Transforming growth factor β1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression

Journal of Biological Chemistry

Volumn 281, Issue 34, 2006, Pages 24171-24181

  McMahon, Stephanie ^a   Charbonneau, Martine ^a   Grandmont, Sebastien ^a   Richard, Darren E ^b   Dubois, Claire M ^a,c  

^a UNIVERSITY OF SHERBROOKE   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c NONE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DNA; ENZYMES; GENES; GROWTH KINETICS; PATHOLOGY;

BINDING ACTIVITY; PROLYL HYDROXYLASE (PHD); TRANSFORMING GROWTH FACTOR; VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF);

CELLS;

FURIN; HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; SMAD ANCHOR FOR RECEPTOR ACTIVATION; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MICROENVIRONMENT; MOUSE; NONHUMAN; OXYGEN CONCENTRATION; PATHOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; TUMOR CELL;

EID: 33747691662     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604507200     Document Type: Article

References (87)

1. Kuwai, T., Kitadai, Y., Tanaka, S., Onogawa, S., Matsutani, N., Kaio, E., Ito, M., and Chayama, K. (2003) Int. J. Cancer 105, 176-181
2. Maxwell, P. H., Dachs, G. U., Gleadle, J. M., Nicholls, L. G., Harris, A. L., Stratford, I. J., Hankinson, O., Pugh, C. W., and Ratcliffe, P. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 8104-8109
3. Zhong, H., De Marzo, A. M., Laughner, E., Lim, M., Hilton, D. A., Zagzag, D., Buechler, P., Isaacs, W. B., Semenza, G. L., and Simons, J. W. (1999) Cancer Res. 59, 5830-5835
4. Kung, A. L., Wang, S., Klco, J. M., Kaelin, W. G., and Livingston, D. M. (2000) Nat. Med. 6, 1335-1340
5. Ravi, R., Mookerjee, B., Bhujwalla, Z. M., Sutter, C. H., Artemov, D., Zeng, Q., Dillehay, L. E., Madan, A., Semenza, G. L., and Bedi, A. (2000) Genes Dev. 14, 34-44
6. Stoeltzing, O., McCarty, M. F., Wey, J. S., Fan, F., Liu, W., Belcheva, A., Bucana, C. D., Semenza, G. L., and Ellis, L. M. (2004) J. Natl. Cancer Inst. 96, 946-956
7. Wang, G. L., Jiang, B. H., Rue, E. A., and Semenza, G. L. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 5510-5514
8. Ivan, M., Kondo, K., Yang, H., Kim, W., Valiando, J., Ohh, M., Salic, A., Asara, J. M., Lane, W. S., and Kaelin, W. G., Jr. (2001) Science 292, 464-468
9. Jaakkola, P., Mole, D. R., Tian, Y. M., Wilson, M. I., Gielbert, J., Gaskell, S. J., Kriegsheim, A., Hebestreit, H. F., Mukherji, M., Schofield, C. J., Maxwell, P. H., Pugh, C. W., and Ratcliffe, P. J. (2001) Science 292, 468-472
10. Maxwell, P. H., Wiesener, M. S., Chang, G. W., Clifford, S. C., Vaux, E. C., Cockman, M. E., Wykoff, C. C., Pugh, C. W., Maher, E. R., and Ratcliffe, P. J. (1999) Nature 399, 271-275
11. Epstein, A. C., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., Mukherji, M., Metzen, E., Wilson, M. I., Dhanda, A., Tian, Y. M., Masson, N., Hamilton, D. L., Jaakkola, P., Barstead, R., Hodgkin, J., Maxwell, P. H., Pugh, C. W., Schofield, C. J., and Ratcliffe, P. J. (2001) Cell 107, 43-54
