High-throughput modeling of human g-protein coupled receptors: Amino acid sequence alignment, three-dimensional model building, and receptor library screening

Journal of Chemical Information and Computer Sciences

Volumn 44, Issue 3, 2004, Pages 1162-1176

  Bissantz, Caterina ^a,b   Logean, Antoine ^a   Rognan, Didier ^a  

^a Laboratoire de Pharmacochimie   (France)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; COMPUTATIONAL METHODS; DATABASE SYSTEMS; DRUG PRODUCTS; MARKETING; MATHEMATICAL MODELS; MOLECULAR WEIGHT; PATTERN RECOGNITION;

HUMAN G-PROTEIN COUPLED RECEPTORS; LIGAND BINDING CAVITY; METABOTROPIC-LIKE RECEPTORS; RECEPTOR LIBRARY;

PROTEINS;

G PROTEIN COUPLED RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL MODEL; CHEMISTRY; DRUG ANTAGONISM; DRUG POTENTIATION; HUMAN; MOLECULAR GENETICS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; HUMANS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 2942722780     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci034181a     Document Type: Article

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