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Volumn 44, Issue 7, 2008, Pages 1246-1258

Silica binding and toxicity in alveolar macrophages

Author keywords

Free radicals; Immune modulation; Macrophage; MARCO; Scavenger receptor; Silica; SR A

Indexed keywords

CELL SURFACE RECEPTOR; LUNG SURFACTANT; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SCAVENGER; SCAVENGER RECEPTOR; SILICON DIOXIDE;

EID: 40949129640     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.12.027     Document Type: Review
Times cited : (326)

References (120)
  • 1
    • 0022650880 scopus 로고
    • The pathogenesis of silicosis: state of the art
    • Davis G.S. The pathogenesis of silicosis: state of the art. Chest 89 (1986) 166S-169S
    • (1986) Chest , vol.89
    • Davis, G.S.1
  • 6
    • 33745617141 scopus 로고    scopus 로고
    • Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005
    • Pelucchi C., Pira E., Piolatto G., Coggiola M., Carta P., and La Vecchia C. Occupational silica exposure and lung cancer risk: a review of epidemiological studies 1996-2005. Ann. Oncol. 17 (2006) 1039-1050
    • (2006) Ann. Oncol. , vol.17 , pp. 1039-1050
    • Pelucchi, C.1    Pira, E.2    Piolatto, G.3    Coggiola, M.4    Carta, P.5    La Vecchia, C.6
  • 7
    • 0030308101 scopus 로고    scopus 로고
    • Significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles
    • (Suppl.)
    • Oberdorster G. Significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles. Inhal. Toxicol. 8 (1996) 73-89 (Suppl.)
    • (1996) Inhal. Toxicol. , vol.8 , pp. 73-89
    • Oberdorster, G.1
  • 8
    • 0027358072 scopus 로고
    • How silicosis and coal workers' pneumoconiosis develop-a cellular assessment
    • Lapp N.L., and Castranova V. How silicosis and coal workers' pneumoconiosis develop-a cellular assessment. Occup. Med. 8 (1993) 35-56
    • (1993) Occup. Med. , vol.8 , pp. 35-56
    • Lapp, N.L.1    Castranova, V.2
  • 9
    • 18944383251 scopus 로고    scopus 로고
    • Increase in a distinct pulmonary macrophage subset possessing an antigen-presenting cell phenotype and in vitro APC activity following silica exposure
    • Migliaccio C.T., Hamilton Jr. R.F., and Holian A. Increase in a distinct pulmonary macrophage subset possessing an antigen-presenting cell phenotype and in vitro APC activity following silica exposure. Toxicol. Appl. Pharmacol. 205 (2005) 168-176
    • (2005) Toxicol. Appl. Pharmacol. , vol.205 , pp. 168-176
    • Migliaccio, C.T.1    Hamilton Jr., R.F.2    Holian, A.3
  • 10
    • 0025869846 scopus 로고
    • Comparison of alveolar and interstitial macrophages in fibroblast stimulation after silica and long or short asbestos
    • Adamson I.Y., Letourneau H.L., and Bowden D.H. Comparison of alveolar and interstitial macrophages in fibroblast stimulation after silica and long or short asbestos. Lab. Invest. 64 (1991) 339-344
    • (1991) Lab. Invest. , vol.64 , pp. 339-344
    • Adamson, I.Y.1    Letourneau, H.L.2    Bowden, D.H.3
  • 11
    • 0024514465 scopus 로고
    • Silica-induced pulmonary fibrosis involves the reaction of particles with interstitial rather than alveolar macrophages
    • Bowden D.H., Hedgecock C., and Adamson I.Y. Silica-induced pulmonary fibrosis involves the reaction of particles with interstitial rather than alveolar macrophages. J. Pathol. 158 (1989) 73-80
    • (1989) J. Pathol. , vol.158 , pp. 73-80
    • Bowden, D.H.1    Hedgecock, C.2    Adamson, I.Y.3
  • 12
    • 0017700949 scopus 로고
    • Changes in pulmonary surfactant and phosphatidylcholine metabolism in rats exposed to chrysotile asbestos dust
    • Tetley T.D., Richards R.J., and Harwood J.L. Changes in pulmonary surfactant and phosphatidylcholine metabolism in rats exposed to chrysotile asbestos dust. Biochem. J. 166 (1977) 323-329
    • (1977) Biochem. J. , vol.166 , pp. 323-329
    • Tetley, T.D.1    Richards, R.J.2    Harwood, J.L.3
  • 13
    • 0021603026 scopus 로고
    • Effect of silica and volcanic ash on the content of lung alveolar and tissue phospholipids
    • Kornbrust D.J., and Hatch G.E. Effect of silica and volcanic ash on the content of lung alveolar and tissue phospholipids. Environ. Res. 35 (1984) 140-153
    • (1984) Environ. Res. , vol.35 , pp. 140-153
    • Kornbrust, D.J.1    Hatch, G.E.2
  • 14
    • 0031661216 scopus 로고    scopus 로고
    • Effect of air pollutants on the pulmonary surfactant system
    • Muller B., Seifart C., and Barth P.J. Effect of air pollutants on the pulmonary surfactant system. Eur. J. Clin. Invest. 28 (1998) 762-777
    • (1998) Eur. J. Clin. Invest. , vol.28 , pp. 762-777
    • Muller, B.1    Seifart, C.2    Barth, P.J.3
  • 15
    • 0027997057 scopus 로고
    • Changes in alveolar lavage materials and lung microsomal xenobiotic metabolism following exposures to HCl-washed or unwashed crystalline silica
    • Miles P.R., Bowman L., Jones W.G., Berry D.S., and Vallyathan V. Changes in alveolar lavage materials and lung microsomal xenobiotic metabolism following exposures to HCl-washed or unwashed crystalline silica. Toxicol. Appl. Pharmacol. 129 (1994) 235-242
    • (1994) Toxicol. Appl. Pharmacol. , vol.129 , pp. 235-242
    • Miles, P.R.1    Bowman, L.2    Jones, W.G.3    Berry, D.S.4    Vallyathan, V.5
  • 16
    • 0029561447 scopus 로고
    • Altered regulation of surfactant phospholipid and protein A during acute pulmonary inflammation
