SCOPUS 정보 검색 플랫폼

ChemMedChem

Volumn 1, Issue 8, 2006, Pages 760-782

The 7TM G-protein-coupled receptor target family

(4) Jacoby, Edgar a Bouhelal, Rochdi a Gerspacher, Marc a Seuwen, Klaus a

a NOVARTIS PHARMA AG (Switzerland)

Author keywords

Chemical biology; Expression analysis; High throughput screening; Library design; Structural biology

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LIGAND; SEVEN TRANSMEMBRANE G PROTEIN COUPLED RECEPTOR; SEVEN-TRANSMEMBRANE G-PROTEIN-COUPLED RECEPTOR;

ANIMAL; COMBINATORIAL CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG POTENTIATION; GENE EXPRESSION PROFILING; HISTORY; HUMAN; MOUSE; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; GENE EXPRESSION PROFILING; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; LIGANDS; MICE; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748671369 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200600134 Document Type: Review

Times cited : (302)

References (126)

1
- 0036717194
- A. L. Hopkins, C. R. Groom, Nat. Rev. Drug Discovery 2002, 1, 727-730.
- (2002) Nat. Rev. Drug Discovery , vol.1 , pp. 727-730
- Hopkins, A.L.¹ Groom, C.R.²

2
- 0037020329
- T. Klabunde, G. Hessler, ChemBioChem 2002, 3, 928-944.
- (2002) ChemBioChem , vol.3 , pp. 928-944
- Klabunde, T.¹ Hessler, G.²

3
- 2442700768
- (Eds.: J. C. Foreman, T. Johansen), CRC, Washington, DC
- T. W. Schwartz, B. Holst in Textbook of Receptor Pharmacology (Eds.: J. C. Foreman, T. Johansen), CRC, Washington, DC, 2003, pp. 81-109.
- (2003) Textbook of Receptor Pharmacology , pp. 81-109
- Schwartz, T.W.¹ Holst, B.²

4
- 23744486171
- C. Ellis, Nat. Rev. Drug Discovery 2004, 3, 577-626.
- (2004) Nat. Rev. Drug Discovery , vol.3 , pp. 577-626
- Ellis, C.¹

5
- 33748636343
- H. C. Huang, P. S. Klein, Adv. Genome Biol. 2004, 5, 234.1-234.7.
- (2004) Adv. Genome Biol. , vol.5
- Huang, H.C.¹ Klein, P.S.²

6
- 0037252680
- F. Horn, E. Bettler, L. Oliveira, F. Campagne, F. E. Cohen, G. Vriend, Nucleic Acids Res. 2003, 31, 294-297.
- (2003) Nucleic Acids Res. , vol.31 , pp. 294-297
- Horn, F.¹ Bettler, E.² Oliveira, L.³ Campagne, F.⁴ Cohen, F.E.⁵ Vriend, G.⁶

7
- 16244383540
- S. R. J. Hoare, Drug Discovery Today 2005, 10, 417-427.
- (2005) Drug Discovery Today , vol.10 , pp. 417-427
- Hoare, S.R.J.¹

8
- 0038662595
- J. P. Pin, T. Galvez, L. Prezeau, Pharmacol. Ther. 2003, 98, 325-354.
- (2003) Pharmacol. Ther. , vol.98 , pp. 325-354
- Pin, J.P.¹ Galvez, T.² Prezeau, L.³

9
- 0038024615
- R. Fredriksson, M. C. Lagerström, L. G. Lundin, H. B. Schiöth, Mol. Pharmacol. 2003, 63, 1256-1272.
- (2003) Mol. Pharmacol. , vol.63 , pp. 1256-1272
- Fredriksson, R.¹ Lagerström, M.C.² Lundin, L.G.³ Schiöth, H.B.⁴

10
- 0004230642
- IUPHAR Media
- IUPHAR Committee on Receptor Nomenclature and Drug Classification, The IUPHAR Compendium of Receptor Characterization and Classification, 2nd ed., 2000, IUPHAR Media.
- (2000) The IUPHAR Compendium of Receptor Characterization and Classification, 2nd Ed.

11
- 19944370732
- (Eds.: H. Kubinyi, G. Müller), Wiley-VCH, Weinheim
- E. Jacoby, A. Schuffenhauer, P. Acklin in Chemogenomics in Drug Discovery-A Medicinal Chemistry Perspective (Eds.: H. Kubinyi, G. Müller), Wiley-VCH, Weinheim, 2004, pp. 139-166.
- (2004) Chemogenomics in Drug Discovery - A Medicinal Chemistry Perspective , pp. 139-166
- Jacoby, E.¹ Schuffenhauer, A.² Acklin, P.³

12
- 0037092610
- G. Wess, Drug Discovery Today 2002, 4, 533-535.
- (2002) Drug Discovery Today , vol.4 , pp. 533-535
- Wess, G.¹

13
- 3242793327
- R. Lefkowitz, Trends Pharmacol. Sci. 2004, 25, 413-422.
- (2004) Trends Pharmacol. Sci. , vol.25 , pp. 413-422
- Lefkowitz, R.¹

14
- 0345490945
- R. R. Neubig, M. Spedding, T. Kenakin, A. Christopoulos, Pharmacol. Rev. 2003, 55, 597-606.
- (2003) Pharmacol. Rev. , vol.55 , pp. 597-606
- Neubig, R.R.¹ Spedding, M.² Kenakin, T.³ Christopoulos, A.⁴

15
- 0029320699
- M. Rodbell, Biosci. Rep. 1995, 15, 117-133.
- (1995) Biosci. Rep. , vol.15 , pp. 117-133
- Rodbell, M.¹

16
- 0029282131
- A. G. Gilman, Biosci. Rep. 1995, 15, 65-97.
- (1995) Biosci. Rep. , vol.15 , pp. 65-97
- Gilman, A.G.¹