12. Cioffi, C. L., Liu, X. Q., Kosinski, P. A., Garay, M., and Bowen, B. R. (2003) Biochem. Biophys. Res. Commun. 303, 947-953
13. Lieb, M. E., Menzies, K., Moschella, M. C., Ni, R., and Taubman, M. B. (2002) Biochem. Cell Biol. 80, 421-426
14. Berra, E., Benizri, E., Ginouves, A., Volmat, V., Roux, D., and Pouyssegur, J. (2003) EMBO J. 22, 4082-4090
15. Aprelikova, O., Chandramouli, G. V., Wood, M., Vasselli, J. R., Riss, J., Maranchie, J. K., Linehan, W. M., and Barrett, J. C. (2004) J. Cell. Biochem. 92, 491-501
16. Marxsen, J. H., Stengel, P., Doege, K., Heikkinen, P., Jokilehto, T., Wagner, T., Jelkmann, W., Jaakkola, P., and Metzen, E. (2004) Biochem. J. 381, 761-767
17. Metzen, E., Stiehl, D. P., Doege, K., Marxsen, J. H., Hellwig-Burgel, T., and Jelkmann, W. (2005) Biochem. J. 387, 711-717
18. Janssen, H. L., Haustermans, K. M., Sprong, D., Blommestijn, G., Hofland, I., Hoebers, F. J., Blijweert, E., Raleigh, J. A., Semenza, G. L., Varia, M. A., Balm, A. J., van Velthuysen, M. L., Delaere, P., Sciot, R., and Begg, A. C. (2002) Int. J. Radiat. Oncol. Biol. Phys. 54, 1537-1549
19. Vukovic, V., Haugland, H. K., Nicklee, T., Morrison, A. J., and Hedley, D. W. (2001) Cancer Res. 61, 7394-7398
20. Hellwig-Burgel, T., Rutkowski, K., Metzen, E., Fandrey, J., and Jelkmann, W. (1999) Blood 94, 1561-1567
21. Jung, Y. J., Isaacs, J. S., Lee, S., Trepel, J., and Neckers, L. (2003) FASEB J. 17, 2115-2117
22. Richard, D. E., Berra, E., and Pouyssegur, J. (2000) J. Biol. Chem. 275, 26765-26771
23. Fukuda, R., Hirota, K., Fan, F., Jung, Y. D., Ellis, L. M., and Semenza, G. L. (2002) J. Biol. Chem. 277, 38205-38211
24. Page, E. L., Robitaille, G. A., Pouyssegur, J., and Richard, D. E. (2002) J. Biol. Chem. 277, 48403-48409
25. Tacchini, L., De Ponti, C., Matteucci, E., Follis, R., and Desiderio, M. A. (2004) Carcinogenesis 25, 2089-2100
26. Treins, C., Giorgetti-Peraldi, S., Murdaca, J., Semenza, G. L., and Van Obberghen, E. (2002) J. Biol. Chem. 277, 27975-27981
27. Pasche, B. (2001) J. Cell. Physiol. 186, 153-168
28. Mantovani, A., Allavena, P., and Sica, A. (2004) Eur. J. Cancer 40, 1660-1667
29. Breier, G., Blum, S., Peli, J., Groot, M., Wild, C., Risau, W., and Reichmann, E. (2002) Int. J. Cancer 97, 142-148
30. Lu, S. L., Reh, D., Li, A. G., Woods, J., Corless, C. L., Kulesz-Martin, M., and Wang, X. J. (2004) Cancer Res. 64, 4405-4410
31. McMahon, S., Laprise, M. H., and Dubois, C. M. (2003) Exp. Cell Res. 291, 326-339
32. Santibanez, J. F., Guerrero, J., Quintanilla, M., Fabra, A., and Martinez, J. (2002) Biochem. Biophys. Res. Commun. 296, 267-273
33. Benckert, C., Jonas, S., Cramer, T., Von Marschall, Z., Schafer, G., Peters, M., Wagner, K., Radke, C., Wiedenmann, B., Neuhaus, P., Hocker, M., and Rosewicz, S. (2003) Cancer Res. 63, 1083-1092
34. Forsythe, J. A., Jiang, B. H., Iyer, N. V., Agani, F., Leung, S. W., Koos, R. D., and Semenza, G. L. (1996) Mol. Cell. Biol. 16, 4604-4613
35. Blanchette, F., Day, R., Dong, W., Laprise, M. H., and Dubois, C. M. (1997) J. Clin. Investig. 99, 1974-1983
36. McMahon, S., Grondin, F., McDonald, P. P., Richard, D. E., and Dubois, C. M. (2005) J. Biol. Chem. 280, 6561-6569
