메뉴 건너뛰기




Volumn 22, Issue 1, 2005, Pages 1-10

Polyethylene glycol-conjugated copolymers for plasmid DNA delivery

Author keywords

Cationic polymer; Gene delivery; Gene therapy; Polyethylene glycol; Polymeric gene carriers

Indexed keywords

CATION; COPOLYMER; DRUG CARRIER; LIGAND; MACROGOL; PLASMA PROTEIN; PLASMID DNA;

EID: 17644395943     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-004-9003-5     Document Type: Review
Times cited : (249)

References (63)
  • 1
    • 4444370799 scopus 로고    scopus 로고
    • Gene therapy clinical trials worldwide 1989-2004 - An overview
    • M. L. Edelstein, M. R. Abedi, J. Wixon, and R. M. Edelstein. Gene therapy clinical trials worldwide 1989-2004 - an overview. J. Gene Med. 6:597-602 (2004).
    • (2004) J. Gene Med. , vol.6 , pp. 597-602
    • Edelstein, M.L.1    Abedi, M.R.2    Wixon, J.3    Edelstein, R.M.4
  • 2
    • 0042694402 scopus 로고    scopus 로고
    • Polymeric gene carriers
    • M. Lee and S. W. Kim. Polymeric gene carriers. Pharm. News 9:407-415 (2002).
    • (2002) Pharm. News , vol.9 , pp. 407-415
    • Lee, M.1    Kim, S.W.2
  • 3
    • 0023212742 scopus 로고
    • Receptor-mediated in vitro gene transformation by a soluble DNA carrier system
    • G. Y. Wu and C. H. Wu. Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. J. Biol. Chem. 262: 4429-4432 (1987).
    • (1987) J. Biol. Chem. , vol.262 , pp. 4429-4432
    • Wu, G.Y.1    Wu, C.H.2
  • 4
    • 0024282306 scopus 로고
    • Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro
    • G. Y. Wu and C. H. Wu. Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro. Biochemistry 27:887-892 (1988).
    • (1988) Biochemistry , vol.27 , pp. 887-892
    • Wu, G.Y.1    Wu, C.H.2
  • 5
    • 0026315433 scopus 로고
    • Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats
    • G. Y. Wu, J. M. Wilson, F. Shalaby, M. Grossman, D. A. Shafritz, and C. H. Wu. Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats. J. Biol. Chem. 266:14338-14342 (1991).
    • (1991) J. Biol. Chem. , vol.266 , pp. 14338-14342
    • Wu, G.Y.1    Wilson, J.M.2    Shalaby, F.3    Grossman, M.4    Shafritz, D.A.5    Wu, C.H.6
  • 6
    • 0347170870 scopus 로고    scopus 로고
    • Introduction to chemistry and biological applications of poly(ethylene glycol)
    • J. M. Harris and S. Zalipsky (eds.), ACS Symposium Series. American Chemical Society, Washington, DC
    • S. Zalipsky and J. M. Harris. Introduction to chemistry and biological applications of poly(ethylene glycol). In J. M. Harris and S. Zalipsky (eds.), Poly(ehtylene glycol): Chemistry and Biological Applications, Vol. 680. ACS Symposium Series. American Chemical Society, Washington, DC, 1997, pp. 1-13.
    • (1997) Poly(ehtylene Glycol): Chemistry and Biological Applications , vol.680 , pp. 1-13
    • Zalipsky, S.1    Harris, J.M.2
  • 7
    • 0025891831 scopus 로고
    • Transferrin-polycation-DNA complexes: The effect of polycations on the structure of the complex and DNA delivery to cells
    • E. Wagner, M. Cotton, R. Foisner, and M. L. Birnstiel. Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells. Proc. Natl. Acad. Sci. USA 88:4255-4259 (1991).
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4255-4259
    • Wagner, E.1    Cotton, M.2    Foisner, R.3    Birnstiel, M.L.4
  • 8
    • 0345118151 scopus 로고    scopus 로고
    • Water soluble lipopolymer as an efficient carrier for gene delivery to myocardium
    • M. Lee, J. Rentz, S. Han, D. A. Bull, and S. W. Kim. Water soluble lipopolymer as an efficient carrier for gene delivery to myocardium. Gene Ther. 10:585-593 (2003).
