-
1
-
-
0025103561
-
Transection of the rat olfactory nerve increases glial fibrillary acidic protein immunoreactivity from the olfactory bulb to the piriform cortex
-
Anders J. J., Johnson J. A. Transection of the rat olfactory nerve increases glial fibrillary acidic protein immunoreactivity from the olfactory bulb to the piriform cortex. Glia. 3:1990;17-25.
-
(1990)
Glia
, vol.3
, pp. 17-25
-
-
Anders, J.J.1
Johnson, J.A.2
-
2
-
-
0022457866
-
Short- And long-term consequences of intracranial injections of the excitotoxin, quinolinic acid, as evidenced by GFA immunohistochemistry of astrocytes
-
Bjorklund H., Olson L., Dahl D., Schwarcz R. Short- and long-term consequences of intracranial injections of the excitotoxin, quinolinic acid, as evidenced by GFA immunohistochemistry of astrocytes. Brain Res. 371:1986;267-277.
-
(1986)
Brain Res.
, vol.371
, pp. 267-277
-
-
Bjorklund, H.1
Olson, L.2
Dahl, D.3
Schwarcz, R.4
-
3
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
-
Borchelt D. R., Thinakaran G., Eckman C. B., Lee M. K., Davenport F., Ratovitsky T., Prada C. M., Kim G., Seekins S., Yager D., Slunt H. H., Wang R., Seeger M., Levey A. I., Gandy S. E., Copeland N. G., Jenkins N. A., Price D. L., Younkin S. G., Sisodia S. S. Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron. 5:1996;1005-1013.
-
(1996)
Neuron
, vol.5
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
4
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D. R., Ratovitski T., van Lare J., Lee M. L., Gonzales V., Jenkins N. A., Copeland N. G., Price D. L., Sisodia S. S. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 19:1997;939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.L.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
5
-
-
0027526419
-
Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
-
Cai X. D., Golde T. E., Younkin S. G. Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science. 259:1993;514-516.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.D.1
Golde, T.E.2
Younkin, S.G.3
-
6
-
-
0026745610
-
Mutation of the β amyloid precursor protein in familial Alzheimer's disease increases β protein production
-
Citron M., Oltersdorf T., Haass C., McConlogue L., Hung A. Y., Seubert P., Vigo-Pelfrey C., Lieberburg I., Selkoe D. J. Mutation of the β amyloid precursor protein in familial Alzheimer's disease increases β protein production. Nature. 360:1992;672-674.
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
7
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
Citron M., Westaway D., Xia W., Carlson G., Diehl T., Levesque G., Johnson-Wood K., Lee M., Seubert P., Davis A., Kholodenko D., Motter R., Sherrington R., Perry B., Yao H., Strome R., Lieberburg I., Rommens J., Kim S., Schenk D., Fraser P., St George Hyslop P., Selkoe D. J. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice. Nature Med. 3:1997;67-72.
-
(1997)
Nature Med.
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St George Hyslop, P.22
Selkoe, D.J.23
more..
-
8
-
-
16044366039
-
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
-
Duff K., Eckman C., Zehr C., Yu X., Prada C.-M., Perez-tur J., Hutton M., Buee L., Harigaya Y., Yager D., Morgan D., Gordon M. N., Holcomb L., Refolo L., Zenk B., Hardy J., Younkin S. Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1. Nature. 383:1996;710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
9
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F b-amyloid precursor protein
-
Games D., Adams D., Alessandrini R., Barbour R., Berthelette P., Blackwell C., Carr T., Clemena J., Donaldson T., Gillespie F., Guido T., Hagopian S., Johnson-Wood K., Khan K., Lee M., Leibowitz P., Leiberberg I., Little S., Masilah E., McConlogue L., Montoya-Zavala M., Mucke L., Paganini L., Penniman E., Power M., Schenk D., Seubert P., Snyder B., Soriano F., Tan H., Vitale J., Wadsworth S., Wolozin B., Zhao J. Alzheimer-type neuropathology in transgenic mice overexpressing V717F b-amyloid precursor protein. Nature. 373:1995;523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Berthelette, P.5
Blackwell, C.6
Carr, T.7
Clemena, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Leiberberg, I.17
Little, S.18
Masilah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
Seubert, P.27
Snyder, B.28
Soriano, F.29
Tan, H.30
Vitale, J.31
Wadsworth, S.32
Wolozin, B.33
Zhao, J.34
more..
-
10
-
-
0028179341
-
Chemical characterization of the Aβ17-42 peptide, a component of diffuse amyloid deposits of Alzheimer's disease
-
Gowing E., Roher A. E., Woods A. S., Cotter R. J., Chaney M., Little S. P., Ball M. J. Chemical characterization of the Aβ17-42 peptide, a component of diffuse amyloid deposits of Alzheimer's disease. J. Biol. Chem. 269:1994;10987-10990.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 10987-10990
-
-
Gowing, E.1
Roher, A.E.2
Woods, A.S.3
Cotter, R.J.4
Chaney, M.5
Little, S.P.6
Ball, M.J.7
-
11
-
-
0344936307
-
Ultrastructural localization of amyloid beta protein in transfected embryonal carcinoma (P19) cells after neuroectodermal differentiation
-
Grant S. M., Szyf M., Cuello A. C. Ultrastructural localization of amyloid beta protein in transfected embryonal carcinoma (P19) cells after neuroectodermal differentiation. Soc. Neurosci. 23:1997;540.
-
(1997)
Soc. Neurosci.
