Self-sufficient biosynthesis of pregnenolone and progesterone in engineered yeast

Nature Biotechnology

Volumn 16, Issue 2, 1998, Pages 186-189

  Duport, Catherine ^a   Spagnoli, Roberto ^b   Degryse, Eric ^c   Pompon, Denis ^a  

^a CNRS   (France)

^b Biotechnology Department   (France)

^c TRANSGENE S A   (France)

Author keywords

Metabolic engineering; Saccharomyces cerevisiae; Steroid

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ADRENODOXIN; CARBON; CHOLESTEROL; CYTOCHROME P450; ENZYME; ERGOSTEROL; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; GALACTOSE; ISOMERASE; PHOSPHOGLYCERATE KINASE; PREGNENOLONE; PROGESTERONE; STEROID;

ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; ENGINEERING; GAS CHROMATOGRAPHY; GENE; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; STEROL SYNTHESIS;

ADRENODOXIN; ANIMALS; ARABIDOPSIS; CATTLE; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; CHROMATOGRAPHY, GAS; CYTOCHROME P-450 ENZYME SYSTEM; FERREDOXIN-NADP REDUCTASE; GALACTOSE; GENE TRANSFER TECHNIQUES; GENETIC ENGINEERING; HUMANS; MULTIENZYME COMPLEXES; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PREGNENOLONE; PROGESTERONE; PROGESTERONE REDUCTASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; STEROID ISOMERASES;

ARABIDOPSIS; ARABIDOPSIS THALIANA; BOVINAE; SACCHAROMYCES CEREVISIAE;

EID: 0031936276     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt0298-186     Document Type: Article

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