia pastoris containing epoxide hydrolase from Rhodotorula glutinis Enzyme and Microbial Technology 2004, 35:624-631
172. Hakki T Zearo S Dragan CA Bureik M Bernhardt R Coexpression of redox partners increases the hydrocortisone (cortisol) production efficiency in CYP11B1 expressing fission yeast Schizosaccharomyces pombe Journal of Biotechnology 2008, 133:351-359 17935813
173. Peters FT Dragan CA Wilde DR Meyer MR Zapp J Bureik M Maurer HH Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4 ′-hydroxymethyl-alpha-pyrrolidinobutyrophenone Biochemical Pharmacology 2007, 74:511-520 17572388
174. Leonida MD Redox enzymes used in chiral syntheses coupled to coenzyme regeneration Current Medicinal Chemistry 2001, 8:345-369 11172694
175. Donk van der WA Zhao HM Recent developments in pyridine nucleotide regeneration Current Opinion in Biotechnology 2003, 14;421-426 12943852
176. Endo T Koizumi S Microbial conversion with cofactor regeneration using genetically engineered bacteria Advanced Synthesis & Catalysis 2001, 343:521-526
177. Zhao HM Donk van der WA Regeneration of cofactors for use in biocatalysis Current Opinion in Biotechnology 2003, 14:583-589 14662386
178. Nissen TL Anderlund M Nielsen J Villadsen J Kielland-Brandt MC Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool Yeast 2001, 18:19-32 11124698
179. Bruinenberg PM Vandijken JP Scheffers WA A theoretical analysis of NADPH
180. Bruinenberg PM Vandijken JP Scheffers WA An enzymic analysis of NADPH production and consumption in Candida utilis Journal of General Microbiology 1983, 129:965-971 6684148
181. Anderlund M Nissen TL Nielsen J Villadsen J Rydstrom J Hahn-Hagerdal B Kielland-Brandt MC Expression of the Escherichia coli pntA and pntB genes, encoding nicotinamide nucleotide transhydrogenase, in Saccharomyces cerevisiae and its effect on product formation during anaerobic glucose fermentation Applied and Environmental Microbiology 1999, 65:2333-2340
182. dos Santos MM Thygesen G Kotter P Olsson L Nielsen J Aerobic physiology of redox-engineered Saccharomyces cerevisiae strains modified in the ammonium assimilation for increased NADPH availability Fems Yeast Research 2003, 4:59-68 14554197
183. Nissen TL Kielland-Brandt MC Nielsen J Villadsen J Optimization of ethanol production in Saccharomyces cerevisiae by metabolic engineering of the ammonium assimilation Metabolic Engineering 2000, 2:69-77 10935936
184. Heux S Cachon R Dequin S Cofactor engineering in Saccharomyces cerevisiae: Expression of a H2O-forming NADH oxidase and impact on redox metabolism Metabolic Engineering 2006, 8:303-314 16473032
185. Fukuda Y Yamaguchi S Hashimoto H Shimosaka M Kimura A Cloning of Glucose Phosphorylating Genes in S. cerevisiae by the Ku-Method and Application to ATP Production Agricultural and Biological Chemistry 1984, 48:2877-2881
186. Chen RRZ Permeability issues in whole-cell bioprocesses and cellular membrane engineering Applied Microbiology and Biotechnology 2007, 74:730-738
187. Liu Y Hama H Fujita Y Kondo A Inoue Y Kimura A Fukuda H Production of S-lactoylglutathione by high activity whole cell biocatalysts prepared by permeabilization of recombinant Saccharomyces cerevisiae with alcohols Biotechnology and Bioengineering 1999, 64:54-60
188. Lee YJ Kim CS Oh DK Lactulose production by beta-galactosidase in permeabilized cells of Kluyveromyces lactis Applied Microbiology and Biotechnology 2004, 64:787-793
189. Kubal BS D'Souza SF Immobilization of catalase by entrapment of permeabilized yeast cells in hen egg white using glutaraldehyde Journal of Biochemical and Biophysical Methods 2004 59:61-64
