Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and -3 activation

Cell Death and Differentiation

Volumn 11, Issue 5, 2004, Pages 550-563

  Heinrich, M ^a   Neumeyer, J ^a   Jakob, M ^a   Hallas, C ^a   Tchikov, V ^a   Winoto Morbach, S ^a   Wickel, M ^a   Scheider Brachert, W ^b   Trauzold, A ^a   Hethke, A ^a   Schutze S ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

A SMase; Bid; Caspases; Cathepsin D.; Ceramide; TNF

Indexed keywords

CASPASE 3; CASPASE 9; CATHEPSIN D; CERAMIDE; PROTEIN BCL 2; PROTEIN BID; RAB PROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; CELL COMPARTMENTALIZATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TARGETING; PROTEIN TRANSPORT; REGULATORY MECHANISM; REVIEW; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CASPASE 3; CASPASE 9; CASPASES; CATHEPSIN D; CELLS, CULTURED; CERAMIDES; ENZYME ACTIVATION; FEMALE; FIBROBLASTS; HELA CELLS; HUMANS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 2442661614     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401382     Document Type: Review

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