17
- 0015493877
- E. W. Sutherland, Science 1972, 177, 401-408.
- (1972) Science , vol.177 , pp. 401-408
- Sutherland, E.W.¹

18
- 0035398487
- M. J. Marinissen, J. S. Gutkind, Trends Pharmacol. Sci. 2001, 22, 368-376.
- (2001) Trends Pharmacol. Sci. , vol.22 , pp. 368-376
- Marinissen, M.J.¹ Gutkind, J.S.²

19
- 0031984517
- H. Hamm, J. Biol. Chem. 1998, 273, 669-672.
- (1998) J. Biol. Chem. , vol.273 , pp. 669-672
- Hamm, H.¹

20
- 0024360756
- J. Black, In Vitro Cell. Dev. Biol. 1989, 25, 311-320.
- (1989) In Vitro Cell. Dev. Biol. , vol.25 , pp. 311-320
- Black, J.¹

21
- 0018770017
- M. G. Caron, Y. Srinivasan, J. Pitha, K. Kociolek, R. J. Lefkowitz, J. Biol. Chem. 1979, 254, 2923-2927.
- (1979) J. Biol. Chem. , vol.254 , pp. 2923-2927
- Caron, M.G.¹ Srinivasan, Y.² Pitha, J.³ Kociolek, K.⁴ Lefkowitz, R.J.⁵

22
- 0020503940
- R. A. Cerione, B. Strulovici, J. L. Benovic, C. D. Strader, M. G. Caron, R. J. Lefkowitz, Proc. Natl. Acad. Sci. USA 1983, 80, 4899-4903.
- (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4899-4903
- Cerione, R.A.¹ Strulovici, B.² Benovic, J.L.³ Strader, C.D.⁴ Caron, M.G.⁵ Lefkowitz, R.J.⁶

23
- 0022485749
- R. A. F. Dixon, B. K. Kobilka, D. J. Strader, J. L. Benovic, H. G. Dohlman, T. Frielle, M. A. Bolanowski, C. D. Bennett, E. Rands, R. E. Diehl, R. A. Mumford, E. E. Slater, I. S. Sigal, M. G. Caron, R. J. Lefkowitz, C. D. Strader, Nature 1986, 321, 75-79.
- (1986) Nature , vol.321 , pp. 75-79
- Dixon, R.A.F.¹ Kobilka, B.K.² Strader, D.J.³ Benovic, J.L.⁴ Dohlman, H.G.⁵ Frielle, T.⁶ Bolanowski, M.A.⁷ Bennett, C.D.⁸ Rands, E.⁹ Diehl, R.E.¹⁰ Mumford, R.A.¹¹ Slater, E.E.¹² Sigal, I.S.¹³ Caron, M.G.¹⁴ Lefkowitz, R.J.¹⁵ Strader, C.D.¹⁶

24
- 0023355931
- Y. A. Ovchinnikov, Photochem. Photobiol. 1987, 45, 909-914.
- (1987) Photochem. Photobiol. , vol.45 , pp. 909-914
- Ovchinnikov, Y.A.¹

25
- 0016842810
- R. Henderson, P. N. Unwin, Nature 1975, 257, 28-32.
- (1975) Nature , vol.257 , pp. 28-32
- Henderson, R.¹ Unwin, P.N.²

26
- 0037385656
- N. Robas, M. O'Reilly, S. Katugampola, M. Fidock, Curr. Opin. Pharmacol. 2003, 3, 121-126.
- (2003) Curr. Opin. Pharmacol. , vol.3 , pp. 121-126
- Robas, N.¹ O'Reilly, M.² Katugampola, S.³ Fidock, M.⁴

27
- 1342281272
- A. Wise, S. C. Jupe, S. Rees, Annu. Rev. Pharmacol. Toxicol. 2004, 44, 43-66.
- (2004) Annu. Rev. Pharmacol. Toxicol. , vol.44 , pp. 43-66
- Wise, A.¹ Jupe, S.C.² Rees, S.³

28
- 0036033424
- R. Seifert, K. Wenzel-Seifert, Naunyn-Schmiedeberg's Arch. Pharmacol. 2002, 366, 381-416.
- (2002) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.366 , pp. 381-416
- Seifert, R.¹ Wenzel-Seifert, K.²

29
- 0028943780
- E. Schipani, K. Kruse, H. Juppner, Science 1995, 268, 98-100.
- (1995) Science , vol.268 , pp. 98-100
- Schipani, E.¹ Kruse, K.² Juppner, H.³

30
- 0036468505
- P. Strange, Trends Pharmacol. Sci. 2002, 23, 89-95.
- (2002) Trends Pharmacol. Sci. , vol.23 , pp. 89-95
- Strange, P.¹

31
- 0023263617
- C. D. Strader, I. S. Sigal, R. B. Register, M. R. Candelore, E. Rands, R. A. Dixon, Proc. Natl. Acad. Sci. USA 1987, 84, 4384-4388.
- (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 4384-4388
- Strader, C.D.¹ Sigal, I.S.² Register, R.B.³ Candelore, M.R.⁴ Rands, E.⁵ Dixon, R.A.⁶

32
- 0029919840
- A. M. van Rhee, K. A. Jacobson, Drug Dev. Res. 1996, 37, 1-38.
- (1996) Drug Dev. Res. , vol.37 , pp. 1-38
- Van Rhee, A.M.¹ Jacobson, K.A.²

33
- 0037862083
- J. Bockaert, P. Marin, A. Dumuis, L. Fagni, FEBS Lett. 2003, 546, 65-72.
- (2003) FEBS Lett. , vol.546 , pp. 65-72
- Bockaert, J.¹ Marin, P.² Dumuis, A.³ Fagni, L.⁴

34
- 0033118334
- J. Bockaert, J. P. Pin, EMBO J. 1999, 18, 1723-1729.
- (1999) EMBO J. , vol.18 , pp. 1723-1729
- Bockaert, J.¹ Pin, J.P.²