37. Gorlach, A., Diebold, I., Schini-Kerth, V. B., Berchner-Pfannschmidt, U., Roth, U., Brandes, R. P., Kietzmann, T., and Busse, R. (2001) Circ. Res. 89, 47-54
38. Shih, S. C., and Claffey, K. P. (2001) Growth Factors 19, 19-34
39. Blouin, C. C., Page, E. L., Soucy, G. M., and Richard, D. E. (2004) Blood 103, 1124-1130
40. Blanchette, F., Rivard, N., Rudd, P., Grondin, F., Attisano, L., and Dubois, C. M. (2001) J. Biol. Chem. 276, 33986-33994
41. Chomczynski, P. (1993) BioTechniques 15, 532-534; 536-537
42. Langlois, M. F., Zanger, K., Monden, T., Safer, J. D., Hollenberg, A. N., and Wondisford, F. E. (1997) J. Biol. Chem. 272, 24927-24933
43. Semenza, G. L., and Wang, G. L. (1992) Mol. Cell. Biol. 12, 5447-5454
44. Tian, H., McKnight, S. L., and Russell, D. W. (1997) Genes Dev. 11, 72-82
45. Wrana, J. L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X. F., and Massague, J. (1992) Cell 71, 1003-1014
46. Fukuchi, M., Miyazaki, T., Fukai, Y., Nakajima, M., Sohda, M., Masuda, N., Manda, R., Tsukada, K., Kato, H., and Kuwano, H. (2004) Clin. Cancer Res. 10, 2738-2741
47. Maehara, Y., Kakeji, Y., Kabashima, A., Emi, Y., Watanabe, A., Akazawa, K., Baba, H., Kohnoe, S., and Sugimachi, K. (1999) J. Clin. Oncol. 17, 607-614
48. Huang, L. E., Gu, J., Schau, M., and Bunn, H. F. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7987-7992
49. Salceda, S., and Caro, J. (1997) J. Biol. Chem. 272, 22642-22647
50. Salnikow, K., Donald, S. P., Bruick, R. K., Zhitkovich, A., Phang, J. M., and Kasprzak, K. S. (2004) J. Biol. Chem. 279, 40337-40344
51. Wang, G. L., and Semenza, G. L. (1993) Blood 82, 3610-3615
52. Jewell, U. R., Kvietikova, I., Scheid, A., Bauer, C., Wenger, R. H., and Gassmann, M. (2001) FASEB J. 15, 1312-1314
53. Masson, N., Willam, C., Maxwell, P. H., Pugh, C. W., and Ratcliffe, P. J. (2001) EMBO J. 20, 5197-5206
54. Treins, C., Giorgetti-Peraldi, S., Murdaca, J., Monthouel-Kartmann, M. N., and Van Obberghen, E. (2005) Mol. Endocrinol. 19, 1304-1317
55. Massague, J., and Wotton, D. (2000) EMBO J. 19, 1745-1754
56. Laping, N. J., Grygielko, E., Mathur, A., Butter, S., Bomberger, J., Tweed, C., Martin, W., Fornwald, J., Lehr, R., Harling, J., Gaster, L., Callahan, J. F., and Olson, B. A. (2002) Mol. Pharmacol. 62, 58-64
57. Dubois, C. M., Laprise, M. H., Blanchette, F., Gentry, L. E., and Leduc, R. (1995) J. Biol. Chem. 270, 10618-10624
58. Dubois, C. M., Blanchette, F., Laprise, M. H., Leduc, R., Grondin, F., and Seidah, N. G. (2001) Am. J. Pathol. 158, 305-316
59. Javelaud, D., Delmas, V., Moller, M., Sextius, P., Andre, J., Menashi, S., Larue, L., and Mauviel, A. (2005) Oncogene 24, 7624-7629
60. Kim, E. S., Kim, M. S., and Moon, A. (2004) Int. J. Oncol. 25, 1375-1382
61. Shimizu, S., Nishikawa, Y., Kuroda, K., Takagi, S., Kozaki, K., Hyuga, S., Saga, S., and Matsuyama, M. (1996) Cancer Res. 56, 3366-3370
62. Jean, F., Stella, K., Thomas, L., Liu, G., Xiang, Y., Reason, A. J., and Thomas, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 7293-7298
