-
1
-
-
34848849813
-
Necrosis and the serpin under't
-
Abraham MC, Shaham S. (2007). Necrosis and the serpin under't. Dev Cell 13: 464-465.
-
(2007)
Dev Cell
, vol.13
, pp. 464-465
-
-
Abraham, M.C.1
Shaham, S.2
-
2
-
-
0035366499
-
Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture
-
Antunes F, Cadenas E, Brunk UT. (2001). Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture. Biochem J 356: 549-555.
-
(2001)
Biochem J
, vol.356
, pp. 549-555
-
-
Antunes, F.1
Cadenas, E.2
Brunk, U.T.3
-
3
-
-
0043234207
-
Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis
-
Bidere N, Lorenzo HK, Carmona S, Laforge M, Harper F, Dumont C et al. (2003). Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis. J Biol Chem 278: 31401-31411.
-
(2003)
J Biol Chem
, vol.278
, pp. 31401-31411
-
-
Bidere, N.1
Lorenzo, H.K.2
Carmona, S.3
Laforge, M.4
Harper, F.5
Dumont, C.6
-
4
-
-
0035957342
-
The human brm protein is cleaved during apoptosis: The role of cathepsin G
-
Biggs JR, Yang J, Gullberg U, Muchardt C, Yaniv M, Kraft AS. (2001). The human brm protein is cleaved during apoptosis: the role of cathepsin G. Proc Natl Acad Sci USA 98: 3814-3819.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3814-3819
-
-
Biggs, J.R.1
Yang, J.2
Gullberg, U.3
Muchardt, C.4
Yaniv, M.5
Kraft, A.S.6
-
5
-
-
34047097917
-
Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes
-
Bivik C, Rosdahl I, Ollinger K. (2007). Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes. Carcinogenesis 28: 537-544.
-
(2007)
Carcinogenesis
, vol.28
, pp. 537-544
-
-
Bivik, C.1
Rosdahl, I.2
Ollinger, K.3
-
6
-
-
34247849157
-
Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization
-
Blomgran R, Zheng L, Stendahl O. (2007). Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization. J Leukoc Biol 81: 1213-1223.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 1213-1223
-
-
Blomgran, R.1
Zheng, L.2
Stendahl, O.3
-
7
-
-
0038529617
-
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion
-
Boya P, Andreau K, Poncet D, Zamzami N, Perfettini JL, Metivier D et al. (2003a). Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion. J Exp Med 197: 1323-1334.
-
(2003)
J Exp Med
, vol.197
, pp. 1323-1334
-
-
Boya, P.1
Andreau, K.2
Poncet, D.3
Zamzami, N.4
Perfettini, J.L.5
Metivier, D.6
-
8
-
-
0036312001
-
Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization
-
Boya P, Cohen I, Zamzami N, Vieira HLA, Kroemer G. (2002). Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization. Cell Death Differ 9: 465-467.
-
(2002)
Cell Death Differ
, vol.9
, pp. 465-467
-
-
Boya, P.1
Cohen, I.2
Zamzami, N.3
Vieira, H.L.A.4
Kroemer, G.5
-
10
-
-
19944434059
-
Inhibition of macroautophagy triggers apoptosis
-
Boya P, Gonzalez-Polo RA, Casares N, Perfettini J, Dessen P, Larochette N et al. (2005). Inhibition of macroautophagy triggers apoptosis. Mol Cell Biol 25: 1025-1040.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1025-1040
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Casares, N.3
Perfettini, J.4
Dessen, P.5
Larochette, N.6
-
11
-
-
0038677510
-
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
-
Boya P, Gonzalez-Polo RA, Poncet D, Andreau K, Vieira HL, Roumier T et al. (2003b). Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 22: 3927-3936.
-
(2003)
Oncogene
, vol.22
, pp. 3927-3936
-
-
Boya, P.1
Gonzalez-Polo, R.A.2
Poncet, D.3
Andreau, K.4
Vieira, H.L.5
Roumier, T.6
-
12
-
-
9644295779
-
Viral proteins targeting mitochondria: Controlling cell death
-
Boya P, Pauleau AL, Poncet D, Gonzalez-Polo RA, Zamzami N, Kroemer G. (2004). Viral proteins targeting mitochondria: controlling cell death. Biochim Biophys Acta 1659: 178-189.
-
(2004)
Biochim Biophys Acta
, vol.1659
, pp. 178-189
-
-
Boya, P.1
Pauleau, A.L.2
Poncet, D.3
Gonzalez-Polo, R.A.4
Zamzami, N.5
Kroemer, G.6
-
13
-
-
1642576236
-
Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells
-
Broker LE, Huisman C, Span SW, Rodriguez JA, Kruyt FA, Giaccone G. (2004). Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells. Cancer Res 64: 27-30.
-
(2004)
Cancer Res
, vol.64
, pp. 27-30
-
-
Broker, L.E.1
Huisman, C.2
Span, S.W.3
Rodriguez, J.A.4
Kruyt, F.A.5
Giaccone, G.6
-
15
-
-
0038002071
-
Cathepsin L plays an active role in involution of the mouse mammary gland
-
Burke MA, Hutter D, Reshamwala RP, Knepper JE. (2003). Cathepsin L plays an active role in involution of the mouse mammary gland. Dev Dyn 227: 315-322.
-
(2003)
Dev Dyn
, vol.227
, pp. 315-322
-
-
Burke, M.A.1
Hutter, D.2
Reshamwala, R.P.3
Knepper, J.E.4
-
16
-
-
34548247761
-
Molecular effectors of multiple cell death pathways initiated by photodynamic therapy
-
Buytaert E, Dewaele M, Agostinis P. (2007). Molecular effectors of multiple cell death pathways initiated by photodynamic therapy. Biochim Biophys Acta 1776: 86-107.
-
(2007)
Biochim Biophys Acta
, vol.1776
, pp. 86-107
-
-
Buytaert, E.1
Dewaele, M.2
Agostinis, P.3
-
17
-
-
0042744006
-
Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis
-
Canbay A, Guicciardi ME, Higuchi H, Feldstein A, Bronk SF, Rydzewski R et al. (2003). Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis. J Clin Invest 112: 152-159.
-
(2003)
J Clin Invest
, vol.112
, pp. 152-159
-
-
Canbay, A.1
Guicciardi, M.E.2
Higuchi, H.3
Feldstein, A.4
Bronk, S.F.5
Rydzewski, R.6
-
18
-
-
1842480983
-
Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: Influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents
-
Caruso JA, Mathieu PA, Joiakim A, Leeson B, Kessel D, Sloane BF et al. (2004). Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents. Mol Pharmacol 65: 1016-1028.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 1016-1028
-
-
Caruso, J.A.1
Mathieu, P.A.2
Joiakim, A.3
Leeson, B.4
Kessel, D.5
Sloane, B.F.6
-
19
-
-
33744965938
-
Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent
-
Caruso JA, Mathieu PA, Joiakim A, Zhang H, Reiners Jr JJ. (2006). Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent. J Biol Chem 281: 10954-10967.
-
(2006)
J Biol Chem
, vol.281
, pp. 10954-10967
-
-
Caruso, J.A.1
Mathieu, P.A.2
Joiakim, A.3
Zhang, H.4
Reiners Jr, J.J.5
-
20
-
-
29144446112
-
Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy
-
Caruso JA, Mathieu PA, Reiners Jr JJ. (2005). Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy. Biochem J 392: 325-334.
-
(2005)
Biochem J
, vol.392
, pp. 325-334
-
-
Caruso, J.A.1
Mathieu, P.A.2
Reiners Jr, J.J.3
-
21
-
-
33947537430
-
Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells
-
Castino R, Bellio N, Nicotra G, Follo C, Trincheri NF, Isidoro C. (2007). Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells. Free Radic Biol Med 42: 1305-1316.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 1305-1316
-
-
Castino, R.1
Bellio, N.2
Nicotra, G.3
Follo, C.4
Trincheri, N.F.5
Isidoro, C.6
-
22
-
-
28844490007
-
The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway
-
Chen W, Li N, Chen T, Han Y, Li C, Wang Y et al. (2005). The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway. J Biol Chem 280: 40985-40995.
-
(2005)
J Biol Chem
, vol.280
, pp. 40985-40995
-
-
Chen, W.1
Li, N.2
Chen, T.3
Han, Y.4
Li, C.5
Wang, Y.6
-
23
-
-
34548022648
-
Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons
-
Cheung NS, Peng ZF, Chen MJ, Moore PK, Whiteman M. (2007). Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons. Neuropharmacology 53: 505-514.
-
(2007)
Neuropharmacology
, vol.53
, pp. 505-514
-
-
Cheung, N.S.1
Peng, Z.F.2
Chen, M.J.3
Moore, P.K.4
Whiteman, M.5
-
24
-
-
0842278331
-
-
Chipuk JE, Kuwana T, Bouchier-HayesL , Droin NM, Newmeyer DD, Schuler M et al. (2004). Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303: 1010-1014.
