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Volumn 15, Issue 11, 2005, Pages 1595-1616

Regulatory T cells for immunotherapy of autoimmune diseases: From the bench to the bedside

Author keywords

Granulocyte colony stimulating factor; IL 10; Regulatory T cell (Treg); Transforming growth factor

Indexed keywords

BASILIXIMAB; CD4 ANTIGEN; CHIMERIC ANTIBODY; FC RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; GRANZYME B; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; KM 2760; OKT 3; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 27944507804     PISSN: 13543776     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543776.15.11.1595     Document Type: Review
Times cited : (4)

References (169)
  • 1
    • 0035862336 scopus 로고    scopus 로고
    • Differentiation of T regulatory cells by immature dendritic cells
    • RONCAROLO MG, LEVINGS MK, TRAVERSARI C: Differentiation of T regulatory cells by immature dendritic cells. J. Exp. Med. (2001) 193:F5-F9.
    • (2001) J. Exp. Med. , vol.193
    • Roncarolo, M.G.1    Levings, M.K.2    Traversari, C.3
  • 2
    • 0037361819 scopus 로고    scopus 로고
    • Antigen-induced regulatory T cells in autoimmunity
    • VON HERRATH MG, HARRISON LC: Antigen-induced regulatory T cells in autoimmunity. Nat. Rev. Immunol. (2003) 3:223-232.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 223-232
    • Von Herrath, M.G.1    Harrison, L.C.2
  • 3
    • 0346996879 scopus 로고    scopus 로고
    • The regulatory T cell family: Distinct subsets and their interrelations
    • JONULEIT H, SCHMITT E: The regulatory T cell family: distinct subsets and their interrelations. J. Immunol. (2003) 171:6323-6327.
    • (2003) J. Immunol. , vol.171 , pp. 6323-6327
    • Jonuleit, H.1    Schmitt, E.2
  • 5
    • 0344984407 scopus 로고    scopus 로고
    • Dendritic cells: Regulators of alloimmunity and opportunities for tolerance induction
    • MORELLI AE, THOMSON AW: Dendritic cells: regulators of alloimmunity and opportunities for tolerance induction. Immunol. Rev. (2003) 196:125-146.
    • (2003) Immunol. Rev. , vol.196 , pp. 125-146
    • Morelli, A.E.1    Thomson, A.W.2
  • 6
    • 0035186416 scopus 로고    scopus 로고
    • H3 regulatory cells
    • H3 regulatory cells. Immunol. Rev. (2001) 182:207-214.
    • (2001) Immunol. Rev. , vol.182 , pp. 207-214
    • Weiner, H.L.1
  • 7
    • 17144374934 scopus 로고    scopus 로고
    • Regulatory T-cell therapy: Is it ready for the clinic?
    • BLUESTONE JA: Regulatory T-cell therapy: is it ready for the clinic? Nat. Rev. Immunol. (2005) 5:343-349.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 343-349
    • Bluestone, J.A.1
  • 8
    • 0030704726 scopus 로고    scopus 로고
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 389:737-742.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 9
    • 0028158319 scopus 로고
    • High levels of interleukin-10 production in vivo are associated with tolerance in SCID patients transplanted with HLA-mismatched hematopoietic stem cells
    • BACCHETTA R, BIGLER M, TOURAINE JL et al.: High levels of interleukin-10 production in vivo are associated with tolerance in SCID patients transplanted with HLA-mismatched hematopoietic stem cells. J. Exp. Med. (1994) 179:493-502.
    • (1994) J. Exp. Med. , vol.179 , pp. 493-502
    • Bacchetta, R.1    Bigler, M.2    Touraine, J.L.3
  • 12
    • 10744226541 scopus 로고    scopus 로고
    • Regulatory T cells and dendritic cells in transplantation tolerance: Molecular markers and mechanisms
    • COBBOLD SP, NOLAN KF, GRACA L et al.: Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms. Immunol. Rev. (2003) 196:109-124.
    • (2003) Immunol. Rev. , vol.196 , pp. 109-124
    • Cobbold, S.P.1    Nolan, K.F.2    Graca, L.3
  • 17
    • 3242677783 scopus 로고    scopus 로고
    • Regulatory T cells and tolerogenic dendritic cells: From basic biology to clinical applications
    • RUTELLA S, LEMOLI RM: Regulatory T cells and tolerogenic dendritic cells: from basic biology to clinical applications. Immunol. Lett. (2004) 94:11-26.
    • (2004) Immunol. Lett. , vol.94 , pp. 11-26
    • Rutella, S.1    Lemoli, R.M.2
  • 23
    • 0037131969 scopus 로고    scopus 로고
    • + T suppressor cell clones produce transforming growth factor β, but not interleukin 10, and are distinct from Type 1 T regulatory cells
    • + T suppressor cell clones produce transforming growth factor β, but not interleukin 10, and are distinct from Type 1 T regulatory cells. J. Exp. Med. (2002) 196:1335-1346.
