-
1
-
-
0036729484
-
Seven-transmembrane receptors
-
Pierce K.L., et al. Seven-transmembrane receptors. Nat. Rev. Mol. Cell Biol. 3:2002;639-650
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 639-650
-
-
Pierce, K.L.1
-
2
-
-
0038024615
-
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
-
Fredriksson R., et al. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol. Pharmacol. 63:2003;1256-1272
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 1256-1272
-
-
Fredriksson, R.1
-
3
-
-
0028909714
-
Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: Structure and function
-
Gudermann T., et al. Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function. J. Mol. Med. 73:1995;51-63
-
(1995)
J. Mol. Med.
, vol.73
, pp. 51-63
-
-
Gudermann, T.1
-
5
-
-
84910491966
-
Observations on the physiological action of extracts of the supra-renal bodies
-
Langley J.N. Observations on the physiological action of extracts of the supra-renal bodies. J. Physiol. (Lond.). 17:1901;231-256
-
(1901)
J. Physiol. (Lond.)
, vol.17
, pp. 231-256
-
-
Langley, J.N.1
-
6
-
-
0013679543
-
On some physiological actions of ergot
-
Dale H.H. On some physiological actions of ergot. J. Physiol. (Lond.). 34:1906;163-206
-
(1906)
J. Physiol. (Lond.)
, vol.34
, pp. 163-206
-
-
Dale, H.H.1
-
8
-
-
3242799458
-
Cyclic AMP
-
G.A. et al. Robison. Academic Press
-
Sutherland E.W. Cyclic AMP. Robison G.A.,, et al. An Introduction. 1971;5-13 Academic Press
-
(1971)
An Introduction
, pp. 5-13
-
-
Sutherland, E.W.1
-
9
-
-
0014409394
-
An adenosine 3′,5′-monophosphate-dependent protein kinase from rabbit skeletal muscle
-
Walsh D.A., et al. An adenosine 3′,5′-monophosphate-dependent protein kinase from rabbit skeletal muscle. J. Biol. Chem. 243:1968;3763-3765
-
(1968)
J. Biol. Chem.
, vol.243
, pp. 3763-3765
-
-
Walsh, D.A.1
-
10
-
-
0015239313
-
The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action
-
Rodbell M., et al. The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action. J. Biol. Chem. 246:1971;1877-1882
-
(1971)
J. Biol. Chem.
, vol.246
, pp. 1877-1882
-
-
Rodbell, M.1
-
11
-
-
0017757555
-
Resolution of some components of adenylate cyclase necessary for catalytic activity
-
Ross E.M., Gilman A.G. Resolution of some components of adenylate cyclase necessary for catalytic activity. J. Biol. Chem. 252:1977;6966-6969
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 6966-6969
-
-
Ross, E.M.1
Gilman, A.G.2
-
12
-
-
0023062991
-
G proteins: Transducers of receptor-generated signals
-
Gilman A.G. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56:1987;615-649
-
(1987)
Annu. Rev. Biochem.
, vol.56
, pp. 615-649
-
-
Gilman, A.G.1
-
13
-
-
0015857085
-
Adrenergic receptors: A personal and practical view
-
Ahlquist R.P. Adrenergic receptors: a personal and practical view. Perspect. Biol. Med. 17:1973;119-122
-
(1973)
Perspect. Biol. Med.
, vol.17
, pp. 119-122
-
-
Ahlquist, R.P.1
-
14
-
-
0014197689
-
Adenyl cyclase as an adrenergic receptor
-
Robison G.A., et al. Adenyl cyclase as an adrenergic receptor. Ann. New York Acad. Sci. 139:1967;703-723
-
(1967)
Ann. New York Acad. Sci.
, vol.139
, pp. 703-723
-
-
Robison, G.A.1
-
15
-
-
0027522236
-
Functional architecture of the nicotinic acetylcholine receptor: A prototype of ligand-gated ion channels
-
Devillers-Thiery A., et al. Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels. J. Membr. Biol. 136:1993;97-112
-
(1993)
J. Membr. Biol.
, vol.136
, pp. 97-112
-
-
Devillers-Thiery, A.1
-
16
-
-
0025812324
-
Model systems for the study of seven-transmembrane-segment receptors
-
Dohlman H.G., et al. Model systems for the study of seven-transmembrane- segment receptors. Annu. Rev. Biochem. 60:1991;653-688
-
(1991)
Annu. Rev. Biochem.