    • Viviano C.J., Bakewell W.E., Dixon D., Dethloff L.A., and Hook G.E. Altered regulation of surfactant phospholipid and protein A during acute pulmonary inflammation. Biochim. Biophys. Acta 1259 (1995) 235-244
    • (1995) Biochim. Biophys. Acta , vol.1259 , pp. 235-244
    • Viviano, C.J.1    Bakewell, W.E.2    Dixon, D.3    Dethloff, L.A.4    Hook, G.E.5
  • 17
    • 0038779340 scopus 로고    scopus 로고
    • Investigations on the inflammatory and genotoxic lung effects of two types of titanium dioxide: untreated and surface treated
    • Rehn B., Seiler F., Rehn S., Bruch J., and Maier M. Investigations on the inflammatory and genotoxic lung effects of two types of titanium dioxide: untreated and surface treated. Toxicol. Appl. Pharmacol. 189 (2003) 84-95
    • (2003) Toxicol. Appl. Pharmacol. , vol.189 , pp. 84-95
    • Rehn, B.1    Seiler, F.2    Rehn, S.3    Bruch, J.4    Maier, M.5
  • 18
    • 0035798825 scopus 로고    scopus 로고
    • Significant differences in the cellular and molecular reactions of rat and hamster lung after quartz exposure
    • Seiler F., Rehn B., Rehn S., and Bruchs J. Significant differences in the cellular and molecular reactions of rat and hamster lung after quartz exposure. Toxicol. Lett. 119 (2001) 11-19
    • (2001) Toxicol. Lett. , vol.119 , pp. 11-19
    • Seiler, F.1    Rehn, B.2    Rehn, S.3    Bruchs, J.4
  • 19
    • 0034623936 scopus 로고    scopus 로고
    • Pulmonary surfactant proteins A and D are potent endogenous inhibitors of lipid peroxidation and oxidative cellular injury
    • Bridges J.P., Davis H.W., Damodarasamy M., Kuroki Y., Howles G., Hui D.Y., and McCormack F.X. Pulmonary surfactant proteins A and D are potent endogenous inhibitors of lipid peroxidation and oxidative cellular injury. J. Biol. Chem. 275 (2000) 38848-38855
    • (2000) J. Biol. Chem. , vol.275 , pp. 38848-38855
    • Bridges, J.P.1    Davis, H.W.2    Damodarasamy, M.3    Kuroki, Y.4    Howles, G.5    Hui, D.Y.6    McCormack, F.X.7
  • 22
    • 21544447246 scopus 로고    scopus 로고
    • Exposure to crystalline silica or treatment with chlorphentermine increases vitamin E levels in rat alveolar lavage materials
    • Miles P.R., Bowman L., and Reasor M.J. Exposure to crystalline silica or treatment with chlorphentermine increases vitamin E levels in rat alveolar lavage materials. J. Toxicol. Environ. Health 49 (1996) 511-523
    • (1996) J. Toxicol. Environ. Health , vol.49 , pp. 511-523
    • Miles, P.R.1    Bowman, L.2    Reasor, M.J.3
  • 23
    • 0034465935 scopus 로고    scopus 로고
    • Evidence of a no-effect level in silica-induced rat lung mutagenicity but not in fibrogenicity
    • Seiler F., Rehn B., Rehn S., and Bruch J. Evidence of a no-effect level in silica-induced rat lung mutagenicity but not in fibrogenicity. Arch. Toxicol. 74 (2001) 716-719
    • (2001) Arch. Toxicol. , vol.74 , pp. 716-719
    • Seiler, F.1    Rehn, B.2    Rehn, S.3    Bruch, J.4
  • 24
    • 33745714515 scopus 로고    scopus 로고
    • Interaction between primary alveolar macrophages and primary alveolar type II cells under basal conditions and after lipopolysaccharide or quartz exposure
    • Kanj R.S., Kang J.L., and Castranova V. Interaction between primary alveolar macrophages and primary alveolar type II cells under basal conditions and after lipopolysaccharide or quartz exposure. J. Toxicol. Environ. Health, A 69 (2006) 1097-1116
    • (2006) J. Toxicol. Environ. Health, A , vol.69 , pp. 1097-1116
    • Kanj, R.S.1    Kang, J.L.2    Castranova, V.3
  • 25
    • 0026133118 scopus 로고
    • Alveolar type II cells isolated after silica-induced lung injury in rats have increased surfactant protein A (SP-A) receptor activity
    • Suwabe A., Panos R.J., and Voelker D.R. Alveolar type II cells isolated after silica-induced lung injury in rats have increased surfactant protein A (SP-A) receptor activity. Am. J. Respir. Cell Mol. Biol. 4 (1991) 264-272
    • (1991) Am. J. Respir. Cell Mol. Biol. , vol.4 , pp. 264-272
    • Suwabe, A.1    Panos, R.J.2    Voelker, D.R.3
  • 26
    • 0028068497 scopus 로고
    • Effect of short-term exogenous pulmonary surfactant treatment on acute lung damage associated with the intratracheal instillation of silica
    • Antonini J.M., and Reasor M.J. Effect of short-term exogenous pulmonary surfactant treatment on acute lung damage associated with the intratracheal instillation of silica. J. Toxicol. Environ. Health 43 (1994) 85-101
    • (1994) J. Toxicol. Environ. Health , vol.43 , pp. 85-101
    • Antonini, J.M.1    Reasor, M.J.2
  • 27
    • 0028332911 scopus 로고
    • Acute silica toxicity: attenuation by amiodarone-induced pulmonary phospholipidosis
    • Antonini J.M., McCloud C.M., and Reasor M.J. Acute silica toxicity: attenuation by amiodarone-induced pulmonary phospholipidosis. Environ. Health Perspect. 102 (1994) 372-378
    • (1994) Environ. Health Perspect. , vol.102 , pp. 372-378
    • Antonini, J.M.1    McCloud, C.M.2    Reasor, M.J.3
  • 28
    • 0027754080 scopus 로고
    • Loss of cathepsin B activity in alveolar macrophages after in vitro quartz phagocytosis
    • Patzold S., Schmidt A., and Seidel A. Loss of cathepsin B activity in alveolar macrophages after in vitro quartz phagocytosis. J. Toxicol. Environ Health. 40 (1993) 547-554
    • (1993) J. Toxicol. Environ Health. , vol.40 , pp. 547-554
    • Patzold, S.1    Schmidt, A.2    Seidel, A.3
  • 29
    • 0026784806 scopus 로고