190. Upadhya R Nagajyothi Bhat SG Stabilization of D-amino acid oxidase and catalase in permeabilized Rhodotorula gracilis cells and its application for the preparation of alpha-ketoacids Biotechnology and Bioengineering 2000, 68:430-436
191. Isoai A Kimura H Reichert A Schorgendorfer K Nikaido K Tohda H Giga-Hama Y Mutoh N Kumagai H Production of D-amino acid oxidase (DAO) of Trigonopsis variabilis in Schizosaccharomyces pombe and the characterization of biocatalysts prepared with recombinant cells Biotechnology and Bioengineering 2002, 80:22-32
192. Matsumoto T Takahashi S Kaieda M Ueda M Tanaka A Fukuda H Kondo A Yeast whole-cell biocatalyst constructed by intracellular overproduction of Rhizopus oryzae lipase is applicable to biodiesel fuel production Applied Microbiology and Biotechnology 2001, 57:515-520
193. Fontanille P Larroche C Optimization of isonovalal production from alpha-pinene oxide using permeabilized cells of Pseudomonas rhodesiae CIP 107491 Applied Microbiology and Biotechnology 2003, 60:534-540
194. Schreuder MP Mooren ATA Toschka HY Verrips CT Klis FM Immobilizing proteins on the surface of yeast cells Trends in Biotechnology 1996, 14:115-120 8936431
195. Shimazu M Mulchandani A Chen W Cell surface display of organophosphorus hydrolase using ice nucleation protein Biotechnology Progress 2001, 17:76-80 11170483
196. Fukuda T Isogawa D Takagi M Kato-Murai M Kimoto H Kusaoke H Ueda M Suye SI Yeast cell-surface expression of chitosanase from Paenibacillus fukuinensis Bioscience Biotechnology and Biochemistry 2007, 71:2845-2847
197. Matsumoto T Ito M Fukuda H Kondo A Enantioselective transesterification using lipase-displaying yeast whole-cell biocatalyst Applied Microbiology and Biotechnology 2004, 64:481-485
198. Matsumoto T Fukuda H Ueda M Tanaka A Kondo A Construction of yeast strains with high cell surface lipase activity by using novel display systems based on the Flo1p flocculation functional domain Applied and Environmental Microbiology 2002, 68:4517-4522
199. Nakamura Y Matsumoto T Nomoto F Ueda M Fukuda H Kondo A Enhancement of activity of lipase-displaying yeast cells and their application to optical resolution of (R, S)-1-benzyloxy-3-chloro-2-propyl monosuccinate Biotechnology Progress 2006, 22:998-1002 16889376
200. Shibamoto H Matsumoto T Fukuda H Kondo A Molecular engineering of Rhizopus oryzae lipase using a combinatorial protein library constructed on the yeast cell surface Journal of Molecular Catalysis B: Enzymatic 2004, 28:235-239
201. Kaya M Ito J Kotaka A Matsumura K Bando H Sahara H Ogino C Shibasaki S Kuroda K Ueda M et al Isoflavone aglycones production from isoflavone glycosides by display of beta-glucosidase from Aspergillus oryzae on yeast cell surface Applied Microbiology and Biotechnology 2008, 79:51-60
202. Kim HJ Lee JH Kim HC Lee JW Kim YH Nam SW Characterization of cyclofructans from inulin by Saccharomyces cerevisiae strain displaying cell-surface cycloinulooligosaccharide fructanotransferase Journal of Microbiology and Biotechnology 2007, 17:695-700
203. Lipovsek D Antipov E Armstrong KA Olsen MJ Klibanov AM Tidor B Wittrup KD Selection of horseradish peroxidase variants with enhanced enantioselectivity by yeast surface display Chemistry & Biology 2007, 14:1176-1185 17961829
204. Kato M Fuchimoto J Tanino T Kondo A Fukuda H Ueda M Preparation of a whole-cell biocatalyst of mutated Candida antarctica lipase B (mCALB) by a yeast molecular display system and its practical properties Applied Microbiology and Biotechnology 2007, 75:549-555
