Cathepsin B is involved in the apoptosis intrinsic pathway induced by Bacillus Calmette-Guérin in transitional cancer cell lines

International Journal of Molecular Medicine

Volumn 20, Issue 6, 2007, Pages 823-828

  Sandes, Eduardo ^a   Lodillinsky, Catalina ^a   Cwirenbaum, Ruth ^a   Argüelles, Claudia ^b   Casabé, Alberto ^a   Eiján, Ana María ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Instituto Nacional de Producción de Biológicos Dr Carlos G Malbrán ^*  (Argentina)

Author keywords

Apoptosis; Bacillus Calmette Gu rin; Bladder cancer; Cathepsin B; Transitional cancer cell

Indexed keywords

BCG VACCINE; CASPASE 9; CATHEPSIN B; PROTEIN BID; PROTEIN PRECURSOR;

ANIMAL; APOPTOSIS; ARTICLE; BLADDER TUMOR; CELL CULTURE; ENZYME ACTIVATION; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSITIONAL CELL CARCINOMA;

ANIMALS; APOPTOSIS; BCG VACCINE; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARCINOMA, TRANSITIONAL CELL; CASPASE 9; CATHEPSIN B; ENZYME ACTIVATION; HUMANS; PROTEIN PRECURSORS; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 42149092670     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.20.6.823     Document Type: Article

References (28)

1. Malkowicz SB: Intravesical therapy for superficial bladder cancer. Semin Urol Oncol 18: 280-288, 2000.
2. Sylvester RJ, van der Meijden AP and Lamm DL: Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: a meta-analysis of the published results of randomized clinical trials. J Urol 168: 1964-1970, 2002.
3. Davis JW, Sheth SI, Doviak MJ and Schellhammer PF: Superficial bladder carcinoma treated with bacillus Calmette-Guerin: progression-free and disease specific survival with minimum 10-year follow up. J Urol 167: 494-500, 2002.
4. Suttmann H, Jacobsen M, Reiss K, Jocham D, Bohle A and Brandau S: Mechanisms of bacillus Calmette Guérin mediated natural killer cell activation. J Urol 172: 1490-1495, 2004.
5. Becich MJ, Carroll S and Ratliff TL: Internalization of bacilli Calmette-Guérin by bladder tumor cells. J Urol 145: 1316-1324, 1991.
6. Ikeda N, Toida I, Iwasaki A, Kawai K and Akaza H: Surface antigen expression on bladder tumor cells induced by bacillus Calmette-Guérin (BCG): A role of BCG internalization into tumor cells. Int J Urol 9: 29-35, 2002.
7. Alvarez V, Lodillinsky C, Umerez S, Sandes E and Eiján AM: Inhibition of bacillus Calmette-Guérin induced nitric oxide in bladder tumor cells may improve BCG treatment. Int J Mol Med 16: 565-571, 2005.
8. Riendeau C and Kornfeld H: THP1 cell apoptosis in response to Mycobacterial infection. Infect Immun 71: 254-259, 2003. (Pubitemid 36026027)
9. Weinrauch Y and Zychlinsky A: The induction of apoptosis by bacterial pathogens. Annu Rev Microbiol 53: 155-187, 1999.
10. Papageorgiou A, Lashinger L, Millikan R, Grossman HB, Benedict W, Dinney CP and McConkey DJ: Role of tumor necrosis factor-related apoptosis-inducing ligand in interferon-induced apoptosis in human bladder cancer cells. Cancer Res 64: 8973-8979, 2004.
11. Jäättelä M: Multiple cell death pathways as regulators of tumour initiation and progression. Oncogene 23: 2746-2756, 2004.
12. Jin Z and El-Deiry WS: Overview of cell death signaling pathways. Cancer Biol Ther 4: 139-163, 2005.
13. Guicciardi ME, Leist M and Gores GJ: Lysosomes in cell death. Oncogene 23: 2881-2890, 2004.
14. Foghsgaard L, Wissing D, Mauch D, Lademann U, Bastholm L, Boes M, Elling FM, Leist M and Jäätteelä M: Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biology 153: 999-1010, 2001.
15. Lamparska-Przybysz M, Gajkowska B and Motyl T: Cathepsins and BID are involved in the molecular switch between apoptosis and autophagy in breast cancer MCF-7 cells exposed to camptothecin. J Physiol Pharmacol 56: 159-179, 2005.
16. Eiján AM, Sandes EO, Riveros MD, Thompson S, Pasik L, Malagrino H, Celeste F and Casabé AR: High expression of cathepsin B in transitional bladder cancer correlates with tumor invasion. Cancer 98: 262-268, 2003.
17. Laemmli UK: Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
18. Barrett AJ and Kirschke H: Cathepsin B, cathepsin H and cathepsin L. Methods Enzymol 80: 535-561, 1981.
19. + T cell immunity against B16 melanome. J Immunol 171: 5940-5947, 2003.
20. Albert ML, Sauter B and Bhardwaj N: Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392: 86-89, 1998.
21. Pook SH, Esuvaranathan K and Mahendran R: N-acetylcysteine augments the cellular redox changes and cytotoxic activity of int-ernalized mycobacterium bovis in human bladder cancer cells. J Urol 168: 780-785, 2002.
22. Deussing J, Roth W, Saftig P, Peters C, Ploegh H and Villadangos JA: Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation. Proc Natl Acad Sci USA 95: 4516-4521, 1998. (Pubitemid 28207944)
23. Buttle DJ, Murata M, Knight CG and Barrett AJ: CA074methyl ester: a proinhibitor for intracellular cathepsin B. Arch Biochem Biophys 299: 377-380, 1992.
24. Filion MC, Lépicier P, Morales A and Phillips NC: Mycobacterium phlei cell wall complex directly induces apoptosis in human bladder cancer cells. Br J Cancer 79: 229-235, 1999.
25. Danial N and Korsmeyer SJ: Cell death: Critical control points. Cell 116: 205-219, 2004.
26. Guicciardi ME, Deussing J, Miyoshi H, Bronk SF, Svingen PA, Peters C, Kaufmann SH and Gores GJ: Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J Clin Invest 106: 1127-1137, 2000.
27. Enoksson M, Robertson JD, Gogvadze V, Bu P, Kropotov A, Zhivotovsky B and Orrenius S: Caspase-2 permeabilizes the outer mitochondrial membrane and disrupts the binding of cytochrome c to anionic phospholipids. J Biol Chem 279: 49575-49578, 2004.
28. Yeung BH, Huang DC and Sinicrope FA: PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells. J Biol Chem 281: 11923-11932, 2006.