    • Influence of surfactant components and exposure geometry on the effects of quartz and asbestos on alveolar macrophages
    • Schimmelpfeng J., Drosselmeyer E., Hofheinz V., and Seidel A. Influence of surfactant components and exposure geometry on the effects of quartz and asbestos on alveolar macrophages. Environ. Health Perspect. 97 (1992) 225-231
    • (1992) Environ. Health Perspect. , vol.97 , pp. 225-231
    • Schimmelpfeng, J.1    Drosselmeyer, E.2    Hofheinz, V.3    Seidel, A.4
  • 30
    • 0026455189 scopus 로고
    • Contrasting respirable quartz and kaolin retention of lecithin surfactant and expression of membranolytic activity following phospholipase A2 digestion
    • Wallace W.E., Keane M.J., Mike P.S., Hill C.A., Vallyathan V., and Regad E.D. Contrasting respirable quartz and kaolin retention of lecithin surfactant and expression of membranolytic activity following phospholipase A2 digestion. J. Toxicol. Environ. Health 37 (1992) 391-409
    • (1992) J. Toxicol. Environ. Health , vol.37 , pp. 391-409
    • Wallace, W.E.1    Keane, M.J.2    Mike, P.S.3    Hill, C.A.4    Vallyathan, V.5    Regad, E.D.6
  • 31
    • 0034625550 scopus 로고    scopus 로고
    • Effects of simulated pulmonary surfactant on the cytotoxicity and DNA-damaging activity of respirable quartz and kaolin
    • Gao N., Keane M.J., Ong T., and Wallace W.E. Effects of simulated pulmonary surfactant on the cytotoxicity and DNA-damaging activity of respirable quartz and kaolin. J. Toxicol. Environ. Health, A 60 (2000) 153-167
    • (2000) J. Toxicol. Environ. Health, A , vol.60 , pp. 153-167
    • Gao, N.1    Keane, M.J.2    Ong, T.3    Wallace, W.E.4
  • 32
    • 0035883840 scopus 로고    scopus 로고
    • Effects of phospholipid surfactant on apoptosis induction by respirable quartz and kaolin in NR8383 rat pulmonary macrophages
    • Gao N., Keane M.J., Ong T., Ye J., Miller W.E., and Wallace W.E. Effects of phospholipid surfactant on apoptosis induction by respirable quartz and kaolin in NR8383 rat pulmonary macrophages. Toxicol. Appl. Pharmacol. 175 (2001) 217-225
    • (2001) Toxicol. Appl. Pharmacol. , vol.175 , pp. 217-225
    • Gao, N.1    Keane, M.J.2    Ong, T.3    Ye, J.4    Miller, W.E.5    Wallace, W.E.6
  • 33
    • 0031658821 scopus 로고    scopus 로고
    • Phospholipid surfactant adsorption by respirable quartz and in vitro expression of cytotoxicity and DNA damage
    • Liu X., Keane M.J., Harrison J.C., Cilento E.V., Ong T., and Wallace W.E. Phospholipid surfactant adsorption by respirable quartz and in vitro expression of cytotoxicity and DNA damage. Toxicol. Lett. 96-97 (1998) 77-84
    • (1998) Toxicol. Lett. , vol.96-97 , pp. 77-84
    • Liu, X.1    Keane, M.J.2    Harrison, J.C.3    Cilento, E.V.4    Ong, T.5    Wallace, W.E.6
  • 34
    • 0026322827 scopus 로고
    • Alveolar proteinosis and phospholipidoses of the lungs
    • Hook G.E. Alveolar proteinosis and phospholipidoses of the lungs. Toxicol. Pathol. 19 (1991) 482-513
    • (1991) Toxicol. Pathol. , vol.19 , pp. 482-513
    • Hook, G.E.1
  • 35
    • 0035523086 scopus 로고    scopus 로고
    • Receptors for unopsonized particles: the role of alveolar macrophage scavenger receptors
    • Palecanda A., and Kobzik L. Receptors for unopsonized particles: the role of alveolar macrophage scavenger receptors. Curr. Mol. Med. 1 (2001) 589-595
    • (2001) Curr. Mol. Med. , vol.1 , pp. 589-595
    • Palecanda, A.1    Kobzik, L.2
  • 36
    • 0029053842 scopus 로고
    • Lung macrophage uptake of unopsonized environmental particulates: role of scavenger-type receptors
    • Kobzik L. Lung macrophage uptake of unopsonized environmental particulates: role of scavenger-type receptors. J. Immunol. 155 (1995) 367-376
    • (1995) J. Immunol. , vol.155 , pp. 367-376
    • Kobzik, L.1
  • 37
    • 0034122925 scopus 로고    scopus 로고
    • The role of scavenger receptors in the innate immune system
    • Gough P.J., and Gordon S. The role of scavenger receptors in the innate immune system. Microbes Infect. 2 (2000) 305-311
    • (2000) Microbes Infect. , vol.2 , pp. 305-311
    • Gough, P.J.1    Gordon, S.2
  • 38
    • 0035092052 scopus 로고    scopus 로고
    • The function of scavenger receptors expressed by macrophages and their role in the regulation of inflammation
    • Peiser L., and Gordon S. The function of scavenger receptors expressed by macrophages and their role in the regulation of inflammation. Microbes Infect. 3 (2001) 149-159
    • (2001) Microbes Infect. , vol.3 , pp. 149-159
    • Peiser, L.1    Gordon, S.2
  • 40
    • 21744443099 scopus 로고    scopus 로고
    • The structure and function of MARCO, a macrophage class A scavenger receptor
    • (online publication)
    • Arredouani M.S., and Kobzik L. The structure and function of MARCO, a macrophage class A scavenger receptor. Cell. Mol. Biol. (Noisy-le-grand) 50 (2004) OL657-OL665 (online publication)
    • (2004) Cell. Mol. Biol. (Noisy-le-grand) , vol.50
    • Arredouani, M.S.1    Kobzik, L.2
  • 42
    • 0035846448 scopus 로고    scopus 로고
    • Molecular cloning of a mouse scavenger receptor with C-type lectin (SRCL). 1. A novel member of the scavenger receptor family
    • Nakamura K., Funakoshi H., Tokunaga F., and Nakamura T. Molecular cloning of a mouse scavenger receptor with C-type lectin (SRCL). 1. A novel member of the scavenger receptor family. Biochim. Biophys. Acta 1522 (2001) 53-58
