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Volumn 317, Issue 3, 2006, Pages 1382-1390

Evaluation of proinflammatory cytokine production induced by linear and branched polyethylenimine/plasmid DNA complexes in mice

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; AMMONIUM CHLORIDE; CHOLESTEROL; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; LIPOSOME; N [1 (2,3 DIOLEYLOXY)PROPYL] N,N,N TRIMETHYLAMMONIUM CHLORIDE; NITROGEN; PHOSPHATE; PLASMID DNA; POLYETHYLENEIMINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 33646814034     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.100669     Document Type: Article
Times cited : (97)

References (41)
  • 1
    • 19744372388 scopus 로고    scopus 로고
    • Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
    • Akinc A, Thomas M, Klibanov AM, and Langer R (2005) Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J Gene Med 7:657-663.
    • (2005) J Gene Med , vol.7 , pp. 657-663
    • Akinc, A.1    Thomas, M.2    Klibanov, A.M.3    Langer, R.4
  • 2
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ and Karin M (1997) Nuclear factor-κB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071.
    • (1997) N Engl J Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 6
    • 0036371914 scopus 로고    scopus 로고
    • Side-effects of a systemic injection of linear polyethylenimine-DNA complexes
    • Chollet P, Favrot MC, Hurbin A, and Coll JL (2002) Side-effects of a systemic injection of linear polyethylenimine-DNA complexes. J Gene Med 4:84-91.
    • (2002) J Gene Med , vol.4 , pp. 84-91
    • Chollet, P.1    Favrot, M.C.2    Hurbin, A.3    Coll, J.L.4
  • 7
    • 0034667770 scopus 로고    scopus 로고
    • Phosphorothioate backbone modification modulates macrophage activation by CpG DNA
    • David PS, Shalin N, Shannon JB, David AH, and Katryn JS (2000) Phosphorothioate backbone modification modulates macrophage activation by CpG DNA. J Immunol 165:4165-4173.
    • (2000) J Immunol , vol.165 , pp. 4165-4173
    • David, P.S.1    Shalin, N.2    Shannon, J.B.3    David, A.H.4    Katryn, J.S.5
  • 9
    • 27144475378 scopus 로고    scopus 로고
    • Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex
    • Fumoto S, Kawakami S, Shigeta K, Higuchi Y, Yamashita F, and Hashida M (2005) Interaction with blood components plays a crucial role in asialoglycoprotein receptor-mediated in vivo gene transfer by galactosylated lipoplex. J Pharmacol Exp Ther 315:484-493.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 484-493
    • Fumoto, S.1    Kawakami, S.2    Shigeta, K.3    Higuchi, Y.4    Yamashita, F.5    Hashida, M.6
  • 10
    • 0031720533 scopus 로고    scopus 로고
    • Polyethylenimine-based intravenous delivery of transgenes to mouse lung
    • Goula D, Benoist C, Mantero S, Merlo G, Levi G, and Demeneix BA (1998) Polyethylenimine-based intravenous delivery of transgenes to mouse lung. Gene Ther 5:1291-1295.
    • (1998) Gene Ther , vol.5 , pp. 1291-1295
    • Goula, D.1    Benoist, C.2    Mantero, S.3    Merlo, G.4    Levi, G.5    Demeneix, B.A.6
  • 12
    • 0034000572 scopus 로고    scopus 로고
    • In vivo gene delivery to the liver using novel galactosylated cationic liposomes
    • Kawakami S, Fumoto S, Nishikawa M, Yamashita F, and Hashida M (2000a) In vivo gene delivery to the liver using novel galactosylated cationic liposomes. Pharm Res (N Y) 17:306-313.
    • (2000) Pharm Res (N Y) , vol.17 , pp. 306-313
    • Kawakami, S.1    Fumoto, S.2    Nishikawa, M.3    Yamashita, F.4    Hashida, M.5
  • 13
    • 0033995526 scopus 로고    scopus 로고
    • Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes
    • Kawakami S, Sato A, Nishikawa M, Yamashita F, and Hashida M (2000b) Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes. Gene Ther 7:292-299.
    • (2000) Gene Ther , vol.7 , pp. 292-299
    • Kawakami, S.1    Sato, A.2    Nishikawa, M.3    Yamashita, F.4    Hashida, M.5
  • 14
    • 0035131596 scopus 로고    scopus 로고
    • Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
    • Kircheis R, Wightman L, Schreiber A, Robitza B, Rossler V, Kursa M, and Wagner E (2001) Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 8:28-40.