    • (2003) Gene Ther. , vol.10 , pp. 585-593
    • Lee, M.1    Rentz, J.2    Han, S.3    Bull, D.A.4    Kim, S.W.5
  • 9
    • 0037130190 scopus 로고    scopus 로고
    • Poly(L-lysine)-g-poly(D, L-lactic-coglycolic acid) micelles for low cytotoxic biodegradable gene carriers
    • J. H. Jeong and T. G. Park. Poly(L-lysine)-g-poly(D, L-lactic-coglycolic acid) micelles for low cytotoxic biodegradable gene carriers. J. Control. Rel. 82:159-166 (2002).
    • (2002) J. Control. Rel. , vol.82 , pp. 159-166
    • Jeong, J.H.1    Park, T.G.2
  • 11
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • M. Ogris, S. Brunner, S. Schuller, R. Kircheis, and E. Wagner. PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. 6:595-605 (1999).
    • (1999) Gene Ther. , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 12
    • 0030865986 scopus 로고    scopus 로고
    • Synthetic polymers for vectorial delivery of DNA: Characterisation of polymer-DNA complexes by photon correlation spectroscopy and stability to nuclease degradation and disruption by polyanions in vitro
    • P. R. Dash, V. Toncheva, E. Schacht, and L. W. Seymour. Synthetic polymers for vectorial delivery of DNA: characterisation of polymer-DNA complexes by photon correlation spectroscopy and stability to nuclease degradation and disruption by polyanions in vitro. J. Control. Rel. 48:269-276 (1997).
    • (1997) J. Control. Rel. , vol.48 , pp. 269-276
    • Dash, P.R.1    Toncheva, V.2    Schacht, E.3    Seymour, L.W.4
  • 13
    • 0029136052 scopus 로고
    • DNA complexes with polycations for the delivery of genetic material into cells
    • A. V. Kabanov and V. A. Kabanov. DNA complexes with polycations for the delivery of genetic material into cells. Bioconjug. Chem. 6:7-20 (1995).
    • (1995) Bioconjug. Chem. , vol.6 , pp. 7-20
    • Kabanov, A.V.1    Kabanov, V.A.2
  • 14
    • 0029801424 scopus 로고    scopus 로고
    • Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers
    • M. A. Wolfert, E. H. Schacht, V. Toncheva, K. Ulbrich, O. Nazarova, and L. W. Seymour. Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers. Hum. Gene Ther. 7:2123-2133 (1996).
    • (1996) Hum. Gene Ther. , vol.7 , pp. 2123-2133
    • Wolfert, M.A.1    Schacht, E.H.2    Toncheva, V.3    Ulbrich, K.4    Nazarova, O.5    Seymour, L.W.6
  • 15
    • 0031239718 scopus 로고    scopus 로고
    • Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer
    • S. Katayose and K. Kataoka. Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer. Bioconjug. Chem. 8:702-707 (1997).
    • (1997) Bioconjug. Chem. , vol.8 , pp. 702-707
    • Katayose, S.1    Kataoka, K.2
  • 16
    • 0031938986 scopus 로고    scopus 로고
    • Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer
    • S. Katayose and K. Kataoka. Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer. J. Pharm. Sci. 87:160-163 (1998).
    • (1998) J. Pharm. Sci. , vol.87 , pp. 160-163
    • Katayose, S.1    Kataoka, K.2
  • 17
    • 0035080570 scopus 로고    scopus 로고
    • Physicochemical properties and nuclease resistance of antisense-oligodeoxynucleotides entrapped in the core of polyion complex micelles composed of poly(ethylene glycol)-poly(L-lysine) block copolymers
    • A. Harada, H. Togawa, and K. Kataoka. Physicochemical properties and nuclease resistance of antisense-oligodeoxynucleotides entrapped in the core of polyion complex micelles composed of poly(ethylene glycol)-poly(L-lysine) block copolymers. Eur. J. Pharm. Sci. 13:35-42 (2001).
