-
1
-
-
0001023204
-
Expression of heterologous gene products in yeast
-
Edited by Cleland JL, Craik CS. New York: Wiley Liss
-
Pichuantes S, Nguyen AT, Franzusoff A: Expression of heterologous gene products in yeast. In Protein Engineering: Principles and Practice. Edited by Cleland JL, Craik CS. New York: Wiley Liss; 1996:129-161. Overview of industrially and pharmaceutically relevant components and methods of heterologous gene expression in yeast.
-
(1996)
Protein Engineering: Principles and Practice
, pp. 129-161
-
-
Pichuantes, S.1
Nguyen, A.T.2
Franzusoff, A.3
-
2
-
-
0004048061
-
-
Berlin: Springer
-
Wolf K (Ed): Nonconventional Yeasts in Biotechnology. A Handbook. Berlin: Springer; 1996. A compilation of methods and components of biotechnological applications of 10 non-Saccharomyces yeasts. The book contains, among others, chapters on Pichia pastoris and Hansenula polymorpha (see also [52,53]).
-
(1996)
Nonconventional Yeasts in Biotechnology. A Handbook
-
-
Wolf, K.1
-
3
-
-
0030272554
-
The expression of recombinant proteins in yeasts
-
Sudbery PE: The expression of recombinant proteins in yeasts. Curr Opin Biotechnol 1996, 7:517-524.
-
(1996)
Curr Opin Biotechnol
, vol.7
, pp. 517-524
-
-
Sudbery, P.E.1
-
4
-
-
0031010051
-
Applications of yeasts in gene expression studies: A comparison of Saccharomyces cerevisiae, Hansenula polymorpha and Kluyveromyces lactis - A review
-
Gellissen G, Hollenberg CP: Applications of yeasts in gene expression studies: a comparison of Saccharomyces cerevisiae, Hansenula polymorpha and Kluyveromyces lactis - a review. Gene 1997, 190:87-97.
-
(1997)
Gene
, vol.190
, pp. 87-97
-
-
Gellissen, G.1
Hollenberg, C.P.2
-
5
-
-
0030272217
-
Quality and authenticity of heterologous proteins synthesized in yeast
-
Eckart MR, Bussineau CM: Quality and authenticity of heterologous proteins synthesized in yeast Curr Opin Biotechnol 1996, 7:525-530.
-
(1996)
Curr Opin Biotechnol
, vol.7
, pp. 525-530
-
-
Eckart, M.R.1
Bussineau, C.M.2
-
6
-
-
0028801044
-
Advances in the use of Pichia pastoris for high-level gene expression
-
Romanos M: Advances in the use of Pichia pastoris for high-level gene expression. Curr Opin Biotechnol 1995, 6:527-533.
-
(1995)
Curr Opin Biotechnol
, vol.6
, pp. 527-533
-
-
Romanos, M.1
-
7
-
-
0030600453
-
Inducible expression of a heterologous protein in Hansenula polymorpha using the alcohol oxidase 1 promoter of Pichia pastoris
-
•], demonstrates an efficient expression of heterologous proteins in H. polymorpha driven by the P. pastoris-derived alcohol oxidase 1 (AOX1) promoter. The AOX1-promotor has all the cis-acting elements necessary for proper regulation (induction by methanol and derepression under glycerol limitation) in H. polymorpha.
-
(1996)
Gene
, vol.177
, pp. 163-167
-
-
Raschke, W.C.1
Neiditch, B.R.2
Hendricks, M.3
Cregg, J.M.4
-
8
-
-
8944262345
-
Invertase secretion in Hansenula polymorpha under the AOX1 promoter from Pichia pastoris
-
•], demonstrates expression of heterologous proteins in H. polymorpha under control of the alcohol oxidase 1 promoter from P. pastoris.
-
(1996)
Yeast
, vol.12
, pp. 815-822
-
-
Rodriguez, L.1
Narciandi, R.E.2
Roca, H.3
Cremata, J.4
Montesinos, R.5
Rodriguez, E.6
Grillo, J.M.7
Muzio, V.8
Herrera, L.S.9
Delgado, J.M.10
-
10
-
-
0028187499
-
Heterologous gene expression in C1 compound-utilizing yeasts
-
Edited by Murooka Y, Imanaka T. New York: Dekker
-
Gellissen G: Heterologous gene expression in C1 compound-utilizing yeasts. In Recombinant Microbes for industrial and Agricultural Applications. Edited by Murooka Y, Imanaka T. New York: Dekker; 1994:787-796.