63. Laprise, M. H., Grondin, F., Cayer, P., McDonald, P. P., and Dubois, C. M. (2002) Blood 100, 3578-3587
64. Garten, W., Hallenberger, S., Ortmann, D., Schafer, W., Vey, M., Angliker, H., Shaw, E., and Klenk, H. D. (1994) Biochimie (Paris) 76, 217-225
65. Kourembanas, S., Morita, T., Liu, Y., and Christou, H. (1997) Kidney Int. 51, 438-443
66. Siegfried, G., Khatib, A. M., Benjannet, S., Chretien, M., and Seidah, N. G. (2003) Cancer Res. 63, 1458-1463
67. Chua, C. C., Hamdy, R. C., and Chua, B. H. (2000) Biochim. Biophys. Acta 1497, 69-76
68. Donovan, D., Harmey, J. H., Toomey, D., Osborne, D. H., Redmond, H. P., and Bouchier-Hayes, D. J. (1997) Ann. Surg. Oncol. 4, 621-627
69. Sugano, Y., Matsuzaki, K., Tahashi, Y., Furukawa, F., Mori, S., Yamagata, H., Yoshida, K., Matsushita, M., Nishizawa, M., Fujisawa, J., and Inoue, K. (2003) Oncogene 22, 2309-2321
70. Chun, Y. S., Yeo, E. J., Choi, E., Teng, C. M., Bae, J. M., Kim, M. S., and Park, J. W. (2001) Biochem. Pharmacol. 61, 947-954
71. Yeo, E. J., Chun, Y. S., Cho, Y. S., Kim, J., Lee, J. C., Kim, M. S., and Park, J. W. (2003) J. Natl. Cancer Inst. 95, 516-525
72. Zhou, J., Schmid, T., and Brune, B. (2003) Mol. Biol. Cell 14, 2216-2225
73. Hu, B., Tack, D. C., Liu, T., Wu, Z., Ullenbruch, M. R., and Phan, S. H. (2006) Oncogene 25, 1030-1041
74. Vogelmann, R., Nguyen-Tat, M. D., Giehl, K., Adler, G., Wedlich, D., and Menke, A. (2005) J. Cell Sci. 118, 4901-4912
75. Yagi, K., Furuhashi, M., Aoki, H., Goto, D., Kuwano, H., Sugamura, K., Miyazono, K., and Kato, M. (2002) J. Biol. Chem. 277, 854-861
76. Long, J., Zuo, D., and Park, M. (2005) J. Biol. Chem. 280, 35477-35489
77. Peinado, H., Marin, F., Cubillo, E., Stark, H. J., Fusenig, N., Nieto, M. A., and Cano, A. (2004) J. Cell Sci. 117, 2827-2839
78. Metzen, E., Zhou, J., Jelkmann, W., Fandrey, J., and Brune, B. (2003) Mol. Biol. Cell 14, 3470-3481
79. Chiu, C., Maddock, D. A., Zhang, Q., Souza, K. P., Townsend, A. R., and Wan, Y. (2001) Int. J. Mol. Med. 8, 251-255
80. Herrera, B., Murillo, M. M., Alvarez-Barrientos, A., Beltran, J., Fernandez, M., and Fabregat, I. (2004) Free Radic. Biol. Med. 36, 16-26
81. Blancher, C., Moore, J. W., Talks, K. L., Houlbrook, S., and Harris, A. L. (2000) Cancer Res. 60, 7106-7113
82. Vleugel, M. M., Greijer, A. E., Shvarts, A., van der Groep, P., van Berkel, M., Aarbodem, Y., van Tinteren, H., Harris, A. L., van Diest, P. J., and van der Wall, E. (2005) J. Clin. Pathol. 58, 172-177
83. Zhong, H., Agani, F., Baccala, A. A., Laughner, E., Rioseco-Camacho, N., Isaacs, W. B., Simons, J. W., and Semenza, G. L. (1998) Cancer Res. 58, 5280-5284
84. Mbikay, M., Sirois, F., Yao, J., Seidah, N. G., and Chretien, M. (1997) Br. J. Cancer 75, 1509-1514
85. Cheng, M., Watson, P. H., Paterson, J. A., Seidah, N., Chretien, M., and Shiu, R. P. (1997) Int. J. Cancer 71, 966-971
86. Coombes, R. C., Barrett-Lee, P., and Luqmani, Y. (1990) J. Steroid Biochem. Mol. Biol. 37, 833-836
87. Hasegawa, Y., Takanashi, S., Kanehira, Y., Tsushima, T., Imai, T., and Okumura, K. (2001) Cancer 91, 964-971