    • (2001) Eur. J. Pharm. Sci. , vol.13 , pp. 35-42
    • Harada, A.1    Togawa, H.2    Kataoka, K.3
  • 18
    • 85047695467 scopus 로고    scopus 로고
    • Polyion complex micelles as vectors in gene therapy-pharmacokinetics and in vivo gene transfer
    • M. Harada-Shiba, K. Yamauchi, A. Harada, I. Takamisawa, K. Shimokado, and K. Kataoka. Polyion complex micelles as vectors in gene therapy- pharmacokinetics and in vivo gene transfer. Gene Ther. 9:407-414 (2002).
    • (2002) Gene Ther. , vol.9 , pp. 407-414
    • Harada-Shiba, M.1    Yamauchi, K.2    Harada, A.3    Takamisawa, I.4    Shimokado, K.5    Kataoka, K.6
  • 19
    • 0002863889 scopus 로고    scopus 로고
    • Poly-(ethylene glycol)-block-poly(L-lysine) dendrimer: Novel linear polymer/dendrimer block copolymer forming a spherical water-soluble polyionic complex with DNA
    • J. S. Choi, E. J. Lee, Y. H. Choi, Y. J. Jeong, and J. S. Park. Poly-(ethylene glycol)-block-poly(L-lysine) dendrimer: novel linear polymer/dendrimer block copolymer forming a spherical water-soluble polyionic complex with DNA. Bioconjug. Chem. 10:62-65 (1999).
    • (1999) Bioconjug. Chem. , vol.10 , pp. 62-65
    • Choi, J.S.1    Lee, E.J.2    Choi, Y.H.3    Jeong, Y.J.4    Park, J.S.5
  • 20
    • 0001703760 scopus 로고    scopus 로고
    • Synthesis of a barbell-like triblock, poly(L-lysine) dendrimer-block- poly-(ethylene glycol)-block-poly(L-lysine) dendrimer, and its self-assembly with plasmid DNA
    • J. S. Choi, D. K. Joo, C. H. Kim, K. Kim, and J. S. Park. Synthesis of a barbell-like triblock, poly(L-lysine) dendrimer-block-poly-(ethylene glycol)-block-poly(L-lysine) dendrimer, and its self-assembly with plasmid DNA. J. Am. Chem. Soc. 122:474-480 (2000).
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 474-480
    • Choi, J.S.1    Joo, D.K.2    Kim, C.H.3    Kim, K.4    Park, J.S.5
  • 21
    • 1642588217 scopus 로고    scopus 로고
    • Biodegradable poly(ethylene glycol)-co-poly(L-lysine)-g-histidine multiblock copolymers for nonviral gene delivery
    • M. Bikram, C. H. Ahn, S. Y. Chae, M. Lee, J. W. Yockman, and S. W. Kim. Biodegradable poly(ethylene glycol)-co-poly(L-lysine)-g-histidine multiblock copolymers for nonviral gene delivery. Macromolecules 37:1903-1916 (2004).
    • (2004) Macromolecules , vol.37 , pp. 1903-1916
    • Bikram, M.1    Ahn, C.H.2    Chae, S.Y.3    Lee, M.4    Yockman, J.W.5    Kim, S.W.6
  • 22
    • 0002656438 scopus 로고    scopus 로고
    • Polyethylene glycol-grafted poly-L-lysine as polymeric gene carrier
    • Y. H. Choi, F. Liu, J. S. Kim, Y. K. Choi, J. S. Park, and S. W. Kim. Polyethylene glycol-grafted poly-L-lysine as polymeric gene carrier. J. Control. Rel. 54:39-48 (1998).
    • (1998) J. Control. Rel. , vol.54 , pp. 39-48
    • Choi, Y.H.1    Liu, F.2    Kim, J.S.3    Choi, Y.K.4    Park, J.S.5    Kim, S.W.6
  • 23
    • 0034761853 scopus 로고    scopus 로고
    • Repression of GAD autoantigen expression in pancreas beta-Cells by delivery of antisense plasmid/PEG-g-PLL complex
    • M. Lee, S. O. Han, K. S. Ko, J. J. Koh, J. S. Park, J. W. Yoon, and S. W. Kim. Repression of GAD autoantigen expression in pancreas beta-Cells by delivery of antisense plasmid/PEG-g-PLL complex. Mol. Ther. 4:339-346 (2001).