    • (2001) Biochim. Biophys. Acta , vol.1522 , pp. 53-58
    • Nakamura, K.1    Funakoshi, H.2    Tokunaga, F.3    Nakamura, T.4
  • 43
    • 33744950384 scopus 로고    scopus 로고
    • Identification and characterization of murine SCARA5, a novel class A scavenger receptor that is expressed by populations of epithelial cells
    • Jiang Y., Oliver P., Davies K.E., and Platt N. Identification and characterization of murine SCARA5, a novel class A scavenger receptor that is expressed by populations of epithelial cells. J. Biol. Chem. 281 (2006) 11834-11845
    • (2006) J. Biol. Chem. , vol.281 , pp. 11834-11845
    • Jiang, Y.1    Oliver, P.2    Davies, K.E.3    Platt, N.4
  • 44
    • 0034800455 scopus 로고    scopus 로고
    • Is the class A macrophage scavenger receptor (SR-A) multifunctional? The mouse's tale
    • Platt N., and Gordon S. Is the class A macrophage scavenger receptor (SR-A) multifunctional? The mouse's tale. J. Clin. Invest. 108 (2001) 649-654
    • (2001) J. Clin. Invest. , vol.108 , pp. 649-654
    • Platt, N.1    Gordon, S.2
  • 45
    • 0034650457 scopus 로고    scopus 로고
    • Class A type II scavenger receptor mediates silica-induced apoptosis in Chinese hamster ovary cell line
    • Hamilton R.F., de Villiers W.J., and Holian A. Class A type II scavenger receptor mediates silica-induced apoptosis in Chinese hamster ovary cell line. Toxicol. Appl. Pharmacol. 162 (2000) 100-106
    • (2000) Toxicol. Appl. Pharmacol. , vol.162 , pp. 100-106
    • Hamilton, R.F.1    de Villiers, W.J.2    Holian, A.3
  • 46
    • 0027405555 scopus 로고
    • The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands
    • Acton S., Resnick D., Freeman M., Ekkel Y., Ashkenas J., and Krieger M. The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands. J. Biol. Chem. 268 (1993) 3530-3537
    • (1993) J. Biol. Chem. , vol.268 , pp. 3530-3537
    • Acton, S.1    Resnick, D.2    Freeman, M.3    Ekkel, Y.4    Ashkenas, J.5    Krieger, M.6
  • 47
    • 0032584585 scopus 로고    scopus 로고
    • Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain
    • Andersson L., and Freeman M.W. Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain. J. Biol. Chem. 273 (1998) 19592-19601
    • (1998) J. Biol. Chem. , vol.273 , pp. 19592-19601
    • Andersson, L.1    Freeman, M.W.2
  • 48
    • 0035395717 scopus 로고    scopus 로고
    • Cell surface regulation of silica-induced apoptosis by the SR-A scavenger receptor in a murine lung macrophage cell line (MH-S)
    • Chao S.K., Hamilton R.F., Pfau J.C., and Holian A. Cell surface regulation of silica-induced apoptosis by the SR-A scavenger receptor in a murine lung macrophage cell line (MH-S). Toxicol. Appl. Pharmacol. 174 (2001) 10-16
    • (2001) Toxicol. Appl. Pharmacol. , vol.174 , pp. 10-16
    • Chao, S.K.1    Hamilton, R.F.2    Pfau, J.C.3    Holian, A.4
  • 49
    • 3242782480 scopus 로고    scopus 로고
    • The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles
    • Arredouani M., Yang Z., Ning Y., Qin G., Soininen R., Tryggvason K., and Kobzik L. The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles. J. Exp. Med. 200 (2004) 267-272
    • (2004) J. Exp. Med. , vol.200 , pp. 267-272
    • Arredouani, M.1    Yang, Z.2    Ning, Y.3    Qin, G.4    Soininen, R.5    Tryggvason, K.6    Kobzik, L.7
  • 52
    • 34447503407 scopus 로고    scopus 로고
    • Crystal structure of the cysteine-rich domain of scavenger receptor MARCO reveals the presence of a basic and an acidic cluster that both contribute to ligand recognition
    • Ojala J.R., Pikkarainen T., Tuuttila A., Sandalova T., and Tryggvason K. Crystal structure of the cysteine-rich domain of scavenger receptor MARCO reveals the presence of a basic and an acidic cluster that both contribute to ligand recognition. J. Biol. Chem. 282 (2007) 16654-16666
    • (2007) J. Biol. Chem. , vol.282 , pp. 16654-16666
    • Ojala, J.R.1    Pikkarainen, T.2    Tuuttila, A.3    Sandalova, T.4    Tryggvason, K.5
  • 53
    • 0030296848 scopus 로고    scopus 로고
    • Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages
    • Iyer R., Hamilton R.F., Li L., and Holian A. Silica-induced apoptosis mediated via scavenger receptor in human alveolar macrophages. Toxicol. Appl. Pharmacol. 141 (1996) 84-92
    • (1996) Toxicol. Appl. Pharmacol. , vol.141 , pp. 84-92
    • Iyer, R.1    Hamilton, R.F.2    Li, L.3    Holian, A.4
  • 54
    • 22444451189 scopus 로고    scopus 로고
    • Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure
    • Beamer C.A., and Holian A. Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure. Am. J. Physiol., Lung Cell. Mol. Physiol. 289 (2005) L186-L195
    • (2005) Am. J. Physiol., Lung Cell. Mol. Physiol. , vol.289
    • Beamer, C.A.1    Holian, A.2
  • 55
    • 33845945947 scopus 로고    scopus 로고
    • MARCO mediates silica uptake and toxicity in alveolar macrophages from C57BL/6 mice
    • Hamilton Jr. R.F., Thakur S.A., Mayfair J.K., and Holian A. MARCO mediates silica uptake and toxicity in alveolar macrophages from C57BL/6 mice. J. Biol. Chem. 281 (2006) 34218-34226
    • (2006) J. Biol. Chem. , vol.281 , pp. 34218-34226
    • Hamilton Jr., R.F.1    Thakur, S.A.2    Mayfair, J.K.3    Holian, A.4
  • 57
    • 0031964445 scopus 로고    scopus 로고
    • Ligand binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathway
    • Hsu H.Y., Hajjar D.P., Khan K.M., and Falcone D.J. Ligand binding to macrophage scavenger receptor-A induces urokinase-type plasminogen activator expression by a protein kinase-dependent signaling pathway. J. Biol. Chem. 273 (1998) 1240-1246
    • (1998) J. Biol. Chem. , vol.273 , pp. 1240-1246
    • Hsu, H.Y.1    Hajjar, D.P.2    Khan, K.M.3    Falcone, D.J.4
  • 59
    • 0033579528 scopus 로고    scopus 로고
    • The processing of ligands by the class A scavenger receptor is dependent on signal information located in the cytoplasmic domain
    • Fong L.G., and Le D. The processing of ligands by the class A scavenger receptor is dependent on signal information located in the cytoplasmic domain. J. Biol. Chem. 274 (1999) 36808-36816
    • (1999) J. Biol. Chem. , vol.274 , pp. 36808-36816
    • Fong, L.G.1    Le, D.2
  • 60
    • 0035800775 scopus 로고    scopus 로고
    • Ligands of macrophage scavenger receptor induce cytokine expression via differential modulation of protein kinase signaling pathways
    • Hsu H.Y., Chiu S.L., Wen M.H., Chen K.Y., and Hua K.F. Ligands of macrophage scavenger receptor induce cytokine expression via differential modulation of protein kinase signaling pathways. J. Biol. Chem. 276 (2001) 28719-28730
    • (2001) J. Biol. Chem. , vol.276 , pp. 28719-28730
    • Hsu, H.Y.1    Chiu, S.L.2    Wen, M.H.3    Chen, K.Y.4    Hua, K.F.5
  • 61
    • 29144533040 scopus 로고    scopus 로고
    • Disparate regulation and function of the class A scavenger receptors SR-AI/II and MARCO
    • Jozefowski S., Arredouani M., Sulahian T., and Kobzik L. Disparate regulation and function of the class A scavenger receptors SR-AI/II and MARCO. J. Immunol. 175 (2005) 8032-8041
    • (2005) J. Immunol. , vol.175 , pp. 8032-8041
    • Jozefowski, S.1    Arredouani, M.2    Sulahian, T.3    Kobzik, L.4
  • 62
    • 7644232351 scopus 로고    scopus 로고
    • 2 production and suppression of IL-12 release in murine macrophages
    • 2 production and suppression of IL-12 release in murine macrophages. J. Leukoc. Biol. 76 (2004) 1066-1074
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 1066-1074
    • Jozefowski, S.1    Kobzik, L.2
  • 63
    • 0037184995 scopus 로고    scopus 로고
    • Pattern recognition receptors: doubling up for the innate immune response
    • Gordon S. Pattern recognition receptors: doubling up for the innate immune response. Cell 111 (2002) 927-930
    • (2002) Cell , vol.111 , pp. 927-930
    • Gordon, S.1
  • 64
    • 4344659759 scopus 로고    scopus 로고
    • Activation of murine macrophages by Neisseria meningitidis and IFN-γ in vitro: distinct roles of class A scavenger and Toll-like pattern recognition receptors in selective modulation of surface phenotype
    • Mukhopadhyay S., Peiser L., and Gordon S. Activation of murine macrophages by Neisseria meningitidis and IFN-γ in vitro: distinct roles of class A scavenger and Toll-like pattern recognition receptors in selective modulation of surface phenotype. J. Leukoc. Biol. 76 (2004) 577-584
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 577-584
    • Mukhopadhyay, S.1    Peiser, L.2    Gordon, S.3
  • 65
    • 0034822983 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms regulating silica-induced adhesion molecule expression in mice
    • Hubbard A.K., Thibodeau M., and Giardina C. Cellular and molecular mechanisms regulating silica-induced adhesion molecule expression in mice. J. Environ. Pathol. Toxicol. Oncol. 20 Suppl. 1 (2001) 45-51
    • (2001) J. Environ. Pathol. Toxicol. Oncol. , vol.20 , Issue.SUPPL. 1 , pp. 45-51
    • Hubbard, A.K.1    Thibodeau, M.2    Giardina, C.3
  • 66
    • 0038359740 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
    • Fubini B., and Hubbard A. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic. Biol. Med. 34 (2003) 1507-1516
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 1507-1516
    • Fubini, B.1    Hubbard, A.2
  • 67
    • 0028557249 scopus 로고
    • Generation of oxygen radicals and mechanisms of injury prevention
    • Castranova V. Generation of oxygen radicals and mechanisms of injury prevention. Environ. Health Perspect. 102 Suppl. 10 (1994) 65-68
    • (1994) Environ. Health Perspect. , vol.102 , Issue.SUPPL. 10 , pp. 65-68
    • Castranova, V.1
  • 69
    • 0347993913 scopus 로고    scopus 로고
    • Nitric oxide and superoxide in inflammation and immune regulation
    • Guzik T.J., Korbut R., and Adamek-Guzik T. Nitric oxide and superoxide in inflammation and immune regulation. J. Physiol. Pharmacol. 54 (2003) 469-487
    • (2003) J. Physiol. Pharmacol. , vol.54 , pp. 469-487
    • Guzik, T.J.1    Korbut, R.2    Adamek-Guzik, T.3
  • 70
    • 0023776077 scopus 로고
    • ESR evidence for the hydroxyl radical formation in aqueous suspension of quartz particles and its possible significance to lipid peroxidation in silicosis
    • Shi X.L., Dalal N.S., and Vallyathan V. ESR evidence for the hydroxyl radical formation in aqueous suspension of quartz particles and its possible significance to lipid peroxidation in silicosis. J. Toxicol. Environ. Health 25 (1988) 237-245
    • (1988) J. Toxicol. Environ. Health , vol.25 , pp. 237-245
    • Shi, X.L.1    Dalal, N.S.2    Vallyathan, V.3
  • 71
    • 0023796649 scopus 로고
    • Generation of free radicals from freshly fractured silica dust: potential role in acute silica-induced lung injury
    • Vallyathan V., Shi X.L., Dalal N.S., Irr W., and Castranova V. Generation of free radicals from freshly fractured silica dust: potential role in acute silica-induced lung injury. Am. Rev. Respir. Dis. 138 (1988) 1213-1219