, vol.60
, pp. 653-688
-
-
Dohlman, H.G.1
-
17
-
-
0345667770
-
β-Adrenergic receptors and rhodopsin: Shedding new light on an old subject
-
Lefkowitz R.J., et al. β-Adrenergic receptors and rhodopsin: shedding new light on an old subject. Trends Pharmacol. Sci. 7:1986;444-448
-
(1986)
Trends Pharmacol. Sci.
, vol.7
, pp. 444-448
-
-
Lefkowitz, R.J.1
-
18
-
-
0022558381
-
Cyclic GMP cascade of vision
-
Stryer L. Cyclic GMP cascade of vision. Annu. Rev. Neurosci. 9:1986;87-119
-
(1986)
Annu. Rev. Neurosci.
, vol.9
, pp. 87-119
-
-
Stryer, L.1
-
19
-
-
0017708049
-
Large-scale purification of the acetylcholine-receptor protein in its membrane-bound and detergent-extracted forms from Torpedo marmorata electric organ
-
Sobel A., et al. Large-scale purification of the acetylcholine-receptor protein in its membrane-bound and detergent-extracted forms from Torpedo marmorata electric organ. Eur. J. Biochem. 80:1977;215-224
-
(1977)
Eur. J. Biochem.
, vol.80
, pp. 215-224
-
-
Sobel, A.1
-
20
-
-
0024360756
-
Nobel lecture in physiology or medicine-1988. Drugs from emasculated hormones: The principle of syntopic antagonism
-
Black J. Nobel lecture in physiology or medicine-1988. Drugs from emasculated hormones: the principle of syntopic antagonism. In Vitro Cell. Dev. Biol. 25:1989;311-320
-
(1989)
In Vitro Cell. Dev. Biol.
, vol.25
, pp. 311-320
-
-
Black, J.1
-
22
-
-
0019137579
-
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor
-
De Lean A., et al. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. J. Biol. Chem. 255:1980;7108-7117
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 7108-7117
-
-
De Lean, A.1
-
23
-
-
0018862848
-
A quantitative analysis of beta-adrenergic receptor interactions: Resolution of high and low affinity states of the receptor by computer modeling of ligand binding data
-
Kent R.S., et al. A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data. Mol. Pharmacol. 17:1980;14-23
-
(1980)
Mol. Pharmacol.
, vol.17
, pp. 14-23
-
-
Kent, R.S.1
-
24
-
-
0016739036
-
Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (-)isoproterenol in vitro
-
Mickey J., et al. Subsensitivity of adenylate cyclase and decreased beta-adrenergic receptor binding after chronic exposure to (-)isoproterenol in vitro. J. Biol. Chem. 250:1975;5727-5729
-
(1975)
J. Biol. Chem.
, vol.250
, pp. 5727-5729
-
-
Mickey, J.1
-
25
-
-
0018770017
-
Affinity chromatography of the beta-adrenergic receptor
-
Caron M.G., et al. Affinity chromatography of the beta-adrenergic receptor. J. Biol. Chem. 254:1979;2923-2927
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 2923-2927
-
-
Caron, M.G.1
-
26
-
-
0019793551
-
Purification of the beta-adrenergic receptor. Identification of the hormone binding subunit
-
Shorr R.G., et al. Purification of the beta-adrenergic receptor. Identification of the hormone binding subunit. J. Biol. Chem. 256:1981;5820-5826
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 5820-5826
-
-
Shorr, R.G.1
-
27
-
-
0021160160
-
The mammalian beta 2-adrenergic receptor: Purification and characterization
-
Benovic J.L., et al. The mammalian beta 2-adrenergic receptor: purification and characterization. Biochemistry. 23:1984;4510-4518
-
(1984)
Biochemistry
, vol.23
, pp. 4510-4518
-
-
Benovic, J.L.1
-
28
-
-
0022971818
-
Purification and characterization of the human platelet alpha 2-adrenergic receptor
-
Regan J.W., et al. Purification and characterization of the human platelet alpha 2-adrenergic receptor. J. Biol. Chem. 261:1986;3894-3900
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 3894-3900
-
-
Regan, J.W.1
-
29
-
-
0023037070
-
Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit
-
Lomasney J.W., et al. Mammalian alpha 1-adrenergic receptor. Purification and characterization of the native receptor ligand binding subunit. J. Biol. Chem. 261:1986;7710-7716
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 7710-7716
-
-
Lomasney, J.W.1
-
30
-
-
0020503940
-
Reconstitution of beta-adrenergic receptors in lipid vesicles: Affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system
-
Cerione R.A., et al. Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. Proc. Natl. Acad. Sci. U. S. A. 80:1983;4899-4903
-
(1983)
Proc. Natl. Acad. Sci. U. S. A.
