Strategies for designing GPCR-focused libraries and screening sets

Current Opinion in Drug Discovery and Development

Volumn 7, Issue 3, 2004, Pages 325-333

  Jimonet, Patrick ^a   Jäger, Robert ^b  

^a SANOFI   (France)

^b SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Chemogenomics; Database; G protein coupled receptors; Homology model; Library design; Screening set

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LIGAND; RHODOPSIN;

COMBINATORIAL LIBRARY; CRYSTAL STRUCTURE; DATA BASE; DRUG DESIGN; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; KNOWLEDGE; MEDICAL INFORMATICS; PHYSICAL CHEMISTRY; REVIEW; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; BINDING SITE; CHEMICAL STRUCTURE; COMBINATORIAL CHEMISTRY; METABOLISM; METHODOLOGY;

BINDING SITES; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG DESIGN; LIGANDS; MODELS, MOLECULAR; RECEPTORS, G-PROTEIN-COUPLED; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4043107079     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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