-
1
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
2
-
-
13344295079
-
Serum immunoreactive-leptin concentrations in normal-weight and obese humans
-
Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL 1996 Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295
-
(1996)
N Engl J Med
, vol.334
, pp. 292-295
-
-
Considine, R.V.1
Sinha, M.K.2
Heiman, M.L.3
Kriauciunas, A.4
Stephens, T.W.5
Nyce, M.R.6
Ohannesian, J.P.7
Marco, C.C.8
McKee, L.J.9
Bauer, T.L.10
-
3
-
-
0029881125
-
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
-
Schwartz MW, Peskind E, Raskind M, Boyko EJ, Porte Jr D 1996 Cerebrospinal fluid leptin levels: relationship to plasma levels and to adiposity in humans. Nat Med 2:589-593
-
(1996)
Nat Med
, vol.2
, pp. 589-593
-
-
Schwartz, M.W.1
Peskind, E.2
Raskind, M.3
Boyko, E.J.4
Porte Jr, D.5
-
4
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S 1995 Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat Med 1:1155-1161
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
Fei, H.7
Kim, S.8
Lallone, R.9
Ranganathan, S.10
-
5
-
-
0030737953
-
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
-
Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA, Friedman JM 1997 Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc Natl Acad Sci USA 94:8878-8883
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8878-8883
-
-
Halaas, J.L.1
Boozer, C.2
Blair-West, J.3
Fidahusein, N.4
Denton, D.A.5
Friedman, J.M.6
-
6
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM 1994 Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
7
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, O'Rahilly S 1997 Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387:903-908
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.R.12
Barnett, A.H.13
Prins, J.B.14
O'Rahilly, S.15
-
8
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
Schwartz MW, Seeley RJ, Campfield LA, Burn P, Baskin DG 1996 Identification of targets of leptin action in rat hypothalamus. J Clin Invest 98:1101-1106
-
(1996)
J Clin Invest
, vol.98
, pp. 1101-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
9
-
-
0029739826
-
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
-
Vaisse C, Halaas JL, Horvath CM, Darnell Jr JE, Stoffel M, Friedman JM 1996 Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet 14:95-97
-
(1996)
Nat Genet
, vol.14
, pp. 95-97
-
-
Vaisse, C.1
Halaas, J.L.2
Horvath, C.M.3
Darnell Jr, J.E.4
Stoffel, M.5
Friedman, J.M.6
-
10
-
-
0036321620
-
A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding
-
Zhao AZ, Huan JN, Gupta S, Pal R, Sahu A 2002 A phosphatidylinositol 3-kinase phosphodiesterase 3B-cyclic AMP pathway in hypothalamic action of leptin on feeding. Nat Neurosci 5:727-728
-
(2002)
Nat Neurosci
, vol.5
, pp. 727-728
-
-
Zhao, A.Z.1
Huan, J.N.2
Gupta, S.3
Pal, R.4
Sahu, A.5
-
11
-
-
0035950093
-
-
Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers Jr MG, Schwartz MW 2001 Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature 413:794-795
-
Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers Jr MG, Schwartz MW 2001 Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature 413:794-795
-
-
-
-
12
-
-
0035103849
-
Leptin mediates a proliferative response in human gastric mucosa cells with functional receptor
-
Schneider R, Bornstein SR, Chrousos GP, Boxberger S, Ehninger G, Breidert M 2001 Leptin mediates a proliferative response in human gastric mucosa cells with functional receptor. Horm Metab Res 33:1-6
