메뉴 건너뛰기




Volumn 9, Issue 4, 2008, Pages 219-236

The Cytokine Basis of Cachexia and its Treatment: Are They Ready for Prime Time?

Author keywords

anti cytokine medications; Cachexia; cytokines; pathophysiology

Indexed keywords

ACE 031; ACTIVIN RECEPTOR TYPE IIB AGONIST; ADALIMUMAB; AGENTS AFFECTING METABOLISM; ALPHA TOCOPHEROL; ARGININE; ASCORBIC ACID; ATLIZUMAB; CANNABINOID RECEPTOR AGONIST; CARNITINE; CREATINE; CYTOKINE; CYTOKINE ANTIBODY; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; ETANERCEPT; GAMMA INTERFERON; GLUTAMINE; INFLIXIMAB; INTERLEUKIN 6 ANTIBODY; MELANOCORTIN 4 RECEPTOR ANTAGONIST; METHOTREXATE; PENTOXIFYLLINE; PLACEBO; POLYUNSATURATED FATTY ACID; RETINOL; SCIO 469; SELECTIVE ANDROGEN RECEPTOR MODULATOR; THALIDOMIDE; UNINDEXED DRUG;

EID: 42649113078     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2008.01.003     Document Type: Review
Times cited : (55)

References (328)
  • 1
    • 0032849180 scopus 로고    scopus 로고
    • Body mass index and mortality among older people living in the community
    • F. Landi G. Zuccala G. Gambassi Body mass index and mortality among older people living in the community J Am Geriatr Soc 47 9 1999 1072 1076
    • (1999) J Am Geriatr Soc , vol.47 , Issue.9 , pp. 1072-1076
    • Landi, F.1    Zuccala, G.2    Gambassi, G.3
  • 2
    • 0023902171 scopus 로고
    • Malnutrition and wound healing
    • M.E. Young Malnutrition and wound healing Heart Lung 17 1 1988 60 67
    • (1988) Heart Lung , vol.17 , Issue.1 , pp. 60-67
    • Young, M.E.1
  • 3
    • 0023880294 scopus 로고
    • The link between nutritional status and clinical outcome: can nutritional intervention modify it?
    • D.T. Dempsey J.L. Mullen G.P. Buzby The link between nutritional status and clinical outcome: can nutritional intervention modify it? American Journal of Clinical Nutrition 47 Suppl 2 1988 352 356
    • (1988) American Journal of Clinical Nutrition , vol.47 , Issue.Suppl 2 , pp. 352-356
    • Dempsey, D.T.1    Mullen, J.L.2    Buzby, G.P.3
  • 4
    • 0035883480 scopus 로고    scopus 로고
    • Management of muscle wasting in cancer-associated cachexia: understanding gained from experimental studies
    • V.E. Baracos Management of muscle wasting in cancer-associated cachexia: understanding gained from experimental studies Cancer 92 6 Suppl 2001 1669 1677
    • (2001) Cancer , vol.92 , Issue.6 Suppl , pp. 1669-1677
    • Baracos, V.E.1
  • 5
    • 33646674302 scopus 로고    scopus 로고
    • Cachexia: pathophysiology and clinical relevance
    • J.E. Morley D.R. Thomas M.M. Wilson Cachexia: pathophysiology and clinical relevance Am J Clin Nutr 83 4 2006 735 743
    • (2006) Am J Clin Nutr , vol.83 , Issue.4 , pp. 735-743
    • Morley, J.E.1    Thomas, D.R.2    Wilson, M.M.3
  • 6
    • 0036828492 scopus 로고    scopus 로고
    • Distinguishing starvation from cachexia
    • D.R. Thomas Distinguishing starvation from cachexia Clin Geriatr Med 18 4 2002 883 891
    • (2002) Clin Geriatr Med , vol.18 , Issue.4 , pp. 883-891
    • Thomas, D.R.1
  • 7
    • 0030849677 scopus 로고    scopus 로고
    • The association of plasma IL-6 levels with functional disability in community-dwelling elderly
    • H.J. Cohen C.F. Pieper T. Harris K.M. Rao M.S. Currie The association of plasma IL-6 levels with functional disability in community-dwelling elderly J Gerontol 52 4 1997 M201 M208
    • (1997) J Gerontol , vol.52 , Issue.4 , pp. M201-M208
    • Cohen, H.J.1    Pieper, C.F.2    Harris, T.3    Rao, K.M.4    Currie, M.S.5
  • 8
    • 0030688961 scopus 로고    scopus 로고
    • ABC of palliative care: Anorexia, cachexia, and nutrition
    • E. Bruera ABC of palliative care Anorexia, cachexia, and nutrition Bmj 315 7117 1997 1219 1222
    • (1997) Bmj , vol.315 , Issue.7117 , pp. 1219-1222
    • Bruera, E.1
  • 9
    • 0029958555 scopus 로고    scopus 로고
    • The clinical relevance of circulating tumor necrosis factor-alpha in acute decompensated chronic heart failure without cachexia
    • R.V. Milani M.R. Mehra S. Endres The clinical relevance of circulating tumor necrosis factor-alpha in acute decompensated chronic heart failure without cachexia Chest 110 4 1996 992 995
    • (1996) Chest , vol.110 , Issue.4 , pp. 992-995
    • Milani, R.V.1    Mehra, M.R.2    Endres, S.3
  • 10
    • 0031029360 scopus 로고    scopus 로고
    • The importance of cachexia in the syndrome of heart failure
    • R. Ferrari The importance of cachexia in the syndrome of heart failure Eur Heart J 18 2 1997 187 189
    • (1997) Eur Heart J , vol.18 , Issue.2 , pp. 187-189
    • Ferrari, R.1
  • 11
    • 0028237131 scopus 로고
    • Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation
    • R. Roubenoff R. Roubenoff J. Cannon Rheumatoid cachexia: cytokine-driven hypermetabolism accompanying reduced body cell mass in chronic inflammation J Clin Invest 93 1994 2379 2386
    • (1994) J Clin Invest , vol.93 , pp. 2379-2386
    • Roubenoff, R.1    Roubenoff, R.2    Cannon, J.3
  • 12
    • 0037102166 scopus 로고    scopus 로고
    • Apoptosis as a potential mechanism of muscle cachexia in chronic obstructive pulmonary disease
    • M.I. Lewis Apoptosis as a potential mechanism of muscle cachexia in chronic obstructive pulmonary disease Am J Respir Crit Care Med 166 4 2002 434 436
    • (2002) Am J Respir Crit Care Med , vol.166 , Issue.4 , pp. 434-436
    • Lewis, M.I.1
  • 13
    • 0028130092 scopus 로고
    • Mechanisms of decreased food intake during weight loss in adult Crohn's disease patients without obvious malabsorption
    • D. Rigaud L.A. Angel M. Cerf Mechanisms of decreased food intake during weight loss in adult Crohn's disease patients without obvious malabsorption Am J Clin Nutr 60 5 1994 775 781
    • (1994) Am J Clin Nutr , vol.60 , Issue.5 , pp. 775-781
    • Rigaud, D.1    Angel, L.A.2    Cerf, M.3
  • 14
    • 0037394280 scopus 로고    scopus 로고
    • Getting beyond cross-sectional studies of abnormal nutritional indexes in dialysis patients
    • W.E. Mitch Getting beyond cross-sectional studies of abnormal nutritional indexes in dialysis patients Am J Clin Nutr 77 4 2003 760 761
    • (2003) Am J Clin Nutr , vol.77 , Issue.4 , pp. 760-761
    • Mitch, W.E.1
  • 15
    • 0031911147 scopus 로고    scopus 로고
    • Robert H Herman Memorial Award in Clinical Nutrition Lecture, 1997: Mechanisms causing loss of lean body mass in kidney disease
    • W.E. Mitch Robert H Herman Memorial Award in Clinical Nutrition Lecture, 1997 Mechanisms causing loss of lean body mass in kidney disease Am J Clin Nutr 67 3 1998 359 366
    • (1998) Am J Clin Nutr , vol.67 , Issue.3 , pp. 359-366
    • Mitch, W.E.1
  • 16
    • 5444268665 scopus 로고    scopus 로고
    • Rheumatoid cachexia: metabolic abnormalities, mechanisms and interventions
    • L.C. Rall R. Roubenoff Rheumatoid cachexia: metabolic abnormalities, mechanisms and interventions Rheumatology (Oxford) 43 10 2004 1219 1223
    • (2004) Rheumatology (Oxford) , vol.43 , Issue.10 , pp. 1219-1223
    • Rall, L.C.1    Roubenoff, R.2
  • 17
    • 33750538236 scopus 로고    scopus 로고
    • Regulation of the T cell response
    • S. Romagnani Regulation of the T cell response Clin Exp Allergy 36 11 2006 1357 1366
    • (2006) Clin Exp Allergy , vol.36 , Issue.11 , pp. 1357-1366
    • Romagnani, S.1
  • 18
    • 0842281425 scopus 로고    scopus 로고
    • Impact of nutritional status and nutrient supplements on immune responses and incidence of infection in older individuals
    • R.K. Chandra Impact of nutritional status and nutrient supplements on immune responses and incidence of infection in older individuals Ageing Res Rev 3 1 2004 91 104
    • (2004) Ageing Res Rev , vol.3 , Issue.1 , pp. 91-104
    • Chandra, R.K.1
  • 19
    • 0037927688 scopus 로고    scopus 로고
    • Catabolism of aging: is it an inflammatory process?
    • R. Roubenoff Catabolism of aging: is it an inflammatory process? Curr Opin Clin Nutr Metab Care 6 3 2003 295 299
    • (2003) Curr Opin Clin Nutr Metab Care , vol.6 , Issue.3 , pp. 295-299
    • Roubenoff, R.1
  • 20
    • 0022340621 scopus 로고
    • Parabiotic transfer of cancer anorexia/cachexia in male rats
    • J. Norton J. Moley M. Green R. Carson S. Morrison Parabiotic transfer of cancer anorexia/cachexia in male rats Cancer Res 45 1985 5547 5552
    • (1985) Cancer Res , vol.45 , pp. 5547-5552
    • Norton, J.1    Moley, J.2    Green, M.3    Carson, R.4    Morrison, S.5
  • 21
    • 0027693304 scopus 로고
    • Pathophysiology of cancer cachexia
    • U. Keller Pathophysiology of cancer cachexia Support Care Cancer 1 6 1993 290 294
    • (1993) Support Care Cancer , vol.1 , Issue.6 , pp. 290-294
    • Keller, U.1
  • 22
    • 0030868324 scopus 로고    scopus 로고
    • Cytokines and cachexia
    • P. Matthys A. Billiau Cytokines and cachexia Nutrition 13 9 1997 763 770
    • (1997) Nutrition , vol.13 , Issue.9 , pp. 763-770
    • Matthys, P.1    Billiau, A.2
  • 23
    • 0031892756 scopus 로고    scopus 로고
    • Cytokines and anorexia: a brief overview
    • C.R. Plata-Salaman Cytokines and anorexia: a brief overview Semin Oncol 25 1 Suppl 1 1998 64 72
    • (1998) Semin Oncol , vol.25 , Issue.1 Suppl 1 , pp. 64-72
    • Plata-Salaman, C.R.1
  • 24
    • 0032813012 scopus 로고    scopus 로고
    • Role of a proteolysis-inducing factor (PIF) in cachexia induced by a human melanoma (G361)
    • P.T. Todorov W.N. Field M.J. Tisdale Role of a proteolysis-inducing factor (PIF) in cachexia induced by a human melanoma (G361) Br J Cancer 80 11 1999 1734 1737
    • (1999) Br J Cancer , vol.80 , Issue.11 , pp. 1734-1737
    • Todorov, P.T.1    Field, W.N.2    Tisdale, M.J.3
  • 25
    • 37049031694 scopus 로고    scopus 로고
    • Identification and characterization of a membrane receptor for proteolysis-inducing factor on skeletal muscle
    • P.T. Todorov S.M. Wyke M.J. Tisdale Identification and characterization of a membrane receptor for proteolysis-inducing factor on skeletal muscle Cancer Res 67 23 2007 11419 11427
    • (2007) Cancer Res , vol.67 , Issue.23 , pp. 11419-11427
    • Todorov, P.T.1    Wyke, S.M.2    Tisdale, M.J.3
  • 26
    • 0032770726 scopus 로고    scopus 로고
    • Geriatric cachexia: the role of cytokines
    • S.S. Yeh M.W. Schuster Geriatric cachexia: the role of cytokines Am J Clin Nutr 70 2 1999 183 197
    • (1999) Am J Clin Nutr , vol.70 , Issue.2 , pp. 183-197
    • Yeh, S.S.1    Schuster, M.W.2
  • 27
    • 0029319901 scopus 로고
    • TNF, immunity and inflammatory disease: lessons of the past decade
    • B. Beutler TNF, immunity and inflammatory disease: lessons of the past decade J Investig Med 43 3 1995 227 235
    • (1995) J Investig Med , vol.43 , Issue.3 , pp. 227-235
    • Beutler, B.1
  • 28
    • 0025608770 scopus 로고
    • TNF in pathophysiology: biosynthetic regulation
    • B. Beutler TNF in pathophysiology: biosynthetic regulation J Invest Dermatol 95 6 Suppl 1990 81S 84S
    • (1990) J Invest Dermatol , vol.95 , Issue.6 Suppl , pp. 81S-84S
    • Beutler, B.1
  • 29
    • 0024405827 scopus 로고
    • The biology of cachectin/TNF–a primary mediator of the host response
    • B. Beutler A. Cerami The biology of cachectin/TNF–a primary mediator of the host response Annu Rev Immunol 7 1989 625 655
    • (1989) Annu Rev Immunol , vol.7 , pp. 625-655
    • Beutler, B.1    Cerami, A.2
  • 30
    • 1242329091 scopus 로고    scopus 로고
    • Leptin and TNF-alpha levels in patients with chronic obstructive pulmonary disease and their relationship to nutritional parameters
    • M. Calikoglu G. Sahin A. Unlu Leptin and TNF-alpha levels in patients with chronic obstructive pulmonary disease and their relationship to nutritional parameters Respiration 71 1 2004 45 50
    • (2004) Respiration , vol.71 , Issue.1 , pp. 45-50
    • Calikoglu, M.1    Sahin, G.2    Unlu, A.3
  • 31
    • 0035722694 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and muscle wasting: a cellular perspective
    • M.B. Reid Y.P. Li Tumor necrosis factor-alpha and muscle wasting: a cellular perspective Respir Res 2 5 2001 269 272
    • (2001) Respir Res , vol.2 , Issue.5 , pp. 269-272
    • Reid, M.B.1    Li, Y.P.2
  • 32
    • 0035259388 scopus 로고    scopus 로고
    • Loss of skeletal muscle in cancer: biochemical mechanisms
    • M.J. Tisdale Loss of skeletal muscle in cancer: biochemical mechanisms Front Biosci 6 2001 D164 D174
    • (2001) Front Biosci , vol.6 , pp. D164-D174
    • Tisdale, M.J.1
  • 33
    • 0036582784 scopus 로고    scopus 로고
    • Role of growth hormone, insulin-like growth factor-I, and insulin-like growth factor binding proteins in the catabolic response to injury and infection
    • C.H. Lang R.A. Frost Role of growth hormone, insulin-like growth factor-I, and insulin-like growth factor binding proteins in the catabolic response to injury and infection Curr Opin Clin Nutr Metab Care 5 3 2002 271 279
    • (2002) Curr Opin Clin Nutr Metab Care , vol.5 , Issue.3 , pp. 271-279
    • Lang, C.H.1    Frost, R.A.2
  • 34
    • 0034847075 scopus 로고    scopus 로고
    • Cytokines and oxidative signalling in skeletal muscle
    • M.B. Reid Y.P. Li Cytokines and oxidative signalling in skeletal muscle Acta Physiol Scand 171 3 2001 225 232
    • (2001) Acta Physiol Scand , vol.171 , Issue.3 , pp. 225-232
    • Reid, M.B.1    Li, Y.P.2
  • 35
    • 0037196562 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha exerts interleukin-6-dependent and -independent effects on cultured skeletal muscle cells
    • B. Alvarez L.S. Quinn S. Busquets M.T. Quiles F.J. Lopez-Soriano J.M. Argiles Tumor necrosis factor-alpha exerts interleukin-6-dependent and -independent effects on cultured skeletal muscle cells Biochim Biophys Acta 1542 1-3 2002 66 72
    • (2002) Biochim Biophys Acta , vol.1542 , Issue.1-3 , pp. 66-72
    • Alvarez, B.1    Quinn, L.S.2    Busquets, S.3    Quiles, M.T.4    Lopez-Soriano, F.J.5    Argiles, J.M.6
  • 38
    • 1642552162 scopus 로고    scopus 로고
    • Comparing outcome predictability of markers of malnutrition-inflammation complex syndrome in haemodialysis patients
    • K. Kalantar-Zadeh J.D. Kopple M.H. Humphreys G. Block Comparing outcome predictability of markers of malnutrition-inflammation complex syndrome in haemodialysis patients Nephrol Dial Transplant 19 6 2004 1507 1519
    • (2004) Nephrol Dial Transplant , vol.19 , Issue.6 , pp. 1507-1519
    • Kalantar-Zadeh, K.1    Kopple, J.D.2    Humphreys, M.H.3    Block, G.4
  • 39
    • 0034730251 scopus 로고    scopus 로고
    • NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia
    • D.C. Guttridge M.W. Mayo L.V. Madrid C.Y. Wang A.S. Baldwin Jr NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia Science 289 5488 2000 2363 2366
    • (2000) Science , vol.289 , Issue.5488 , pp. 2363-2366
    • Guttridge, D.C.1    Mayo, M.W.2    Madrid, L.V.3    Wang, C.Y.4    Baldwin, A.S.5
  • 40
    • 4043154377 scopus 로고    scopus 로고