-
(1994)
Recombinant Microbes for Industrial and Agricultural Applications
, pp. 787-796
-
-
Gellissen, G.1
-
11
-
-
0028827506
-
Review: Methylotrophic yeasts as factories for the production of foreign proteins
-
Faber KN, Harder W, Ab G, Veenhuis M: Review: methylotrophic yeasts as factories for the production of foreign proteins. Yeast 1995, 11:1331-1344.
-
(1995)
Yeast
, vol.11
, pp. 1331-1344
-
-
Faber, K.N.1
Harder, W.2
Ab, G.3
Veenhuis, M.4
-
12
-
-
0030608045
-
High-level secretion of fungal glucoamylase using the Candida boidinii gene expression system
-
Sakai Y, Akiyama M, Kondoh H, Shibano Y, Kato N: High-level secretion of fungal glucoamylase using the Candida boidinii gene expression system. Biochim Biophys Acta 1996, 1308:81-87. Describes the high-yield production of a secreted heterologous enzyme in gram ranges. The C. boidinii system exhibits properties similar to those described for the two established methylotrophs.
-
(1996)
Biochim Biophys Acta
, vol.1308
, pp. 81-87
-
-
Sakai, Y.1
Akiyama, M.2
Kondoh, H.3
Shibano, Y.4
Kato, N.5
-
13
-
-
0029780708
-
Methylotrophic yeast Hansenula polymorpha as production organism for recombinant pharmaceuticals
-
Gellissen G, Melber K: Methylotrophic yeast Hansenula polymorpha as production organism for recombinant pharmaceuticals. Drug Res 1996, 46:943-948. A brief review on H. polymorpha as a production organism for recombinant pharmaceuticals focusing on hirudin and a H. polymorpha-derived hepatitis B vaccine. The review includes a list of FDA-approved recombinant drugs.
-
(1996)
Drug Res
, vol.46
, pp. 943-948
-
-
Gellissen, G.1
Melber, K.2
-
14
-
-
0343553856
-
Novel recombinant HB vaccine produced by a high-level expression Hansenula polymorpha yeast system
-
Lepetic A, Seigelchifer M, Arduino RC, Lazovski J, Nacinovich F, Sturba E, Stambou-lian D: Novel recombinant HB vaccine produced by a high-level expression Hansenula polymorpha yeast system. Clin Infect Dis 1996, 23:276.
-
(1996)
Clin Infect Dis
, vol.23
, pp. 276
-
-
Lepetic, A.1
Seigelchifer, M.2
Arduino, R.C.3
Lazovski, J.4
Nacinovich, F.5
Sturba, E.6
Stambou-lian, D.7
-
15
-
-
0028081167
-
High-level secretion and very efficient isotopic labelling of tick anticoagulant peptide (TAP) expressed in the methylotrophic yeast, Pichia pastoris
-
Laroche Y, Storme V, de Meutter J, Messens J, Lauwereys M: High-level secretion and very efficient isotopic labelling of tick anticoagulant peptide (TAP) expressed in the methylotrophic yeast, Pichia pastoris. Bio-Technology 1994, 12:1119-1124.
-
(1994)
Bio-Technology
, vol.12
, pp. 1119-1124
-
-
Laroche, Y.1
Storme, V.2
De Meutter, J.3
Messens, J.4
Lauwereys, M.5
-
16
-
-
0030220875
-
Production and isolation of the recombinant N-lobe of human serum transferrin from the methylotrophic yeast Pichia pastoris
-
Mason AB, Woodworth RC, Oliver RWA, Green BN, Lin L-N, Brandts JF, Tam BM, Maxwell A, MacGillivray RTA: Production and isolation of the recombinant N-lobe of human serum transferrin from the methylotrophic yeast Pichia pastoris. Protein Expr Purif 1996, 8:119-125.
-
(1996)
Protein Expr Purif
, vol.8
, pp. 119-125
-
-
Mason, A.B.1
Woodworth, R.C.2
Oliver, R.W.A.3
Green, B.N.4
Lin, L.-N.5
Brandts, J.F.6
Tam, B.M.7
Maxwell, A.8
MacGillivray, R.T.A.9
-
17
-
-
0030250768
-
Overexpression in Pichia pastoris and crystallization of an elicitor protein secreted by the phytopathogenic fungus, Phytophora cryptogea
-
O'Donohue MJ, Boissy G, Huet J-C, Nespoulous C, Brunie S, Pernollet J-C: Overexpression in Pichia pastoris and crystallization of an elicitor protein secreted by the phytopathogenic fungus, Phytophora cryptogea. Protein Expr Purif 1996, 8:254-261. This study presents a convincing example of the high-yield secretion of an interesting protein obtained in crystallization quality. Former approaches to produce this protein in an appropriate quality in an E. coli host had failed.