    • (2001) Gene Ther , vol.8 , pp. 28-40
    • Kircheis, R.1    Wightman, L.2    Schreiber, A.3    Robitza, B.4    Rossler, V.5    Kursa, M.6    Wagner, E.7
  • 15
    • 0035286969 scopus 로고    scopus 로고
    • Polyethylenimine-mediated gene delivery: A mechanistic study
    • Kichler A, Leborgne C, Coeytaux E, and Danos O (2001) Polyethylenimine-mediated gene delivery: a mechanistic study. J Gene Med 3:135-144.
    • (2001) J Gene Med , vol.3 , pp. 135-144
    • Kichler, A.1    Leborgne, C.2    Coeytaux, E.3    Danos, O.4
  • 16
    • 1842631153 scopus 로고    scopus 로고
    • Immunotherapeutic uses of CpG oligodeoxynucleotides
    • Klinman DM (2004) Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat Rev Immunol 4:1-10.
    • (2004) Nat Rev Immunol , vol.4 , pp. 1-10
    • Klinman, D.M.1
  • 17
    • 0029100239 scopus 로고
    • A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
    • Knowles MR, Hohneker KW, Zhou Z, Olsen JC, Noah TL, Hu PC, Leigh MW, and Boucher RC (1995) A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. N Engl J Med 333:823-831.
    • (1995) N Engl J Med , vol.333 , pp. 823-831
    • Knowles, M.R.1    Hohneker, K.W.2    Zhou, Z.3    Olsen, J.C.4    Noah, T.L.5    Hu, P.C.6    Leigh, M.W.7    Boucher, R.C.8
  • 19
    • 0024475227 scopus 로고
    • NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control
    • Lenardo MJ and Baltimore D (1989) NF-κB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58:227-229.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.J.1    Baltimore, D.2
  • 21
    • 0030813879 scopus 로고    scopus 로고
    • Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration
    • Liu F, Qi H, Huang L, and Liu D (1997) Factors controlling the efficiency of cationic lipid-mediated transfection in vivo via intravenous administration. Gene Ther 6:517-523.
    • (1997) Gene Ther , vol.6 , pp. 517-523
    • Liu, F.1    Qi, H.2    Huang, L.3    Liu, D.4
  • 22
    • 0035831629 scopus 로고    scopus 로고
    • Contribution of plasmid DNA to hepatotoxicity after systemic administration of lipoplexes
    • Loisel S, Le Gall C, Doucet L, Ferec C, and Floch V (2001) Contribution of plasmid DNA to hepatotoxicity after systemic administration of lipoplexes. Hum Gene Ther 12:685-696.
    • (2001) Hum Gene Ther , vol.12 , pp. 685-696
    • Loisel, S.1    Le Gall, C.2    Doucet, L.3    Ferec, C.4    Floch, V.5
  • 23
    • 19444372923 scopus 로고    scopus 로고
    • A two-stage poly(ethylenimine)-mediated cytotoxicity: Implications for gene transfer/therapy
    • Moghimi SM, Symonds P, Murray JC, Hunter AC, Debska G, and Szewczyk A (2005) A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy. Mol Ther 11:990-995.
    • (2005) Mol Ther , vol.11 , pp. 990-995
    • Moghimi, S.M.1    Symonds, P.2    Murray, J.C.3    Hunter, A.C.4    Debska, G.5    Szewczyk, A.6
  • 24
    • 0037301583 scopus 로고    scopus 로고
    • Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethylenimine on hepatoma cells and mouse liver
    • Morimoto K, Nishikawa M, Kawakami S, Nakano T, Hattori Y, Fumoto S, Yamashita F, and Hashida M (2003) Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethylenimine on hepatoma cells and mouse liver. Mol Ther 7:254-261.
    • (2003) Mol Ther , vol.7 , pp. 254-261
    • Morimoto, K.1    Nishikawa, M.2    Kawakami, S.3    Nakano, T.4    Hattori, Y.5    Fumoto, S.6    Yamashita, F.7    Hashida, M.8
  • 25
    • 23944464631 scopus 로고    scopus 로고
    • Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives
    • Neu M, Fischer D, and Kissel T (2005) Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives. J Gene Med 7:992-1009.
    • (2005) J Gene Med , vol.7 , pp. 992-1009
    • Neu, M.1    Fischer, D.2    Kissel, T.3
  • 27
    • 17844401203 scopus 로고    scopus 로고
    • Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: The role of the neutral helper lipid
    • Sakurai F, Nishioka T, Saito H, Baba T, Okuda A, Matsumoto O, Taga T, Yamashita F, Takakura Y, and Hashida M (2001) Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid. Gene Ther 8:677-686.
