메뉴 건너뛰기




Volumn 24, Issue 2, 2006, Pages 381-405

Interactions of Volatile Anesthetics with Neurodegenerative-Disease-Associated Proteins

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN[1-40]; ATAXIN 1; BENZODIAZEPINE; HALOTHANE; HUNTINGTIN; HYPNOTIC AGENT; INHALATION ANESTHETIC AGENT; ISOFLURANE; PRION PROTEIN; PROPOFOL; TAU PROTEIN;

EID: 33747695707     PISSN: 08898537     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atc.2006.02.002     Document Type: Review
Times cited : (18)

References (112)
  • 1
    • 0042023711 scopus 로고    scopus 로고
    • Alzheimer disease in the US population: prevalence estimates using the 2000 census
    • Hebert L.E., Scherr P.A., Bienias J.L., et al. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol 60 8 (2003) 1119-1122
    • (2003) Arch Neurol , vol.60 , Issue.8 , pp. 1119-1122
    • Hebert, L.E.1    Scherr, P.A.2    Bienias, J.L.3
  • 2
    • 0030801772 scopus 로고    scopus 로고
    • Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society
    • Small G.W., Rabins P.V., Barry P.P., et al. Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society. JAMA 278 16 (1997) 1363-1371
    • (1997) JAMA , vol.278 , Issue.16 , pp. 1363-1371
    • Small, G.W.1    Rabins, P.V.2    Barry, P.P.3
  • 3
    • 0029937494 scopus 로고    scopus 로고
    • Epidemiology of Parkinson's disease
    • Tanner C.M., and Goldman S.M. Epidemiology of Parkinson's disease. Neurol Clin 14 2 (1996) 317-335
    • (1996) Neurol Clin , vol.14 , Issue.2 , pp. 317-335
    • Tanner, C.M.1    Goldman, S.M.2
  • 4
    • 0034885740 scopus 로고    scopus 로고
    • Evaluation of blink reflex results obtained from workers previously diagnosed with solvent-induced toxic encephalopathy
    • Albers J.W., Wald J.J., Trask C.L., et al. Evaluation of blink reflex results obtained from workers previously diagnosed with solvent-induced toxic encephalopathy. J Occup Environ Med 43 8 (2001) 713-722
    • (2001) J Occup Environ Med , vol.43 , Issue.8 , pp. 713-722
    • Albers, J.W.1    Wald, J.J.2    Trask, C.L.3
  • 5
    • 0032554547 scopus 로고    scopus 로고
    • Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction. [Erratum appears in Lancet 1998;351(9117):1742]
    • Moller J.T., Cluitmans P., Rasmussen L.S., et al. Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction. [Erratum appears in Lancet 1998;351(9117):1742]. Lancet 351 9106 (1998) 857-861
    • (1998) Lancet , vol.351 , Issue.9106 , pp. 857-861
    • Moller, J.T.1    Cluitmans, P.2    Rasmussen, L.S.3
  • 6
    • 0842348906 scopus 로고    scopus 로고
    • Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia
    • Nishikawa K., Nakayama M., Omote K., et al. Recovery characteristics and post-operative delirium after long-duration laparoscope-assisted surgery in elderly patients: propofol-based vs. sevoflurane-based anesthesia. Acta Anaesthesiol Scand 48 (2004) 162-168
    • (2004) Acta Anaesthesiol Scand , vol.48 , pp. 162-168
    • Nishikawa, K.1    Nakayama, M.2    Omote, K.3
  • 7
    • 0035075294 scopus 로고    scopus 로고
    • Exposure to anaesthetic agents, cognitive functioning and depressive symptomatology in the elderly
    • Ancelin M.L., de Roquefeuil G., Ledesert B., et al. Exposure to anaesthetic agents, cognitive functioning and depressive symptomatology in the elderly. Br J Psychiatry 178 (2001) 360-366
    • (2001) Br J Psychiatry , vol.178 , pp. 360-366
    • Ancelin, M.L.1    de Roquefeuil, G.2    Ledesert, B.3
  • 8
    • 18444363330 scopus 로고    scopus 로고
    • Postoperative cognitive dysfunction in middle-aged patients
    • Johnson T., Monk T., Rasmussen L.S., et al. Postoperative cognitive dysfunction in middle-aged patients. Anesthesiology 96 6 (2002) 1351-1357
    • (2002) Anesthesiology , vol.96 , Issue.6 , pp. 1351-1357
    • Johnson, T.1    Monk, T.2    Rasmussen, L.S.3
  • 9
    • 50449121132 scopus 로고
    • Adverse cerebral effects of anesthesia on old people
    • Bedford P.D. Adverse cerebral effects of anesthesia on old people. Lancet ii (1955) 259-263
    • (1955) Lancet , vol.ii , pp. 259-263
    • Bedford, P.D.1
  • 11
    • 0002796046 scopus 로고    scopus 로고
    • Epidemiology of Dementia and Alzheimer Disease
    • Terry R.D., Katzman R., Bick K.L., et al. (Eds), Lippincott Williams & Wilkins, Philadelphia
    • Kawas C.H., and Katzman R. Epidemiology of Dementia and Alzheimer Disease. In: Terry R.D., Katzman R., Bick K.L., et al. (Eds). Alzheimer Disease (1999), Lippincott Williams & Wilkins, Philadelphia 95-116
    • (1999) Alzheimer Disease , pp. 95-116
    • Kawas, C.H.1    Katzman, R.2
  • 12
    • 24144438172 scopus 로고    scopus 로고
    • Structure and morphology of the Alzheimer's amyloid fibril
    • Stromer T., and Serpell L.C. Structure and morphology of the Alzheimer's amyloid fibril. Microsc Res Tech 67 3-4 (2005) 210-217
    • (2005) Microsc Res Tech , vol.67 , Issue.3-4 , pp. 210-217
    • Stromer, T.1    Serpell, L.C.2
  • 13
    • 0033012737 scopus 로고    scopus 로고
    • Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein
