메뉴 건너뛰기




Volumn 111, Issue 6, 2003, Pages 643-652

3-Aminopropanal is a lysosomotropic aldehyde that causes oxidative stress and apoptosis by rupturing lysosomes

Author keywords

3 aminopropanal; Apoptosis; Lysosomes; Mitochondria; Oxidative stress

Indexed keywords

3 AMINOPROPANAL; ALDEHYDE; CASPASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

EID: 0141853870     PISSN: 09034641     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0463.2003.1110607.x     Document Type: Article
Times cited : (36)

References (44)
  • 1
    • 0017329684 scopus 로고
    • Clinical relevance of polyamines as biochemical markers of tumor kinetics
    • Russell DH. Clinical relevance of polyamines as biochemical markers of tumor kinetics. Clin Chem 1977;23:22-7.
    • (1977) Clin Chem , vol.23 , pp. 22-27
    • Russell, D.H.1
  • 2
    • 0034492094 scopus 로고    scopus 로고
    • Polyamines in human and animal milk
    • Loser C. Polyamines in human and animal milk. Br J Nutr 2000;84 Suppl 1:S55-8.
    • (2000) Br J Nutr , vol.84 , Issue.1 SUPPL.
    • Loser, C.1
  • 3
    • 0034126310 scopus 로고    scopus 로고
    • Oxidation of polyamines and brain injury
    • Seiler N. Oxidation of polyamines and brain injury. Neurochem Res 2000;25:471-90.
    • (2000) Neurochem Res , vol.25 , pp. 471-490
    • Seiler, N.1
  • 4
    • 0033949077 scopus 로고    scopus 로고
    • Spermine cytotoxicity to human colon carcinoma-derived cells (CaCo-2)
    • Seiler N, Duranton B, Gosse F, Raul F. Spermine cytotoxicity to human colon carcinoma-derived cells (CaCo-2). Cell Biol Toxicol 2000;16:117-30.
    • (2000) Cell Biol Toxicol , vol.16 , pp. 117-130
    • Seiler, N.1    Duranton, B.2    Gosse, F.3    Raul, F.4
  • 6
    • 0031824133 scopus 로고    scopus 로고
    • Cerebral ischemia enhances polyamine oxidation: Identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death
    • Ivanova S, Botchkina GI, Al-Abed Y, Meistrell M, 3rd, Batliwalla F, Dubinsky JM, et al. Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death. J Exp Med 1998;188:327-40.
    • (1998) J Exp Med , vol.188 , pp. 327-340
    • Ivanova, S.1    Botchkina, G.I.2    Al-Abed, Y.3    Meistrell M. III4    Batliwalla, F.5    Dubinsky, J.M.6
  • 8
    • 0026764463 scopus 로고
    • Implication of the polyamines in the neurotoxic effects of N-methyl-D-aspartate
    • Porcella A, Fage D, Voltz C, Bourdiol F, Benavides J, Scatton B, et al. Implication of the polyamines in the neurotoxic effects of N-methyl-D-aspartate. Neurol Res 1992;14:181-3.
    • (1992) Neurol Res , vol.14 , pp. 181-183
    • Porcella, A.1    Fage, D.2    Voltz, C.3    Bourdiol, F.4    Benavides, J.5    Scatton, B.6
  • 9
    • 0027471054 scopus 로고
    • Ornithine decarboxylase inhibition or NMDA receptor antagonism reduce cortical polyamine efflux associated with dialysis probe implantation
    • Fage D, Carboni S, Voltz C, Scatton B, Carter C. Ornithine decarboxylase inhibition or NMDA receptor antagonism reduce cortical polyamine efflux associated with dialysis probe implantation. Neurosci Lett 1993;149:173-6.
    • (1993) Neurosci Lett , vol.149 , pp. 173-176
    • Fage, D.1    Carboni, S.2    Voltz, C.3    Scatton, B.4    Carter, C.5
  • 10
    • 0038641715 scopus 로고    scopus 로고
    • 3-Aminopropanal, formed during cerebral ischemia, is a potent lysosomotropic neurotoxin