, vol.80
, pp. 4899-4903
-
-
Cerione, R.A.1
-
31
-
-
0021212048
-
Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit
-
Cerione R.A., et al. Reconstitution of a hormone-sensitive adenylate cyclase system. The pure beta-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit. J. Biol. Chem. 259:1984;9979-9982
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 9979-9982
-
-
Cerione, R.A.1
-
32
-
-
0022372997
-
Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins
-
May D.C., et al. Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins. J. Biol. Chem. 260:1985;15829-15833
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 15829-15833
-
-
May, D.C.1
-
33
-
-
0022485749
-
Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin
-
Dixon R.A., et al. Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin. Nature. 321:1986;75-79
-
(1986)
Nature
, vol.321
, pp. 75-79
-
-
Dixon, R.A.1
-
34
-
-
0023194433
-
Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions
-
Kobilka B.K., et al. Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. J. Biol. Chem. 262:1987;7321-7327
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 7321-7327
-
-
Kobilka, B.K.1
-
35
-
-
0023628340
-
Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor
-
Kobilka B.K., et al. Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor. Science. 238:1987;650-656
-
(1987)
Science
, vol.238
, pp. 650-656
-
-
Kobilka, B.K.1
-
36
-
-
0030742986
-
Structure of the m1 muscarinic acetylcholine receptor gene and its promoter
-
Pepitoni S., et al. Structure of the m1 muscarinic acetylcholine receptor gene and its promoter. J. Biol. Chem. 272:1997;17112-17117
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17112-17117
-
-
Pepitoni, S.1
-
37
-
-
0025193479
-
Human dopamine D1 receptor encoded by an intronless gene on chromosome 5
-
Sunahara R.K., et al. Human dopamine D1 receptor encoded by an intronless gene on chromosome 5. Nature. 347:1990;80-83
-
(1990)
Nature
, vol.347
, pp. 80-83
-
-
Sunahara, R.K.1
-
38
-
-
0020373509
-
Rhodopsin and bacteriorhodopsin: Structure-function relationships
-
Ovchinnikov Y.A. Rhodopsin and bacteriorhodopsin: structure-function relationships. FEBS Lett. 148:1982;179-191
-
(1982)
FEBS Lett.
, vol.148
, pp. 179-191
-
-
Ovchinnikov, Y.A.1
-
39
-
-
0020540263
-
The structure of bovine rhodopsin
-
Hargrave P.A., et al. The structure of bovine rhodopsin. Biophys. Struct. Mech. 9:1983;235-244
-
(1983)
Biophys. Struct. Mech.
