Total biosynthesis of hydrocortisone from a simple carbon source in yeast

Nature Biotechnology

Volumn 21, Issue 2, 2003, Pages 143-149

  Szczebara, Florence Ménard ^a,b   Chandelier, Cathy ^a,c   Villeret, Coralie ^a   Masurel, Amélie ^a   Bourot, Stéphane ^a,c   Duport, Catherine ^a,d   Blanchard, Sophie ^e,f   Groisillier, Agnès ^e,g   Testet, Eric ^e   Costaglioli, Patricia ^e   Cauet, Gilles ^h   Degryse, Eric ^h,i   Balbuena, David ^j   Winter, Jacques ^j,k   Achstetter, Tilman ^e,h,l   Spagnoli, Roberto ^j   Pompon, Denis ^a   Dumas, Bruno ^j  

^a CNRS   (France)

^b Anjou Recherche   (France)

^c BAYER AG   (Germany)

^d UMR A 408 INRA University of Avignon   (France)

^e UNIVERSITÉ DE BORDEAUX   (France)

^f UNIVERSITÉ DE PAU ET DES PAYS DE L'ADOUR   (France)

^g STATION BIOLOGIQUE   (France)

^h TRANSGENE S A   (France)

ⁱ Pernod Ricard   (France)

^j SANOFI   (France)

^k Infors Sarl   (France)

^l HOCHSCHULE BREMEN   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; DRUG PRODUCTS; GENES; PROTEINS; SUBSTRATES; YEAST;

MAMMALS;

BIOTECHNOLOGY;

ADRENODOXIN; CYTOCHROME P450; CYTOCHROME P450 11A1; CYTOCHROME P450 11B1; CYTOCHROME P450 17; CYTOCHROME P450 17A1; CYTOCHROME P450 21A1; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; HYDROCORTISONE; UNCLASSIFIED DRUG;

ARTICLE; CARBON SOURCE; DRUG SYNTHESIS; ENZYME SUBSTRATE; EUKARYOTE; FEASIBILITY STUDY; GENE EXPRESSION; GENETIC ENGINEERING AND GENE TECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ANIMALS; CARBON; CATTLE; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; ETHANOL; GENE EXPRESSION REGULATION, FUNGAL; GENETIC ENGINEERING; GLUCOSE; HUMANS; HYDROCORTISONE; MULTIENZYME COMPLEXES; QUALITY CONTROL; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SPECIES SPECIFICITY;

EUKARYOTA; MAMMALIA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0037313962     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt775     Document Type: Article

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