메뉴 건너뛰기




Volumn 2, Issue 1, 2000, Pages 69-77

Optimization of ethanol production in Saccharomyces cerevisiae by metabolic engineering of the ammonium assimilation

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ADENOSINE TRIPHOSPHATE; ALCOHOL PRODUCTION; AMMONIA; ANAEROBIC FERMENTATION; BIOCHEMICAL PATHWAY; BIOSYNTHESIS; ETHANOL; FUNGAL GROWTH; GENETIC STRAIN; GLUTAMATE AMMONIA LIGASE; GLUTAMATE DEHYDROGENASE; GLUTAMATE SYNTHASE; GLYCEROL; METABOLIC ENGINEERING; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROCESS OPTIMIZATION; WILD RELATIVE;

EID: 0033929520     PISSN: 10967176     EISSN: None     Source Type: Journal    
DOI: 10.1006/mben.1999.0140     Document Type: Article
Times cited : (184)

References (28)
  • 1
    • 0002587184 scopus 로고
    • Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for the growth in a defined medium
    • Andreasen A. A., Stier T. J. B. Anaerobic nutrition of Saccharomyces cerevisiae. I. Ergosterol requirement for the growth in a defined medium. J. Cell. Comp. Physiol. 41:1953;23-36.
    • (1953) J. Cell. Comp. Physiol. , vol.41 , pp. 23-36
    • Andreasen, A.A.1    Stier, T.J.B.2
  • 2
    • 0030908893 scopus 로고    scopus 로고
    • +-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation
    • +-dependent glycerol 3-phosphate dehydrogenase encoded by GPD1 and GPD2 have distinct roles in osmoadaptation and redox regulation. EMBO J. 16:1997;2179-2187.
    • (1997) EMBO J. , vol.16 , pp. 2179-2187
    • Ansell, R.1    Granath, K.2    Hohmann, S.3    Thevelein, J.M.4    Adler, L.5
  • 3
    • 0030885616 scopus 로고    scopus 로고
    • GDH3 encodes a glutamate dehydrogenase isozyme, a previously unrecognized route for glutamate biosynthesis in Saccharomyces cerevisiae
    • Avendanõ A., Deluna A., Olivera H., Valenzuela L., Gonzales A. GDH3 encodes a glutamate dehydrogenase isozyme, a previously unrecognized route for glutamate biosynthesis in Saccharomyces cerevisiae. J. Bacteriol. 179:1997;5594-5597.
    • (1997) J. Bacteriol. , vol.179 , pp. 5594-5597
    • Avendanõ, A.1    Deluna, A.2    Olivera, H.3    Valenzuela, L.4    Gonzales, A.5
  • 5
    • 0242475404 scopus 로고    scopus 로고
    • Physiological response to anaerobicity of glycerol 3-phosphate dehydrogenase mutants of Saccharomyces cerevisiae
    • Björkqvist S., Ansell R., Adler L., Lidén G. Physiological response to anaerobicity of glycerol 3-phosphate dehydrogenase mutants of Saccharomyces cerevisiae. Appl. Environ. Microbiol. 63:1997;128-132.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 128-132
    • Björkqvist, S.1    Ansell, R.2    Adler, L.3    Lidén, G.4
  • 6
    • 0027524880 scopus 로고
    • The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant
    • Boles E., Lehnert W., Zimmermann F. K. The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant. Eur. J. Biochem. 217:1993;469-477.
    • (1993) Eur. J. Biochem. , vol.217 , pp. 469-477
    • Boles, E.1    Lehnert, W.2    Zimmermann, F.K.3
  • 7
    • 0020626034 scopus 로고
    • An enzymatic analysis of NADPH production and consumption in Candida utilis
    • Bruinenberg P. M., van Dijken J. P., Scheffers W. A. An enzymatic analysis of NADPH production and consumption in Candida utilis. J. Gen. Microbiol. 129:1983;965-971.
    • (1983) J. Gen. Microbiol. , vol.129 , pp. 965-971
    • Bruinenberg, P.M.1    Van Dijken, J.P.2    Scheffers, W.A.3
  • 8
    • 0029347214 scopus 로고
    • Acoustic off-gas analyser for bioreactors: Precision, accuracy and dynamics of detection
    • Christensen L. H., Schulze U., Nielsen J., Villadsen J. Acoustic off-gas analyser for bioreactors: Precision, accuracy and dynamics of detection. Chem. Eng. Sci. 50:1995;2601-2610.
    • (1995) Chem. Eng. Sci. , vol.50 , pp. 2601-2610
    • Christensen, L.H.1    Schulze, U.2    Nielsen, J.3    Villadsen, J.4
  • 9
    • 0028925047 scopus 로고