-
(1996)
Protein Expr Purif
, vol.8
, pp. 254-261
-
-
O'Donohue, M.J.1
Boissy, G.2
Huet, J.-C.3
Nespoulous, C.4
Brunie, S.5
Pernollet, J.-C.6
-
18
-
-
0030022151
-
Biochemical characterization of the recombinant Boophilus microplus Bm86 antigen expressed by transformed Pichia pastoris cells
-
Montesino R, Cremata J, Rodriguez M, Besada V, Falcón V, de la Fuente J: Biochemical characterization of the recombinant Boophilus microplus Bm86 antigen expressed by transformed Pichia pastoris cells. Biotechnol Appl Biochem 1996, 23:23-28.
-
(1996)
Biotechnol Appl Biochem
, vol.23
, pp. 23-28
-
-
Montesino, R.1
Cremata, J.2
Rodriguez, M.3
Besada, V.4
Falcón, V.5
De La Fuente, J.6
-
19
-
-
0343329802
-
Large-scale production in Pichia pastoris of the recombinant vaccine Gavac against cattle tick
-
Canales M, Enriquez A, Ramos E, Cabrera D, Dandie H, Soto A, Falcon V, Rodriguez M, de la Fuente J: Large-scale production in Pichia pastoris of the recombinant vaccine Gavac against cattle tick. Vaccine 1997, 4:414-422.
-
(1997)
Vaccine
, vol.4
, pp. 414-422
-
-
Canales, M.1
Enriquez, A.2
Ramos, E.3
Cabrera, D.4
Dandie, H.5
Soto, A.6
Falcon, V.7
Rodriguez, M.8
De La Fuente, J.9
-
20
-
-
0030475733
-
Production and purification of recombinant hirudin expressed in the methylotrophic yeast Pichia pastoris
-
Rosenfeld SA, Nadeau D, Tirado J, Hollis GF, Knabb RM, Jia S: Production and purification of recombinant hirudin expressed in the methylotrophic yeast Pichia pastoris. Protein Expr Purif 1996, 8:476-482.
-
(1996)
Protein Expr Purif
, vol.8
, pp. 476-482
-
-
Rosenfeld, S.A.1
Nadeau, D.2
Tirado, J.3
Hollis, G.F.4
Knabb, R.M.5
Jia, S.6
-
21
-
-
0029591388
-
High-level secretion of hirudin by Hansenula polymorpha - Authentic processing of three different preprohirudins
-
Weydemann U, Keup P, Piontek M, Strasser AWM, Schweden J, Gellissen G, Janowicz ZA: High-level secretion of hirudin by Hansenula polymorpha - authentic processing of three different preprohirudins. Appl Microbiol Biotechnol 1995, 44:377-385.
-
(1995)
Appl Microbiol Biotechnol
, vol.44
, pp. 377-385
-
-
Weydemann, U.1
Keup, P.2
Piontek, M.3
Strasser, A.W.M.4
Schweden, J.5
Gellissen, G.6
Janowicz, Z.A.7
-
22
-
-
0029443619
-
Expression of a synthetic gene encoding the anticoagulant-antimetastatic protein ghilanten by the methylotrophic yeast Pichia pastoris
-
Brankamp RG, Sreekrishna K, Smith PL, Blankenship DT, Cardin AD: Expression of a synthetic gene encoding the anticoagulant-antimetastatic protein ghilanten by the methylotrophic yeast Pichia pastoris. Protein Expr Purif 1995, 6:813-820.
-
(1995)
Protein Expr Purif
, vol.6
, pp. 813-820
-
-
Brankamp, R.G.1
Sreekrishna, K.2
Smith, P.L.3
Blankenship, D.T.4
Cardin, A.D.5
-
23
-
-
0030512916
-
Production of two aprotinin variants in Hansenula polymorpha
-
Zurek C, Kubis E, Keup P, Hörlein D, Beunink J, Thömmes J, Kula M-R, Hollenberg CP, Gellissen G: Production of two aprotinin variants in Hansenula polymorpha. Process Biochem 1996, 7:679-689.