    • Seabrook G.R., Smith D.W., Bowery B.J., et al. Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein. Neuropharmacol 38 3 (1999) 349-359
    • (1999) Neuropharmacol , vol.38 , Issue.3 , pp. 349-359
    • Seabrook, G.R.1    Smith, D.W.2    Bowery, B.J.3
  • 14
    • 0028018919 scopus 로고
    • Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene
    • Muller U., Cristina N., Li Z.W., et al. Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene. Cell 79 5 (1994) 755-765
    • (1994) Cell , vol.79 , Issue.5 , pp. 755-765
    • Muller, U.1    Cristina, N.2    Li, Z.W.3
  • 15
    • 0028988801 scopus 로고
    • beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
    • Zheng H., Jiang M., Trumbauer M.E., et al. beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell 81 4 (1995) 525-531
    • (1995) Cell , vol.81 , Issue.4 , pp. 525-531
    • Zheng, H.1    Jiang, M.2    Trumbauer, M.E.3
  • 16
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. [Erratum appears in Science 2002;297(5590):2209]
    • Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. [Erratum appears in Science 2002;297(5590):2209]. Science 297 5580 (2002) 353-356
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 17
    • 0002080057 scopus 로고    scopus 로고
    • The neuropathology of Alzheimer disease and the structural basis of its cognitive alterations
    • Terry R.D., Katzman R., Bick K.L., et al. (Eds), Lippincott Williams and Wilkins, Philadelphia
    • Terry R.D., Masliah E., and Hansen L.L. The neuropathology of Alzheimer disease and the structural basis of its cognitive alterations. In: Terry R.D., Katzman R., Bick K.L., et al. (Eds). Alzheimer Disease (1999), Lippincott Williams and Wilkins, Philadelphia 187-206
    • (1999) Alzheimer Disease , pp. 187-206
    • Terry, R.D.1    Masliah, E.2    Hansen, L.L.3
  • 18
    • 0035297712 scopus 로고    scopus 로고
    • Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?
    • Klein W.L., Krafft G.A., and Finch C.E. Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?. Trends Neurosci 24 4 (2001) 219-224
    • (2001) Trends Neurosci , vol.24 , Issue.4 , pp. 219-224
    • Klein, W.L.1    Krafft, G.A.2    Finch, C.E.3
  • 19
    • 0242668337 scopus 로고    scopus 로고
    • Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
    • Kayed R., Head E., Thompson J.L., et al. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300 5618 (2003) 486-489
    • (2003) Science , vol.300 , Issue.5618 , pp. 486-489
    • Kayed, R.1    Head, E.2    Thompson, J.L.3
  • 20
    • 2542455537 scopus 로고    scopus 로고
    • Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease
    • Klein W.L., Stine Jr. W.B., and Teplow D.B. Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease. Neurobiol Aging 25 5 (2004) 569-580
    • (2004) Neurobiol Aging , vol.25 , Issue.5 , pp. 569-580
    • Klein, W.L.1    Stine Jr., W.B.2    Teplow, D.B.3
  • 21
    • 33747686568 scopus 로고    scopus 로고
    • Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis
    • Accessed February 27, 2006
    • Glabe C.G., and Kayed R. Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis. Neurology (2005). Available at: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed &dopt=Abstract&list_uids=16361390&itool=iconabstr&query_ hl=13&itool=pubmed_docsum Accessed February 27, 2006
    • (2005) Neurology
    • Glabe, C.G.1    Kayed, R.2
  • 22
    • 11144243412 scopus 로고    scopus 로고
    • Modulation of neurodegeneration by molecular chaperones
    • Muchowski P.J., and Wacker J.L. Modulation of neurodegeneration by molecular chaperones. Nat Rev Neurosci 6 1 (2005) 11-22
    • (2005) Nat Rev Neurosci , vol.6 , Issue.1 , pp. 11-22
    • Muchowski, P.J.1    Wacker, J.L.2
  • 23
    • 13244267202 scopus 로고    scopus 로고
    • Mechanisms of suppression of α-synuclein neurotoxicity by geldanamycin in Drosophila
    • Auluck P.K., Meulener M.C., and Bonini N.M. Mechanisms of suppression of α-synuclein neurotoxicity by geldanamycin in Drosophila. J Biol Chem 280 4 (2005) 2873-2878
    • (2005) J Biol Chem , vol.280 , Issue.4 , pp. 2873-2878
    • Auluck, P.K.1    Meulener, M.C.2    Bonini, N.M.3
  • 24
    • 13544268706 scopus 로고    scopus 로고
    • Immunological and anti-chaperone therapeutic approaches for Alzheimer disease
    • Wisniewski T., and Frangione B. Immunological and anti-chaperone therapeutic approaches for Alzheimer disease. Brain Pathol 15 1 (2005) 72-77
    • (2005) Brain Pathol , vol.15 , Issue.1 , pp. 72-77
    • Wisniewski, T.1    Frangione, B.2
  • 25
    • 11444267243 scopus 로고    scopus 로고
    • Evaluation of the safety and immunogenicity of synthetic Abeta42 (AN1792) in patients with AD
    • Bayer A.J., Bullock R., Jones R.W., et al. Evaluation of the safety and immunogenicity of synthetic Abeta42 (AN1792) in patients with AD. Neurology 64 1 (2005) 94-101
    • (2005) Neurology , vol.64 , Issue.1 , pp. 94-101
    • Bayer, A.J.1    Bullock, R.2    Jones, R.W.3
  • 26
    • 4444362840 scopus 로고    scopus 로고
    • Current progress in beta-amyloid immunotherapy