    • (2002) J. Exp. Med. , vol.196 , pp. 1335-1346
    • Levings, M.K.1    Sangregorio, R.2    Sartirana, C.3
  • 25
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nat. Rev. Immunol. (2002) 2:389-400.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 27
    • 0346024088 scopus 로고    scopus 로고
    • + regulatory T cells in the absence of STAT1: Increased susceptibility to autoimmune disease
    • + regulatory T cells in the absence of STAT1: increased susceptibility to autoimmune disease. J. Exp. Med. (2004) 199:25-34.
    • (2004) J. Exp. Med. , vol.199 , pp. 25-34
    • Nishibori, T.1    Tanabe, Y.2    Su, L.3    David, M.4
  • 30
    • 0242493801 scopus 로고    scopus 로고
    • Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells
    • YVON ES, VIGOUROUX S, ROUSSEAU RF et al.: Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells. Blood. (2003) 102:3815-3821.
    • (2003) Blood , vol.102 , pp. 3815-3821
    • Yvon, E.S.1    Vigouroux, S.2    Rousseau, R.F.3
  • 32
    • 0142250482 scopus 로고    scopus 로고
    • Regulatory T cells under scrutiny
    • BACH JF: Regulatory T cells under scrutiny. Nat. Rev. Immunol. (2003) 3:189-198.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 189-198
    • Bach, J.F.1
  • 34
  • 37
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • BRUNKOW ME, JEFFERY EW, HJERRILD KA et al.: Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. (2001) 27:68-73.
    • (2001) Nat. Genet. , vol.27 , pp. 68-73
    • Brunkow, M.E.1    Jeffery, E.W.2    Hjerrild, K.A.3
  • 38
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development of the transcription factor FoxP3
    • HORI S, NOMURA T, SAKAGUCHI S: Control of regulatory T cell development of the transcription factor FoxP3. Science. (2003) 299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 39
    • 0348223787 scopus 로고    scopus 로고
    • + regulatory T cells by TGF-β induction of transcription factor FoxP3
    • + regulatory T cells by TGF-β induction of transcription factor FoxP3. J. Exp. Med. (2003) 198:1875-1886.
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3
  • 44
    • 20844449950 scopus 로고    scopus 로고
    • New tools to identify regulatory T cells
    • GRACA L: New tools to identify regulatory T cells. Eur. J. Immunol. (2005) 35:1678-1680.
    • (2005) Eur. J. Immunol. , vol.35 , pp. 1678-1680
    • Graca, L.1
  • 47
    • 0034077559 scopus 로고    scopus 로고
    • + regulatory T cells downregulate costimulatory molecules on antigen-presenting cells
    • + regulatory T cells downregulate costimulatory molecules on antigen-presenting cells. Eur. J. Immunol. (2000) 30:1538-1543.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1538-1543
    • Cederbom, L.1    Hall, H.2    Ivans, F.3
  • 49
    • 0037099733 scopus 로고    scopus 로고
    • + regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent Type 1-like regulatory T cells
    • + regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent Type 1-like regulatory T cells. J. Exp. Med. (2002) 196:247-253.
    • (2002) J. Exp. Med. , vol.196 , pp. 247-253
    • Dieckmann, D.1    Bruett, C.H.2    Ploettner, H.3    Lutz, M.B.4    Schuler, G.5
  • 50
    • 0035801335 scopus 로고    scopus 로고
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor β
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor β. J. Exp. Med. (2001) 194:629-644.
    • (2001) J. Exp. Med. , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 52
    • 0346119234 scopus 로고    scopus 로고
    • Modulation of tryptophan catabolism by regulatory T cells
    • FALLARINO F, GROHMANN U, HWANG KW et al.: Modulation of tryptophan catabolism by regulatory T cells. Nat. Immunol. (2003) 4:1206-1212.
    • (2003) Nat. Immunol. , vol.4 , pp. 1206-1212
    • Fallarino, F.1    Grohmann, U.2    Hwang, K.W.3
  • 54
    • 5644302161 scopus 로고    scopus 로고
    • Human T regulatory cells can use the perforin pathway to cause autologous target cell death
    • GROSSMAN WJ, VERBSKY JW, BARCHET W, COLONNA M, ATKINSON JP, LEY TJ: Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity. (2004) 21:589-601.
    • (2004) Immunity , vol.21 , pp. 589-601
    • Grossman, W.J.1    Verbsky, J.W.2    Barchet, W.3    Colonna, M.4    Atkinson, J.P.5    Ley, T.J.6
  • 55
    • 20944444896 scopus 로고    scopus 로고
    • Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T cells
    • YOU S, BELGHITH M, COBBOLD S et al.: Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T cells. Diabetes. (2005) 54:1415-1422.
    • (2005) Diabetes , vol.54 , pp. 1415-1422
    • You, S.1    Belghith, M.2    Cobbold, S.3
  • 56
    • 0033970953 scopus 로고    scopus 로고
    • + T cells that prevent diabetes onset in nonobese diabetic mice
    • + T cells that prevent diabetes onset in nonobese diabetic mice. J. Immunol. (2000) 164:240-247.