, vol.9
, pp. 235-244
-
-
Hargrave, P.A.1
-
40
-
-
0016842810
-
Three-dimensional model of purple membrane obtained by electron microscopy
-
Henderson R., Unwin P.N. Three-dimensional model of purple membrane obtained by electron microscopy. Nature. 257:1975;28-32
-
(1975)
Nature
, vol.257
, pp. 28-32
-
-
Henderson, R.1
Unwin, P.N.2
-
41
-
-
0023244963
-
A family of receptors coupled to guanine nucleotide regulatory proteins
-
Dohlman H.G., et al. A family of receptors coupled to guanine nucleotide regulatory proteins. Biochemistry. 26:1987;2657-2664
-
(1987)
Biochemistry
, vol.26
, pp. 2657-2664
-
-
Dohlman, H.G.1
-
42
-
-
0001661176
-
Cloning of the cDNA for the human beta 1-adrenergic receptor
-
Frielle T., et al. Cloning of the cDNA for the human beta 1-adrenergic receptor. Proc. Natl. Acad. Sci. U. S. A. 84:1987;7920-7924
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 7920-7924
-
-
Frielle, T.1
-
43
-
-
1842283729
-
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype
-
Regan J.W., et al. Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype. Proc. Natl. Acad. Sci. U. S. A. 85:1988;6301-6305
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 6301-6305
-
-
Regan, J.W.1
-
44
-
-
0001563379
-
Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor
-
Cotecchia S., et al. Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor. Proc. Natl. Acad. Sci. U. S. A. 85:1988;7159-7163
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 7159-7163
-
-
Cotecchia, S.1
-
45
-
-
0025349214
-
Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype
-
Schwinn D.A., et al. Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype. J. Biol. Chem. 265:1990;8183-8189
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 8183-8189
-
-
Schwinn, D.A.1
-
46
-
-
0025279114
-
Expansion of the alpha 2-adrenergic receptor family: Cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2
-
Lomasney J.W., et al. Expansion of the alpha 2-adrenergic receptor family: cloning and characterization of a human alpha 2-adrenergic receptor subtype, the gene for which is located on chromosome 2. Proc. Natl. Acad. Sci. U. S. A. 87:1990;5094-5098
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 5094-5098
-
-
Lomasney, J.W.1
-
47
-
-
0025822139
-
Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor
-
Lomasney J.W., et al. Molecular cloning and expression of the cDNA for the alpha 1A-adrenergic receptor. J. Biol. Chem. 266:1991;6365-6369
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 6365-6369
-
-
Lomasney, J.W.1
-
49
-
-
0023260731
-
Molecular distinction between muscarinic acetylcholine receptor subtypes
-
Fukuda K., et al. Molecular distinction between muscarinic acetylcholine receptor subtypes. Nature. 327:1987;623-625
-
(1987)
Nature
, vol.327
, pp. 623-625
-
-
Fukuda, K.1
-
50
-
-
0023636772
-
CDNA cloning of bovine substance-K receptor through oocyte expression system
-
Masu Y., et al. cDNA cloning of bovine substance-K receptor through oocyte expression system. Nature. 329:1987;836-838
-
(1987)
Nature
, vol.329
, pp. 836-838
-
-
Masu, Y.1
-
51
-
-
0023643263
-
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
-
Kobilka B.K., et al. An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins. Nature. 329:1987;75-79
-
(1987)
Nature
, vol.329
, pp. 75-79
-
-
Kobilka, B.K.1
-
52
-
-
0023786564
-
The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor
-
Fargin A., et al. The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor. Nature. 335:1988;358-360
-
(1988)
Nature
, vol.335
, pp. 358-360
-
-
Fargin, A.1
-
53
-
-
0025825726
-
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
-
Buck L., Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell. 65:1991;175-187
-
(1991)
Cell
, vol.65
, pp. 175-187
-
-
Buck, L.1
Axel, R.2
-
54
-
-
0026770487
-
Mutagenesis of the beta 2-adrenergic receptor: How structure elucidates function
-
Ostrowski J., et al. Mutagenesis of the beta 2-adrenergic receptor: how structure elucidates function. Annu. Rev. Pharmacol. Toxicol. 32:1992;167-183
-
(1992)
Annu. Rev. Pharmacol. Toxicol.
, vol.32
, pp. 167-183
-
-
Ostrowski, J.1
-
55
-
-
0028289513
-
Structure and function of G protein-coupled receptors
-
Strader C.D., et al. Structure and function of G protein-coupled receptors. Annu. Rev. Biochem. 63:1994;101-132
-
(1994)
Annu. Rev. Biochem.
