Polyethylenimine with acid-labile linkages as a biodegradable gene carrier

Journal of Controlled Release

Volumn 103, Issue 1, 2005, Pages 209-219

  Kim, Young Heui ^a   Park, Jeong Hyun ^a,b   Lee, Minhyung ^c   Kim, Yong Hee ^a   Park, Tae Gwan ^d   Kim, Sung Wan ^a  

^a UNIVERSITY OF UTAH   (United States)

^b Inje University College of Medicine   (South Korea)

^c Inha University School of Medicine   (South Korea)

^d Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Acid labile polymer; Cytotoxicity; Gene delivery; Polyethylenimine (PEI); Transfection

Indexed keywords

BIOASSAY; BIODEGRADATION; DNA; GENES; MOLECULAR WEIGHT; PH EFFECTS; SYNTHESIS (CHEMICAL); TOXICITY;

CYTOTOXICITY; PLASMID DNA (PDNA); POLYETHYLENIMINE (PEI); TRANSFECTION EFFICIENCY;

ORGANIC POLYMERS;

ALDEHYDE DERIVATIVE; GLUTADIALDEHYDE; NITROGEN DERIVATIVE; PHOSPHATE; PLASMID DNA; POLYETHYLENEIMINE; UNCLASSIFIED DRUG;

ACIDITY; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; ASSAY; BIODEGRADABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DEGRADATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG SYNTHESIS; EMBRYO; ENDOSOME; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR WEIGHT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; RAT; TOXICITY TESTING; ZETA POTENTIAL;

ACIDS; BIOTRANSFORMATION; CELL LINE; DRUG CARRIERS; GENE THERAPY; HUMANS; POLYETHYLENEIMINE; TRANSFECTION;

EID: 13844269030     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.11.008     Document Type: Article

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