    • (2000) J. Immunol. , vol.164 , pp. 240-247
    • Lepault, F.1    Gagnerault, M.C.2
  • 58
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin-10 in the function of regulatory T cells that inhibit intestinal inflammation
    • ASSEMAN C, MAUZE S, LEACH MW, COFFMAN RL, POWRIE F: An essential role for interleukin-10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. (1999) 190:995-1004.
    • (1999) J. Exp. Med. , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 61
    • 0036732461 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
    • AKBARI O, FREEMAN GJ, MEYER EH et al.: Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat. Med. (2002) 8:1024-1032.
    • (2002) Nat. Med. , vol.8 , pp. 1024-1032
    • Akbari, O.1    Freeman, G.J.2    Meyer, E.H.3
  • 63
    • 0036467522 scopus 로고    scopus 로고
    • + regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses
    • + regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. (2002) 168:1080-1086.
    • (2002) J. Immunol. , vol.168 , pp. 1080-1086
    • Kingsley, C.I.1    Karim, M.2    Bushell, A.R.3    Wood, K.J.4
  • 64
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • O'GARRA A, VIEIRA P: Regulatory T cells and mechanisms of immune system control. Nat. Med. (2004) 10:801-805.
    • (2004) Nat. Med. , vol.10 , pp. 801-805
    • O'Garra, A.1    Vieira, P.2
  • 66
    • 3042703866 scopus 로고    scopus 로고
    • TGF-β: The perpetrator of immune suppression by regulatory T cells and suicidal T cell
    • WAHL SM, SWISHER J, McCARTNEY-FRANCIS N, CHEN W: TGF-β: the perpetrator of immune suppression by regulatory T cells and suicidal T cell. J. Leuk. Biol. (2004) 76:15-24.
    • (2004) J. Leuk. Biol. , vol.76 , pp. 15-24
    • Wahl, S.M.1    Swisher, J.2    Mccartney-Francis, N.3    Chen, W.4
  • 67
    • 16244390854 scopus 로고    scopus 로고
    • Regulatory T cells and autoimmune disease
    • PAUST S, CANTOR H: Regulatory T cells and autoimmune disease. Immunol. Rev. (2005) 204:195-207.
    • (2005) Immunol. Rev. , vol.204 , pp. 195-207
    • Paust, S.1    Cantor, H.2
  • 72
    • 1642321982 scopus 로고    scopus 로고
    • IL-2, regulatory T cells, and tolerance
    • NELSON BH: IL-2, regulatory T cells, and tolerance. J. Immunol. (2004) 172:3983-3988.
    • (2004) J. Immunol. , vol.172 , pp. 3983-3988
    • Nelson, B.H.1
  • 73
    • 4544241811 scopus 로고    scopus 로고
    • Tolerance, not immunity, crucially depends on IL-2
    • MALEK TR, BAYER AL: Tolerance, not immunity, crucially depends on IL-2. Nat. Rev. Immunol. (2004) 4:665-674.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 665-674
    • Malek, T.R.1    Bayer, A.L.2
  • 75
    • 15444374646 scopus 로고    scopus 로고
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. (2005) 201:723-735.
    • (2005) J. Exp. Med. , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 76
    • 4344657757 scopus 로고    scopus 로고
    • + cells controlling a pathogenic CD4 response inhibit cyrokine differentiation, CXCR-3 expression and tissue invasion
    • + cells controlling a pathogenic CD4 response inhibit cyrokine differentiation, CXCR-3 expression and tissue invasion. J. Immunol. (2004) 173:2942-2951.
    • (2004) J. Immunol. , vol.173 , pp. 2942-2951
    • Sarween, N.1    Chodos, A.2    Raykundalia, C.3
  • 80
    • 20444414184 scopus 로고    scopus 로고
    • + regulatory T cells impaired for intestinal homing can prevent colitis
    • + regulatory T cells impaired for intestinal homing can prevent colitis. J. Immunol. (2005) 174:7487-7491.
    • (2005) J. Immunol. , vol.174 , pp. 7487-7491
    • Denning, T.L.1    Kim, G.2    Kronenberg, M.3
  • 81
    • 0038631849 scopus 로고    scopus 로고
    • Type 1 T regulatory cells: Their role in the control of immune responses
    • GROUX H: Type 1 T regulatory cells: Their role in the control of immune responses. Transplantation (2003) 75:8S-12S.
    • (2003) Transplantation , vol.75
    • Groux, H.1
  • 83
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • GRACA L, COBBOLD SP, WALDMANN: Identification of regulatory T cells in tolerated allografts. J. Exp. Med. (2002) 195:1641-1646.
    • (2002) J. Exp. Med. , vol.195 , pp. 1641-1646
    • Graca, L.1    Cobbold, S.P.2    Waldmann3
  • 84
    • 0032864809 scopus 로고    scopus 로고
    • Recombinant human granulocyte colony-stimulating factor (rhG-CSF): Effects on lymphocyte phenotype and function
    • RUTELLA S, RUMI C, SICA S, LEONE G: Recombinant human granulocyte colony-stimulating factor (rhG-CSF): effects on lymphocyte phenotype and function. J. Interf. Cytok. Res. (1999) 19:989-994.
