-
2
-
-
0035843170
-
Industrial biocatalysis today and tomorrow
-
This review presents an excellent overview of the current status and the emerging frontiers in biocatalysis from an industrial perspective.
-
Schmid A., Dordick J.S., Hauer B., Kiener A., Wubbolts M., Witholt B. Industrial biocatalysis today and tomorrow. Nature. 409:2001;258-268 This review presents an excellent overview of the current status and the emerging frontiers in biocatalysis from an industrial perspective.
-
(2001)
Nature
, vol.409
, pp. 258-268
-
-
Schmid, A.1
Dordick, J.S.2
Hauer, B.3
Kiener, A.4
Wubbolts, M.5
Witholt, B.6
-
3
-
-
0035843122
-
Enzymes for chemical synthesis
-
Koeller K.M., Wong C.H. Enzymes for chemical synthesis. Nature. 409:2001;232-240.
-
(2001)
Nature
, vol.409
, pp. 232-240
-
-
Koeller, K.M.1
Wong, C.H.2
-
4
-
-
0036536478
-
Directed evolution of enzymes and pathways for industrial biocatalysis
-
Zhao H., Chockalingam K., Chen Z. Directed evolution of enzymes and pathways for industrial biocatalysis. Curr Opin Biotechnol. 13:2002;104-110.
-
(2002)
Curr Opin Biotechnol
, vol.13
, pp. 104-110
-
-
Zhao, H.1
Chockalingam, K.2
Chen, Z.3
-
5
-
-
0035313656
-
Dehydrogenases and transaminases in asymmetric synthesis
-
Stewart J.D. Dehydrogenases and transaminases in asymmetric synthesis. Curr Opin Chem Biol. 5:2001;120-129.
-
(2001)
Curr Opin Chem Biol
, vol.5
, pp. 120-129
-
-
Stewart, J.D.1
-
6
-
-
0036525715
-
Oxidative biotransformations using oxygenases
-
Li Z., van Beilen J.B., Duetz W.A., Schmid A., de Raadt A., Griengl H., Witholt B. Oxidative biotransformations using oxygenases. Curr Opin Chem Biol. 6:2002;136-144.
-
(2002)
Curr Opin Chem Biol
, vol.6
, pp. 136-144
-
-
Li, Z.1
Van Beilen, J.B.2
Duetz, W.A.3
Schmid, A.4
De Raadt, A.5
Griengl, H.6
Witholt, B.7
-
8
-
-
0035041719
-
Redox enzymes used in chiral syntheses coupled to coenzyme regeneration
-
Leonida M.D. Redox enzymes used in chiral syntheses coupled to coenzyme regeneration. Curr Med Chem. 8:2001;345-369.
-
(2001)
Curr Med Chem
, vol.8
, pp. 345-369
-
-
Leonida, M.D.1
-
9
-
-
0345817539
-
Regeneration of nicotinamide cofactors for use in organic synthesis
-
Chenault H.K., Whitesides G.M. Regeneration of nicotinamide cofactors for use in organic synthesis. Appl Biochem Biotechnol. 14:1987;147-197.
-
(1987)
Appl Biochem Biotechnol
, vol.14
, pp. 147-197
-
-
Chenault, H.K.1
Whitesides, G.M.2
-
10
-
-
0031104963
-
Potential applications of NAD(P)-dependent oxidoreductases in synthesis - A survey
-
Devaux-Basséguy R., Bergel A., Comtat M. Potential applications of NAD(P)-dependent oxidoreductases in synthesis - a survey. Enzyme Microb Technol. 20:1997;248-258.
-
(1997)
Enzyme Microb Technol
, vol.20
, pp. 248-258
-
-
Devaux-Basséguy, R.1
Bergel, A.2
Comtat, M.3
-
11
-
-
0033485581
-
Large-scale applications of NAD(P)-dependent oxidoreductases: Recent developments
-
Hummel W. Large-scale applications of NAD(P)-dependent oxidoreductases: recent developments. Trends Biotechnol. 17:1999;487-492.
