DNA sequences in cationic lipid:pDNA-mediated systemic toxicities

Human Gene Therapy

Volumn 14, Issue 3, 2003, Pages 203-214

  Tousignant, Jennifer D ^a   Zhao, Hongmei ^a   Yew, Nelson S ^a   Cheng, Seng H ^a   Eastman, Simon J ^a   Scheule, Ronald K ^a  

^a GENZYME CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; CATIONIC LIPID; CYTOKINE; DNA; GAMMA INTERFERON; INTERLEUKIN 12; LIPID; PLASMID DNA; SPERMINE CHOLESTERYLCARBAMATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATIONIC LIPID PLASMID DNA COMPLEX; CATIONIC LIPID PLASMID DNA DELIVERY SYSTEM; COMPLEX FORMATION; CONTROLLED STUDY; CPG ISLAND; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; DNA SEQUENCE; DNA STRUCTURE; DOSE RESPONSE; ENZYME BLOOD LEVEL; FEMALE; GENE DELIVERY SYSTEM; GENE TRANSFER; GENETIC TRANSFECTION; IMMUNOSTIMULATION; LEUKOPENIA; MAXIMUM TOLERATED DOSE; METHYLATION; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; STATISTICAL SIGNIFICANCE; STRUCTURE ANALYSIS; SYSTEMIC DISEASE; THROMBOCYTOPENIA; TOXICITY TESTING;

ANIMALS; CPG ISLANDS; CYTOKINES; DNA; DNA METHYLATION; INTERLEUKIN-12; LIPID METABOLISM; LIPIDS; MICE; MICE, INBRED BALB C;

ANIMALIA;

EID: 0037429045     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430340360535760     Document Type: Article

References (23)

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