    • Schenk D., Hagen M., and Seubert P. Current progress in beta-amyloid immunotherapy. Curr Opin Immunol 16 5 (2004) 599-606
    • (2004) Curr Opin Immunol , vol.16 , Issue.5 , pp. 599-606
    • Schenk, D.1    Hagen, M.2    Seubert, P.3
  • 27
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
    • Schenk D., Barbour R., Dunn W., et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400 6740 (1999) 173-177
    • (1999) Nature , vol.400 , Issue.6740 , pp. 173-177
    • Schenk, D.1    Barbour, R.2    Dunn, W.3
  • 28
    • 0033801852 scopus 로고    scopus 로고
    • Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease
    • Weiner H.L., Lemere C.A., Maron R., et al. Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease. Ann Neurol 48 4 (2000) 567-579
    • (2000) Ann Neurol , vol.48 , Issue.4 , pp. 567-579
    • Weiner, H.L.1    Lemere, C.A.2    Maron, R.3
  • 29
    • 0034700471 scopus 로고    scopus 로고
    • A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
    • Janus C., Pearson J., McLaurin J., et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408 6815 (2000) 979-982
    • (2000) Nature , vol.408 , Issue.6815 , pp. 979-982
    • Janus, C.1    Pearson, J.2    McLaurin, J.3
  • 30
    • 10044297055 scopus 로고    scopus 로고
    • Lifelong immunization with human beta-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging
    • Jensen M.T., Mottin M.D., Cracchiolo J.R., et al. Lifelong immunization with human beta-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging. Neuroscience 130 3 (2005) 667-684
    • (2005) Neuroscience , vol.130 , Issue.3 , pp. 667-684
    • Jensen, M.T.1    Mottin, M.D.2    Cracchiolo, J.R.3
  • 31
    • 3042692322 scopus 로고    scopus 로고
    • Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet
    • Lemere C.A., Beierschmitt A., Iglesias M., et al. Alzheimer's disease abeta vaccine reduces central nervous system abeta levels in a non-human primate, the Caribbean vervet. Am J Pathol 165 1 (2004) 283-297
    • (2004) Am J Pathol , vol.165 , Issue.1 , pp. 283-297
    • Lemere, C.A.1    Beierschmitt, A.2    Iglesias, M.3
  • 32
    • 0033835996 scopus 로고    scopus 로고
    • Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
    • Bard F., Cannon C., Barbour R., et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med 6 8 (2000) 916-919
    • (2000) Nat Med , vol.6 , Issue.8 , pp. 916-919
    • Bard, F.1    Cannon, C.2    Barbour, R.3
  • 33
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
    • DeMattos R.B., Bales K.R., Cummins D.J., et al. Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 98 15 (2001) 8850-8855
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.15 , pp. 8850-8855
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3
  • 34
    • 4043167747 scopus 로고    scopus 로고
    • Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
    • Oddo S., Billings L., Kesslak J.P., et al. Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron 43 3 (2004) 321-332
    • (2004) Neuron , vol.43 , Issue.3 , pp. 321-332
    • Oddo, S.1    Billings, L.2    Kesslak, J.P.3
  • 35
    • 0036852750 scopus 로고    scopus 로고
    • Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis
    • McLaurin J., Cecal R., Kierstead M.E., et al. Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis. Nat Med 8 11 (2002) 1263-1269
    • (2002) Nat Med , vol.8 , Issue.11 , pp. 1263-1269
    • McLaurin, J.1    Cecal, R.2    Kierstead, M.E.3
  • 36
    • 30344448543 scopus 로고    scopus 로고
    • A dynamic relationship between intracellular and extracellular pools of aβ
    • Oddo S., Caccamo A., Smith I., et al. A dynamic relationship between intracellular and extracellular pools of aβ. Am J Pathol 168 1 (2006) 184-194
    • (2006) Am J Pathol , vol.168 , Issue.1 , pp. 184-194
    • Oddo, S.1    Caccamo, A.2    Smith, I.3
  • 37
    • 84984755327 scopus 로고    scopus 로고
    • A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. [Erratum appears in Nature 2001;412(6847):660]
    • Morgan D., Diamond D.M., Gottschall P.E., et al. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. [Erratum appears in Nature 2001;412(6847):660]. Nature 408 6815 (2000) 982-985
    • (2000) Nature , vol.408 , Issue.6815 , pp. 982-985
    • Morgan, D.1    Diamond, D.M.2    Gottschall, P.E.3
  • 38
    • 0036703483 scopus 로고    scopus 로고
    • Reversible memory loss in a mouse transgenic model of Alzheimer's disease
    • Kotilinek L.A., Bacskai B., Westerman M., et al. Reversible memory loss in a mouse transgenic model of Alzheimer's disease. J Neurosci 22 15 (2002) 6331-6335
    • (2002) J Neurosci , vol.22 , Issue.15 , pp. 6331-6335
    • Kotilinek, L.A.1    Bacskai, B.2    Westerman, M.3
  • 39
    • 0002639884 scopus 로고    scopus 로고
    • Dosing in phase II trial of Alzheimer's vaccine suspended
    • Senior K. Dosing in phase II trial of Alzheimer's vaccine suspended. Lancet Neurol 1 1 (2002) 3
    • (2002) Lancet Neurol , vol.1 , Issue.1 , pp. 3
    • Senior, K.1
  • 40
    • 10744230547 scopus 로고    scopus 로고
    • Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