-
Chipuk JE, Kuwana T, Bouchier-HayesL , Droin NM, Newmeyer DD, Schuler M et al. (2004). Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303: 1010-1014.
-
-
-
-
25
-
-
0942265544
-
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins
-
Cirman T, Oresic K, Mazovec GD, Turk V, Reed JC, Myers RM et al. (2004). Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J Biol Chem 279: 3578-3587.
-
(2004)
J Biol Chem
, vol.279
, pp. 3578-3587
-
-
Cirman, T.1
Oresic, K.2
Mazovec, G.D.3
Turk, V.4
Reed, J.C.5
Myers, R.M.6
-
26
-
-
0025283961
-
Developmental cell death: Morphological diversity and multiple mechanisms
-
Clarke PG. (1990). Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol (Berl) 181: 195-213.
-
(1990)
Anat Embryol (Berl)
, vol.181
, pp. 195-213
-
-
Clarke, P.G.1
-
27
-
-
34047274469
-
Lens epithelium-derived growth factor isan Hsp70-2 regulated guardian of lysosomal stability in human cancer
-
Daugaard M, Kirkegaard-Sorensen T, Ostenfeld MS, Aaboe M, Hoyer-Hansen M, Orntoft TF et al. (2007a). Lens epithelium-derived growth factor isan Hsp70-2 regulated guardian of lysosomal stability in human cancer. Cancer Res 67: 2559-2567.
-
(2007)
Cancer Res
, vol.67
, pp. 2559-2567
-
-
Daugaard, M.1
Kirkegaard-Sorensen, T.2
Ostenfeld, M.S.3
Aaboe, M.4
Hoyer-Hansen, M.5
Orntoft, T.F.6
-
28
-
-
34447528828
-
The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions
-
Daugaard M, Rohde M, Jaattela M. (2007b). The heat shock protein 70 family: highly homologous proteins with overlapping and distinct functions. FEBS Lett 581: 3702-3710.
-
(2007)
FEBS Lett
, vol.581
, pp. 3702-3710
-
-
Daugaard, M.1
Rohde, M.2
Jaattela, M.3
-
29
-
-
0016260069
-
Commentary. Lysosomotropic agents
-
de Duve C, de Barsy T, Poole B, Trouet A, Tulkens P, Van Hoof F. (1974). Commentary. Lysosomotropic agents. Biochem Pharmacol 23: 2495-2531.
-
(1974)
Biochem Pharmacol
, vol.23
, pp. 2495-2531
-
-
de Duve, C.1
de Barsy, T.2
Poole, B.3
Trouet, A.4
Tulkens, P.5
Van Hoof, F.6
-
30
-
-
0002850020
-
Lysosomes, a new group of cytoplasmic particles
-
Hayashi T ed, Ronald Press Co, New York
-
de Duve C. (1959). Lysosomes, a new group of cytoplasmic particles. In: Hayashi T (ed). Subcellular Particles. Ronald Press Co.: New York.
-
(1959)
Subcellular Particles
-
-
de Duve, C.1
-
31
-
-
34347207246
-
Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species
-
De Milito A, Iessi E, Logozzi M, Lozupone F, Spada M, Marino ML et al. (2007). Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species. Cancer Res 67: 5408-5417.
-
(2007)
Cancer Res
, vol.67
, pp. 5408-5417
-
-
De Milito, A.1
Iessi, E.2
Logozzi, M.3
Lozupone, F.4
Spada, M.5
Marino, M.L.6
-
32
-
-
34247170947
-
Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells
-
Di Piazza M, Mader C, Geletneky K, Herrero YCM, Weber E, Schlehofer J et al. (2007). Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. J Virol 81: 4186-4198.
-
(2007)
J Virol
, vol.81
, pp. 4186-4198
-
-
Di Piazza, M.1
Mader, C.2
Geletneky, K.3
Herrero, Y.C.M.4
Weber, E.5
Schlehofer, J.6
-
33
-
-
0142227699
-
Endosomal and lysosomal effects of desferrioxamine: Protection of HeLa cells from hydrogen peroxide-induced DNA damage and induction of cell-cycle arrest
-
Doulias PT, Christoforidis S, Brunk UT, Galaris D. (2003). Endosomal and lysosomal effects of desferrioxamine: Protection of HeLa cells from hydrogen peroxide-induced DNA damage and induction of cell-cycle arrest. Free Radic Biol Med 35: 719-728.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 719-728
-
-
Doulias, P.T.1
Christoforidis, S.2
Brunk, U.T.3
Galaris, D.4
-
34
-
-
0036569986
-
Molecular bases of cellular iron toxicity
-
Eaton JW, Qian M. (2002). Molecular bases of cellular iron toxicity. Free Radic Biol Med 32: 833-840.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 833-840
-
-
Eaton, J.W.1
Qian, M.2
-
35
-
-
20044383567
-
Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death
-
Emert-Sedlak L, Shangary S, Rabinovitz A, Miranda MB, Delach SM, Johnson DE. (2005). Involvement of cathepsin D in chemotherapy-induced cytochrome c release, caspase activation, and cell death. Mol Cancer Ther 4: 733-742.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 733-742
-
-
Emert-Sedlak, L.1
Shangary, S.2
Rabinovitz, A.3
Miranda, M.B.4
Delach, S.M.5
Johnson, D.E.6
-
36
-
-
11844294713
-
Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis
-
Erdal H, Berndtsson M, Castro J, Brunk U, Shoshan MC, Linder S. (2005). Induction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis. Proc Natl Acad Sci USA 102: 192-197.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 192-197
-
-
Erdal, H.1
Berndtsson, M.2
Castro, J.3
Brunk, U.4
Shoshan, M.C.5
Linder, S.6
-
37
-
-
33749041268
-
Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy
-
Eskelinen EL. (2006). Roles of LAMP-1 and LAMP-2 in lysosome biogenesis and autophagy. Mol Aspects Med 27: 495-502.
-
(2006)
Mol Aspects Med
, vol.27
, pp. 495-502
-
-
Eskelinen, E.L.1
-
38
-
-
3442880143
-
Sensitization to the lysosomal cell death pathway upon immortalization and transformation
-
Fehrenbacher N, Gyrd-Hansen M, Poulsen B, Felbor U, Kallunki T, BoesM et al. (2004). Sensitization to the lysosomal cell death pathway upon immortalization and transformation. Cancer Res 64: 5301-5310.
-
(2004)
Cancer Res
, vol.64
, pp. 5301-5310
-
-
Fehrenbacher, N.1
Gyrd-Hansen, M.2
Poulsen, B.3
Felbor, U.4
Kallunki, T.5
BoesM6
-
39
-
-
17144361820
-
Lysosomes as targets for cancer therapy
-
Fehrenbacher N, Jaattela M. (2005). Lysosomes as targets for cancer therapy. Cancer Res 65: 2993-2995.
-
(2005)
Cancer Res
, vol.65
, pp. 2993-2995
-
-
Fehrenbacher, N.1
Jaattela, M.2
-
40
-
-
0037062449
-
Neuronal loss and brain atrophy in mice lacking cathepsins B and L
-
Felbor U, Kessler B, Mothes W, Goebel HH, Ploegh HL, Bronson RT et al. (2002). Neuronal loss and brain atrophy in mice lacking cathepsins B and L. Proc Natl Acad Sci USA 99: 7883-7888.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7883-7888
-
-
Felbor, U.1
Kessler, B.2
Mothes, W.3
Goebel, H.H.4
Ploegh, H.L.5
Bronson, R.T.6
-
41
-
-
3042824524
-
Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
-
Feldstein AE, Werneburg NW, Canbay A, Guicciardi ME, Bronk SF, Rydzewski R et al. (2004). Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology 40: 185-194.
-
(2004)
Hepatology
, vol.40
, pp. 185-194
-
-
Feldstein, A.E.1
Werneburg, N.W.2
Canbay, A.3
Guicciardi, M.E.4
Bronk, S.F.5
Rydzewski, R.6
-
42
-
-
33646891970
-
Bax inhibition protects against free fatty acid-induced lysosomal permeabilization
-
Feldstein AE, Werneburg NW, Li Z, Bronk SF, Gores GJ. (2006). Bax inhibition protects against free fatty acid-induced lysosomal permeabilization. Am J Physiol Gastrointest Liver Physiol 290: G1339-G1346.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Feldstein, A.E.1
Werneburg, N.W.2
Li, Z.3
Bronk, S.F.4
Gores, G.J.5
-
43
-
-
23944527363
-
Cancer cell injury by cytotoxins from cobra venom is mediated through lysosomal damage
-
Feofanov AV, Sharonov GV, Astapova MV, Rodionov DI, Utkin YN, Arseniev AS. (2005). Cancer cell injury by cytotoxins from cobra venom is mediated through lysosomal damage. Biochem J 390: 11-18.
