Engulfment Is Required for Cell Competition

Cell

Volumn 129, Issue 6, 2007, Pages 1215-1225

  Li, Wei ^a   Baker, Nicholas E ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

CELLBIO

Indexed keywords

MEMBRANE RECEPTOR; PHOSPHATIDYLSERINE; RECEPTOR; RIBOSOME PROTEIN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL GROWTH; DOCK180 GENE; DRAPER GENE; DROSOPHILA; EMBRYO DEVELOPMENT; GENE; GENE DOSAGE; GENE MUTATION; GENOTYPE; MBC GENE; NONHUMAN; ONCOGENE MYC; PRIORITY JOURNAL; RAC1 GENE; RIBOSOME; WASP GENE;

EID: 34250025633     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2007.03.054     Document Type: Article

References (63)

1. Abrams J.M., White K., Fessler L.I., and Steller H. Programmed cell death during Drosophila embryogenesis. Development 117 (1993) 29-43
2. Awasaki T., Tatsumi R., Takahashi K., Arai K., Nakanishi Y., Ueda R., and Ito K. Essential role of the apoptotic cell engulfment genes draper and ced-6 in programmed axon pruning during Drosophila metamorphosis. Neuron 50 (2006) 855-867
3. Baker B.S., and Belote J.M. Sex determination and dosage compensation in Drosophila melanogaster. Annu. Rev. Genet. 17 (1983) 345-393
4. Bogdan S., and Klambt C. Kette regulates actin dynamincs and genetically interacts with Wave and Wasp. Development 130 (2003) 4427-4437
5. Boring L.F., Sinervo B., and Schubiger G. Experimental phenocopy of a Minute maternal-effect mutation alters blastoderm determination in embryos of Drosophila melanogaster. Dev. Biol. 132 (1989) 343-354
6. Cikala M., Alexandrova O., David C., Proschel M., Stiening B., Cramer P., and Bottger A. The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity. BMC Cell Biol. 5 (2004) 26
7. Cohen S.M. Imaginal disc development. In: Bate M., and Martinez Arias A. (Eds). The Development of Drosophila melanogaster (1993), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 747-841
8. Cui P., Qin B., Liu N., Pan G., and Pei D. Nuclear localization of the phosphatidylserine receptor protein via multiple nuclear localization signals. Exp. Cell Res. 293 (2004) 154-163
9. de Celis J.F., Barrio R., and Kafatos F.C. A gene complex acting downstream of dpp in Drosophila wing morphogenesis. Nature 381 (1996) 421-424
10. de la Cova C., Abril M., Bellosta P., Gallant P., and Johnston L.A. Drosophila Myc regulates organ size by inducing cell competition. Cell 117 (2004) 107-116
11. Edgar B.A. From cell structure to transcription: Hippo forges a new path. Cell 124 (2006) 267-273
12. van den Eijnde S.M., Boshart L., Baehrecke E.H., De Zeeuw C.I., Reutelingsperger C.P., and Vermeij-Keers C. Cell surface exposure of phosphatidylserine during apoptosis is phylogenetically conserved. Apoptosis 3 (1998) 9-16
13. Fadok V., Voelker D., Campbell P., Cohen J., Bratton D., and Henson P. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J. Immunol. 148 (1992) 2207-2216
14. Fadok V.A., Bratton D.L., Rose D.M., Pearson A., Ezekewitz R.A.B., and Henson P.M. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 405 (2000) 85-90
15. Firth L.C., Li W., Zhang H., and Baker N.E. Analyses of RAS regulation of eye development in Drosophila melanogaster. Methods Enzymol. 407 (2006) 711-721
16. Franc N.C., Heitzler P., Ezekowitz R.A., and White K. Requirement for croquemort in phagocytosis of apoptotic cells in Drosophila. Science 284 (1999) 1991-1994
17. Franc N.C., White K., and Ezekewitz R.A. Phagocytosis and development: back to the future. Curr. Opin. Immunol. 11 (1999) 47-52
18. Freeman M.R., Delrow J., Kim J., Johnson E., and Doe C.Q. Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and function. Neuron 38 (2003) 567-580