    • (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 1213-1219
    • Vallyathan, V.1    Shi, X.L.2    Dalal, N.S.3    Irr, W.4    Castranova, V.5
  • 72
    • 0025740943 scopus 로고
    • Response of alveolar macrophages to in vitro exposure to freshly fractured versus aged silica dust: the ability of Prosil 28, an organosilane material, to coat silica and reduce its biological reactivity
    • Vallyathan V., Kang J.H., Van Dyke K., Dalal N.S., and Castranova V. Response of alveolar macrophages to in vitro exposure to freshly fractured versus aged silica dust: the ability of Prosil 28, an organosilane material, to coat silica and reduce its biological reactivity. J. Toxicol. Environ. Health 33 (1991) 303-315
    • (1991) J. Toxicol. Environ. Health , vol.33 , pp. 303-315
    • Vallyathan, V.1    Kang, J.H.2    Van Dyke, K.3    Dalal, N.S.4    Castranova, V.5
  • 74
    • 0015103260 scopus 로고
    • Influence of mode of disintegration on the fibrogenetic power of quartz particles
    • Gothe C.J., Lidstrom L., and Swensson A. Influence of mode of disintegration on the fibrogenetic power of quartz particles. Med. Lav. 62 (1971) 375-377
    • (1971) Med. Lav. , vol.62 , pp. 375-377
    • Gothe, C.J.1    Lidstrom, L.2    Swensson, A.3
  • 75
    • 0025645656 scopus 로고
    • Chemical functionalities at the silica surface determining its reactivity when inhaled: formation and reactivity of surface radicals
    • Fubini B., Giamello E., Volante M., and Bolis V. Chemical functionalities at the silica surface determining its reactivity when inhaled: formation and reactivity of surface radicals. Toxicol. Ind. Health 6 (1990) 571-598
    • (1990) Toxicol. Ind. Health , vol.6 , pp. 571-598
    • Fubini, B.1    Giamello, E.2    Volante, M.3    Bolis, V.4
  • 76
    • 0000699566 scopus 로고
    • The surface chemistry of crushed quartz dusts in relation to its pathogenicity
    • Fubini B., Bolis V., and Giamello E. The surface chemistry of crushed quartz dusts in relation to its pathogenicity. Inorg. Chim. Acta Bioinorg. Chem. 138 (1987) 193-197
    • (1987) Inorg. Chim. Acta Bioinorg. Chem. , vol.138 , pp. 193-197
    • Fubini, B.1    Bolis, V.2    Giamello, E.3
  • 79
    • 0034836268 scopus 로고    scopus 로고
    • Variability of biological responses to silicas: effect of origin, crystallinity, and state of surface on generation of reactive oxygen species and morphological transformation of mammalian cells
    • Fubini B., Fenoglio I., Elias Z., and Poirot O. Variability of biological responses to silicas: effect of origin, crystallinity, and state of surface on generation of reactive oxygen species and morphological transformation of mammalian cells. J. Environ. Pathol. Toxicol. Oncol. 20 Suppl. 1 (2001) 95-108
    • (2001) J. Environ. Pathol. Toxicol. Oncol. , vol.20 , Issue.SUPPL. 1 , pp. 95-108
    • Fubini, B.1    Fenoglio, I.2    Elias, Z.3    Poirot, O.4
  • 80
    • 0034051205 scopus 로고    scopus 로고
    • Pure-silica zeolites (Porosils) as model solids for the evaluation of the physicochemical features determining silica toxicity to macrophages
    • Fenoglio I., Croce A., Di Renzo F., Tiozzo R., and Fubini B. Pure-silica zeolites (Porosils) as model solids for the evaluation of the physicochemical features determining silica toxicity to macrophages. Chem. Res. Toxicol. 13 (2000) 489-500
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 489-500
    • Fenoglio, I.1    Croce, A.2    Di Renzo, F.3    Tiozzo, R.4    Fubini, B.5
  • 81
    • 0029616261 scopus 로고
    • Detection of surface free radical activity of respirable industrial fibres using supercoiled phi X174 RF1 plasmid DNA
    • Gilmour P.S., Beswick P.H., Brown D.M., and Donaldson K. Detection of surface free radical activity of respirable industrial fibres using supercoiled phi X174 RF1 plasmid DNA. Carcinogenesis 16 (1995) 2973-2979
    • (1995) Carcinogenesis , vol.16 , pp. 2973-2979
    • Gilmour, P.S.1    Beswick, P.H.2    Brown, D.M.3    Donaldson, K.4
  • 86
    • 0030887077 scopus 로고    scopus 로고
    • The role of oxygen free radicals in occupational and environmental lung diseases
    • Vallyathan V., and Shi X. The role of oxygen free radicals in occupational and environmental lung diseases. Environ. Health Perspect. 105 Suppl. 1 (1997) 165-177
    • (1997) Environ. Health Perspect. , vol.105 , Issue.SUPPL. 1 , pp. 165-177
    • Vallyathan, V.1    Shi, X.2
  • 87
    • 0026848618 scopus 로고
    • Enhanced generation of free radicals from phagocytes induced by mineral dusts
    • Vallyathan V., Mega J.F., Shi X., and Dalal N.S. Enhanced generation of free radicals from phagocytes induced by mineral dusts. Am. J. Respir. Cell Mol. Biol. 6 (1992) 404-413
    • (1992) Am. J. Respir. Cell Mol. Biol. , vol.6 , pp. 404-413
    • Vallyathan, V.1    Mega, J.F.2    Shi, X.3    Dalal, N.S.4
  • 88
    • 0028519724 scopus 로고
    • Intratracheal instillation of silica up-regulates inducible nitric oxide synthase gene expression and increases nitric oxide production in alveolar macrophages and neutrophils
    • Blackford Jr. J.A., Antonini J.M., Castranova V., and Dey R.D. Intratracheal instillation of silica up-regulates inducible nitric oxide synthase gene expression and increases nitric oxide production in alveolar macrophages and neutrophils. Am. J. Respir. Cell Mol. Biol. 11 (1994) 426-431
