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Decreased NPY innervation of the hypothalamic nuclei in rats with cancer anorexia
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Makarenko IG, Meguid MM, Gatto L, et al. Decreased NPY innervation of the hypothalamic nuclei in rats with cancer anorexia. Brain Res 2003; 961:100-108. Using the immunostaining technique, this elegant study demonstrates that, during tumor growth, the development of anorexia is associated with a significant reduction of neuropeptide Y innervation in the hypothalamus, particularly within the supraoptic nucleus, the parvocellular portion of the paraventricular nucleus, and to a lesser extent, the suprachiasmatic and arcuate nuclei.
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Effects of intra-VMN mianserin and IL-1ra on meal number in anorectic tumor-bearing rats
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Pro-inflammatory and anti-inflammatory cytokine mRNA induction in the periphery and brain following intraperitoneal administration of bacterial lipopolysaccharide
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Gram-negative and Gram-positive bacterial products induce differential cytokine profiles in the brain: Analysis using an integrative molecular-behavioral in vivo model
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HIV-1 gp120 modulates hypothalamic cytokine mRNAs in vivo: Implications to cytokine feedback systems
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