    • Li W, Yuan XM, Ivanova S, Tracey KJ, Eaton JW, Brunk UT. 3-Aminopropanal, formed during cerebral ischemia, is a potent lysosomotropic neurotoxin. Biochem J 2003;371:429-36.
    • (2003) Biochem J , vol.371 , pp. 429-436
    • Li, W.1    Yuan, X.M.2    Ivanova, S.3    Tracey, K.J.4    Eaton, J.W.5    Brunk, U.T.6
  • 12
    • 0029133790 scopus 로고
    • Cellular injury induced by oxidative stress is mediated through lysosomal damage
    • Öllinger K, Brunk UT. Cellular injury induced by oxidative stress is mediated through lysosomal damage. Free Radic Biol Med 1995;19:565-74.
    • (1995) Free Radic Biol Med , vol.19 , pp. 565-574
    • Öllinger, K.1    Brunk, U.T.2
  • 13
    • 0032988381 scopus 로고    scopus 로고
    • Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak
    • Brunk UT, Svensson I. Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak. Redox Rep 1999;4:3-11.
    • (1999) Redox Rep , vol.4 , pp. 3-11
    • Brunk, U.T.1    Svensson, I.2
  • 14
  • 15
    • 0035887215 scopus 로고    scopus 로고
    • Sphingosine-induced apoptosis is dependent on lysosomal proteases
    • Kågedal K, Zhao M, Svensson I, Brunk UT. Sphingosine-induced apoptosis is dependent on lysosomal proteases. Biochem J 2001;359:335-43.
    • (2001) Biochem J , vol.359 , pp. 335-343
    • Kågedal, K.1    Zhao, M.2    Svensson, I.3    Brunk, U.T.4
  • 17
    • 1842330849 scopus 로고    scopus 로고
    • Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
    • Garcia-Ruiz C, Colell A, Mari M, Morales A, Fernandez-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J Biol Chem 1997;272:11369-77.
    • (1997) J Biol Chem , vol.272 , pp. 11369-11377
    • Garcia-Ruiz, C.1    Colell, A.2    Mari, M.3    Morales, A.4    Fernandez-Checa, J.C.5
  • 18
    • 0031017999 scopus 로고    scopus 로고
    • Ex vivo induction of apoptosis in lymphocytes is mediated by oxidative stress: Role for lymphocyte loss in HIV infection
    • Dobmeyer TS, Findhammer S, Dobmeyer JM, Klein SA, Raffel B, Hoelzer D, et al. Ex vivo induction of apoptosis in lymphocytes is mediated by oxidative stress: role for lymphocyte loss in HIV infection. Free Radic Biol Med 1997;22:775-85.
    • (1997) Free Radic Biol Med , vol.22 , pp. 775-785
    • Dobmeyer, T.S.1    Findhammer, S.2    Dobmeyer, J.M.3    Klein, S.A.4    Raffel, B.5    Hoelzer, D.6
  • 20
    • 0141491449 scopus 로고    scopus 로고
    • Relocation of lysosomal enzymes induces mitochondria-mediated oxidative stress, release of cytochrome c, and apoptosis
    • submitted
    • Zhao M, Antunes F, Eaton JW, Brunk UT. Relocation of lysosomal enzymes induces mitochondria-mediated oxidative stress, release of cytochrome c, and apoptosis. Eur J Biochem (submitted).
    • Eur J Biochem
    • Zhao, M.1    Antunes, F.2    Eaton, J.W.3    Brunk, U.T.4
  • 21
    • 0025070370 scopus 로고
    • Photooxidative damage to lysosomes of cultured macrophages by acridine orange
    • Zdolsek JM, Olsson GM, Brunk UT. Photooxidative damage to lysosomes of cultured macrophages by acridine orange. Photochem Photobiol 1990;51:67-76.
    • (1990) Photochem Photobiol , vol.51 , pp. 67-76
    • Zdolsek, J.M.1    Olsson, G.M.2    Brunk, U.T.3
  • 22
    • 0033198273 scopus 로고    scopus 로고
    • Mitochondrial depolarization is not required for neuronal apoptosis
