Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis

European Journal of Biochemistry

Volumn 270, Issue 18, 2003, Pages 3778-3786

  Zhao, Ming ^a   Antunes, Fernando ^a,b   Eaton, John W ^a,c   Brunk, Ulf T ^a  

^a LINKÖPING UNIVERSITY   (Sweden)

^b UNIVERSITY OF LISBON   (Portugal)

^c UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

Apoptosis; Cathepsins; Lysosomes; Lysosomotropic detergents; Oxidative stress

Indexed keywords

CATHEPSIN B; CATHEPSIN D; CYTOCHROME C; DETERGENT; LYSOSOME ENZYME; O METHYLSERINE DODECYLAMIDE; PHOSPHOLIPASE A2; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; FIBROBLAST; HELA CELL; HUMAN; HUMAN CELL; LYSOSOME; MACROPHAGE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REACTOR CASCADE;

AMIDES; ANIMALS; APOPTOSIS; CATHEPSINS; CELL LINE; CYTOCHROME C GROUP; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; LYSOSOMES; MACROPHAGES; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA, LIVER; OXIDATIVE STRESS; PHOSPHOLIPASES A; RATS; RATS, SPRAGUE-DAWLEY; SERINE; STRESS FIBERS; SUPEROXIDES;

ANIMALIA; MAMMALIA;

EID: 0141447370     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03765.x     Document Type: Article

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