    • (2001) Mol. Ther. , vol.4 , pp. 339-346
    • Lee, M.1    Han, S.O.2    Ko, K.S.3    Koh, J.J.4    Park, J.S.5    Yoon, J.W.6    Kim, S.W.7
  • 25
    • 0032496287 scopus 로고    scopus 로고
    • Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers
    • V. Toncheva, M. A. Wolfert, P. R. Dash, D. Oupicky, K. Ulbrich, L. W. Seymour, and E. H. Schacht. Novel vectors for gene delivery formed by self-assembly of DNA with poly(L-lysine) grafted with hydrophilic polymers. Biochim. Biophys. Acta 1380:354-368 (1998).
    • (1998) Biochim. Biophys. Acta , vol.1380 , pp. 354-368
    • Toncheva, V.1    Wolfert, M.A.2    Dash, P.R.3    Oupicky, D.4    Ulbrich, K.5    Seymour, L.W.6    Schacht, E.H.7
  • 27
    • 0030462391 scopus 로고    scopus 로고
    • Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold
    • O. Boussif, M. A. Zanta, and J. P. Behr. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther. 3:1074-1080 (1996).
    • (1996) Gene Ther. , vol.3 , pp. 1074-1080
    • Boussif, O.1    Zanta, M.A.2    Behr, J.P.3
  • 28
    • 0030757526 scopus 로고    scopus 로고
    • Nanoscopic structure of DNA condensed for gene delivery
    • D. D. Dunlap, A. Maggi, M. R. Soria, and L. Monaco. Nanoscopic structure of DNA condensed for gene delivery. Nucleic Acids Res. 25:3095-3101 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 3095-3101
    • Dunlap, D.D.1    Maggi, A.2    Soria, M.R.3    Monaco, L.4
  • 29
    • 0032811354 scopus 로고    scopus 로고
    • Poly(ethylenimine) and its role in gene delivery
    • W. T. Godbey, K. K. Wu, and A. G. Mikos. Poly(ethylenimine) and its role in gene delivery. J. Control. Rel. 60:149-160 (1999).
    • (1999) J. Control. Rel. , vol.60 , pp. 149-160
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 30
    • 0036077937 scopus 로고    scopus 로고
    • Polyethylenimine-graft-poly(ethylene glycol) copolymers: Influence of copolymer block structure on DNA complexation and biological activities as gene delivery system
    • H. Petersen, P. M. Fechner, A. L. Martin, K. Kunath, S. Stolnik, C. J. Roberts, D. Fischer, M. C. Davies, and T. Kissel. Polyethylenimine-graft- poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. Bioconjug. Chem. 13:845-854 (2002).
    • (2002) Bioconjug. Chem. , vol.13 , pp. 845-854
    • Petersen, H.1    Fechner, P.M.2    Martin, A.L.3    Kunath, K.4    Stolnik, S.5    Roberts, C.J.6    Fischer, D.7    Davies, M.C.8    Kissel, T.9
  • 31
    • 0041808905 scopus 로고    scopus 로고
    • Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cord
    • L. Shi, G. P. Tang, S. J. Gao, Y. X. Ma, B. H. Liu, Y. Li, J. M. Zeng, Y. K. Ng, K. W. Leong, and S. Wang. Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cord. Gene Ther. 10:1179-1188 (2003).
    • (2003) Gene Ther. , vol.10 , pp. 1179-1188
    • Shi, L.1    Tang, G.P.2    Gao, S.J.3    Ma, Y.X.4    Liu, B.H.5    Li, Y.6    Zeng, J.M.7    Ng, Y.K.8    Leong, K.W.9    Wang, S.10
  • 32
    • 0036737813 scopus 로고    scopus 로고
    • Star-shaped poly(ethylene glycol)block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines
    • H. Petersen, K. Kunath, A. L. Martin, S. Stolnik, C. J. Roberts, M. C. Davies, and T. Kissel. Star-shaped poly(ethylene glycol)block-polyethylenimine copolymers enhance DNA condensation of low molecular weight polyethylenimines. Biomacromolecules 3:926-936 (2002).
