-
1
-
-
0027049534
-
Molecular characterization of the mouse agouti locus
-
Bultman SJ, Mirhaud EJ, Woychik RP: Molecular characterization of the mouse agouti locus. Cell 71:1195-1204, 1992
-
(1992)
Cell
, vol.71
, pp. 1195-1204
-
-
Bultman, S.J.1
Mirhaud, E.J.2
Woychik, R.P.3
-
2
-
-
0028112970
-
Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor
-
Lu D, Willard D, Patel IR, Kadwell S, Overton L, Kost T, Luther M, Chen W, Woychik RP, Wilkison WO, Cone RD: Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor. Nature 371:790-802, 1994
-
(1994)
Nature
, vol.371
, pp. 790-802
-
-
Lu, D.1
Willard, D.2
Patel, I.R.3
Kadwell, S.4
Overton, L.5
Kost, T.6
Luther, M.7
Chen, W.8
Woychik, R.P.9
Wilkison, W.O.10
Cone, R.D.11
-
3
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F: Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141, 1997
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
4
-
-
0030614331
-
Role of melanocurtinergic neurons in feeding and the agouti obesity syndrome
-
Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD: Role of melanocurtinergic neurons in feeding and the agouti obesity syndrome, Nature 385:165-168, 1997
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
5
-
-
0029983180
-
Obese gene expression: Reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced,) and genetic (yellow agouti) obesity
-
Mizuno TM, Bergen H, Funabashi T, Kleopoulos SP, Zhong YG, Bauman WA, Mobbs CV: Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced,) and genetic (yellow agouti) obesity. Proc Natl Acad Sci USA 93: 3434-3438, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3434-3438
-
-
Mizuno, T.M.1
Bergen, H.2
Funabashi, T.3
Kleopoulos, S.P.4
Zhong, Y.G.5
Bauman, W.A.6
Mobbs, C.V.7
-
6
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Mattel M, Barone M, Leopold L, Friedman JM: Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432, 1994
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Mattel, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
7
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM: Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
8
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob micy
-
Schwartz MW, Baskin DG, Bukowski TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D Jr. Woods SC, Seeley W, Weigle DS: Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob micy. Diabetes 45:531-535, 1990
-
(1990)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
Kuijper, J.L.4
Foster, D.5
Lasser, G.6
Prunkard, D.E.7
Porte Jr., D.8
Woods, S.C.9
Seeley, W.10
Weigle, D.S.11
-
9
-
-
0025233474
-
HIP-70: A protein induced by estrogen in the brain and LH-RH in the pituitary
-
Mobbs CV, Fink G, Pfaff DW: HIP-70: a protein induced by estrogen in the brain and LH-RH in the pituitary. Science 247:1477-1479, 1990
-
(1990)
Science
, vol.247
, pp. 1477-1479
-
-
Mobbs, C.V.1
Fink, G.2
Pfaff, D.W.3
-
10
-
-
0030058547
-
Ventromedial hypothalamic lesions produced by gold thioglucose do not impair induction of fasting
-
Bergen HT, Mobbs CV: Ventromedial hypothalamic lesions produced by gold thioglucose do not impair induction of fasting. Brain Res 707:266-271, 1996
-
(1996)
Brain Res
, vol.707
, pp. 266-271
-
-
Bergen, H.T.1
Mobbs, C.V.2
-
11
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AK, Barnett AH, Prins JB, O'Rahilly S: Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 307:903-908, 1997
-
(1997)
Nature
, vol.307
, pp. 903-908
-
-
Montague, C.T.1
Farooqi, I.S.2
Whitehead, J.P.3
Soos, M.A.4
Rau, H.5