35
- 4944256731
- J. Bockaert, A. Dumuis, L. Fagni, P. Marin, Curr. Opin. Drug Discovery Dev. 2004, 7, 649-657.
- (2004) Curr. Opin. Drug Discovery Dev. , vol.7 , pp. 649-657
- Bockaert, J.¹ Dumuis, A.² Fagni, L.³ Marin, P.⁴

36
- 0037446894
- D. K. Vassilatis, J. G. Hohmann, H. Zeng, F. Li, J. E. Ranchalis, M. T. Mortrud, A. Brown, S. S. Rodriguez, J. R. Weller, A. C. Wright, J. E. Bergmann, G. A. Gaitanaris, Proc. Natl. Acad. Sci. USA 2003, 100, 4903-4908.
- (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4903-4908
- Vassilatis, D.K.¹ Hohmann, J.G.² Zeng, H.³ Li, F.⁴ Ranchalis, J.E.⁵ Mortrud, M.T.⁶ Brown, A.⁷ Rodriguez, S.S.⁸ Weller, J.R.⁹ Wright, A.C.¹⁰ Bergmann, J.E.¹¹ Gaitanaris, G.A.¹²

37
- 0025825726
- L. Buck, R. Axel, Cell 1991, 65, 175-187.
- (1991) Cell , vol.65 , pp. 175-187
- Buck, L.¹ Axel, R.²

38
- 85010068593
- A. Terakita, Adv. Genome Biol. 2005, 6, 213.1-213.9.
- (2005) Adv. Genome Biol. , vol.6
- Terakita, A.¹

39
- 17844400914
- R. Fredriksson, H. B. Schiöth, Mol. Pharmacol. 2005, 67, 1414-1425.
- (2005) Mol. Pharmacol. , vol.67 , pp. 1414-1425
- Fredriksson, R.¹ Schiöth, H.B.²

40
- 10044254636
- A. Sodhi, S. Montaner, J. E. Gutkind, Nat. Rev. Mol. Cell Biol. 2004, 5, 998-1012.
- (2004) Nat. Rev. Mol. Cell Biol. , vol.5 , pp. 998-1012
- Sodhi, A.¹ Montaner, S.² Gutkind, J.E.³

41
- 0028981057
- S. Offermanns, M. I. Simon, J. Biol. Chem. 1995, 270, 15175-15180.
- (1995) J. Biol. Chem. , vol.270 , pp. 15175-15180
- Offermanns, S.¹ Simon, M.I.²

42
- 0027245830
- B. R. Conklin, Z. Farfel, K. D. Lustig, D. Julius, H. R. Bourne, Nature 1993, 363, 274-276.
- (1993) Nature , vol.363 , pp. 274-276
- Conklin, B.R.¹ Farfel, Z.² Lustig, K.D.³ Julius, D.⁴ Bourne, H.R.⁵

43
- 0036688175
- D. T. Chalmers, D. P. Behan, Nat. Drug Discov. Rev. 2002, 1, 599-607.
- (2002) Nat. Drug Discov. Rev. , vol.1 , pp. 599-607
- Chalmers, D.T.¹ Behan, D.P.²

44
- 0032574982
- L. M. McLatchie, N. J. Fraser, M. J. Main, A. Wise, J. Brown, N. Thompson, R. Solari, M. G. Lee, S. M. Foord, Nature 1998, 393, 333-339.
- (1998) Nature , vol.393 , pp. 333-339
- McLatchie, L.M.¹ Fraser, N.J.² Main, M.J.³ Wise, A.⁴ Brown, J.⁵ Thompson, N.⁶ Solari, R.⁷ Lee, M.G.⁸ Foord, S.M.⁹

45
- 0038380750
- G. Milligan, Drug Discovery Today 2003, 8, 579-585.
- (2003) Drug Discovery Today , vol.8 , pp. 579-585
- Milligan, G.¹

46
- 18844403391
- C. Grånäs, B. K. Lundholt, A. Heydorn, V. Linde, H.-C. Pedersen, C. Krog-Jensen, M. M. Rosenkilde, L. Pagliaro, Comb. Chem. High Throughput Screening 2005, 8, 301-309.
- (2005) Comb. Chem. High Throughput Screening , vol.8 , pp. 301-309
- Grånäs, C.¹ Lundholt, B.K.² Heydorn, A.³ Linde, V.⁴ Pedersen, H.-C.⁵ Krog-Jensen, C.⁶ Rosenkilde, M.M.⁷ Pagliaro, L.⁸

47
- 0042322842
- M. G. Ludwig, M. Vanek, D. Guerin, J. A. Gasser, C. E. Jones, U. Junker, H. Hofstetter, R. M. Wolf, K. Seuwen, Nature 2003, 425, 93-98.
- (2003) Nature , vol.425 , pp. 93-98
- Ludwig, M.G.¹ Vanek, M.² Guerin, D.³ Gasser, J.A.⁴ Jones, C.E.⁵ Junker, U.⁶ Hofstetter, H.⁷ Wolf, R.M.⁸ Seuwen, K.⁹

48
- 0034604451
- K. Palczewski, T. Kumasaka, T. Hori, C. A. Behnke, H. Motoshima, Science 2000, 289, 739-745.
- (2000) Science , vol.289 , pp. 739-745
- Palczewski, K.¹ Kumasaka, T.² Hori, T.³ Behnke, C.A.⁴ Motoshima, H.⁵

49
- 0030864048
- E. Pebay-Peyroula, G. Rummel, J. P. Rosenbusch, E. M. Landau, Science 1997, 277, 1676-1681.
- (1997) Science , vol.277 , pp. 1676-1681
- Pebay-Peyroula, E.¹ Rummel, G.² Rosenbusch, J.P.³ Landau, E.M.⁴