    • (1999) J. Interf. Cytok. Res. , vol.19 , pp. 989-994
    • Rutella, S.1    Rumi, C.2    Sica, S.3    Leone, G.4
  • 85
    • 0035871681 scopus 로고    scopus 로고
    • Postgrafting administration of granulocyte colony-stimulating factor impairs functional immune recovery in recipients of human leukocyte antigen haplotype-mismatched hematopoietic transplants
    • VOLPI I, PERRUCCIO K, TOSTI A et al.: Postgrafting administration of granulocyte colony-stimulating factor impairs functional immune recovery in recipients of human leukocyte antigen haplotype-mismatched hematopoietic transplants. Blood. (2001) 97:2514-2521.
    • (2001) Blood , vol.97 , pp. 2514-2521
    • Volpi, I.1    Perruccio, K.2    Tosti, A.3
  • 86
    • 0035070370 scopus 로고    scopus 로고
    • T-cell apoptosis induced by granulocyte colony-stimulating factor (G-CSF) is associated with retinoblastoma protein phosphorylation and reduced expression of cyclin-dependent kinase inhibitors
    • RUTELLA S, PIERELLI L, RUMI C et al.: T-cell apoptosis induced by granulocyte colony-stimulating factor (G-CSF) is associated with retinoblastoma protein phosphorylation and reduced expression of cyclin-dependent kinase inhibitors. Exp. Hematol. (2001) 29:401-415.
    • (2001) Exp. Hematol. , vol.29 , pp. 401-415
    • Rutella, S.1    Pierelli, L.2    Rumi, C.3
  • 87
    • 0031722397 scopus 로고    scopus 로고
    • Serum of healthy donors receiving recombinant human granulocyte colony-stimulating factor (rhG-CSF) induces T-cell unresponsiveness
    • RUTELLA S, RUMI C, LUCIA MB, SICA S, CAUDA R, LEONE G: Serum of healthy donors receiving recombinant human granulocyte colony-stimulating factor (rhG-CSF) induces T-cell unresponsiveness. Exp. Hematol. (1998) 26:1024-1033.
    • (1998) Exp. Hematol. , vol.26 , pp. 1024-1033
    • Rutella, S.1    Rumi, C.2    Lucia, M.B.3    Sica, S.4    Cauda, R.5    Leone, G.6
  • 88
    • 0037818348 scopus 로고    scopus 로고
    • G-CSF as immune regulator in T cells expressing the G-CSF receptor: Implications for transplantation and autoimmune diseases
    • FRANZKE A, PIAO W, LAUBER J et al.: G-CSF as immune regulator in T cells expressing the G-CSF receptor: implications for transplantation and autoimmune diseases. Blood (2003) 102:734-739.
    • (2003) Blood , vol.102 , pp. 734-739
    • Franzke, A.1    Piao, W.2    Lauber, J.3
  • 89
    • 0036786347 scopus 로고    scopus 로고
    • Role for granulocyte colony-stimulating factor in the generation of human T regulatory Type 1 cells
    • RUTELLA S, PIERELLI L, BONANNO G et al.: Role for granulocyte colony-stimulating factor in the generation of human T regulatory Type 1 cells. Blood (2002) 100:2562-2571.
    • (2002) Blood , vol.100 , pp. 2562-2571
    • Rutella, S.1    Pierelli, L.2    Bonanno, G.3
  • 90
    • 2942753928 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor promotes the generation of regulatory DCs through induction of IL-10 and IFN-α
    • RUTELLA S, BONANNO G, PIERELLI L et al.: Granulocyte colony-stimulating factor promotes the generation of regulatory DCs through induction of IL-10 and IFN-α. Eur. J. Immunol. (2004) 34:1291-1302.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 1291-1302
    • Rutella, S.1    Bonanno, G.2    Pierelli, L.3
  • 91
    • 1942425058 scopus 로고    scopus 로고
    • Donor treatment with pegylated G-CSF augments the generation of IL-10-producing regulatory T cells and promotes transplantation tolerance
    • MORRIS ES, MACDONALD KPA, ROWE V et al.: Donor treatment with pegylated G-CSF augments the generation of IL-10-producing regulatory T cells and promotes transplantation tolerance. Blood (2004) 103:3573-3581.
    • (2004) Blood , vol.103 , pp. 3573-3581
    • Morris, E.S.1    Macdonald, K.P.A.2    Rowe, V.3
  • 92
    • 0842321793 scopus 로고    scopus 로고
    • + T regulatory cells that can suppress ongoing experimental autoimmune encephalomyelitis
    • + T regulatory cells that can suppress ongoing experimental autoimmune encephalomyelitis. J. Immunol. (2004) 172:1991-1995.
    • (2004) J. Immunol. , vol.172 , pp. 1991-1995
    • Faunce, D.E.1    Terajevacz, A.2    Stein-Streilein, J.3
  • 93
    • 0036838536 scopus 로고    scopus 로고
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • + regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. (2002) 169:4712-4716.
