-
1
-
-
0031882260
-
Reactive oxygen species as mediators of signal transduction in cardiovascular disease
-
Abe J.-I., Berk B.C. Reactive oxygen species as mediators of signal transduction in cardiovascular disease. Trends Cardiovasc. Med. 8:1998;59-64.
-
(1998)
Trends Cardiovasc. Med.
, vol.8
, pp. 59-64
-
-
Abe, J.-I.1
Berk, B.C.2
-
2
-
-
0034053099
-
Pathophysiology of ischemia-reperfusion injury
-
Carden D.L., Granger D.N. Pathophysiology of ischemia-reperfusion injury. J. Pathol. 190:2000;255-266.
-
(2000)
J. Pathol.
, vol.190
, pp. 255-266
-
-
Carden, D.L.1
Granger, D.N.2
-
3
-
-
0030963616
-
The hypoxic response: Huffing and HIFing
-
Guillemin K., Krasnow M.A. The hypoxic response: Huffing and HIFing. Cell. 89:1997;9-12.
-
(1997)
Cell
, vol.89
, pp. 9-12
-
-
Guillemin, K.1
Krasnow, M.A.2
-
4
-
-
0033233243
-
2 homeostasis by hypoxia-inducible factor 1
-
2 homeostasis by hypoxia-inducible factor 1 Annu. Rev. Cell Dev. Biol. 15:1999;551-578.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
5
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
Bruick R.K., McKnight S.L. A conserved family of prolyl-4-hydroxylases that modify HIF. Science. 294:2001;1337-1340.
-
(2001)
Science
, vol.294
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
6
-
-
0035917808
-
2 -regulated prolyl hydroxylation
-
2 -regulated prolyl hydroxylation Science. 292:2001;468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Von Kreiegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, R.J.13
-
7
-
-
0035917313
-
2 sensing
-
2 sensing Science. 292:2001;464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin, W.S.10
-
8
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein A.C.R., Gleadle J.M., McNeill L.A., Hewitson K.S., O'Rourke J., Mole D.R., Mukherji M., Metzen E., Wilson M.I., Dhanda A., Tian Y.-M., Masson N., Hamilton D.L., Jaakkola P., Barstead R., Hodgkin J., Maxwell P.H., Pugh C.W., Schofield C.J., Ratcliffe P.J. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell. 107:2001;43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.-M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
9
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
-
Masson N., William C., Maxwell P.H., Pugh C.W., Ratcliffe P.J. Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation. EMBO J. 20:2001;5197-5206.
-
(2001)
EMBO J.
, vol.20
, pp. 5197-5206
-
-
Masson, N.1
William, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
10
-
-
0035859692
-
HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
-
Yu F., White S.B., Zhao Q., Lee F.S. HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation. Proc. Natl. Acad. Sci. USA. 98:2001;9630-9635.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9630-9635
-
-
Yu, F.1
White, S.B.2
Zhao, Q.3
Lee, F.S.4
-
11
-
-
0036374233
-
Regulation of the HIF pathway: Enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex
-
Mole D.R., Pugh C.W., Ratcliffe P.J., Maxwell P.H. Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex. Adv. Enzyme Regul. 42:2002;333-347.
-
(2002)
Adv. Enzyme Regul.
, vol.42
, pp. 333-347
-
-
Mole, D.R.1
Pugh, C.W.2
Ratcliffe, P.J.3
Maxwell, P.H.4
-
12
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
-
Lando D., Peet D.J., Whelan D.A., Gorman J.J., Whitelaw M.L. Asparagine hydroxylation of the HIF transactivation domain: a hypoxic switch. Science. 295:2002;858-861.
-
(2002)
Science
, vol.295
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
13
-
-
18544386401
-
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
-
Hewitson K.S., McNeill L.A., Riordan M.V., Tian Y.-M., Bullock A.N., Welford R.W., Elkins J.M., Oldham N.J., Bhattacharya S., Gleadle J.M., Radcliffe P.J., Pugh C.W., Schofield C.J. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. J. Biol. Chem. 277:2002;26351-26355.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26351-26355
-
-
Hewitson, K.S.1
McNeill, L.A.2
Riordan, M.V.3
Tian, Y.-M.4
Bullock, A.N.5
Welford, R.W.6
Elkins, J.M.7
Oldham, N.J.8
Bhattacharya, S.9
Gleadle, J.M.10
Radcliffe, P.J.11
Pugh, C.W.12
Schofield, C.J.13
-
14
-
-
0036320934
-
2 -regulated gene expression
-
2 -regulated gene expression FASEB J. 16:2002;1151-1162.