50
- 0027390821
- M. F. Hibert, S. Trumpp-Kallmeyer, J. Hofflack, Trends Pharmacol. Sci. 1993, 14, 7-12.
- (1993) Trends Pharmacol. Sci. , vol.14 , pp. 7-12
- Hibert, M.F.¹ Trumpp-Kallmeyer, S.² Hofflack, J.³

51
- 0343339895
- E. Jacoby, J. L. Fauchère, E. Raimbaud, S. Ollivier, A. Michel, M. Spedding, Quant. Struct.-Act. Relat. 1999, 18, 561-572.
- (1999) Quant. Struct.-Act. Relat. , vol.18 , pp. 561-572
- Jacoby, E.¹ Fauchère, J.L.² Raimbaud, E.³ Ollivier, S.⁴ Michel, A.⁵ Spedding, M.⁶

52
- 0037494099
- S. Filipek, D. C. Teller, K. Palczewski, R. Stenkamp, Annu. Rev. Biophys. Biomol. Struct. 2003, 32, 375-397.
- (2003) Annu. Rev. Biophys. Biomol. Struct. , vol.32 , pp. 375-397
- Filipek, S.¹ Teller, D.C.² Palczewski, K.³ Stenkamp, R.⁴

53
- 0034878886
- E. Jacoby, Quant. Struct.-Act. Relat. 2001, 20, 115-123.
- (2001) Quant. Struct.-Act. Relat. , vol.20 , pp. 115-123
- Jacoby, E.¹

54
- 0032735188
- D. R. Flower, Biochim. Biophys. Acta 1999, 1422, 207-234.
- (1999) Biochim. Biophys. Acta , vol.1422 , pp. 207-234
- Flower, D.R.¹

55
- 15144345036
- S. M. Bromidge, S. Dabbs, D. T. Davies, D. M. Duckworth, I. T. Forbes, P. Ham, G. E. Jones, F. D. King, D. V. Saunders, S. Starr, K. M. Thewlis, P. A. Wyman, F. E. Blaney, C. B. Naylor, F. Bailey, T. P. Blackburn, V. Holland, G. A. Kennett, G. J. Riley, M. D. Wood, J. Med Chem. 1998, 41, 1598-1612.
- (1998) J. Med Chem. , vol.41 , pp. 1598-1612
- Bromidge, S.M.¹ Dabbs, S.² Davies, D.T.³ Duckworth, D.M.⁴ Forbes, I.T.⁵ Ham, P.⁶ Jones, G.E.⁷ King, F.D.⁸ Saunders, D.V.⁹ Starr, S.¹⁰ Thewlis, K.M.¹¹ Wyman, P.A.¹² Blaney, F.E.¹³ Naylor, C.B.¹⁴ Bailey, F.¹⁵ Blackburn, T.P.¹⁶ Holland, V.¹⁷ Kennett, G.A.¹⁸ Riley, G.J.¹⁹ Wood, M.D.²⁰ more..

56
- 0842304428
- K. Bondensgaard, M. Ankersen, H. Thørgersen, B. S. Hansen, B. S. Wulff, R. P. Bywater, J. Med. Chem. 2004, 47, 888-899.
- (2004) J. Med. Chem. , vol.47 , pp. 888-899
- Bondensgaard, K.¹ Ankersen, M.² Thørgersen, H.³ Hansen, B.S.⁴ Wulff, B.S.⁵ Bywater, R.P.⁶

57
- 0038458865
- O. M. Becker, S. Shacham, Y. Marantz, S. Noiman, Curr. Opin. Drug Discovery Dev. 2003, 6, 353-361.
- (2003) Curr. Opin. Drug Discovery Dev. , vol.6 , pp. 353-361
- Becker, O.M.¹ Shacham, S.² Marantz, Y.³ Noiman, S.⁴

58
- 2942722780
- C. Bissantz, A. Logean, D. Rognan, J. Chem. Inf. Comput. Sci. 2004, 44, 1162-1176.
- (2004) J. Chem. Inf. Comput. Sci. , vol.44 , pp. 1162-1176
- Bissantz, C.¹ Logean, A.² Rognan, D.³

59
- 18744402177
- J. M. Klco, C. B. Wiegand, K. Narzinski, T. J. Baranski, Nat. Struct. Mol. Biol. 2005, 12, 320-326.
- (2005) Nat. Struct. Mol. Biol. , vol.12 , pp. 320-326
- Klco, J.M.¹ Wiegand, C.B.² Narzinski, K.³ Baranski, T.J.⁴

60
- 0036169280
- L. Shi, J. A. Javitch, Annu. Rev. Pharmacol. Toxicol. 2002, 42, 437-467.
- (2002) Annu. Rev. Pharmacol. Toxicol. , vol.42 , pp. 437-467
- Shi, L.¹ Javitch, J.A.²

61
- 6044260116
- A. Evers, G. Klebe, J. Med. Chem. 2004, 47, 5381-5392.
- (2004) J. Med. Chem. , vol.47 , pp. 5381-5392
- Evers, A.¹ Klebe, G.²

62
- 0037235663
- C. Bissantz, P. Bernard, M. Hibert, D. Rognan, Proteins Struct. Funct. Genet. 2003, 50, 5-25.
- (2003) Proteins Struct. Funct. Genet. , vol.50 , pp. 5-25
- Bissantz, C.¹ Bernard, P.² Hibert, M.³ Rognan, D.⁴

63
- 3843095917
- O. M. Becker, Y. Marantz, S. Shacham, B. Inbal, A. Heifetz, O. Kalid, S. Bar-Haim, D. Warhaviak, M. Fichman, S. Noiman, Proc. Natl. Acad. Sci. USA 2004, 101, 11 304-11 309.
- (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 11304-11309
- Becker, O.M.¹ Marantz, Y.² Shacham, S.³ Inbal, B.⁴ Heifetz, A.⁵ Kalid, O.⁶ Bar-Haim, S.⁷ Warhaviak, D.⁸ Fichman, M.⁹ Noiman, S.¹⁰