Wareham, N.J.6
Sewter, C.P.7
Digby, J.E.8
Mohammed, S.N.9
Hurst, J.A.10
Cheetham, C.H.11
Earley, A.K.12
Barnett, A.H.13
Prins, J.B.14
O'Rahilly, S.15
-
12
-
-
9344241376
-
Phenotrype of fatty due to Gln269Pro mutation in the leptin receptor (LepR)
-
Chua SC Jr, White DW, Wu-Peng XS, Liu SM, Okada N, Kershaw EE, Chung WK, Power-Kehoe L, Chua M, Tartaglia LA, Leibel RL: Phenotrype of fatty due to Gln269Pro mutation in the leptin receptor (LepR). Diabetes 45:1141-1143, 1996
-
(1996)
Diabetes
, vol.45
, pp. 1141-1143
-
-
Chua Jr., S.C.1
White, D.W.2
Wu-Peng, X.S.3
Liu, S.M.4
Okada, N.5
Kershaw, E.E.6
Chung, W.K.7
Power-Kehoe, L.8
Chua, M.9
Tartaglia, L.A.10
Leibel, R.L.11
-
13
-
-
0030960861
-
Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene
-
Good DJ, Porter FD, Mahon KA, Parlow AF, Westphal H, Kirsch IR: Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nat Genet 15:397-401, 1997
-
(1997)
Nat Genet
, vol.15
, pp. 397-401
-
-
Good, D.J.1
Porter, F.D.2
Mahon, K.A.3
Parlow, A.F.4
Westphal, H.5
Kirsch, I.R.6
-
14
-
-
0030949271
-
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
-
Jackson KS, Creemers JWM, Ohagi S, Raffin-Sanson M-L, Sanders L, Montague CT, Hutton JC, O'Rahilly S: Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Nature Genetics 16:303-306, 1997
-
(1997)
Nature Genetics
, vol.16
, pp. 303-306
-
-
Jackson, K.S.1
Creemers, J.W.M.2
Ohagi, S.3
Raffin-Sanson, M.-L.4
Sanders, L.5
Montague, C.T.6
Hutton, J.C.7
O'Rahilly, S.8
-
15
-
-
0029040210
-
Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity
-
Naggert JK, Flicker LD, Varlamov O, Nishina PM, Rouille Y, Steiner DF, Carroll RJ, Paigen BJ, Leiter EH: Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity. Nature Genetics 10:135-142, 1995
-
(1995)
Nature Genetics
, vol.10
, pp. 135-142
-
-
Naggert, J.K.1
Flicker, L.D.2
Varlamov, O.3
Nishina, P.M.4
Rouille, Y.5
Steiner, D.F.6
Carroll, R.J.7
Paigen, B.J.8
Leiter, E.H.9
-
16
-
-
0030976604
-
Carboxypeptidase E is a regulated sewtory pathway sorting receptor generic obliteration leads to endocrine disorders in Cpe(fat) mice
-
Cool DR, Normant E, Shea F, Chen HC, Pannell L, Zhang Y, Loh YP: Carboxypeptidase E is a regulated sewtory pathway sorting receptor generic obliteration leads to endocrine disorders in Cpe(fat) mice. Cell 88:73-83, 1997
-
(1997)
Cell
, vol.88
, pp. 73-83
-
-
Cool, D.R.1
Normant, E.2
Shea, F.3
Chen, H.C.4
Pannell, L.5
Zhang, Y.6
Loh, Y.P.7
-
17
-
-
0026571601
-
Virus-induced obesity in mice: Association with a hypothalamic lesion
-
Nagashima K, Zabriskie JB, Lyons MJ: Virus-induced obesity in mice: association with a hypothalamic lesion. J Neuropathol Exp Neurol 51:101-109, 1992
-
(1992)
J Neuropathol Exp Neurol
, vol.51
, pp. 101-109
-
-
Nagashima, K.1
Zabriskie, J.B.2
Lyons, M.J.3
-
18
-
-
0026045936
-
Age-related changes in proopiontelanocortin (POMC) gene expression in the periarcuate region of ovariectomized rats
-
Lloyd JM, Scarborough K, Weiland NO, Wise PM: Age-related changes in proopiontelanocortin (POMC) gene expression in the periarcuate region of ovariectomized rats. Endocrinology 129:1896-1902, 1901
-
(1901)
Endocrinology
, vol.129
, pp. 1896-1902
-
-
Lloyd, J.M.1
Scarborough, K.2
Weiland, N.O.3
Wise, P.M.4
-
19
-
-
0030001086
-
Chronic food restriction and acute food deprivation decrease inRNA levels of opioid peptides in arcuate nucleus
-
Kim EM, Welch CC, Grace MK, Billington CJ, Levine AS: Chronic food restriction and acute food deprivation decrease inRNA levels of opioid peptides in arcuate nucleus. Am J Physiol 270:R1019-R1024, 1996