    • Cancer cachexia is regulated by selective targeting of skeletal muscle gene products
    • S. Acharyya K.J. Ladner L.L. Nelsen Cancer cachexia is regulated by selective targeting of skeletal muscle gene products J Clin Invest 114 3 2004 370 378
    • (2004) J Clin Invest , vol.114 , Issue.3 , pp. 370-378
    • Acharyya, S.1    Ladner, K.J.2    Nelsen, L.L.3
  • 41
    • 0035020963 scopus 로고    scopus 로고
    • Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB
    • R.C. Langen A.M. Schols M.C. Kelders E.F. Wouters Y.M. Janssen-Heininger Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB Faseb J 15 7 2001 1169 1180
    • (2001) Faseb J , vol.15 , Issue.7 , pp. 1169-1180
    • Langen, R.C.1    Schols, A.M.2    Kelders, M.C.3    Wouters, E.F.4    Janssen-Heininger, Y.M.5
  • 42
    • 24344448272 scopus 로고    scopus 로고
    • Cancer cachexia results in an increase in TNF-alpha receptor gene expression in both skeletal muscle and adipose tissue
    • M. Figueras S. Busquets N. Carbo V. Almendro J.M. Argiles F.J. Lopez-Soriano Cancer cachexia results in an increase in TNF-alpha receptor gene expression in both skeletal muscle and adipose tissue Int J Oncol 27 3 2005 855 860
    • (2005) Int J Oncol , vol.27 , Issue.3 , pp. 855-860
    • Figueras, M.1    Busquets, S.2    Carbo, N.3    Almendro, V.4    Argiles, J.M.5    Lopez-Soriano, F.J.6
  • 44
    • 0031432550 scopus 로고    scopus 로고
    • IL-6-regulated transcription factors
    • S. Akira IL-6-regulated transcription factors Int J Biochem Cell Biol 29 12 1997 1401 1418
    • (1997) Int J Biochem Cell Biol , vol.29 , Issue.12 , pp. 1401-1418
    • Akira, S.1
  • 45
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • S. Akira T. Taga T. Kishimoto Interleukin-6 in biology and medicine Adv Immunol 54 1993 1 78
    • (1993) Adv Immunol , vol.54 , pp. 1-78
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 46
    • 0029893140 scopus 로고    scopus 로고
    • Role of interleukin-6 in macrophage function
    • S. Akira T. Kishimoto Role of interleukin-6 in macrophage function Curr Opin Hematol 3 1 1996 87 93
    • (1996) Curr Opin Hematol , vol.3 , Issue.1 , pp. 87-93
    • Akira, S.1    Kishimoto, T.2
  • 47
    • 34347261376 scopus 로고    scopus 로고
    • Central nervous system recognition of peripheral inflammation: a neural, hormonal collaboration
    • S.J. Hopkins Central nervous system recognition of peripheral inflammation: a neural, hormonal collaboration Acta Biomed 78 Suppl 1 2007 231 247
    • (2007) Acta Biomed , vol.78 , Issue.Suppl 1 , pp. 231-247
    • Hopkins, S.J.1
  • 48
    • 0142250392 scopus 로고    scopus 로고
    • Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence
    • M. Trikha R. Corringham B. Klein J.F. Rossi Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence Clin Cancer Res 9 13 2003 4653 4665
    • (2003) Clin Cancer Res , vol.9 , Issue.13 , pp. 4653-4665
    • Trikha, M.1    Corringham, R.2    Klein, B.3    Rossi, J.F.4
  • 49
    • 0032101969 scopus 로고    scopus 로고
    • Interleukin 6, but not ciliary neurotrophic factor or leukaemia inhibitory factor, is responsible for the acute phase response to turpentine-induced myositis
    • A. Kaibara N.J. Espat T. Auffenberg Interleukin 6, but not ciliary neurotrophic factor or leukaemia inhibitory factor, is responsible for the acute phase response to turpentine-induced myositis Cytokine 10 6 1998 452 456
    • (1998) Cytokine , vol.10 , Issue.6 , pp. 452-456
    • Kaibara, A.1    Espat, N.J.2    Auffenberg, T.3
  • 51
    • 10544222015 scopus 로고    scopus 로고
    • Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways
    • J. Fujita T. Tsujinaka M. Yano Anti-interleukin-6 receptor antibody prevents muscle atrophy in colon-26 adenocarcinoma-bearing mice with modulation of lysosomal and ATP-ubiquitin-dependent proteolytic pathways Int J Cancer 68 5 1996 637 643
    • (1996) Int J Cancer , vol.68 , Issue.5 , pp. 637-643
    • Fujita, J.1    Tsujinaka, T.2    Yano, M.3
  • 53
    • 13344261948 scopus 로고    scopus 로고
    • Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice
    • T. Tsujinaka J. Fujita C. Ebisui Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice J Clin Invest 97 1 1996 244 249
    • (1996) J Clin Invest , vol.97 , Issue.1 , pp. 244-249
    • Tsujinaka, T.1    Fujita, J.2    Ebisui, C.3
  • 54
    • 0033774034 scopus 로고    scopus 로고
    • Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma
    • T.P. Hong N.A. Andersen K. Nielsen Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma Eur Cytokine Netw 11 2 2000 193 205
    • (2000) Eur Cytokine Netw , vol.11 , Issue.2 , pp. 193-205
    • Hong, T.P.1    Andersen, N.A.2    Nielsen, K.3
  • 56
    • 0036398446 scopus 로고    scopus 로고
    • The IL-1 family and inflammatory diseases
    • C.A. Dinarello The IL-1 family and inflammatory diseases Clin Exp Rheumatol 20 5 Suppl 27 2002 S1 S13
    • (2002) Clin Exp Rheumatol , vol.20 , Issue.5 Suppl 27 , pp. S1-S13
    • Dinarello, C.A.1
  • 57
    • 0038687082 scopus 로고    scopus 로고
    • Interleukin-18 and host defense against infection
    • C.A. Dinarello G. Fantuzzi Interleukin-18 and host defense against infection J Infect Dis 187 Suppl 2 2003 S370 S384
    • (2003) J Infect Dis , vol.187 , Issue.Suppl 2 , pp. S370-S384
    • Dinarello, C.A.1    Fantuzzi, G.2
  • 58
    • 33744806876 scopus 로고    scopus 로고
    • Interleukin-1 mediates endothelin-1-induced fever and prostaglandin production in the preoptic area of rats
    • A.S. Fabricio G. Tringali G. Pozzoli Interleukin-1 mediates endothelin-1-induced fever and prostaglandin production in the preoptic area of rats Am J Physiol Regul Integr Comp Physiol 290 6 2006 R1515 R1523
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290 , Issue.6 , pp. R1515-R1523
    • Fabricio, A.S.1    Tringali, G.2    Pozzoli, G.3
  • 59
    • 33750484281 scopus 로고    scopus 로고
    • IL-1 resets glucose homeostasis at central levels
    • A. Del Rey E. Roggero A. Randolf IL-1 resets glucose homeostasis at central levels Proc Natl Acad Sci U S A 103 43 2006 16039 16044
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.43 , pp. 16039-16044
    • Del Rey, A.1    Roggero, E.2    Randolf, A.3
  • 60
    • 34848920411 scopus 로고    scopus 로고
    • Endothelial-specific knockdown of interleukin-1 (IL-1) type 1 receptor differentially alters CNS responses to IL-1 depending on its route of administration
    • S. Ching H. Zhang N. Belevych Endothelial-specific knockdown of interleukin-1 (IL-1) type 1 receptor differentially alters CNS responses to IL-1 depending on its route of administration J Neurosci 27 39 2007 10476 10486
    • (2007) J Neurosci , vol.27 , Issue.39 , pp. 10476-10486
    • Ching, S.1    Zhang, H.2    Belevych, N.3
  • 61
    • 0027165260 scopus 로고
    • Cachexia and the acute-phase protein response in inflammation are regulated by interleukin-6
    • H.S. Oldenburg M.A. Rogy D.D. Lazarus Cachexia and the acute-phase protein response in inflammation are regulated by interleukin-6 Eur J Immunol 23 8 1993 1889 1894
    • (1993) Eur J Immunol , vol.23 , Issue.8 , pp. 1889-1894
    • Oldenburg, H.S.1    Rogy, M.A.2    Lazarus, D.D.3
  • 62
    • 6944226294 scopus 로고    scopus 로고
    • Interleukin-1beta system in anorectic catabolic tumor-bearing rats
    • N.P. Turrin S.E. Ilyin D.A. Gayle Interleukin-1beta system in anorectic catabolic tumor-bearing rats Curr Opin Clin Nutr Metab Care 7 4 2004 419 426
    • (2004) Curr Opin Clin Nutr Metab Care , vol.7 , Issue.4 , pp. 419-426
    • Turrin, N.P.1    Ilyin, S.E.2    Gayle, D.A.3
  • 63
    • 0032806236 scopus 로고    scopus 로고
    • Systemic administration of lipopolysaccharide increases plasma leptin levels: blockade by soluble interleukin-1 receptor
    • J. Francis P.S. MohanKumar S.M. MohanKumar S.K. Quadri Systemic administration of lipopolysaccharide increases plasma leptin levels: blockade by soluble interleukin-1 receptor Endocrine 10 3 1999 291 295
    • (1999) Endocrine , vol.10 , Issue.3 , pp. 291-295
    • Francis, J.1    MohanKumar, P.S.2    MohanKumar, S.M.3    Quadri, S.K.4
  • 64
    • 0034985788 scopus 로고    scopus 로고
    • Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat
    • C.B. Lawrence N.J. Rothwell Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat J Neuroendocrinol 13 6 2001 490 495
    • (2001) J Neuroendocrinol , vol.13 , Issue.6 , pp. 490-495
    • Lawrence, C.B.1    Rothwell, N.J.2
  • 65
    • 34548089185 scopus 로고    scopus 로고
    • Regulation of central melanocortin signaling by interleukin-1 beta
    • J.M. Scarlett E.E. Jobst P.J. Enriori Regulation of central melanocortin signaling by interleukin-1 beta Endocrinology 148 9 2007 4217 4225
    • (2007) Endocrinology , vol.148 , Issue.9 , pp. 4217-4225
    • Scarlett, J.M.1    Jobst, E.E.2    Enriori, P.J.3
  • 66
    • 0032930281 scopus 로고    scopus 로고
    • Dual mechanisms of action of interferon-gamma in potentiating responses to LPS in mice: IL1, TNFalpha and IL6 production in serum and hypothermia
    • R. Blanque C. Meakin S. Millet C.R. Gardner Dual mechanisms of action of interferon-gamma in potentiating responses to LPS in mice: IL1, TNFalpha and IL6 production in serum and hypothermia Gen Pharmacol 32 4 1999 453 461
    • (1999) Gen Pharmacol , vol.32 , Issue.4 , pp. 453-461
    • Blanque, R.1    Meakin, C.2    Millet, S.3    Gardner, C.R.4
  • 67
    • 0019521733 scopus 로고
    • Follow-up observations on the effect of human leukocyte interferon in non-Hodgkin's lymphoma
    • A.C. Louie J.G. Gallagher K. Sikora R. Levy S.A. Rosenberg T.C. Merigan Follow-up observations on the effect of human leukocyte interferon in non-Hodgkin's lymphoma Blood 58 4 1981 712 718
    • (1981) Blood , vol.58 , Issue.4 , pp. 712-718
    • Louie, A.C.1    Gallagher, J.G.2    Sikora, K.3    Levy, R.4    Rosenberg, S.A.5    Merigan, T.C.6
  • 68
    • 0025887050 scopus 로고
    • Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells
    • P. Matthys R. Dijkmans P. Proost Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells Int J Cancer 49 1 1991 77 82
    • (1991) Int J Cancer , vol.49 , Issue.1 , pp. 77-82
    • Matthys, P.1    Dijkmans, R.2    Proost, P.3
  • 69
    • 0026032432 scopus 로고
    • Anti-interferon-gamma antibody treatment, growth of Lewis lung tumours in mice and tumour-associated cachexia
    • P. Matthys H. Heremans G. Opdenakker A. Billiau Anti-interferon-gamma antibody treatment, growth of Lewis lung tumours in mice and tumour-associated cachexia Eur J Cancer 27 2 1991 182 187
    • (1991) Eur J Cancer , vol.27 , Issue.2 , pp. 182-187
    • Matthys, P.1    Heremans, H.2    Opdenakker, G.3    Billiau, A.4
  • 70
    • 0032566814 scopus 로고    scopus 로고
    • Increased appetite augments hypothalamic NPY Y1 receptor gene expression: effects of anorexigenic ciliary neurotropic factor
    • B. Xu P.S. Kalra L.L. Moldawer S.P. Kalra Increased appetite augments hypothalamic NPY Y1 receptor gene expression: effects of anorexigenic ciliary neurotropic factor Regul Pept 75-76 1998 391 395
    • (1998) Regul Pept , vol.75-76 , pp. 391-395
    • Xu, B.1    Kalra, P.S.2    Moldawer, L.L.3    Kalra, S.P.4
  • 71
    • 0031788012 scopus 로고    scopus 로고
    • Anorectic effects of the cytokine, ciliary neurotropic factor, are mediated by hypothalamic neuropeptide Y: comparison with leptin
    • B. Xu M.G. Dube P.S. Kalra Anorectic effects of the cytokine, ciliary neurotropic factor, are mediated by hypothalamic neuropeptide Y: comparison with leptin Endocrinology 139 2 1998 466 473
    • (1998) Endocrinology , vol.139 , Issue.2 , pp. 466-473
    • Xu, B.1    Dube, M.G.2    Kalra, P.S.3
  • 72
    • 0031972988 scopus 로고    scopus 로고
    • Neuropeptide Y (NPY) Y1 receptor mRNA is upregulated in association with transient hyperphagia and body weight gain: evidence for a hypothalamic site for concurrent development of leptin resistance
    • P.S. Kalra M.G. Dube B. Xu W.G. Farmerie S.P. Kalra Neuropeptide Y (NPY) Y1 receptor mRNA is upregulated in association with transient hyperphagia and body weight gain: evidence for a hypothalamic site for concurrent development of leptin resistance J Neuroendocrinol 10 1 1998 43 49
    • (1998) J Neuroendocrinol , vol.10 , Issue.1 , pp. 43-49
    • Kalra, P.S.1    Dube, M.G.2    Xu, B.3    Farmerie, W.G.4    Kalra, S.P.5
  • 73
    • 0033840684 scopus 로고    scopus 로고
    • Neuropeptide Y counteracts the anorectic and weight reducing effects of ciliary neurotropic factor
    • S. Pu H. Dhillon L.L. Moldawer P.S. Kalra S.P. Kalra Neuropeptide Y counteracts the anorectic and weight reducing effects of ciliary neurotropic factor J Neuroendocrinol 12 9 2000 827 832
    • (2000) J Neuroendocrinol , vol.12 , Issue.9 , pp. 827-832
    • Pu, S.1    Dhillon, H.2    Moldawer, L.L.3    Kalra, P.S.4    Kalra, S.P.5
  • 74
    • 33746037555 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice
    • G.R. Steinberg M.J. Watt B.C. Fam Ciliary neurotrophic factor suppresses hypothalamic AMP-kinase signaling in leptin-resistant obese mice Endocrinology 147 8 2006 3906 3914
    • (2006) Endocrinology , vol.147 , Issue.8 , pp. 3906-3914
    • Steinberg, G.R.1    Watt, M.J.2    Fam, B.C.3
  • 75
    • 0028956741 scopus 로고
    • Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice
    • G. Fantuzzi F. Benigni M. Sironi Ciliary neurotrophic factor (CNTF) induces serum amyloid A, hypoglycaemia and anorexia, and potentiates IL-1 induced corticosterone and IL-6 production in mice Cytokine 7 2 1995 150 156
    • (1995) Cytokine , vol.7 , Issue.2 , pp. 150-156
    • Fantuzzi, G.1    Benigni, F.2    Sironi, M.3
  • 76
    • 33646570554 scopus 로고    scopus 로고
    • CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK
    • M.J. Watt N. Dzamko W.G. Thomas CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK Nat Med 12 5 2006 541 548
    • (2006) Nat Med , vol.12 , Issue.5 , pp. 541-548
    • Watt, M.J.1    Dzamko, N.2    Thomas, W.G.3
  • 77
    • 34447641485 scopus 로고    scopus 로고
    • The novel mechanism of recombinant human ciliary neurotrophic factor on the anti-diabetes activity
    • Q.S. Liu M. Gao S.Y. Zhu The novel mechanism of recombinant human ciliary neurotrophic factor on the anti-diabetes activity Basic Clin Pharmacol Toxicol 101 2 2007 78 84
    • (2007) Basic Clin Pharmacol Toxicol , vol.101 , Issue.2 , pp. 78-84
    • Liu, Q.S.1    Gao, M.2    Zhu, S.Y.3
  • 78
    • 33646576549 scopus 로고    scopus 로고
    • Overcoming insulin resistance with CNTF
    • R.S. Ahima Overcoming insulin resistance with CNTF Nat Med 12 5 2006 511 512
    • (2006) Nat Med , vol.12 , Issue.5 , pp. 511-512
    • Ahima, R.S.1
  • 79
    • 33645889377 scopus 로고    scopus 로고
    • Ciliary neural trophic factor: mimicking leptin's effects in skeletal muscle?