64
- 0032562699
- J. Ballesteros, S. Kitanovic, F. Guarnieri, P. Davies, B. J. Fromme, K. Konvicka, L. Chi, R. P. Millar, J. S. Davidson, H. Weinstein, S. C. Sealfon, J. Biol. Chem. 1998, 273, 10445-10453.
- (1998) J. Biol. Chem. , vol.273 , pp. 10445-10453
- Ballesteros, J.¹ Kitanovic, S.² Guarnieri, F.³ Davies, P.⁴ Fromme, B.J.⁵ Konvicka, K.⁶ Chi, L.⁷ Millar, R.P.⁸ Davidson, J.S.⁹ Weinstein, H.¹⁰ Sealfon, S.C.¹¹

65
- 0030840923
- T. Kenakin, Ann. N. Y. Acad. Sci. 1997, 812, 116-125.
- (1997) Ann. N. Y. Acad. Sci. , vol.812 , pp. 116-125
- Kenakin, T.¹

66
- 4444351153
- C. R. Grace, M. H. Perrin, M. R. DiGruccio, C. L. Miller, J. E. Rivier, W. W. Vale, R. Riek, Natl. Acad. Sci. USA 2004, 101, 12836-12841.
- (2004) Natl. Acad. Sci. USA , vol.101 , pp. 12836-12841
- Grace, C.R.¹ Perrin, M.H.² DiGruccio, M.R.³ Miller, C.L.⁴ Rivier, J.E.⁵ Vale, W.W.⁶ Riek, R.⁷

67
- 0347480255
- R. C. Gensure, N. Shimizu, J. Tsang, T. J. Gardella, Mol. Endocrinol. 2003, 17, 2647-2658.
- (2003) Mol. Endocrinol. , vol.17 , pp. 2647-2658
- Gensure, R.C.¹ Shimizu, N.² Tsang, J.³ Gardella, T.J.⁴

68
- 1342346546
- S. U. Miedlich, L. Gama, K. Seuwen, R. M. Wolf, G. E. Breitwieser, J. Biol. Chem. 2004, 279, 7254-7263.
- (2004) J. Biol. Chem. , vol.279 , pp. 7254-7263
- Miedlich, S.U.¹ Gama, L.² Seuwen, K.³ Wolf, R.M.⁴ Breitwieser, G.E.⁵

69
- 0034721795
- A. Pagano, D. Ruegg, S. Litschig, N. Stoehr, C. Stierlin, M. Heinrich, P. Floersheim, L. Prezeau, F. Carroll, J. P. Pin, A. Cambria, I. Vranesic, P. J. Flor, F. Gasparini, R. Kuhn, J. Biol. Chem. 2000, 275, 33750-33758.
- (2000) J. Biol. Chem. , vol.275 , pp. 33750-33758
- Pagano, A.¹ Ruegg, D.² Litschig, S.³ Stoehr, N.⁴ Stierlin, C.⁵ Heinrich, M.⁶ Floersheim, P.⁷ Prezeau, L.⁸ Carroll, F.⁹ Pin, J.P.¹⁰ Cambria, A.¹¹ Vranesic, I.¹² Flor, P.J.¹³ Gasparini, F.¹⁴ Kuhn, R.¹⁵

70
- 0036174608
- S. Angers, A. Salahpour, M. Bouvier, Annu. Rev. Pharmacol. Toxicol. 2002, 42, 409-435.
- (2002) Annu. Rev. Pharmacol. Toxicol. , vol.42 , pp. 409-435
- Angers, S.¹ Salahpour, A.² Bouvier, M.³

71
- 3042663287
- G. Milligan, Mol. Pharmacol. 2004, 66, 1-7.
- (2004) Mol. Pharmacol. , vol.66 , pp. 1-7
- Milligan, G.¹

72
- 3242773021
- S. Filipek, K. A. Krzysko, D. Fotiadis, Y. Liang, D. A. Saperstein, A. Engel, K. Palczewski, Photochem. Photobiol. Sci. 2004, 3, 628-638.
- (2004) Photochem. Photobiol. Sci. , vol.3 , pp. 628-638
- Filipek, S.¹ Krzysko, K.A.² Fotiadis, D.³ Liang, Y.⁴ Saperstein, D.A.⁵ Engel, A.⁶ Palczewski, K.⁷

73
- 0038392702
- J. L. Baneres, J. Parello, J. Mol. Biol. 2003, 329, 815-829.
- (2003) J. Mol. Biol. , vol.329 , pp. 815-829
- Baneres, J.L.¹ Parello, J.²

74
- 12344250438
- K. Lundstrom, Trends Biotechnol. 2005, 23, 103-108.
- (2005) Trends Biotechnol. , vol.23 , pp. 103-108
- Lundstrom, K.¹

75
- 2942667923
- K. H. Bleicher, L. G. Green, R. E. Martin, M. Rogers-Evans, Curr. Opin. Chem. Biol. 2004, 8, 287-296.
- (2004) Curr. Opin. Chem. Biol. , vol.8 , pp. 287-296
- Bleicher, K.H.¹ Green, L.G.² Martin, R.E.³ Rogers-Evans, M.⁴

76
- 4043107079
- P. Jimonet, R. Jäger, Curr. Opin. Drug Discovery Dev. 2004, 7, 325-333.
- (2004) Curr. Opin. Drug Discovery Dev. , vol.7 , pp. 325-333
- Jimonet, P.¹ Jäger, R.²

77
- 2942668771
- R. Crossley, Curr. Top. Med. Chem. 2004, 4, 581-588.
- (2004) Curr. Top. Med. Chem. , vol.4 , pp. 581-588
- Crossley, R.¹

