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Volumn 48, Issue 9, 1999, Pages 1822-1829

Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressing leptin

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN; INSULIN; LEPTIN; LIPID;

EID: 0032848779     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.9.1822     Document Type: Article
Times cited : (178)

References (44)
  • 1
    • 0030297919 scopus 로고    scopus 로고
    • Adipogenesis and obesity: Rounding out the big picture
    • Spiegelman BM, Flier JS: Adipogenesis and obesity: rounding out the big picture. Cell 87:377-389, 1996
    • (1996) Cell , vol.87 , pp. 377-389
    • Spiegelman, B.M.1    Flier, J.S.2
  • 2
    • 0028947949 scopus 로고
    • The fourth musketeer from Alexandre Dumas to Claude Bernard
    • Reaven GM: The fourth musketeer from Alexandre Dumas to Claude Bernard. Diabetologia 38:3-13, 1995
    • (1995) Diabetologia , vol.38 , pp. 3-13
    • Reaven, G.M.1
  • 3
    • 0026635508 scopus 로고
    • Cellular and molecular aspects of adipose tissue development
    • Ailhaud G, Grimaldi P, Negrel R: Cellular and molecular aspects of adipose tissue development Annu Rev Nutr 12:207-233, 1992
    • (1992) Annu Rev Nutr , vol.12 , pp. 207-233
    • Ailhaud, G.1    Grimaldi, P.2    Negrel, R.3
  • 4
    • 0032558725 scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 395:763-770, 1968
    • (1968) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 9
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P: Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549, 1995
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 14
    • 0008466784 scopus 로고    scopus 로고
    • Intracerebroventricular administration of leptin markedly enhances insulin sensitivity and systemic glucose utilization in conscious rats
    • Shi ZQ, Nelson A, Whitcomb L, Wang J, Cohen AM: Intracerebroventricular administration of leptin markedly enhances insulin sensitivity and systemic glucose utilization in conscious rats. Metabolism 47:1274-1280, 1998
    • (1998) Metabolism , vol.47 , pp. 1274-1280
    • Shi, Z.Q.1    Nelson, A.2    Whitcomb, L.3    Wang, J.4    Cohen, A.M.5
  • 18
    • 0032913312 scopus 로고    scopus 로고
    • Leptin enhances glycogen storage in hepatocytes by inhibition of phosphorylase and exerts an additive effect with insulin
    • Aiston S, Agius L: Leptin enhances glycogen storage in hepatocytes by inhibition of phosphorylase and exerts an additive effect with insulin. Diabetes 48:15-20, 1999
    • (1999) Diabetes , vol.48 , pp. 15-20
    • Aiston, S.1    Agius, L.2
  • 19
    • 0030965884 scopus 로고    scopus 로고
    • Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion
    • Emilsson V, Liu Y-L, Cawthrone MA, Morton NM, Davenport M: Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion. Diabetes 46:313-316, 1997
    • (1997) Diabetes , vol.46 , pp. 313-316
    • Emilsson, V.1    Liu, Y.-L.2    Cawthrone, M.A.3    Morton, N.M.4    Davenport, M.5
  • 20
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
    • Frederich RC, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier JS: Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nature Med 1:1311-1314, 1995
    • (1995) Nature Med , vol.1 , pp. 1311-1314
    • Frederich, R.C.1    Hamann, A.2    Anderson, S.3    Lollmann, B.4    Lowell, B.B.5    Flier, J.S.6
  • 26
    • 0028205302 scopus 로고
    • Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene
    • Ogawa Y, Itoh H, Tamura N, Suga S, Yoshimasa T, Uehira M, Matsuda S, Shiono S, Nishimoto H, Nakao K: Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene. J Clin Invest 93:1911-1921, 1994
    • (1994) J Clin Invest , vol.93 , pp. 1911-1921
    • Ogawa, Y.1    Itoh, H.2    Tamura, N.3    Suga, S.4    Yoshimasa, T.5    Uehira, M.6    Matsuda, S.7    Shiono, S.8    Nishimoto, H.9    Nakao, K.10
  • 28
    • 0030961962 scopus 로고    scopus 로고
    • Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and β cell glucokinase genes: Genetic reconstitution of diabetes as a polygenic disease
    • Terauchi Y, Iwamoto K, Tamemoto H, Komeda K, Ishii C, Kanazawa Y, Asanuma N, Aizawa T, Akanuma Y, Yasuda K, Kodama T, Tobe K, Yazaki Y, Kadowaki T: Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and β cell glucokinase genes: genetic reconstitution of diabetes as a polygenic disease. J Clin Invest 99:861-866, 1997
    • (1997) J Clin Invest , vol.99 , pp. 861-866
    • Terauchi, Y.1    Iwamoto, K.2    Tamemoto, H.3    Komeda, K.4    Ishii, C.5    Kanazawa, Y.6    Asanuma, N.7    Aizawa, T.8    Akanuma, Y.9    Yasuda, K.10    Kodama, T.11    Tobe, K.12    Yazaki, Y.13    Kadowaki, T.14
  • 29
    • 15444341547 scopus 로고    scopus 로고