    • Orgogozo J.M., Gilman S., Dartigues J.F., et al. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology 61 1 (2003) 46-54
    • (2003) Neurology , vol.61 , Issue.1 , pp. 46-54
    • Orgogozo, J.M.1    Gilman, S.2    Dartigues, J.F.3
  • 41
    • 0037369507 scopus 로고    scopus 로고
    • Drugs targeting Alzheimer's disease: some things old and some things new
    • Michaelis M.L. Drugs targeting Alzheimer's disease: some things old and some things new. J Pharmacol Exp Ther 304 3 (2003) 897-904
    • (2003) J Pharmacol Exp Ther , vol.304 , Issue.3 , pp. 897-904
    • Michaelis, M.L.1
  • 42
    • 4344688011 scopus 로고    scopus 로고
    • Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization
    • De Felice F.G., Vieira M.N., Saraiva L.M., et al. Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization. FASEB J 18 12 (2004) 1366-1372
    • (2004) FASEB J , vol.18 , Issue.12 , pp. 1366-1372
    • De Felice, F.G.1    Vieira, M.N.2    Saraiva, L.M.3
  • 43
    • 0037044835 scopus 로고    scopus 로고
    • New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease
    • Lashuel H.A., Hartley D.M., Balakhaneh D., et al. New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease. J Biol Chem 277 45 (2002) 42881-42890
    • (2002) J Biol Chem , vol.277 , Issue.45 , pp. 42881-42890
    • Lashuel, H.A.1    Hartley, D.M.2    Balakhaneh, D.3
  • 44
    • 17044439021 scopus 로고    scopus 로고
    • Alzheimer's disease: Abeta, tau and synaptic dysfunction
    • LaFerla F.M., and Oddo S. Alzheimer's disease: Abeta, tau and synaptic dysfunction. Trends Mol Med 11 4 (2005) 170-176
    • (2005) Trends Mol Med , vol.11 , Issue.4 , pp. 170-176
    • LaFerla, F.M.1    Oddo, S.2
  • 47
    • 7044238416 scopus 로고    scopus 로고
    • Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs
    • Forman M.S., Trojanowski J.Q., and Lee V.M. Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 10 10 (2004) 1055-1063
    • (2004) Nat Med , vol.10 , Issue.10 , pp. 1055-1063
    • Forman, M.S.1    Trojanowski, J.Q.2    Lee, V.M.3
  • 48
    • 0035169488 scopus 로고    scopus 로고
    • Lewy body pathology in Alzheimer's disease
    • Kotzbauer P.T., Trojanowsk J.Q., and Lee V.M. Lewy body pathology in Alzheimer's disease. J Mol Neurosci 17 2 (2001) 225-232
    • (2001) J Mol Neurosci , vol.17 , Issue.2 , pp. 225-232
    • Kotzbauer, P.T.1    Trojanowsk, J.Q.2    Lee, V.M.3
  • 49
    • 0035409575 scopus 로고    scopus 로고
    • Alpha-synuclein and neurodegenerative diseases
    • Goedert M. Alpha-synuclein and neurodegenerative diseases. Nat Rev Neurosci 2 7 (2001) 492-501
    • (2001) Nat Rev Neurosci , vol.2 , Issue.7 , pp. 492-501
    • Goedert, M.1
  • 50
    • 2642514788 scopus 로고    scopus 로고
    • Alpha-synuclein: normal function and role in neurodegenerative diseases
    • Norris E.H., Giasson B.I., and Lee V.M. Alpha-synuclein: normal function and role in neurodegenerative diseases. Curr Top Dev Biol 60 (2004) 17-54
    • (2004) Curr Top Dev Biol , vol.60 , pp. 17-54
    • Norris, E.H.1    Giasson, B.I.2    Lee, V.M.3
  • 51
    • 14344263884 scopus 로고    scopus 로고
    • The role of alpha-synuclein in neurodegenerative diseases
    • Bennett M.C. The role of alpha-synuclein in neurodegenerative diseases. Pharmacol Ther 105 3 (2005) 311-331
    • (2005) Pharmacol Ther , vol.105 , Issue.3 , pp. 311-331
    • Bennett, M.C.1
  • 52
    • 0035834076 scopus 로고    scopus 로고
    • Beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
    • Masliah E., Rockenstein E., Veinbergs I., et al. Beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci USA 98 21 (2001) 12245-12250
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.21 , pp. 12245-12250
    • Masliah, E.1    Rockenstein, E.2    Veinbergs, I.3
  • 53
    • 0035943436 scopus 로고    scopus 로고
    • Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
    • Gotz J., Chen F., van Dorpe J., et al. Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science 293 5534 (2001) 1491-1495
    • (2001) Science , vol.293 , Issue.5534 , pp. 1491-1495
    • Gotz, J.1    Chen, F.2    van Dorpe, J.3
  • 54
    • 0037466656 scopus 로고    scopus 로고
    • Initiation and synergistic fibrillization of tau and alpha-synuclein
    • Giasson B.I., Forman M.S., Higuchi M., et al. Initiation and synergistic fibrillization of tau and alpha-synuclein. Science 300 5619 (2003) 636-640
    • (2003) Science , vol.300 , Issue.5619 , pp. 636-640
    • Giasson, B.I.1    Forman, M.S.2    Higuchi, M.3
  • 55
    • 2342556414 scopus 로고    scopus 로고
    • Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation
    • Kotzbauer P.T., Giasson B.I., Kravitz A.V., et al. Fibrillization of alpha-synuclein and tau in familial Parkinson's disease caused by the A53T alpha-synuclein mutation. Exp Neurol 187 2 (2004) 279-288
    • (2004) Exp Neurol , vol.187 , Issue.2 , pp. 279-288
    • Kotzbauer, P.T.1    Giasson, B.I.2    Kravitz, A.V.3
  • 56
    • 2342556413 scopus 로고    scopus 로고
    • Following the leader: fibrillization of alpha-synuclein and tau
