메뉴 건너뛰기




Volumn 23, Issue 2, 2005, Pages 103-108

Structural genomics of GPCRs

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL COMPOUNDS; CRYSTALLIZATION; CRYSTALLOGRAPHY; DRUG PRODUCTS; GENES; MOLECULAR STRUCTURE; PURIFICATION;

EID: 12344250438     PISSN: 01677799     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibtech.2004.12.006     Document Type: Review
Times cited : (84)

References (39)
  • 1
    • 0035213854 scopus 로고    scopus 로고
    • Patent status of the therapeutically important G protein-coupled receptors
    • W.B. Vanti Patent status of the therapeutically important G protein-coupled receptors Exp. Opin. Ther. Patents 11 2001 1861 1887
    • (2001) Exp. Opin. Ther. Patents , vol.11 , pp. 1861-1887
    • Vanti, W.B.1
  • 2
    • 0036729484 scopus 로고    scopus 로고
    • Seven-transmembrane receptors
    • K.L. Pierce Seven-transmembrane receptors Nat. Rev. Cell Mol. Biol. 3 2002 639 650
    • (2002) Nat. Rev. Cell Mol. Biol. , vol.3 , pp. 639-650
    • Pierce, K.L.1
  • 3
    • 0033118334 scopus 로고    scopus 로고
    • Molecular tinkering of G protein-coupled receptors: An evolutionary success
    • J. Bockaert, and J.P. Pin Molecular tinkering of G protein-coupled receptors: an evolutionary success EMBO J. 18 1999 1723 1729
    • (1999) EMBO J. , vol.18 , pp. 1723-1729
    • Bockaert, J.1    Pin, J.P.2
  • 4
    • 0031692337 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases
    • J.A. Pitcher G protein-coupled receptor kinases Annu. Rev. Biochem. 67 1998 653 692
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 653-692
    • Pitcher, J.A.1
  • 5
    • 0034464742 scopus 로고    scopus 로고
    • Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
    • U. Gether Uncovering molecular mechanisms involved in activation of G protein-coupled receptors Endocr. Rev. 21 2000 90 113
    • (2000) Endocr. Rev. , vol.21 , pp. 90-113
    • Gether, U.1
  • 6
    • 0031984517 scopus 로고    scopus 로고
    • The many faces of G protein signalling
    • H.E. Hamm The many faces of G protein signalling J. Biol. Chem. 273 1998 669 672
    • (1998) J. Biol. Chem. , vol.273 , pp. 669-672
    • Hamm, H.E.1
  • 7
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor
    • Y. Feng HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor Science 272 1996 872 877
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1
  • 8
    • 0034604451 scopus 로고    scopus 로고
    • Crystal structure of rhodopsin: A G protein-coupled receptor
    • K. Palczewski Crystal structure of rhodopsin: A G protein-coupled receptor Science 289 2000 739 745
    • (2000) Science , vol.289 , pp. 739-745
    • Palczewski, K.1
  • 9
    • 1642377401 scopus 로고    scopus 로고
    • Max Planck Institute of Biophysics, Frankfurt, Germany.
    • Michel, H. Membrane proteins of known structure. Max Planck Institute of Biophysics, Frankfurt, Germany. http://www.mpibp-frankfurt.mpg.de/michel/public/ memprotstruct.html
    • Membrane Proteins of Known Structure
    • Michel, H.1
  • 10
    • 0031008165 scopus 로고    scopus 로고
    • Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor
    • N.E. David Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor J. Biol. Chem. 272 1997 15553 15561
    • (1997) J. Biol. Chem. , vol.272 , pp. 15553-15561
    • David, N.E.1
  • 11
    • 0032081297 scopus 로고    scopus 로고
    • The human D1A dopamine receptor: Heterologous expression in Saccharomyces cerevisiae and purification of the functional receptor
    • B. Andersen, and R.C. Stevens The human D1A dopamine receptor: heterologous expression in Saccharomyces cerevisiae and purification of the functional receptor Protein Expr. Purif. 13 1998 111 119
    • (1998) Protein Expr. Purif. , vol.13 , pp. 111-119
    • Andersen, B.1    Stevens, R.C.2
  • 12
    • 0028174726 scopus 로고
    • Expression of the human D2S dopamine receptor in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe: A comparative study
    • P. Sander Expression of the human D2S dopamine receptor in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe: a comparative study FEBS Lett. 344 1994 41 46
    • (1994) FEBS Lett. , vol.344 , pp. 41-46
    • Sander, P.1
  • 13
    • 0032521005 scopus 로고    scopus 로고
    • Comparative biochemical and pharmacological characterization of the mouse 5-HT5A 5-hydroxytryptamine receptor and the human beta2-adrenergic receptor produced in the methylotrophic yeast Pichia pastoris
    • H.M. Weiss Comparative biochemical and pharmacological characterization of the mouse 5-HT5A 5-hydroxytryptamine receptor and the human beta2-adrenergic receptor produced in the methylotrophic yeast Pichia pastoris Biochem. J. 330 1998 1137 1147
    • (1998) Biochem. J. , vol.330 , pp. 1137-1147
