Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: Impact on the bioactivation of proproteins

Journal of Biological Chemistry

Volumn 280, Issue 8, 2005, Pages 6561-6569

  McMahon, Stephanie ^a   Grondin, Francine ^a   McDonald, Patrick P ^a   Richard, Darren E ^b   Dubois, Claire M ^a,c  

^a UNIVERSITY OF SHERBROOKE   (Canada)

^b LAVAL UNIVERSITY   (Canada)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELLS; ENZYMES; GENES; RNA; SUBSTRATES;

BIOACTIVATION; HYPOXIA-INDUCIBLE FACTOR-1 (HIF-1); TRANSFECTION; TUMORIGENESIS;

PROTEINS;

FURIN; HYPOXIA INDUCIBLE FACTOR 1; MESSENGER RNA; PROPROTEIN CONVERTASE 1; TRANSFORMING GROWTH FACTOR BETA1;

ANGIOGENESIS; ARTICLE; BINDING SITE; CANCER INVASION; CARCINOGENESIS; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN PROCESSING; REPORTER GENE;

EID: 14844299760     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413248200     Document Type: Article

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