    • D.J. Dyck Ciliary neural trophic factor: mimicking leptin's effects in skeletal muscle? Endocrinology 147 5 2006 2075 2076
    • (2006) Endocrinology , vol.147 , Issue.5 , pp. 2075-2076
    • Dyck, D.J.1
  • 80
    • 0345060844 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice
    • M.W. Sleeman K. Garcia R. Liu Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice Proc Natl Acad Sci U S A 100 24 2003 14297 14302
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.24 , pp. 14297-14302
    • Sleeman, M.W.1    Garcia, K.2    Liu, R.3
  • 81
    • 0033987607 scopus 로고    scopus 로고
    • Effects of ciliary neurotrophic factor (CNTF) on protein turnover in cultured muscle cells
    • M.C. Wang N.E. Forsberg Effects of ciliary neurotrophic factor (CNTF) on protein turnover in cultured muscle cells Cytokine 12 1 2000 41 48
    • (2000) Cytokine , vol.12 , Issue.1 , pp. 41-48
    • Wang, M.C.1    Forsberg, N.E.2
  • 82
    • 4043115524 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor upregulates ubiquitin-proteasome components in a rat model of neuronal injury
    • D.H. Jho H.H. Engelhard R. Gandhi Ciliary neurotrophic factor upregulates ubiquitin-proteasome components in a rat model of neuronal injury Cytokine 27 6 2004 142 151
    • (2004) Cytokine , vol.27 , Issue.6 , pp. 142-151
    • Jho, D.H.1    Engelhard, H.H.2    Gandhi, R.3
  • 83
    • 0031985677 scopus 로고    scopus 로고
    • Effect of ciliary neurotrophic factor on body temperature and cerebrospinal fluid prostanoids in the cat
    • E.S. Akarsu I. Bishai F. Coceani Effect of ciliary neurotrophic factor on body temperature and cerebrospinal fluid prostanoids in the cat Brain Res Bull 45 1 1998 9 14
    • (1998) Brain Res Bull , vol.45 , Issue.1 , pp. 9-14
    • Akarsu, E.S.1    Bishai, I.2    Coceani, F.3
  • 85
    • 34250862302 scopus 로고    scopus 로고
    • Leptin analog antagonizes leptin effects on food intake and body weight but mimics leptin-induced vagal afferent activation
    • J.H. Peters S.M. Simasko R.C. Ritter Leptin analog antagonizes leptin effects on food intake and body weight but mimics leptin-induced vagal afferent activation Endocrinology 148 6 2007 2878 2885
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 2878-2885
    • Peters, J.H.1    Simasko, S.M.2    Ritter, R.C.3
  • 86
    • 33744467955 scopus 로고    scopus 로고
    • The hypothalamic control of feeding and thermogenesis: implications on the development of obesity
    • L.A. Velloso The hypothalamic control of feeding and thermogenesis: implications on the development of obesity [in Portuguese] Arq Bras Endocrinol Metabol 50 2 2006 165 176
    • (2006) Arq Bras Endocrinol Metabol , vol.50 , Issue.2 , pp. 165-176
    • Velloso, L.A.1
  • 87
    • 33947305970 scopus 로고    scopus 로고
    • Central interleukin-1 (IL1) signaling is required for pharmacological, but not physiological, effects of leptin on energy balance
    • B.E. Wisse K. Ogimoto G.J. Morton D.L. Williams M.W. Schwartz Central interleukin-1 (IL1) signaling is required for pharmacological, but not physiological, effects of leptin on energy balance Brain Res 1144 2007 101 106
    • (2007) Brain Res , vol.1144 , pp. 101-106
    • Wisse, B.E.1    Ogimoto, K.2    Morton, G.J.3    Williams, D.L.4    Schwartz, M.W.5
  • 88
    • 17344384196 scopus 로고    scopus 로고
    • Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia
    • P. Sarraf R.C. Frederich E.M. Turner Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexia J Exp Med 185 1 1997 171 175
    • (1997) J Exp Med , vol.185 , Issue.1 , pp. 171-175
    • Sarraf, P.1    Frederich, R.C.2    Turner, E.M.3
  • 89
    • 0032848779 scopus 로고    scopus 로고
    • Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin
    • Y. Ogawa H. Masuzaki K. Hosoda Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin Diabetes 48 9 1999 1822 1829
    • (1999) Diabetes , vol.48 , Issue.9 , pp. 1822-1829
    • Ogawa, Y.1    Masuzaki, H.2    Hosoda, K.3
  • 90
    • 33846446839 scopus 로고    scopus 로고
    • Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent
    • J. Zhang M.K. Matheny N. Tumer M.K. Mitchell P.J. Scarpace Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food after high-fat feeding are leptin dependent Am J Physiol Regul Integr Comp Physiol 292 2 2007 R868 R874
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , Issue.2 , pp. R868-R874
    • Zhang, J.1    Matheny, M.K.2    Tumer, N.3    Mitchell, M.K.4    Scarpace, P.J.5
  • 91
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans
    • M.W. Schwartz E. Peskind M. Raskind E.J. Boyko D. Porte Jr Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans Nat Med 2 5 1996 589 593
    • (1996) Nat Med , vol.2 , Issue.5 , pp. 589-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3    Boyko, E.J.4    Porte, D.5
  • 92
    • 0033306878 scopus 로고    scopus 로고
    • Leptin responses to overfeeding: relationship with body fat and nonexercise activity thermogenesis
    • J.A. Levine N.L. Eberhardt M.D. Jensen Leptin responses to overfeeding: relationship with body fat and nonexercise activity thermogenesis J Clin Endocrinol Metab 84 8 1999 2751 2754
    • (1999) J Clin Endocrinol Metab , vol.84 , Issue.8 , pp. 2751-2754
    • Levine, J.A.1    Eberhardt, N.L.2    Jensen, M.D.3
  • 93
    • 0032838228 scopus 로고    scopus 로고
    • Mechanisms regulating leptin production: implications for control of energy balance
    • P.J. Havel Mechanisms regulating leptin production: implications for control of energy balance Am J Clin Nutr 70 3 1999 305 306
    • (1999) Am J Clin Nutr , vol.70 , Issue.3 , pp. 305-306
    • Havel, P.J.1
  • 94
    • 33847654254 scopus 로고    scopus 로고
    • Leptin and C-reactive protein levels correlate during minor infection in children
    • R. Somech S. Reif A. Golander Z. Spirer Leptin and C-reactive protein levels correlate during minor infection in children Isr Med Assoc J 9 2 2007 76 78
    • (2007) Isr Med Assoc J , vol.9 , Issue.2 , pp. 76-78
    • Somech, R.1    Reif, S.2    Golander, A.3    Spirer, Z.4
  • 95
    • 23044436608 scopus 로고    scopus 로고
    • Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kappaB, peroxisomal proliferator-activated receptor-gamma and extracellularly regulated kinase 1/2
    • M. Lappas M. Permezel G.E. Rice Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kappaB, peroxisomal proliferator-activated receptor-gamma and extracellularly regulated kinase 1/2 Endocrinology 146 8 2005 3334 3342
    • (2005) Endocrinology , vol.146 , Issue.8 , pp. 3334-3342
    • Lappas, M.1    Permezel, M.2    Rice, G.E.3
  • 97
    • 0036313102 scopus 로고    scopus 로고
    • Novel role for prostaglandin E2 in fish hepatocytes: regulation of glucose metabolism
    • E.R. Busby G.A. Cooper T.P. Mommsen Novel role for prostaglandin E2 in fish hepatocytes: regulation of glucose metabolism J Endocrinol 174 1 2002 137 146
    • (2002) J Endocrinol , vol.174 , Issue.1 , pp. 137-146
    • Busby, E.R.1    Cooper, G.A.2    Mommsen, T.P.3
  • 98
    • 33846158824 scopus 로고    scopus 로고
    • IL-1beta and LPS induce anorexia by distinct mechanisms differentially dependent on microsomal prostaglandin E synthase-1
    • L. Elander L. Engstrom M. Hallbeck A. Blomqvist IL-1beta and LPS induce anorexia by distinct mechanisms differentially dependent on microsomal prostaglandin E synthase-1 Am J Physiol Regul Integr Comp Physiol 292 1 2007 R258 R267
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , Issue.1 , pp. R258-R267
    • Elander, L.1    Engstrom, L.2    Hallbeck, M.3    Blomqvist, A.4
  • 99
    • 0023789634 scopus 로고
    • Tumor necrosis factor-induced activation of peritoneal macrophages is regulated by prostaglandin E2 and cAMP
    • V. Lehmmann B. Benninghoff W. Droge Tumor necrosis factor-induced activation of peritoneal macrophages is regulated by prostaglandin E2 and cAMP J Immunol 141 2 1988 587 591
    • (1988) J Immunol , vol.141 , Issue.2 , pp. 587-591
    • Lehmmann, V.1    Benninghoff, B.2    Droge, W.3
  • 100
    • 0024390214 scopus 로고
    • Role of prostaglandins in tumour necrosis factor induced weight loss
    • S.M. Mahony M.J. Tisdale Role of prostaglandins in tumour necrosis factor induced weight loss Br J Cancer 60 1 1989 51 55
    • (1989) Br J Cancer , vol.60 , Issue.1 , pp. 51-55
    • Mahony, S.M.1    Tisdale, M.J.2
  • 101
    • 0027237389 scopus 로고
    • Mechanism of muscle protein degradation in cancer cachexia
    • K.L. Smith M.J. Tisdale Mechanism of muscle protein degradation in cancer cachexia Br J Cancer 68 2 1993 314 318
    • (1993) Br J Cancer , vol.68 , Issue.2 , pp. 314-318
    • Smith, K.L.1    Tisdale, M.J.2
  • 102
    • 0025303165 scopus 로고
    • Interleukin-6 production by endotoxin-stimulated Kupffer cells is regulated by prostaglandin E2
    • M.P. Callery M.J. Mangino T. Kamei M.W. Flye Interleukin-6 production by endotoxin-stimulated Kupffer cells is regulated by prostaglandin E2 J Surg Res 48 6 1990 523 527
    • (1990) J Surg Res , vol.48 , Issue.6 , pp. 523-527
    • Callery, M.P.1    Mangino, M.J.2    Kamei, T.3    Flye, M.W.4
  • 103
    • 0027945087 scopus 로고
    • Anti-inflammatory treatment may prolong survival in undernourished patients with metastatic solid tumors
    • K. Lundholm J. Gelin A. Hyltander Anti-inflammatory treatment may prolong survival in undernourished patients with metastatic solid tumors Cancer Res 54 21 1994 5602 5606
    • (1994) Cancer Res , vol.54 , Issue.21 , pp. 5602-5606
    • Lundholm, K.1    Gelin, J.2    Hyltander, A.3
  • 104
    • 0026083223 scopus 로고
    • Effects of indomethacin, cytokines, and cyclosporin A on tumor growth and the subsequent development of cancer cachexia
    • J. Gelin C. Andersson K. Lundholm Effects of indomethacin, cytokines, and cyclosporin A on tumor growth and the subsequent development of cancer cachexia Cancer Res 51 3 1991 880 885
    • (1991) Cancer Res , vol.51 , Issue.3 , pp. 880-885
    • Gelin, J.1    Andersson, C.2    Lundholm, K.3
  • 105
    • 1642570481 scopus 로고    scopus 로고
    • Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: microarray deoxyribonucleic acid-chip analysis of gene expression
    • V. Prima M. Tennant O.S. Gorbatyuk N. Muzyczka P.J. Scarpace S. Zolotukhin Differential modulation of energy balance by leptin, ciliary neurotrophic factor, and leukemia inhibitory factor gene delivery: microarray deoxyribonucleic acid-chip analysis of gene expression Endocrinology 145 4 2004 2035 2045
    • (2004) Endocrinology , vol.145 , Issue.4 , pp. 2035-2045
    • Prima, V.1    Tennant, M.2    Gorbatyuk, O.S.3    Muzyczka, N.4    Scarpace, P.J.5    Zolotukhin, S.6
  • 106
    • 33750364393 scopus 로고    scopus 로고
    • Altered neuronal responses and regulation of neurotrophic proteins in the medial septum following fimbria-fornix transection in CNTF- and leukaemia inhibitory factor-deficient mice
    • T. Naumann A. Steup O. Schnell Altered neuronal responses and regulation of neurotrophic proteins in the medial septum following fimbria-fornix transection in CNTF- and leukaemia inhibitory factor-deficient mice Eur J Neurosci 24 8 2006 2223 2232
    • (2006) Eur J Neurosci , vol.24 , Issue.8 , pp. 2223-2232
    • Naumann, T.1    Steup, A.2    Schnell, O.3
  • 107
    • 32944456073 scopus 로고    scopus 로고
    • Effects of cannabinoids on hypothalamic and reproductive function
    • M. Maccarrone T. Wenger Effects of cannabinoids on hypothalamic and reproductive function Handb Exp Pharmacol 168 2005 555 571
    • (2005) Handb Exp Pharmacol , vol.168 , pp. 555-571
    • Maccarrone, M.1    Wenger, T.2
  • 108
    • 0031656804 scopus 로고    scopus 로고
    • Mechanism of muscle protein degradation induced by a cancer cachectic factor
    • M.J. Lorite M.G. Thompson J.L. Drake G. Carling M.J. Tisdale Mechanism of muscle protein degradation induced by a cancer cachectic factor Br J Cancer 78 7 1998 850 856
    • (1998) Br J Cancer , vol.78 , Issue.7 , pp. 850-856
    • Lorite, M.J.1    Thompson, M.G.2    Drake, J.L.3    Carling, G.4    Tisdale, M.J.5
  • 109
    • 0037561931 scopus 로고    scopus 로고
    • The ‘cancer cachectic factor’
    • M.J. Tisdale The ‘cancer cachectic factor’ Support Care Cancer 11 2 2003 73 78
    • (2003) Support Care Cancer , vol.11 , Issue.2 , pp. 73-78
    • Tisdale, M.J.1
  • 110
    • 14944352786 scopus 로고    scopus 로고
    • NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle
    • S.M. Wyke M.J. Tisdale NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle Br J Cancer 92 4 2005 711 721
    • (2005) Br J Cancer , vol.92 , Issue.4 , pp. 711-721
    • Wyke, S.M.1    Tisdale, M.J.2
  • 111
    • 0034934948 scopus 로고    scopus 로고
    • Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF)
    • M.J. Lorite H.J. Smith J.A. Arnold A. Morris M.G. Thompson M.J. Tisdale Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF) Br J Cancer 85 2 2001 297 302
    • (2001) Br J Cancer , vol.85 , Issue.2 , pp. 297-302
    • Lorite, M.J.1    Smith, H.J.2    Arnold, J.A.3    Morris, A.4    Thompson, M.G.5    Tisdale, M.J.6
  • 112
    • 5444262078 scopus 로고    scopus 로고
    • IKKbeta/NF-kappaB activation causes severe muscle wasting in mice
    • D. Cai J.D. Frantz N.E. Tawa Jr. IKKbeta/NF-kappaB activation causes severe muscle wasting in mice Cell 119 2 2004 285 298
    • (2004) Cell , vol.119 , Issue.2 , pp. 285-298
    • Cai, D.1    Frantz, J.D.2    Tawa, N.E.3
  • 113
    • 0141887308 scopus 로고    scopus 로고
    • Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB
    • A.S. Whitehouse M.J. Tisdale Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB Br J Cancer 89 6 2003 1116 1122
    • (2003) Br J Cancer , vol.89 , Issue.6 , pp. 1116-1122
    • Whitehouse, A.S.1    Tisdale, M.J.2
  • 114
  • 115
    • 1942437502 scopus 로고    scopus 로고
    • Role of lipid-mobilising factor (LMF) in protecting tumour cells from oxidative damage
    • P.M. Sanders M.J. Tisdale Role of lipid-mobilising factor (LMF) in protecting tumour cells from oxidative damage Br J Cancer 90 6 2004 1274 1278
    • (2004) Br J Cancer , vol.90 , Issue.6 , pp. 1274-1278
    • Sanders, P.M.1    Tisdale, M.J.2
  • 116
    • 0032913372 scopus 로고    scopus 로고
    • Catabolism of adipose tissue by a tumour-produced lipid-mobilising factor
    • S. Khan M.J. Tisdale Catabolism of adipose tissue by a tumour-produced lipid-mobilising factor Int J Cancer 80 3 1999 444 447
    • (1999) Int J Cancer , vol.80 , Issue.3 , pp. 444-447
    • Khan, S.1    Tisdale, M.J.2
  • 117
    • 0037183678 scopus 로고    scopus 로고
    • Effect of a tumour-derived lipid-mobilising factor on glucose and lipid metabolism in vivo
    • S.T. Russell M.J. Tisdale Effect of a tumour-derived lipid-mobilising factor on glucose and lipid metabolism in vivo Br J Cancer 87 5 2002 580 584
    • (2002) Br J Cancer , vol.87 , Issue.5 , pp. 580-584
    • Russell, S.T.1    Tisdale, M.J.2
  • 119
    • 0033153470 scopus 로고    scopus 로고
    • Anorexia and aging: pathophysiology
    • J.E. Morley D.R. Thomas Anorexia and aging: pathophysiology Nutrition 15 6 1999 499 503
    • (1999) Nutrition , vol.15 , Issue.6 , pp. 499-503
    • Morley, J.E.1    Thomas, D.R.2
  • 120
    • 1642292363 scopus 로고    scopus 로고
    • Role of cytokines in regulating feeding behaviour
    • S. Wong J. Pinkney Role of cytokines in regulating feeding behaviour Curr Drug Targets 5 3 2004 251 263
    • (2004) Curr Drug Targets , vol.5 , Issue.3 , pp. 251-263
    • Wong, S.1    Pinkney, J.2
  • 121
    • 0026439353 scopus 로고
    • Changes in food intake and forestomach motility of dwarf goats by recombinant bovine cytokines (IL-1 beta, IL-2) and IFN-gamma
    • A.S. van Miert F. Kaya C.T. van Duin Changes in food intake and forestomach motility of dwarf goats by recombinant bovine cytokines (IL-1 beta, IL-2) and IFN-gamma Physiol Behav 52 5 1992 859 864
    • (1992) Physiol Behav , vol.52 , Issue.5 , pp. 859-864
    • van Miert, A.S.1    Kaya, F.2    van Duin, C.T.3
  • 122
    • 0028179970 scopus 로고
    • Evidence that interleukin-1 beta and tumor necrosis factor inhibit gastric fundus motility via the 5-lipoxygenase pathway
    • P. Montuschi G. Tringali D. Curro Evidence that interleukin-1 beta and tumor necrosis factor inhibit gastric fundus motility via the 5-lipoxygenase pathway Eur J Pharmacol 252 3 1994 253 260
    • (1994) Eur J Pharmacol , vol.252 , Issue.3 , pp. 253-260
    • Montuschi, P.1    Tringali, G.2    Curro, D.3
  • 123
    • 0028950101 scopus 로고
    • Interleukin-1 receptor antagonist displays intrinsic agonist activity on rat gastric fundus motility in vitro
