A novel chemogenomics knowledge-based ligand design strategy - Application to G protein-coupled receptors

Quantitative Structure-Activity Relationships

Volumn 20, Issue 2, 2001, Pages 115-123

  Jacoby, Edgar ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Bioinformatics; Cheminformatics; Combinatorial chemistry; Lead finding; Reverse pharmacology

Indexed keywords

ACTIVATION ANALYSIS; BINDING SITES; BIOCHIPS; BIOINFORMATICS; KNOWLEDGE BASED SYSTEMS;

BINDING-SITES; CHEMINFORMATICS; CHEMOGENOMICS; COMBINATORIAL CHEMISTRY; DESIGN STRATEGIES; KNOWLEDGE BASED; LEAD-FINDING; LIGAND DESIGN; REVERSE PHARMACOLOGY; SEQUENCE SPACE;

LIGANDS;

1,4 BIS(1,4 BENZODIOXAN 2 YL METHYL)PIPERAZINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ADIR 1; AHP 1; AHP 2; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ASAHI 1; ASAHI 2; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CLOZAPINE; DOPAMINE RECEPTOR BLOCKING AGENT; G PROTEIN COUPLED RECEPTOR; JANSSEN 1; KETANSERIN; KISSEI 1; MEMBRANE RECEPTOR; MUSCARINIC AGENT; PROPANOL; RO 16814; SANOFI 1; SEROTONIN 1 RECEPTOR; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 5 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; DRUG BINDING; DRUG STRUCTURE; HUMAN; INFORMATION SCIENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

EID: 0034878886     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3838(200107)20:2<115::AID-QSAR115>3.0.CO;2-V     Document Type: Article

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