-
(2001)
Horm Metab Res
, vol.33
, pp. 1-6
-
-
Schneider, R.1
Bornstein, S.R.2
Chrousos, G.P.3
Boxberger, S.4
Ehninger, G.5
Breidert, M.6
-
13
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley MA, Smart JL, Rubinstein M, Cerdan MG, Diano S, Horvath TL, Cone RD, Low MJ 2001 Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411:480-484
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
Cerdan, M.G.4
Diano, S.5
Horvath, T.L.6
Cone, R.D.7
Low, M.J.8
-
14
-
-
0029811162
-
Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus
-
Glaum SR, Hara M, Bindokas VP, Lee CC, Polonsky KS, Bell GI, Miller RJ 1996 Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus. Mol Pharmacol 50:230-235
-
(1996)
Mol Pharmacol
, vol.50
, pp. 230-235
-
-
Glaum, S.R.1
Hara, M.2
Bindokas, V.P.3
Lee, C.C.4
Polonsky, K.S.5
Bell, G.I.6
Miller, R.J.7
-
15
-
-
33745034786
-
Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: Implications for ingestive behaviour
-
Williams KW, Smith BN 2006 Rapid inhibition of neural excitability in the nucleus tractus solitarii by leptin: implications for ingestive behaviour. J Physiol 573:395-412
-
(2006)
J Physiol
, vol.573
, pp. 395-412
-
-
Williams, K.W.1
Smith, B.N.2
-
16
-
-
3843117676
-
Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin
-
Peters JH, Karpiel AB, Ritter RC, Simasko SM 2004 Cooperative activation of cultured vagal afferent neurons by leptin and cholecystokinin. Endocrinology 145:3652-3657
-
(2004)
Endocrinology
, vol.145
, pp. 3652-3657
-
-
Peters, J.H.1
Karpiel, A.B.2
Ritter, R.C.3
Simasko, S.M.4
-
17
-
-
33644850342
-
Leptin and CCK modulate complementary background conductances to depolarize cultured nodose neurons
-
Peters JH, Ritter RC, Simasko SM 2006 Leptin and CCK modulate complementary background conductances to depolarize cultured nodose neurons. Am J Physiol Cell Physiol 290:C427-C432
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Peters, J.H.1
Ritter, R.C.2
Simasko, S.M.3
-
19
-
-
0030824058
-
Two types of leptin-responsive gastric vagal afferent terminals: An in vitro single-unit study in rats
-
Wang YH, Tache Y, Sheibel AB, Go VL, Wei JY 1997 Two types of leptin-responsive gastric vagal afferent terminals: an in vitro single-unit study in rats. Am J Physiol 273:R833-R837
-
(1997)
Am J Physiol
, vol.273
-
-
Wang, Y.H.1
Tache, Y.2
Sheibel, A.B.3
Go, V.L.4
Wei, J.Y.5
-
20
-
-
12744273119
-
Luminal leptin induces rapid inhibition of active intestinal absorption of glucose mediated by sodium-glucose cotransporter 1
-
Ducroc R, Guilmeau S, Akasbi K, Devaud H, Buyse M, Bado A 2005 Luminal leptin induces rapid inhibition of active intestinal absorption of glucose mediated by sodium-glucose cotransporter 1. Diabetes 54:348-354
-
(2005)
Diabetes
, vol.54
, pp. 348-354
-
-
Ducroc, R.1
Guilmeau, S.2
Akasbi, K.3
Devaud, H.4
Buyse, M.5
Bado, A.6
-
21
-
-
33646107384
-
Large-scale preparation of biologically active mouse and rat leptins and their L39A/D40A/F41A muteins which act as potent antagonists
-
Salomon G, Niv-Spector L, Gussakovsky EE, Gertler A 2006 Large-scale preparation of biologically active mouse and rat leptins and their L39A/D40A/F41A muteins which act as potent antagonists. Protein Exp Purif 47:128-136
-
(2006)
Protein Exp Purif
, vol.47
, pp. 128-136
-
-
Salomon, G.1
Niv-Spector, L.2
Gussakovsky, E.E.3
Gertler, A.4
-
22
-
-
0035175995
-
Vagotomy decreases excitability in primary vagal afferent somata
-