    • Krohn AJ, Wahlbrink T, Prehn JH. Mitochondrial depolarization is not required for neuronal apoptosis. J Neurosci 1999;19:7394-404.
    • (1999) J Neurosci , vol.19 , pp. 7394-7404
    • Krohn, A.J.1    Wahlbrink, T.2    Prehn, J.H.3
  • 25
    • 0035408169 scopus 로고    scopus 로고
    • The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress
    • Kågedal K, Johansson U, Öllinger K. The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress. Faseb J 2001;15:1592-4.
    • (2001) Faseb J , vol.15 , pp. 1592-1594
    • Kågedal, K.1    Johansson, U.2    Öllinger, K.3
  • 26
    • 0035793580 scopus 로고    scopus 로고
    • Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route
    • Stoka V, Turk B, Schendel SL, Kim TH, Cirman T, Snipas SJ, et al. Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route. J Biol Chem 2001;276:3149-57.
    • (2001) J Biol Chem , vol.276 , pp. 3149-3157
    • Stoka, V.1    Turk, B.2    Schendel, S.L.3    Kim, T.H.4    Cirman, T.5    Snipas, S.J.6
  • 27
    • 0033436344 scopus 로고    scopus 로고
    • Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress
    • Roberg K, Johansson U, Öllinger K. Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress. Free Radic Biol Med 1999;27:1228-37.
    • (1999) Free Radic Biol Med , vol.27 , pp. 1228-1237
    • Roberg, K.1    Johansson, U.2    Öllinger, K.3
  • 28
    • 0034650786 scopus 로고    scopus 로고
    • Inhibition of cathepsin D prevents free-radical-induced apoptosis in rat cardiomyocytes
    • Öllinger K. Inhibition of cathepsin D prevents free-radical-induced apoptosis in rat cardiomyocytes. Arch Biochem Biophys 2000;373:346-51.
    • (2000) Arch Biochem Biophys , vol.373 , pp. 346-351
    • Öllinger, K.1
  • 29
    • 0036935045 scopus 로고    scopus 로고
    • IL-11 pretreatment reduces cell death after intestinal ischemia-reperfusion
    • Kuenzler KA, Pearson PY, Schwartz MZ. IL-11 pretreatment reduces cell death after intestinal ischemia-reperfusion. J Surg Res 2002;108:268-72.
    • (2002) J Surg Res , vol.108 , pp. 268-272
    • Kuenzler, K.A.1    Pearson, P.Y.2    Schwartz, M.Z.3
  • 30
    • 0021750856 scopus 로고
    • Comparison of live human neutrophil and alveolar macrophage elastolytic activity in vitro. Relative resistance of macrophage elastolytic activity to serum and alveolar proteinase inhibitors
    • Chapman HA Jr, Stone OL. Comparison of live human neutrophil and alveolar macrophage elastolytic activity in vitro. Relative resistance of macrophage elastolytic activity to serum and alveolar proteinase inhibitors. J Clin Invest 1984;74:1693-700.
    • (1984) J Clin Invest , vol.74 , pp. 1693-1700
    • Chapman H.A., Jr.1    Stone, O.L.2
  • 31
    • 0028942799 scopus 로고
    • The septoclast, a cathepsin B-rich cell involved in the resorption of growth plate cartilage
    • Lee ER, Lamplugh L, Shepard NL, Mort JS. The septoclast, a cathepsin B-rich cell involved in the resorption of growth plate cartilage. J Histochem Cytochem 1995;43:525-36.
    • (1995) J Histochem Cytochem , vol.43 , pp. 525-536
    • Lee, E.R.1    Lamplugh, L.2    Shepard, N.L.3    Mort, J.S.4
  • 32
    • 0023870493 scopus 로고
    • Clastogenic and cytotoxic effects of spermine oxidation products in mouse lymphoma L5178Y cells
    • Bouzyk E, Rosiek O. Clastogenic and cytotoxic effects of spermine oxidation products in mouse lymphoma L5178Y cells. Cancer Lett 1988;39:93-9.