-
(2002)
FASEB J.
, vol.16
, pp. 1151-1162
-
-
Wenger, R.H.1
-
15
-
-
0036469146
-
Oxygen sensing gets a second wind
-
Bruick R.K., McKnight S.L. Oxygen sensing gets a second wind. Science. 295:2002;807-808.
-
(2002)
Science
, vol.295
, pp. 807-808
-
-
Bruick, R.K.1
McKnight, S.L.2
-
16
-
-
0036710591
-
Signal transduction to hypoxia-inducible factor 1
-
Semenza G.L. Signal transduction to hypoxia-inducible factor 1. Biochem. Pharmacol. 64:2002;993-998.
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 993-998
-
-
Semenza, G.L.1
-
17
-
-
0036037635
-
From erythropoietin to oxygen: Hypoxia-inducible factor hydroxylases and the hypoxia signal pathway
-
Ratcliffe P.J. From erythropoietin to oxygen: hypoxia-inducible factor hydroxylases and the hypoxia signal pathway. Blood Purif. 20:2002;445-450.
-
(2002)
Blood Purif.
, vol.20
, pp. 445-450
-
-
Ratcliffe, P.J.1
-
18
-
-
0037155247
-
Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene
-
Minchenko A., Leshchinsky I., Opentanova I., Sang N., Srinivas V., Armstead V., Caro J. Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. J. Biol. Chem. 277:2002;6183-6187.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6183-6187
-
-
Minchenko, A.1
Leshchinsky, I.2
Opentanova, I.3
Sang, N.4
Srinivas, V.5
Armstead, V.6
Caro, J.7
-
19
-
-
0037060621
-
Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1α
-
Jiang C., Lu H., Vincent K.A., Shankara S., Belanger A.J., Cheng S.H., Akita G.Y., Kelly R.A., Goldberg M.A., Gregory R.J. Gene expression profiles in human cardiac cells subjected to hypoxia or expressing a hybrid form of HIF-1α Physiol. Genom. 8:2002;23-32.
-
(2002)
Physiol. Genom.
, vol.8
, pp. 23-32
-
-
Jiang, C.1
Lu, H.2
Vincent, K.A.3
Shankara, S.4
Belanger, A.J.5
Cheng, S.H.6
Akita, G.Y.7
Kelly, R.A.8
Goldberg, M.A.9
Gregory, R.J.10
-
20
-
-
0034640269
-
Hypoxic induction of prolyl 4-hydroxylase α (I) in cultured cells
-
Takahashi Y., Takahashi S., Shiga Y., Yoshimi T., Miura T. Hypoxic induction of prolyl 4-hydroxylase α (I) in cultured cells. J. Biol. Chem. 275:2000;14139-14146.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14139-14146
-
-
Takahashi, Y.1
Takahashi, S.2
Shiga, Y.3
Yoshimi, T.4
Miura, T.5
-
21
-
-
0037064010
-
Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells
-
Fukuda R., Hirota K., Fan F., Jung Y.D., Ellis L.M., Semenza G.L. Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J. Biol. Chem. 277:2002;38205-38211.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 38205-38211
-
-
Fukuda, R.1
Hirota, K.2
Fan, F.3
Jung, Y.D.4
Ellis, L.M.5
Semenza, G.L.6
-
22
-
-
0035936886
-
HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1α degradation
-
Berra E., Richard D.E., Gothie E., Pouyssegur J. HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1α degradation. FEBS Lett. 491:2001;85-90.
-
(2001)
FEBS Lett.
, vol.491
, pp. 85-90
-
-
Berra, E.1
Richard, D.E.2
Gothie, E.3
Pouyssegur, J.4
-
23
-
-
0345504968
-
Prolyl 4-hydrolase inhibition induced HIF and improved cardiac function after myocardial infarction
-
Philipp S., Schiche A., Pilz B., Jurgensen J.-S., Eckart K.-U., Pagel I., Langenickel T., Gunzler V., Willenbrock R. Prolyl 4-hydrolase inhibition induced HIF and improved cardiac function after myocardial infarction. Circulation. 106:2002;II-267.
-
(2002)
Circulation
, vol.106
, pp. 267
-
-
Philipp, S.1
Schiche, A.2
Pilz, B.3
Jurgensen, J.-S.4
Eckart, K.-U.5
Pagel, I.6
Langenickel, T.7
Gunzler, V.8
Willenbrock, R.9
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