-
(2005)
Biochem J
, vol.390
, pp. 11-18
-
-
Feofanov, A.V.1
Sharonov, G.V.2
Astapova, M.V.3
Rodionov, D.I.4
Utkin, Y.N.5
Arseniev, A.S.6
-
44
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri KF, Kroemer G. (2001). Organelle-specific initiation of cell death pathways. Nat Cell Biol 3: E255-E263.
-
(2001)
Nat Cell Biol
, vol.3
-
-
Ferri, K.F.1
Kroemer, G.2
-
45
-
-
33749178260
-
Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
-
Festjens N, Vanden Berghe T, Vandenabeele P. (2006). Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. Biochim Biophys Acta 1757: 1371-1387.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 1371-1387
-
-
Festjens, N.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
46
-
-
0019949926
-
Lysosomotropic agents. 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells
-
Firestone RA, Pisano JM, Bailey PJ, Sturm A, Bonney RJ, Wightman P et al. (1982). Lysosomotropic agents. 4. Carbobenzoxyglycylphenylalanyl, a new protease-sensitive masking group for introduction into cells. J Med Chem 25: 539-544.
-
(1982)
J Med Chem
, vol.25
, pp. 539-544
-
-
Firestone, R.A.1
Pisano, J.M.2
Bailey, P.J.3
Sturm, A.4
Bonney, R.J.5
Wightman, P.6
-
47
-
-
0035947776
-
Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
-
Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M et al. (2001). Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 153: 999-1010.
-
(2001)
J Cell Biol
, vol.153
, pp. 999-1010
-
-
Foghsgaard, L.1
Wissing, D.2
Mauch, D.3
Lademann, U.4
Bastholm, L.5
Boes, M.6
-
48
-
-
34250753161
-
Cell death modalities: Classification and pathophysiological implications
-
Galluzzi L, Maiuri MC, Vitale I, Zischka H, Castedo M, Zitvogel L et al. (2007). Cell death modalities: classification and pathophysiological implications. Cell Death Differ 14: 1237-1243.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1237-1243
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
Zischka, H.4
Castedo, M.5
Zitvogel, L.6
-
49
-
-
0042763088
-
LEDGF/p75: A novel nuclear autoantigen at the crossroads of cell survival and apoptosis
-
Ganapathy V, DanielsT, Casiano CA. (2003). LEDGF/p75: a novel nuclear autoantigen at the crossroads of cell survival and apoptosis. Autoimmun Rev 2: 290-297.
-
(2003)
Autoimmun Rev
, vol.2
, pp. 290-297
-
-
Ganapathy, V.1
Daniels, T.2
Casiano, C.A.3
-
50
-
-
34250003522
-
Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells
-
Garnett TO, Filippova M, Duerksen-Hughes PJ. (2007). Bid is cleaved upstream of caspase-8 activation during TRAIL-mediated apoptosis in human osteosarcoma cells. Apoptosis 12: 1299-1315.
-
(2007)
Apoptosis
, vol.12
, pp. 1299-1315
-
-
Garnett, T.O.1
Filippova, M.2
Duerksen-Hughes, P.J.3
-
51
-
-
33751203833
-
Heat shock proteins 27 and 70: Anti-apoptotic proteins with tumorigenic properties
-
Garrido C, Brunet M, Didelot C, Zermati Y, Schmitt E, Kroemer G. (2006). Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties. Cell Cycle 5: 2592-2601.
-
(2006)
Cell Cycle
, vol.5
, pp. 2592-2601
-
-
Garrido, C.1
Brunet, M.2
Didelot, C.3
Zermati, Y.4
Schmitt, E.5
Kroemer, G.6
-
52
-
-
0345791482
-
Extracellular acidification alters lysosomal trafficking in human breast cancer cells
-
Glunde K, Guggino SE, Solaiyappan M, Pathak AP, Ichikawa Y, Bhujwalla ZM. (2003). Extracellular acidification alters lysosomal trafficking in human breast cancer cells. Neoplasia 5: 533-545.
-
(2003)
Neoplasia
, vol.5
, pp. 533-545
-
-
Glunde, K.1
Guggino, S.E.2
Solaiyappan, M.3
Pathak, A.P.4
Ichikawa, Y.5
Bhujwalla, Z.M.6
-
53
-
-
33846018602
-
Cell death by necrosis: Towards a molecular definition
-
Golstein P, Kroemer G. (2007). Cell death by necrosis: towards a molecular definition. Trends Biochem Sci 32: 37-43.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 37-43
-
-
Golstein, P.1
Kroemer, G.2
-
54
-
-
23844483152
-
The apoptosis/autophagy paradox: Autophagic vacuolization before apoptotic death. Inhibition of macroautophagy triggers apoptosis
-
Gonzalez-Polo RA, Boya P, Pauleau AL, Jalil A, Larochette N, Souquere S et al. (2005). The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death. Inhibition of macroautophagy triggers apoptosis. J Cell Sci 118: 3091-3102.
-
(2005)
J Cell Sci
, vol.118
, pp. 3091-3102
-
-
Gonzalez-Polo, R.A.1
Boya, P.2
Pauleau, A.L.3
Jalil, A.4
Larochette, N.5
Souquere, S.6
-
55
-
-
33947235679
-
Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine
-
Groth-Pedersen L, Ostenfeld MS, Hoyer-Hansen M, Nylandsted J, Jaattela M. (2007). Vincristine induces dramatic lysosomal changes and sensitizes cancer cells to lysosome-destabilizing siramesine. Cancer Res 67: 2217-2225.
-
(2007)
Cancer Res
, vol.67
, pp. 2217-2225
-
-
Groth-Pedersen, L.1
Ostenfeld, M.S.2
Hoyer-Hansen, M.3
Nylandsted, J.4
Jaattela, M.5
-
56
-
-
33750601605
-
Functional role of aspartic proteinase cathepsin D in insect metamorphosis
-
Gui ZZ, Lee KS, Kim BY, Choi YS, Wei YD, Choo YM et al. (2006). Functional role of aspartic proteinase cathepsin D in insect metamorphosis. BMC Dev Biol 6: 49.
-
(2006)
BMC Dev Biol
, vol.6
, pp. 49
-
-
Gui, Z.Z.1
Lee, K.S.2
Kim, B.Y.3
Choi, Y.S.4
Wei, Y.D.5
Choo, Y.M.6
-
57
-
-
34347392130
-
cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis
-
Guicciardi ME, Bronk SF, Werneburg NW, Gores GJ. (2007). cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis. Am J Physiol Gastrointest Liver Physiol 292: G1337-G1346.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.292
-
-
Guicciardi, M.E.1
Bronk, S.F.2
Werneburg, N.W.3
Gores, G.J.4
-
58
-
-
22344435528
-
Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis
-
GoresGJ
-
Guicciardi ME, Bronk SF, Werneburg NW, Yin XM, GoresGJ. (2005). Bid is upstream of lysosome-mediated caspase 2 activation in tumor necrosis factor alpha-induced hepatocyte apoptosis. Gastroenterology 129: 269-284.
-
(2005)
Gastroenterology
, vol.129
, pp. 269-284
-
-
Guicciardi, M.E.1
Bronk, S.F.2
Werneburg, N.W.3
Yin, X.M.4
-
59
-
-
0033756474
-
Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
Guicciardi ME, Deussing J, Miyoshi H, Bronk SF, Svingen PA, PetersC et al. (2000). Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest 106: 1127-1137.
-
(2000)
J Clin Invest
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
Deussing, J.2
Miyoshi, H.3
Bronk, S.F.4
Svingen, P.A.5
PetersC6
-
61
-
-
33750307192
-
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9
-
Gyrd-Hansen M, Farkas T, Fehrenbacher N, Bastholm L, Hoyer-Hansen M, Elling F et al. (2006). Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Mol Cell Biol 26: 7880-7891.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7880-7891
-
-
Gyrd-Hansen, M.1
Farkas, T.2
Fehrenbacher, N.3
Bastholm, L.4
Hoyer-Hansen, M.5
Elling, F.6
-
62
-
-
17144394423
-
Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity
-
Gyrd-Hansen M, Nylandsted J, Jaattela M. (2004). Heat shock protein 70 promotes cancer cell viability by safeguarding lysosomal integrity. Cell Cycle 3: 1484-1485.
-
(2004)
Cell Cycle
, vol.3
, pp. 1484-1485
-
-
Gyrd-Hansen, M.1
Nylandsted, J.2
Jaattela, M.3
-
64
-
-
2442661614
-
Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation
-
Heinrich M, Neumeyer J, Jakob M, Hallas C, Tchikov V, Winoto-Morbach S et al. (2004). Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation. Cell Death Differ 11: 550-563.
