cFLIPL prevents TRAIL-induced apoptosis of hepatocellular carcinoma cells by inhibiting the lysosomal pathway of apoptosis

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 292, Issue 5, 2007, Pages

  Guicciardi, Maria Eugenia ^a   Bronk, Steven F ^a   Werneburg, Nathan W ^a   Gores, Gregory J ^a  

^a MAYO CLINIC   (United States)

Author keywords

Caspase 8; Cathepsin B; p42 44 mitogen activated protein kinase; PD98059

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CATHEPSIN B; FLICE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEINASE; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CATHEPSIN; FLAVONOID; IMIDAZOLE DERIVATIVE; NITRILE; PYRIDINE DERIVATIVE; TNFSF10 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PERMEABILIZATION; CELL PROTECTION; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DRUG EXPOSURE; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LYSOSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; DRUG ANTAGONISM; DRUG EFFECT; LIVER TUMOR; METABOLISM; PATHOLOGY; PERMEABILITY; PHYSIOLOGY; PROTEIN TRANSPORT; TUMOR CELL LINE;

APOPTOSIS; BUTADIENES; CARCINOMA, HEPATOCELLULAR; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CATHEPSINS; CELL LINE, TUMOR; FLAVONOIDS; HUMANS; IMIDAZOLES; LIVER NEOPLASMS; LYSOSOMES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERMEABILITY; PROTEIN TRANSPORT; PYRIDINES; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 34347392130     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00497.2006     Document Type: Article

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