    • P. Montuschi G. Tringali A. Mirtella L. Parente P. Preziosi P. Navarra Interleukin-1 receptor antagonist displays intrinsic agonist activity on rat gastric fundus motility in vitro Eur J Pharmacol 275 1 1995 31 37
    • (1995) Eur J Pharmacol , vol.275 , Issue.1 , pp. 31-37
    • Montuschi, P.1    Tringali, G.2    Mirtella, A.3    Parente, L.4    Preziosi, P.5    Navarra, P.6
  • 124
    • 0028168005 scopus 로고
    • Interleukin-1 beta- and tumour-necrosis-factor-induced inhibition of rat gastric fundus motility in vitro
    • P. Montuschi G. Tringali L. Parente P. Preziosi P. Navarra Interleukin-1 beta- and tumour-necrosis-factor-induced inhibition of rat gastric fundus motility in vitro Pharmacol Res 30 1 1994 25 33
    • (1994) Pharmacol Res , vol.30 , Issue.1 , pp. 25-33
    • Montuschi, P.1    Tringali, G.2    Parente, L.3    Preziosi, P.4    Navarra, P.5
  • 125
    • 0031055457 scopus 로고    scopus 로고
    • Role of central interleukin-1 beta in gastrointestinal motor disturbances induced by lipopolysaccharide in sheep
    • M.A. Plaza J. Fioramonti L. Bueno Role of central interleukin-1 beta in gastrointestinal motor disturbances induced by lipopolysaccharide in sheep Dig Dis Sci 42 2 1997 242 250
    • (1997) Dig Dis Sci , vol.42 , Issue.2 , pp. 242-250
    • Plaza, M.A.1    Fioramonti, J.2    Bueno, L.3
  • 126
    • 0029936861 scopus 로고    scopus 로고
    • Intravenous interleukin-1-beta-induced inhibition of gastric emptying: involvement of central corticotrophin-releasing factor and prostaglandin pathways in rats
    • G. Suto A. Kiraly V. Plourde Y. Tache Intravenous interleukin-1-beta-induced inhibition of gastric emptying: involvement of central corticotrophin-releasing factor and prostaglandin pathways in rats Digestion 57 2 1996 135 140
    • (1996) Digestion , vol.57 , Issue.2 , pp. 135-140
    • Suto, G.1    Kiraly, A.2    Plourde, V.3    Tache, Y.4
  • 127
    • 0028179447 scopus 로고
    • Interleukin 1 beta inhibits gastric emptying in rats: mediation through prostaglandin and corticotropin-releasing factor
    • G. Suto A. Kiraly Y. Tache Interleukin 1 beta inhibits gastric emptying in rats: mediation through prostaglandin and corticotropin-releasing factor Gastroenterology 106 6 1994 1568 1575
    • (1994) Gastroenterology , vol.106 , Issue.6 , pp. 1568-1575
    • Suto, G.1    Kiraly, A.2    Tache, Y.3
  • 128
    • 0029842580 scopus 로고    scopus 로고
    • Anorexia induced by cytokine interactions at pathophysiological concentrations
    • G. Sonti S.E. Ilyin C.R. Plata-Salaman Anorexia induced by cytokine interactions at pathophysiological concentrations Am J Physiol 270 6 Pt 2 1996 R1394 R1402
    • (1996) Am J Physiol , vol.270 , Issue.6 Pt 2 , pp. R1394-R1402
    • Sonti, G.1    Ilyin, S.E.2    Plata-Salaman, C.R.3
  • 129
    • 0029927139 scopus 로고    scopus 로고
    • Neuropeptide Y blocks and reverses interleukin-1 beta-induced anorexia in rats
    • G. Sonti S.E. Ilyin C.R. Plata-Salaman Neuropeptide Y blocks and reverses interleukin-1 beta-induced anorexia in rats Peptides 17 3 1996 517 520
    • (1996) Peptides , vol.17 , Issue.3 , pp. 517-520
    • Sonti, G.1    Ilyin, S.E.2    Plata-Salaman, C.R.3
  • 130
    • 0035822283 scopus 로고    scopus 로고
    • Brain cytokine production and action in anorexia and cachexia
    • C.R. Plata-Salaman Brain cytokine production and action in anorexia and cachexia Cytokine 15 1 2001 1 3
    • (2001) Cytokine , vol.15 , Issue.1 , pp. 1-3
    • Plata-Salaman, C.R.1
  • 131
    • 0029145435 scopus 로고
    • Interactions of the endocrine and immune systems in children and young adults
    • D.A. Papanicolaou G.P. Chrousos Interactions of the endocrine and immune systems in children and young adults Curr Opin Pediatr 7 4 1995 440 444
    • (1995) Curr Opin Pediatr , vol.7 , Issue.4 , pp. 440-444
    • Papanicolaou, D.A.1    Chrousos, G.P.2
  • 132
    • 0033304608 scopus 로고    scopus 로고
    • The differential effect of food intake and beta-adrenergic stimulation on adipose-derived hormones and cytokines in man
    • Z. Orban A.T. Remaley M. Sampson Z. Trajanoski G.P. Chrousos The differential effect of food intake and beta-adrenergic stimulation on adipose-derived hormones and cytokines in man J Clin Endocrinol Metab 84 6 1999 2126 2133
    • (1999) J Clin Endocrinol Metab , vol.84 , Issue.6 , pp. 2126-2133
    • Orban, Z.1    Remaley, A.T.2    Sampson, M.3    Trajanoski, Z.4    Chrousos, G.P.5
  • 134
    • 0027131202 scopus 로고
    • Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans
    • G. Mastorakos G.P. Chrousos J.S. Weber Recombinant interleukin-6 activates the hypothalamic-pituitary-adrenal axis in humans J Clin Endocrinol Metab 77 6 1993 1690 1694
    • (1993) J Clin Endocrinol Metab , vol.77 , Issue.6 , pp. 1690-1694
    • Mastorakos, G.1    Chrousos, G.P.2    Weber, J.S.3
  • 135
    • 33847648484 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase and tumor necrosis factor-alpha in delayed gastric emptying and gastrointestinal transit induced by lipopolysaccharide in mice
    • T. Inada N. Hamano M. Yamada A. Shirane K. Shingu Inducible nitric oxide synthase and tumor necrosis factor-alpha in delayed gastric emptying and gastrointestinal transit induced by lipopolysaccharide in mice Braz J Med Biol Res 39 11 2006 1425 1434
    • (2006) Braz J Med Biol Res , vol.39 , Issue.11 , pp. 1425-1434
    • Inada, T.1    Hamano, N.2    Yamada, M.3    Shirane, A.4    Shingu, K.5
  • 136
    • 34247511154 scopus 로고    scopus 로고
    • Interoceptive ”satiety” signals produced by leptin and CCK
    • S.E. Kanoski E.K. Walls T.L. Davidson Interoceptive ”satiety” signals produced by leptin and CCK Peptides 28 5 2007 988 1002
    • (2007) Peptides , vol.28 , Issue.5 , pp. 988-1002
    • Kanoski, S.E.1    Walls, E.K.2    Davidson, T.L.3
  • 137
    • 0026088560 scopus 로고
    • Corticotropin releasing hormone produces profound anorexigenic effects in the rhesus monkey
    • J.R. Glowa P.W. Gold Corticotropin releasing hormone produces profound anorexigenic effects in the rhesus monkey Neuropeptides 18 1 1991 55 61
    • (1991) Neuropeptides , vol.18 , Issue.1 , pp. 55-61
    • Glowa, J.R.1    Gold, P.W.2
  • 138
    • 4243105079 scopus 로고    scopus 로고
    • Human urocortin 2, a corticotropin-releasing factor (CRF)2 agonist, and ovine CRF, a CRF1 agonist, differentially alter feeding and motor activity
    • E.P. Zorrilla L.E. Reinhardt G.R. Valdez Human urocortin 2, a corticotropin-releasing factor (CRF)2 agonist, and ovine CRF, a CRF1 agonist, differentially alter feeding and motor activity J Pharmacol Exp Ther 310 3 2004 1027 1034
    • (2004) J Pharmacol Exp Ther , vol.310 , Issue.3 , pp. 1027-1034
    • Zorrilla, E.P.1    Reinhardt, L.E.2    Valdez, G.R.3
  • 139
    • 0030026205 scopus 로고    scopus 로고
    • Anorexia in older persons: epidemiology and optimal treatment
    • J.E. Morley Anorexia in older persons: epidemiology and optimal treatment Drugs Aging 8 2 1996 134 155
    • (1996) Drugs Aging , vol.8 , Issue.2 , pp. 134-155
    • Morley, J.E.1
  • 140
    • 0023569324 scopus 로고
    • Neuropeptide Y increases food intake in mice
    • J.E. Morley E.N. Hernandez J.F. Flood Neuropeptide Y increases food intake in mice Am J Physiol 253 3 Pt 2 1987 R516 R522
    • (1987) Am J Physiol , vol.253 , Issue.3 Pt 2 , pp. R516-R522
    • Morley, J.E.1    Hernandez, E.N.2    Flood, J.F.3
  • 141
    • 0022392297 scopus 로고
    • Peptide YY (PYY), a potent orexigenic agent
    • J.E. Morley A.S. Levine M. Grace J. Kneip Peptide YY (PYY), a potent orexigenic agent Brain Res 341 1 1985 200 203
    • (1985) Brain Res , vol.341 , Issue.1 , pp. 200-203
    • Morley, J.E.1    Levine, A.S.2    Grace, M.3    Kneip, J.4
  • 142
    • 0000254266 scopus 로고
    • Effect of neuropeptide Y on ingestive behaviors in the rat
    • J.E. Morley A.S. Levine B.A. Gosnell J. Kneip M. Grace Effect of neuropeptide Y on ingestive behaviors in the rat Am J Physiol 252 3 Pt 2 1987 R599 R609
    • (1987) Am J Physiol , vol.252 , Issue.3 Pt 2 , pp. R599-R609
    • Morley, J.E.1    Levine, A.S.2    Gosnell, B.A.3    Kneip, J.4    Grace, M.5
  • 143
    • 0029002216 scopus 로고
    • Neuropeptide Y and the development of cancer anorexia
    • W.T. Chance A. Balasubramaniam J.E. Fischer Neuropeptide Y and the development of cancer anorexia Ann Surg 221 5 1995 579 587 discussion 87-9
    • (1995) Ann Surg , vol.221 , Issue.5 , pp. 579-587
    • Chance, W.T.1    Balasubramaniam, A.2    Fischer, J.E.3
  • 144
    • 0027384694 scopus 로고
    • Neurotransmitters and food intake
    • W.T. Chance J.E. Fischer Neurotransmitters and food intake Nutrition 9 5 1993 470 471
    • (1993) Nutrition , vol.9 , Issue.5 , pp. 470-471
    • Chance, W.T.1    Fischer, J.E.2
  • 145
    • 0028243943 scopus 로고
    • Hypothalamic concentration and release of neuropeptide Y into microdialysates is reduced in anorectic tumor-bearing rats
    • W.T. Chance A. Balasubramaniam R. Dayal J. Brown J.E. Fischer Hypothalamic concentration and release of neuropeptide Y into microdialysates is reduced in anorectic tumor-bearing rats Life Sci 54 24 1994 1869 1874
    • (1994) Life Sci , vol.54 , Issue.24 , pp. 1869-1874
    • Chance, W.T.1    Balasubramaniam, A.2    Dayal, R.3    Brown, J.4    Fischer, J.E.5
  • 146
    • 0026637310 scopus 로고
    • Evidence for neuropeptide Y mediation of eating produced by food deprivation and for a variant of the Y1 receptor mediating this peptide's effect
    • B.G. Stanley W. Magdalin A. Seirafi M.M. Nguyen S.F. Leibowitz Evidence for neuropeptide Y mediation of eating produced by food deprivation and for a variant of the Y1 receptor mediating this peptide's effect Peptides 13 3 1992 581 587
    • (1992) Peptides , vol.13 , Issue.3 , pp. 581-587
    • Stanley, B.G.1    Magdalin, W.2    Seirafi, A.3    Nguyen, M.M.4    Leibowitz, S.F.5
  • 147
    • 0026460277 scopus 로고
    • Neurochemical-neuroendocrine systems in the brain controlling macronutrient intake and metabolism
    • S.F. Leibowitz Neurochemical-neuroendocrine systems in the brain controlling macronutrient intake and metabolism Trends Neurosci 15 12 1992 491 497
    • (1992) Trends Neurosci , vol.15 , Issue.12 , pp. 491-497
    • Leibowitz, S.F.1
  • 148
    • 0345443373 scopus 로고    scopus 로고
    • Cachexia and obesity: two sides of one coin?
    • A. Inui M.M. Meguid Cachexia and obesity: two sides of one coin? Curr Opin Clin Nutr Metab Care 6 4 2003 395 399
    • (2003) Curr Opin Clin Nutr Metab Care , vol.6 , Issue.4 , pp. 395-399
    • Inui, A.1    Meguid, M.M.2
  • 149
    • 0036198117 scopus 로고    scopus 로고
    • Cancer anorexia-cachexia syndrome: current issues in research and management
    • A. Inui Cancer anorexia-cachexia syndrome: current issues in research and management CA Cancer J Clin 52 2 2002 72 91
    • (2002) CA Cancer J Clin , vol.52 , Issue.2 , pp. 72-91
    • Inui, A.1
  • 151
    • 0028365242 scopus 로고
    • A novel bombesin receptor antagonist selectively blocks the satiety action of peripherally administered bombesin
    • T.C. Kirkham C.A. Walsh J. Gibbs G.P. Smith J. Leban J. McDermed A novel bombesin receptor antagonist selectively blocks the satiety action of peripherally administered bombesin Pharmacol Biochem Behav 48 3 1994 809 811
    • (1994) Pharmacol Biochem Behav , vol.48 , Issue.3 , pp. 809-811
    • Kirkham, T.C.1    Walsh, C.A.2    Gibbs, J.3    Smith, G.P.4    Leban, J.5    McDermed, J.6
  • 152
    • 0026006625 scopus 로고
    • Satiating effect of bombesin is mediated by receptors perfused by celiac artery
    • T.C. Kirkham J. Gibbs G.P. Smith Satiating effect of bombesin is mediated by receptors perfused by celiac artery Am J Physiol 261 3 Pt 2 1991 R614 R618
    • (1991) Am J Physiol , vol.261 , Issue.3 Pt 2 , pp. R614-R618
    • Kirkham, T.C.1    Gibbs, J.2    Smith, G.P.3
  • 153
    • 0025218773 scopus 로고
    • Do peptide-induced changes in feeding occur because of changes in motivation to eat?
    • J.F. Flood A.J. Silver J.E. Morley Do peptide-induced changes in feeding occur because of changes in motivation to eat? Peptides 11 2 1990 265 270
    • (1990) Peptides , vol.11 , Issue.2 , pp. 265-270
    • Flood, J.F.1    Silver, A.J.2    Morley, J.E.3
  • 154
    • 0019956085 scopus 로고
    • Peripherally administered somatostatin reduces feeding by a vagal mediated mechanism
    • A.S. Levine J.E. Morley Peripherally administered somatostatin reduces feeding by a vagal mediated mechanism Pharmacol Biochem Behav 16 6 1982 897 902
    • (1982) Pharmacol Biochem Behav , vol.16 , Issue.6 , pp. 897-902
    • Levine, A.S.1    Morley, J.E.2
  • 155
  • 156
    • 0025807569 scopus 로고
    • Hepatic portal glucagon infusion decreases spontaneous meal size in rats
    • J. Le Sauter N. Geary Hepatic portal glucagon infusion decreases spontaneous meal size in rats Am J Physiol 261 1 Pt 2 1991 R154 R161
    • (1991) Am J Physiol , vol.261 , Issue.1 Pt 2 , pp. R154-R161
    • Le Sauter, J.1    Geary, N.2
  • 157
    • 0027530401 scopus 로고
    • Glucagon acts in the liver to control spontaneous meal size in rats
    • N. Geary J. Le Sauter U. Noh Glucagon acts in the liver to control spontaneous meal size in rats Am J Physiol 264 1 Pt 2 1993 R116 R122
    • (1993) Am J Physiol , vol.264 , Issue.1 Pt 2 , pp. R116-R122
    • Geary, N.1    Le Sauter, J.2    Noh, U.3
  • 158
    • 0021720147 scopus 로고
    • Gut peptides and postprandial satiety
    • G.P. Smith J. Gibbs Gut peptides and postprandial satiety Fed Proc 43 14 1984 2889 2892
    • (1984) Fed Proc , vol.43 , Issue.14 , pp. 2889-2892
    • Smith, G.P.1    Gibbs, J.2
  • 159
    • 0020130661 scopus 로고
    • Cholecystokinin suppresses food intake by inhibiting gastric emptying
    • T.H. Moran P.R. McHugh Cholecystokinin suppresses food intake by inhibiting gastric emptying Am J Physiol 242 5 1982 R491 R497
    • (1982) Am J Physiol , vol.242 , Issue.5 , pp. R491-R497
    • Moran, T.H.1    McHugh, P.R.2
  • 160
    • 0021023795 scopus 로고
    • Involvement of dynorphin and the kappa opioid receptor in feeding
    • J.E. Morley A.S. Levine Involvement of dynorphin and the kappa opioid receptor in feeding Peptides 4 6 1983 797 800
    • (1983) Peptides , vol.4 , Issue.6 , pp. 797-800
    • Morley, J.E.1    Levine, A.S.2
  • 161
    • 0030968077 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced nitric oxide and cytokine production by ultralow concentrations of dynorphins in mixed glia cultures
    • L.Y. Kong M.K. McMillian P.M. Hudson L. Jin J.S. Hong Inhibition of lipopolysaccharide-induced nitric oxide and cytokine production by ultralow concentrations of dynorphins in mixed glia cultures J Pharmacol Exp Ther 280 1 1997 61 66
    • (1997) J Pharmacol Exp Ther , vol.280 , Issue.1 , pp. 61-66
    • Kong, L.Y.1    McMillian, M.K.2    Hudson, P.M.3    Jin, L.4    Hong, J.S.5
  • 162
    • 0029091160 scopus 로고
    • Upregulation of HIV-1 expression in cocultures of chronically infected promonocytes and human brain cells by dynorphin
    • C.C. Chao G. Gekker S. Hu W.S. Sheng P.S. Portoghese P.K. Peterson Upregulation of HIV-1 expression in cocultures of chronically infected promonocytes and human brain cells by dynorphin Biochem Pharmacol 50 5 1995 715 722
    • (1995) Biochem Pharmacol , vol.50 , Issue.5 , pp. 715-722
    • Chao, C.C.1    Gekker, G.2    Hu, S.3    Sheng, W.S.4    Portoghese, P.S.5    Peterson, P.K.6
  • 165
    • 0028916793 scopus 로고
    • Nitric oxide synthase inhibition and food intake: effects on motivation to eat and in female mice
    • J.E. Morley S.A. Farr M.D. Suarez J.F. Flood Nitric oxide synthase inhibition and food intake: effects on motivation to eat and in female mice Pharmacol Biochem Behav 50 3 1995 369 373
    • (1995) Pharmacol Biochem Behav , vol.50 , Issue.3 , pp. 369-373
    • Morley, J.E.1    Farr, S.A.2    Suarez, M.D.3    Flood, J.F.4
  • 166
    • 0025776498 scopus 로고
    • Evidence that nitric oxide modulates food intake in mice
    • J.E. Morley J.F. Flood Evidence that nitric oxide modulates food intake in mice Life Sci 49 10 1991 707 711
    • (1991) Life Sci , vol.49 , Issue.10 , pp. 707-711
    • Morley, J.E.1    Flood, J.F.2
  • 167
    • 34447512947 scopus 로고    scopus 로고
    • Signals generating anorexia during acute illness
    • W. Langhans Signals generating anorexia during acute illness Proc Nutr Soc 66 3 2007 321 330
    • (2007) Proc Nutr Soc , vol.66 , Issue.3 , pp. 321-330
    • Langhans, W.1
  • 168
    • 34250667431 scopus 로고    scopus 로고
    • Melanocortin interventions in cachexia: how soon from bench to bedside?