    • (2002) J. Immunol. , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 97
    • 4644301368 scopus 로고    scopus 로고
    • Association of FoxP3 regulatory gene expression with graft-versus-host disease
    • MIURA Y, THOBURN CJ, BRIGHT EC et al.: Association of FoxP3 regulatory gene expression with graft-versus-host disease. Blood. (2004) 104:2187-2193.
    • (2004) Blood , vol.104 , pp. 2187-2193
    • Miura, Y.1    Thoburn, C.J.2    Bright, E.C.3
  • 99
    • 27144500976 scopus 로고    scopus 로고
    • + regulatory T cells in patients with chronic graft-versus-host disease
    • + regulatory T cells in patients with chronic graft-versus-host disease. Blood (2005) 106:2903-2911.
    • (2005) Blood , vol.106 , pp. 2903-2911
    • Zorn, E.1    Kim, H.T.2    Lee, S.J.3
  • 100
    • 17244378876 scopus 로고    scopus 로고
    • + regulatory T cells in vitro: A novel defect of T cell regulation in systemic lupus erythematosus
    • + regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus. Arth. Rheum. (2005) 52:1180-1184.
    • (2005) Arth. Rheum. , vol.52 , pp. 1180-1184
    • Monk, C.R.1    Spachidou, M.2    Rovis, F.3
  • 101
    • 23244463009 scopus 로고    scopus 로고
    • + T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis
    • + T cells from lupus-prone mice to suppress lupus glomerulonephritis and sialoadenitis. J. Immunol. (2005) 175:944-950.
    • (2005) J. Immunol. , vol.175 , pp. 944-950
    • Bagavant, H.1    Tung, K.S.2
  • 102
    • 1842681797 scopus 로고    scopus 로고
    • + T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen
    • + T cells permits the development of spontaneous lupus-like disease in mice, and can be reversed by induction of mucosal tolerance to histone peptide autoantigen. Lupus (2004) 13:192-200.
    • (2004) Lupus , vol.13 , pp. 192-200
    • Wu, H.Y.1    Staines, N.A.2
  • 103
    • 1342267617 scopus 로고    scopus 로고
    • + T cells in peripheral blood of patients with systemic lupus erythematosus
    • + T cells in peripheral blood of patients with systemic lupus erythematosus. Scand. J. Immunol. (2004) 59:198-202.
    • (2004) Scand. J. Immunol. , vol.59 , pp. 198-202
    • Liu, M.F.1    Wang, C.R.2    Fung, L.L.3    Wu, C.R.4
  • 104
    • 0035985790 scopus 로고    scopus 로고
    • The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases
    • HORWITZ DA, GRAY JD, ZHENG SG: The potential of human regulatory T cells generated ex vivo as a treatment for lupus and other chronic inflammatory diseases. Arthritis Res. (2002) 4:241-246.
    • (2002) Arthritis Res. , vol.4 , pp. 241-246
    • Horwitz, D.A.1    Gray, J.D.2    Zheng, S.G.3
  • 105
    • 0031781603 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Etiology and pathogenesis
    • FIOCCHI C: Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology (1998) 115:182-205.
    • (1998) Gastroenterology , vol.115 , pp. 182-205
    • Fiocchi, C.1
  • 106
    • 4644275197 scopus 로고    scopus 로고
    • Regulatory T cells: Peace keepers in the gut
    • ALLEZ M, MAYER L: Regulatory T cells: peace keepers in the gut. Inflamm. Bowel Dis. (2004) 10:666-676.
    • (2004) Inflamm. Bowel Dis. , vol.10 , pp. 666-676
    • Allez, M.1    Mayer, L.2
  • 109
    • 0036080009 scopus 로고    scopus 로고
    • Regulation of mucosal immune responses by recombinant interleukin 10 produced by intestinal epithelial cells in mice
    • DE WINTER H, ELEWAUT D, TUROVSKAYA O et al.: Regulation of mucosal immune responses by recombinant interleukin 10 produced by intestinal epithelial cells in mice. Gastroenterology (2002) 122:1829-1841.
    • (2002) Gastroenterology , vol.122 , pp. 1829-1841
    • De Winter, H.1    Elewaut, D.2    Turovskaya, O.3
  • 111
    • 0036883901 scopus 로고    scopus 로고
    • Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    • CONG Y, WEAVER CT, LAZENBY A, ELSON CO.: Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J. Immunol. (2002) 169:6112-6119.
    • (2002) J. Immunol. , vol.169 , pp. 6112-6119
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3    Elson, C.O.4
  • 112
    • 0036151001 scopus 로고    scopus 로고
    • Microflora reactive IL-10 producing regulatory T cells are present in the colon of IL-2 deficient mice but lack efficacious inhibition of IFN-γ and TNF-α production
    • WAIDMANN M, ALLEMAND Y, LEHMANN J et al.: Microflora reactive IL-10 producing regulatory T cells are present in the colon of IL-2 deficient mice but lack efficacious inhibition of IFN-γ and TNF-α production. Gut. (2002) 50:170-179.
