5-HT2C receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice

European Journal of Neuroscience

Volumn 25, Issue 10, 2007, Pages 3115-3124

  Somerville, Elizabeth M ^a   Horwood, Julia M ^a   Lee, Michelle D ^b   Kennett, Guy A ^c   Clifton, Peter G ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b SWANSEA UNIVERSITY   (United Kingdom)

^c Vernalis PLC   (United Kingdom)

Author keywords

CP 94,253; Satiety sequence; SB242084; Second order schedule; Serotonin; VER23779

Indexed keywords

2 [1 (CYCLOPROPYLMETHOXY)ETHYL] 5,5A,6,7,8,9 HEXAHYDRO 9 METHYLPYRIDO[3',2':4,5]PYRROLO[1,2A]PYRAZINE; 2,3,6,7 TETRAHYDRO 1' METHYL 5 [[2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL) 4 BIPHENYLYL]CARBONYL]SPIRO[FURO[2,3 F]INDOLE 3,4' PIPERIDINE]; 5 PROPOXY 3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; PROTEIN C FOS; SEROTONIN 1B ANTAGONIST; SEROTONIN 2A ANTAGONIST; SEROTONIN 2C AGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG; VER 23779;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; APPETITE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG DOSE ESCALATION; DRUG EFFECT; FEEDING BEHAVIOR; FOOD INTAKE; IMMUNOREACTIVITY; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PALATABILITY; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REINFORCEMENT; SATIETY; SEROTONINERGIC SYSTEM;

AMYGDALA; ANIMALS; APPETITE; BRAIN; FEEDING BEHAVIOR; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; NEURAL INHIBITION; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTOR, SEROTONIN, 5-HT2C; SATIETY RESPONSE; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SYNAPTIC TRANSMISSION; UP-REGULATION;

EID: 34249984987     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05567.x     Document Type: Article

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