205. Zhang NY Suen WC Windsor W Xiao L Madison V Zaks A Improving tolerance of Candida antarctica lipase B towards irreversible thermal inactivation through directed evolution Protein Engineering 2003, 16:599-605 12968077
206. Ueda M Tanaka A Cell surface engineering of yeast: Construction of arming yeast with biocatalyst Journal of Bioscience and Bioengineering 2000, 90:125-136
207. Wu CH Mulchandani A Chen W Versatile microbial surface-display for environmental remediation and biofuels production Trends in Microbiology 2008, 16:181-188 18321708
208. Fujita Y Katahira S Ueda M Tanaka A Okada H Morikawa Y Fukuda H Kondo A Construction of whole-cell biocatalyst for xylan degradation through cell-surface xylanase display in Saccharomyces cerevisiae Journal of Molecular Catalysis B: Enzymatic 2002, 17:189-195
209. Fujita Y Ito J Ueda M Fukuda H Kondo A Synergistic saccharification, and direct fermentation to ethanol, of amorphous cellulose by use of an engineered yeast strain codisplaying three types of cellulolytic enzyme Applied and Environmental Microbiology 2004, 70:1207-1212
210. Fleet GH Cell walls The Yeasts. Yeasts Organelles London: Academic Press Rose AH, Harrison JS 2 1991, 4:199-278
211. Klis FM Cell-Wall Assembly in Yeast Yeast 1994, 10:851-869 7985414
212. Jiang ZB Gao B Ren R Tao XY Ma YS Wei DZ Efficient display of active lipase LipB52 with a Pichia pastoris cell surface display system and comparison with the LipB52 displayed on Saccharomyces cerevisiae cell surface Bmc Biotechnology 2008, 8:2267-459 18221563
213. Yue LX Chi ZM Wang L Liu J Madzak C Li J Wang XG Construction of a new plasmid for surface display on cells of Yarrowia lipolytica Journal of Microbiological Methods 2008, 72:116-123 18155308
214. O'Hagan D The Polyketide Metabolites Chichester, UK: Ellis Horwood 1991
215. Mutka SC Bondi SM Carney JR Da Silva NA Kealey JT Metabolic pathway engineering for complex polyketide biosynthesis in Saccharomyces cerevisiae Fems Yeast Research 2006, 6:40-47 16423069
216. Misawa N Nakagawa M Kobayashi K Yamano S Izawa Y Nakamura K Harashima K Elucidation of the Erwinia uredovora carotenoid biosynthetic pathway by functional analysis of gene products expressed in Escherichia coli Journal of Bacteriology 1990, 172:6704-6712 210783 2254247
217. Misawa N Satomi Y Kondo K Yokoyama A Kajiwara S Saito T Ohtani T Miki W Structure and functional analysis of a marine bacterial carotenoid biosynthesis gene cluster and astaxanthin biosynthetic pathway proposed at the gene level Journal of Bacteriology 1995, 177:6575-6584 177511 7592436
218. Shimada H Kondo K Fraser PD Miura Y Saito T Misawa N Increased carotenoid production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway Applied and Environmental Microbiology 1998, 64:2676-2680
219. Miura Y Kondo K Saito T Shimada H Fraser PD Misawa N Production of the carotenoid lycopene, beta-carotene, and astaxanthin in the food yeast Candida utilis Applied and Environmental Microbiology 1998, 64:1226-1229
220. Misawa N Shimada H Metabolic engineering for the production of carotenoids in non-carotenogenic bacteria and yeasts Journal of Biotechnology 1998, 59:169-181
221. Yamano S Ishii T Nakagawa M Ikenaga H Misawa N Metabolic engineering for production of beta-carotene and lycopene in Saccharomyces cerevisiae Bioscience Biotechnology and Biochemistry 1994, 58;1112-1114
222. Ausich RL Brinkhaus FL Mukharji I Proffitt JH Yarger JG Yen HCB Biosynthesisof carotenoids in genetically engineered hosts (WO 9113078) 1991, 311 4-3-1991.