-
(1996)
Process Biochem
, vol.7
, pp. 679-689
-
-
Zurek, C.1
Kubis, E.2
Keup, P.3
Hörlein, D.4
Beunink, J.5
Thömmes, J.6
Kula, M.-R.7
Hollenberg, C.P.8
Gellissen, G.9
-
24
-
-
0029990729
-
Secretion of a variant of human single-chain urokinase-type plasminogen activator without an N-glycosylation site in the methylotrophic yeast, Pichia pastoris and characterization of the secreted product
-
Tsujikawa M, Okabayashi K, Morita M, Tanabe T: Secretion of a variant of human single-chain urokinase-type plasminogen activator without an N-glycosylation site in the methylotrophic yeast, Pichia pastoris and characterization of the secreted product Yeast 1996, 12:541-553.
-
(1996)
Yeast
, vol.12
, pp. 541-553
-
-
Tsujikawa, M.1
Okabayashi, K.2
Morita, M.3
Tanabe, T.4
-
25
-
-
0030600467
-
Secretory production of recombinant urokinase-type plasminogen activator-annexin V chimeras in Pichia pastoris
-
Okabayashi K, Tsujikawa M, Morita M, Einaga K, Tanaka K, Tanabe T, Yamanouchi K, Hirama M, Tait JF, Fujikawa K: Secretory production of recombinant urokinase-type plasminogen activator-annexin V chimeras in Pichia pastoris. Gene 1996, 177:69-76.
-
(1996)
Gene
, vol.177
, pp. 69-76
-
-
Okabayashi, K.1
Tsujikawa, M.2
Morita, M.3
Einaga, K.4
Tanaka, K.5
Tanabe, T.6
Yamanouchi, K.7
Hirama, M.8
Tait, J.F.9
Fujikawa, K.10
-
26
-
-
0028785213
-
A disruption-replacement approach for the targeted integration of foreign genes in Hansenula polymorpha
-
Agaphonov MO, Beburov MY, Ter-Avanesyan MD, Smirnov VN: A disruption-replacement approach for the targeted integration of foreign genes in Hansenula polymorpha. Yeast 1995, 11:1241-1247.
-
(1995)
Yeast
, vol.11
, pp. 1241-1247
-
-
Agaphonov, M.O.1
Beburov, M.Y.2
Ter-Avanesyan, M.D.3
Smirnov, V.N.4
-
27
-
-
0029940930
-
Foreign gene expression in Hansenula polymorpha. A system for the synthesis of small functional peptides
-
Faber KN, Westra S, Waterham HR, Keizer-Gunnink I, Harder W, Veenhuis GA: Foreign gene expression in Hansenula polymorpha. A system for the synthesis of small functional peptides. Appl Microbiol Biotechnol 1996, 45:72-79. Describes the targeting of heterologous proteins to the peroxisome. Fusion to the amino oxidase stabilizes an otherwise unstable protein.
-
(1996)
Appl Microbiol Biotechnol
, vol.45
, pp. 72-79
-
-
Faber, K.N.1
Westra, S.2
Waterham, H.R.3
Keizer-Gunnink, I.4
Harder, W.5
Veenhuis, G.A.6
-
28
-
-
0030614539
-
A bioactive designer cytokine for human hematopoietic progenitor cell expansion
-
Fischer M, Goldschmitt J, Peschel C, Brakenhoff JPG, Kallen K-J, Wollmer A, Grötzinger J, Rose-John S: A bioactive designer cytokine for human hematopoietic progenitor cell expansion. Nat Biotechnol 1997, 15:142-145. The efficient production of a fusion protein consisting of interleukin-6 and a soluble form of its receptor is described. The fusion protein turned out to be fully active at 100-1000 lower concentration than the unlinked proteins in expanding gp130-expressing human haematopoietic progenitor cells. This publication opens new approaches to treating blood cell deficiencies.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 142-145
-
-
Fischer, M.1
Goldschmitt, J.2
Peschel, C.3
Brakenhoff, J.P.G.4
Kallen, K.-J.5
Wollmer, A.6
Grötzinger, J.7
Rose-John, S.8
-
29
-
-
0029863568
-
High-yield expression and secretion of the ovine pregnancy recognition hormone interferon-tau by Pichia pastoris
-
Vanheeke G, Ott TL, Strauss A, Ammaturo D, Bazer FW: High-yield expression and secretion of the ovine pregnancy recognition hormone interferon-tau by Pichia pastoris. J Interferon Cytokine Res 1996, 16:119-126.