    • (2002) Biomacromolecules , vol.3 , pp. 926-936
    • Petersen, H.1    Kunath, K.2    Martin, A.L.3    Stolnik, S.4    Roberts, C.J.5    Davies, M.C.6    Kissel, T.7
  • 34
    • 0037161323 scopus 로고    scopus 로고
    • Biodegradable poly(ethylenimine) for plasmid DNA delivery
    • C. H. Ahn, S. Y. Chae, Y. H. Bae, and S. W. Kim. Biodegradable poly(ethylenimine) for plasmid DNA delivery. J. Control. Rel. 80:273-282 (2002).
    • (2002) J. Control. Rel. , vol.80 , pp. 273-282
    • Ahn, C.H.1    Chae, S.Y.2    Bae, Y.H.3    Kim, S.W.4
  • 38
    • 0036225362 scopus 로고    scopus 로고
    • Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation
    • D. Oupicky, M. Ogris, K. A. Howard, P. R. Dash, K. Ulbrich, and L. W. Seymour. Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation. Mol. Ther. 5:463-472 (2002).
    • (2002) Mol. Ther. , vol.5 , pp. 463-472
    • Oupicky, D.1    Ogris, M.2    Howard, K.A.3    Dash, P.R.4    Ulbrich, K.5    Seymour, L.W.6
  • 39
    • 0036853181 scopus 로고    scopus 로고
    • An angiogenic, endothelial-cell-targeted polymeric gene carrier
    • W. Suh, S. O. Han, L. Yu, and S. W. Kim. An angiogenic, endothelial-cell-targeted polymeric gene carrier. Mol. Ther. 6:664-672 (2002).
    • (2002) Mol. Ther. , vol.6 , pp. 664-672
    • Suh, W.1    Han, S.O.2    Yu, L.3    Kim, S.W.4
  • 40
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • P. C. Brooks, R. A. Clark, and D. A. Cheresh. Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science 264:569-571 (1994).
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 41
    • 0031862889 scopus 로고    scopus 로고
    • Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging
    • D. A. Sipkins, D. A. Cheresh, M. R. Kazemi, L. M. Nevin, M. D. Bednarski, and K. C. Li. Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. Nat. Med. 4:623-626 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 623-626
    • Sipkins, D.A.1    Cheresh, D.A.2    Kazemi, M.R.3    Nevin, L.M.4    Bednarski, M.D.5    Li, K.C.6
  • 43
    • 0033960562 scopus 로고    scopus 로고
    • Integrins alpha(v)beta3 and alpha(v)beta5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide
    • A. Erdreich-Epstein, H. Shimada, S. Groshen, M. Liu, L. S. Metelitsa, K. S. Kim, M. F. Stins, R. C. Seeger, and D. L. Durden. Integrins alpha(v)beta3 and alpha(v)beta5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide. Cancer Res. 60: 712-721 (2000).
    • (2000) Cancer Res. , vol.60 , pp. 712-721
    • Erdreich-Epstein, A.1    Shimada, H.2    Groshen, S.3    Liu, M.4    Metelitsa, L.S.5    Kim, K.S.6    Stins, M.F.7    Seeger, R.C.8    Durden, D.L.9
  • 44
    • 0141715047 scopus 로고    scopus 로고
    • Integrin targeting using RGD-PEI conjugates for in vitro gene transfer
    • K. Kunath, T. Merdan, O. Hegener, H. Haberlein, and T. Kissel. Integrin targeting using RGD-PEI conjugates for in vitro gene transfer. J. Gene Med. 5:588-599 (2003).
    • (2003) J. Gene Med. , vol.5 , pp. 588-599
    • Kunath, K.1    Merdan, T.2    Hegener, O.3    Haberlein, H.4    Kissel, T.5
  • 46
    • 0032580535 scopus 로고    scopus 로고
    • Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine)
    • M. Hashida, S. Takemura, M. Nishikawa, and Y. Takakura. Targeted delivery of plasmid DNA complexed with galactosylated poly(L-lysine). J. Control. Rel. 53:301-310 (1998).
    • (1998) J. Control. Rel. , vol.53 , pp. 301-310
    • Hashida, M.1    Takemura, S.2    Nishikawa, M.3    Takakura, Y.4
  • 47
    • 0032453959 scopus 로고    scopus 로고
    • Targeted delivery of plasmid DNA to hepatocytes in vivo: Optimization of the pharmacokinetics of plasmid DNA/galactosylated poly(L-lysine) complexes by controlling their physicochemical properties
    • M. Nishikawa, S. Takemura, Y. Takakura, and M. Hashida. Targeted delivery of plasmid DNA to hepatocytes in vivo: optimization of the pharmacokinetics of plasmid DNA/galactosylated poly(L-lysine) complexes by controlling their physicochemical properties. J. Pharmacol. Exp. Ther. 287:408-415 (1998).