    • Frasier M., and Wolozin B. Following the leader: fibrillization of alpha-synuclein and tau. Exp Neurol 187 2 (2004) 235-239
    • (2004) Exp Neurol , vol.187 , Issue.2 , pp. 235-239
    • Frasier, M.1    Wolozin, B.2
  • 57
    • 0034094873 scopus 로고    scopus 로고
    • Glutamine repeats and neurodegeneration
    • Zoghbi H.Y., and Orr H.T. Glutamine repeats and neurodegeneration. Annu Rev Neurosci 23 (2000) 217-247
    • (2000) Annu Rev Neurosci , vol.23 , pp. 217-247
    • Zoghbi, H.Y.1    Orr, H.T.2
  • 58
    • 9444267651 scopus 로고    scopus 로고
    • The state of the prion
    • Weissmann C. The state of the prion. Nat Rev Microbiol 2 11 (2004) 861-871
    • (2004) Nat Rev Microbiol , vol.2 , Issue.11 , pp. 861-871
    • Weissmann, C.1
  • 59
    • 0037368005 scopus 로고    scopus 로고
    • Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment
    • DeArmond S.J., and Prusiner S.B. Perspectives on prion biology, prion disease pathogenesis, and pharmacologic approaches to treatment. Clin Lab Med 23 1 (2003) 1-41
    • (2003) Clin Lab Med , vol.23 , Issue.1 , pp. 1-41
    • DeArmond, S.J.1    Prusiner, S.B.2
  • 60
  • 61
    • 0344944630 scopus 로고    scopus 로고
    • Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
    • Stefani M., and Dobson C.M. Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J Mol Med 81 11 (2003) 678-699
    • (2003) J Mol Med , vol.81 , Issue.11 , pp. 678-699
    • Stefani, M.1    Dobson, C.M.2
  • 62
    • 0347357617 scopus 로고    scopus 로고
    • Protein folding and misfolding
    • Dobson C.M. Protein folding and misfolding. Nature 426 6968 (2003) 884-890
    • (2003) Nature , vol.426 , Issue.6968 , pp. 884-890
    • Dobson, C.M.1
  • 63
    • 7944233158 scopus 로고    scopus 로고
    • Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases
    • Selkoe D.J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat Cell Biol 6 11 (2004) 1054-1061
    • (2004) Nat Cell Biol , vol.6 , Issue.11 , pp. 1054-1061
    • Selkoe, D.J.1
  • 64
    • 3843148352 scopus 로고    scopus 로고
    • Prefibrillar amyloid protein aggregates share common features of cytotoxicity
    • Bucciantini M., Calloni G., Chiti F., et al. Prefibrillar amyloid protein aggregates share common features of cytotoxicity. J Biol Chem 279 30 (2004) 31374-31382
    • (2004) J Biol Chem , vol.279 , Issue.30 , pp. 31374-31382
    • Bucciantini, M.1    Calloni, G.2    Chiti, F.3
  • 65
    • 0037168655 scopus 로고    scopus 로고
    • A structural model for Alzheimer's beta-amyloid fibrils based on experimental constraints from solid state NMR
    • Petkova A.T., Ishii Y., Balbach J.J., et al. A structural model for Alzheimer's beta-amyloid fibrils based on experimental constraints from solid state NMR. Proc Natl Acad Sci USA 99 26 (2002) 16742-16747
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.26 , pp. 16742-16747
    • Petkova, A.T.1    Ishii, Y.2    Balbach, J.J.3
  • 66
    • 12844260879 scopus 로고    scopus 로고
    • Association of thin filaments into thick filaments revealing the structural hierarchy of amyloid fibrils
    • Kanno T., Yamaguchi K., Naiki H., et al. Association of thin filaments into thick filaments revealing the structural hierarchy of amyloid fibrils. J Struct Biol 149 2 (2005) 213-218
    • (2005) J Struct Biol , vol.149 , Issue.2 , pp. 213-218
    • Kanno, T.1    Yamaguchi, K.2    Naiki, H.3
  • 67
    • 33144487701 scopus 로고    scopus 로고
    • Temporal profile of Abeta oligomerization in an in vivo model of Alzheimer's disease: a link between Abeta and tau pathology
    • Oddo S., Caccamo A., Tran L., et al. Temporal profile of Abeta oligomerization in an in vivo model of Alzheimer's disease: a link between Abeta and tau pathology. J Biol Chem 281 3 (2006) 1599-1604
    • (2006) J Biol Chem , vol.281 , Issue.3 , pp. 1599-1604
    • Oddo, S.1    Caccamo, A.2    Tran, L.3
  • 68
    • 0031459734 scopus 로고    scopus 로고
    • Molecular interactions between inhaled anesthetics and proteins
    • Eckenhoff R.G., and Johansson J.S. Molecular interactions between inhaled anesthetics and proteins. Pharmacol Rev 49 4 (1997) 343-367
    • (1997) Pharmacol Rev , vol.49 , Issue.4 , pp. 343-367
    • Eckenhoff, R.G.1    Johansson, J.S.2
  • 69
    • 0034730631 scopus 로고    scopus 로고
    • Inhaled anesthetic binding sites in human serum albumin
    • Eckenhoff R.G., Petersen C.E., Ha C.E., et al. Inhaled anesthetic binding sites in human serum albumin. J Biol Chem 275 39 (2000) 30439-30444
    • (2000) J Biol Chem , vol.275 , Issue.39 , pp. 30439-30444
    • Eckenhoff, R.G.1    Petersen, C.E.2    Ha, C.E.3
  • 70
    • 0032562141 scopus 로고    scopus 로고
    • Differential effects of general anesthetics on the quaternary structure of the Ca-ATPases of cardiac and skeletal sarcoplasmic reticulum
    • Kutchai H., Geddis L.M., Jones L.R., et al. Differential effects of general anesthetics on the quaternary structure of the Ca-ATPases of cardiac and skeletal sarcoplasmic reticulum. Biochemistry 37 8 (1998) 2410-2421
    • (1998) Biochemistry , vol.37 , Issue.8 , pp. 2410-2421
    • Kutchai, H.1    Geddis, L.M.2    Jones, L.R.3