    • (2002) Gut , vol.50 , pp. 170-179
    • Waidmann, M.1    Allemand, Y.2    Lehmann, J.3
  • 113
    • 0037136284 scopus 로고    scopus 로고
    • + T regulatory cells suppress helicobacter hepaticus-induced colitis
    • + T regulatory cells suppress helicobacter hepaticus-induced colitis. J. Exp. Med. (2002) 196:505-515.
    • (2002) J. Exp. Med. , vol.196 , pp. 505-515
    • Kullberg, M.C.1    Jankovic, D.2    Gorelick, P.L.3
  • 114
    • 0029995799 scopus 로고    scopus 로고
    • Experimental granulomatous colitis in mice is abrogated by induction of TGF-β-mediated oral tolerance
    • NEURATH MF, FUSS I, KELSALL BL, PRESKY DH, WAEGELL W, STROBER W: Experimental granulomatous colitis in mice is abrogated by induction of TGF-β-mediated oral tolerance. J. Exp. Med. (1996) 183:2605-2616.
    • (1996) J. Exp. Med. , vol.183 , pp. 2605-2616
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Presky, D.H.4    Waegell, W.5    Strober, W.6
  • 115
    • 0037080032 scopus 로고    scopus 로고
    • The interrelated roles of TGF-β and IL-10 in the regulation of experimental colitis
    • FUSS IJ, BOIRIVANT M, LACY B, STROBER W: The interrelated roles of TGF-β and IL-10 in the regulation of experimental colitis. J. Immunol. (2002) 168:900-908.
    • (2002) J. Immunol. , vol.168 , pp. 900-908
    • Fuss, I.J.1    Boirivant, M.2    Lacy, B.3    Strober, W.4
  • 116
    • 0032538915 scopus 로고    scopus 로고
    • Oxazolone colitis: A murine model of T helper cell Type 2 colitis treatable with antibodies to interleukin 4
    • BOIRIVANT M, FUSS IJ, CHU A, STROBER W: Oxazolone colitis: a murine model of T helper cell Type 2 colitis treatable with antibodies to interleukin 4. J. Exp. Med. (1998) 188:1929-1939.
    • (1998) J. Exp. Med. , vol.188 , pp. 1929-1939
    • Boirivant, M.1    Fuss, I.J.2    Chu, A.3    Strober, W.4
  • 117
    • 4344682025 scopus 로고    scopus 로고
    • bright T cells in human intestinal lamina propria as regulatory cells
    • bright T cells in human intestinal lamina propria as regulatory cells. J. Immunol. (2004) 173:3119-3130.
    • (2004) J. Immunol. , vol.173 , pp. 3119-3130
    • Makita, S.1    Kanai, T.2    Oshima, S.3
  • 121
    • 0036196305 scopus 로고    scopus 로고
    • + Treg cells: Highly potent regulators of diabetes that require TRANCE-RANK signals
    • + Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity (2002) 16:183-191.
    • (2002) Immunity , vol.16 , pp. 183-191
    • Green, E.A.1    Choi, Y.2    Flavell, R.A.3
  • 124
    • 2442535915 scopus 로고    scopus 로고
    • Type I regulatory T cells specific for desmoglein 3 are more frequently detected in healthy individuals than in patients with pemphigus vulgaris
    • VELDMAN C, HOHNE A, DIECKMANN D, SCHULER G, HERTL M: Type I regulatory T cells specific for desmoglein 3 are more frequently detected in healthy individuals than in patients with pemphigus vulgaris. J. Immunol. (2004) 172:6468-6475.
    • (2004) J. Immunol. , vol.172 , pp. 6468-6475
    • Veldman, C.1    Hohne, A.2    Dieckmann, D.3    Schuler, G.4    Hertl, M.5
  • 125
    • 18244383057 scopus 로고    scopus 로고
    • + regulatory T cells control induction of autoimmune hemolytic anemia
    • + regulatory T cells control induction of autoimmune hemolytic anemia. Blood (2005) 105:3746-3748.
    • (2005) Blood , vol.105 , pp. 3746-3748
    • Mqadmi, A.1    Zheng, X.2    Yazdanbakhsh, K.3
  • 126
    • 10844222790 scopus 로고    scopus 로고
    • high regulatory T cells in psoriasis: Mechanism underlying unrestrained pathogenic effector T cell proliferation
    • high regulatory T cells in psoriasis: Mechanism underlying unrestrained pathogenic effector T cell proliferation. J. Immunol. (2005) 174:164-173.
    • (2005) J. Immunol. , vol.174 , pp. 164-173
    • Sugiyama, H.1    Gyulai, R.2    Toichi, E.3
  • 129
    • 2442618129 scopus 로고    scopus 로고
    • bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis
    • bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis. J. Immunol. (2004) 172:6435-6443.
    • (2004) J. Immunol. , vol.172 , pp. 6435-6443
    • De Kleer, I.M.1    Wedderburn, L.R.2    Taams, L.S.3
  • 131
    • 18944379171 scopus 로고    scopus 로고
    • + regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis
    • + regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis. J. Immunol. (2005) 174:7006-7013.
