Age-dependent cognitive decline in the APP23 model precedes amyloid deposition

European Journal of Neuroscience

Volumn 17, Issue 2, 2003, Pages 388-396

  Van Dam, Debby ^a   D'Hooge, Rudi ^a,b   Staufenbiel, Matthias ^c   Van Ginneken, Chris ^d   Van Meir, Frans ^d   De Deyn, Peter P ^a,b  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b MIDDELHEIM HOSPITAL   (Belgium)

^c NOVARTIS PHARMA AG   (Switzerland)

^d UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Alzheimer's disease; Amyloid ; Memory deficit; Morris water maze; Transgenic mouse model

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

AGING; ALZHEIMER DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; COGNITIVE DEFECT; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; GENE MUTATION; HETEROZYGOSITY; HIPPOCAMPUS; HISTOPATHOLOGY; HYPERACTIVITY; LEARNING DISORDER; MALE; MAZE TEST; MEMORY DISORDER; MOTONEURON; NEOCORTEX; NONHUMAN; OPEN FIELD BEHAVIOR; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPATIAL MEMORY; TASK PERFORMANCE; TRANSGENIC MOUSE;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CHRONOBIOLOGY DISORDERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOHISTOCHEMISTRY; LEARNING; MEMORY; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; MOTOR ACTIVITY; MUTATION; SENILE PLAQUES;

EID: 0037266894     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02444.x     Document Type: Article

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