-
(1996)
J Interferon Cytokine Res
, vol.16
, pp. 119-126
-
-
Vanheeke, G.1
Ott, T.L.2
Strauss, A.3
Ammaturo, D.4
Bazer, F.W.5
-
30
-
-
0030591760
-
Intracellular production of a major cytomegalovirus antigenic protein in the methylotrophic yeast Pichia pastoris
-
Battista MC, Bergamini G, Campanini F, Landini MP, Ripalti A: Intracellular production of a major cytomegalovirus antigenic protein in the methylotrophic yeast Pichia pastoris. Gene 1996, 176:197-201.
-
(1996)
Gene
, vol.176
, pp. 197-201
-
-
Battista, M.C.1
Bergamini, G.2
Campanini, F.3
Landini, M.P.4
Ripalti, A.5
-
31
-
-
0029839368
-
Cloning and expression in yeast Pichia pastoris of a biologically active form of Cyn d 1, the major allergen of Bermuda grass pollen
-
Smith PM, Suphioglu C, Griffith IJ, Theriault K, Knox RB, Singh MB: Cloning and expression in yeast Pichia pastoris of a biologically active form of Cyn d 1, the major allergen of Bermuda grass pollen. J Allergy Clin Immunol 1996, 98:331-343.
-
(1996)
J Allergy Clin Immunol
, vol.98
, pp. 331-343
-
-
Smith, P.M.1
Suphioglu, C.2
Griffith, I.J.3
Theriault, K.4
Knox, R.B.5
Singh, M.B.6
-
32
-
-
0029849780
-
Isolation and expression of a cDNA encoding an Alteneria alternata Alt a 1 subunit
-
De Vouge MW, Thaker AJ, Curran IHA, Zhang L, Muradia G, Rode H, Vijai HM: Isolation and expression of a cDNA encoding an Alteneria alternata Alt a 1 subunit. Int Arch Allergy Immunol 1996, 111:385-395.
-
(1996)
Int Arch Allergy Immunol
, vol.111
, pp. 385-395
-
-
De Vouge, M.W.1
Thaker, A.J.2
Curran, I.H.A.3
Zhang, L.4
Muradia, G.5
Rode, H.6
Vijai, H.M.7
-
33
-
-
0013514028
-
Production of Fv fragment of monoclonal antibody from recombinant yeast Pichia pastoris
-
Ando K, Arunwanich P, Kai K, Shinkai M, Honda H, Kobayashi T: Production of Fv fragment of monoclonal antibody from recombinant yeast Pichia pastoris. J Chem Eng Japan 1996, 29:390-392.
-
(1996)
J Chem Eng Japan
, vol.29
, pp. 390-392
-
-
Ando, K.1
Arunwanich, P.2
Kai, K.3
Shinkai, M.4
Honda, H.5
Kobayashi, T.6
-
34
-
-
0028944846
-
Generation of rabbit monoclonal antibody fragments from a combinatorial phage display library and their production in the yeast Pichia pastoris
-
Ridder R, Schmitz R, Legay F, Gram H: Generation of rabbit monoclonal antibody fragments from a combinatorial phage display library and their production in the yeast Pichia pastoris. Bio-Technology 1995, 13:255-260.
-
(1995)
Bio-Technology
, vol.13
, pp. 255-260
-
-
Ridder, R.1
Schmitz, R.2
Legay, F.3
Gram, H.4
-
35
-
-
0029560973
-
5A serotonin receptor in the methylotrophic yeast Pichia pastoris: Pharmacological charcterization and localization
-
5A serotonin receptor in the methylotrophic yeast Pichia pastoris: pharmacological charcterization and localization. FEBS Lett 1995, 377:451-456.
-
(1995)
FEBS Lett
, vol.377
, pp. 451-456
-
-
Weiß, H.M.1
Haase, W.2
Michel, H.3
Reiländer, H.4
-
36
-
-
0030574052
-
Expression and pharmacological characterization of the human μ-opioid receptor in the methylotrophic yeast Pichia pastoris
-
Talmont F, Sidobre S, Demange P, Milon A, Emorine LJ: Expression and pharmacological characterization of the human μ-opioid receptor in the methylotrophic yeast Pichia pastoris. FEBS Lett 1996, 394:268-272.
-
(1996)
FEBS Lett
, vol.394
, pp. 268-272
-
-
Talmont, F.1
Sidobre, S.2
Demange, P.3
Milon, A.4
Emorine, L.J.5
-
37
-
-
0030974549
-
Expression of trimeric CD40 ligand in Pichia pastoris: Use of a rapid method to detect high-level expressing transformants
-
McGrew JT, Leiske D, Dell B, Klinke R, Krasts D, Wee SF, Abbott N, Armitage R, Harrington K: Expression of trimeric CD40 ligand in Pichia pastoris: use of a rapid method to detect high-level expressing transformants. Gene 1997, 187:193-200.