    • M.D. DeBoer Melanocortin interventions in cachexia: how soon from bench to bedside? Curr Opin Clin Nutr Metab Care 10 4 2007 457 462
    • (2007) Curr Opin Clin Nutr Metab Care , vol.10 , Issue.4 , pp. 457-462
    • DeBoer, M.D.1
  • 169
    • 0024342451 scopus 로고
    • Anorexia induced by interleukin 1: involvement of corticotropin-releasing factor
    • A. Uehara C. Sekiya Y. Takasugi M. Namiki A. Arimura Anorexia induced by interleukin 1: involvement of corticotropin-releasing factor Am J Physiol 257 3 Pt 2 1989 R613 R617
    • (1989) Am J Physiol , vol.257 , Issue.3 Pt 2 , pp. R613-R617
    • Uehara, A.1    Sekiya, C.2    Takasugi, Y.3    Namiki, M.4    Arimura, A.5
  • 170
    • 0027249438 scopus 로고
    • The role of cholecystokinin in interleukin-1-induced anorexia
    • J.M. Daun D.O. McCarthy The role of cholecystokinin in interleukin-1-induced anorexia Physiol Behav 54 2 1993 237 241
    • (1993) Physiol Behav , vol.54 , Issue.2 , pp. 237-241
    • Daun, J.M.1    McCarthy, D.O.2
  • 171
    • 0035159558 scopus 로고    scopus 로고
    • Intracerebroventricular injection of fusaric acid attenuates the anorexia by glucagon-like peptide-1 in the neonatal chick
    • T. Bungo S.I. Kawakami A. Ohgushi Intracerebroventricular injection of fusaric acid attenuates the anorexia by glucagon-like peptide-1 in the neonatal chick Pharmacol Biochem Behav 70 2-3 2001 251 255
    • (2001) Pharmacol Biochem Behav , vol.70 , Issue.2-3 , pp. 251-255
    • Bungo, T.1    Kawakami, S.I.2    Ohgushi, A.3
  • 172
    • 11144244302 scopus 로고    scopus 로고
    • The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice
    • J.L. Lachey D.A. D'Alessio L. Rinaman J.K. Elmquist D.J. Drucker R.J. Seeley The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice Endocrinology 146 1 2005 458 462
    • (2005) Endocrinology , vol.146 , Issue.1 , pp. 458-462
    • Lachey, J.L.1    D'Alessio, D.A.2    Rinaman, L.3    Elmquist, J.K.4    Drucker, D.J.5    Seeley, R.J.6
  • 173
    • 0346655092 scopus 로고    scopus 로고
    • The hypothalamus is involved in the anorexic effect of glucagon-like peptide-1 in chicks
    • T. Tachibana K. Hirofuji M. Matsumoto The hypothalamus is involved in the anorexic effect of glucagon-like peptide-1 in chicks Comp Biochem Physiol A Mol Integr Physiol 137 1 2004 183 188
    • (2004) Comp Biochem Physiol A Mol Integr Physiol , vol.137 , Issue.1 , pp. 183-188
    • Tachibana, T.1    Hirofuji, K.2    Matsumoto, M.3
  • 174
    • 0242694049 scopus 로고    scopus 로고
    • Intracerebroventricular administration of insulin and glucose inhibits the anorectic action of leptin in rats
    • N. Fujita H. Sakamaki S. Uotani Intracerebroventricular administration of insulin and glucose inhibits the anorectic action of leptin in rats Exp Biol Med (Maywood) 228 10 2003 1156 1161
    • (2003) Exp Biol Med (Maywood) , vol.228 , Issue.10 , pp. 1156-1161
    • Fujita, N.1    Sakamaki, H.2    Uotani, S.3
  • 175
    • 1042279507 scopus 로고    scopus 로고
    • Plasma leptin, insulin and free tryptophan contribute to cytokine-induced anorexia
    • T. Sato A. Laviano M.M. Meguid F. Rossi-Fanelli Plasma leptin, insulin and free tryptophan contribute to cytokine-induced anorexia Adv Exp Med Biol 527 2003 233 239
    • (2003) Adv Exp Med Biol , vol.527 , pp. 233-239
    • Sato, T.1    Laviano, A.2    Meguid, M.M.3    Rossi-Fanelli, F.4
  • 176
    • 34250878349 scopus 로고    scopus 로고
    • Time-course changes of hormones and cytokines by lipopolysaccharide and its relation with anorexia
    • Y.W. Kim K.H. Kim D.K. Ahn Time-course changes of hormones and cytokines by lipopolysaccharide and its relation with anorexia J Physiol Sci 57 3 2007 159 165
    • (2007) J Physiol Sci , vol.57 , Issue.3 , pp. 159-165
    • Kim, Y.W.1    Kim, K.H.2    Ahn, D.K.3
  • 177
    • 0024358876 scopus 로고
    • Indomethacin blocks the anorexic action of interleukin-1
    • A. Uehara Y. Ishikawa T. Okumura Indomethacin blocks the anorexic action of interleukin-1 Eur J Pharmacol 170 3 1989 257 260
    • (1989) Eur J Pharmacol , vol.170 , Issue.3 , pp. 257-260
    • Uehara, A.1    Ishikawa, Y.2    Okumura, T.3
  • 178
    • 0024412884 scopus 로고
    • Interleukin-1 inhibits the secretion of gastric acid in rats: possible involvement of prostaglandin
    • A. Uehara T. Okumura C. Sekiya K. Okamura Y. Takasugi M. Namiki Interleukin-1 inhibits the secretion of gastric acid in rats: possible involvement of prostaglandin Biochem Biophys Res Commun 162 3 1989 1578 1584
    • (1989) Biochem Biophys Res Commun , vol.162 , Issue.3 , pp. 1578-1584
    • Uehara, A.1    Okumura, T.2    Sekiya, C.3    Okamura, K.4    Takasugi, Y.5    Namiki, M.6
  • 179
    • 0027176336 scopus 로고
    • Interleukin-1 beta augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus
    • F. Shintani S. Kanba T. Nakaki Interleukin-1 beta augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus J Neurosci 13 8 1993 3574 3581
    • (1993) J Neurosci , vol.13 , Issue.8 , pp. 3574-3581
    • Shintani, F.1    Kanba, S.2    Nakaki, T.3
  • 180
    • 34249984987 scopus 로고    scopus 로고
    • 5-HT(2C) receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice
    • E.M. Somerville J.M. Horwood M.D. Lee G.A. Kennett P.G. Clifton 5-HT(2C) receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice Eur J Neurosci 25 10 2007 3115 3124
    • (2007) Eur J Neurosci , vol.25 , Issue.10 , pp. 3115-3124
    • Somerville, E.M.1    Horwood, J.M.2    Lee, M.D.3    Kennett, G.A.4    Clifton, P.G.5
  • 181
    • 0038051130 scopus 로고    scopus 로고
    • Central serotonin and melanocortin pathways regulating energy homeostasis
    • L.K. Heisler M.A. Cowley T. Kishi Central serotonin and melanocortin pathways regulating energy homeostasis Ann N Y Acad Sci 994 2003 169 174
    • (2003) Ann N Y Acad Sci , vol.994 , pp. 169-174
    • Heisler, L.K.1    Cowley, M.A.2    Kishi, T.3
  • 182
    • 33746632050 scopus 로고    scopus 로고
    • To eat or not to eat; regulation by the melanocortin system
    • J.J. Hillebrand M.J. Kas R.A. Adan To eat or not to eat; regulation by the melanocortin system Physiol Behav 89 1 2006 97 102
    • (2006) Physiol Behav , vol.89 , Issue.1 , pp. 97-102
    • Hillebrand, J.J.1    Kas, M.J.2    Adan, R.A.3
  • 183
    • 0030928715 scopus 로고    scopus 로고
    • Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
    • C.C. Cheung D.K. Clifton R.A. Steiner Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus Endocrinology 138 10 1997 4489 4492
    • (1997) Endocrinology , vol.138 , Issue.10 , pp. 4489-4492
    • Cheung, C.C.1    Clifton, D.K.2    Steiner, R.A.3
  • 184
    • 0035786901 scopus 로고    scopus 로고
    • Central melanocortins and the regulation of weight during acute and chronic disease
    • D.L. Marks R.D. Cone Central melanocortins and the regulation of weight during acute and chronic disease Recent Prog Horm Res 56 2001 359 375
    • (2001) Recent Prog Horm Res , vol.56 , pp. 359-375
    • Marks, D.L.1    Cone, R.D.2
  • 185
    • 34547791859 scopus 로고    scopus 로고
    • Effects of pro-opiomelanocortin (POMC) on food intake and body weight: mechanisms and therapeutic potential?
    • A.P. Coll Effects of pro-opiomelanocortin (POMC) on food intake and body weight: mechanisms and therapeutic potential? Clin Sci (Lond) 113 4 2007 171 182
    • (2007) Clin Sci (Lond) , vol.113 , Issue.4 , pp. 171-182
    • Coll, A.P.1
  • 186
    • 0031763336 scopus 로고    scopus 로고
    • Cytokine regulation of the rat proopiomelanocortin gene expression in AtT-20 cells
    • M. Katahira Y. Iwasaki Y. Aoki Y. Oiso H. Saito Cytokine regulation of the rat proopiomelanocortin gene expression in AtT-20 cells Endocrinology 139 5 1998 2414 2422
    • (1998) Endocrinology , vol.139 , Issue.5 , pp. 2414-2422
    • Katahira, M.1    Iwasaki, Y.2    Aoki, Y.3    Oiso, Y.4    Saito, H.5
  • 187
    • 0032915413 scopus 로고    scopus 로고
    • Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting
    • T.M. Mizuno C.V. Mobbs Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting Endocrinology 140 2 1999 814 817
    • (1999) Endocrinology , vol.140 , Issue.2 , pp. 814-817
    • Mizuno, T.M.1    Mobbs, C.V.2
  • 188
    • 20444497662 scopus 로고    scopus 로고
    • Role of leptin and melanocortin signaling in uremia-associated cachexia
    • W. Cheung P.X. Yu B.M. Little R.D. Cone D.L. Marks R.H. Mak Role of leptin and melanocortin signaling in uremia-associated cachexia J Clin Invest 115 6 2005 1659 1665
    • (2005) J Clin Invest , vol.115 , Issue.6 , pp. 1659-1665
    • Cheung, W.1    Yu, P.X.2    Little, B.M.3    Cone, R.D.4    Marks, D.L.5    Mak, R.H.6
  • 189
    • 0035942777 scopus 로고    scopus 로고
    • Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
    • M.A. Cowley J.L. Smart M. Rubinstein Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus Nature 411 6836 2001 480 484
    • (2001) Nature , vol.411 , Issue.6836 , pp. 480-484
    • Cowley, M.A.1    Smart, J.L.2    Rubinstein, M.3
  • 190
    • 1842529267 scopus 로고    scopus 로고
    • Rapid rewiring of arcuate nucleus feeding circuits by leptin
    • S. Pinto A.G. Roseberry H. Liu Rapid rewiring of arcuate nucleus feeding circuits by leptin Science 304 5667 2004 110 115
    • (2004) Science , vol.304 , Issue.5667 , pp. 110-115
    • Pinto, S.1    Roseberry, A.G.2    Liu, H.3
  • 191
    • 0031888157 scopus 로고    scopus 로고
    • Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin
    • T.M. Mizuno S.P. Kleopoulos H.T. Bergen J.L. Roberts C.A. Priest C.V. Mobbs Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin Diabetes 47 2 1998 294 297
    • (1998) Diabetes , vol.47 , Issue.2 , pp. 294-297
    • Mizuno, T.M.1    Kleopoulos, S.P.2    Bergen, H.T.3    Roberts, J.L.4    Priest, C.A.5    Mobbs, C.V.6
  • 192
    • 0033559446 scopus 로고    scopus 로고
    • Role of the CNS melanocortin system in the response to overfeeding
    • M.M. Hagan P.A. Rushing M.W. Schwartz Role of the CNS melanocortin system in the response to overfeeding J Neurosci 19 6 1999 2362 2367
    • (1999) J Neurosci , vol.19 , Issue.6 , pp. 2362-2367
    • Hagan, M.M.1    Rushing, P.A.2    Schwartz, M.W.3
  • 193
    • 34548573251 scopus 로고    scopus 로고
    • Orexin expression is regulated by alpha-melanocyte-stimulating hormone
    • M. Lopez R. Lage Y.C. Tung Orexin expression is regulated by alpha-melanocyte-stimulating hormone J Neuroendocrinol 19 9 2007 703 707
    • (2007) J Neuroendocrinol , vol.19 , Issue.9 , pp. 703-707
    • Lopez, M.1    Lage, R.2    Tung, Y.C.3
  • 194
    • 0000739329 scopus 로고
    • alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain
    • D.M. Jacobowitz T.L. O'Donohue alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain Proc Natl Acad Sci U S A 75 12 1978 6300 6304
    • (1978) Proc Natl Acad Sci U S A , vol.75 , Issue.12 , pp. 6300-6304
    • Jacobowitz, D.M.1    O'Donohue, T.L.2
  • 195
    • 0030889192 scopus 로고    scopus 로고
    • Targeted disruption of the melanocortin-4 receptor results in obesity in mice
    • D. Huszar C.A. Lynch V. Fairchild-Huntress Targeted disruption of the melanocortin-4 receptor results in obesity in mice Cell 88 1 1997 131 141
    • (1997) Cell , vol.88 , Issue.1 , pp. 131-141
    • Huszar, D.1    Lynch, C.A.2    Fairchild-Huntress, V.3
  • 196
    • 33644554532 scopus 로고    scopus 로고
    • Leptin and inflammation-associated cachexia in chronic kidney disease
    • R.H. Mak W. Cheung R.D. Cone D.L. Marks Leptin and inflammation-associated cachexia in chronic kidney disease Kidney Int 69 5 2006 794 797
    • (2006) Kidney Int , vol.69 , Issue.5 , pp. 794-797
    • Mak, R.H.1    Cheung, W.2    Cone, R.D.3    Marks, D.L.4
  • 197
    • 33750970840 scopus 로고    scopus 로고
    • Energy homeostasis and cachexia in chronic kidney disease
    • R.H. Mak W. Cheung Energy homeostasis and cachexia in chronic kidney disease Pediatr Nephrol 21 12 2006 1807 1814
    • (2006) Pediatr Nephrol , vol.21 , Issue.12 , pp. 1807-1814
    • Mak, R.H.1    Cheung, W.2
  • 198
    • 34548502188 scopus 로고    scopus 로고
    • Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice
    • W.W. Cheung H.J. Kuo S. Markison Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice J Am Soc Nephrol 18 9 2007 2517 2524
    • (2007) J Am Soc Nephrol , vol.18 , Issue.9 , pp. 2517-2524
    • Cheung, W.W.1    Kuo, H.J.2    Markison, S.3
  • 199
    • 0034810577 scopus 로고    scopus 로고
    • Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan
    • M. Diksic S.N. Young Study of the brain serotonergic system with labeled alpha-methyl-L-tryptophan J Neurochem 78 6 2001 1185 1200
    • (2001) J Neurochem , vol.78 , Issue.6 , pp. 1185-1200
    • Diksic, M.1    Young, S.N.2
  • 201
    • 0037378707 scopus 로고    scopus 로고
    • Involvement of plasma leptin, insulin and free tryptophan in cytokine-induced anorexia
    • T. Sato A. Laviano M.M. Meguid C. Chen F. Rossi-Fanelli K. Hatakeyama Involvement of plasma leptin, insulin and free tryptophan in cytokine-induced anorexia Clin Nutr 22 2 2003 139 146
    • (2003) Clin Nutr , vol.22 , Issue.2 , pp. 139-146
    • Sato, T.1    Laviano, A.2    Meguid, M.M.3    Chen, C.4    Rossi-Fanelli, F.5    Hatakeyama, K.6
  • 204
    • 0028168742 scopus 로고
    • Cytokines, tryptophan and anorexia in cancer patients before and after surgical tumor ablation
    • C. Cangiano U. Testa M. Muscaritoli Cytokines, tryptophan and anorexia in cancer patients before and after surgical tumor ablation Anticancer Res 14 3B 1994 1451 1455
    • (1994) Anticancer Res , vol.14 , Issue.3B , pp. 1451-1455
    • Cangiano, C.1    Testa, U.2    Muscaritoli, M.3
  • 205
    • 0027358204 scopus 로고
    • Infection as a stressor: a cytokine-mediated activation of the hypothalamo-pituitary-adrenal axis?