    • Weiss, H.M.1
  • 14
    • 0028125669 scopus 로고
    • Expression and solubilization of a recombinant human neurokinin-1 receptor in insect cells
    • K.E. Mazina Expression and solubilization of a recombinant human neurokinin-1 receptor in insect cells J. Recept. Res. 14 1994 63 73
    • (1994) J. Recept. Res. , vol.14 , pp. 63-73
    • Mazina, K.E.1
  • 15
    • 4043130413 scopus 로고    scopus 로고
    • Generation of model cell lines expressing recombinant G protein-coupled receptors
    • E. Hermans Generation of model cell lines expressing recombinant G protein-coupled receptors Methods Mol. Biol. 259 2004 137 154
    • (2004) Methods Mol. Biol. , vol.259 , pp. 137-154
    • Hermans, E.1
  • 16
    • 0037109080 scopus 로고    scopus 로고
    • Structure and function in rhodopsin: A tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants
    • P.J. Reeves Structure and function in rhodopsin: a tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants Proc. Natl. Acad. Sci. U. S. A. 99 2002 13413 13418
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 13413-13418
    • Reeves, P.J.1
  • 17
    • 0033831644 scopus 로고    scopus 로고
    • Adenovirus vectors for high-efficiency gene transfer into mammalian cells
    • F.L. Graham Adenovirus vectors for high-efficiency gene transfer into mammalian cells Immunol. Today 21 2000 426 428
    • (2000) Immunol. Today , vol.21 , pp. 426-428
    • Graham, F.L.1
  • 18
    • 0029148618 scopus 로고
    • Stringent chemical and thermal regulation of recombinant gene expression by vaccinia virus vectors in mammalian cells
    • G.A. Ward Stringent chemical and thermal regulation of recombinant gene expression by vaccinia virus vectors in mammalian cells Proc. Natl. Acad. Sci. U. S. A. 92 1995 6773 6777
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 6773-6777
    • Ward, G.A.1
  • 19
    • 0037450521 scopus 로고    scopus 로고
    • Semliki Forest virus vectors for rapid high-level expression of integral membrane proteins
    • K. Lundstrom Semliki Forest virus vectors for rapid high-level expression of integral membrane proteins Biochim. Biophys. Acta 1610 2003 90 96
    • (2003) Biochim. Biophys. Acta , vol.1610 , pp. 90-96
    • Lundstrom, K.1
  • 20
    • 0024297305 scopus 로고
    • A continuous cell-free translation system capable of producing polypeptides in high yield
    • A.S. Spirin A continuous cell-free translation system capable of producing polypeptides in high yield Science 242 1988 1162 1164
    • (1988) Science , vol.242 , pp. 1162-1164
    • Spirin, A.S.1
  • 21
    • 0020475570 scopus 로고
    • Three-dimensional crystals of a membrane protein complex. The photosynthetic reaction centre from Rhodopseudomonas viridis
    • H. Michel Three-dimensional crystals of a membrane protein complex. The photosynthetic reaction centre from Rhodopseudomonas viridis J. Mol. Biol. 158 1982 567 572
    • (1982) J. Mol. Biol. , vol.158 , pp. 567-572
    • Michel, H.1
  • 22
    • 0028991525 scopus 로고
    • Fv fragment-mediated crystallization of the membrane protein bacterial cytochrome c oxidase
    • C. Ostermeier Fv fragment-mediated crystallization of the membrane protein bacterial cytochrome c oxidase Nat. Struct. Biol. 2 1995 842 846
    • (1995) Nat. Struct. Biol. , vol.2 , pp. 842-846
    • Ostermeier, C.1
  • 23
    • 0029992660 scopus 로고    scopus 로고
    • Lipidic cubic phases: A novel concept for the crystallization of membrane proteins
    • E.M. Landau, and J.P. Rosenbusch Lipidic cubic phases: a novel concept for the crystallization of membrane proteins Proc. Natl. Acad. Sci. U. S. A. 93 1996 14532 14535
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 14532-14535
    • Landau, E.M.1    Rosenbusch, J.P.2
  • 24
    • 0037351720 scopus 로고    scopus 로고
    • Structural genomics of membrane proteins
    • Y. Kyogoku Structural genomics of membrane proteins Acc. Chem. Res. 36 2003 199 206
    • (2003) Acc. Chem. Res. , vol.36 , pp. 199-206
    • Kyogoku, Y.1
  • 25
    • 0038159530 scopus 로고    scopus 로고
    • Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes
    • Y. Liang Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes J. Biol. Chem. 278 2003 21655 21662
    • (2003) J. Biol. Chem. , vol.278 , pp. 21655-21662
    • Liang, Y.1
  • 26
    • 0035066331 scopus 로고    scopus 로고
    • Structure of outer membrane protein a transmembrane domain by NMR spectroscopy
    • A. Arora Structure of outer membrane protein A transmembrane domain by NMR spectroscopy Nat. Struct. Biol. 8 2001 334 338
    • (2001) Nat. Struct. Biol. , vol.8 , pp. 334-338
    • Arora, A.1
  • 27
    • 0141703292 scopus 로고    scopus 로고
    • The conformation of neurotensin bound to its G protein-coupled receptor