    • (2001) Gene Ther , vol.8 , pp. 677-686
    • Sakurai, F.1    Nishioka, T.2    Saito, H.3    Baba, T.4    Okuda, A.5    Matsumoto, O.6    Taga, T.7    Yamashita, F.8    Takakura, Y.9    Hashida, M.10
  • 28
    • 0036060566 scopus 로고    scopus 로고
    • The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes
    • Sakurai F, Terada T, Yasuda K, Yamashita F, Takakura Y, and Hashida M (2002) The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes. Gene Ther 9:1120-1126.
    • (2002) Gene Ther , vol.9 , pp. 1120-1126
    • Sakurai, F.1    Terada, T.2    Yasuda, K.3    Yamashita, F.4    Takakura, Y.5    Hashida, M.6
  • 29
    • 0030668116 scopus 로고    scopus 로고
    • Characterization of cationic liposomemediated gene transfer in vivo by intravenous administration
    • Song YK, Liu F, Chu SY, and Liu D (1997) Characterization of cationic liposomemediated gene transfer in vivo by intravenous administration. Hum Gene Ther 8:1585-1594.
    • (1997) Hum Gene Ther , vol.8 , pp. 1585-1594
    • Song, Y.K.1    Liu, F.2    Chu, S.Y.3    Liu, D.4
  • 30
    • 0034991899 scopus 로고    scopus 로고
    • Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity
    • Tan Y, Liu F, Li Z, Li S, and Huang L (2001) Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity. Mol Ther 3:673-682.
    • (2001) Mol Ther , vol.3 , pp. 673-682
    • Tan, Y.1    Liu, F.2    Li, Z.3    Li, S.4    Huang, L.5
  • 31
    • 0036936852 scopus 로고    scopus 로고
    • Codelivery of NF-κB decoy-related oligodeoxynucleotide improves LPD-mediated systemic gene transfer
    • Tan Y, Zhang JS, and Huang L (2002) Codelivery of NF-κB decoy-related oligodeoxynucleotide improves LPD-mediated systemic gene transfer. Mol Ther 6:804-812.
    • (2002) Mol Ther , vol.6 , pp. 804-812
    • Tan, Y.1    Zhang, J.S.2    Huang, L.3
  • 34
    • 0032732516 scopus 로고    scopus 로고
    • LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth
    • Whitmore M, Li S, and Huang L (1999) LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth. Gene Ther 6:1867-1875.
    • (1999) Gene Ther , vol.6 , pp. 1867-1875
    • Whitmore, M.1    Li, S.2    Huang, L.3
  • 35
    • 0035408714 scopus 로고    scopus 로고
    • Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo
    • Wightman L, Kircheis R, Rossler V, Carotta S, Ruzicka R, Kursa M, and Wagner E (2001) Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo. J Gene Med 3:362-372.
    • (2001) J Gene Med , vol.3 , pp. 362-372
    • Wightman, L.1    Kircheis, R.2    Rossler, V.3    Carotta, S.4    Ruzicka, R.5    Kursa, M.6    Wagner, E.7
  • 36
    • 0030759050 scopus 로고    scopus 로고
    • Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA
    • Yang JP and Huang L (1997) Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA. Gene Ther 4:950-960.
    • (1997) Gene Ther , vol.4 , pp. 950-960
    • Yang, J.P.1    Huang, L.2
  • 39
    • 0034149827 scopus 로고    scopus 로고
    • Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs
    • Yew NS, Zhao H, Wu IH, Song A, Tousignant JD, Przybylska M, and Cheng SH (2000) Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs. Mol Ther 1:255-262.
    • (2000) Mol Ther , vol.1 , pp. 255-262
    • Yew, N.S.1    Zhao, H.2    Wu, I.H.3    Song, A.4    Tousignant, J.D.5    Przybylska, M.6    Cheng, S.H.7
  • 40
    • 0032525023 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species
    • Yi AK, Tuetken R, Redford T, Waldschmidt M, Kirsch J, and Krieg AM (1998) CpG motifs in bacterial DNA activate leukocytes through the pH-dependent generation of reactive oxygen species. J Immunol 160:4755-4761.
    • (1998) J Immunol , vol.160 , pp. 4755-4761
    • Yi, A.K.1    Tuetken, R.2    Redford, T.3    Waldschmidt, M.4    Kirsch, J.5    Krieg, A.M.6
  • 41
    • 0034152683 scopus 로고    scopus 로고
    • Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse
    • Zou SM, Erbacher P, Remy JS, and Behr JP (2000) Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse. J Gene Med 2:128-134.
    • (2000) J Gene Med , vol.2 , pp. 128-134
    • Zou, S.M.1    Erbacher, P.2    Remy, J.S.3    Behr, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.