Lancaster E, Oh EJ, Weinreich D 2001 Vagotomy decreases excitability in primary vagal afferent somata. J Neurophysiol 85:247-253
-
(2001)
J Neurophysiol
, vol.85
, pp. 247-253
-
-
Lancaster, E.1
Oh, E.J.2
Weinreich, D.3
-
23
-
-
25144489423
-
Identification of the hydrophobic strand in the A-B loop of leptin as major binding site. III. Implications for large-scale preparation of potent recombinant human and ovine leptin antagonists
-
Niv-Spector L, Gonen-Berger D, Gourdou I, Biener E, Gussakovsky EE, Benomar Y, Ramanujan KV, Taouis M, Herman B, Callebaut I, Djiane J, Gertler A 2005 Identification of the hydrophobic strand in the A-B loop of leptin as major binding site. III. Implications for large-scale preparation of potent recombinant human and ovine leptin antagonists. Biochem J 391:221-230
-
(2005)
Biochem J
, vol.391
, pp. 221-230
-
-
Niv-Spector, L.1
Gonen-Berger, D.2
Gourdou, I.3
Biener, E.4
Gussakovsky, E.E.5
Benomar, Y.6
Ramanujan, K.V.7
Taouis, M.8
Herman, B.9
Callebaut, I.10
Djiane, J.11
Gertler, A.12
-
24
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman JM, Halaas JL 1998 Leptin and the regulation of body weight in mammals. Nature 395:763-770
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
25
-
-
0035668492
-
Effects of chronic murine and human leptin infusion on plasma leptin and corticosterone levels and energy balance in lean Zucker rats
-
Al-Barazanji KA, Buckingham RE, Arch JR, Briscoe C, Jenkins O, Tadayyon M 2001 Effects of chronic murine and human leptin infusion on plasma leptin and corticosterone levels and energy balance in lean Zucker rats. Diabetes Obes Metab 3:435-442
-
(2001)
Diabetes Obes Metab
, vol.3
, pp. 435-442
-
-
Al-Barazanji, K.A.1
Buckingham, R.E.2
Arch, J.R.3
Briscoe, C.4
Jenkins, O.5
Tadayyon, M.6
-
26
-
-
33846446839
-
Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food following high-fat feeding are leptin dependent
-
Zhang J, Matheny MK, Tumer N, Mitchell MK, Scarpace PJ 2007 Leptin antagonist reveals that the normalization of caloric intake and the thermic effect of food following high-fat feeding are leptin dependent. Am J Physiol Regul Integr Comp Physiol 292:R868-R874
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.292
-
-
Zhang, J.1
Matheny, M.K.2
Tumer, N.3
Mitchell, M.K.4
Scarpace, P.J.5
-
27
-
-
30044434035
-
Intracellular signalling pathways activated by leptin
-
Fruhbeck G 2006 Intracellular signalling pathways activated by leptin. Biochem J 393:7-20
-
(2006)
Biochem J
, vol.393
, pp. 7-20
-
-
Fruhbeck, G.1
-
28
-
-
0034909166
-
Expression and regulation of leptin receptor proteins in afferent and efferent neurons of the vagus nerve
-
Buyse M, Ovesjo ML, Goiot H, Guilmeau S, Peranzi G, Moizo L, Walker F, Lewin MJ, Meister B, Bado A 2001 Expression and regulation of leptin receptor proteins in afferent and efferent neurons of the vagus nerve. Eur J Neurosci 14:64-72
-
(2001)
Eur J Neurosci
, vol.14
, pp. 64-72
-
-
Buyse, M.1
Ovesjo, M.L.2
Goiot, H.3
Guilmeau, S.4
Peranzi, G.5
Moizo, L.6
Walker, F.7
Lewin, M.J.8
Meister, B.9
Bado, A.10
-
29
-
-
0036499099
-
Leptin receptor expression in nodose ganglion cells projecting to the rat gastric fundus
-
Peiser C, Springer J, Groneberg DA, McGregor GP, Fischer A, Lang RE 2002 Leptin receptor expression in nodose ganglion cells projecting to the rat gastric fundus. Neurosci Lett 320:41-44
-
(2002)
Neurosci Lett
, vol.320
, pp. 41-44
-
-
Peiser, C.1
Springer, J.2
Groneberg, D.A.3
McGregor, G.P.4
Fischer, A.5
Lang, R.E.6
|