19. Fristrom D. Cellular degeneration in the production of some mutant phenotypes in Drosophila melanogaster. Mol. Gen. Genet. 103 (1969) 363-379
20. Garcia-Bellido A., Ripoll P., and Morata G. Developmental compartmentalisation of the wing disk of Drosophila. Nat. New Biol. 245 (1973) 251-253
21. Gibson M.C., and Perrimon N. Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing. Science 307 (2005) 1785-1789
22. Hay B., Wolff T., and Rubin G. Expression of baculovirus P35 prevents cell death in Drosophila. Development 120 (1994) 2121-2129
23. Hoeppner D.J., Hengartner M.O., and Schnabel R. Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans. Nature 412 (2001) 202-206
24. Hong J.-R., Lin G.-H., Lin C.J.-F., Wang W.-p., Lee C.-C., Lin T.-L., and Wu J.-L. Phosphatidylserine receptor is required for the engulfment of dead apoptotic cells and for normal embryonic development in zebrafish. Development 131 (2004) 5417-5427
25. Huh J.R., Guo M., and Hay B.A. Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role. Curr. Biol. 14 (2004) 1262-1266
26. Kinchen J.M., Cabello J., Klingele D., Wong K., Feichtinger R., Schnabel H., Schnabel R., and Hengartner M.O. Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans. Nature 434 (2005) 93-99
27. Lambertsson A. The Minute genes in Drosophila and their molecular functions. Adv. Genet. 38 (1998) 69-134
28. Lee T., and Luo L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 22 (1999) 451-461
29. Li M.O., Sarkisian M.R., Mehal W.Z., Rakic P., and Flavell R.A. Phosphatidylserine receptor is required for clearance of apoptotic cells. Science 302 (2003) 1560-1563
30. Lorenzi R., Brickell P.M., Katz D.R., Kinnon C., and Thrasher A.J. Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis. Blood 95 (2000) 2943-2946
31. MacDonald J.M., Beach M.G., Porpiglia E., Sheehan A.E., Watts R.J., and Freeman M.R. The Drosophila cell corpse engulfment receptor draper mediates glial clearance of severed axons. Neuron 50 (2006) 869-881
32. Manaka J., Kuraishi T., Shiratsuchi A., Nakai Y., Higashida H., Henson P., and Nakanishi Y. Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages. J. Biol. Chem. 279 (2004) 48466-48476
33. Martin S., Reutelingsperger C., McGahon A., Rader J., van Schie R., LaFace D., and Green D. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182 (1995) 1545-1556
34. Mitchell J.E., Cvetanovic M., Tibrewal N., Patel V., Colamonici O.R., Li M.O., Flavell R.A., Levine J.S., Birge R.B., and Ucker D.S. The presumptive phosphatidylserine receptor is dispensable for innate anti-inflammatory recognition and clearance of apoptotic cells. J. Biol. Chem. 281 (2006) 5718-5725
35. Morata G., and Ripoll P. Minutes: Mutants of Drosophila autonomously affecting cell division rate. Dev. Biol. 42 (1975) 211-221
36. Moreno E., and Basler K. dMyc transforms cells into super-competitors. Cell 117 (2004) 117-129
37. Moreno E., Basler K., and Morata G. Cells compete for Decapentaplegic survival factor to prevent apoptosis in Drosophila wing development. Nature 416 (2002) 755-759
38. Nesbit C.E., Tersak J.M., and Prochownik E.V. MYC oncogenes and human neoplastic disease. Oncogene 18 (1999) 3004-3016
39. Neufeld T.P., de la Cruz A.F.A., Johnston L.A., and Edgar B.A. Coordination of growth and cell division in the Drosophila wing. Cell 93 (1998) 1183-1193
40. Newsome T., Asling B., and Dickson B. Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development 127 (2000) 851-860
