Production of a doubly chiral compound, (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone, by two-step enzymatic asymmetric reduction

Applied and Environmental Microbiology

Volumn 69, Issue 2, 2003, Pages 933-937

  Wada, Masaru ^a   Yoshizumi, Ayumi ^a   Noda, Yumiko ^a   Kataoka, Michihiko ^b   Shimizu, Sakayu ^b   Takagi, Hiroshi ^a   Nakamori, Shigeru ^a  

^a FUKUI PREFECTURAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCATALYSTS; BIOSYNTHESIS; CHEMICAL BONDS; HYDROGENATION;

DOUBLE BONDS;

ENZYME KINETICS;

2,6,6 TRIMETHYL 2 CYCLOHEXENE 1,4 DIONE; 4 HYDROXY 2,2,6 TRIMETHYLCYCLOHEXANONE; ALCOHOL; CYCLOHEXANONE DERIVATIVE; GLUCOSE; GLUCOSE DEHYDROGENASE; LEVODIONE REDUCTASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; PHORONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ENZYME;

ARTICLE; BIOCATALYST; CHIRALITY; CONTROLLED STUDY; CORYNEBACTERIUM; CORYNEBACTERIUM AQUATICUM; CRYSTAL STRUCTURE; ENANTIOMER; ENZYME SYNTHESIS; ESCHERICHIA COLI; HYDROGENATION; NONHUMAN; PROTEIN EXPRESSION; REDUCTION; SACCHAROMYCES CEREVISIAE; STEREOCHEMISTRY; STEREOSPECIFICITY; STOICHIOMETRY; STRUCTURE ANALYSIS;

CYCLOHEXANONES; ESCHERICHIA COLI; GLUCOSE 1-DEHYDROGENASE; GLUCOSE DEHYDROGENASES; NADPH DEHYDROGENASE; SACCHAROMYCES CEREVISIAE; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

CORYNEBACTERIUM; ESCHERICHIA COLI; LEIFSONIA AQUATICA; NEGIBACTERIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037315680     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.69.2.933-937.2003     Document Type: Article

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