, vol.23
, pp. 540
-
-
Grant, S.M.1
Szyf, M.2
Cuello, A.C.3
-
12
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L., Gordon M. N., McGowan E., Yu X., Benkovic S., Jantzen P., Wright K., Saad I., Mueller R., Morgan D., Sanders S., Zehr C., O'Campo K., Hardy J., Prada C.-M., Eckman C., Younkin S., Hsiao K., Duff K. Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nature Med. 4:1998;97-100.
-
(1998)
Nature Med.
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.-M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
13
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao K., Chapman P., Nilsen S., Eckman C., Harigaya Y., Younkin S., Yang F., Cole G. Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science. 274:1996;99-102.
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
14
-
-
0029849644
-
Full-length amyloid-β(1-42(43) and amino-terminally modified and truncated amyloid-β42(43) deposit in diffuse plaques
-
Iwatsubo T., Saido T. C., Mann D. M. A., Lee V. M.-Y., Trojanowski J. Q. Full-length amyloid-β(1-42(43) and amino-terminally modified and truncated amyloid-β42(43) deposit in diffuse plaques. Am. J. Pathol. 149:1996;1823-1830.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 1823-1830
-
-
Iwatsubo, T.1
Saido, T.C.2
Mann, D.M.A.3
Lee, V.M.-Y.4
Trojanowski, J.Q.5
-
15
-
-
0027258525
-
The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
Jarrett J. T., Berger E. P., Lansbury P. T. Jr. The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease. Biochemistry. 32:1993;4693-4697.
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury P.T., Jr.3
-
16
-
-
9444276544
-
Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: Predominance of Abeta 42(43)
-
Mann D. M., Iwatsubo T., Cairns N. J., Lantos P. L., Nochlin D., Sumi S. M., Bird T. D., Poorkaj P., Hardy J., Hutton M., Prihar G., Crook R., Rossor M. N., Haltia M. Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: Predominance of Abeta 42(43). Ann. Neurol. 40:1996;149-156.
-
(1996)
Ann. Neurol.
, vol.40
, pp. 149-156
-
-
Mann, D.M.1
Iwatsubo, T.2
Cairns, N.J.3
Lantos, P.L.4
Nochlin, D.5
Sumi, S.M.6
Bird, T.D.7
Poorkaj, P.8
Hardy, J.9
Hutton, M.10
Prihar, G.11
Crook, R.12
Rossor, M.N.13
Haltia, M.14
-
17
-
-
0028855851
-
Dominant and differential deposition of distinct beta-amyloid peptide species, A-beta N3(pE), in senile plaques
-
Saido T. C., Iwatsubo T., Mann D. M. A., Shimada H., Ihara Y., Kawashima S. Dominant and differential deposition of distinct beta-amyloid peptide species, A-beta N3(pE), in senile plaques. Neuron. 14:1995;457-466.
-
(1995)
Neuron
, vol.14
, pp. 457-466
-
-
Saido, T.C.1
Iwatsubo, T.2
Mann, D.M.A.3
Shimada, H.4
Ihara, Y.5
Kawashima, S.6
-
18
-
-
0030582387
-
Amino- And carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain
-
Saido T. C., Yamao-Harigaya W., Iwatsubo T., Kawashima S. Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain. Neurosci. Lett. 215:1996;173-176.
-
(1996)
Neurosci. Lett.
, vol.215
, pp. 173-176
-
-
Saido, T.C.1
Yamao-Harigaya, W.2
Iwatsubo, T.3
Kawashima, S.4
-
19
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D., Eckman C., Jensen M., Song X., Citron M., Suzuki N., Bird T. D., Hardy J., Hutton M., Kukull W., Larson E., Levy-Lahad E., Viitanen M., Peskind E., Poorkaj P., Schellenberg G., Tanzi R., Wasco W., Lannfelt L., Selkoe D., Younkin S. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 2:1996;864-870.
-
(1996)
Nat. Med.
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
20
-
-
0026721943
-
Beta-amyloid precursor protein cleavage by a membrane-bound protease
-
Sisodia S. S. Beta-amyloid precursor protein cleavage by a membrane-bound protease. Proc. Natl. Acad. Sci. USA. 89:1992;6075-6079.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6075-6079
-
-
Sisodia, S.S.1
-
21
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology
-
Sturchler-Pierrat C., Abramoski D., Duke M., Wiederhold K.-H., Mistl C., Rothacher S., Ledermann B., Burki K., Frey P., Paganetti P. A., Waridel C., Calhoun M. E., Jucker M., Probst A., Staufenbiel M., Sommer B. Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. Proc. Natl. Acad. Sci. USA. 94:1997;13287-13292.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramoski, D.2
Duke, M.3
Wiederhold, K.-H.4
Mistl, C.5
Rothacher, S.6
Ledermann, B.7
Burki, K.8
Frey, P.9
Paganetti, P.A.10
Waridel, C.11
Calhoun, M.E.12
Jucker, M.13
Probst, A.14
Staufenbiel, M.15
Sommer, B.16
-
22
-
-
0029752755
-
The profile of soluble amyloid β protein in cultured cell media: Detection and quantification of amyloid β protein and variants by immunoprecipitation-mass spectrometry
-
Wang R., Sweeney D., Gandy S. E., Sisodia S. S. The profile of soluble amyloid β protein in cultured cell media: Detection and quantification of amyloid β protein and variants by immunoprecipitation-mass spectrometry. J. Biol. Chem. 271:1996;31894-31902.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31894-31902
-
-
Wang, R.1
Sweeney, D.2
Gandy, S.E.3
Sisodia, S.S.4
|