41. Nolan K.M., Barrett K., Lu Y., Hu K.Q., Vincent S., and Settleman J. Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Genes Dev 12 (1998) 3337-3342
42. Oertel M., Menthena A., Dabeva M.D., and Shafritz D.A. Cell competition leads to a high level of normal liver reconstitution by transplanted fetal liver stem/progenitor cells. Gastroenterology 130 (2006) 507-520
43. Oliver E.R., Saunders T.L., Tarle S.A., and Glaser T. Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse Minute. Development 131 (2004) 3907-3920
44. Pearson A.M., Baksa K., Ramet M., Protas M., McKee M., Brown D., and Ezekowitz R.A.B. Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila. Microbes Infect. 5 (2003) 815-824
45. Perez-Garijo A., Martin F.A., and Morata G. Caspase inhibition during apoptosis causes abnormal signalling and developmental abnormalities in Drosophila. Development 131 (2004) 5591-5598
46. Reddien P.W., and Horvitz H.R. CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans. Nat. Cell Biol. 2 (2000) 131-136
47. Reddien P.W., and Horvitz H.R. The engulfment process of programmed cell death in Caenorhabditis elegans. Annu. Rev. Cell Dev. Biol. 20 (2004) 193-221
48. Reddien P.W., Cameron S., and Horvitz H.R. Phagocytosis promotes programmed cell death in C. elegans. Nature 412 (2001) 198-202
49. Rosenblatt J., Raff M.C., and Cramer L.P. An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism. Curr. Biol. 11 (2001) 1847-1857
50. Ryoo H.D., Gorenc T., and Steller H. Apoptotic cells can induce compensatory proliferation through the JNK and the Wingless signaling pathways. Dev. Cell 7 (2004) 491-501
51. Shen J., and Dahmann C. Extrusion of cells with inappropriate Dpp signaling from Drosophila wing disc epithelia. Science 307 (2005) 1789-1790
52. Simpson P. Parameters of cell competition in the compartments of the wing disc of Drosophila. Dev. Biol. 69 (1979) 182-193
53. Simpson P., and Morata G. Differential mitotic rates and patterns of growth in compartments in the Drosophila wing. Dev. Biol. 85 (1981) 299-308
54. Tanimoto H., Itoh S., ten Dijke P., and Tabata T. Hedgehog creates a gradient of DPP activity in Drosophila wing imaginal discs. Mol. Cell 5 (2000) 59-71
55. Tepass U., Fessler L.I., Aziz A., and Hartenstein V. Embryonic origin of hemocytes and their relationship to cell death in Drosophila. Development 120 (1994) 1829-1837
56. Tyler D., Li W., Zhuo N., Pellock B., and Baker N.E. Genes affecting cell competition in Drosophila. Genetics 175 (2007) 645-657
57. Verhoven B., Schlegel R., and Williamson P. Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes. J. Exp. Med. 182 (1995) 1597-1601
58. Vidal M., Larson D.E., and Cagan R.L. Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis. Dev. Cell 10 (2006) 33-44
59. Wang X., Wu Y.-C., Fadok V.A., Lee M.-C., Gengyo-Ando K., Cheng L.-C., Ledwich D., Hsu P.-K., Chen J.-Y., Chou B.-K., et al. Cell corpse engulfment mediated by C. elegans Phosphatidylserine Receptor through CED-5 and CED-12. Science 302 (2003) 1563-1566
60. Wu Y.C., and Horvitz H.R. C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392 (1998) 501-504
61. Xu T., and Rubin G. Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117 (1993) 1223-1237
62. Zhang J., Shehabeldin A., da Cruz L.A.G., Butler J., Somani A.-K., McGavin M., Kozieradzki I., dos Santos A.O., Nagy A., Grinstein S., et al. Antigen receptor-induced activation and cytoskeletal rearrangement are Impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes. J. Exp. Med. 190 (1999) 1329-1342
63. Zhou Z., Hartweig E., and Horvitz H.R. CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans. Cell 104 (2001) 43-56