    • Saccharomyces cerevisiae has a single glutamate synthase gene coding for a plant-like high-molecular-weight polypeptide
    • Cogoni C., Valenzuela L., Gonzáles-Halphen D., Olivera H., Macino G., Ballario P., Gonzáles A. Saccharomyces cerevisiae has a single glutamate synthase gene coding for a plant-like high-molecular-weight polypeptide. J. Bacteriol. 177:1995;792-798.
    • (1995) J. Bacteriol. , vol.177 , pp. 792-798
    • Cogoni, C.1    Valenzuela, L.2    Gonzáles-Halphen, D.3    Olivera, H.4    Macino, G.5    Ballario, P.6    Gonzáles, A.7
  • 10
    • 0025882878 scopus 로고
    • Physiological and genetic analysis of the carbon regulation of the NAD-dependent glutamate dehydrogenase of Saccharomyces cerevisiae
    • Coschigano P. W., Miller S. M., Magasanik B. Physiological and genetic analysis of the carbon regulation of the NAD-dependent glutamate dehydrogenase of Saccharomyces cerevisiae. Mol. Cell. Biol. 11:1991;4455-4465.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4455-4465
    • Coschigano, P.W.1    Miller, S.M.2    Magasanik, B.3
  • 11
    • 0023954446 scopus 로고
    • Regulation of nitrogen assimilation in Saccharomyces cerevisiae: Roles of the URE2 and GLN3 genes
    • Courchesne W. S., Magasanik B. Regulation of nitrogen assimilation in Saccharomyces cerevisiae: Roles of the URE2 and GLN3 genes. J. Bacteriol. 170:1988;708-713.
    • (1988) J. Bacteriol. , vol.170 , pp. 708-713
    • Courchesne, W.S.1    Magasanik, B.2
  • 12
    • 0024337652 scopus 로고
    • Ammonia assimilation by Candida albicans and other yeasts: Evidence for the activity of glutamate synthase
    • Holmes A. R., Collins A., Farnden K. J. F., Shepherd M. G. Ammonia assimilation by Candida albicans and other yeasts: Evidence for the activity of glutamate synthase. J. Gen. Microbiol. 135:1989;1423-1430.
    • (1989) J. Gen. Microbiol. , vol.135 , pp. 1423-1430
    • Holmes, A.R.1    Collins, A.2    Farnden, K.J.F.3    Shepherd, M.G.4
  • 13
    • 0027756102 scopus 로고
    • A gene encoding sn-glycerol 3-phosphate dehydrogenase (NAD+) complements an osmosensitive mutant of Saccharomyces cerevisiae
    • Larsson K., Ansell R., Eriksson P., Adler L. A gene encoding sn-glycerol 3-phosphate dehydrogenase (NAD+) complements an osmosensitive mutant of Saccharomyces cerevisiae. Mol. Microbiol. 10:1993;1101-1111.
    • (1993) Mol. Microbiol. , vol.10 , pp. 1101-1111
    • Larsson, K.1    Ansell, R.2    Eriksson, P.3    Adler, L.4
  • 14
    • 0020678872 scopus 로고
    • Purification and properties of glutamine synthetase from Saccharomyces cerevisiae
    • Mitchell A. P., Magasanik B. Purification and properties of glutamine synthetase from Saccharomyces cerevisiae. J. Biol. Chem. 258:1983;119-124.
    • (1983) J. Biol. Chem. , vol.258 , pp. 119-124
    • Mitchell, A.P.1    Magasanik, B.2
  • 15
    • 0025063371 scopus 로고
    • Role of the NAD-linked glutamate dehydrogenase in nitrogen metabolism in Saccharomyces cerevisiae
    • Miller S. M., Magasanik B. Role of the NAD-linked glutamate dehydrogenase in nitrogen metabolism in Saccharomyces cerevisiae. J. Bacteriol. 172:1990;4927-4935.
    • (1990) J. Bacteriol. , vol.172 , pp. 4927-4935
    • Miller, S.M.1    Magasanik, B.2
  • 16
    • 0025932253 scopus 로고
    • Role of the complex upstream region of the GDH2 gene in nitrogen regulation of the NAD-linked glutamate dehydrogenase in Saccharomyces cerevisiae
    • Miller S. M., Magasanik B. Role of the complex upstream region of the GDH2 gene in nitrogen regulation of the NAD-linked glutamate dehydrogenase in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:1991;6229-6247.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6229-6247
    • Miller, S.M.1    Magasanik, B.2
  • 17
    • 0021836835 scopus 로고
    • Nucleotide sequence of yeast GDH1 encoding nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenase
    • Moye W. S., Amuro N., Rao J. K. M., Zalkin H. Nucleotide sequence of yeast GDH1 encoding nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenase. J. Biol. Chem. 260:1985;8502-8508.
    • (1985) J. Biol. Chem. , vol.260 , pp. 8502-8508
    • Moye, W.S.1    Amuro, N.2    Rao, J.K.M.3    Zalkin, H.4
  • 18
    • 0031015551 scopus 로고    scopus 로고
    • Flux distributions in anaerobic, glucose-limited continuous cultivations of Saccharomyces cerevisiae
    • Nissen T. L., Schulze U., Nielsen J., Villadsen J. Flux distributions in anaerobic, glucose-limited continuous cultivations of Saccharomyces cerevisiae. Microbiology. 143:1997;203-218.
    • (1997) Microbiology , vol.143 , pp. 203-218
    • Nissen, T.L.1    Schulze, U.2    Nielsen, J.3    Villadsen, J.4
  • 20
    • 0343910032 scopus 로고    scopus 로고
    • Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis
    • Nissen T. L., Kielland-Brandt M. C., Nielsen J., Villadsen J. Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis. Yeast. 1999b.
    • (1999) Yeast
    • Nissen, T.L.1    Kielland-Brandt, M.C.2    Nielsen, J.3    Villadsen, J.4
  • 21
    • 0001778610 scopus 로고
    • Reaction products of yeast fermentations
    • Oura E. Reaction products of yeast fermentations. Process. Biochem. 12:1977;19-21.
    • (1977) Process. Biochem. , vol.12 , pp. 19-21
    • Oura, E.1
  • 22
    • 0024799254 scopus 로고
    • High efficiency transformation of intact cells using single stranded nucleic acids as a carrier
    • Schiestl R. H., Gietz R. D. High efficiency transformation of intact cells using single stranded nucleic acids as a carrier. Curr. Genet. 16:1989;339-346.
    • (1989) Curr. Genet. , vol.16 , pp. 339-346
    • Schiestl, R.H.1    Gietz, R.D.2
  • 24
    • 0022507007 scopus 로고
    • Redox balances in the metabolism of sugars by yeasts
    • van Dijken J. P., Scheffers W. A. Redox balances in the metabolism of sugars by yeasts. FEMS Microbiol. Rev. 32:1986;199-224.
    • (1986) FEMS Microbiol. Rev. , vol.32 , pp. 199-224
    • Van Dijken, J.P.1    Scheffers, W.A.2
  • 25
    • 0025318231 scopus 로고
    • Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures
    • Verduyn C., Postma E., Scheffers W. A., van Dijken J. P. Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. J. Gen. Microbiol. 136:1990;395-403.
    • (1990) J. Gen. Microbiol. , vol.136 , pp. 395-403
    • Verduyn, C.1    Postma, E.2    Scheffers, W.A.3    Van Dijken, J.P.4
  • 26
    • 0028676232 scopus 로고
    • New heterologous modules for classical or PCR-based gene disruption in Saccharomyces cerevisiae
    • Wach A., Brachat A., Pöhlmann R., Philippsen P. New heterologous modules for classical or PCR-based gene disruption in Saccharomyces cerevisiae. Yeast. 10:1994;1793-1808.
    • (1994) Yeast , vol.10 , pp. 1793-1808
    • Wach, A.1    Brachat, A.2    Pöhlmann, R.3    Philippsen, P.4
  • 27
    • 0030772483 scopus 로고    scopus 로고
    • Expression of different levels of enzymes from the Pichia stipidis XYL1 and XYL2 genes in Saccharomyces cerevisiae and its effect on product formation during xylose utilisation
    • Walfridsson M., Anderlund M., Bao X., Hahn-Hägerdahl B. Expression of different levels of enzymes from the Pichia stipidis XYL1 and XYL2 genes in Saccharomyces cerevisiae and its effect on product formation during xylose utilisation. Appl. Microbiol. Biotechnol. 48:1997;218-224.
    • (1997) Appl. Microbiol. Biotechnol. , vol.48 , pp. 218-224
    • Walfridsson, M.1    Anderlund, M.2    Bao, X.3    Hahn-Hägerdahl, B.4
  • 28
    • 0025168105 scopus 로고
    • Ethanol. Fundamentals of production from renewable feedstocks and use as a transportation fuel
    • Wyman C. E., Hinman N. D. Ethanol. Fundamentals of production from renewable feedstocks and use as a transportation fuel. Appl. Biochem. Biotech. 24/25:1990;735-753.
    • (1990) Appl. Biochem. Biotech. , vol.2425 , pp. 735-753
    • Wyman, C.E.1    Hinman, N.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.