    • A.J. Dunn Infection as a stressor: a cytokine-mediated activation of the hypothalamo-pituitary-adrenal axis? Ciba Found Symp 172 1993 226 239 discussion 39-42
    • (1993) Ciba Found Symp , vol.172 , pp. 226-239
    • Dunn, A.J.1
  • 207
    • 0031409709 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-adrenal axis function, psychopathological traits, and natural killer (NK) cell activity in anorexia nervosa
    • A.H. Staurenghi R.G. Masera P. Prolo Hypothalamic-pituitary-adrenal axis function, psychopathological traits, and natural killer (NK) cell activity in anorexia nervosa Psychoneuroendocrinology 22 8 1997 575 590
    • (1997) Psychoneuroendocrinology , vol.22 , Issue.8 , pp. 575-590
    • Staurenghi, A.H.1    Masera, R.G.2    Prolo, P.3
  • 208
    • 0031439207 scopus 로고    scopus 로고
    • Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the CNS of mice
    • J. Raber R.D. O'Shea F.E. Bloom I.L. Campbell Modulation of hypothalamic-pituitary-adrenal function by transgenic expression of interleukin-6 in the CNS of mice J Neurosci 17 24 1997 9473 9480
    • (1997) J Neurosci , vol.17 , Issue.24 , pp. 9473-9480
    • Raber, J.1    O'Shea, R.D.2    Bloom, F.E.3    Campbell, I.L.4
  • 209
    • 0142156632 scopus 로고    scopus 로고
    • What we have learned about cachexia in gastrointestinal cancer
    • J.A. Palesty S.J. Dudrick What we have learned about cachexia in gastrointestinal cancer Dig Dis 21 3 2003 198 213
    • (2003) Dig Dis , vol.21 , Issue.3 , pp. 198-213
    • Palesty, J.A.1    Dudrick, S.J.2
  • 210
    • 0021833470 scopus 로고
    • Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung cancer
    • W.K. Evans R. Makuch G.H. Clamon Limited impact of total parenteral nutrition on nutritional status during treatment for small cell lung cancer Cancer Res 45 7 1985 3347 3353
    • (1985) Cancer Res , vol.45 , Issue.7 , pp. 3347-3353
    • Evans, W.K.1    Makuch, R.2    Clamon, G.H.3
  • 211
    • 34548367550 scopus 로고    scopus 로고
    • Metabolic frailty in malnourished heart failure patients
    • A. Gualco C. Opasich S. Brazzo Metabolic frailty in malnourished heart failure patients [in Italian] Monaldi Arch Chest Dis 68 2 2007 115 120
    • (2007) Monaldi Arch Chest Dis , vol.68 , Issue.2 , pp. 115-120
    • Gualco, A.1    Opasich, C.2    Brazzo, S.3
  • 213
    • 33646902419 scopus 로고    scopus 로고
    • Inflammatory markers and loss of muscle mass (sarcopenia) and strength
    • L.A. Schaap S.M. Pluijm D.J. Deeg M. Visser Inflammatory markers and loss of muscle mass (sarcopenia) and strength Am J Med 119 6 2006 526 e9 526 e17
    • (2006) Am J Med , vol.119 , Issue.6 , pp. 526 e9-526 e17
    • Schaap, L.A.1    Pluijm, S.M.2    Deeg, D.J.3    Visser, M.4
  • 214
    • 0033523019 scopus 로고    scopus 로고
    • Interleukin-10 receptor signaling through the JAK-STAT pathway: Requirement for two distinct receptor-derived signals for anti-inflammatory action
    • J.K. Riley K. Takeda S. Akira R.D. Schreiber Interleukin-10 receptor signaling through the JAK-STAT pathway Requirement for two distinct receptor-derived signals for anti-inflammatory action J Biol Chem 274 23 1999 16513 16521
    • (1999) J Biol Chem , vol.274 , Issue.23 , pp. 16513-16521
    • Riley, J.K.1    Takeda, K.2    Akira, S.3    Schreiber, R.D.4
  • 215
    • 0033519870 scopus 로고    scopus 로고
    • Cachexia in cancer: disturbances in the protein and aminoacid metabolism
    • I. de Blaauw N.E. Deutz M.F. von Meyenfeldt Cachexia in cancer: disturbances in the protein and aminoacid metabolism [in Dutch] Ned Tijdschr Geneeskd 143 27 1999 1408 1413
    • (1999) Ned Tijdschr Geneeskd , vol.143 , Issue.27 , pp. 1408-1413
    • de Blaauw, I.1    Deutz, N.E.2    von Meyenfeldt, M.F.3
  • 217
    • 0029875442 scopus 로고    scopus 로고
    • Glutamine deficiency as a cause of human immunodeficiency virus wasting
    • J.K. Shabert D.W. Wilmore Glutamine deficiency as a cause of human immunodeficiency virus wasting Med Hypotheses 46 3 1996 252 256
    • (1996) Med Hypotheses , vol.46 , Issue.3 , pp. 252-256
    • Shabert, J.K.1    Wilmore, D.W.2
  • 218
    • 33845565186 scopus 로고    scopus 로고
    • Nutrition, metabolism, and the complex pathophysiology of cachexia in chronic heart failure
    • S. von Haehling W. Doehner S.D. Anker Nutrition, metabolism, and the complex pathophysiology of cachexia in chronic heart failure Cardiovasc Res 73 2 2007 298 309
    • (2007) Cardiovasc Res , vol.73 , Issue.2 , pp. 298-309
    • von Haehling, S.1    Doehner, W.2    Anker, S.D.3
  • 219
    • 33644984957 scopus 로고    scopus 로고
    • Identification of major cellular proteins synthesized in response to interleukin-1 and interleukin-6 in human hepatoma HepG2 cells
    • E. Bonar A. Dubin A. Bierczynska-Krzysik Identification of major cellular proteins synthesized in response to interleukin-1 and interleukin-6 in human hepatoma HepG2 cells Cytokine 33 2 2006 111 117
    • (2006) Cytokine , vol.33 , Issue.2 , pp. 111-117
    • Bonar, E.1    Dubin, A.2    Bierczynska-Krzysik, A.3
  • 220
    • 20144379879 scopus 로고    scopus 로고
    • Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins
    • C. Arnaud F. Burger S. Steffens Statins reduce interleukin-6-induced C-reactive protein in human hepatocytes: new evidence for direct antiinflammatory effects of statins Arterioscler Thromb Vasc Biol 25 6 2005 1231 1236
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.6 , pp. 1231-1236
    • Arnaud, C.1    Burger, F.2    Steffens, S.3
  • 221
    • 34250651616 scopus 로고    scopus 로고
    • Hepatic mitochondrial function and brain tumours
    • D.L. Pouliquen Hepatic mitochondrial function and brain tumours Curr Opin Clin Nutr Metab Care 10 4 2007 475 479
    • (2007) Curr Opin Clin Nutr Metab Care , vol.10 , Issue.4 , pp. 475-479
    • Pouliquen, D.L.1
  • 223
    • 12744268593 scopus 로고    scopus 로고
    • Activation of UCPs gene expression in skeletal muscle can be independent on both circulating fatty acids and food intake: Involvement of ROS in a model of mouse cancer cachexia
    • S. Busquets V. Almendro E. Barreiro M. Figueras J.M. Argiles F.J. Lopez-Soriano Activation of UCPs gene expression in skeletal muscle can be independent on both circulating fatty acids and food intake Involvement of ROS in a model of mouse cancer cachexia FEBS Lett 579 3 2005 717 722
    • (2005) FEBS Lett , vol.579 , Issue.3 , pp. 717-722
    • Busquets, S.1    Almendro, V.2    Barreiro, E.3    Figueras, M.4    Argiles, J.M.5    Lopez-Soriano, F.J.6
  • 225
    • 0032407443 scopus 로고    scopus 로고
    • In the rat, tumor necrosis factor alpha administration results in an increase in both UCP2 and UCP3 mRNAs in skeletal muscle: a possible mechanism for cytokine-induced thermogenesis?
    • S. Busquets D. Sanchis B. Alvarez D. Ricquier F.J. Lopez-Soriano J.M. Argiles In the rat, tumor necrosis factor alpha administration results in an increase in both UCP2 and UCP3 mRNAs in skeletal muscle: a possible mechanism for cytokine-induced thermogenesis? FEBS Lett 440 3 1998 348 350
    • (1998) FEBS Lett , vol.440 , Issue.3 , pp. 348-350
    • Busquets, S.1    Sanchis, D.2    Alvarez, B.3    Ricquier, D.4    Lopez-Soriano, F.J.5    Argiles, J.M.6
  • 226
    • 0030593939 scopus 로고    scopus 로고
    • Mechanisms of muscle wasting: The role of the ubiquitin-proteasome pathway
    • W.E. Mitch A.L. Goldberg Mechanisms of muscle wasting The role of the ubiquitin-proteasome pathway N Engl J Med 335 25 1996 1897 1905
    • (1996) N Engl J Med , vol.335 , Issue.25 , pp. 1897-1905
    • Mitch, W.E.1    Goldberg, A.L.2
  • 227
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Z.J. Chen Ubiquitin signalling in the NF-kappaB pathway Nat Cell Biol 7 8 2005 758 765
    • (2005) Nat Cell Biol , vol.7 , Issue.8 , pp. 758-765
    • Chen, Z.J.1
  • 228
    • 85047694453 scopus 로고    scopus 로고
    • Increased muscle proteasome activity correlates with disease severity in gastric cancer patients
    • M. Bossola M. Muscaritoli P. Costelli Increased muscle proteasome activity correlates with disease severity in gastric cancer patients Ann Surg 237 3 2003 384 389
    • (2003) Ann Surg , vol.237 , Issue.3 , pp. 384-389
    • Bossola, M.1    Muscaritoli, M.2    Costelli, P.3
  • 229
    • 0036382762 scopus 로고    scopus 로고
    • Anticytokine treatment prevents the increase in the activity of ATP-ubiquitin- and Ca(2+)-dependent proteolytic systems in the muscle of tumour-bearing rats
    • P. Costelli M. Bossola M. Muscaritoli Anticytokine treatment prevents the increase in the activity of ATP-ubiquitin- and Ca(2+)-dependent proteolytic systems in the muscle of tumour-bearing rats Cytokine 19 1 2002 1 5
    • (2002) Cytokine , vol.19 , Issue.1 , pp. 1-5
    • Costelli, P.1    Bossola, M.2    Muscaritoli, M.3
  • 231
    • 9144264926 scopus 로고    scopus 로고
    • Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation
    • S.M. Wyke S.T. Russell M.J. Tisdale Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation Br J Cancer 91 9 2004 1742 1750
    • (2004) Br J Cancer , vol.91 , Issue.9 , pp. 1742-1750
    • Wyke, S.M.1    Russell, S.T.2    Tisdale, M.J.3
  • 232
    • 0026909816 scopus 로고
    • The Sir David Cuthbertson Medal Lecture 1991: The mechanisms and treatment of weight loss in cancer
    • K.C. Fearon The Sir David Cuthbertson Medal Lecture 1991 The mechanisms and treatment of weight loss in cancer Proc Nutr Soc 51 2 1992 251 265
    • (1992) Proc Nutr Soc , vol.51 , Issue.2 , pp. 251-265
    • Fearon, K.C.1
  • 233
    • 0023949741 scopus 로고
    • Effects of tumor necrosis factor (TNF) on lipolytic activities of rat heart
    • W.C. Hulsmann M.L. Dubelaar Effects of tumor necrosis factor (TNF) on lipolytic activities of rat heart Mol Cell Biochem 79 2 1988 147 151
    • (1988) Mol Cell Biochem , vol.79 , Issue.2 , pp. 147-151
    • Hulsmann, W.C.1    Dubelaar, M.L.2
  • 234
    • 0026733835 scopus 로고
    • Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanism
    • I. Hardardottir W. Doerrler K.R. Feingold C. Grunfeld Cytokines stimulate lipolysis and decrease lipoprotein lipase activity in cultured fat cells by a prostaglandin independent mechanism Biochem Biophys Res Commun 186 1 1992 237 243
    • (1992) Biochem Biophys Res Commun , vol.186 , Issue.1 , pp. 237-243
    • Hardardottir, I.1    Doerrler, W.2    Feingold, K.R.3    Grunfeld, C.4
  • 235
    • 0028225295 scopus 로고
    • Leukemia inhibitory factor induces changes in lipid metabolism in cultured adipocytes
    • M.K. Marshall W. Doerrler K.R. Feingold C. Grunfeld Leukemia inhibitory factor induces changes in lipid metabolism in cultured adipocytes Endocrinology 135 1 1994 141 147
    • (1994) Endocrinology , vol.135 , Issue.1 , pp. 141-147
    • Marshall, M.K.1    Doerrler, W.2    Feingold, K.R.3    Grunfeld, C.4
  • 236
    • 0027982085 scopus 로고
    • Cytokines induce catabolic effects in cultured adipocytes by multiple mechanisms
    • W. Doerrler K.R. Feingold C. Grunfeld Cytokines induce catabolic effects in cultured adipocytes by multiple mechanisms Cytokine 6 5 1994 478 484
    • (1994) Cytokine , vol.6 , Issue.5 , pp. 478-484
    • Doerrler, W.1    Feingold, K.R.2    Grunfeld, C.3
  • 237
    • 0026529589 scopus 로고
    • Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis
    • K.R. Feingold W. Doerrler C.A. Dinarello W. Fiers C. Grunfeld Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis Endocrinology 130 1 1992 10 16
    • (1992) Endocrinology , vol.130 , Issue.1 , pp. 10-16
    • Feingold, K.R.1    Doerrler, W.2    Dinarello, C.A.3    Fiers, W.4    Grunfeld, C.5
  • 238
    • 0026637135 scopus 로고
    • Tumor necrosis factor, interleukin, and interferon induced changes in lipid metabolism as part of host defense
    • C. Grunfeld K.R. Feingold Tumor necrosis factor, interleukin, and interferon induced changes in lipid metabolism as part of host defense Proc Soc Exp Biol Med 200 2 1992 224 227
    • (1992) Proc Soc Exp Biol Med , vol.200 , Issue.2 , pp. 224-227
    • Grunfeld, C.1    Feingold, K.R.2
  • 239
    • 0027956188 scopus 로고
    • Characterization of differentiation factor/leukaemia inhibitory factor effect on lipoprotein lipase activity and mRNA in 3T3-L1 adipocytes
    • M. Berg D.L. Fraker H.R. Alexander Characterization of differentiation factor/leukaemia inhibitory factor effect on lipoprotein lipase activity and mRNA in 3T3-L1 adipocytes Cytokine 6 4 1994 425 432
    • (1994) Cytokine , vol.6 , Issue.4 , pp. 425-432
    • Berg, M.1    Fraker, D.L.2    Alexander, H.R.3
  • 241
    • 0025817728 scopus 로고
    • Lipid mobilising factors specifically associated with cancer cachexia
    • S.A. Beck M.J. Tisdale Lipid mobilising factors specifically associated with cancer cachexia Br J Cancer 63 6 1991 846 850
    • (1991) Br J Cancer , vol.63 , Issue.6 , pp. 846-850
    • Beck, S.A.1    Tisdale, M.J.2
  • 243
    • 0033994155 scopus 로고    scopus 로고
    • Beta-adrenoceptor activity and resting energy metabolism in weight losing cancer patients
    • A. Hyltander P. Daneryd R. Sandstrom U. Korner K. Lundholm Beta-adrenoceptor activity and resting energy metabolism in weight losing cancer patients Eur J Cancer 36 3 2000 330 334
    • (2000) Eur J Cancer , vol.36 , Issue.3 , pp. 330-334
    • Hyltander, A.1    Daneryd, P.2    Sandstrom, R.3    Korner, U.4    Lundholm, K.5
  • 244
    • 0032969834 scopus 로고    scopus 로고
    • Intralipid infusion combined with propranolol administration has favorable metabolic effects in elderly malnourished cancer patients
    • A. Gambardella R. Tortoriello L. Pesce M.R. Tagliamonte G. Paolisso M. Varricchio Intralipid infusion combined with propranolol administration has favorable metabolic effects in elderly malnourished cancer patients Metabolism 48 3 1999 291 297
    • (1999) Metabolism , vol.48 , Issue.3 , pp. 291-297
    • Gambardella, A.1    Tortoriello, R.2    Pesce, L.3    Tagliamonte, M.R.4    Paolisso, G.5    Varricchio, M.6
  • 245