    • (1988) Cancer Lett , vol.39 , pp. 93-99
    • Bouzyk, E.1    Rosiek, O.2
  • 33
    • 0021164308 scopus 로고
    • Polyamine oxidase-mediated trypanosome killing: The role of hydrogen peroxide and aldehydes
    • Ferrante A, Rzepczyk CM, Saul AJ. Polyamine oxidase-mediated trypanosome killing: the role of hydrogen peroxide and aldehydes. J Immunol 1984;133:2157-62.
    • (1984) J Immunol , vol.133 , pp. 2157-2162
    • Ferrante, A.1    Rzepczyk, C.M.2    Saul, A.J.3
  • 36
    • 0036423710 scopus 로고    scopus 로고
    • On the release of cytochrome c from mitochondria during cell death signaling
    • Lim ML, Lum MG, Hansen TM, Roucou X, Nagley P. On the release of cytochrome c from mitochondria during cell death signaling. J Biomed Sci 2002;9:488-506.
    • (2002) J Biomed Sci , vol.9 , pp. 488-506
    • Lim, M.L.1    Lum, M.G.2    Hansen, T.M.3    Roucou, X.4    Nagley, P.5
  • 37
    • 0037119563 scopus 로고    scopus 로고
    • The role of the mitochondrial permeability transition pore in neurodegenerative processes
    • Tornero D, Cena V, Gonzalez-Garcia C, Jordan J. The role of the mitochondrial permeability transition pore in neurodegenerative processes. Rev Neurol 2002;35:354-61.
    • (2002) Rev Neurol , vol.35 , pp. 354-361
    • Tornero, D.1    Cena, V.2    Gonzalez-Garcia, C.3    Jordan, J.4
  • 39
    • 0034745672 scopus 로고    scopus 로고
    • Relocalization of cathepsin D and cytochrome c early in apoptosis revealed by immunoelectron microscopy
    • Roberg K. Relocalization of cathepsin D and cytochrome c early in apoptosis revealed by immunoelectron microscopy. Lab Invest 2001;81:149-58.
    • (2001) Lab Invest , vol.81 , pp. 149-158
    • Roberg, K.1
  • 40
    • 0035861903 scopus 로고    scopus 로고
    • Delayed oxidant-induced cell death involves activation of phospholipase A2
    • Zhao M, Brunk UT, Eaton JW. Delayed oxidant-induced cell death involves activation of phospholipase A2. FEBS Lett 2001;509:399-404.
    • (2001) FEBS Lett , vol.509 , pp. 399-404
    • Zhao, M.1    Brunk, U.T.2    Eaton, J.W.3
  • 41
    • 0035038613 scopus 로고    scopus 로고
    • Triggering of apoptosis by cathepsins
    • Leist M, Jäättelä M. Triggering of apoptosis by cathepsins. Cell Death Differ 2001;8:324-6.
    • (2001) Cell Death Differ , vol.8 , pp. 324-326
    • Leist, M.1    Jäättelä, M.2
  • 42
    • 0035947776 scopus 로고    scopus 로고
    • Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor
    • Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, et al. Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 2001;153:999-1010.
    • (2001) J Cell Biol , vol.153 , pp. 999-1010
    • Foghsgaard, L.1    Wissing, D.2    Mauch, D.3    Lademann, U.4    Bastholm, L.5    Boes, M.6
  • 43
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner MO. The biochemistry of apoptosis. Nature 2000;407:770-6.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 44
    • 0035451525 scopus 로고    scopus 로고
    • Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death?
    • Hancock JT, Desikan R, Neill SJ. Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death? Free Radic Biol Med 2001;31:697-703.
    • (2001) Free Radic Biol Med , vol.31 , pp. 697-703
    • Hancock, J.T.1    Desikan, R.2    Neill, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.