, vol.63
, pp. 101-132
-
-
Strader, C.D.1
-
56
-
-
0024826133
-
Molecular cloning of the thyrotropin receptor
-
Parmentier M., et al. Molecular cloning of the thyrotropin receptor. Science. 246:1989;1620-1622
-
(1989)
Science
, vol.246
, pp. 1620-1622
-
-
Parmentier, M.1
-
57
-
-
0026035523
-
Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
-
Vu T.K., et al. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell. 64:1991;1057-1068
-
(1991)
Cell
, vol.64
, pp. 1057-1068
-
-
Vu, T.K.1
-
58
-
-
0023889603
-
Chimeric alpha 2-,beta 2-adrenergic receptors: Delineation of domains involved in effector coupling and ligand binding specificity
-
Kobilka B.K., et al. Chimeric alpha 2-,beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity. Science. 240:1988;1310-1316
-
(1988)
Science
, vol.240
, pp. 1310-1316
-
-
Kobilka, B.K.1
-
59
-
-
0026575003
-
Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis
-
Cotecchia S., et al. Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis. J. Biol. Chem. 267:1992;1633-1639
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1633-1639
-
-
Cotecchia, S.1
-
60
-
-
0026592357
-
Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation
-
Kjelsberg M.A., et al. Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation. J. Biol. Chem. 267:1992;1430-1433
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 1430-1433
-
-
Kjelsberg, M.A.1
-
62
-
-
0001169515
-
Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins
-
Costa T., Herz A. Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins. Proc. Natl. Acad. Sci. U. S. A. 86:1989;7321-7325
-
(1989)
Proc. Natl. Acad. Sci. U. S. A.
, vol.86
, pp. 7321-7325
-
-
Costa, T.1
Herz, A.2
-
63
-
-
0028987954
-
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor
-
Bond R.A., et al. Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor. Nature. 374:1995;272-276
-
(1995)
Nature
, vol.374
, pp. 272-276
-
-
Bond, R.A.1
-
64
-
-
0019956634
-
Light-dependent phosphorylation of rhodopsin: Number of phosphorylation sites
-
Wilden U., Kuhn H. Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites. Biochemistry. 21:1982;3014-3022
-
(1982)
Biochemistry
, vol.21
, pp. 3014-3022
-
-
Wilden, U.1
Kuhn, H.2
-
65
-
-
0020620777
-
Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor
-
Stadel J.M., et al. Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. Proc. Natl. Acad. Sci. U. S. A. 80:1983;3173-3177
-
(1983)
Proc. Natl. Acad. Sci. U. S. A.
, vol.80
, pp. 3173-3177
-
-
Stadel, J.M.1
-
66
-
-
0018119642
-
Light-dependent phosphorylation of rhodopsin. Purification and properties of rhodopsin kinase
-
Shichi H., Somers R.L. Light-dependent phosphorylation of rhodopsin. Purification and properties of rhodopsin kinase. J. Biol. Chem. 253:1978;7040-7046
-
(1978)
J. Biol. Chem.
, vol.253
, pp. 7040-7046
-
-
Shichi, H.1
Somers, R.L.2
-
67
-
-
0022257530
-
Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein
-
Benovic J.L., et al. Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein. J. Biol. Chem. 260:1985;7094-7101
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 7094-7101
-
-
Benovic, J.L.1
-
68
-
-
0344812247
-
Beta-adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor
-
Benovic J.L., et al. Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc. Natl. Acad. Sci. U. S. A. 83:1986;2797-2801
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 2797-2801
-
-
Benovic, J.L.1
-
69
-
-
0000025689
-
Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments
-
Wilden U., et al. Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments. Proc. Natl. Acad. Sci. U. S. A. 83:1986;1174-1178
-
(1986)
Proc. Natl. Acad. Sci. U. S. A.
, vol.83
, pp. 1174-1178
-
-
Wilden, U.1
-
70
-
-
3242748011
-
Arrestin mediates ATP/ADP exchange and quench of cGMP phosphodiesterase activation
-
Zuckerman R., et al. Arrestin mediates ATP/ADP exchange and quench of cGMP phosphodiesterase activation. Invest. Ophthalmol. Vis. Sci. (Suppl.). 26:1985;45
-
(1985)
Invest. Ophthalmol. Vis. Sci. (Suppl.)
, vol.26
, pp. 45
-
-
Zuckerman, R.1
-
71
-
-
0023645178
-
Purification and characterization of the beta-adrenergic receptor kinase
-
Benovic J.L., et al. Purification and characterization of the beta-adrenergic receptor kinase. J. Biol. Chem. 262:1987;9026-9032
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 9026-9032
-
-
Benovic, J.L.1
-
72
-
-
0023515309
-
Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: Potential role of an analog of the retinal protein arrestin (48-kDa protein)
-
Benovic J.L., et al. Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). Proc. Natl. Acad. Sci. U. S. A. 84:1987;8879-8882
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 8879-8882
-
-
Benovic, J.L.1
-
73
-
-
0023433192
-
Primary and secondary structure of bovine retinal S antigen (48-kDa protein)
-
Shinohara T., et al. Primary and secondary structure of bovine retinal S antigen (48-kDa protein). Proc. Natl. Acad. Sci. U. S. A. 84:1987;6975-6979
-
(1987)
Proc. Natl. Acad. Sci. U. S. A.