-
(1997)
Gene
, vol.187
, pp. 193-200
-
-
McGrew, J.T.1
Leiske, D.2
Dell, B.3
Klinke, R.4
Krasts, D.5
Wee, S.F.6
Abbott, N.7
Armitage, R.8
Harrington, K.9
-
38
-
-
0030444332
-
Expression, purification, and characterization of recombinant alpha-N-acetylgalactosaminidase produced in the yeast Pichia pastoris
-
Zhu A, Monahan C, Wang ZK, Goldstein J: Expression, purification, and characterization of recombinant alpha-N-acetylgalactosaminidase produced in the yeast Pichia pastoris. Protein Expr Purif 1996, 8:456-462.
-
(1996)
Protein Expr Purif
, vol.8
, pp. 456-462
-
-
Zhu, A.1
Monahan, C.2
Wang, Z.K.3
Goldstein, J.4
-
39
-
-
0029865393
-
Characterization of recombinant alpha-galactosidase for use in seroconversion from blood-group B to blood group O of human erythrocytes
-
Zhu A, Leng L, Monahan C, Zhang ZF, Hurst R, Lenny L, Goldstein J: Characterization of recombinant alpha-galactosidase for use in seroconversion from blood-group B to blood group O of human erythrocytes. Arch Biochem Biophys 1996, 327:324-329.
-
(1996)
Arch Biochem Biophys
, vol.327
, pp. 324-329
-
-
Zhu, A.1
Leng, L.2
Monahan, C.3
Zhang, Z.F.4
Hurst, R.5
Lenny, L.6
Goldstein, J.7
-
40
-
-
0028828190
-
High-level expression and purification of coffee bean α-galactosidase produced in the yeast Pichia pastoris
-
Zhu A, Monahan C, Zhang Z, Hurst R, Leng L, Goldstein J: High-level expression and purification of coffee bean α-galactosidase produced in the yeast Pichia pastoris. Arch Biochem Biophys 1995, 324:65-70.
-
(1995)
Arch Biochem Biophys
, vol.324
, pp. 65-70
-
-
Zhu, A.1
Monahan, C.2
Zhang, Z.3
Hurst, R.4
Leng, L.5
Goldstein, J.6
-
41
-
-
9344252854
-
Cloning, expression and characterization of a blood group B active recombinant alpha-D-galactosidase from soybean (glycine-max)
-
Davis MO, Hata DJ, Johnson SA, Walker JC, Smith DS: Cloning, expression and characterization of a blood group B active recombinant alpha-D-galactosidase from soybean (glycine-max). Biochem Mol Biol Int 1996, 39:471-485.
-
(1996)
Biochem Mol Biol int
, vol.39
, pp. 471-485
-
-
Davis, M.O.1
Hata, D.J.2
Johnson, S.A.3
Walker, J.C.4
Smith, D.S.5
-
42
-
-
0030250653
-
Overexpression, purification and characterization of recombinant barley α-amylase-1 and 2 secreted by the methylotrophic yeast Pichia pastoris
-
Juge N, Andersen JS, Tull D, Roepstorff P, Svensson B: Overexpression, purification and characterization of recombinant barley α-amylase-1 and 2 secreted by the methylotrophic yeast Pichia pastoris. Protein Expr Purif 1996, 8:204-214.
-
(1996)
Protein Expr Purif
, vol.8
, pp. 204-214
-
-
Juge, N.1
Andersen, J.S.2
Tull, D.3
Roepstorff, P.4
Svensson, B.5
-
43
-
-
0343989849
-
Biochemical responses of recombinant strains of Hansenula polymorpha on oversynthesis of homologous dihydroxyacetone kinase and bacterial β-galactosidase
-
Velkov VV, Matys VY, Solokov: Biochemical responses of recombinant strains of Hansenula polymorpha on oversynthesis of homologous dihydroxyacetone kinase and bacterial β-galactosidase. Appl Biochem Microbiol 1996, 32:100-105.
-
(1996)
Appl Biochem Microbiol
, vol.32
, pp. 100-105
-
-
Velkov, V.V.1
Matys, V.Y.2
Solokov3
-
44
-
-
0343113395
-
Expression of the major bean proteins from Theobrama cacao (Cocoa) in the yeasts Hansenula polymorpha and Saccharomyces cerevisiae
-
Yavuz MÖ, Ashton SMV, Deakin ED, Spencer ME, Sudbery PE: Expression of the major bean proteins from Theobrama cacao (Cocoa) in the yeasts Hansenula polymorpha and Saccharomyces cerevisiae. J Biotechnol 1996, 46:43-54.