  • 71
    • 0035845588 scopus 로고    scopus 로고
    • Anesthetic stabilization of protein intermediates: myoglobin and halothane
    • Eckenhoff R.G., Pidikiti R., and Reddy K.S. Anesthetic stabilization of protein intermediates: myoglobin and halothane. Biochemistry 40 36 (2001) 10819-10824
    • (2001) Biochemistry , vol.40 , Issue.36 , pp. 10819-10824
    • Eckenhoff, R.G.1    Pidikiti, R.2    Reddy, K.S.3
  • 72
    • 0028607523 scopus 로고
    • Cavities and packing at protein interfaces
    • Hubbard S.J., and Argos P. Cavities and packing at protein interfaces. Protein Sci 3 12 (1994) 2194-2206
    • (1994) Protein Sci , vol.3 , Issue.12 , pp. 2194-2206
    • Hubbard, S.J.1    Argos, P.2
  • 73
    • 27744505831 scopus 로고    scopus 로고
    • Structural stability of amyloid fibrils of beta(2)-microglobulin in comparison with its native fold
    • Chatani E., and Goto Y. Structural stability of amyloid fibrils of beta(2)-microglobulin in comparison with its native fold. Biochim Biophys Acta 1753 1 (2005) 64-75
    • (2005) Biochim Biophys Acta , vol.1753 , Issue.1 , pp. 64-75
    • Chatani, E.1    Goto, Y.2
  • 74
    • 4344594155 scopus 로고    scopus 로고
    • Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity
    • Eckenhoff R.G., Johansson J.S., Wei H., et al. Inhaled anesthetic enhancement of amyloid-beta oligomerization and cytotoxicity. Anesthesiology 101 3 (2004) 703-709
    • (2004) Anesthesiology , vol.101 , Issue.3 , pp. 703-709
    • Eckenhoff, R.G.1    Johansson, J.S.2    Wei, H.3
  • 75
    • 17644382712 scopus 로고    scopus 로고
    • Invertebrate models of Alzheimer's disease
    • Link C.D. Invertebrate models of Alzheimer's disease. Genes Brain Behav 4 3 (2005) 147-156
    • (2005) Genes Brain Behav , vol.4 , Issue.3 , pp. 147-156
    • Link, C.D.1
  • 76
    • 29444455075 scopus 로고    scopus 로고
    • Drosophila as a model for human neurodegenerative disease
    • Bilen J., and Bonini N.M. Drosophila as a model for human neurodegenerative disease. Annu Rev Genet 39 (2005) 153-171
    • (2005) Annu Rev Genet , vol.39 , pp. 153-171
    • Bilen, J.1    Bonini, N.M.2
  • 77
    • 0032727617 scopus 로고    scopus 로고
    • Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70
    • Warrick J.M., Chan H.Y., Chai Y., et al. Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat Genet 23 4 (1999) 425-428
    • (1999) Nat Genet , vol.23 , Issue.4 , pp. 425-428
    • Warrick, J.M.1    Chan, H.Y.2    Chai, Y.3
  • 78
    • 0028981288 scopus 로고
    • Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans
    • Link C.D. Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. Proc Natl Acad Sci USA 92 20 (1995) 9368-9372
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.20 , pp. 9368-9372
    • Link, C.D.1
  • 79
    • 0035109444 scopus 로고    scopus 로고
    • Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34
    • Link C.D., Johnson C.J., Fonte V., et al. Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34. Neurobiol Aging 22 2 (2001) 217-226
    • (2001) Neurobiol Aging , vol.22 , Issue.2 , pp. 217-226
    • Link, C.D.1    Johnson, C.J.2    Fonte, V.3
  • 80
    • 0037405291 scopus 로고    scopus 로고
    • Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model
    • Link C.D., Taft A., Kapulkin V., et al. Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model. Neurobiol Aging 24 3 (2003) 397-413
    • (2003) Neurobiol Aging , vol.24 , Issue.3 , pp. 397-413
    • Link, C.D.1    Taft, A.2    Kapulkin, V.3
  • 81
    • 2342473791 scopus 로고    scopus 로고
    • Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease
    • Iijima K., Liu H.P., Chiang A.S., et al. Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease. Proc Natl Acad Sci USA 101 17 (2004) 6623-6628
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.17 , pp. 6623-6628
    • Iijima, K.1    Liu, H.P.2    Chiang, A.S.3
  • 82
    • 2142645114 scopus 로고    scopus 로고
    • Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila
    • Greeve I., Kretzschmar D., Tschape J.A., et al. Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. J Neurosci 24 16 (2004) 3899-3906
    • (2004) J Neurosci , vol.24 , Issue.16 , pp. 3899-3906
    • Greeve, I.1    Kretzschmar, D.2    Tschape, J.A.3
  • 83
    • 0036468432 scopus 로고    scopus 로고
    • Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
    • Auluck P.K., Chan H.Y., Trojanowski J.Q., et al. Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295 5556 (2002) 865-868
    • (2002) Science , vol.295 , Issue.5556 , pp. 865-868
    • Auluck, P.K.1    Chan, H.Y.2    Trojanowski, J.Q.3
  • 84
    • 1542358895 scopus 로고    scopus 로고
    • PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
    • Nishimura I., Yang Y., and Lu B. PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila. Cell 116 5 (2004) 671-682
    • (2004) Cell , vol.116 , Issue.5 , pp. 671-682
    • Nishimura, I.1    Yang, Y.2    Lu, B.3
  • 85
    • 0037118247 scopus 로고    scopus 로고
    • Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
