Nonviral gene delivery to the rat kidney with polyethylenimine

Human Gene Therapy

Volumn 8, Issue 10, 1997, Pages 1243-1251

  Boletta, Alessandra ^a   Benigni, Ariela ^a   Lutz, Jens ^a   Remuzzi, Giuseppe ^a   Soria, Marco R ^b   Monaco, Lucia ^b  

^a MARIO NEGRI INST PHARMACOL RES   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CATION; LIPID; LUCIFERASE; POLYETHYLENEIMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; GENE TARGETING; KIDNEY; NONHUMAN; RAT; RENAL ARTERY; REPORTER GENE; TARGET ORGAN; TRANSGENE;

ANIMALIA;

EID: 0030825116     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.10-1243     Document Type: Article

References (35)

1. ABDALLAH, B., SACHS, L., and DEMENEIX, B.A. (1995). Non-viral gene transfer-applications in developmental biology and gene therapy. Biol. Cell 85, 1-7.
2. ABDALLAH, B., HASSAN, A., BENOIST, C., GOULA, D., BEHR, J.P., and DEMENEIX, B.A. (1996). A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain polyethylenimine. Hum. Gene Ther. 7, 1947-1954.
3. AKAMI, T., ARAKAWA, K., OKAMOTO, M., AKIOKA, K., FUJIWARA, I., NAKAI, I., MITSUO, M., TOMITA, N., KANEDA, Y., TANAKA, K., and OKA, T. (1994). Introduction and expression of human CD59 gene in the canine kidney. Transplant. Proc. 26, 1315-1317.
4. BEHR, J.P. (1994). Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy. Bioconjug. Chem. 5, 382-389.
5. BEHR, J.P., DEMENEIX, B., LOEFFLER, J.P., and PEREZ-MUTUL, J. (1989). Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA. Proc. Natl. Acad. Sci. USA 86, 6982-6986.
6. BOSCH, R.J., WOOLF, A.S., and FINE, L.G. (1993). Gene transfer into the mammalian kidney: direct retrovirus-transduction of regenerating tubular epithelial cells. Exp. Nephrol. 1, 49-54.
7. BOUSSIF, O., LEZOUALC'H, F., ZANTA, M.A., MERGNY, M.D., SCHERMAN, D., DEMENEIX, B., and BEHR, J.P. (1995). A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc. Natl. Acad. Sci. USA 92, 7297-7301.
8. CAPLEN, N.J., KINRADE, E., SORGI, F., GAO, X., GRUENERT, D., GEDDES, D., COUTELLE, C., HUANG, L., ALTON, E.W., and WILLIAMSON, R. (1995). In vitro liposome-mediated DNA transfection of epithelial cell lines using the cationic liposome DC-Chol/DOPE. Gene Ther. 2, 603-13.
9. FELGNER, P.L., GADEK, T.R., HOLM, M., ROMAN, R., CHAN, H.W., WENZ, M., NORTHROP, J.P., RINGOLD, G.M., and DANIELSEN, M. (1987). Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA 84, 7413-7417.
10. GAO, X., and HUANG, L. (1991). A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem. Biophys. Res. Commun. 179, 280-285.
11. GLAUMANN, B., GLAUMANN, H., BEREZESKY, I.K., and TRUMP, B.F. (1977). Studies on cellular recovery from injury. II. Ultrastructural studies on the recovery of the pars convoluta of the proximal tubule of the rat kidney from temporary ischemia. Virchows Arch. B. Cell. Pathol. 24, 1-18.
12. HAENSLER, J., and SZOKA, F.C., JR. (1993). Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug. Chem. 4, 372-379.
13. HEIKKILA, P., PARPALA, T., LUKKARINEN, O., WEBER, M., and TRYGGVASON, K. (1996). Adenovirus-mediated gene transfer into kidney glomeruli using an ex vivo and in vivo kidney perfusion system-first steps towards gene therapy of Alport syndrome. Gene Ther. 3, 21-27.
14. ISAKA, Y., FUJIWARA, Y., UEDA, N., KANEDA, Y., KAMADA, T., and IMAI, E. (1993). Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney. J. Clin. Invest. 92, 2597-2601.
15. KITAMURA, M., TAYLOR, S., UNWIN, R., BURTON, S., SHIMIZU, F., and FINE, L.G. (1994). Gene transfer into the rat renal glomerulus via a mesangial cell vector: site-specific delivery, in situ amplification, and sustained expression of an exogenous gene in vivo. J. Clin. Invest. 94, 497-505.
