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Volumn 275, Issue 34, 2000, Pages 25985-25992

A small molecule antagonist of chemokine receptors CCR1 and CCR3: Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry

(8) Sabroe, Ian a Peck, Michael J b Van Keulen, Berend Jan b Jorritsma, Annelies a Simmons, Graham c Clapham, Paul R c Williams, Timothy J a Pease, James E a

a IMPERIAL COLLEGE SCHOOL OF MEDICINE (United Kingdom)

b UCB PHARMA (Belgium)

c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR3; EOTAXIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 4; RECEPTOR BLOCKING AGENT; UCB 35625; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTHMA; CHEMOTAXIS; DRUG POTENCY; DRUG SELECTIVITY; EOSINOPHIL; GENE EXPRESSION; GENE FUNCTION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034714211 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M908864199 Document Type: Article

Times cited : (215)

References (58)

1
- 0026672543
- (1992) Immunol. Today , vol.13 , pp. 384-387
- Spry, C.J.¹ Kay, A.B.² Gleich, G.J.³

2
- 0025037094
- (1990) N. Engl. J. Med. , vol.323 , pp. 1033-1039
- Bousquet, J.¹ Chanez, P.² Lacoste, J.Y.³ Barneon, G.⁴ Ghavanian, M.N.⁵ Enander, I.⁶ Venge, P.⁷ Ahlstedt, S.⁸ Simony-Lafontaine, J.⁹ Godard, P.¹⁰ Michel, P.-B.¹¹

3
- 0023785820
- (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 685-688
- Flavahan, N.A.¹ Slifman, N.R.² Gleich, G.J.³ Vanhoutte, P.M.⁴

4
- 0024271351
- (1988) Am. Rev. Respir. Dis. , vol.138 , Issue.SUPPL. , pp. 54-57
- Venge, P.¹ Dahl, R.² Fredens, K.³ Peterson, C.G.⁴

5
- 0032509889
- (1998) N. Engl. J. Med. , vol.338 , pp. 436-445
- Luster, A.D.¹

6
- 0028140133
- (1994) J. Exp. Med. , vol.179 , pp. 881-887
- Jose, P.J.¹ Griffiths-Johnson, D.A.² Collins, P.D.³ Walsh, D.T.⁴ Moqbel, R.⁵ Totty, N.F.⁶ Truong, O.⁷ Hsuan, J.J.⁸ Williams, T.J.⁹

7
- 0027992662
- (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 788-794
- Jose, P.J.¹ Adcock, I.M.² Griffiths-Johnson, D.A.³ Berkman, N.⁴ Wells, T.N.C.⁵ Williams, T.J.⁶ Power, C.A.⁷

8
- 13344283419
- (1996) J. Clin. Invest. , vol.97 , pp. 604-612
- Ponath, P.D.¹ Qin, S.² Ringler, D.J.³ Clark-Lewis, I.⁴ Wang, J.⁵ Kassam, N.⁶ Smith, H.⁷ Shi, X.⁸ Gonzalo, J.-A.⁹ Newman, W.¹⁰ Gutierrez-Ramos, J.-C.¹¹ Mackay, C.R.¹²

9
- 0029056907
- (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 8960-8964
- Rothenberg, M.E.¹ Luster, A.D.² Leder, P.³

10
- 0031974631
- (1998) Immunogenetics , vol.47 , pp. 178-180
- Williams, C.M.M.¹ Newton, D.J.² Wilson, S.A.³ Williams, T.J.⁴ Coleman, J.W.⁵ Flanagan, B.F.⁶

11
- 0031445441
- (1997) Eur. J. Immunol. , vol.27 , pp. 3507-3516
- Ying, S.¹ Robinson, D.S.² Meng, Q.³ Rottman, J.⁴ Kennedy, R.⁵ Ringler, D.J.⁶ Mackay, C.R.⁷ Daugherty, B.L.⁸ Springer, M.S.⁹ Durham, S.R.¹⁰ Williams, T.J.¹¹ Kay, A.B.¹²

12
- 0030808056
- (1997) J. Exp. Med. , vol.186 , pp. 601-612
- Humbles, A.A.¹ Conroy, D.M.² Marleau, S.³ Rankin, S.M.⁴ Palframan, R.T.⁵ Proudfoot, A.E.⁶ Wells, T.N.⁷ Li, D.⁸ Jeffery, P.K.⁹ Griffiths-Johnson, D.A.¹⁰ Williams, T.J.¹¹ Jose, P.J.¹²