223. Ausich RL Production of Carotenoids by Recombinant DNA Technology Pure and Applied Chemistry 1994, 66:1057-1062
224. Daum G Lees ND Bard M Dickson R Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae Yeast 1998, 14:1471-1510 9885152
225. Dimster-Denk D Rine J Phillips J Scherer S Cundiff P DeBord K Gilliland D Hickman S Jarvis A Tong L et al Comprehensive evaluation of isoprenoid biosynthesis regulation in Saccharomyces cerevisiae utilizing the Genome Reporter Matrix (TM) Journal of Lipid Research 1999, 40:850-860 10224154
226. Ro DK Paradise EM Ouellet M Fisher KJ Newman KL Ndungu JM Ho KA Eachus RA Ham TS Kirby J et al Production of the antimalarial drug precursor artemisinic acid in engineered yeast Nature 2006, 440:940-943 16612385
227. Shiba Y Paradise EM Kirby J Ro D-K Keasling JD Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids Metabolic Engineering 2007, 9:160-168 17196416
228. Szczebara FM Chandelier C Villeret C Masurel A Bourot S Duport C Blanchard S Groisillier A Testet E Costaglioli P et al Total biosynthesis of hydrocortisone from a simple carbon source in yeast Nature Biotechnology 2003, 21:143-149 12514739
229. Jackson BE Hart-Wells EA Matsuda SPT Metabolic engineering to produce sesquiterpenes in yeast Organic Letters 2003, 5:1629-1632 12735738
230. Dejong JM Liu YL Bollon AP Long RM Jennewein S Williams D Croteau RB Genetic engineering of Taxol biosynthetic genes in Saccharomyces cerevisiae Biotechnology and Bioengineering 2006, 93:212-224
231. Wattanachaisaereekul S Lantz AE Nielsen ML Andresson OS Nielsen J Optimization of heterologous production of the polyketide 6-MSA in Saccharomyces cerevisiae Biotechnology and Bioengineering 2007, 97:893-900
232. Kealey JT Liu L Santi DV Betlach MC Barr PJ Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts Proceedings of the National Academy of Sciences of the United States of America 1998, 95:505-509 18449 9435221
233. Ro DK Douglas CJ Reconstitution of the entry point of plant phenylpropanoid metabolism in yeast (Saccharomyces cerevisiae) - Implications for control of metabolic flux into the phenylpropanoid pathway Journal of Biological Chemistry 2004, 279:2600-2607 14607837
234. Vannelli T Qi WW Sweigard J Gatenby AA Sariaslani FS Production of p-hydroxycinnamic acid from glucose in Saccharomyces cerevisiae and Escherichia coli by expression of heterologous genes from plants and fungi Metabolic Engineering 2007, 9:142-151 17204442
235. Jiang HX Wood KV Morgan JA Metabolic engineering of the phenylpropanoid pathway in Saccharomyces cerevisiae Applied and Environmental Microbiology 2005, 71:2962-2969
236. Beekwilder J Meer van der IM Sibbesen O Broekgaarden M Qvist I Mikkelsen JD Hall RD Microbial production of natural raspberry ketone Journal of Biotechnology 2007, 2:1270-1279
237. Larsen M Poll L Callesen O Lewis M Relations Between the Content of Aroma Compounds and the Sensory Evaluation of 10 Raspberry Varieties (Rubus Idaeus L) Acta Agriculturae Scandinavica 1991, 41:447-454
238. Becker JVW Armstrong GO Merwe Van der MJ Lambrechts MG Vivier MA Pretorius IS Metabolic engineering of Saccharomyces cerevisiae for the synthesis of the wine-related antioxidant resveratrol Fems Yeast Research 2003, 4:79-85 14554199
239. Beekwilder J Wolswinkel R Jonker H Hall R De Vos CHR Bovy A Production of resveratrol in recombinant microorganisms Applied and Environmental Microbiology 2006, 72:5670-5672
240. Branduardi P Fossati T Sauer M Pagani R Mattanovich D Porro D Biosynthesis of vitamin C by yeast leads to increased stress resistance PLoS ONE 2007, 2:e1092 2034532 17971855
241. Duport C Spagnoli R Degryse E Pompon D Self-sufficient biosynthesis of pregnenolone and progesterone in engineered yeast Nature Biotechnology 1998, 16:186-189 9487528
242. Crowley JH Leak FW Shianna KV Tove S Parks LW A mutation in a purported regulatory gene affects control of sterol uptake in Saccharomyces cerevisiae Journal of Bacteriology 1998, 180:4177-4183 107415 9696767
243. Gokhale RS Hunziker D Cane DE Khosla C Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase Chemistry & Biology 1999, 6;117-125 10021418
244. Regentin R Kennedy J Wu N Carney JR Licari P Galazzo J Desai R Precursor-directed biosynthesis of novel triketide lactones Biotechnology Progress 2004, 20:122-127 14763833
245. Hani J Feldmann H tRNA genes and retroelements in the yeast genome Nucleic Acids Research 1998, 26;689-696 147333 9443958