    • (1994) Am. J. Respir. Cell Mol. Biol. , vol.11 , pp. 426-431
    • Blackford Jr., J.A.1    Antonini, J.M.2    Castranova, V.3    Dey, R.D.4
  • 90
    • 0026783218 scopus 로고
    • Increased manganese superoxide dismutase protein in type II epithelial cells of rat lungs after inhalation of crocidolite asbestos or cristobalite silica
    • Holley J.A., Janssen Y.M., Mossman B.T., and Taatjes D.J. Increased manganese superoxide dismutase protein in type II epithelial cells of rat lungs after inhalation of crocidolite asbestos or cristobalite silica. Am. J. Pathol. 141 (1992) 475-485
    • (1992) Am. J. Pathol. , vol.141 , pp. 475-485
    • Holley, J.A.1    Janssen, Y.M.2    Mossman, B.T.3    Taatjes, D.J.4
  • 92
    • 0032713708 scopus 로고    scopus 로고
    • Critical role of GSH in silica-induced oxidative stress, cytotoxicity, and genotoxicity in alveolar macrophages
    • Zhang Z., Shen H.M., Zhang Q.F., and Ong C.N. Critical role of GSH in silica-induced oxidative stress, cytotoxicity, and genotoxicity in alveolar macrophages. Am. J. Physiol. 277 (1999) L743-L748
    • (1999) Am. J. Physiol. , vol.277
    • Zhang, Z.1    Shen, H.M.2    Zhang, Q.F.3    Ong, C.N.4
  • 93
    • 0033533580 scopus 로고    scopus 로고
    • Silica-induced generation of reactive oxygen species in Rat2 fibroblast: role in activation of mitogen-activated protein kinase
    • Cho Y.J., Seo M.S., Kim J.K., Lim Y., Chae G., Ha K.S., and Lee K.H. Silica-induced generation of reactive oxygen species in Rat2 fibroblast: role in activation of mitogen-activated protein kinase. Biochem. Biophys. Res. Commun. 262 (1999) 708-712
    • (1999) Biochem. Biophys. Res. Commun. , vol.262 , pp. 708-712
    • Cho, Y.J.1    Seo, M.S.2    Kim, J.K.3    Lim, Y.4    Chae, G.5    Ha, K.S.6    Lee, K.H.7
  • 94
    • 0028881118 scopus 로고
    • Dependence and reversal of nitric oxide production on NF-κB in silica and lipopolysaccharide-induced macrophages
    • Chen F., Kuhn D.C., Sun S.C., Gaydos L.J., and Demers L.M. Dependence and reversal of nitric oxide production on NF-κB in silica and lipopolysaccharide-induced macrophages. Biochem. Biophys. Res. Commun. 214 (1995) 839-846
    • (1995) Biochem. Biophys. Res. Commun. , vol.214 , pp. 839-846
    • Chen, F.1    Kuhn, D.C.2    Sun, S.C.3    Gaydos, L.J.4    Demers, L.M.5
  • 95
    • 0028972875 scopus 로고
    • Essential role of NF-κB activation in silica-induced inflammatory mediator production in macrophages
    • Chen F., Sun S.C., Kuh D.C., Gaydos L.J., and Demers L.M. Essential role of NF-κB activation in silica-induced inflammatory mediator production in macrophages. Biochem. Biophys. Res. Commun. 214 (1995) 985-992
    • (1995) Biochem. Biophys. Res. Commun. , vol.214 , pp. 985-992
    • Chen, F.1    Sun, S.C.2    Kuh, D.C.3    Gaydos, L.J.4    Demers, L.M.5
  • 98
    • 0032698065 scopus 로고    scopus 로고
    • Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK
    • Ding M., Shi X., Dong Z., Chen F., Lu Y., Castranova V., and Vallyathan V. Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK. J. Biol. Chem. 274 (1999) 30611-30616
    • (1999) J. Biol. Chem. , vol.274 , pp. 30611-30616
    • Ding, M.1    Shi, X.2    Dong, Z.3    Chen, F.4    Lu, Y.5    Castranova, V.6    Vallyathan, V.7
  • 99
    • 0035266157 scopus 로고    scopus 로고
    • 2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress
    • 2-terminal amino kinases, protracted expression of the activator protein-1 proto-oncogene, fra-1, and S-phase alterations are mediated via oxidative stress. Cancer Res 61 (2001) 1791-1795
    • (2001) Cancer Res , vol.61 , pp. 1791-1795
    • Shukla, A.1    Timblin, C.R.2    Hubbard, A.K.3    Bravman, J.4    Mossman, B.T.5
  • 100
    • 34247600505 scopus 로고    scopus 로고
    • Silica induces macrophage cytokines through phosphatidylcholine-specific phospholipase C with hydrogen peroxide
    • Liu H., Zhang H., and Forman H.J. Silica induces macrophage cytokines through phosphatidylcholine-specific phospholipase C with hydrogen peroxide. Am. J. Respir. Cell Mol. Biol. 36 (2007) 594-599
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.36 , pp. 594-599
    • Liu, H.1    Zhang, H.2    Forman, H.J.3
  • 101
    • 0030062331 scopus 로고    scopus 로고
    • Reactive oxygen intermediates as regulators of TNF-alpha production in rat lung inflammation induced by silica
    • Gossart S., Cambon C., Orfila C., Seguelas M.H., Lepert J.C., Rami J., Carre P., and Pipy B. Reactive oxygen intermediates as regulators of TNF-alpha production in rat lung inflammation induced by silica. J. Immunol. 156 (1996) 1540-1548
    • (1996) J. Immunol. , vol.156 , pp. 1540-1548
    • Gossart, S.1    Cambon, C.2    Orfila, C.3    Seguelas, M.H.4    Lepert, J.C.5    Rami, J.6    Carre, P.7    Pipy, B.8
  • 102
    • 0033032439 scopus 로고    scopus 로고
    • Silica-induced chemokine expression in alveolar type II cells is mediated by TNF-alpha-induced oxidant stress
    • Barrett E.G., Johnston C., Oberdorster G., and Finkelstein J.N. Silica-induced chemokine expression in alveolar type II cells is mediated by TNF-alpha-induced oxidant stress. Am. J. Physiol. 276 (1999) L979-L988
    • (1999) Am. J. Physiol. , vol.276
    • Barrett, E.G.1    Johnston, C.2    Oberdorster, G.3    Finkelstein, J.N.4
  • 103
    • 0033180489 scopus 로고    scopus 로고