78
- 0036835460
- J. Bajorath, Nat. Rev. Drug Discovery 2002, 1, 882-894.
- (2002) Nat. Rev. Drug Discovery , vol.1 , pp. 882-894
- Bajorath, J.¹

79
- 2942564021
- M. M. Hann, T. I. Oprea, Curr. Opin. Chem. Biol. 2004, 8, 255-263.
- (2004) Curr. Opin. Chem. Biol. , vol.8 , pp. 255-263
- Hann, M.M.¹ Oprea, T.I.²

80
- 0032961958
- S. Halazy, Expert Opin. Ther. Pat. 1999, 9, 431-446.
- (1999) Expert Opin. Ther. Pat. , vol.9 , pp. 431-446
- Halazy, S.¹

81
- 15444364860
- D. J. Daniels, A. Kulkarni, Z. Xie, R. G. Bhushan, P. S. Portoghese, J. Med. Chem. 2005, 48, 1713-1716.
- (2005) J. Med. Chem. , vol.48 , pp. 1713-1716
- Daniels, D.J.¹ Kulkarni, A.² Xie, Z.³ Bhushan, R.G.⁴ Portoghese, P.S.⁵

82
- 0036834372
- V. J. Hruby, Nat. Rev. Drug Discovery. 2002, 1, 847-858.
- (2002) Nat. Rev. Drug Discovery , vol.1 , pp. 847-858
- Hruby, V.J.¹

83
- 0348142123
- M. Eguchi, M. McMillan, C. Nguyen, J. L. Teo, E. Y. Chi, W. R. Henderson, Jr., M. Kahn, Comb. Chem. High Throughput Screening 2003, 6, 611-621.
- (2003) Comb. Chem. High Throughput Screening , vol.6 , pp. 611-621
- Eguchi, M.¹ McMillan, M.² Nguyen, C.³ Teo, J.L.⁴ Chi, E.Y.⁵ Henderson Jr., W.R.⁶ Kahn, M.⁷

84
- 17844371263
- (Eds.: H. Kubinyi, G. Müller), Wiley-VCH, Weinheim
- T. R. Webb in Chemogenomics in Drug Discovery-A Medicinal Chemistry Perspective (Eds.: H. Kubinyi, G. Müller), Wiley-VCH, Weinheim, 2004, pp. 313-324.
- (2004) Chemogenomics in Drug Discovery - A Medicinal Chemistry Perspective , pp. 313-324
- Webb, T.R.¹

85
- 0032818586
- S. L. Garland, P. M. Dean, J. Comput.-Aided Mol. Des. 1999, 13, 469-483.
- (1999) J. Comput.-Aided Mol. Des. , vol.13 , pp. 469-483
- Garland, S.L.¹ Dean, P.M.²

86
- 0032842085
- S. L. Garland, P. M. Dean, J. Comput.-Aided Mol. Des. 1999, 13, 485-498.
- (1999) J. Comput.-Aided Mol. Des. , vol.13 , pp. 485-498
- Garland, S.L.¹ Dean, P.M.²

87
- 0024239320
- B. E. Evans, K. E. Rittle, M. G. Bock, R. M. DiPardo, R. M. Freidinger, W. L. Whitter, G. F. Lundell, D. F. Veber, P. S. Anderson, R. S. Chang, J. Med. Chem. 1988, 31, 2235-2246.
- (1988) J. Med. Chem. , vol.31 , pp. 2235-2246
- Evans, B.E.¹ Rittle, K.E.² Bock, M.G.³ DiPardo, R.M.⁴ Freidinger, R.M.⁵ Whitter, W.L.⁶ Lundell, G.F.⁷ Veber, D.F.⁸ Anderson, P.S.⁹ Chang, R.S.¹⁰

88
- 35448950092
- (Ed: G. L. Trainor), Academic Press, San Diego
- A. A. Patchett, R. P. Nargund in Annual Reports in Medicinal Chemistry Vol. 35 (Ed: G. L. Trainor), Academic Press, San Diego, 2000, pp. 289-298.
- (2000) Annual Reports in Medicinal Chemistry Vol. 35 , vol.35 , pp. 289-298
- Patchett, A.A.¹ Nargund, R.P.²

89
- 17844408611
- (Eds.: H. Kubinyi, G. Müller), Wiley-VCH, Weinheim
- G. Müller in Chemogenomics in Drug Discovery-A Medicinal Chemistry Perspective (Eds.: H. Kubinyi, G. Müller), Wiley-VCH, Weinheim, 2004, pp. 7-42.
- (2004) Chemogenomics in Drug Discovery - A Medicinal Chemistry Perspective , pp. 7-42
- Müller, G.¹

90
- 4243133144
- T. Guo, D. W. Hobbs, Assay Drug Dev. Technol. 2003, 7, 579-592.
- (2003) Assay Drug Dev. Technol. , vol.7 , pp. 579-592
- Guo, T.¹ Hobbs, D.W.²

91
- 18244382828
- C. A. Willoughby, S. M. Hutchins, K. G. Rosauer, M. J. Dhar, K. T. Chapman, G. G. Chicchi, S. Sadowski, D. H. Weinberg, S. Patel, L. Malkowitz, J. Di Salvo, S. G. Pacholok, K. Cheng, Bioorg. Med. Chem. Lett. 2002, 12, 93-96.
- (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 93-96
- Willoughby, C.A.¹ Hutchins, S.M.² Rosauer, K.G.³ Dhar, M.J.⁴ Chapman, K.T.⁵ Chicchi, G.G.⁶ Sadowski, S.⁷ Weinberg, D.H.⁸ Patel, S.⁹ Malkowitz, L.¹⁰ Di Salvo, J.¹¹ Pacholok, S.G.¹² Cheng, K.¹³

92
- 0037835538
- R. P. Sheridan, J. Chem. Inf. Comput. Sci. 2003, 43, 1037-1050.
- (2003) J. Chem. Inf. Comput. Sci. , vol.43 , pp. 1037-1050
- Sheridan, R.P.¹

