Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity

Advanced Drug Delivery Reviews

Volumn 58, Issue 14, 2006, Pages 1523-1531

  Hunter, A Christy ^a  

^a UNIVERSITY OF BRIGHTON   (United Kingdom)

Author keywords

Apoptosis; Biodegradable polymer; Gene therapy; Gene transfection; MTT assay; Poly(ethylenimine); Poly(l lysine); Polyfectin; Polymer toxicity

Indexed keywords

CELLS; DNA; MACROMOLECULES; NANOSTRUCTURED MATERIALS; ORGANIC POLYMERS; POSITIVE IONS; RESEARCH AND DEVELOPMENT MANAGEMENT; RNA;

APOPTOSIS; BIODEGRADABLE POLYMERS; GENE THERAPY; GENE TRANSFECTION; MTT ASSAYS; POLYETHYLENIMINE; POLYFECTIN; POLYL-LYSINE; POLYMER TOXICITY;

GENETIC ENGINEERING;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; DENDRIMER; FLOCOR; MACROGOL; POLOXAMER; POLY(2 DIMETHYLAMINO)ETHYLMETHACRYLATE; POLYAMIDOAMINE; POLYCATION; POLYETHYLENEIMINE; POLYFECTIN; POLYGLACTIN; POLYLYSINE; POLYMER;

CLINICAL TRIAL; CYTOTOXICITY; GENE THERAPY; GENETIC TRANSFECTION; HUMAN; IN VIVO STUDY; MACROMOLECULE; NEPHROTOXICITY; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; REVIEW;

ANIMALS; APOPTOSIS; CELL LINE; GENE TRANSFER TECHNIQUES; HUMANS; POLYAMINES; POLYETHYLENEIMINE; POLYLYSINE; TETRAZOLIUM SALTS; THIAZOLES;

EID: 33751404700     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2006.09.008     Document Type: Review

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