-
(2004)
Cell Death Differ
, vol.11
, pp. 550-563
-
-
Heinrich, M.1
Neumeyer, J.2
Jakob, M.3
Hallas, C.4
Tchikov, V.5
Winoto-Morbach, S.6
-
65
-
-
37849026130
-
The daily job of night killers: Alternative roles of the BCL-2 family in organelle physiology
-
Hetz C, Glimcher L. (2008). The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology. Trends Cell Biol 18: 38-44.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 38-44
-
-
Hetz, C.1
Glimcher, L.2
-
66
-
-
0035300531
-
Caspase-3 activation by lysosomal enzymes in cytochrome c-independent apoptosis in myelodysplastic syndrome-derived cell line P39
-
Hishita T, Tada-Oikawa S, Tohyama K, Miura Y, Nishihara T, Tohyama Y et al. (2001). Caspase-3 activation by lysosomal enzymes in cytochrome c-independent apoptosis in myelodysplastic syndrome-derived cell line P39. Cancer Res 61: 2878-2884.
-
(2001)
Cancer Res
, vol.61
, pp. 2878-2884
-
-
Hishita, T.1
Tada-Oikawa, S.2
Tohyama, K.3
Miura, Y.4
Nishihara, T.5
Tohyama, Y.6
-
67
-
-
34250024884
-
Lysosomal cathepsin initiates apoptosis, which is regulated by photodamage to Bcl-2 at mitochondria in photodynamic therapy using a novel photosensitizer, ATX-s10 (Na)
-
Ichinose S, Usuda J, Hirata T, Inoue T, Ohtani K, Maehara S et al. (2006). Lysosomal cathepsin initiates apoptosis, which is regulated by photodamage to Bcl-2 at mitochondria in photodynamic therapy using a novel photosensitizer, ATX-s10 (Na). Int J Oncol 29: 349-355.
-
(2006)
Int J Oncol
, vol.29
, pp. 349-355
-
-
Ichinose, S.1
Usuda, J.2
Hirata, T.3
Inoue, T.4
Ohtani, K.5
Maehara, S.6
-
68
-
-
0033494227
-
Participation of a cathepsin L-type protease in the activation of caspase-3
-
Ishisaka R, Utsumi T, Kanno T, Arita K, Katunuma N, Akiyama J et al. (1999). Participation of a cathepsin L-type protease in the activation of caspase-3. Cell Struct Funct 24: 465-470.
-
(1999)
Cell Struct Funct
, vol.24
, pp. 465-470
-
-
Ishisaka, R.1
Utsumi, T.2
Kanno, T.3
Arita, K.4
Katunuma, N.5
Akiyama, J.6
-
69
-
-
0031753981
-
Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line
-
Jones B, Roberts PJ, Faubion WA, Kominami E, Gores GJ. (1998). Cystatin A expression reduces bile salt-induced apoptosis in a rat hepatoma cell line. Am J Physiol 275: G723-G730.
-
(1998)
Am J Physiol
, vol.275
-
-
Jones, B.1
Roberts, P.J.2
Faubion, W.A.3
Kominami, E.4
Gores, G.J.5
-
70
-
-
26244443655
-
Lysosomal membrane permeabilization during apoptosis- involvement of Bax?
-
Kagedal K, Johansson AC, Johansson U, Heimlich G, Roberg K, Wang NS et al. (2005). Lysosomal membrane permeabilization during apoptosis- involvement of Bax? Int J Exp Pathol 86: 309-321.
-
(2005)
Int J Exp Pathol
, vol.86
, pp. 309-321
-
-
Kagedal, K.1
Johansson, A.C.2
Johansson, U.3
Heimlich, G.4
Roberg, K.5
Wang, N.S.6
-
71
-
-
0035408169
-
The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress
-
Kagedal K, Johansson U, Ollinger K. (2001a). The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress. FASEB J 15: 1592-1594.
-
(2001)
FASEB J
, vol.15
, pp. 1592-1594
-
-
Kagedal, K.1
Johansson, U.2
Ollinger, K.3
-
72
-
-
0035887215
-
Sphingosine-induced apoptosis is dependent on lysosomal proteases
-
Kagedal K, Zhao M, Svensson I, Brunk UT. (2001b). Sphingosine-induced apoptosis is dependent on lysosomal proteases. Biochem J 359: 335-343.
-
(2001)
Biochem J
, vol.359
, pp. 335-343
-
-
Kagedal, K.1
Zhao, M.2
Svensson, I.3
Brunk, U.T.4
-
73
-
-
1542285418
-
Simultaneous human papilloma virus type 16 E7 and cdk inhibitor p21 expression induces apoptosis and cathepsin B activation
-
Kaznelson DW, Bruun S, Monrad A, Gjerlov S, Birk J, Ropke C et al. (2004). Simultaneous human papilloma virus type 16 E7 and cdk inhibitor p21 expression induces apoptosis and cathepsin B activation. Virology 320: 301-312.
-
(2004)
Virology
, vol.320
, pp. 301-312
-
-
Kaznelson, D.W.1
Bruun, S.2
Monrad, A.3
Gjerlov, S.4
Birk, J.5
Ropke, C.6
-
74
-
-
35448981935
-
Autophagy: From phenomenology to molecular understanding in less than a decade
-
Klionsky DJ. (2007). Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 8: 931-937.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 931-937
-
-
Klionsky, D.J.1
-
75
-
-
0034666116
-
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons
-
Koike M, Nakanishi H, Saftig P, Ezaki J, Isahara K, Ohsawa Y et al. (2000). Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons. J Neurosci Res 20: 6898-6906.
-
(2000)
J Neurosci Res
, vol.20
, pp. 6898-6906
-
-
Koike, M.1
Nakanishi, H.2
Saftig, P.3
Ezaki, J.4
Isahara, K.5
Ohsawa, Y.6
-
76
-
-
27644575157
-
Coordinating ERK/MAPK signalling through scaffolds and inhibitors
-
Kolch W. (2005). Coordinating ERK/MAPK signalling through scaffolds and inhibitors. Nat Rev Mol Cell Biol 6: 827-837.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 827-837
-
-
Kolch, W.1
-
77
-
-
43449110717
-
p38 MAPK plays an essential role in apoptosis induced by photoactivation of a novel ethylene glycol porphyrin derivative
-
Kralova J, Dvorak M, Koc M, Kral V. (2007). p38 MAPK plays an essential role in apoptosis induced by photoactivation of a novel ethylene glycol porphyrin derivative. Oncogene 27: 3010-3020.
-
(2007)
Oncogene
, vol.27
, pp. 3010-3020
-
-
Kralova, J.1
Dvorak, M.2
Koc, M.3
Kral, V.4
-
78
-
-
22544432640
-
Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death
-
Kroemer G, El-Deiry W, Golstein P, Peter M, Vaux D, Vandenabeele P et al. (2005). Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 12(Suppl 2): 1463-1467.
-
(2005)
Cell Death Differ
, vol.12
, Issue.SUPPL. 2
, pp. 1463-1467
-
-
Kroemer, G.1
El-Deiry, W.2
Golstein, P.3
Peter, M.4
Vaux, D.5
Vandenabeele, P.6
-
79
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
Kroemer G, Galluzzi L, Brenner C. (2007). Mitochondrial membrane permeabilization in cell death. Physiol Rev 87: 99-163.
-
(2007)
Physiol Rev
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
80
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
Kroemer G, Jaattela M. (2005). Lysosomes and autophagy in cell death control. Nat Rev Cancer 5: 886-897.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 886-897
-
-
Kroemer, G.1
Jaattela, M.2
-
81
-
-
33745205646
-
Intralysosomal iron chelation protects against oxidative stress-induced cellular damage
-
Kurz T, Gustafsson B, Brunk UT. (2006). Intralysosomal iron chelation protects against oxidative stress-induced cellular damage. FEBS J 273: 3106-3117.
-
(2006)
FEBS J
, vol.273
, pp. 3106-3117
-
-
Kurz, T.1
Gustafsson, B.2
Brunk, U.T.3
-
82
-
-
13944277343
-
BH3 domainsof BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR et al. (2005). BH3 domainsof BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell 17: 525-535.
-
(2005)
Mol Cell
, vol.17
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
-
83
-
-
35148833480
-
Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein Nef
-
Laforge M, Petit F, Estaquier J, Senik A. (2007). Commitment to apoptosis in CD4(+) T lymphocytes productively infected with human immunodeficiency virus type 1 is initiated by lysosomal membrane permeabilization, itself induced by the isolated expression of the viral protein Nef. J Virol 81: 11426-11440.
-
(2007)
J Virol
, vol.81
, pp. 11426-11440
-
-
Laforge, M.1
Petit, F.2
Estaquier, J.3
Senik, A.4
-
84
-
-
33644599456
-
BID-deficient breast cancer MCF-7 cells as a model for the study of autophagy in cancer therapy
-
Lamparska-Przybysz M, Gajkowska B, Motyl T. (2006). BID-deficient breast cancer MCF-7 cells as a model for the study of autophagy in cancer therapy. Autophagy 2: 47-48.
-
(2006)
Autophagy
, vol.2
, pp. 47-48
-
-
Lamparska-Przybysz, M.1
Gajkowska, B.2
Motyl, T.3
-
85
-
-
33747862007
-
An overview of the serpin superfamily
-
Law RH, Zhang Q, McGowan S, Buckle AM, Silverman GA, Wong W et al. (2006). An overview of the serpin superfamily. Genome Biol 7: 216.