-
(1996)
J Biotechnol
, vol.46
, pp. 43-54
-
-
Yavuz, M.Ö.1
Ashton, S.M.V.2
Deakin, E.D.3
Spencer, M.E.4
Sudbery, P.E.5
-
45
-
-
0029866204
-
Efficient expression of the gene for spinach phosphoribulokinase in Pichia pastoris and utilization of the recombinant enzyme to explore the role of regulatory cysteinyl residues by site-directed mutagenesis
-
Brandes HK, Hartman FC, Lu TYS, Larimer FW: Efficient expression of the gene for spinach phosphoribulokinase in Pichia pastoris and utilization of the recombinant enzyme to explore the role of regulatory cysteinyl residues by site-directed mutagenesis. J Biol Chem 1996, 271:6490-6496.
-
(1996)
J Biol Chem
, vol.271
, pp. 6490-6496
-
-
Brandes, H.K.1
Hartman, F.C.2
Lu, T.Y.S.3
Larimer, F.W.4
-
46
-
-
0029595212
-
High-level production of spinach glycolate oxidase in the methylotrophix yeast Pichia pastoris - Engineering a biocatalyst
-
Payne MS, Petrillo KL, Gavagan JE, Wagner LW, DiCosimo R, Anton DL: High-level production of spinach glycolate oxidase in the methylotrophix yeast Pichia pastoris - engineering a biocatalyst Gene 1995, 167:215-219.
-
(1995)
Gene
, vol.167
, pp. 215-219
-
-
Payne, M.S.1
Petrillo, K.L.2
Gavagan, J.E.3
Wagner, L.W.4
DiCosimo, R.5
Anton, D.L.6
-
47
-
-
0029813916
-
Recombinant Hansenula polymorpha as a biocatalyst: Coexpression of the spinach glycolate oxidase (GO) and the S. cerevisiae catalase T (CTT1) gene
-
Gellissen G, Piontek M, Dahlems U, Jenzelewski V, Gavagan JE, DiCosimo R, Anton DL, Janowicz ZA: Recombinant Hansenula polymorpha as a biocatalyst: coexpression of the spinach glycolate oxidase (GO) and the S. cerevisiae catalase T (CTT1) gene. Appl Microbiol Biotechnol 1996, 46:46-54. Two enzyme genes are integrated in anticipated fixed copy number ratios. A recombinant peroxisomal and a cytoplasmic enzyme are co-produced. This is a strategy to use recombinant H. polymorpha strains as biocatalyst.
-
(1996)
Appl Microbiol Biotechnol
, vol.46
, pp. 46-54
-
-
Gellissen, G.1
Piontek, M.2
Dahlems, U.3
Jenzelewski, V.4
Gavagan, J.E.5
Dicosimo, R.6
Anton, D.L.7
Janowicz, Z.A.8
-
48
-
-
0028589448
-
Increase in copy number of an integrated vector during continuous culture of Hansenula polymorpha expressing functional hemoglobin
-
Gilbert SC, van Urk H, Greefield DM, McAvoy MJ, Denton KA, Coghlan D, Jones GD, Mead DJ: Increase in copy number of an integrated vector during continuous culture of Hansenula polymorpha expressing functional hemoglobin. Yeast 1994, 10:1569-1580.
-
(1994)
Yeast
, vol.10
, pp. 1569-1580
-
-
Gilbert, S.C.1
Van Urk, H.2
Greefield, D.M.3
McAvoy, M.J.4
Denton, K.A.5
Coghlan, D.6
Jones, G.D.7
Mead, D.J.8
-
49
-
-
0029829267
-
The methylotrophic yeast Pichia pastoris synthesizes a functionally active chromophore precursor of the plant photoreceptor phytochrome
-
Wu S-H, Lagarias JC: The methylotrophic yeast Pichia pastoris synthesizes a functionally active chromophore precursor of the plant photoreceptor phytochrome. Proc Natl Acad Sci USA 1996, 93:8989-8994.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8989-8994
-
-
Wu, S.-H.1
Lagarias, J.C.2
-
50
-
-
0029790768
-
Drosophila melanogaster angiotensin-l-converting enzyme expressed in Pichia pastoris resembles the C-domain of the mammalian homolog and does not require glycosylation for secretion and enzymatic activity
-
Williams TA, Michaud A, Houard X, Chauvet MT, Soubrier F, Corvol P: Drosophila melanogaster angiotensin-l-converting enzyme expressed in Pichia pastoris resembles the C-domain of the mammalian homolog and does not require glycosylation for secretion and enzymatic activity. Biochem J 1996, 318:125-131.