    • 0036535303 scopus 로고    scopus 로고
    • Energy metabolism and expression of uncoupling proteins 1, 2, and 3 after 21 days of recovery from intracerebroventricular mouse leptin in rats
    • P.S. Gullicksen W.P. Flatt R.G. Dean D.L. Hartzell C.A. Baile Energy metabolism and expression of uncoupling proteins 1, 2, and 3 after 21 days of recovery from intracerebroventricular mouse leptin in rats Physiol Behav 75 4 2002 473 482
    • (2002) Physiol Behav , vol.75 , Issue.4 , pp. 473-482
    • Gullicksen, P.S.1    Flatt, W.P.2    Dean, R.G.3    Hartzell, D.L.4    Baile, C.A.5
  • 246
    • 0033802857 scopus 로고    scopus 로고
    • Leptin stimulates uncoupling protein-2 mRNA expression and Krebs cycle activity and inhibits lipid synthesis in isolated rat white adipocytes
    • R.B. Ceddia W.N. William Jr. F.B. Lima P. Flandin R. Curi J.P. Giacobino Leptin stimulates uncoupling protein-2 mRNA expression and Krebs cycle activity and inhibits lipid synthesis in isolated rat white adipocytes Eur J Biochem 267 19 2000 5952 5958
    • (2000) Eur J Biochem , vol.267 , Issue.19 , pp. 5952-5958
    • Ceddia, R.B.1    William, W.N.2    Lima, F.B.3    Flandin, P.4    Curi, R.5    Giacobino, J.P.6
  • 247
    • 0033867178 scopus 로고    scopus 로고
    • Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes
    • D.E. Moller Potential role of TNF-alpha in the pathogenesis of insulin resistance and type 2 diabetes Trends Endocrinol Metab 11 6 2000 212 217
    • (2000) Trends Endocrinol Metab , vol.11 , Issue.6 , pp. 212-217
    • Moller, D.E.1
  • 248
    • 0027230553 scopus 로고
    • Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • A.L. Moreira E.P. Sampaio A. Zmuidzinas P. Frindt K.A. Smith G. Kaplan Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation J Exp Med 177 6 1993 1675 1680
    • (1993) J Exp Med , vol.177 , Issue.6 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3    Frindt, P.4    Smith, K.A.5    Kaplan, G.6
  • 249
    • 0029800251 scopus 로고    scopus 로고
    • Effects of thalidomide on HIV-associated wasting syndrome: a randomized, double, blind, placebo-controlled clinical trial
    • G. Reyes-Teran J. Sierra-Madero V. Martinez del Cerro Effects of thalidomide on HIV-associated wasting syndrome: a randomized, double, blind, placebo-controlled clinical trial AIDS 10 1996 1501 1507
    • (1996) AIDS , vol.10 , pp. 1501-1507
    • Reyes-Teran, G.1    Sierra-Madero, J.2    Martinez del Cerro, V.3
  • 250
    • 0028089362 scopus 로고
    • Use of pentoxifylline therapy for patients with AIDS-related wasting: pilot study
    • D. Landman A. Sarai S.S. Sathe Use of pentoxifylline therapy for patients with AIDS-related wasting: pilot study Clin Infect Dis 18 1 1994 97 99
    • (1994) Clin Infect Dis , vol.18 , Issue.1 , pp. 97-99
    • Landman, D.1    Sarai, A.2    Sathe, S.S.3
  • 251
    • 0028361853 scopus 로고
    • Pentoxifylline aggravates impairment in tumor necrosis factor-alpha secretion and increases mycobacterial load in macrophages from AIDS patients with disseminated Mycobacterium avium-intracellulare complex infection
    • S.S. Sathe A. Sarai D. Tsigler D. Nedunchezian Pentoxifylline aggravates impairment in tumor necrosis factor-alpha secretion and increases mycobacterial load in macrophages from AIDS patients with disseminated Mycobacterium avium-intracellulare complex infection J Infect Dis 170 2 1994 484 487
    • (1994) J Infect Dis , vol.170 , Issue.2 , pp. 484-487
    • Sathe, S.S.1    Sarai, A.2    Tsigler, D.3    Nedunchezian, D.4
  • 252
    • 0032867672 scopus 로고    scopus 로고
    • Use of recombinant human soluble TNF receptor in anorectic tumor-bearing rats
    • G.F. Torelli M.M. Meguid L.L. Moldawer Use of recombinant human soluble TNF receptor in anorectic tumor-bearing rats Am J Physiol 277 3 Pt 2 1999 R850 R855
    • (1999) Am J Physiol , vol.277 , Issue.3 Pt 2 , pp. R850-R855
    • Torelli, G.F.1    Meguid, M.M.2    Moldawer, L.L.3
  • 253
    • 34548732637 scopus 로고    scopus 로고
    • A placebo-controlled double blind trial of etanercept for the cancer anorexia/weight loss syndrome: results from N00C1 from the North Central Cancer Treatment Group
    • A. Jatoi S.R. Dakhil P.L. Nguyen A placebo-controlled double blind trial of etanercept for the cancer anorexia/weight loss syndrome: results from N00C1 from the North Central Cancer Treatment Group Cancer 110 6 2007 1396 1403
    • (2007) Cancer , vol.110 , Issue.6 , pp. 1396-1403
    • Jatoi, A.1    Dakhil, S.R.2    Nguyen, P.L.3
  • 254
    • 33845491244 scopus 로고    scopus 로고
    • Randomized phase 2 trial of anti-tumor necrosis factor therapy for cachexia in patients with early rheumatoid arthritis
    • S.M. Marcora K.R. Chester G. Mittal A.B. Lemmey P.J. Maddison Randomized phase 2 trial of anti-tumor necrosis factor therapy for cachexia in patients with early rheumatoid arthritis Am J Clin Nutr 84 6 2006 1463 1472
    • (2006) Am J Clin Nutr , vol.84 , Issue.6 , pp. 1463-1472
    • Marcora, S.M.1    Chester, K.R.2    Mittal, G.3    Lemmey, A.B.4    Maddison, P.J.5
  • 255
    • 0026047605 scopus 로고
    • Increased concentrations of tumour necrosis factor in ”cachectic” patients with severe chronic heart failure
    • J. McMurray I. Abdullah H.J. Dargie D. Shapiro Increased concentrations of tumour necrosis factor in ”cachectic” patients with severe chronic heart failure Br Heart J 66 5 1991 356 358
    • (1991) Br Heart J , vol.66 , Issue.5 , pp. 356-358
    • McMurray, J.1    Abdullah, I.2    Dargie, H.J.3    Shapiro, D.4
  • 256
    • 0037465808 scopus 로고    scopus 로고
    • Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study
    • R.S. Vasan L.M. Sullivan R. Roubenoff Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart Study Circulation 107 11 2003 1486 1491
    • (2003) Circulation , vol.107 , Issue.11 , pp. 1486-1491
    • Vasan, R.S.1    Sullivan, L.M.2    Roubenoff, R.3
  • 257
    • 0035555054 scopus 로고    scopus 로고
    • High tumour necrosis factor-alpha levels are associated with exercise intolerance and neurohormonal activation in chronic heart failure patients
    • M. Cicoira A.P. Bolger W. Doehner High tumour necrosis factor-alpha levels are associated with exercise intolerance and neurohormonal activation in chronic heart failure patients Cytokine 15 2 2001 80 86
    • (2001) Cytokine , vol.15 , Issue.2 , pp. 80-86
    • Cicoira, M.1    Bolger, A.P.2    Doehner, W.3
  • 258
    • 0033406821 scopus 로고    scopus 로고
    • Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure
    • L. Gullestad P. Aukrust T. Ueland Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure J Am Coll Cardiol 34 7 1999 2061 2067
    • (1999) J Am Coll Cardiol , vol.34 , Issue.7 , pp. 2061-2067
    • Gullestad, L.1    Aukrust, P.2    Ueland, T.3
  • 259
    • 11144355760 scopus 로고    scopus 로고
    • Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL)
    • D.L. Mann J.J. McMurray M. Packer Targeted anticytokine therapy in patients with chronic heart failure: results of the Randomized Etanercept Worldwide Evaluation (RENEWAL) Circulation 109 13 2004 1594 1602
    • (2004) Circulation , vol.109 , Issue.13 , pp. 1594-1602
    • Mann, D.L.1    McMurray, J.J.2    Packer, M.3
  • 260
    • 0036888364 scopus 로고    scopus 로고
    • How to RECOVER from RENAISSANCE?: The significance of the results of RECOVER, RENAISSANCE, RENEWAL and ATTACH
    • S.D. Anker A.J. Coats How to RECOVER from RENAISSANCE? The significance of the results of RECOVER, RENAISSANCE, RENEWAL and ATTACH Int J Cardiol 86 2-3 2002 123 130
    • (2002) Int J Cardiol , vol.86 , Issue.2-3 , pp. 123-130
    • Anker, S.D.1    Coats, A.J.2
  • 262
    • 0031004362 scopus 로고    scopus 로고
    • Proinflammatory cytokines, nutritional support, and the cachexia syndrome: interactions and therapeutic options
    • L.L. Moldawer E.M. Copeland 3rd Proinflammatory cytokines, nutritional support, and the cachexia syndrome: interactions and therapeutic options Cancer 79 9 1997 1828 1839
    • (1997) Cancer , vol.79 , Issue.9 , pp. 1828-1839
    • Moldawer, L.L.1    Copeland, E.M.2
  • 263
    • 0028670612 scopus 로고
    • Tumor necrosis factor and cachexia: a current perspective
    • N.J. Espat E.M. Copeland L.L. Moldawer Tumor necrosis factor and cachexia: a current perspective Surg Oncol 3 5 1994 255 262
    • (1994) Surg Oncol , vol.3 , Issue.5 , pp. 255-262
    • Espat, N.J.1    Copeland, E.M.2    Moldawer, L.L.3
  • 264
    • 0029089803 scopus 로고
    • Increased resting energy expenditure and weight loss are related to a systemic inflammatory response in lung cancer patients
    • A.J. Staal-van den Brekel M.A. Dentener A.M. Schols W.A. Buurman E.F. Wouters Increased resting energy expenditure and weight loss are related to a systemic inflammatory response in lung cancer patients J Clin Oncol 13 10 1995 2600 2605
    • (1995) J Clin Oncol , vol.13 , Issue.10 , pp. 2600-2605
    • Staal-van den Brekel, A.J.1    Dentener, M.A.2    Schols, A.M.3    Buurman, W.A.4    Wouters, E.F.5
  • 265
    • 0026530464 scopus 로고
    • IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor
    • P. Ralph I. Nakoinz A. Sampson-Johannes IL-10, T lymphocyte inhibitor of human blood cell production of IL-1 and tumor necrosis factor J Immunol 148 3 1992 808 814
    • (1992) J Immunol , vol.148 , Issue.3 , pp. 808-814
    • Ralph, P.1    Nakoinz, I.2    Sampson-Johannes, A.3
  • 266
    • 0027517422 scopus 로고
    • Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes: Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide
    • M.A. Cassatella L. Meda S. Bonora M. Ceska G. Constantin Interleukin 10 (IL-10) inhibits the release of proinflammatory cytokines from human polymorphonuclear leukocytes Evidence for an autocrine role of tumor necrosis factor and IL-1 beta in mediating the production of IL-8 triggered by lipopolysaccharide J Exp Med 178 6 1993 2207 2211
    • (1993) J Exp Med , vol.178 , Issue.6 , pp. 2207-2211
    • Cassatella, M.A.1    Meda, L.2    Bonora, S.3    Ceska, M.4    Constantin, G.5
  • 267
    • 0026503448 scopus 로고
    • Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist
    • E. Vannier L.C. Miller C.A. Dinarello Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist Proc Natl Acad Sci U S A 89 9 1992 4076 4080
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.9 , pp. 4076-4080
    • Vannier, E.1    Miller, L.C.2    Dinarello, C.A.3
  • 268
    • 0027370379 scopus 로고
    • Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis
    • J.B. Allen H.L. Wong G.L. Costa M.J. Bienkowski S.M. Wahl Suppression of monocyte function and differential regulation of IL-1 and IL-1ra by IL-4 contribute to resolution of experimental arthritis J Immunol 151 8 1993 4344 4351
    • (1993) J Immunol , vol.151 , Issue.8 , pp. 4344-4351
    • Allen, J.B.1    Wong, H.L.2    Costa, G.L.3    Bienkowski, M.J.4    Wahl, S.M.5
  • 269
    • 0031771216 scopus 로고    scopus 로고
    • Cytokine-induced anorexia: Behavioral, cellular, and molecular mechanisms
    • C.R. Plata-Salaman Cytokine-induced anorexia Behavioral, cellular, and molecular mechanisms Ann N Y Acad Sci 856 1998 160 170
    • (1998) Ann N Y Acad Sci , vol.856 , pp. 160-170
    • Plata-Salaman, C.R.1
  • 270
    • 0033966866 scopus 로고    scopus 로고
    • Cytokine-cytokine interactions and the brain
    • N.P. Turrin C.R. Plata-Salaman Cytokine-cytokine interactions and the brain Brain Res Bull 51 1 2000 3 9
    • (2000) Brain Res Bull , vol.51 , Issue.1 , pp. 3-9
    • Turrin, N.P.1    Plata-Salaman, C.R.2
  • 271
    • 0031014962 scopus 로고    scopus 로고
    • Prevention of adenocarcinoma colon 26-induced cachexia by interleukin 10 gene transfer
    • F. Fujiki N. Mukaida K. Hirose Prevention of adenocarcinoma colon 26-induced cachexia by interleukin 10 gene transfer Cancer Res 57 1 1997 94 99
    • (1997) Cancer Res , vol.57 , Issue.1 , pp. 94-99
    • Fujiki, F.1    Mukaida, N.2    Hirose, K.3
  • 272
    • 0029980286 scopus 로고    scopus 로고
    • Viral IL-10 gene therapy inhibits TNF-alpha and IL-1 beta, not IL-6, in the newborn endotoxemic mouse
    • K.E. Drazan L. Wu D. Bullington A. Shaked Viral IL-10 gene therapy inhibits TNF-alpha and IL-1 beta, not IL-6, in the newborn endotoxemic mouse J Pediatr Surg 31 3 1996 411 414
    • (1996) J Pediatr Surg , vol.31 , Issue.3 , pp. 411-414
    • Drazan, K.E.1    Wu, L.2    Bullington, D.3    Shaked, A.4
  • 273
    • 0028360403 scopus 로고
    • Effect of prostaglandins and their precursors on the proliferation of human lymphocytes and their secretion of tumor necrosis factor and various interleukins
    • G.S. Kumar U.N. Das Effect of prostaglandins and their precursors on the proliferation of human lymphocytes and their secretion of tumor necrosis factor and various interleukins Prostaglandins Leukot Essent Fatty Acids 50 6 1994 331 334
    • (1994) Prostaglandins Leukot Essent Fatty Acids , vol.50 , Issue.6 , pp. 331-334
    • Kumar, G.S.1    Das, U.N.2
  • 275
    • 0030633512 scopus 로고    scopus 로고
    • TNF-alpha, IL-1 and IL-6 concentration in bronchoalveolar lavage fluid (BALF) of non-small cell lung cancer (NSCLC)
    • E. Chyczewska R.M. Mroz E. Kowal TNF-alpha, IL-1 and IL-6 concentration in bronchoalveolar lavage fluid (BALF) of non-small cell lung cancer (NSCLC) Rocz Akad Med Bialymst 42 Suppl 1 1997 123 135
    • (1997) Rocz Akad Med Bialymst , vol.42 , Issue.Suppl 1 , pp. 123-135
    • Chyczewska, E.1    Mroz, R.M.2    Kowal, E.3
  • 276
    • 34447300492 scopus 로고    scopus 로고
    • Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
    • N. Nishimoto J. Hashimoto N. Miyasaka Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab Ann Rheum Dis 66 9 2007 1162 1167
    • (2007) Ann Rheum Dis , vol.66 , Issue.9 , pp. 1162-1167
    • Nishimoto, N.1    Hashimoto, J.2    Miyasaka, N.3
  • 277
    • 33644622705 scopus 로고    scopus 로고
    • Overexpression of UCP3 in both murine and human myotubes is linked with the activation of proteolytic systems: a role in muscle wasting?