-
(2006)
Genome Biol
, vol.7
, pp. 216
-
-
Law, R.H.1
Zhang, Q.2
McGowan, S.3
Buckle, A.M.4
Silverman, G.A.5
Wong, W.6
-
86
-
-
0036387157
-
Steroid regulation of midgut cell death during Drosophila development
-
Lee CY, Cooksey BAK, Baehrecke EH. (2002). Steroid regulation of midgut cell death during Drosophila development. Dev Biol 250: 101-111.
-
(2002)
Dev Biol
, vol.250
, pp. 101-111
-
-
Lee, C.Y.1
Cooksey, B.A.K.2
Baehrecke, E.H.3
-
87
-
-
33646027045
-
Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway
-
Lee J, Remold HG, Ieong MH, Kornfeld H. (2006). Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway. J Immunol 176: 4267-4274.
-
(2006)
J Immunol
, vol.176
, pp. 4267-4274
-
-
Lee, J.1
Remold, H.G.2
Ieong, M.H.3
Kornfeld, H.4
-
88
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. (2008). Autophagy in the pathogenesis of disease. Cell 132: 27-42.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
89
-
-
22544442744
-
The cathepsin B death pathway contributes to TNF plus IFN-gamma-mediated human endothelial injury
-
Li JH, Pober JS. (2005). The cathepsin B death pathway contributes to TNF plus IFN-gamma-mediated human endothelial injury. J Immunol 175: 1858-1866.
-
(2005)
J Immunol
, vol.175
, pp. 1858-1866
-
-
Li, J.H.1
Pober, J.S.2
-
90
-
-
37048999377
-
Adaptor protein LAPF recruits phosphorylated p53 to lysosomes and triggers lysosomal destabilization in apoptosis
-
Li N, Zheng Y, Chen W, Wang C, Liu X, He W et al. (2007). Adaptor protein LAPF recruits phosphorylated p53 to lysosomes and triggers lysosomal destabilization in apoptosis. Cancer Res 67: 11176-11185.
-
(2007)
Cancer Res
, vol.67
, pp. 11176-11185
-
-
Li, N.1
Zheng, Y.2
Chen, W.3
Wang, C.4
Liu, X.5
He, W.6
-
91
-
-
34250025633
-
Engulfment is required for cell competition
-
Li W, Baker NE. (2007). Engulfment is required for cell competition. Cell 129: 1215-1225.
-
(2007)
Cell
, vol.129
, pp. 1215-1225
-
-
Li, W.1
Baker, N.E.2
-
92
-
-
0034677741
-
Induction of cell death by the lysosomotropic detergent MSDH
-
Li W, Yuan X, Nordgren G, Dalen H, Dubowchik GM, Firestone RA et al. (2000). Induction of cell death by the lysosomotropic detergent MSDH. FEBS Lett 470: 35-39.
-
(2000)
FEBS Lett
, vol.470
, pp. 35-39
-
-
Li, W.1
Yuan, X.2
Nordgren, G.3
Dalen, H.4
Dubowchik, G.M.5
Firestone, R.A.6
-
93
-
-
15044344243
-
Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis
-
Li W, Yuan XM. (2004). Increased expression and translocation of lysosomal cathepsins contribute to macrophage apoptosis in atherogenesis. Ann N Y Acad Sci 1030: 427-433.
-
(2004)
Ann N Y Acad Sci
, vol.1030
, pp. 427-433
-
-
Li, W.1
Yuan, X.M.2
-
94
-
-
0032418899
-
OxLDL-induced macrophage cytotoxicity is mediated by lysosomal rupture and modified by intralysosomal redox-active iron
-
Li W, Yuan XM, Brunk UT. (1998). OxLDL-induced macrophage cytotoxicity is mediated by lysosomal rupture and modified by intralysosomal redox-active iron. Free Radic Res 29: 389-398.
-
(1998)
Free Radic Res
, vol.29
, pp. 389-398
-
-
Li, W.1
Yuan, X.M.2
Brunk, U.T.3
-
95
-
-
0038641715
-
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin
-
Li W, Yuan XM, Ivanova S, Tracey KJ, Eaton JW, Brunk UT. (2003). 3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin. Biochem J 371: 429-436.
-
(2003)
Biochem J
, vol.371
, pp. 429-436
-
-
Li, W.1
Yuan, X.M.2
Ivanova, S.3
Tracey, K.J.4
Eaton, J.W.5
Brunk, U.T.6
-
96
-
-
0027469618
-
Iron loading of cultured cardiac myocytes modifies sarcolemmal structure and increases lysosomal fragility
-
Link G, Pinson A, Hershko C. (1993). Iron loading of cultured cardiac myocytes modifies sarcolemmal structure and increases lysosomal fragility. J Lab Clin Med 121: 127-134.
-
(1993)
J Lab Clin Med
, vol.121
, pp. 127-134
-
-
Link, G.1
Pinson, A.2
Hershko, C.3
-
97
-
-
4043106252
-
Lysosomal cysteine proteases in atherosclerosis
-
Liu J, Sukhova GK, Sun JS, Xu WH, Libby P, Shi GP. (2004a). Lysosomal cysteine proteases in atherosclerosis. Arterioscler Thromb Vasc Biol 24: 1359-1366.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1359-1366
-
-
Liu, J.1
Sukhova, G.K.2
Sun, J.S.3
Xu, W.H.4
Libby, P.5
Shi, G.P.6
-
98
-
-
4644295842
-
Serine protease inhibitor 2A is a protective factor for memory T cell development
-
Liu N, Phillips T, Zhang M, Wang Y, Opferman JT, Shah R et al. (2004b). Serine protease inhibitor 2A is a protective factor for memory T cell development. Nat Immunol 5: 919-926.
-
(2004)
Nat Immunol
, vol.5
, pp. 919-926
-
-
Liu, N.1
Phillips, T.2
Zhang, M.3
Wang, Y.4
Opferman, J.T.5
Shah, R.6
-
99
-
-
0141753121
-
NF-kappaB protects from the lysosomal pathway of cell death
-
Liu N, Raja SM, Zazzeroni F, Metkar SS, Shah R, Zhang M et al. (2003). NF-kappaB protects from the lysosomal pathway of cell death. EMBO J 22: 5313-5322.
-
(2003)
EMBO J
, vol.22
, pp. 5313-5322
-
-
Liu, N.1
Raja, S.M.2
Zazzeroni, F.3
Metkar, S.S.4
Shah, R.5
Zhang, M.6
-
100
-
-
3042589745
-
Serine protease inhibitor 2A inhibits caspase-independent cell death
-
Liu N, Wang Y, Ashton-Rickardt PG. (2004c). Serine protease inhibitor 2A inhibits caspase-independent cell death. FEBS Lett 569: 49-53.
-
(2004)
FEBS Lett
, vol.569
, pp. 49-53
-
-
Liu, N.1
Wang, Y.2
Ashton-Rickardt, P.G.3
-
101
-
-
13244252344
-
Apolipoprotein 16, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells
-
Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA. (2005). Apolipoprotein 16, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells. Mol Cancer Res 3: 21-31.
-
(2005)
Mol Cancer Res
, vol.3
, pp. 21-31
-
-
Liu, Z.1
Lu, H.2
Jiang, Z.3
Pastuszyn, A.4
Hu, C.A.5
-
102
-
-
34648815810
-
Emerging roles of proteases in tumour suppression
-
Lopez-Otin C, Matrisian LM. (2007). Emerging roles of proteases in tumour suppression. Nat Rev Cancer 7: 800-808.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 800-808
-
-
Lopez-Otin, C.1
Matrisian, L.M.2
-
103
-
-
34548754372
-
An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury
-
Luke CJ, Pak SC, Askew YS, Naviglia TL, Askew DJ, Nobar SM et al. (2007). An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury. Cell 130: 1108-1119.
-
(2007)
Cell
, vol.130
, pp. 1108-1119
-
-
Luke, C.J.1
Pak, S.C.2
Askew, Y.S.3
Naviglia, T.L.4
Askew, D.J.5
Nobar, S.M.6
-
105
-
-
0037742249
-
Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis
-
Madge LA, Li JH, Choi J, Pober JS. (2003). Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis. J Biol Chem 278: 21295-21306.
-
(2003)
J Biol Chem
, vol.278
, pp. 21295-21306
-
-
Madge, L.A.1
Li, J.H.2
Choi, J.3
Pober, J.S.4
-
107
-
-
0021922646
-
Characterization of iron-mediated peroxidative injury in isolated hepatic lysosomes
-
Mak IT, Weglicki WB. (1985). Characterization of iron-mediated peroxidative injury in isolated hepatic lysosomes. J Clin Invest 75: 58-63.