    • S. Luca The conformation of neurotensin bound to its G protein-coupled receptor Proc. Natl. Acad. Sci. U. S. A. 100 2003 10706 10711
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 10706-10711
    • Luca, S.1
  • 28
    • 12244292640 scopus 로고    scopus 로고
    • Purification and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli
    • H.M. Weiss, and R. Grisshammer Purification and characterization of the human adenosine A2a receptor functionally expressed in Escherichia coli Eur. J. Biochem. 269 2002 82 92
    • (2002) Eur. J. Biochem. , vol.269 , pp. 82-92
    • Weiss, H.M.1    Grisshammer, R.2
  • 29
    • 0037648337 scopus 로고    scopus 로고
    • Structure-based analysis of GPCR function: Conformational adaptation of both agonist and receptor upon leukotriene B4 binding to recombinant BLT1
    • J-L. Baneres Structure-based analysis of GPCR function: Conformational adaptation of both agonist and receptor upon leukotriene B4 binding to recombinant BLT1 J. Mol. Biol. 329 2003 801 814
    • (2003) J. Mol. Biol. , vol.329 , pp. 801-814
    • Baneres, J.-L.1
  • 30
    • 0035671430 scopus 로고    scopus 로고
    • Solubilization and purification of the human ETB endothelin receptor produced by high-level fermentation in Pichia pastoris
    • H. Schiller Solubilization and purification of the human ETB endothelin receptor produced by high-level fermentation in Pichia pastoris Receptors Channels 7 2001 453 469
    • (2001) Receptors Channels , vol.7 , pp. 453-469
    • Schiller, H.1
  • 31
    • 0029959373 scopus 로고    scopus 로고
    • Purification and reconstitution of a recombinant human neurokinin-1 receptor
    • K.E. Mazzina Purification and reconstitution of a recombinant human neurokinin-1 receptor J. Recept. Signal Transduct. Res. 16 1996 191 207
    • (1996) J. Recept. Signal Transduct. Res. , vol.16 , pp. 191-207
    • Mazzina, K.E.1
  • 32
    • 0037109074 scopus 로고    scopus 로고
    • Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line
    • P.J. Reeves Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line Proc. Natl. Acad. Sci. U. S. A. 99 2002 13419 13424
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 13419-13424
    • Reeves, P.J.1
  • 33
    • 0035860530 scopus 로고    scopus 로고
    • Recombinant Semliki Forest virus for over-expression and functional characterisation of the histamine H2 receptor in mammalian cells
    • M. Hoffmann Recombinant Semliki Forest virus for over-expression and functional characterisation of the histamine H2 receptor in mammalian cells Eur. J. Pharmacol. 427 2001 105 114
    • (2001) Eur. J. Pharmacol. , vol.427 , pp. 105-114
    • Hoffmann, M.1
  • 34
    • 0033230397 scopus 로고    scopus 로고
    • Heterologous gene expression in a membrane-protein-specific system
    • G.J. Turner Heterologous gene expression in a membrane-protein-specific system Protein Expr. Purif. 17 1999 312 323
    • (1999) Protein Expr. Purif. , vol.17 , pp. 312-323
    • Turner, G.J.1
  • 35
    • 0037450575 scopus 로고    scopus 로고
    • Lactococcus lactis as host for overproduction of functional membrane proteins
    • E.R.S. Kunji Lactococcus lactis as host for overproduction of functional membrane proteins Biochim. Biophys. Acta 1610 2003 97 108
    • (2003) Biochim. Biophys. Acta , vol.1610 , pp. 97-108
    • Kunji, E.R.S.1
  • 36
    • 0026564303 scopus 로고
    • Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide
    • X.M. Guan Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide J. Biol. Chem. 267 1992 21995 21998
    • (1992) J. Biol. Chem. , vol.267 , pp. 21995-21998
    • Guan, X.M.1
  • 37
    • 0026647938 scopus 로고
    • Molecular cloning of a serotonin receptor from human brain (5HT1E): A fifth 5HT1-like subtype
    • G. Mc Allister Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype Proc. Natl. Acad. Sci. U. S. A. 89 1992 5517 5521
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 5517-5521
    • Mc Allister, G.1
  • 38
    • 0024410591 scopus 로고
    • Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation
    • C.M. Fraser Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation J. Biol. Chem. 264 1989 11754 11761
    • (1989) J. Biol. Chem. , vol.264 , pp. 11754-11761
    • Fraser, C.M.1
  • 39
    • 0027966894 scopus 로고
    • High-level expression of the human neurokinin-1 receptor in mammalian cell lines using the Semliki Forest virus expression system
    • K. Lundstrom High-level expression of the human neurokinin-1 receptor in mammalian cell lines using the Semliki Forest virus expression system Eur. J. Biochem. 224 1994 917 921
    • (1994) Eur. J. Biochem. , vol.224 , pp. 917-921
    • Lundstrom, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.