    • Jackson G.R., Wiedau-Pazos M., Sang T.K., et al. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 34 4 (2002) 509-519
    • (2002) Neuron , vol.34 , Issue.4 , pp. 509-519
    • Jackson, G.R.1    Wiedau-Pazos, M.2    Sang, T.K.3
  • 86
    • 17644370076 scopus 로고    scopus 로고
    • A case for a non-transgenic animal model of Alzheimer's disease
    • Stephan A., and Phillips A.G. A case for a non-transgenic animal model of Alzheimer's disease. Genes Brain Behav 4 3 (2005) 157-172
    • (2005) Genes Brain Behav , vol.4 , Issue.3 , pp. 157-172
    • Stephan, A.1    Phillips, A.G.2
  • 87
    • 17644370721 scopus 로고    scopus 로고
    • Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease
    • Kobayashi D.T., and Chen K.S. Behavioral phenotypes of amyloid-based genetically modified mouse models of Alzheimer's disease. Genes Brain Behav 4 3 (2005) 173-196
    • (2005) Genes Brain Behav , vol.4 , Issue.3 , pp. 173-196
    • Kobayashi, D.T.1    Chen, K.S.2
  • 88
    • 0028985574 scopus 로고
    • Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
    • Games D., Adams D., Alessandrini R., et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 373 6514 (1995) 523-527
    • (1995) Nature , vol.373 , Issue.6514 , pp. 523-527
    • Games, D.1    Adams, D.2    Alessandrini, R.3
  • 89
    • 0034700480 scopus 로고    scopus 로고
    • A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
    • Chen G., Chen K.S., Knox J., et al. A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease. Nature 408 6815 (2000) 975-979
    • (2000) Nature , vol.408 , Issue.6815 , pp. 975-979
    • Chen, G.1    Chen, K.S.2    Knox, J.3
  • 90
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • Hsiao K., Chapman P., Nilsen S., et al. Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274 5284 (1996) 99-102
    • (1996) Science , vol.274 , Issue.5284 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3
  • 91
    • 0036489445 scopus 로고    scopus 로고
    • The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease
    • Westerman M.A., Cooper-Blacketer D., Mariash A., et al. The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease. J Neurosci 22 5 (2002) 1858-1867
    • (2002) J Neurosci , vol.22 , Issue.5 , pp. 1858-1867
    • Westerman, M.A.1    Cooper-Blacketer, D.2    Mariash, A.3
  • 92
    • 0037266894 scopus 로고    scopus 로고
    • Age-dependent cognitive decline in the APP23 model precedes amyloid deposition
    • Van Dam D., D'Hooge R., Staufenbiel M., et al. Age-dependent cognitive decline in the APP23 model precedes amyloid deposition. Eur J Neurosci 17 2 (2003) 388-396
    • (2003) Eur J Neurosci , vol.17 , Issue.2 , pp. 388-396
    • Van Dam, D.1    D'Hooge, R.2    Staufenbiel, M.3
  • 93
    • 0011444914 scopus 로고    scopus 로고
    • Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
    • Sturchler-Pierrat C., Abramowski D., Duke M., et al. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc Natl Acad Sci USA 94 24 (1997) 13287-13292
    • (1997) Proc Natl Acad Sci USA , vol.94 , Issue.24 , pp. 13287-13292
    • Sturchler-Pierrat, C.1    Abramowski, D.2    Duke, M.3
  • 94
    • 0035282982 scopus 로고    scopus 로고
    • Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy
    • Winkler D.T., Bondolfi L., Herzig M.C., et al. Spontaneous hemorrhagic stroke in a mouse model of cerebral amyloid angiopathy. J Neurosci 21 5 (2001) 1619-1627
    • (2001) J Neurosci , vol.21 , Issue.5 , pp. 1619-1627
    • Winkler, D.T.1    Bondolfi, L.2    Herzig, M.C.3
  • 95
    • 0035877756 scopus 로고    scopus 로고
    • Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
    • Chishti M.A., Yang D.S., Janus C., et al. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 276 24 (2001) 21562-21570
    • (2001) J Biol Chem , vol.276 , Issue.24 , pp. 21562-21570
    • Chishti, M.A.1    Yang, D.S.2    Janus, C.3
  • 96
    • 0031914718 scopus 로고    scopus 로고
    • Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
    • Holcomb L., Gordon M.N., McGowan E., et al. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med 4 1 (1998) 97-100
    • (1998) Nat Med , vol.4 , Issue.1 , pp. 97-100
    • Holcomb, L.1    Gordon, M.N.2    McGowan, E.3
  • 97
    • 0035830686 scopus 로고    scopus 로고
    • Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
    • Arendash G.W., King D.L., Gordon M.N., et al. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res 891 1-2 (2001) 42-53
    • (2001) Brain Res , vol.891 , Issue.1-2 , pp. 42-53
    • Arendash, G.W.1    King, D.L.2    Gordon, M.N.3
  • 98
    • 0032886415 scopus 로고    scopus 로고
    • Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes
    • McGowan E., Sanders S., Iwatsubo T., et al. Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiol Dis 6 4 (1999) 231-244
    • (1999) Neurobiol Dis , vol.6 , Issue.4 , pp. 231-244
    • McGowan, E.1    Sanders, S.2    Iwatsubo, T.3
  • 99
    • 0034847176 scopus 로고    scopus 로고
    • Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes
    • Kurt M.A., Davies D.C., Kidd M., et al. Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes. Exp Neurol 171 1 (2001) 59-71