    • Antioxidant treatment attenuates cytokine and chemokine levels in murine macrophages following silica exposure
    • Barrett E.G., Johnston C., Oberdorster G., and Finkelstein J.N. Antioxidant treatment attenuates cytokine and chemokine levels in murine macrophages following silica exposure. Toxicol. Appl. Pharmacol. 158 (1999) 211-220
    • (1999) Toxicol. Appl. Pharmacol. , vol.158 , pp. 211-220
    • Barrett, E.G.1    Johnston, C.2    Oberdorster, G.3    Finkelstein, J.N.4
  • 104
    • 0032508512 scopus 로고    scopus 로고
    • Environmental particulate-mediated cytokine production in lung epithelial cells (A549): role of preexisting inflammation and oxidant stress
    • Stringer B., and Kobzik L. Environmental particulate-mediated cytokine production in lung epithelial cells (A549): role of preexisting inflammation and oxidant stress. J. Toxicol. Environ. Health A 55 (1998) 31-44
    • (1998) J. Toxicol. Environ. Health A , vol.55 , pp. 31-44
    • Stringer, B.1    Kobzik, L.2
  • 105
    • 0242331711 scopus 로고    scopus 로고
    • Silica-induced caspase activation in mouse alveolar macrophages is dependent upon mitochondrial integrity and aspartic proteolysis
    • Thibodeau M., Giardina C., and Hubbard A.K. Silica-induced caspase activation in mouse alveolar macrophages is dependent upon mitochondrial integrity and aspartic proteolysis. Toxicol. Sci. 76 (2003) 91-101
    • (2003) Toxicol. Sci. , vol.76 , pp. 91-101
    • Thibodeau, M.1    Giardina, C.2    Hubbard, A.K.3
  • 106
    • 3242808193 scopus 로고    scopus 로고
    • Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity
    • Thibodeau M.S., Giardina C., Knecht D.A., Helble J., and Hubbard A.K. Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity. Toxicol. Sci. 80 (2004) 34-48
    • (2004) Toxicol. Sci. , vol.80 , pp. 34-48
    • Thibodeau, M.S.1    Giardina, C.2    Knecht, D.A.3    Helble, J.4    Hubbard, A.K.5
  • 107
    • 23644433533 scopus 로고    scopus 로고
    • Iron-dependent lysosomal destabilization initiates silica-induced apoptosis in murine macrophages
    • Persson H.L. Iron-dependent lysosomal destabilization initiates silica-induced apoptosis in murine macrophages. Toxicol. Lett. 159 (2005) 124-133
    • (2005) Toxicol. Lett. , vol.159 , pp. 124-133
    • Persson, H.L.1
  • 108
    • 0034823345 scopus 로고    scopus 로고
    • Silica and PM1648 modify human alveolar macrophage antigen-presenting cell activity in vitro
    • Hamilton Jr. R.F., Pfau J.C., Marshall G.D., and Holian A. Silica and PM1648 modify human alveolar macrophage antigen-presenting cell activity in vitro. J. Environ. Pathol. Toxicol. Oncol. 20 Suppl. 1 (2001) 75-84
    • (2001) J. Environ. Pathol. Toxicol. Oncol. , vol.20 , Issue.SUPPL. 1 , pp. 75-84
    • Hamilton Jr., R.F.1    Pfau, J.C.2    Marshall, G.D.3    Holian, A.4
  • 110
    • 36749057840 scopus 로고    scopus 로고
    • Antigen presenting cell population dynamics during murine silicosis
    • Beamer C.A., and Holian A. Antigen presenting cell population dynamics during murine silicosis. Am. J. Respir. Cell Mol. Biol. 37 (2007) 729-738
    • (2007) Am. J. Respir. Cell Mol. Biol. , vol.37 , pp. 729-738
    • Beamer, C.A.1    Holian, A.2
  • 113
    • 0031903142 scopus 로고    scopus 로고
    • Histopathological changes in enlarged thoracic lymph nodes during the development of silicosis in rats
    • Friedetzky A., Garn H., Kirchner A., and Gemsa D. Histopathological changes in enlarged thoracic lymph nodes during the development of silicosis in rats. Immunobiology 199 (1998) 119-132
    • (1998) Immunobiology , vol.199 , pp. 119-132
    • Friedetzky, A.1    Garn, H.2    Kirchner, A.3    Gemsa, D.4
  • 114
    • 0037340279 scopus 로고    scopus 로고
    • Silica accelerated systemic autoimmune disease in lupus-prone New Zealand mixed mice
    • Brown J.M., Archer A.J., Pfau J.C., and Holian A. Silica accelerated systemic autoimmune disease in lupus-prone New Zealand mixed mice. Clin. Exp. Immunol. 131 (2003) 415-421
    • (2003) Clin. Exp. Immunol. , vol.131 , pp. 415-421
    • Brown, J.M.1    Archer, A.J.2    Pfau, J.C.3    Holian, A.4
  • 115
    • 1642534473 scopus 로고    scopus 로고
    • Silica-exposed mice generate autoantibodies to apoptotic cells
    • Pfau J.C., Brown J.M., and Holian A. Silica-exposed mice generate autoantibodies to apoptotic cells. Toxicology 195 (2004) 167-176
    • (2004) Toxicology , vol.195 , pp. 167-176
    • Pfau, J.C.1    Brown, J.M.2    Holian, A.3
  • 117
    • 36048959334 scopus 로고    scopus 로고
    • Genetic polymorphisms in alveolar macrophage response-related genes, and risk of silicosis and pulmonary tuberculosis in Chinese iron miners
    • Qu Y., Tang Y., Cao D., Wu F., Liu J., Lu G., Zhang Z., and Xia Z. Genetic polymorphisms in alveolar macrophage response-related genes, and risk of silicosis and pulmonary tuberculosis in Chinese iron miners. Int. J. Hyg. Environ. Health 210 (2007) 679-689
    • (2007) Int. J. Hyg. Environ. Health , vol.210 , pp. 679-689
    • Qu, Y.1    Tang, Y.2    Cao, D.3    Wu, F.4    Liu, J.5    Lu, G.6    Zhang, Z.7    Xia, Z.8
  • 120
    • 34248340526 scopus 로고    scopus 로고
    • Silica, silicosis and tuberculosis
    • Rees D., and Murray J. Silica, silicosis and tuberculosis. Int. J. Tuberc. Lung Dis. 11 (2007) 474-484
    • (2007) Int. J. Tuberc. Lung Dis. , vol.11 , pp. 474-484
    • Rees, D.1    Murray, J.2


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