-
(1985)
J Clin Invest
, vol.75
, pp. 58-63
-
-
Mak, I.T.1
Weglicki, W.B.2
-
108
-
-
33749643860
-
Lysosomes as the target of yessotoxin in invertebrate and vertebrate cell lines
-
Malagoli D, Marchesini E, Ottaviani E. (2006). Lysosomes as the target of yessotoxin in invertebrate and vertebrate cell lines. Toxicol Lett 167: 75-83.
-
(2006)
Toxicol Lett
, vol.167
, pp. 75-83
-
-
Malagoli, D.1
Marchesini, E.2
Ottaviani, E.3
-
109
-
-
0035904232
-
S-Nitrosylation of mitochondrial caspases
-
Mannick JB, Schonhoff C, Papeta N, Ghafourifar P, Szibor M, Fang K et al. (2001). S-Nitrosylation of mitochondrial caspases. J Cell Biol 154: 1111-1116.
-
(2001)
J Cell Biol
, vol.154
, pp. 1111-1116
-
-
Mannick, J.B.1
Schonhoff, C.2
Papeta, N.3
Ghafourifar, P.4
Szibor, M.5
Fang, K.6
-
110
-
-
1242317777
-
Mercury- and copper-induced lysosomal membrane destabilisation depends on [Ca2+]i dependent phospholipase A2 activation
-
Marchi B, Burlando B, Moore MN, Viarengo A. (2004). Mercury- and copper-induced lysosomal membrane destabilisation depends on [Ca2+]i dependent phospholipase A2 activation. Aquat Toxicol 66: 197-204.
-
(2004)
Aquat Toxicol
, vol.66
, pp. 197-204
-
-
Marchi, B.1
Burlando, B.2
Moore, M.N.3
Viarengo, A.4
-
111
-
-
43749102922
-
Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway
-
Miao Q, Sun Y, Wei T, Zhao X, Zhao K, Yan L et al. (2008). Chymotrypsin B cached in rat liver lysosomes and involved in apoptotic regulation through a mitochondrial pathway. J Biol Chem 283: 8218-8228.
-
(2008)
J Biol Chem
, vol.283
, pp. 8218-8228
-
-
Miao, Q.1
Sun, Y.2
Wei, T.3
Zhao, X.4
Zhao, K.5
Yan, L.6
-
112
-
-
2142773262
-
Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: A possible mechanism of high dose tolerance
-
Michallet MC, Saltel F, Flacher M, Revillard JP, Genestier L. (2004). Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance. J Immunol 172: 5405-5414.
-
(2004)
J Immunol
, vol.172
, pp. 5405-5414
-
-
Michallet, M.C.1
Saltel, F.2
Flacher, M.3
Revillard, J.P.4
Genestier, L.5
-
113
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P et al. (2003). p53 has a direct apoptogenic role at the mitochondria. Mol Cell 11: 577-590.
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
-
115
-
-
36249025723
-
Autophagy: Process and function
-
Mizushima N. (2007). Autophagy: process and function. Genes Dev 21: 2861-2873.
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
117
-
-
34250892516
-
The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C
-
Mohlig H, Mathieu S, Thon L, Frederiksen MC, Ward DM, Kaplan J et al. (2007). The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C. Exp Cell Res 313: 2703-2718.
-
(2007)
Exp Cell Res
, vol.313
, pp. 2703-2718
-
-
Mohlig, H.1
Mathieu, S.2
Thon, L.3
Frederiksen, M.C.4
Ward, D.M.5
Kaplan, J.6
-
118
-
-
0033794124
-
Signaling pathways in cell death and survival after photodynamic therapy
-
Moor AC. (2000). Signaling pathways in cell death and survival after photodynamic therapy. J Photochem Photobiol B 57: 1-13.
-
(2000)
J Photochem Photobiol B
, vol.57
, pp. 1-13
-
-
Moor, A.C.1
-
119
-
-
0038605721
-
Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
-
Mousavi SA, Brech A, Berg T, Kjeken R. (2003). Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes. Biochem J 372: 861-869.
-
(2003)
Biochem J
, vol.372
, pp. 861-869
-
-
Mousavi, S.A.1
Brech, A.2
Berg, T.3
Kjeken, R.4
-
121
-
-
4344651318
-
Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
-
Nylandsted J, Gyrd-Hansen M, Danielewicz A, Fehrenbacher N, Lademann U, Hoyer-Hansen M et al. (2004). Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J Exp Med 200: 425-435.
-
(2004)
J Exp Med
, vol.200
, pp. 425-435
-
-
Nylandsted, J.1
Gyrd-Hansen, M.2
Danielewicz, A.3
Fehrenbacher, N.4
Lademann, U.5
Hoyer-Hansen, M.6
-
122
-
-
0034608892
-
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
-
Nylandsted J, Rohde M, Brand K, Bastholm L, Elling F, Jaattela M. (2000). Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2. Proc Natl Acad Sci USA 97: 7871-7876.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 7871-7876
-
-
Nylandsted, J.1
Rohde, M.2
Brand, K.3
Bastholm, L.4
Elling, F.5
Jaattela, M.6
-
123
-
-
0037223288
-
Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death
-
Ono K, Kim SO, Han J. (2003). Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death. Mol Cell Biol 23: 665-676.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 665-676
-
-
Ono, K.1
Kim, S.O.2
Han, J.3
-
124
-
-
25444483322
-
Effective tumor cell death by sigma-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress
-
Ostenfeld MS, Fehrenbacher N, Hoyer-Hansen M, Thomsen C, FarkasT, Jaattela M. (2005). Effective tumor cell death by sigma-2 receptor ligand siramesine involves lysosomal leakage and oxidative stress. Cancer Res 65: 8975-8983.
-
(2005)
Cancer Res
, vol.65
, pp. 8975-8983
-
-
Ostenfeld, M.S.1
Fehrenbacher, N.2
Hoyer-Hansen, M.3
Thomsen, C.4
Farkas, T.5
Jaattela, M.6
-
125
-
-
37549070672
-
Cysteine cathepsin proteases as pharmacological targets in cancer
-
Palermo C, Joyce JA. (2008). Cysteine cathepsin proteases as pharmacological targets in cancer. Trends Pharmacol Sci 29: 22-28.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 22-28
-
-
Palermo, C.1
Joyce, J.A.2
-
126
-
-
18644376106
-
Caspase- and mitochondrial dysfunction-dependent mechanisms of lysosomal leakage and cathepsin B activation in DNA damage-induced apoptosis
-
Paquet C, Sane AT, Beauchemin M, Bertrand R. (2005). Caspase- and mitochondrial dysfunction-dependent mechanisms of lysosomal leakage and cathepsin B activation in DNA damage-induced apoptosis. Leukemia 19: 784-791.
-
(2005)
Leukemia
, vol.19
, pp. 784-791
-
-
Paquet, C.1
Sane, A.T.2
Beauchemin, M.3
Bertrand, R.4
-
127
-
-
34249978223
-
Lysosomal and mitochondrial pathways in miltefosine-induced apoptosis in U937 cells
-
Paris C, Bertoglio J, Breard J. (2007). Lysosomal and mitochondrial pathways in miltefosine-induced apoptosis in U937 cells. Apoptosis 12: 1257-1267.
-
(2007)
Apoptosis
, vol.12
, pp. 1257-1267
-
-
Paris, C.1
Bertoglio, J.2
Breard, J.3
-
128
-
-
22344443961
-
Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes
-
Perez-Morga D, Vanhollebeke B, Paturiaux-Hanocq F, Nolan DP, LinsL, Homble F et al. (2005). Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes. Science 309: 469-472.
-
(2005)
Science
, vol.309
, pp. 469-472
-
-
Perez-Morga, D.1
Vanhollebeke, B.2
Paturiaux-Hanocq, F.3
Nolan, D.P.4
Lins, L.5
Homble, F.6
-
129
-
-
34547569644
-
The cysteine protease inhibitors cystatins inhibit herpes simplex virus type 1-induced apoptosis and virus yield in HEp-2 cells
-
Peri P, Hukkanen V, Nuutila K, Saukko P, Abrahamson M, Vuorinen T. (2007). The cysteine protease inhibitors cystatins inhibit herpes simplex virus type 1-induced apoptosis and virus yield in HEp-2 cells. J Gen Virol 88: 2101-2105.
-
(2007)
J Gen Virol
, vol.88
, pp. 2101-2105
-
-
Peri, P.1
Hukkanen, V.2
Nuutila, K.3
Saukko, P.4
Abrahamson, M.5
Vuorinen, T.6
-
130
-
-
34247345833
-
The apoptosome: Signalling platform of cell death
-
Riedl SJ, Salvesen GS. (2007). The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 8: 405-413.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
131
-
-
0033436344
-
Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress
-
Roberg K, Johansson U, Ollinger K. (1999). Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress. Free Radic Biol Med 27: 1228-1237.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 1228-1237
-
-
Roberg, K.1
Johansson, U.2
Ollinger, K.3
-
132
-
-
0030862412
-
Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes
-
Roberts LR, Kurosawa H, Bronk SF, Fesmier PJ, Agellon LB, Leung WY et al. (1997). Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes. Gastroenterology 113: 1714-1726.