-
(1999)
Trends Biotechnol
, vol.17
, pp. 487-492
-
-
Hummel, W.1
-
12
-
-
0037084327
-
Highly enantioselective preparation of multifunctionalized propargylic building blocks
-
Schubert T., Hummel W., Muller M. Highly enantioselective preparation of multifunctionalized propargylic building blocks. Angew Chem Int Ed Engl. 41:2002;634-637.
-
(2002)
Angew Chem Int Ed Engl
, vol.41
, pp. 634-637
-
-
Schubert, T.1
Hummel, W.2
Muller, M.3
-
13
-
-
0034677110
-
Cofactor-bound cross-linked enzyme crystals (CLEC) of alcohol dehydrogenase
-
This paper describes the use of CLECs to stabilize both the dehydrogenase enzyme and the cofactor in a nicotinamide cofactor regeneration system.
-
St Clair N., Wang Y.F., Margolin A.L. Cofactor-bound cross-linked enzyme crystals (CLEC) of alcohol dehydrogenase. Angew Chem Int Ed Engl. 39:2000;380-383 This paper describes the use of CLECs to stabilize both the dehydrogenase enzyme and the cofactor in a nicotinamide cofactor regeneration system.
-
(2000)
Angew Chem Int Ed Engl
, vol.39
, pp. 380-383
-
-
St Clair, N.1
Wang, Y.F.2
Margolin, A.L.3
-
14
-
-
0035689388
-
Two-enzyme cross-linked crystals for chiral synthesis coupled with electroenzymatic regeneration of the cofactor
-
Leonida M.D., Fry A.J., Sobolov S.B., Bartoszko-Malik A. Two-enzyme cross-linked crystals for chiral synthesis coupled with electroenzymatic regeneration of the cofactor. Intl J Biochromat. 6:2001;207-217.
-
(2001)
Intl J Biochromat
, vol.6
, pp. 207-217
-
-
Leonida, M.D.1
Fry, A.J.2
Sobolov, S.B.3
Bartoszko-Malik, A.4
-
15
-
-
84907037937
-
Some new developments in reductive amination with cofactor regeneration
-
Bommarius A.S., Drauz K., Hummel W., Kula M.R., Wandrey C. Some new developments in reductive amination with cofactor regeneration. Biocatalysis. 10:1994;37-47.
-
(1994)
Biocatalysis
, vol.10
, pp. 37-47
-
-
Bommarius, A.S.1
Drauz, K.2
Hummel, W.3
Kula, M.R.4
Wandrey, C.5
-
16
-
-
0032530505
-
Biocatalysis to amino acid-based chiral pharmaceuticals - Examples and perspectives
-
Bommarius A.S., Schwarm M., Drauz K. Biocatalysis to amino acid-based chiral pharmaceuticals - examples and perspectives. J Mol Catal B Enzym. 5:1998;1-11.
-
(1998)
J Mol Catal B Enzym
, vol.5
, pp. 1-11
-
-
Bommarius, A.S.1
Schwarm, M.2
Drauz, K.3
-
17
-
-
0034011107
-
Stabilization of NAD-dependent formate dehydrogenase from Candida boidinii by site-directed mutagenesis of cysteine residues
-
Slusarczyk H., Felber S., Kula M.-R., Pohl M. Stabilization of NAD-dependent formate dehydrogenase from Candida boidinii by site-directed mutagenesis of cysteine residues. Eur J Biochem. 267:2000;1280-1289.
-
(2000)
Eur J Biochem
, vol.267
, pp. 1280-1289
-
-
Slusarczyk, H.1
Felber, S.2
Kula, M.-R.3
Pohl, M.4
-
18
-
-
0030312717
-
Cofactor regeneration in biocatalysis in organic media
-
Adlercreutz P. Cofactor regeneration in biocatalysis in organic media. Biocat Biotransform. 14:1996;1-30.
-
(1996)
Biocat Biotransform
, vol.14
, pp. 1-30
-
-
Adlercreutz, P.1
-
19
-
-
0037666071
-
Practical asymmetric enzymatic reduction through discovery of a dehydrogenase-compatible biphasic reaction media
-
Groeger H., Hummel W., Buchholz S., Drauz K., Nguyen T.V., Rollmann C., Huesken H., Abokitse K. Practical asymmetric enzymatic reduction through discovery of a dehydrogenase-compatible biphasic reaction media. Org Lett. 5:2003;173-176.