    • (1998) J. Pharmacol. Exp. Ther. , vol.287 , pp. 408-415
    • Nishikawa, M.1    Takemura, S.2    Takakura, Y.3    Hashida, M.4
  • 48
    • 0030907837 scopus 로고    scopus 로고
    • Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine)
    • R. I. Mahato, S. Takemura, K. Akamatsu, M. Nishikawa, Y. Takakura, and M. Hashida. Physicochemical and disposition characteristics of antisense oligonucleotides complexed with glycosylated poly(L-lysine). Biochem. Pharmacol. 53:887-895 (1997).
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 887-895
    • Mahato, R.I.1    Takemura, S.2    Akamatsu, K.3    Nishikawa, M.4    Takakura, Y.5    Hashida, M.6
  • 49
    • 0001121655 scopus 로고    scopus 로고
    • Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-targeted gene carrier
    • Y. H. Choi, F. Liu, J. S. Park, and S. W. Kim. Lactose-poly(ethylene glycol)-grafted poly-L-lysine as hepatoma cell-targeted gene carrier. Bioconjug. Chem. 9:708-718 (1998).
    • (1998) Bioconjug. Chem. , vol.9 , pp. 708-718
    • Choi, Y.H.1    Liu, F.2    Park, J.S.3    Kim, S.W.4
  • 50
    • 0001451822 scopus 로고    scopus 로고
    • Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine and its complex with plasmid DNA
    • Y. H. Choi, F. Liu, J. S. Choi, S. W. Kim, and J. S. Park. Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine and its complex with plasmid DNA. Hum. Gene Ther. 10:2657-2665 (1999).
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2657-2665
    • Choi, Y.H.1    Liu, F.2    Choi, J.S.3    Kim, S.W.4    Park, J.S.5
  • 51
    • 0033167367 scopus 로고    scopus 로고
    • Size reduction of galactosylated PEI/DNA complexes improves lectin-mediated gene transfer into hepatocytes
    • T. Bettinger, J. S. Remy, and P. Erbacher. Size reduction of galactosylated PEI/DNA complexes improves lectin-mediated gene transfer into hepatocytes. Bioconjug. Chem. 10:558-561 (1999).
    • (1999) Bioconjug. Chem. , vol.10 , pp. 558-561
    • Bettinger, T.1    Remy, J.S.2    Erbacher, P.3
  • 52
    • 0037133104 scopus 로고    scopus 로고
    • A new synthesis of galactose-poly(ethylene glycol)-polyethylenimine for gene delivery to hepatocytes
    • K. Sagara and S. W. Kim. A new synthesis of galactose-poly(ethylene glycol)-polyethylenimine for gene delivery to hepatocytes. J. Control. Rel. 79:271-281 (2002).
    • (2002) J. Control. Rel. , vol.79 , pp. 271-281
    • Sagara, K.1    Kim, S.W.2
  • 53
    • 0031743112 scopus 로고    scopus 로고
    • Receptor and non-receptor mediated uptake of chylomicron remnants by the liver
    • R. J. Havel. Receptor and non-receptor mediated uptake of chylomicron remnants by the liver. Atherosclerosis 141:S1-S7 (1998).
    • (1998) Atherosclerosis , vol.141
    • Havel, R.J.1
  • 54
    • 0025139218 scopus 로고
    • Focal accumulation of an apolipoprotein B-based synthetic oligopeptide in the healing rabbit arterial wall
    • I. L. Shih, R. S. Lees, M. Y. Chang, and A. M. Lees. Focal accumulation of an apolipoprotein B-based synthetic oligopeptide in the healing rabbit arterial wall. Proc. Natl. Acad. Sci. USA 87: 1436-1440 (1990).
