Prefibrillar amyloid protein aggregates share common features of cytotoxicity

Journal of Biological Chemistry

Volumn 279, Issue 30, 2004, Pages 31374-31382

  Bucciantini, Monica ^a   Calloni, Giulia ^a   Chiti, Fabrizio ^a   Formigli, Lucia ^a   Nosi, Daniele ^a   Dobson, Christopher M ^b,c   Stefani, Massimo ^a,c  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c Dept of Chemistry ^*  (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELLS; DISEASES; PATHOLOGY; POLYPEPTIDES; TOXICITY;

CELL DEATH; FIBROBLASTS; PROTEIN AGGREGATES; REACTIVE OXYGEN SPECIES;

PROTEINS;

AMYLOID PROTEIN; BACTERIAL PROTEIN; CALCIUM ION; FLUORESCENT DYE; HYPF PROTEIN; POLYPEPTIDE; REACTIVE OXYGEN METABOLITE; REDUCING AGENT; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; AMYLOIDOSIS; ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; CYTOTOXICITY; EMBRYO; FIBROBLAST; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; STRESS;

AMYLOID; ANIMALS; BACTERIAL PROTEINS; CALCIUM; CELL DEATH; MACROMOLECULAR SUBSTANCES; MICE; MICROSCOPY, CONFOCAL; NIH 3T3 CELLS; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; REACTIVE OXYGEN SPECIES;

ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE;

EID: 3843148352     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400348200     Document Type: Article

References (58)