-
(1996)
Am J Physiol
, vol.270
-
-
Kim, E.M.1
Welch, C.C.2
Grace, M.K.3
Billington, C.J.4
Levine, A.S.5
-
20
-
-
0025038674
-
Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats
-
Brady LS, Smith MA, Gold PW, Herkenham M: Altered expression of hypothalamic neuropeptide mRNAs in food-restricted and food-deprived rats. Neuroendocrinology 52:441-447, 1990
-
(1990)
Neuroendocrinology
, vol.52
, pp. 441-447
-
-
Brady, L.S.1
Smith, M.A.2
Gold, P.W.3
Herkenham, M.4
-
21
-
-
0030737953
-
Physiological response to long-term peripheral and central leptin infusion in lean and obese mice
-
Halaas JL, Boozer C, Blair-West J, Fidahusein N, Denton DA, Friedman JM: Physiological response to long-term peripheral and central leptin infusion in lean and obese mice, Proc Natl Acad Sci USA 94:8878-8883, 1097
-
(1097)
Proc Natl Acad Sci USA
, vol.94
, pp. 8878-8883
-
-
Halaas, J.L.1
Boozer, C.2
Blair-West, J.3
Fidahusein, N.4
Denton, D.A.5
Friedman, J.M.6
-
22
-
-
0021060527
-
Identification of proopiomelanocortin neurones in rat hypothalamus by in situ cDNA-mRNA hybridization
-
Gee CE, Chen CL, Roberts JL, Thompson H, Watson SJ: Identification of proopiomelanocortin neurones in rat hypothalamus by in situ cDNA-mRNA hybridization. Nature 306:374-376, 1983
-
(1983)
Nature
, vol.306
, pp. 374-376
-
-
Gee, C.E.1
Chen, C.L.2
Roberts, J.L.3
Thompson, H.4
Watson, S.J.5
-
23
-
-
0030894113
-
The arcuate nucleus as a primary site of satiety effect of leptin in rats
-
Satoh N, Ogawa Y, Katsuura G, Hayase M, Tsuji T Imagawa K, Yoahimasa Y, Nishi S, Hosoda K, Nakao K: The arcuate nucleus as a primary site of satiety effect of leptin in rats. Neurosci Lett 224:149-152, 1997
-
(1997)
Neurosci Lett
, vol.224
, pp. 149-152
-
-
Satoh, N.1
Ogawa, Y.2
Katsuura, G.3
Hayase, M.4
Imagawa K, T.T.5
Yoahimasa, Y.6
Nishi, S.7
Hosoda, K.8
Nakao, K.9
-
24
-
-
2642639411
-
Coexpression of leptin receptor (OB-R) mRNA with POMC and NPY in the central nervous system of the rat
-
Cheung CC, Thornton JE, Clifton DK, Steiner RA: Coexpression of leptin receptor (OB-R) mRNA with POMC and NPY in the central nervous system of the rat (Abstract). Endocr Soc Abstr 79:379, 1997
-
(1997)
Endocr Soc Abstr
, vol.79
, pp. 379
-
-
Cheung, C.C.1
Thornton, J.E.2
Clifton, D.K.3
Steiner, R.A.4
-
25
-
-
13344279395
-
A role for melanin-con-centrating hormone in the central regulation of feeding behavior
-
Qu D, Ludwig DS, Gammeltoft S, Piper M, Pelleymounter MA, Cullen MJ, Mathes WF, Przypek R, Kanarck R, Maratos-Flier E: A role for melanin-con-centrating hormone in the central regulation of feeding behavior. Nature 380:243-247, 1996
-
(1996)
Nature
, vol.380
, pp. 243-247
-
-
Qu, D.1
Ludwig, D.S.2
Gammeltoft, S.3
Piper, M.4
Pelleymounter, M.A.5
Cullen, M.J.6
Mathes, W.F.7
Przypek, R.8
Kanarck, R.9
Maratos-Flier, E.10
-
26
-
-
0030919781
-
Melanin-concentrating hormone (MCH) antagonizes the effects of alpha-MSH and neuropeptide E-I on grooming and locomotor activities in the rat
-
Sanchez M, Baker BI, Cells M: Melanin-concentrating hormone (MCH) antagonizes the effects of alpha-MSH and neuropeptide E-I on grooming and locomotor activities in the rat. Peptides 18:393-396, 1997
-
(1997)
Peptides
, vol.18
, pp. 393-396
-
-
Sanchez, M.1
Baker, B.I.2
Cells, M.3
-
27
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS: Role of leptin in the neuroendocrine response to fasting. Nature 382:250-252, 1996
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
Flier, J.S.7
|