13
- 0030930736
- (1997) Eur. Respir. J. , vol.10 , pp. 1946-1954
- Li, D.¹ Wang, D.² Griffiths-Johnson, D.A.³ Wells, T.N.C.⁴ Williams, T.J.⁵ Jose, P.J.⁶ Jeffery, P.K.⁷

14
- 0029148025
- (1995) J. Exp. Med. , vol.182 , pp. 1169-1174
- Collins, P.D.¹ Marleau, S.² Griffiths-Johnson, D.A.³ Jose, P.J.⁴ Williams, T.J.⁵

15
- 0032476608
- (1998) J. Exp. Med. , vol.188 , pp. 1621-1632
- Palframan, R.T.¹ Collins, P.D.² Severs, N.J.³ Rothery, S.⁴ Williams, T.J.⁵ Rankin, S.M.⁶

16
- 0032055540
- (1998) Blood , vol.91 , pp. 2240-2248
- Palframan, R.T.¹ Collins, P.D.² Williams, T.J.³ Rankin, S.M.⁴

17
- 0029961451
- (1996) J. Exp. Med. , vol.184 , pp. 1461-1469
- MacLean, J.A.¹ Ownbey, R.² Luster, A.D.³

18
- 0032545213
- (1998) Science , vol.282 , pp. 2258-2261
- Wills-Karp, M.¹ Luyimbazi, J.² Xu, X.³ Schofield, B.⁴ Neben, T.Y.⁵ Karp, C.L.⁶ Donaldson, D.D.⁷

19
- 0033560126
- (1999) J. Clin. Invest. , vol.103 , pp. 779-788
- Zhu, Z.¹ Homer, R.J.² Wang, Z.³ Chen, Q.⁴ Geba, G.P.⁵ Wang, J.⁶ Zhang, Y.⁷ Elias, J.A.⁸

20
- 0033104696
- (1999) J. Immunol. , vol.162 , pp. 2477-2487
- Li, L.¹ Xia, Y.² Nguyen, A.³ Lai, Y.H.⁴ Feng, L.⁵ Mosmann, T.R.⁶ Lo, D.⁷

21
- 0029898807
- (1996) J. Exp. Med. , vol.183 , pp. 2437-2448
- Ponath, P.D.¹ Qin, S.² Post, T.W.³ Wang, J.⁴ Wu, L.⁵ Gerard, N.P.⁶ Newman, W.⁷ Gerard, C.⁸ Mackay, C.R.⁹

22
- 0029060674
- Correction (1995) J. Biol. Chem. 270, 30235
- (1995) J. Biol. Chem. , vol.270 , pp. 16491-16494
- Combadiere, C.¹ Ahuja, S.K.² Murphy, P.M.³

23
- 0028809554
- (1995) J. Immunol. , vol.155 , pp. 5299-5306
- Post, T.W.¹ Bozic, C.R.² Rothenberg, M.E.³ Luster, A.D.⁴ Gerard, N.⁵ Gerard, C.⁶

24
- 0030601109
- (1996) Biochem. Biophys. Res. Commun. , vol.223 , pp. 679-684
- Gao, J.-L.¹ Sen, A.I.² Kitaura, M.³ Yoshie, O.⁴ Rothenberg, M.E.⁵ Murphy, P.M.⁶ Luster, A.D.⁷

25
- 0032400964
- (1998) J. Immunol. , vol.161 , pp. 6139-6147
- Sabroe, I.¹ Conroy, D.M.² Gerard, N.P.³ Li, Y.⁴ Collins, P.D.⁵ Post, T.W.⁶ Jose, P.J.⁷ Williams, T.J.⁸ Gerard, C.⁹ Ponath, P.D.¹⁰

26
- 0030980816
- (1997) J. Exp. Med. , vol.185 , pp. 2171-2176
- Forssmann, U.¹ Uguccioni, M.² Loetscher, P.³ Dahinden, C.A.⁴ Langen, H.⁵ Thelen, M.⁶ Baggiolini, M.⁷

27
- 0033178760
- (1999) J. Immunol. , vol.163 , pp. 1602-1610
- Shinkai, A.¹ Yoshisue, H.² Koike, M.³ Shoji, E.⁴ Nakagawa, S.⁵ Saito, A.⁶ Takeda, T.⁷ Imabeppu, S.⁸ Kato, Y.⁹ Hanai, N.¹⁰ Anazawa, H.¹¹ Kuga, T.¹² Nishi, T.¹³

