Sequential injection of cationic liposome and plasmid DNA effectively transfects the lung with minimal inflammatory toxicity

Molecular Therapy

Volumn 3, Issue 5, 2001, Pages 673-682

  Tan, Yadi ^a   Liu, Feng ^a   Li, Zhiyu ^a   Li, Song ^a   Huang, Leaf ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Cationic liposome; Cytokine induction; Gene transfer; Inflammatory toxicity; Lipoplex; Plasmid DNA; Sequential injection; Systemic

Indexed keywords

CATION; COMPLEMENT; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; GAMMA INTERFERON; INTERLEUKIN 12; LIPOSOME; PLASMID DNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; CYTOKINE RELEASE; DNA VECTOR; DRUG FORMULATION; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; IMMUNE RESPONSE; INFLAMMATION; LUNG; LYMPHOCYTOPENIA; MOUSE; NEUTROPENIA; NONHUMAN; THROMBOCYTOPENIA; TRANSGENE;

ANIMALIA;

EID: 0034991899     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.2001.0311     Document Type: Article

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