, vol.84
, pp. 6975-6979
-
-
Shinohara, T.1
-
74
-
-
0025352299
-
Beta-Arrestin: A protein that regulates beta-adrenergic receptor function
-
Lohse M.J., et al. beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science. 248:1990;1547-1550
-
(1990)
Science
, vol.248
, pp. 1547-1550
-
-
Lohse, M.J.1
-
75
-
-
0026730336
-
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family
-
Attramadal H., et al. Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family. J. Biol. Chem. 267:1992;17882-17890
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17882-17890
-
-
Attramadal, H.1
-
76
-
-
0022641020
-
Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase
-
Benovic J.L., et al. Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase. Nature. 321:1986;869-872
-
(1986)
Nature
, vol.321
, pp. 869-872
-
-
Benovic, J.L.1
-
77
-
-
0024412926
-
Beta-adrenergic receptor kinase: Primary structure delineates a multigene family
-
Benovic J.L., et al. Beta-adrenergic receptor kinase: primary structure delineates a multigene family. Science. 246:1989;235-240
-
(1989)
Science
, vol.246
, pp. 235-240
-
-
Benovic, J.L.1
-
78
-
-
0025987010
-
The receptor kinase family: Primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase
-
Lorenz W., et al. The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase. Proc. Natl. Acad. Sci. U. S. A. 88:1991;8715-8719
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 8715-8719
-
-
Lorenz, W.1
-
79
-
-
0027194487
-
G protein-coupled receptor kinases
-
Lefkowitz R.J. G protein-coupled receptor kinases. Cell. 74:1993;409-412
-
(1993)
Cell
, vol.74
, pp. 409-412
-
-
Lefkowitz, R.J.1
-
80
-
-
0031692337
-
G protein-coupled receptor kinases
-
Pitcher J.A., et al. G protein-coupled receptor kinases. Annu. Rev. Biochem. 67:1998;653-692
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 653-692
-
-
Pitcher, J.A.1
-
81
-
-
0345118937
-
Non-visual GRKs: Are we seeing the whole picture?
-
Willets J.M., et al. Non-visual GRKs: are we seeing the whole picture? Trends Pharmacol. Sci. 24:2003;626-633
-
(2003)
Trends Pharmacol. Sci.
, vol.24
, pp. 626-633
-
-
Willets, J.M.1
-
82
-
-
0037223063
-
Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization
-
Kohout T.A., Lefkowitz R.J. Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization. Mol. Pharmacol. 63:2003;9-18
-
(2003)
Mol. Pharmacol.
, vol.63
, pp. 9-18
-
-
Kohout, T.A.1
Lefkowitz, R.J.2
-
83
-
-
0242721361
-
Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
-
Shenoy S.K., Lefkowitz R.J. Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem. J. 375:2003;503-515
-
(2003)
Biochem. J.