16. KOSEKI, C., HERZLINGER, D., and AL-AWQATI, Q. (1991). Integration of embyronic nephrogenic cells carrying a reporter gene into functioning nephrons. Am. J. Physiol. 261, C550-C554.
17. LEW, D., PARKER, S.E., LATIMER, T., ABAI, A.M., KUWAHARA-RUNDELL, A., DOH, S.G., YANG, Z.Y., LAFACE, D., GROMKOWSKI, S.H., NABEL, G.J., MANTHORPE, M., and NORMAN, J. (1995). Cancer gene therapy using plasmid DNA: pharmacokinetic study of DNA following injection in mice. Hum. Gene Ther. 6, 553-564.
18. MEYER, K.B., THOMPSON, M.M., LEVY, M.Y., BARRON, L.G., and SZOKA, F.C.J. (1995). Intratracheal gene delivery to the mouse airway: Characterization of plasmid DNA expression and pharmacokinetics. Gene Ther. 2, 450-460.
19. MONACO, L., TAGLIABUE, R., SORIA, M.R., and UHLEN, M. (1994). An in vitro amplification approach for the expression of recombinant proteins in mammalian cells. Biotechnol. Appl. Biochem. 20, 157-171.
20. MONACO, L., TAGLIABUE, R., GIOVANAZZI, S., BRAGONZI, A., and SORIA, M.R. (1996). Expression of human granulocyte colony-stimulating factor in CHO dhfr- cells: new insights into the in vitro amplification expression system. Gene 180, 145-150.
21. MOORE, K.J., NAITO, T., MARTIN, C., and KELLEY, V.R. (1996a). Enhanced response of macrophages to CSF-1 in autoimmune mice-a gene transfer strategy. J. Immunol. 157, 433-440.
22. MOORE, K.J., YEH, K., NAITO, T., and KELLEY, V.R. (1996b). TNF-alpha enhances colony-stimulating factor-1-Induced macrophage accumulation in autoimmune renal disease. J. Immunol. 157, 427-432.
23. MOULLIER, P., FRIEDLANDER, G., CALISE, D., RONCO, P., PERRICAUDET, M., and FERRY, N. (1994). Adenoviral-mediated gene transfer to renal tubular cells in vivo. Kidney Int. 45, 1220-1225.
24. NABEL, E.G., YANG, Z., MULLER, D., CHANG, A.E., GAO, X., HUANG, L., CHO, K.J., and NABEL, G.J. (1994). Safety and toxicity of catheter gene delivery to the pulmonary vasculature in a patient with metastatic melanoma. Hum. Gene Ther. 5, 1089-1094.
25. NABEL, G.J., NABEL, E.G., YANG, Z.Y., FOX, B.A., PLAUTZ, G.E., GAO, X., HUANG, L., SHU, S., GORDON, D., and CHANG, A.E. (1993). Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc. Natl. Acad. Sci. USA 90, 11307-11311.
26. PASQUALINI, R., and RUOSLAHTI, E. (1996). Organ targeting in vivo using phage display peptide libraries. Nature 380, 364-366.
27. SAMBROOK, J., FRITSCH, E.F., and MANIATIS, T. (1989). Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY).
28. SCHWARTZ, B., BENOIST, C., ABDALLAH, B., SCHERMAN, D., BEHR, J.P., and DEMENEIX, B.A. (1995). Lipospermine-based gene transfer into the newborn mouse brain is optimized by a low lipospermine/DNA charge ratio. Hum. Gene Ther. 6, 1515-1524.
29. SUH, J., PAIK, H.J., and HWANG, B.K. (1994). Ionization of poly(ethylenimine) and poly(allylamine) at various pH's. Bioorg. Chem. 22, 318-327.
30. TOMITA, N., HIGAKI, J., MORISHITA, R., KATO, K., MIKAMI, H., KANEDA, Y., and OGIHARA, T. (1992). Direct in vivo gene introduction into rat kidney. Biochem. Biophys. Res. Commun. 186, 129-134.
31. WINER, B.J. (1971). Statistical Principles in Experimental Design. (McGraw Hill, New York).
32. WOLFF, J.A., MALONE, R.W., WILLIAMS, P., CHONG, W., ACSADI, G., JANI, A., and FELGNER, P.L. (1990). Direct gene transfer into mouse muscle in vivo. Science 247, 1465-1468.
33. WOOLF, A.S., BOSCH, R.J., and FINE, L.G. (1993). Gene transfer into the mammalian kidney: microtransplantation of retrovirus-transduced metanephric tissue. Exp. Nephrol. 1, 41-48.
34. ZHU, G., NICOLSON, A.G., COWLEY, B.D., ROSEN, S., and SUKHATME, V.P. (1996). In vivo adenovirus-mediated gene transfer into normal and cystic rat kidneys. Gene Ther. 3, 298-304.
35. ZHU, N., LIGGIT, D., LIU, Y., and DEBS, R. (1993). Systemic gene expression after intravenous DNA delivery into adult mice. Science 261, 209-211.