-
(1996)
Biochem J
, vol.318
, pp. 125-131
-
-
Williams, T.A.1
Michaud, A.2
Houard, X.3
Chauvet, M.T.4
Soubrier, F.5
Corvol, P.6
-
51
-
-
0030040517
-
Production of a recombinant bovine enterokinase catalytic subunit in the methylotrophic yeast Pichia pastoris
-
Vozza LA, Wittwer L, Higgins DR, Purcell TJ, Bergseid M, Collinsracie LA, Lavallie ER, Hoeffler JP: Production of a recombinant bovine enterokinase catalytic subunit in the methylotrophic yeast Pichia pastoris. Bio-Technology 1996, 14:77-81.
-
(1996)
Bio-Technology
, vol.14
, pp. 77-81
-
-
Vozza, L.A.1
Wittwer, L.2
Higgins, D.R.3
Purcell, T.J.4
Bergseid, M.5
Collinsracie, L.A.6
Lavallie, E.R.7
Hoeffler, J.P.8
-
52
-
-
0000296246
-
Hansenula polymorpha (Pichia angusta)
-
Edited by Wolf K. Heidelberg: Springer
-
Hansen H, Hollenberg CP: Hansenula polymorpha (Pichia angusta). In Nonconventional Yeasts in Biotechnology. Edited by Wolf K. Heidelberg: Springer; 1996:293-311.
-
(1996)
Nonconventional Yeasts in Biotechnology
, pp. 293-311
-
-
Hansen, H.1
Hollenberg, C.P.2
-
54
-
-
0030997654
-
Strategies for optimal synthesis and secretion of heterologous proteins in the methylotrophic yeast Pichia pastoris
-
Sreekrishna K, Brankamp RG, Kropp KE, Blankenship DT, Tsay J-T, Smith PL, Wierschke JD, Subramaniam A, Birkenberger LA: Strategies for optimal synthesis and secretion of heterologous proteins in the methylotrophic yeast Pichia pastoris. Gene 1997, 190:55-62.
-
(1997)
Gene
, vol.190
, pp. 55-62
-
-
Sreekrishna, K.1
Brankamp, R.G.2
Kropp, K.E.3
Blankenship, D.T.4
Tsay, J.-T.5
Smith, P.L.6
Wierschke, J.D.7
Subramaniam, A.8
Birkenberger, L.A.9
-
55
-
-
0029743974
-
A novel autonomously replicating sequence (ARS) for multiple integration in the yeast Hansenula polymorpha DL1
-
Sohn JH, Choi ES, Kim CH, Agaphonov MO, Ter-Avanesyan MD, Rhee JS, Rhee SK: A novel autonomously replicating sequence (ARS) for multiple integration in the yeast Hansenula polymorpha DL1. J Bacteriol 1996, 178:4420-4428.
-
(1996)
J Bacteriol
, vol.178
, pp. 4420-4428
-
-
Sohn, J.H.1
Choi, E.S.2
Kim, C.H.3
Agaphonov, M.O.4
Ter-Avanesyan, M.D.5
Rhee, J.S.6
Rhee, S.K.7
-
57
-
-
0028868957
-
Stable multicopy integration of vector sequences in Hanseula polymorpha
-
Gatzke R, Weydemann U, Janowicz ZA, Hollenberg CP: Stable multicopy integration of vector sequences in Hanseula polymorpha. Appl Microbiol Biotechnol 1995, 43:844-849.
-
(1995)
Appl Microbiol Biotechnol
, vol.43
, pp. 844-849
-
-
Gatzke, R.1
Weydemann, U.2
Janowicz, Z.A.3
Hollenberg, C.P.4
-
58
-
-
0028940737
-
Plasmid reorganization during integrative transformation in Hansenula polymorpha
-
Bogdanova AI, Agaphonov MO, Ter-Avanesyan MD: Plasmid reorganization during integrative transformation in Hansenula polymorpha. Yeast 1995, 11:343-353.
-
(1995)
Yeast
, vol.11
, pp. 343-353
-
-
Bogdanova, A.I.1
Agaphonov, M.O.2
Ter-Avanesyan, M.D.3
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