, vol.375
, pp. 503-515
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
84
-
-
0036499130
-
Arresting developments in heptahelical receptor signaling and regulation
-
Perry S.J., Lefkowitz R.J. Arresting developments in heptahelical receptor signaling and regulation. Trends Cell Biol. 12:2002;130-138
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 130-138
-
-
Perry, S.J.1
Lefkowitz, R.J.2
-
85
-
-
0035101820
-
Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
-
Ferguson S.S. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol. Rev. 53:2001;1-24
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 1-24
-
-
Ferguson, S.S.1
-
86
-
-
0035834428
-
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin
-
Shenoy S.K., et al. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science. 294:2001;1307-1313
-
(2001)
Science
, vol.294
, pp. 1307-1313
-
-
Shenoy, S.K.1
-
87
-
-
0033613938
-
β-Arrestin-dependent formation of β2-adrenergic receptor/Src kinase complexes and mitogenic signaling
-
Luttrell L.M., et al. β-arrestin-dependent formation of β2-adrenergic receptor/Src kinase complexes and mitogenic signaling. Science. 283:1999;655-661
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
-
88
-
-
0035956983
-
Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds
-
Luttrell L.M., et al. Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc. Natl. Acad. Sci. U. S. A. 98:2001;2449-2454
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 2449-2454
-
-
Luttrell, L.M.1
-
89
-
-
0037147145
-
Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
-
Sun Y., et al. Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J. Biol. Chem. 277:2002;49212-49219
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49212-49219
-
-
Sun, Y.1
-
90
-
-
0034711397
-
Beta-arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3
-
McDonald P.H., et al. Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science. 290:2000;1574-1577
-
(2000)
Science
, vol.290
, pp. 1574-1577
-
-
McDonald, P.H.1
-
91
-
-
0037166254
-
Alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression
-
Goel R., et al. alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression. J. Biol. Chem. 277:2002;18640-18648
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18640-18648
-
-
Goel, R.1
-
92
-
-
0347695992
-
Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis
-
Povsic T.J., et al. Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis. J. Biol. Chem. 278:2003;51334-51339
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51334-51339
-
-
Povsic, T.J.1
-
93
-
-
0033610892
-
Beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor
-
Lin F.T., et al. beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor. J. Biol. Chem. 273:1998;31640-31643
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 31640-31643
-
-
Lin, F.T.1
-
94
-
-
0037088585
-
Beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation
-
Tohgo A., et al. beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. J. Biol. Chem. 277:2002;9429-9436
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9429-9436
-
-
Tohgo, A.1
-
95
-
-
0037458614
-
The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
-
Tohgo A., et al. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. J. Biol. Chem. 278:2003;6258-6267
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6258-6267
-
-
Tohgo, A.1
-
96
-
-
0037188469
-
Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice
-
Fong A.M., et al. Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 99:2002;7478-7483
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 7478-7483
-
-
Fong, A.M.1
-
97
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K., et al. Crystal structure of rhodopsin: A G protein-coupled receptor. Science. 289:2000;739-745
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
-
98
-
-
0033574274
-
The 2.8 a crystal structure of visual arrestin: A model for arrestin's regulation
-
Hirsch J.A., et al. The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation. Cell. 97:1999;257-269
-
(1999)
Cell
, vol.97
, pp. 257-269
-
-
Hirsch, J.A.1
-
99
-
-
0037799206
-
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gbetagamma
-
Lodowski D.T., et al. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma. Science. 300:2003;1256-1262
-
(2003)
Science
, vol.300
, pp. 1256-1262
-
-
Lodowski, D.T.1
-
100
-
-
0036174608
-
Dimerization: An emerging concept for G protein-coupled receptor ontogeny and function
-
Angers S., et al. Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function. Annu. Rev. Pharmacol. Toxicol. 42:2002;409-435
-
(2002)
Annu. Rev. Pharmacol. Toxicol.
, vol.42
, pp. 409-435
-
-
Angers, S.1
-
101
-
-
0242352645
-
Continued discovery of ligands for G protein-coupled receptors
-
Lee D.K., et al. Continued discovery of ligands for G protein-coupled receptors. Life Sci. 74:2003;293-297
-
(2003)
Life Sci.
, vol.74
, pp. 293-297
-
-
Lee, D.K.1
-
102
-
-
0036174898
-
G protein-coupled receptor interacting proteins: Emerging roles in localization and signal transduction
-
Brady A.E., Limbird L.E. G protein-coupled receptor interacting proteins: emerging roles in localization and signal transduction. Cell. Signal. 14:2002;297-309
-
(2002)
Cell. Signal.
, vol.14
, pp. 297-309
-
-
Brady, A.E.1
Limbird, L.E.2
-
103
-
-
16044373004
-
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
-
Samson M., et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature. 382:1996;722-725
-
(1996)
Nature
, vol.382
, pp. 722-725
-
-
Samson, M.1
-
104
-
-
0142073817
-
Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure
-
Mialet Perez, J. et al. (2003) Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure. Nat. Med. 9, 1300-1305.
-
(2003)
Nat. Med.
, vol.9
, pp. 1300-1305
-
-
Mialet Perez, J.1
|