28
- 0031028365
- (1997) J. Clin. Invest. , vol.99 , pp. 178-184
- Heath, H.¹ Qin, S.² Wu, L.³ LaRosa, G.⁴ Kassam, N.⁵ Ponath, P.D.⁶ Mackay, C.R.⁷

29
- 0030884894
- (1997) J. Clin. Invest. , vol.100 , pp. 1137-1143
- Uguccioni, M.¹ Mackay, C.R.² Ochensberger, B.³ Loetscher, P.⁴ Rhis, S.⁵ LaRosa, G.J.⁶ Rao, P.⁷ Ponath, P.D.⁸ Baggiolini, M.⁹ Dahinden, C.A.¹⁰

30
- 0030769920
- (1997) Science , vol.277 , pp. 2005-2007
- Sallusto, F.¹ Mackay, C.R.² Lanzavecchia, A.³

31
- 0033105639
- (1999) J. Immunol. , vol.162 , pp. 2946-2955
- Sabroe, I.¹ Hartnell, A.² Jopling, L.A.³ Bel, S.⁴ Ponath, P.D.⁵ Pease, J.E.⁶ Collins, P.D.⁷ Williams, T.J.⁸

32
- 0029876876
- (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1398-1404
- Alam, R.¹ York, J.² Boyars, M.³ Stafford, S.⁴ Grant, J.A.⁵ Lee, J.⁶ Forsythe, P.⁷ Sim, T.⁸ Ida, N.⁹

33
- 0032493767
- (1998) J. Biol. Chem. , vol.273 , pp. 19972-19976
- Pease, J.E.¹ Wang, J.² Ponath, P.D.³ Murphy, P.M.⁴

34
- 0033542116
- (1999) Biochem. Biophys. Res. Commun. , vol.258 , pp. 313-321
- Soda, Y.¹ Shimizu, N.² Jinno, A.³ Liu, H.Y.⁴ Kanbe, K.⁵ Kitamura, T.⁶ Hoshino, H.⁷

35
- 0021908138
- (1985) Am. J. Pathol. , vol.119 , pp. 101-110
- Haslett, C.¹ Guthrie, L.A.² Kopaniak, M.M.³ Johnston, R.B.⁴ Henson, P.M.⁵

36
- 0009644628
- (1958) Br. J. Pharmacol. , vol.14 , pp. 48-58
- Arunlakshana, O.¹ Schild, H.O.²

37
- 0031066829
- (1997) J. Immunol. , vol.158 , pp. 1361-1369
- Sabroe, I.¹ Williams, T.J.² Hebert, C.A.³ Collins, P.D.⁴

38
- 0033644748
- Methods in Molecular Biology (Proudfoot, A. E. I., Wells, T. N. C., and Power, C. A., eds) 1st Ed., Vol. 138, Humana Press, Totowa, NJ
- (2000) , pp. 209-222
- Reeves, J.D.¹ Simmons, G.²

39
- 0030825407
- (1997) Blood , vol.90 , pp. 909-928
- Rollins, B.J.¹

40
- 0027462365
- (1993) Cell , vol.72 , pp. 415-425
- Neote, K.¹ DiGregorio, D.² Mak, J.Y.³ Horuk, R.⁴ Schall, T.J.⁵

41
- 0033525711
- (1999) J. Biol. Chem. , vol.274 , pp. 6027-6030
- Ali, H.¹ Richardson, R.M.² Haribabu, B.³ Snyderman, R.⁴

42
- 0005014748
- (1996) Cell , vol.85 , pp. 1135-1148
- Choe, H.¹ Farzan, M.² Sun, Y.³ Sullivan, N.⁴ Rollins, B.⁵ Ponath, P.D.⁶ Wu, L.⁷ Mackay, C.R.⁸ LaRosa, G.⁹ Newman, W.¹⁰ Gerard, N.¹¹ Gerard, C.¹² Sodroski, J.¹³

43
- 19244380883
- (1997) Nature , vol.385 , pp. 645-649
- He, J.¹ Chen, Y.² Farzan, M.³ Choe, H.⁴ Ohagen, A.⁵ Gartner, S.⁶ Busciglio, J.⁷ Yang, X.⁸ Hofmann, W.⁹ Newman, W.¹⁰ Mackay, C.R.¹¹ Sodroski, J.¹² Gabuzda, D.¹³