-
(1997)
Gastroenterology
, vol.113
, pp. 1714-1726
-
-
Roberts, L.R.1
Kurosawa, H.2
Bronk, S.F.3
Fesmier, P.J.4
Agellon, L.B.5
Leung, W.Y.6
-
133
-
-
0033845480
-
The combination of Bcl-2 expression and NGF-deprivation facilitates the selective destruction of BAD protein in living sympathetic neurons
-
Roberts ML, Virdee K, Sampson CPB, Gordon I, Parone P, Tolkovsky AM. (2000). The combination of Bcl-2 expression and NGF-deprivation facilitates the selective destruction of BAD protein in living sympathetic neurons. Mol Cell Neurosci 16: 97-110.
-
(2000)
Mol Cell Neurosci
, vol.16
, pp. 97-110
-
-
Roberts, M.L.1
Virdee, K.2
Sampson, C.P.B.3
Gordon, I.4
Parone, P.5
Tolkovsky, A.M.6
-
134
-
-
14644435819
-
Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms
-
Rohde M, Daugaard M, Jensen MH, Helin K, Nylandsted J, Jaattela M. (2005). Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms. Genes Dev 19: 570-582.
-
(2005)
Genes Dev
, vol.19
, pp. 570-582
-
-
Rohde, M.1
Daugaard, M.2
Jensen, M.H.3
Helin, K.4
Nylandsted, J.5
Jaattela, M.6
-
135
-
-
33845733075
-
Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta- hydroxycholesterol triggered apoptosis in human colon cancer cells
-
Roussi S, Gosse F, Aoude-Werner D, Zhang X, Marchioni E, Geoffroy P et al. (2007). Mitochondrial perturbation, oxidative stress and lysosomal destabilization are involved in 7beta-hydroxysitosterol and 7beta- hydroxycholesterol triggered apoptosis in human colon cancer cells. Apoptosis 12: 87-96.
-
(2007)
Apoptosis
, vol.12
, pp. 87-96
-
-
Roussi, S.1
Gosse, F.2
Aoude-Werner, D.3
Zhang, X.4
Marchioni, E.5
Geoffroy, P.6
-
136
-
-
0034486945
-
Imaging proteolysis by living human breast cancer cells
-
Sameni M, Moin K, Sloane BF. (2000). Imaging proteolysis by living human breast cancer cells. Neoplasia 2: 496-504.
-
(2000)
Neoplasia
, vol.2
, pp. 496-504
-
-
Sameni, M.1
Moin, K.2
Sloane, B.F.3
-
137
-
-
42149092670
-
Cathepsin B is involved in the apoptosis intrinsic pathway induced by Bacillus Calmette-Guerin in transitional cancer cell lines
-
Sandes E, Lodillinsky C, Cwirenbaum R, Arguelles C, Casabe A, Eijan AM. (2007). Cathepsin B is involved in the apoptosis intrinsic pathway induced by Bacillus Calmette-Guerin in transitional cancer cell lines. Int J Mol Med 20: 823-828.
-
(2007)
Int J Mol Med
, vol.20
, pp. 823-828
-
-
Sandes, E.1
Lodillinsky, C.2
Cwirenbaum, R.3
Arguelles, C.4
Casabe, A.5
Eijan, A.M.6
-
138
-
-
0035823595
-
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
-
Silverman GA, Bird PI, Carrell RW, Church FC, Coughlin PB, Gettins PG et al. (2001). The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J Biol Chem 276: 33293-33296.
-
(2001)
J Biol Chem
, vol.276
, pp. 33293-33296
-
-
Silverman, G.A.1
Bird, P.I.2
Carrell, R.W.3
Church, F.C.4
Coughlin, P.B.5
Gettins, P.G.6
-
139
-
-
34748831073
-
Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes
-
Stahl S, Reinders Y, Asan E, Mothes W, Conzelmann E, Sickmann A et al. (2007). Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes. Biochim Biophys Acta 1774: 1237-1246.
-
(2007)
Biochim Biophys Acta
, vol.1774
, pp. 1237-1246
-
-
Stahl, S.1
Reinders, Y.2
Asan, E.3
Mothes, W.4
Conzelmann, E.5
Sickmann, A.6
-
140
-
-
0037362831
-
Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice
-
Sukhova GK, Zhang Y, Pan JH, Wada Y, Yamamoto T, Naito M et al. (2003). Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice. J Clin Invest 111: 897-906.
-
(2003)
J Clin Invest
, vol.111
, pp. 897-906
-
-
Sukhova, G.K.1
Zhang, Y.2
Pan, J.H.3
Wada, Y.4
Yamamoto, T.5
Naito, M.6
-
141
-
-
33646128014
-
Lysosomes and lysosomal proteins in cancer cell death (new players of an old struggle)
-
Tardy C, Codogno P, Autefage H, Levade T, Andrieu-Abadie N. (2006). Lysosomes and lysosomal proteins in cancer cell death (new players of an old struggle). Biochim Biophys Acta 1765: 101-125.
-
(2006)
Biochim Biophys Acta
, vol.1765
, pp. 101-125
-
-
Tardy, C.1
Codogno, P.2
Autefage, H.3
Levade, T.4
Andrieu-Abadie, N.5
-
144
-
-
3242808193
-
Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity
-
Thibodeau MS, Giardina C, Knecht DA, Helble J, Hubbard AK. (2004). Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicol Sci 80: 34-48.
-
(2004)
Toxicol Sci
, vol.80
, pp. 34-48
-
-
Thibodeau, M.S.1
Giardina, C.2
Knecht, D.A.3
Helble, J.4
Hubbard, A.K.5
-
145
-
-
34447100874
-
Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D
-
Trincheri NF, Nicotra G, Follo C, Castino R, Isidoro C. (2007). Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D. Carcinogenesis 28: 922-931.
-
(2007)
Carcinogenesis
, vol.28
, pp. 922-931
-
-
Trincheri, N.F.1
Nicotra, G.2
Follo, C.3
Castino, R.4
Isidoro, C.5
-
146
-
-
34249893895
-
Protease signalling in cell death: Caspases versus cysteine cathepsins
-
Turk B, Stoka V. (2007). Protease signalling in cell death: caspases versus cysteine cathepsins. FEBS Lett 581: 2761-2767.
-
(2007)
FEBS Lett
, vol.581
, pp. 2761-2767
-
-
Turk, B.1
Stoka, V.2
-
147
-
-
0035801514
-
Lysosomal cysteine proteases: Facts and opportunities
-
Turk V, Turk B, Turk D. (2001). Lysosomal cysteine proteases: facts and opportunities. EMBO J 20: 4629-4633.
-
(2001)
EMBO J
, vol.20
, pp. 4629-4633
-
-
Turk, V.1
Turk, B.2
Turk, D.3
-
148
-
-
0032728949
-
Mechanism of apoptosis induced by a lysosomotropic agent, L-Leucyl-L-Leucine methyl ester
-
Uchimoto T, Nohara H, Kamehara R, Iwamura M, Watanabe N, Kobayashi Y. (1999). Mechanism of apoptosis induced by a lysosomotropic agent, L-Leucyl-L-Leucine methyl ester. Apoptosis 4: 357-362.
-
(1999)
Apoptosis
, vol.4
, pp. 357-362
-
-
Uchimoto, T.1
Nohara, H.2
Kamehara, R.3
Iwamura, M.4
Watanabe, N.5
Kobayashi, Y.6
-
149
-
-
34250716965
-
-
van der Wel N, Hava D, Houben D, Fluitsma D, van Zon M, Pierson J et al. (2007). M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell 129: 1287-1298.
-
van der Wel N, Hava D, Houben D, Fluitsma D, van Zon M, Pierson J et al. (2007). M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell 129: 1287-1298.
-
-
-
-
150
-
-
0031793017
-
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity
-
Vancompernolle K, Van Herreweghe F, Pynaert G, Van de Craen M, De Vos K, Totty N et al. (1998). Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity. FEBS Lett 438: 150-158.
-
(1998)
FEBS Lett
, vol.438
, pp. 150-158
-
-
Vancompernolle, K.1
Van Herreweghe, F.2
Pynaert, G.3
Van de Craen, M.4
De Vos, K.5
Totty, N.6
-
151
-
-
33748487618
-
The function of apolipoproteins L
-
Vanhollebeke B, Pays E. (2006). The function of apolipoproteins L. Cell Mol Life Sci 63: 1937-1944.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 1937-1944
-
-
Vanhollebeke, B.1
Pays, E.2
-
152
-
-
38649084746
-
Dual contrasting roles of cysteine cathepsins in cancer progression: Apoptosis versus tumour invasion
-
Vasiljeva O, Turk B. (2008). Dual contrasting roles of cysteine cathepsins in cancer progression: apoptosis versus tumour invasion. Biochimie 90: 380-386.