-
(2003)
Org Lett
, vol.5
, pp. 173-176
-
-
Groeger, H.1
Hummel, W.2
Buchholz, S.3
Drauz, K.4
Nguyen, T.V.5
Rollmann, C.6
Huesken, H.7
Abokitse, K.8
-
20
-
-
0035931416
-
Preparative regio- and chemoselective functionalization of hydrocarbons catalyzed by cell-free preparations of 2-hydroxybiphenyl 3-monooxygenase
-
Schmid A., Vereyken I., Held M., Witholt B. Preparative regio- and chemoselective functionalization of hydrocarbons catalyzed by cell-free preparations of 2-hydroxybiphenyl 3-monooxygenase. J Mol Catal B Enzym. 11:2001;455-462.
-
(2001)
J Mol Catal B Enzym
, vol.11
, pp. 455-462
-
-
Schmid, A.1
Vereyken, I.2
Held, M.3
Witholt, B.4
-
22
-
-
0035907326
-
Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88
-
Costas A.M., White A.K., Metcalf W.W. Purification and characterization of a novel phosphorus-oxidizing enzyme from Pseudomonas stutzeri WM88. J Biol Chem. 276:2001;17429-17436.
-
(2001)
J Biol Chem
, vol.276
, pp. 17429-17436
-
-
Costas, A.M.1
White, A.K.2
Metcalf, W.W.3
-
23
-
-
0037008984
-
Phosphite dehydrogenase, a new versatile cofactor regeneration enzyme
-
This study presents a new method for regenerating reduced nicotinamide cofactors based on a recently discovered enzyme, phosphite dehydrogenase. Because of the intrinsic large thermodynamic driving force, the innocuous nature of phosphite and phosphate to the enzymes, and the low cost of phosphite, this phosphite-phosphite dehydrogenase system may prove complementary to the most widely used formate-formate dehydrogenase system.
-
Vrtis J.M., White A., Metcalf W.W., van der Donk W.A. Phosphite dehydrogenase, a new versatile cofactor regeneration enzyme. Angew Chem Int Ed Engl. 41:2002;3257-3259 This study presents a new method for regenerating reduced nicotinamide cofactors based on a recently discovered enzyme, phosphite dehydrogenase. Because of the intrinsic large thermodynamic driving force, the innocuous nature of phosphite and phosphate to the enzymes, and the low cost of phosphite, this phosphite-phosphite dehydrogenase system may prove complementary to the most widely used formate-formate dehydrogenase system.
-
(2002)
Angew Chem Int Ed Engl
, vol.41
, pp. 3257-3259
-
-
Vrtis, J.M.1
White, A.2
Metcalf, W.W.3
Van der Donk, W.A.4
-
25
-
-
0034466694
-
Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone
-
This article describes the use of an STH from Pseudomonas fluorescens for the regeneration of the nicotinamide cofactors NAD and NADP in the synthesis of hydromorphone in both cell-free and whole-cell systems. STH can transfer reducing equivalents between NAD(H) and NADP(H).
-
Boonstra B., Rathbone D.A., French C.E., Walker E.H., Bruce N.C. Cofactor regeneration by a soluble pyridine nucleotide transhydrogenase for biological production of hydromorphone. Appl Environ Microbiol. 66:2000;5161-5166 This article describes the use of an STH from Pseudomonas fluorescens for the regeneration of the nicotinamide cofactors NAD and NADP in the synthesis of hydromorphone in both cell-free and whole-cell systems. STH can transfer reducing equivalents between NAD(H) and NADP(H).
-
(2000)
Appl Environ Microbiol
, vol.66
, pp. 5161-5166
-
-
Boonstra, B.1
Rathbone, D.A.2
French, C.E.3
Walker, E.H.4
Bruce, N.C.5
-
26
-
-
85005697480
-
Dehydrogenases for the synthesis of chiral compounds
-
Hummel W., Kula M.R. Dehydrogenases for the synthesis of chiral compounds. Eur J Biochem. 184:1989;1-13.