93
- 0029894013
- G. W. Bemis, M. A. Murcko, J. Med. Chem. 1996, 39, 2887-2893.
- (1996) J. Med. Chem. , vol.39 , pp. 2887-2893
- Bemis, G.W.¹ Murcko, M.A.²

94
- 1542268206
- C. G. Wermuth, J. Med. Chem. 2004, 47, 1303-1314.
- (2004) J. Med. Chem. , vol.47 , pp. 1303-1314
- Wermuth, C.G.¹

95
- 0036740917
- R. P. Sheridan, S. K. Kearsley, Drug Discovery Today 2002, 4, 903-911.
- (2002) Drug Discovery Today , vol.4 , pp. 903-911
- Sheridan, R.P.¹ Kearsley, S.K.²

96
- 10244222365
- J. Hert, P. Willett, D. J. Wilton, P. Acklin, K. Azzaoui, E. Jacoby, A. Schuffenhauer, Org. Biomol. Chem. 2004, 2, 3256-3266.
- (2004) Org. Biomol. Chem. , vol.2 , pp. 3256-3266
- Hert, J.¹ Willett, P.² Wilton, D.J.³ Acklin, P.⁴ Azzaoui, K.⁵ Jacoby, E.⁶ Schuffenhauer, A.⁷

97
- 0038170311
- A. Schuffenhauer, P. Floersheim, P. Acklin, E. Jacoby, J. Chem. Inf. Comput. Sci. 2003, 43, 391-405.
- (2003) J. Chem. Inf. Comput. Sci. , vol.43 , pp. 391-405
- Schuffenhauer, A.¹ Floersheim, P.² Acklin, P.³ Jacoby, E.⁴

98
- 3342907009
- N. P. Savchuck, K. V. Balakin, S. E. Tkachenko, Curr. Opin. Chem. Biol. 2004, 8, 412-417.
- (2004) Curr. Opin. Chem. Biol. , vol.8 , pp. 412-417
- Savchuck, N.P.¹ Balakin, K.V.² Tkachenko, S.E.³

99
- 2942715359
- M. von Korff, M. Steger, J. Chem. Inf. Comput. Sci. 2004, 44, 1137-1147.
- (2004) J. Chem. Inf. Comput. Sci. , vol.44 , pp. 1137-1147
- Von Korff, M.¹ Steger, M.²

100
- 0034130399
- G. Schneider, M. L. Lee, M. Stahl, P. Schneider, J. Comput.-Aided Mol. Des. 2000, 14, 487-494.
- (2000) J. Comput.-Aided Mol. Des. , vol.14 , pp. 487-494
- Schneider, G.¹ Lee, M.L.² Stahl, M.³ Schneider, P.⁴

101
- 1842477318
- G. Jenkins, Curr. Drug Discovery Technol. 2004, 3, 23-26.
- (2004) Curr. Drug Discovery Technol. , vol.3 , pp. 23-26
- Jenkins, G.¹

102
- 0036628560
- A. Schuffenhauer, J. Zimmermann, R. Stoop, J. J. van der Vyver, S. Lecchini, E. Jacoby, J. Chem. Inf. Comput. Sci. 2002, 42, 947-955.
- (2002) J. Chem. Inf. Comput. Sci. , vol.42 , pp. 947-955
- Schuffenhauer, A.¹ Zimmermann, J.² Stoop, R.³ Van Der Vyver, J.J.⁴ Lecchini, S.⁵ Jacoby, E.⁶

103
- 0043031339
- C. M. Krejsa, D. Horvath, S. L. Rogalski, J. E. Penzotti, B. Mao, F. Barbosa, J. C. Migeon, Curr. Opin. Drug Discovery Dev. 2003, 6, 470-480.
- (2003) Curr. Opin. Drug Discovery Dev. , vol.6 , pp. 470-480
- Krejsa, C.M.¹ Horvath, D.² Rogalski, S.L.³ Penzotti, J.E.⁴ Mao, B.⁵ Barbosa, F.⁶ Migeon, J.C.⁷

104
- 17844391829
- H. Roter, Curr. Opin. Drug Discovery Dev. 2005, 8, 309-315.
- (2005) Curr. Opin. Drug Discovery Dev. , vol.8 , pp. 309-315
- Roter, H.¹

105
- 21044451732
- T. Klabunde, A. Evers, ChemBioChem 2005, 6, 876-889.
- (2005) ChemBioChem , vol.6 , pp. 876-889
- Klabunde, T.¹ Evers, A.²

106
- 12844261677
- E. S. Huang, Drug Discovery Today 2005, 10, 69-73.
- (2005) Drug Discovery Today , vol.10 , pp. 69-73
- Huang, E.S.¹

107
- 0037385599
- A. Gaulton, T. K. Attwood, Curr. Opin. Pharmacol. 2003, 3, 114-120.
- (2003) Curr. Opin. Pharmacol. , vol.3 , pp. 114-120
- Gaulton, A.¹ Attwood, T.K.²

108
- 0038309559
- E. S. Huang, Protein Sci. 2003, 12, 1360-1367.
- (2003) Protein Sci. , vol.12 , pp. 1360-1367
- Huang, E.S.¹

109
- 22944479010
- T. M. Frimurer, T. Ulven, C. E. Elling, L. O. Gerlach, E. Kostenis, T. Hogberg, Bioorg. Med. Chem. Lett. 2005, 15, 3707-3712.
- (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 3707-3712
- Frimurer, T.M.¹ Ulven, T.² Elling, C.E.³ Gerlach, L.O.⁴ Kostenis, E.⁵ Hogberg, T.⁶