1. Thomas, T., Thomas, G., McLendon, C., Sutton, T., and Mullan, M. (1996) Nature 380, 168-171
2. Pepys, M. B. (1995) in Oxford Textbook of Medicine (Wheaterall, D. J., Ledingham, J. G., and Warrel, D. A., eds) 3rd Ed., pp 1512-1524, Oxford University Press, Oxford
3. Koo, E. H., Lansbury, P. T., and Kelly, J. K. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9989-9990
4. Kelly, J. (1998) Curr. Opin. Struct. Biol. 8, 101-106
5. Selkoe, D. J. (2001) Physiol. Rev. 81, 741-766
6. Stefani, M., and Dobson, C. M. (2003) J. Mol. Med. 81, 678-699
7. Chiti, F., Webster, P., Taddei, N., Clark, A., Stefani, M., Ramponi, G., and Dobson, C. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3590-3594
8. Dobson, C. M. (2001) Philos. Trans. R. Soc. Lond. B Biol. Sci. 356, 133-145
9. Dobson, C. M. (2002) Nature 418, 729-730
10. Gujiarro, J. I. Sunde, M., Jones, J. A., Campbell, I. D., and Dobson, C. M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4224-4228
11. Chiti, F., Bucciantini, M., Capanni, C., Taddei, N., Dobson, C. M., and Stefani, M. (2001) Protein Sci. 10, 2541-2547
12. Bucciantini, M., Giannoni, E., Chiti, F., Baroni, F., Formigli, L., Zurdo, J., Taddei, N., Ramponi, G., Dobson, C. M., and Stefani, M. (2002) Nature 416, 507-511
13. Conway, K. A., Lee, S.-J., Rochet, J. C., Ding, T. T., Williamson, R. E., and Lansbury, P. T. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 571-576
14. Bhatia, R., Lin, H., and Lal, R. (2000) FASEB J. 14, 1233-1243
15. Goldberg, M. S., and Lansbury, P. T. (2000) Nat. Cell Biol. 2, E115-E119
16. Sousa, M. M., Cardoso, I., Fernandes, R., Guimaraes, A., and Saraiva, M. J. (2001) Am. J. Pathol. 159, 1993-2000
17. Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Nature 416, 535-539
18. Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Science 300, 486-489
19. Svanborg, C., Agerstam, H., Aronson, A., Bjerkvig, R., Duringer, C., Fischer, W., Gustafsson, L., Hallgren, O., Leijonhuvud, I., Linse, S., Mossberg, A.-K., Nilsson, H., Pettersson, J., and Svensson, M. (2003) Adv. Cancer Res. 88, 1-29
20. Abe, K., and Kimura, H. (1996) J. Neurochem. 67, 2074-2078
21. Grynkiewicz, G., Poenie, M., and Tsien, R. Y. (1985) J. Biol. Chem. 260, 3440-3450
22. Relini, A., Canale, C., Torrassa, S., Rolandi, R., Ghiozzi, A., Rosano, C., Bolognesi, M., Plakoutsi, G., Bucciantini, M., Chiti, F., and Stefani, M. (2004) J. Mol. Biol. 338, 943-957
23. Hirakura, Y., and Kagan, B. L. (2001) Amyloid 8, 94-100
24. Lin, H., Bhatia, R., and Lal, R. (2001) FASEB J. 15, 2433-2444
25. Lashuel, H.A., Hartley, D., Petre, B.M., Walz, T., and Lansbury, P.T. (2002) Nature 418, 291
26. Wang, L., Lashuel, H. A., Walz, T., and Colòn, W. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 15947-15952
27. Kranenburg, O., Kroon-Batenburg, L. M. J., Reijerkerk, A., Wu, Y.-P., Voest, E. E., and Gebbink, M. F. B. G. (2003) FEBS Lett. 539, 149-155
28. Yang, W., Dunlap, J. R., Andrews, R. B., and Wetzel, R. (2002) Hum. Mol. Genet. 11, 2905-2917
29. Morgan, B. P. (1999) Crit. Rev. Immunol. 19, 173-198
30. Tweten, R. K., Parker, M. W., and Johnson, A. E. (2001) in Pore Forming Toxins (van der Goot, G., ed) pp. 15-23, Springer-Verlag, Heidelberg.
31. Orrenius, S., Zhovotovsky, B., and Nicotera, P. (2003) Nat. Nat. Rev. 4, 552-565
32. Mattson, M. P. (1999) Methods Enzymol. 309, 733-768
33. Kruman, I. I., Pedersen, W. A., Springer, J. E., and Mattson, M. P. (1999) Exp. Neurol. 160, 28-39
34. Kawahara, M., Kuroda, Y., Arispe, N., and Rojas, E. (2000) J. Biol. Chem. 275, 14077-14083
35. Kanski, J., Varadarajan, S., Aksenova, M., and Butterfield, D. A. (2001) Biochim. Biophys. Acta 1586, 190-198
36. Milhavet, O., and Lehmann, S. (2002) Brain Res. Rev. 38, 328-339
37. Junn, E., and Mouradian, M.M. (2002) Neurosci. Lett. 320, 146-150
38. Wyttenbach, A., Sauvageot, O., Carmichael, J., Diaz-Latoud, C., Arrigo, A.-P., and Rubinsztein, D. C. (2002) Hum. Mol. Genet. 11, 1137-1151
39. Squier, T. C. (2001) Exp. Gerontol. 36, 1539-1550
40. Mattson, M. P., and Liu, D. (2002) Neuromol. Med. 2, 215-231
41. Tabner, B. J., Turnbull, S., El-Agnaf, O. M. A., and Allsop, D. (2002) Free Radic. Biol. Med. 32, 1076-1083
42. Andersson, K., Olofsson, A., Nielsen, E. H., Svehag, S. E., and Lundgreen, E. (2002) Biochem. Biophys. Res. Commun. 294, 309-314
43. Volles, M. J., and Lansbury, P. T. (2002) Biochemistry 41, 4595-4602
44. Kourie, J.I., and Henry, C.L. (2002) Clin. Exp. Pharmacol. Physiol. 29, 741-753
45. Hyun, D.-H., Lee, M., Hattori, N., Kubo, S.-I., Mizuno, Y., Halliwell, B., and Jenner, P. (2002) J. Biol. Chem. 277, 28572-28577
46. Keller, J. N., Huang, F. F., and Markesbery, W. R. (2002) Neuroscience 98, 149-156
47. Yamamoto, A., Lucas, J. J., and Hen, R. (2000) Cell 101, 57-66
48. Gillmore, J. D., Hawkins, P. N., and Pepys, M. B. (1997) British J. Haematol. 99, 245-256
49. Gillmore, J. D., Lovat, L. B., Persey, M. R., Pepys, M. B., and Hawkins P.N. (2001) Lancet 358, 24-29
50. Keller, J. N., Hanni, K. B., and Markesbery, W. R. (2000) J. Neurochem. 75, 436-439
51. McNaught, K. S., and Jenner, P. (2001) Neurosci. Lett. 297, 191-194
52. Waelter, S., Boeddrich, A., Lurz, R., Scherzinger, E., Lueder, G., Lehrach, H., and Wanker, E. E. (2001) Mol. Biol. Cell 12, 1393-1407
53. Pacifici, M., and Iozzo, R. V. (1988) J. Biol. Chem. 263, 2483-2492
54. Velez-Pardo, C., Arroyave, S. T., Lopera, F., Castano, A. D., and Jimenez Del Rio, M. (2001) J. Alzheimer's Dis. 3, 409-415
55. Turmaine, M., Raza, A. Mahal, A. Mangiarini, L., Bates, G. P., and Davies. S. W. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 8093-8097
56. Lane, N. J., Balbo, A., Fukuyama, R., Rapoport, S. I., and Galdzick, Z. (1998) J. Neurocytol. 27, 707-718
57. Watt, J. A., Pike, C. J., Walencewicz-Wasserman, A. J., and Cotman, C. W. (1994) Brain Res. 661, 147-156
58. Schwab, B. L., Guerini, D., Didszun, C., Bano, D., Ferrando-May, E., Fava, E., Tam, J., Xu, D., Xanthoudakis, S., Nicholson, D. W., Carafoli, E., and Nicotera, P. (2002) Cell Death Differ. 9, 818-831