-
(2008)
Biochimie
, vol.90
, pp. 380-386
-
-
Vasiljeva, O.1
Turk, B.2
-
153
-
-
0034330540
-
Analysis of the lysosomal storage disease Chediak-Higashi syndrome
-
Ward DM, Griffiths GM, Stinchcombe JC, Kaplan J. (2000). Analysis of the lysosomal storage disease Chediak-Higashi syndrome. Traffic 1: 816-822.
-
(2000)
Traffic
, vol.1
, pp. 816-822
-
-
Ward, D.M.1
Griffiths, G.M.2
Stinchcombe, J.C.3
Kaplan, J.4
-
154
-
-
0038408712
-
Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis
-
Welss T, Sun J, Irving JA, Blum R, Smith AI, Whisstock JC et al. (2003). Hurpin is a selective inhibitor of lysosomal cathepsin L and protects keratinocytes from ultraviolet-induced apoptosis. Biochemistry 42: 7381-7389.
-
(2003)
Biochemistry
, vol.42
, pp. 7381-7389
-
-
Welss, T.1
Sun, J.2
Irving, J.A.3
Blum, R.4
Smith, A.I.5
Whisstock, J.C.6
-
157
-
-
35348948380
-
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins
-
GoresGJ
-
Werneburg NW, Guicciardi ME, Bronk SF, Kaufmann SH, GoresGJ. (2007). Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins. J Biol Chem 282: 28960-28970.
-
(2007)
J Biol Chem
, vol.282
, pp. 28960-28970
-
-
Werneburg, N.W.1
Guicciardi, M.E.2
Bronk, S.F.3
Kaufmann, S.H.4
-
158
-
-
0242674401
-
Photodamage to multiple Bcl-xL isoforms by photodynamic therapy with the phthalocyanine photosensitizer Pc 4
-
Xue LY, Chiu SM, Fiebig A, AndrewsDW, Oleinick NL. (2003). Photodamage to multiple Bcl-xL isoforms by photodynamic therapy with the phthalocyanine photosensitizer Pc 4. Oncogene 22: 9197-9204.
-
(2003)
Oncogene
, vol.22
, pp. 9197-9204
-
-
Xue, L.Y.1
Chiu, S.M.2
Fiebig, A.3
Andrews, D.W.4
Oleinick, N.L.5
-
159
-
-
39749173737
-
Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells
-
Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H et al. (2008). Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells. Mol Cancer Ther 7: 297-313.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 297-313
-
-
Yacoub, A.1
Park, M.A.2
Gupta, P.3
Rahmani, M.4
Zhang, G.5
Hamed, H.6
-
160
-
-
33645961854
-
Contributions of autophagic and apoptotic mechanisms to CrTX-induced death of K562 cells
-
Yan CH, Liang ZQ, Gu ZL, Yang YP, Reid P, Qin ZH. (2006). Contributions of autophagic and apoptotic mechanisms to CrTX-induced death of K562 cells. Toxicon 47: 521-530.
-
(2006)
Toxicon
, vol.47
, pp. 521-530
-
-
Yan, C.H.1
Liang, Z.Q.2
Gu, Z.L.3
Yang, Y.P.4
Reid, P.5
Qin, Z.H.6
-
161
-
-
33746926747
-
Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes
-
Yap YW, Whiteman M, Bay BH, Li Y, Sheu FS, Qi RZ et al. (2006). Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes. J Neurochem 98: 1597-1609.
-
(2006)
J Neurochem
, vol.98
, pp. 1597-1609
-
-
Yap, Y.W.1
Whiteman, M.2
Bay, B.H.3
Li, Y.4
Sheu, F.S.5
Qi, R.Z.6
-
162
-
-
33744959426
-
PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells
-
Yeung BH, Huang DC, Sinicrope FA. (2006). PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells. J Biol Chem 281: 11923-11932.
-
(2006)
J Biol Chem
, vol.281
, pp. 11923-11932
-
-
Yeung, B.H.1
Huang, D.C.2
Sinicrope, F.A.3
-
163
-
-
21344469549
-
Lysosomal and mitochondrial pathwaysin H2O2-induced apoptosis of alveolar type II cells
-
Yin L, Stearns R, Gonzalez-Flecha B. (2005). Lysosomal and mitochondrial pathwaysin H2O2-induced apoptosis of alveolar type II cells. J Cell Biochem 94: 433-445.
-
(2005)
J Cell Biochem
, vol.94
, pp. 433-445
-
-
Yin, L.1
Stearns, R.2
Gonzalez-Flecha, B.3
-
164
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
Youle RJ, Strasser A. (2008). The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9: 47-59.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
165
-
-
0141853870
-
3-aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes
-
Yu ZQ, Wei L, Brunk UT. (2003). 3-aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes. APMIS 111: 643-652.
-
(2003)
APMIS
, vol.111
, pp. 643-652
-
-
Yu, Z.Q.1
Wei, L.2
Brunk, U.T.3
-
166
-
-
0033950037
-
Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products
-
Yuan XM, Li W, Brunk UT, Dalen H, Chang YH, Sevanian A. (2000). Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products. Free Radic Biol Med 28: 208-218.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 208-218
-
-
Yuan, X.M.1
Li, W.2
Brunk, U.T.3
Dalen, H.4
Chang, Y.H.5
Sevanian, A.6
-
167
-
-
0037197938
-
Lysosomal destabilization in p53-induced apoptosis
-
Yuan XM, Li W, Dalen H, Lotem J, Kama R, Sachs L et al. (2002). Lysosomal destabilization in p53-induced apoptosis. Proc Natl Acad Sci USA 99: 6286-6291.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6286-6291
-
-
Yuan, X.M.1
Li, W.2
Dalen, H.3
Lotem, J.4
Kama, R.5
Sachs, L.6
-
168
-
-
17844362452
-
Bid acts on the permeability transition pore complex to induce apoptosis
-
Zamzami N, El Hamel C, Maisse C, Brenner C, Munoz-Pinedo C, Belzacq AS et al. (2000). Bid acts on the permeability transition pore complex to induce apoptosis. Oncogene 19: 6342-6350.
-
(2000)
Oncogene
, vol.19
, pp. 6342-6350
-
-
Zamzami, N.1
El Hamel, C.2
Maisse, C.3
Brenner, C.4
Munoz-Pinedo, C.5
Belzacq, A.S.6
-
169
-
-
0035018235
-
Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells
-
Zang Y, Beard RL, Chandraratna RA, Kang JX. (2001). Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells. Cell Death Differ 8: 477-485.
-
(2001)
Cell Death Differ
, vol.8
, pp. 477-485
-
-
Zang, Y.1
Beard, R.L.2
Chandraratna, R.A.3
Kang, J.X.4
-
170
-
-
0141447370
-
Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis
-
Zhao M, Antunes F, Eaton JW, Brunk UT. (2003). Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis. Eur J Biochem 270: 3778-3786.
-
(2003)
Eur J Biochem
, vol.270
, pp. 3778-3786
-
-
Zhao, M.1
Antunes, F.2
Eaton, J.W.3
Brunk, U.T.4
-
171
-
-
0035861903
-
Delayed oxidant-induced cell death involves activation of phospholipase A2
-
Zhao M, Brunk UT, Eaton JW. (2001a). Delayed oxidant-induced cell death involves activation of phospholipase A2. FEBS Lett 509: 399-404.
-
(2001)
FEBS Lett
, vol.509
, pp. 399-404
-
-
Zhao, M.1
Brunk, U.T.2
Eaton, J.W.3
-
172
-
-
0035861890
-
Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis
-
Zhao M, Eaton JW, Brunk UT. (2001b). Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis. FEBS Lett 509: 405-412.
-
(2001)
FEBS Lett
, vol.509
, pp. 405-412
-
-
Zhao, M.1
Eaton, J.W.2
Brunk, U.T.3
-
173
-
-
33845669080
-
Lysosomal cathepsins in embryonic programmed cell death
-
Zuzarte-Luis V, Montero JA, Kawakami Y, Izpisua-Belmonte JC, Hurle JM. (2007a). Lysosomal cathepsins in embryonic programmed cell death. Dev Biol 301: 205-217.
-
(2007)
Dev Biol
, vol.301
, pp. 205-217
-
-
Zuzarte-Luis, V.1
Montero, J.A.2
Kawakami, Y.3
Izpisua-Belmonte, J.C.4
Hurle, J.M.5
-
174
-
-
33947396061
-
Cathepsin D gene expression outlines the areas of physiological cell death during embryonic development
-
Zuzarte-Luis V, Montero JA, Torre-Perez N, Garcia-Porrero JA, Hurle JM. (2007b). Cathepsin D gene expression outlines the areas of physiological cell death during embryonic development. Dev Dyn 236: 880-885.
-
(2007)
Dev Dyn
, vol.236
, pp. 880-885
-
-
Zuzarte-Luis, V.1
Montero, J.A.2
Torre-Perez, N.3
Garcia-Porrero, J.A.4
Hurle, J.M.5
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