-
(1989)
Eur J Biochem
, vol.184
, pp. 1-13
-
-
Hummel, W.1
Kula, M.R.2
-
28
-
-
0037415359
-
NADH oxidase from Lactobacillus brevis: A new catalyst for the regeneration of NAD
-
+ from NADH in which the NADH oxidase was coupled with an NAD-dependent ADH to produce enantiomerically pure alcohol from a racemic mixture.
-
+ from NADH in which the NADH oxidase was coupled with an NAD-dependent ADH to produce enantiomerically pure alcohol from a racemic mixture.
-
(2003)
Enzyme Microb Technol
, vol.32
, pp. 205-211
-
-
Geueke, B.1
Riebel, B.2
Hummel, W.3
-
29
-
-
0034792157
-
Structural, redox, and mechanistic parameters for cysteine-sulfenic acid function in catalysis and regulation
-
Claiborne A., Mallett T.C., Yeh J.I., Luba J., Parsonage D. Structural, redox, and mechanistic parameters for cysteine-sulfenic acid function in catalysis and regulation. Adv Protein Chem. 58:2001;215-276.
-
(2001)
Adv Protein Chem
, vol.58
, pp. 215-276
-
-
Claiborne, A.1
Mallett, T.C.2
Yeh, J.I.3
Luba, J.4
Parsonage, D.5
-
30
-
-
0035471221
-
Surface-modified electrodes for NADH oxidation in oxidoreductase-catalysed synthesis
-
Délécouls-Servat K., Bergel A., Basséguy R. Surface-modified electrodes for NADH oxidation in oxidoreductase-catalysed synthesis. J Appl Electrochem. 31:2001;1095-1101.
-
(2001)
J Appl Electrochem
, vol.31
, pp. 1095-1101
-
-
Délécouls-Servat, K.1
Bergel, A.2
Basséguy, R.3
-
33
-
-
0346668121
-
Membrane electrochemical reactor (MER): Application to NADH regeneration for ADH-catalysed synthesis
-
Délécouls-Servat K., Basséguy R., Bergel A. Membrane electrochemical reactor (MER): application to NADH regeneration for ADH-catalysed synthesis. Chem Engin Sci. 57:2002;4633-4642.
-
(2002)
Chem Engin Sci
, vol.57
, pp. 4633-4642
-
-
Délécouls-Servat, K.1
Basséguy, R.2
Bergel, A.3
-
34
-
-
33748225950
-
Formate-driven, nonenzymic NAD(P)H regeneration in the alcohol dehydrogenase-catalyzed stereoselective reduction of 4-phenyl-2-butanone
-
Westerhausen D., Herrmann S., Hummel W., Steckhan E. Formate-driven, nonenzymic NAD(P)H regeneration in the alcohol dehydrogenase-catalyzed stereoselective reduction of 4-phenyl-2-butanone. Angew Chem Int Ed Engl. 31:1992;1529-1531.
-
(1992)
Angew Chem Int Ed Engl
, vol.31
, pp. 1529-1531
-
-
Westerhausen, D.1
Herrmann, S.2
Hummel, W.3
Steckhan, E.4
-
35
-
-
0035825143
-
The first synthetic application of a monooxygenase employing indirect electrochemical NADH regeneration
-
2+ for cofactor regeneration with monooxygenases. This Rh complex exhibits high stability and activity over a broad range of pH and temperature. Moreover, both cheap electrical power and chemicals such as formate or alcohols can be used as the source of reducing equivalents. Compared with other in vitro enzymatic cofactor regeneration systems, the turnover numbers of this method are somewhat lower.
-
2+ for cofactor regeneration with monooxygenases. This Rh complex exhibits high stability and activity over a broad range of pH and temperature. Moreover, both cheap electrical power and chemicals such as formate or alcohols can be used as the source of reducing equivalents. Compared with other in vitro enzymatic cofactor regeneration systems, the turnover numbers of this method are somewhat lower.