44
- 0030878996
- (1997) J. Biol. Chem. , vol.272 , pp. 20420-20426
- Alkhatib, G.¹ Berger, E.A.² Murphy, P.M.³ Pease, J.E.⁴

45
- 0026656502
- (1992) J. Virol. , vol.66 , pp. 3531-3537
- Clapham, P.R.¹ McKnight, A.² Weiss, R.A.³

46
- 0029684314
- (1996) Science , vol.272 , pp. 954-956
- Gura, T.¹

47
- 0026446365
- (1992) J. Exp. Med. , vol.176 , pp. 1489-1495
- Rot, A.¹ Krieger, M.² Brunner, T.³ Bischoff, S.C.⁴ Schall, T.J.⁵ Dahinden, C.A.⁶

48
- 0028897310
- (1995) Eur. J. Immunol. , vol.25 , pp. 64-68
- Uguccioni, M.¹ D'Apuzzo, M.² Loetscher, M.³ Dewald, B.⁴ Baggiolini, M.⁵

49
- 14444283367
- (1998) J. Biol. Chem. , vol.273 , pp. 15687-15692
- Hesselgesser, J.¹ Ng, H.P.² Liang, M.³ Zheng, W.⁴ May, K.⁵ Bauman, J.G.⁶ Monahan, S.⁷ Islam, I.⁸ Wei, G.P.⁹ Ghannam, A.¹⁰ Taub, D.D.¹¹ Rosser, M.¹² Snider, R.M.¹³ Morrissey, M.M.¹⁴ Perez, H.D.¹⁵ Horuk, R.¹⁶

50
- 0030666946
- (1997) J. Biol. Chem. , vol.272 , pp. 28206-28209
- Dairaghi, D.J.¹ Oldham, E.R.² Bacon, K.B.³ Schall, T.J.⁴

51
- 0033525590
- (1999) Cell , vol.96 , pp. 667-676
- Farzan, M.¹ Mirzabekov, T.² Kolchinsky, P.³ Wyatt, R.⁴ Cayabyab, M.⁵ Gerard, N.P.⁶ Gerard, C.⁷ Sodroski, J.⁸ Choe, H.⁹

52
- 0034677770
- (2000) J. Biol. Chem. , vol.275 , pp. 7787-7794
- Elsner, J.¹ Mack, M.² Bruhl, H.³ Dulkys, Y.⁴ Kimmig, D.⁵ Simmons, G.⁶ Clapham, P.R.⁷ Schlondorff, D.⁸ Kapp, A.⁹ Wells, T.N.¹⁰ Proudfoot, A.E.¹¹

53
- 0032902710
- (1999) J. Virol. , vol.73 , pp. 4145-4155
- Olson, W.C.¹ Rabut, G.E.² Nagashima, K.A.³ Tran, D.N.⁴ Anselma, D.J.⁵ Monard, S.P.⁶ Segal, J.P.⁷ Thompson, D.A.⁸ Kajumo, F.⁹ Guo, Y.¹⁰ Moore, J.P.¹¹ Maddon, P.J.¹² Dragic, T.¹³

54
- 0033214087
- (1999) J. Biol. Chem. , vol.274 , pp. 28413-28419
- Wang, Z.¹ Lee, B.² Murray, J.L.³ Bonneau, F.⁴ Sun, Y.⁵ Schweickart, V.⁶ Zhang, T.⁷ Peiper, S.C.⁸

55
- 0029761071
- (1996) J. Biol. Chem. , vol.271 , pp. 19084-19092
- Monteclaro, F.S.¹ Charo, I.F.²

56
- 0028013658
- (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 1214-1218
- Siciliano, S.J.¹ Rollins, T.E.² DeMartino, J.³ Konteatis, Z.⁴ Malkowitz, L.⁵ Van Riper, G.⁶ Bondy, S.⁷ Rosen, H.⁸ Springer, M.S.⁹

57
- 0033025734
- (1999) J. Biol. Chem. , vol.274 , pp. 15757-15765
- Baranski, T.J.¹ Herzmark, P.² Lichtarge, O.³ Gerber, B.O.⁴ Trueheart, J.⁵ Meng, E.C.⁶ Iiri, T.⁷ Sheikh, S.P.⁸ Bourne, H.R.⁹

58
- 0008230228
- WO World Intellectual Property Organisation Patent WO9804554A1
- (1998)
- Naya, A.¹ Owada, Y.² Saeki, T.³ Ohwaki, K.⁴ Iwasawa, Y.⁵

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