110
- 0037674938
- C. Y. Lin, M. G. Varma, A. Joubel, S. Madabushi, O. Lichtarge, D. L. Barber, J. Biol. Chem. 2003, 278, 15 128-15 135.
- (2003) J. Biol. Chem. , vol.278
- Lin, C.Y.¹ Varma, M.G.² Joubel, A.³ Madabushi, S.⁴ Lichtarge, O.⁵ Barber, D.L.⁶

111
- 0041932071
- A. Cacace, M. Banks, T. Spicer, F. Civoli, J. Watson, Drug Discovery Today 2003, 8, 785-792.
- (2003) Drug Discovery Today , vol.8 , pp. 785-792
- Cacace, A.¹ Banks, M.² Spicer, T.³ Civoli, F.⁴ Watson, J.⁵

112
- 2442495434
- D. Gabriel, M. Vernier, M. J. Pfeifer, B. Dasen, L. Tenaillon, R. Bouhelal, Assay Drug Dev. Technol. 2003, 1, 291-303.
- (2003) Assay Drug Dev. Technol. , vol.1 , pp. 291-303
- Gabriel, D.¹ Vernier, M.² Pfeifer, M.J.³ Dasen, B.⁴ Tenaillon, L.⁵ Bouhelal, R.⁶

113
- 18844454054
- R. M. Eglen, Comb. Chem. High Throughput Screening 2005, 8, 311-318.
- (2005) Comb. Chem. High Throughput Screening , vol.8 , pp. 311-318
- Eglen, R.M.¹

114
- 18844370417
- C. Williams, A. Sewing, Comb. Chem. High Throughput Screening 2005, 8, 285-292.
- (2005) Comb. Chem. High Throughput Screening , vol.8 , pp. 285-292
- Williams, C.¹ Sewing, A.²

115
- 0032199006
- D. Colquhoun, Br. J. Pharmacol. 1998, 125, 924-947.
- (1998) Br. J. Pharmacol. , vol.125 , pp. 924-947
- Colquhoun, D.¹

116
- 0034714211
- I. Sabroe, M. J. Peck, B. J. van Keulen, A. Jorritsma, G. Simmons, P. R. Clapham, T. J. Williams, J. E. Pease, J. Biol. Chem. 2000, 275, 25 985-25 992.
- (2000) J. Biol. Chem. , vol.275
- Sabroe, I.¹ Peck, M.J.² Van Keulen, B.J.³ Jorritsma, A.⁴ Simmons, G.⁵ Clapham, P.R.⁶ Williams, T.J.⁷ Pease, J.E.⁸

117
- 0034031410
- M. Marcoli, S. Scarrone, G. Maura, G. Bonanno, M. Raiteri, J. Pharmacol. Exp. Ther. 2000, 293, 42-47.
- (2000) J. Pharmacol. Exp. Ther. , vol.293 , pp. 42-47
- Marcoli, M.¹ Scarrone, S.² Maura, G.³ Bonanno, G.⁴ Raiteri, M.⁵

118
- 0347480490
- D. Gurwitz, R. Haring, Drug Discovery Today 2003, 8, 1108-1109.
- (2003) Drug Discovery Today , vol.8 , pp. 1108-1109
- Gurwitz, D.¹ Haring, R.²

119
- 17844400325
- H. P. Fischer, S. Heyse, Curr. Opin. Drug Discovery Dev. 2005, 8, 334-346.
- (2005) Curr. Opin. Drug Discovery Dev. , vol.8 , pp. 334-346
- Fischer, H.P.¹ Heyse, S.²

120
- 0037794320
- T. Kenakin, Nat. Rev. Drug Discovery 2003, 2, 429-438.
- (2003) Nat. Rev. Drug Discovery , vol.2 , pp. 429-438
- Kenakin, T.¹

121
- 4644221872
- A. Couve, A. R. Calver, B. Fairfax, S. J. Moss, M. N. Pangalos, Biochem. Pharmacol. 2004, 68, 1527-1536.
- (2004) Biochem. Pharmacol. , vol.68 , pp. 1527-1536
- Couve, A.¹ Calver, A.R.² Fairfax, B.³ Moss, S.J.⁴ Pangalos, M.N.⁵

122
- 21144446486
- M. Waldhoer, J. Fong, R. M. Jones, M. M. Lunzer, S. K. Sharma, E. Kostenis, P. S. Portoghese, J. L. Whistler, Proc. Natl. Acad. Sci. USA 2005, 102, 9050-9055.
- (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 9050-9055
- Waldhoer, M.¹ Fong, J.² Jones, R.M.³ Lunzer, M.M.⁴ Sharma, S.K.⁵ Kostenis, E.⁶ Portoghese, P.S.⁷ Whistler, J.L.⁸

123
- 4644260473
- J. Bockaert, L. Fagni, A. Dumuis, P. Marin, Pharmacol. Ther. 2004, 103, 203-221.
- (2004) Pharmacol. Ther. , vol.103 , pp. 203-221
- Bockaert, J.¹ Fagni, L.² Dumuis, A.³ Marin, P.⁴

124
- 0037421590
- W. E. Evans, H. L. McLeod, N. Engl. J. Med. 2003, 348, 538-549.
- (2003) N. Engl. J. Med. , vol.348 , pp. 538-549
- Evans, W.E.¹ McLeod, H.L.²

125
- 0041506933
- K. M. Small, D. W. McGraw, S. B. Liggett, Annu. Rev. Pharmacol. Toxicol. 2003, 43, 381-411.
- (2003) Annu. Rev. Pharmacol. Toxicol. , vol.43 , pp. 381-411
- Small, K.M.¹ McGraw, D.W.² Liggett, S.B.³

126
- 1342333596
- E. A. Hallem, A. Nicole Fox, L. J. Zwiebel, J. R. Carlson, Nature 2004, 427, 212-213.
- (2004) Nature , vol.427 , pp. 212-213
- Hallem, E.A.¹ Nicole Fox, A.² Zwiebel, L.J.³ Carlson, J.R.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.