TGFβ-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN

Journal of Cell Science

Volumn 118, Issue 20, 2005, Pages 4901-4912

  Vogelmann, Roger ^a,c   Nguyen Tat, Marc Daniel ^a   Giehl, Klaudia ^a   Adler, Guido ^a   Wedlich, Doris ^b   Menke, Andre ^a  

^a UNIVERSITY OF ULM   (Germany)

^b UNIVERSITY OF KARLSRUHE   (Germany)

^c STANFORD UNIVERSITY   (United States)

Author keywords

catenin tyrosine phosphorylation; Cell migration; Cell cell adhesion; E cadherin; Epithelial cells; Invasion; Pancreatic cancer; Transforming growth factor beta

Indexed keywords

ACTIN; ALPHA CATENIN; BETA CATENIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAS PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CADHERIN; CATENIN; CHROMONE DERIVATIVE; FLAVONOID; MORPHOLINE DERIVATIVE; MULTIPROTEIN COMPLEX; PROTEIN P21; PTEN PROTEIN, HUMAN;

ARTICLE; CANCER CELL; CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CELL STRAIN; CONTROLLED STUDY; CYTOSKELETON; DISSOCIATION; DOWN REGULATION; EPITHELIUM CELL; GENE DELETION; HOMOZYGOSITY; HUMAN; HUMAN CELL; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; CELL AGGREGATION; CELL MOTION; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN BINDING; TUMOR CELL LINE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CADHERINS; CATENINS; CELL ADHESION; CELL AGGREGATION; CELL LINE, TUMOR; CELL MOVEMENT; CHROMONES; DOWN-REGULATION; FLAVONOIDS; HUMANS; MORPHOLINES; MULTIPROTEIN COMPLEXES; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS P21(RAS); PTEN PHOSPHOHYDROLASE; TRANSFORMING GROWTH FACTOR BETA;

EID: 27844478189     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02594     Document Type: Article

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