    • (2005) J. Immunol. , vol.174 , pp. 7006-7013
    • Gangi, E.1    Vasu, C.2    Cheatem, D.3    Prabhakar, B.S.4
  • 134
    • 0038434099 scopus 로고    scopus 로고
    • Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
    • GAMBINERI E, TORGERSON TR, OCHS HD: Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr. Opin. Rheumatol. (2003) 15:430-435.
    • (2003) Curr. Opin. Rheumatol. , vol.15 , pp. 430-435
    • Gambineri, E.1    Torgerson, T.R.2    Ochs, H.D.3
  • 135
    • 0035167967 scopus 로고    scopus 로고
    • The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
    • BENNETT CL, CHRISTIE J, RAMSDELL F et al.: The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genetics (2001) 27:20-21.
    • (2001) Nat. Genetics , vol.27 , pp. 20-21
    • Bennett, C.L.1    Christie, J.2    Ramsdell, F.3
  • 136
    • 0035821985 scopus 로고    scopus 로고
    • Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation
    • BAUD O, GOULET O, CANIONI D et al.: Treatment of the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) by allogeneic bone marrow transplantation. New Engl. J. Med. (2001) 344:1758-1762.
    • (2001) New Engl. J. Med. , vol.344 , pp. 1758-1762
    • Baud, O.1    Goulet, O.2    Canioni, D.3
  • 137
    • 19044382961 scopus 로고    scopus 로고
    • A new case of IPEX receiving bone marrow transplantation
    • MAZZOLARI E, FORINO C, FONTANA M et al.: A new case of IPEX receiving bone marrow transplantation. Bone Marrow Transplant. (2005) 35:1033-1034.
    • (2005) Bone Marrow Transplant. , vol.35 , pp. 1033-1034
    • Mazzolari, E.1    Forino, C.2    Fontana, M.3
  • 138
    • 13144261691 scopus 로고    scopus 로고
    • FOXP3 acts as a rheostat of the immune response
    • OCHS HD, ZIEGLER SF, TORGERSON TR: FOXP3 acts as a rheostat of the immune response. Immunol. Rev. (2005) 203:156-164.
    • (2005) Immunol. Rev. , vol.203 , pp. 156-164
    • Ochs, H.D.1    Ziegler, S.F.2    Torgerson, T.R.3
  • 139
    • 0043246615 scopus 로고    scopus 로고
    • Rescue of the autoimmune scurfy mouse by partial bone marrow transplantation or by injection with T-entiched splenocytes
    • SMYK-PEARSON SK, BAKKE AC, HELD PK, WILDIN RS: Rescue of the autoimmune scurfy mouse by partial bone marrow transplantation or by injection with T-entiched splenocytes. Clin. Exp. Immunol. (2003) 133:193-199.
    • (2003) Clin. Exp. Immunol. , vol.133 , pp. 193-199
    • Smyk-Pearson, S.K.1    Bakke, A.C.2    Held, P.K.3    Wildin, R.S.4
  • 140
    • 0036687184 scopus 로고    scopus 로고
    • Growth and expansion of human T regulatory Type 1 cells are independent from TCR activation but require exogenous cytokines
    • BACCHETTA R, SARTIRANA C, LEVINGS MK, BORDIGNON C, NARULA S, RONCAROLO MG: Growth and expansion of human T regulatory Type 1 cells are independent from TCR activation but require exogenous cytokines. Eur. J. Immunol. (2002) 32:2237-2245.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 2237-2245
    • Bacchetta, R.1    Sartirana, C.2    Levings, M.K.3    Bordignon, C.4    Narula, S.5    Roncarolo, M.G.6
  • 143
    • 2942642383 scopus 로고    scopus 로고
    • In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
    • TANG Q, HENRIKSEN KJ, BI M et al.: In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J. Exp. Med. (2004) 199:1455-1465.
    • (2004) J. Exp. Med. , vol.199 , pp. 1455-1465
    • Tang, Q.1    Henriksen, K.J.2    Bi, M.3
  • 145
    • 0037026001 scopus 로고    scopus 로고
    • + immunoregulatory T cells: New therapeutics for graft-versus-host disease after allogeneic bone marrow transplantation
    • + immunoregulatory T cells: New therapeutics for graft-versus-host disease after allogeneic bone marrow transplantation. J. Exp. Med. (2002) 196:401-406.
    • (2002) J. Exp. Med. , vol.196 , pp. 401-406
    • Cohen, J.L.1    Trenado, A.2    Vasey, D.3    Klatzmann, D.4    Salomon, B.L.5
  • 146
    • 0037093217 scopus 로고    scopus 로고
    • + immune regulatory cells inhibits graft-versus-host disease lethality
    • + immune regulatory cells inhibits graft-versus-host disease lethality. Blood. (2002) 99:3493-3499.
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 147
    • 0037025943 scopus 로고    scopus 로고
    • + regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation
    • + regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation. J. Exp. Med. (2002) 196:389-399.