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1436-1440
    • Shih, I.L.1    Lees, R.S.2    Chang, M.Y.3    Lees, A.M.4
  • 55
    • 0032800011 scopus 로고    scopus 로고
    • Uptake of oxidized LDL by macrophages differs from that of acetyl LDL and leads to expansion of an acidic endolysosomal compartment
    • M. Lougheed, E. D. Moore, D. R. Scriven, and U. P. Steinbrecher. Uptake of oxidized LDL by macrophages differs from that of acetyl LDL and leads to expansion of an acidic endolysosomal compartment. Arterioscler. Thromb. Vasc. Biol. 19:1881-1890 (1999).
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 1881-1890
    • Lougheed, M.1    Moore, E.D.2    Scriven, D.R.3    Steinbrecher, U.P.4
  • 56
    • 0037122694 scopus 로고    scopus 로고
    • Artery wall binding peptide-poly(ethylene glycol)-grafted-poly(L-lysine)- based gene delivery to artery wall cells
    • J. W. Nah, L. Yu, S. O. Han, C. H. Ahn, and S. W. Kim. Artery wall binding peptide-poly(ethylene glycol)-grafted-poly(L-lysine)-based gene delivery to artery wall cells. J. Control. Rel. 78:273-284 (2002).
    • (2002) J. Control. Rel. , vol.78 , pp. 273-284
    • Nah, J.W.1    Yu, L.2    Han, S.O.3    Ahn, C.H.4    Kim, S.W.5
  • 57
    • 0027436790 scopus 로고
    • Endocytosis of folate-protein conjugates: Ultrastructural localization in KB cells
    • J. J. Turek, C. P. Leamon, and P. S. Low. Endocytosis of folate-protein conjugates: ultrastructural localization in KB cells. J. Cell Sci. 106:423-430 (1993).
    • (1993) J. Cell Sci. , vol.106 , pp. 423-430
    • Turek, J.J.1    Leamon, C.P.2    Low, P.S.3
  • 58
    • 0032580526 scopus 로고    scopus 로고
    • Folate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cells
    • S. Wang and P. S. Low. Folate-mediated targeting of antineoplastic drugs, imaging agents, and nucleic acids to cancer cells. J. Control. Rel. 53:39-48 (1998).
    • (1998) J. Control. Rel. , vol.53 , pp. 39-48
    • Wang, S.1    Low, P.S.2
  • 59
    • 0029360588 scopus 로고
    • Transfection of folate-polylysine DNA complexes: Evidence for lysosomal delivery
    • K. A. Mislick, J. D. Baldeschwieler, J. F. Kayyem, and T. J. Meade. Transfection of folate-polylysine DNA complexes: evidence for lysosomal delivery. Bioconjug. Chem. 6:512-515 (1995).
    • (1995) Bioconjug. Chem. , vol.6 , pp. 512-515
    • Mislick, K.A.1    Baldeschwieler, J.D.2    Kayyem, J.F.3    Meade, T.J.4
  • 60
    • 0036730299 scopus 로고    scopus 로고
    • Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo
    • C. M. Ward, M. Pechar, D. Oupicky, K. Ulbrich, and L. W. Seymour. Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo. J. Gene Med. 4:536-547 (2002).
    • (2002) J. Gene Med. , vol.4 , pp. 536-547
    • Ward, C.M.1    Pechar, M.2    Oupicky, D.3    Ulbrich, K.4    Seymour, L.W.5
  • 61
    • 0033230555 scopus 로고    scopus 로고
    • Folate copolymer-mediated transfection of cultured cells
    • C. P. Leamon, D. Weigl, and R. W. Hendren. Folate copolymer-mediated transfection of cultured cells. Bioconjug. Chem. 10:947-957 (1999).
    • (1999) Bioconjug. Chem. , vol.10 , pp. 947-957
    • Leamon, C.P.1    Weigl, D.2    Hendren, R.W.3
  • 63
    • 0037133088 scopus 로고    scopus 로고
    • Optimization of factors influencing the transfection efficiency of folate-PEG-folate-graft-polyethylenimine
    • J. M. Benns, R. I. Mahato, and S. W. Kim. Optimization of factors influencing the transfection efficiency of folate-PEG-folate-graft- polyethylenimine. J. Control. Rel. 79:255-269 (2002).
    • (2002) J. Control. Rel. , vol.79 , pp. 255-269
    • Benns, J.M.1    Mahato, R.I.2    Kim, S.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.