    • S. Busquets C. Garcia-Martinez M. Olivan E. Barreiro F.J. Lopez-Soriano J.M. Argiles Overexpression of UCP3 in both murine and human myotubes is linked with the activation of proteolytic systems: a role in muscle wasting? Biochim Biophys Acta 1760 2 2006 253 258
    • (2006) Biochim Biophys Acta , vol.1760 , Issue.2 , pp. 253-258
    • Busquets, S.1    Garcia-Martinez, C.2    Olivan, M.3    Barreiro, E.4    Lopez-Soriano, F.J.5    Argiles, J.M.6
  • 278
    • 33746629771 scopus 로고    scopus 로고
    • TNF-alpha mediated suppression of tissue type plasminogen activator expression in vascular endothelial cells is NF-kappaB- and p38 MAPK-dependent
    • E. Ulfhammer P. Larsson L. Karlsson TNF-alpha mediated suppression of tissue type plasminogen activator expression in vascular endothelial cells is NF-kappaB- and p38 MAPK-dependent J Thromb Haemost 4 8 2006 1781 1789
    • (2006) J Thromb Haemost , vol.4 , Issue.8 , pp. 1781-1789
    • Ulfhammer, E.1    Larsson, P.2    Karlsson, L.3
  • 279
    • 33745654304 scopus 로고    scopus 로고
    • The signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB pathways, and synergistic effect of several proinflammatory cytokines
    • H. Fujigaki K. Saito S. Fujigaki The signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 are not essential for the induction of indoleamine 2,3-dioxygenase by lipopolysaccharide: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB pathways, and synergistic effect of several proinflammatory cytokines J Biochem (Tokyo) 139 4 2006 655 662
    • (2006) J Biochem (Tokyo) , vol.139 , Issue.4 , pp. 655-662
    • Fujigaki, H.1    Saito, K.2    Fujigaki, S.3
  • 280
    • 12344289433 scopus 로고    scopus 로고
    • Diversity and similarity in signaling events leading to rapid Cox-2 induction by tumor necrosis factor-alpha and phorbol ester in human endothelial cells
    • S. Eligini S. Stella Barbieri V. Cavalca Diversity and similarity in signaling events leading to rapid Cox-2 induction by tumor necrosis factor-alpha and phorbol ester in human endothelial cells Cardiovasc Res 65 3 2005 683 693
    • (2005) Cardiovasc Res , vol.65 , Issue.3 , pp. 683-693
    • Eligini, S.1    Stella Barbieri, S.2    Cavalca, V.3
  • 281
    • 9444228220 scopus 로고    scopus 로고
    • Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease
    • E. Hollenbach M. Neumann M. Vieth A. Roessner P. Malfertheiner M. Naumann Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease Faseb J 18 13 2004 1550 1552
    • (2004) Faseb J , vol.18 , Issue.13 , pp. 1550-1552
    • Hollenbach, E.1    Neumann, M.2    Vieth, M.3    Roessner, A.4    Malfertheiner, P.5    Naumann, M.6
  • 282
    • 0037090078 scopus 로고    scopus 로고
    • Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia
    • J. Branger B. van den Blink S. Weijer Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia J Immunol 168 8 2002 4070 4077
    • (2002) J Immunol , vol.168 , Issue.8 , pp. 4070-4077
    • Branger, J.1    van den Blink, B.2    Weijer, S.3
  • 284
    • 28844509240 scopus 로고    scopus 로고
    • Myostatin: a modulator of skeletal-muscle stem cells
    • F.S. Walsh A.J. Celeste Myostatin: a modulator of skeletal-muscle stem cells Biochem Soc Trans 33 Pt 6 2005 1513 1517
    • (2005) Biochem Soc Trans , vol.33 , Issue.Pt 6 , pp. 1513-1517
    • Walsh, F.S.1    Celeste, A.J.2
  • 285
    • 29144466479 scopus 로고    scopus 로고
    • Regulation of muscle growth by multiple ligands signaling through activin type II receptors
    • S.J. Lee L.A. Reed M.V. Davies Regulation of muscle growth by multiple ligands signaling through activin type II receptors Proc Natl Acad Sci U S A 102 50 2005 18117 18122
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.50 , pp. 18117-18122
    • Lee, S.J.1    Reed, L.A.2    Davies, M.V.3
  • 286
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • S.J. Lee Regulation of muscle mass by myostatin Annu Rev Cell Dev Biol 20 2004 61 86
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 287
    • 0037165983 scopus 로고    scopus 로고
    • Induction of cachexia in mice by systemically administered myostatin
    • T.A. Zimmers M.V. Davies L.G. Koniaris Induction of cachexia in mice by systemically administered myostatin Science 296 5572 2002 1486 1488
    • (2002) Science , vol.296 , Issue.5572 , pp. 1486-1488
    • Zimmers, T.A.1    Davies, M.V.2    Koniaris, L.G.3
  • 288
    • 0037462964 scopus 로고    scopus 로고
    • Inhibition of myostatin in adult mice increases skeletal muscle mass and strength
    • L.A. Whittemore K. Song X. Li Inhibition of myostatin in adult mice increases skeletal muscle mass and strength Biochem Biophys Res Commun 300 4 2003 965 971
    • (2003) Biochem Biophys Res Commun , vol.300 , Issue.4 , pp. 965-971
    • Whittemore, L.A.1    Song, K.2    Li, X.3
  • 289
    • 34447550642 scopus 로고    scopus 로고
    • Activin-type II receptor B (ACVR2B) and follistatin haplotype associations with muscle mass and strength in humans
    • S. Walsh E.J. Metter L. Ferrucci S.M. Roth Activin-type II receptor B (ACVR2B) and follistatin haplotype associations with muscle mass and strength in humans J Appl Physiol 102 6 2007 2142 2148
    • (2007) J Appl Physiol , vol.102 , Issue.6 , pp. 2142-2148
    • Walsh, S.1    Metter, E.J.2    Ferrucci, L.3    Roth, S.M.4
  • 290
    • 0037440415 scopus 로고    scopus 로고
    • Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide
    • F. Facchinetti E. Del Giudice S. Furegato M. Passarotto A. Leon Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide Glia 41 2 2003 161 168
    • (2003) Glia , vol.41 , Issue.2 , pp. 161-168
    • Facchinetti, F.1    Del Giudice, E.2    Furegato, S.3    Passarotto, M.4    Leon, A.5
  • 291
    • 34250645732 scopus 로고    scopus 로고
    • Endocannabinoid system in cancer cachexia
    • D. Osei-Hyiaman Endocannabinoid system in cancer cachexia Curr Opin Clin Nutr Metab Care 10 4 2007 443 448
    • (2007) Curr Opin Clin Nutr Metab Care , vol.10 , Issue.4 , pp. 443-448
    • Osei-Hyiaman, D.1
  • 292
    • 33744748305 scopus 로고    scopus 로고
    • A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress
    • G. Mantovani A. Maccio C. Madeddu A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress Cancer Epidemiol Biomarkers Prev 15 5 2006 1030 1034
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , Issue.5 , pp. 1030-1034
    • Mantovani, G.1    Maccio, A.2    Madeddu, C.3
  • 293
    • 34347390805 scopus 로고    scopus 로고
    • Pharmacological treatment of geriatric cachexia: evidence and safety in perspective
    • S.S. Yeh S. Lovitt M.W. Schuster Pharmacological treatment of geriatric cachexia: evidence and safety in perspective J Am Med Dir Assoc 8 6 2007 363 377
    • (2007) J Am Med Dir Assoc , vol.8 , Issue.6 , pp. 363-377
    • Yeh, S.S.1    Lovitt, S.2    Schuster, M.W.3
  • 294
    • 34250888937 scopus 로고    scopus 로고
    • Ghrelin treatment causes increased food intake and retention of lean body mass in a rat model of cancer cachexia
    • M.D. DeBoer X.X. Zhu P. Levasseur Ghrelin treatment causes increased food intake and retention of lean body mass in a rat model of cancer cachexia Endocrinology 148 6 2007 3004 3012
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 3004-3012
    • DeBoer, M.D.1    Zhu, X.X.2    Levasseur, P.3
  • 295
    • 1542343913 scopus 로고    scopus 로고
    • Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ
    • A. Inui A. Asakawa C.Y. Bowers Ghrelin, appetite, and gastric motility: the emerging role of the stomach as an endocrine organ Faseb J 18 3 2004 439 456
    • (2004) Faseb J , vol.18 , Issue.3 , pp. 439-456
    • Inui, A.1    Asakawa, A.2    Bowers, C.Y.3
  • 296
    • 33747153896 scopus 로고    scopus 로고
    • Ghrelin-neuropeptide Y axis in the control of feeding and gastrointestinal motility
    • A. Inui Ghrelin-neuropeptide Y axis in the control of feeding and gastrointestinal motility [in Japanese] Nippon Yakurigaku Zasshi 127 2 2006 83 87
    • (2006) Nippon Yakurigaku Zasshi , vol.127 , Issue.2 , pp. 83-87
    • Inui, A.1
  • 297
    • 0141784841 scopus 로고    scopus 로고
    • Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis
    • P. Villa P. Bigini T. Mennini Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis J Exp Med 198 6 2003 971 975
    • (2003) J Exp Med , vol.198 , Issue.6 , pp. 971-975
    • Villa, P.1    Bigini, P.2    Mennini, T.3
  • 298
    • 1642365861 scopus 로고    scopus 로고
    • Erythropoietin as a tissue-protective cytokine in brain injury: what do we know and where do we go?
    • G. Grasso A. Sfacteria A. Cerami M. Brines Erythropoietin as a tissue-protective cytokine in brain injury: what do we know and where do we go? Neuroscientist 10 2 2004 93 98
    • (2004) Neuroscientist , vol.10 , Issue.2 , pp. 93-98
    • Grasso, G.1    Sfacteria, A.2    Cerami, A.3    Brines, M.4
  • 299
    • 33746137372 scopus 로고    scopus 로고
    • Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise
    • M. Brines A. Cerami Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise Kidney Int 70 2 2006 246 250
    • (2006) Kidney Int , vol.70 , Issue.2 , pp. 246-250
    • Brines, M.1    Cerami, A.2
  • 300
    • 33847203208 scopus 로고    scopus 로고
    • Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives
    • P. Villa J. van Beek A.K. Larsen Reduced functional deficits, neuroinflammation, and secondary tissue damage after treatment of stroke by nonerythropoietic erythropoietin derivatives J Cereb Blood Flow Metab 27 3 2007 552 563
    • (2007) J Cereb Blood Flow Metab , vol.27 , Issue.3 , pp. 552-563
    • Villa, P.1    van Beek, J.2    Larsen, A.K.3
  • 301
    • 31944441026 scopus 로고    scopus 로고
    • Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy
    • G. Gramignano M.R. Lusso C. Madeddu Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy Nutrition 22 2 2006 136 145
    • (2006) Nutrition , vol.22 , Issue.2 , pp. 136-145
    • Gramignano, G.1    Lusso, M.R.2    Madeddu, C.3
  • 302
    • 33645274937 scopus 로고    scopus 로고
    • Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging
    • S. Bhasin O.M. Calof T.W. Storer Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging Nat Clin Pract Endocrinol Metab 2 3 2006 146 159
    • (2006) Nat Clin Pract Endocrinol Metab , vol.2 , Issue.3 , pp. 146-159
    • Bhasin, S.1    Calof, O.M.2    Storer, T.W.3
  • 303
    • 4544351073 scopus 로고    scopus 로고
    • Myostatin: a therapeutic target for skeletal muscle wasting
    • S.M. Roth S. Walsh Myostatin: a therapeutic target for skeletal muscle wasting Curr Opin Clin Nutr Metab Care 7 3 2004 259 263
    • (2004) Curr Opin Clin Nutr Metab Care , vol.7 , Issue.3 , pp. 259-263
    • Roth, S.M.1    Walsh, S.2
  • 304
    • 34948886115 scopus 로고    scopus 로고
    • Targets of anticytokine therapy and the risk of infections in humans and mice
    • E. van de Vosse M.A. van Agtmael Targets of anticytokine therapy and the risk of infections in humans and mice Curr Opin Rheumatol 19 6 2007 626 635
    • (2007) Curr Opin Rheumatol , vol.19 , Issue.6 , pp. 626-635
    • van de Vosse, E.1    van Agtmael, M.A.2
  • 305
    • 23044451227 scopus 로고    scopus 로고
    • Human immunodeficiencies that predispose to intracellular bacterial infections
    • R. Doffinger S. Patel D.S. Kumararatne Human immunodeficiencies that predispose to intracellular bacterial infections Curr Opin Rheumatol 17 4 2005 440 446
    • (2005) Curr Opin Rheumatol , vol.17 , Issue.4 , pp. 440-446
    • Doffinger, R.1    Patel, S.2    Kumararatne, D.S.3
  • 306
    • 14844334633 scopus 로고    scopus 로고
    • New concepts in anti-tumor necrosis factor therapy for inflammatory bowel disease
    • W.J. Sandborn New concepts in anti-tumor necrosis factor therapy for inflammatory bowel disease Rev Gastroenterol Disord 5 1 2005 10 18
    • (2005) Rev Gastroenterol Disord , vol.5 , Issue.1 , pp. 10-18
    • Sandborn, W.J.1
  • 307
    • 34248146920 scopus 로고    scopus 로고
    • Drug-induced systemic lupus erythematosus: reports to The Netherlands Pharmacovigilance Centre Lareb
    • A.W. van Rijthoven J.A. van Roon Drug-induced systemic lupus erythematosus: reports to The Netherlands Pharmacovigilance Centre Lareb [in Dutch] Ned Tijdschr Geneeskd 151 14 2007 839 author reply
    • (2007) Ned Tijdschr Geneeskd , vol.151 , Issue.14 , pp. 839
    • van Rijthoven, A.W.1    van Roon, J.A.2
  • 308
    • 34047260574 scopus 로고    scopus 로고
    • Drug-induced lupus erythematosus in a patient treated with adalumimab
    • A.P. Spillane Y. Xia P.J. Sniezek Drug-induced lupus erythematosus in a patient treated with adalumimab J Am Acad Dermatol 56 5 Suppl 2007 S114 S116
    • (2007) J Am Acad Dermatol , vol.56 , Issue.5 Suppl , pp. S114-S116
    • Spillane, A.P.1    Xia, Y.2    Sniezek, P.J.3
  • 309
    • 34250343172 scopus 로고    scopus 로고
    • Lessons for lupus from tumour necrosis factor blockade
    • M. De Bandt Lessons for lupus from tumour necrosis factor blockade Lupus 15 11 2006 762 767
    • (2006) Lupus , vol.15 , Issue.11 , pp. 762-767
    • De Bandt, M.1
  • 310
    • 33748333248 scopus 로고    scopus 로고
    • Anti-TNF-alpha antibody therapies in autoimmune diseases
    • K. Chatzantoni A. Mouzaki Anti-TNF-alpha antibody therapies in autoimmune diseases Curr Top Med Chem 6 16 2006 1707 1714
    • (2006) Curr Top Med Chem , vol.6 , Issue.16 , pp. 1707-1714
    • Chatzantoni, K.1    Mouzaki, A.2
  • 312
    • 33846201713 scopus 로고    scopus 로고
    • Neurological complications of infliximab
    • M.G. Tektonidou Neurological complications of infliximab J Rheumatol 34 1 2007 237 author reply -8
    • (2007) J Rheumatol , vol.34 , Issue.1 , pp. 237
    • Tektonidou, M.G.1
  • 313
    • 39749167232 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha antagonists and neuropathy
    • J.P. Stubgen Tumor necrosis factor-alpha antagonists and neuropathy Muscle Nerve 37 3 2007 281 292
    • (2007) Muscle Nerve , vol.37 , Issue.3 , pp. 281-292
    • Stubgen, J.P.1
  • 314
    • 34548149410 scopus 로고    scopus 로고
    • Optic neuritis occurring with anti-tumour necrosis factor alpha therapy
    • I. Simsek H. Erdem S. Pay G. Sobaci A. Dinc Optic neuritis occurring with anti-tumour necrosis factor alpha therapy Ann Rheum Dis 66 9 2007 1255 1258
    • (2007) Ann Rheum Dis , vol.66 , Issue.9 , pp. 1255-1258
    • Simsek, I.1    Erdem, H.2    Pay, S.3    Sobaci, G.4    Dinc, A.5
  • 315
    • 37249063841 scopus 로고    scopus 로고
    • TNFalpha blockade in human diseases: An overview of efficacy and safety
    • J. Lin D. Ziring S. Desai TNFalpha blockade in human diseases: An overview of efficacy and safety Clin Immunol 126 1 2008 13 30 Jan
    • (2008) Clin Immunol , vol.126 , Issue.1 , pp. 13-30
    • Lin, J.1    Ziring, D.2    Desai, S.3
  • 316
    • 34347356379 scopus 로고    scopus 로고
    • Anti-TNFalpha treatment and reactivation of latent tuberculosis
    • O.M. Jolobe Anti-TNFalpha treatment and reactivation of latent tuberculosis Lancet 370 9581 2007 27 28
    • (2007) Lancet , vol.370 , Issue.9581 , pp. 27-28
    • Jolobe, O.M.1
  • 317
    • 34447118413 scopus 로고    scopus 로고
    • Pulmonary Mycobacterium szulgai infection and treatment in a patient receiving anti-tumor necrosis factor therapy
    • J. van Ingen M. Boeree M. Janssen Pulmonary Mycobacterium szulgai infection and treatment in a patient receiving anti-tumor necrosis factor therapy Nat Clin Pract Rheumatol 3 7 2007 414 419
    • (2007) Nat Clin Pract Rheumatol , vol.3 , Issue.7 , pp. 414-419
    • van Ingen, J.1    Boeree, M.2    Janssen, M.3
  • 318
    • 0035846326 scopus 로고    scopus 로고
    • Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
    • J. Keane S. Gershon R.P. Wise Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent N Engl J Med 345 15 2001 1098 1104
    • (2001) N Engl J Med , vol.345 , Issue.15 , pp. 1098-1104
    • Keane, J.1    Gershon, S.2    Wise, R.P.3
  • 319
    • 0037666987 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor alpha therapy in fifteen patients with AA amyloidosis secondary to inflammatory arthritides: a followup report of tolerability and efficacy
    • J.E. Gottenberg F. Merle-Vincent F. Bentaberry Anti-tumor necrosis factor alpha therapy in fifteen patients with AA amyloidosis secondary to inflammatory arthritides: a followup report of tolerability and efficacy Arthritis Rheum 48 7 2003 2019 2024
    • (2003) Arthritis Rheum , vol.48 , Issue.7 , pp. 2019-2024
    • Gottenberg, J.E.1    Merle-Vincent, F.2    Bentaberry, F.3
  • 320
    • 0036900501 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist therapy and lymphoma development: twenty-six cases reported to the Food and Drug Administration
    • S.L. Brown M.H. Greene S.K. Gershon E.T. Edwards M.M. Braun Tumor necrosis factor antagonist therapy and lymphoma development: twenty-six cases reported to the Food and Drug Administration Arthritis Rheum 46 12 2002 3151 3158
    • (2002) Arthritis Rheum , vol.46 , Issue.12 , pp. 3151-3158
    • Brown, S.L.1    Greene, M.H.2    Gershon, S.K.3    Edwards, E.T.4    Braun, M.M.5
  • 322
    • 0035033807 scopus 로고    scopus 로고
    • Etanercept combined with conventional treatment in Wegener's granulomatosis: a six-month open-label trial to evaluate safety
    • J.H. Stone M.L. Uhlfelder D.B. Hellmann S. Crook N.M. Bedocs G.S. Hoffman Etanercept combined with conventional treatment in Wegener's granulomatosis: a six-month open-label trial to evaluate safety Arthritis Rheum 44 5 2001 1149 1154
    • (2001) Arthritis Rheum , vol.44 , Issue.5 , pp. 1149-1154
    • Stone, J.H.1    Uhlfelder, M.L.2    Hellmann, D.B.3    Crook, S.4    Bedocs, N.M.5    Hoffman, G.S.6
  • 323
    • 33747175126 scopus 로고    scopus 로고
    • The clinical application of etanercept in Chinese patients with rheumatic diseases
    • C.T. Chou The clinical application of etanercept in Chinese patients with rheumatic diseases Mod Rheumatol 16 4 2006 206 213
    • (2006) Mod Rheumatol , vol.16 , Issue.4 , pp. 206-213
    • Chou, C.T.1
  • 324
    • 34249744516 scopus 로고    scopus 로고
    • Serious adverse events with infliximab: analysis of spontaneously reported adverse events
    • R.A. Hansen G. Gartlehner G.E. Powell R.S. Sandler Serious adverse events with infliximab: analysis of spontaneously reported adverse events Clin Gastroenterol Hepatol 5 6 2007 729 735
    • (2007) Clin Gastroenterol Hepatol , vol.5 , Issue.6 , pp. 729-735
    • Hansen, R.A.1    Gartlehner, G.2    Powell, G.E.3    Sandler, R.S.4
  • 325
    • 33644875213 scopus 로고    scopus 로고
    • TNF-alpha inhibitors and congestive heart failure
    • S.M. Behnam S.E. Behnam J.Y. Koo TNF-alpha inhibitors and congestive heart failure Skinmed 4 6 2005 363 368
    • (2005) Skinmed , vol.4 , Issue.6 , pp. 363-368
    • Behnam, S.M.1    Behnam, S.E.2    Koo, J.Y.3
  • 326
    • 33646696885 scopus 로고    scopus 로고
    • Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials
    • T. Bongartz A.J. Sutton M.J. Sweeting I. Buchan E.L. Matteson V. Montori Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials Jama 295 19 2006 2275 2285
    • (2006) Jama , vol.295 , Issue.19 , pp. 2275-2285
    • Bongartz, T.1    Sutton, A.J.2    Sweeting, M.J.3    Buchan, I.4    Matteson, E.L.5    Montori, V.6
  • 327
    • 33947417337 scopus 로고    scopus 로고
    • Cancer cachexia signaling pathways continue to emerge yet much still points to the proteasome
    • S. Acharyya D.C. Guttridge Cancer cachexia signaling pathways continue to emerge yet much still points to the proteasome Clin Cancer Res 13 5 2007 1356 1361
    • (2007) Clin Cancer Res , vol.13 , Issue.5 , pp. 1356-1361
    • Acharyya, S.1    Guttridge, D.C.2
  • 328
    • 34250218193 scopus 로고    scopus 로고
    • NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes
    • H. Wang E. Hertlein N. Bakkar NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes Mol Cell Biol 27 12 2007 4374 4387
    • (2007) Mol Cell Biol , vol.27 , Issue.12 , pp. 4374-4387
    • Wang, H.1    Hertlein, E.2    Bakkar, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.