-
(2001)
Angew Chem Int Ed Engl
, vol.40
, pp. 169-171
-
-
Hollmann, F.1
Schmid, A.2
Steckhan, E.3
-
36
-
-
0037010696
-
Preparative application of 2-hydroxybiphenyl 3-monooxygenase with enzymatic cofactor regeneration in organic-aqueous reaction media
-
Lutz J., Mozhaev V.V., Khmelnitsky Y.L., Witholt B., Schmid A. Preparative application of 2-hydroxybiphenyl 3-monooxygenase with enzymatic cofactor regeneration in organic-aqueous reaction media. J Mol Catal B Enzym. 19:2002;177-187.
-
(2002)
J Mol Catal B Enzym
, vol.19
, pp. 177-187
-
-
Lutz, J.1
Mozhaev, V.V.2
Khmelnitsky, Y.L.3
Witholt, B.4
Schmid, A.5
-
37
-
-
0035904986
-
+: Structure-activity relationships, kinetics, and mechanistic aspects in the formation of the 1,4-NADH derivatives
-
+: structure-activity relationships, kinetics, and mechanistic aspects in the formation of the 1,4-NADH derivatives. Inorg Chem. 40:2001;6705-6716.
-
(2001)
Inorg Chem
, vol.40
, pp. 6705-6716
-
-
Lo, H.C.1
Leiva, C.2
Buriez, O.3
Kerr, J.B.4
Olmstead, M.M.5
Fish, R.H.6
-
38
-
-
10044271107
-
2+: A versatile tool for efficient and non-enzymatic regeneration of nicotinamide and flavin coenzymes
-
2+: a versatile tool for efficient and non-enzymatic regeneration of nicotinamide and flavin coenzymes. J Mol Catal B Enzym. 19:2002;167-176.
-
(2002)
J Mol Catal B Enzym
, vol.19
, pp. 167-176
-
-
Hollmann, F.1
Witholt, B.2
Schmid, A.3
-
40
-
-
0030738089
-
Synthesis of chiral ε-lactones in a two-enzyme system of cyclohexanone mono-oxygenase and formate dehydrogenase with integrated bubble-free aeration
-
Rissom S., Schwarz-Linek U., Vogel M., Tishkov V.I., Kragl U. Synthesis of chiral ε-lactones in a two-enzyme system of cyclohexanone mono-oxygenase and formate dehydrogenase with integrated bubble-free aeration. Tetrahedron Asymmetry. 8:1997;2523-2526.
-
(1997)
Tetrahedron Asymmetry
, vol.8
, pp. 2523-2526
-
-
Rissom, S.1
Schwarz-Linek, U.2
Vogel, M.3
Tishkov, V.I.4
Kragl, U.5
-
41
-
-
0343832155
-
Synthesis of natural product precursors by Baeyer-Villiger oxidation with cyclohexanone monooxygenase from Acinetobacter
-
Schwarz-Linek U, Krodel A, Ludwig FA, Schulze A, Rissom S, Kragl U, Tishkov VI, Vogel M: Synthesis of natural product precursors by Baeyer-Villiger oxidation with cyclohexanone monooxygenase from Acinetobacter. Synthesis 2001:947-951.
-
(2001)
Synthesis
, pp. 947-951
-
-
Schwarz-Linek, U.1
Krodel, A.2
Ludwig, F.A.3
Schulze, A.4
Rissom, S.5
Kragl, U.6
Tishkov, V.I.7
Vogel, M.8
-
42
-
-
0035923612
-
Taxol biosynthesis: Taxane 13 α-hydroxylase is a cytochrome P450-dependent monooxygenase
-
Jennewein S., Rithner C.D., Williams R.M., Croteau R.B. Taxol biosynthesis: Taxane 13 α-hydroxylase is a cytochrome P450-dependent monooxygenase. Proc Natl Acad Sci USA. 98:2001;13595-13600.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 13595-13600
-
-
Jennewein, S.1
Rithner, C.D.2
Williams, R.M.3
Croteau, R.B.4
-
43
-
-
0037023928
-
Use of isolated cyclohexanone monooxygenase from recombinant Escherichia coli as a biocatalyst for Baeyer-Villiger and sulfide oxidations
-
Zambianchi F., Pasta P., Carrea G., Colonna S., Gaggero N., Woodley J.M. Use of isolated cyclohexanone monooxygenase from recombinant Escherichia coli as a biocatalyst for Baeyer-Villiger and sulfide oxidations. Biotechnol Bioeng. 78:2002;489-496.