    • (2001) Exp Neurol , vol.171 , Issue.1 , pp. 59-71
    • Kurt, M.A.1    Davies, D.C.2    Kidd, M.3
  • 100
    • 3142668938 scopus 로고    scopus 로고
    • Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes
    • Howlett D.R., Richardson J.C., Austin A., et al. Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes. Brain Res 1017 1-2 (2004) 130-136
    • (2004) Brain Res , vol.1017 , Issue.1-2 , pp. 130-136
    • Howlett, D.R.1    Richardson, J.C.2    Austin, A.3
  • 101
    • 0346055155 scopus 로고    scopus 로고
    • BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease
    • Ohno M., Sametsky E.A., Younkin L.H., et al. BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease. Neuron 41 1 (2004) 27-33
    • (2004) Neuron , vol.41 , Issue.1 , pp. 27-33
    • Ohno, M.1    Sametsky, E.A.2    Younkin, L.H.3
  • 102
    • 0034426011 scopus 로고    scopus 로고
    • Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. [Erratum appears in Nat Genet 2000;26(1):127]
    • Lewis J., McGowan E., Rockwood J., et al. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. [Erratum appears in Nat Genet 2000;26(1):127]. Nat Genet 25 4 (2000) 401-405
    • (2000) Nat Genet , vol.25 , Issue.4 , pp. 401-405
    • Lewis, J.1    McGowan, E.2    Rockwood, J.3
  • 103
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
    • Oddo S., Caccamo A., Shepherd J.D., et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 39 3 (2003) 409-421
    • (2003) Neuron , vol.39 , Issue.3 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.D.3
  • 104
    • 14644442872 scopus 로고    scopus 로고
    • Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
    • Billings L.M., Oddo S., Green K.N., et al. Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice. Neuron 45 5 (2005) 675-688
    • (2005) Neuron , vol.45 , Issue.5 , pp. 675-688
    • Billings, L.M.1    Oddo, S.2    Green, K.N.3
  • 105
    • 6444222169 scopus 로고    scopus 로고
    • Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats
    • Culley D.J., Baxter M.G., Crosby C.A., et al. Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats. Anesth Analg 99 5 (2004) 1393-1397
    • (2004) Anesth Analg , vol.99 , Issue.5 , pp. 1393-1397
    • Culley, D.J.1    Baxter, M.G.2    Crosby, C.A.3
  • 106
    • 0037321378 scopus 로고    scopus 로고
    • Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits
    • Jevtovic-Todorovic V., Hartman R.E., Izumi Y., et al. Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci 23 3 (2003) 876-882
    • (2003) J Neurosci , vol.23 , Issue.3 , pp. 876-882
    • Jevtovic-Todorovic, V.1    Hartman, R.E.2    Izumi, Y.3
  • 107
    • 13844277020 scopus 로고    scopus 로고
    • The anesthetics nitrous oxide and ketamine are more neurotoxic to old than to young rat brain
    • Jevtovic-Todorovic V., and Carter L.B. The anesthetics nitrous oxide and ketamine are more neurotoxic to old than to young rat brain. Neurobiol Aging 26 6 (2005) 947-956
    • (2005) Neurobiol Aging , vol.26 , Issue.6 , pp. 947-956
    • Jevtovic-Todorovic, V.1    Carter, L.B.2
  • 108
    • 0028057861 scopus 로고
    • Alzheimer's disease and cumulative exposure to anesthesia: a case-control study
    • Bohnen N., Warner M.A., Kokmen E., et al. Alzheimer's disease and cumulative exposure to anesthesia: a case-control study. J Am Geriatr Soc 42 2 (1994) 198-201
    • (1994) J Am Geriatr Soc , vol.42 , Issue.2 , pp. 198-201
    • Bohnen, N.1    Warner, M.A.2    Kokmen, E.3
  • 109
    • 0028835612 scopus 로고
    • Parkinsonian symptoms during emergence from general anesthesia
    • Muravchick S., and Smith D.S. Parkinsonian symptoms during emergence from general anesthesia. Anesthesiology 82 1 (1995) 305-307
    • (1995) Anesthesiology , vol.82 , Issue.1 , pp. 305-307
    • Muravchick, S.1    Smith, D.S.2
  • 110
    • 0028483238 scopus 로고
    • Early and midlife exposure to anesthesia and age of onset of Alzheimer's disease
    • Bohnen N., Warner M.A., Kokmen E., et al. Early and midlife exposure to anesthesia and age of onset of Alzheimer's disease. Intern J Neurosci 77 3-4 (1994) 181-185
    • (1994) Intern J Neurosci , vol.77 , Issue.3-4 , pp. 181-185
    • Bohnen, N.1    Warner, M.A.2    Kokmen, E.3
  • 111
    • 0036271978 scopus 로고    scopus 로고
    • A case-control study on Alzheimer's disease and exposure to anesthesia
    • Gasparini M., Vanacore N., Schiaffini C., et al. A case-control study on Alzheimer's disease and exposure to anesthesia. Neurol Sci 23 1 (2002) 11-14
    • (2002) Neurol Sci , vol.23 , Issue.1 , pp. 11-14
    • Gasparini, M.1    Vanacore, N.2    Schiaffini, C.3
  • 112
    • 23944484938 scopus 로고    scopus 로고
    • Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty
    • Lee T.A., Wolozin B., Weiss K.B., et al. Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty. J Alzheimers Dis 7 4 (2005) 319-324
    • (2005) J Alzheimers Dis , vol.7 , Issue.4 , pp. 319-324
    • Lee, T.A.1    Wolozin, B.2    Weiss, K.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.