    • Differential activation of mitogen-activated protein kinase by insulin and epidermal growth factor in 3T3-L1 adipocytes: A possible involvement of PI3-kinase in the activation of the MAP kinase by insulin
    • Suga J, Yoshimasa Y, Yamada K, Yamamoto Y, Inoue G, Okamoto M, Hayashi T, Shigemoto M, Kosaki A, Kuzuya H, Nakao K: Differential activation of mitogen-activated protein kinase by insulin and epidermal growth factor in 3T3-L1 adipocytes: a possible involvement of PI3-kinase in the activation of the MAP kinase by insulin. Diabetes 46:735-741, 1997
    • (1997) Diabetes , vol.46 , pp. 735-741
    • Suga, J.1    Yoshimasa, Y.2    Yamada, K.3    Yamamoto, Y.4    Inoue, G.5    Okamoto, M.6    Hayashi, T.7    Shigemoto, M.8    Kosaki, A.9    Kuzuya, H.10    Nakao, K.11
  • 30
    • 0027484001 scopus 로고    scopus 로고
    • Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-dependent diabetes mellitus
    • Folli F, Saad MJA, Backer JM, Kahn CR: Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-dependent diabetes mellitus. J Clin Invest 92:1787-1794, 1997
    • (1997) J Clin Invest , vol.92 , pp. 1787-1794
    • Folli, F.1    Saad, M.J.A.2    Backer, J.M.3    Kahn, C.R.4
  • 31
    • 0032578453 scopus 로고    scopus 로고
    • Abnormal regulation of the leptin gene in the pathogenesis of obesity
    • Ioffe E, Moon B, Connolly E, Friedman JM: Abnormal regulation of the leptin gene in the pathogenesis of obesity. Proc Natl Acad U S A 95: 11852-11857, 1998
    • (1998) Proc Natl Acad U S A , vol.95 , pp. 11852-11857
    • Ioffe, E.1    Moon, B.2    Connolly, E.3    Friedman, J.M.4
  • 32
    • 0030867806 scopus 로고    scopus 로고
    • Genetics of human obesity: Research directions
    • Bray G, Bouchard C: Genetics of human obesity: research directions. FASEB J 11:937-945, 1997
    • (1997) FASEB J , vol.11 , pp. 937-945
    • Bray, G.1    Bouchard, C.2
  • 35
    • 0032532152 scopus 로고    scopus 로고
    • Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: Model for congenital generalized lipodystrophy
    • Shimomura I, Hammer RE, Richardson JA, Ikemoto S, Bashmakov Y, Goldstein JL, Brown MS: Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. Genes Dev 12:3182-3194, 1998
    • (1998) Genes Dev , vol.12 , pp. 3182-3194
    • Shimomura, I.1    Hammer, R.E.2    Richardson, J.A.3    Ikemoto, S.4    Bashmakov, Y.5    Goldstein, J.L.6    Brown, M.S.7
  • 36
    • 0026531633 scopus 로고
    • Glucose metabolism and thermogenesis during glucose and insulin infusion in severely underweight patients
    • Gallen IW, MacDonald IA, Allison SP: Glucose metabolism and thermogenesis during glucose and insulin infusion in severely underweight patients. J Parenter Enteral Nutr 16:5-10, 1992
    • (1992) J Parenter Enteral Nutr , vol.16 , pp. 5-10
    • Gallen, I.W.1    MacDonald, I.A.2    Allison, S.P.3
  • 37
    • 0028587742 scopus 로고
    • Tumor necrosis factor α: A key component of the obesity-diabetes link
    • Hotamisligil G, Spiegelman BM: Tumor necrosis factor α: a key component of the obesity-diabetes link. Diabetes 43:1271-1278, 1994
    • (1994) Diabetes , vol.43 , pp. 1271-1278
    • Hotamisligil, G.1    Spiegelman, B.M.2
  • 38
    • 0002016109 scopus 로고
    • Syndrome of extreme insulin resistance
    • Kahn CR, Weir GC, Eds. Philadelphia, Lea & Febiger
    • Goldstein BJ: Syndrome of extreme insulin resistance. In Joslin's Diabetes Mellitus. 13th ed. Kahn CR, Weir GC, Eds. Philadelphia, Lea & Febiger, 1994, p. 282-299
    • (1994) Joslin's Diabetes Mellitus. 13th Ed. , pp. 282-299
    • Goldstein, B.J.1
  • 41
    • 0029962467 scopus 로고    scopus 로고
    • Correction of obesity and diabetes in genetically obese mice by leptin gene therapy
    • Muzzin P, Eisensmith RC, Copeland KC, Woo SLC: Correction of obesity and diabetes in genetically obese mice by leptin gene therapy. Proc Natl Acad Sci U S A 93:14804-14808, 1996
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14804-14808
    • Muzzin, P.1    Eisensmith, R.C.2    Copeland, K.C.3    Woo, S.L.C.4
  • 42
    • 0030678119 scopus 로고    scopus 로고
    • Independent and additive effects of central POMC and leptin pathways on murine obesity
    • Boston BA, Blaydon KM, Varnerin J, Cone RD: Independent and additive effects of central POMC and leptin pathways on murine obesity. Science 278:1641-1644, 1997
    • (1997) Science , vol.278 , pp. 1641-1644
    • Boston, B.A.1    Blaydon, K.M.2    Varnerin, J.3    Cone, R.D.4
  • 44
    • 0029881125 scopus 로고    scopus 로고
    • Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
    • Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte R Jr. Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nature Med 2:589-593, 1996
    • (1996) Nature Med , vol.2 , pp. 589-593
    • Schwartz, M.W.1    Peskind, E.2    Raskind, M.3    Boyko, E.J.4    Porte R., Jr.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.