-
(2002)
Biotechnol Bioeng
, vol.78
, pp. 489-496
-
-
Zambianchi, F.1
Pasta, P.2
Carrea, G.3
Colonna, S.4
Gaggero, N.5
Woodley, J.M.6
-
45
-
-
0041404265
-
Microbial conversion with cofactor regeneration using genetically engineered bacteria
-
Endo T., Koizumi S. Microbial conversion with cofactor regeneration using genetically engineered bacteria. Adv Synth Cat. 343:2001;521-526.
-
(2001)
Adv Synth Cat
, vol.343
, pp. 521-526
-
-
Endo, T.1
Koizumi, S.2
-
46
-
-
0035424201
-
Using proteins in their natural environment: Potential and limitations of microbial whole-cell hydroxylations in applied biocatalysis
-
This review gives an excellent overview of the field of whole-cell catalysis for hydroxylation reactions.
-
Duetz W.A., van Beilen J.B., Witholt B. Using proteins in their natural environment: potential and limitations of microbial whole-cell hydroxylations in applied biocatalysis. Curr Opin Biotechnol. 12:2001;419-425 This review gives an excellent overview of the field of whole-cell catalysis for hydroxylation reactions.
-
(2001)
Curr Opin Biotechnol
, vol.12
, pp. 419-425
-
-
Duetz, W.A.1
Van Beilen, J.B.2
Witholt, B.3
-
47
-
-
0032951737
-
Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by Escherichia coli transformant cells coexpressing the aldehyde reductase and glucose dehydrogenase genes
-
Kataoka M., Yamamoto K., Kawabata H., Wada M., Kita K., Yanase H., Shimizu S. Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by Escherichia coli transformant cells coexpressing the aldehyde reductase and glucose dehydrogenase genes. Appl Microbiol Biotechnol. 51:1999;486-490.
-
(1999)
Appl Microbiol Biotechnol
, vol.51
, pp. 486-490
-
-
Kataoka, M.1
Yamamoto, K.2
Kawabata, H.3
Wada, M.4
Kita, K.5
Yanase, H.6
Shimizu, S.7
-
48
-
-
0037087669
-
Biocatalytic asymmetric hydrogen transfer
-
This paper reports the first-time use of lyophilized whole cells of Rhodococcus ruber DSM 44541 to produce secondary alcohols using acetone as a cosubstrate.
-
Stampfer W., Kosjek B., Moitzi C., Kroutil W., Faber K. Biocatalytic asymmetric hydrogen transfer. Angew Chem Int Ed Engl. 41:2002;1014-1017 This paper reports the first-time use of lyophilized whole cells of Rhodococcus ruber DSM 44541 to produce secondary alcohols using acetone as a cosubstrate.
-
(2002)
Angew Chem Int Ed Engl
, vol.41
, pp. 1014-1017
-
-
Stampfer, W.1
Kosjek, B.2
Moitzi, C.3
Kroutil, W.4
Faber, K.5
-
49
-
-
0037473197
-
On the organic solvent and thermostability of the biocatalytic redox system of Rhodococcus ruber DSM 44541
-
Stampfer W., Kosjek B., Kroutil W., Faber K. On the organic solvent and thermostability of the biocatalytic redox system of Rhodococcus ruber DSM 44541. Biotechnol Bioeng. 81:2003;865-869.
-
(2003)
Biotechnol Bioeng
, vol.81
, pp. 865-869
-
-
Stampfer, W.1
Kosjek, B.2
Kroutil, W.3
Faber, K.4
-
50
-
-
0036093463
-
Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH
-
Itoh N., Matsuda M., Mabuchi M., Dairi T., Wang J. Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH. Eur J Biochem. 269:2002;2394-2402.
-
(2002)
Eur J Biochem
, vol.269
, pp. 2394-2402
-
-
Itoh, N.1
Matsuda, M.2
Mabuchi, M.3
Dairi, T.4
Wang, J.5
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