    • (2002) J. Exp. Med. , vol.196 , pp. 389-399
    • Hoffmann, P.1    Ermann, J.2    Edinger, M.3    Fathman, C.G.4    Strober, S.5
  • 148
    • 0141461418 scopus 로고    scopus 로고
    • + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat. Med. (2003) 9:1144-1150.
    • (2003) Nat. Med. , vol.9 , pp. 1144-1150
    • Edinger, M.1    Hoffman, P.2    Ermann, J.3
  • 149
    • 0346690399 scopus 로고    scopus 로고
    • + regulatory T cells favor immune reconstitution control graft-versus-host disease while maintaining graft-versus-leukemia
    • + regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J. Clin. Invest. (2003) 112:1688-1696.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1688-1696
    • Trenado, A.1    Charlotte, F.2    Fisson, S.3
  • 150
    • 0037339812 scopus 로고    scopus 로고
    • Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse
    • SATO K, YAMASHITA N, YAMASHITA N, MASANORI B, MATSUYAMA T: Regulatory dendritic cells protect mice from murine acute graft-versus-host disease and leukemia relapse. Immunity (2003) 18:367-379.
    • (2003) Immunity , vol.18 , pp. 367-379
    • Sato, K.1    Yamashita, N.2    Yamashita, N.3    Masanori, B.4    Matsuyama, T.5
  • 151
    • 0012391130 scopus 로고    scopus 로고
    • Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells
    • SATO K, YAMASHITA N, BABA M, MATSUYAMA T: Modified myeloid dendritic cells act as regulatory dendritic cells to induce anergic and regulatory T cells. Blood (2003) 101:3581-3589.
    • (2003) Blood , vol.101 , pp. 3581-3589
    • Sato, K.1    Yamashita, N.2    Baba, M.3    Matsuyama, T.4
  • 152
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: Friend or foe in immunity to infection?
    • MILLS KH: Regulatory T cells: friend or foe in immunity to infection? Nat. Rev. Immunol. (2004) 4:1-15.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 1-15
    • Mills, K.H.1
  • 153
    • 1542309563 scopus 로고    scopus 로고
    • Immunoregulatory T cells in tumor immunity
    • TERABE M, BERZOFSKY JA: Immunoregulatory T cells in tumor immunity. Curr. Opin. Immunol. (2004) 16:157-162.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 157-162
    • Terabe, M.1    Berzofsky, J.A.2
  • 154
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • CURIEL TJ, COUKOS G, LINHUA Z et al.: Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. (2004) 10:942-949.
    • (2004) Nat. Med. , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Linhua, Z.3
  • 156
    • 0033571105 scopus 로고    scopus 로고
    • + T cells: A common basis between tumor immunity and autoimmunity
    • + T cells: a common basis between tumor immunity and autoimmunity. J. Immunol. (1999) 163:5211-5218.
    • (1999) J. Immunol. , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 158
    • 20444464066 scopus 로고    scopus 로고
    • + T regulatory cell activities in lung cancer
    • + T regulatory cell activities in lung cancer. Cancer Res. (2005) 65:5211-5220.
    • (2005) Cancer Res. , vol.65 , pp. 5211-5220
    • Sharma, S.1    Yang, S.2    Zhu, L.3
  • 159
    • 3042838753 scopus 로고    scopus 로고
    • + regulatory T cells, in adult T-cell leukaemia/lymphoma cells
    • + regulatory T cells, in adult T-cell leukaemia/lymphoma cells. Br. J. Haematol (2004) 126:81-84.
    • (2004) Br. J. Haematol. , vol.126 , pp. 81-84
    • Karube, K.1    Ohshima, K.2    Tsuchiya, T.3
  • 160
    • 9344251670 scopus 로고    scopus 로고
    • The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-cell leukemia/lymphoma
    • ISHIDA T, IIDA S, AKATSUKA Y et al.: The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-cell leukemia/lymphoma. Clin. Cancer Res. (2004) 10:7529-7539.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 7529-7539
    • Ishida, T.1    Iida, S.2    Akatsuka, Y.3
  • 161
    • 0030822084 scopus 로고    scopus 로고
    • Inhibition of lymphocyte blastogenic response in healthy donors treated with recombinant human granulocyte colony-stimulating factor (rhG-CSF): Possible role of lactoferrin and interleukin-1 receptor antagonist
    • RUTELLA S, RUMI C, TESTA U et al.: Inhibition of lymphocyte blastogenic response in healthy donors treated with recombinant human granulocyte colony-stimulating factor (rhG-CSF): possible role of lactoferrin and interleukin-1 receptor antagonist. Bone Marrow Transplant. (1997) 20:355-364.
    • (1997) Bone Marrow Transplant , vol.20 , pp. 355-364
    • Rutella, S.1    Rumi, C.2    Testa, U.3
  • 162
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • MALOY KJ, POWRIE F: Regulatory T cells in the control of immune pathology. Nat. Immunol. (2001) 2:816-822.
    • (2001) Nat. Immunol. , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 163
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • WOOD KJ, SAKAGUCHI S: Regulatory T cells in transplantation tolerance. Nat. Rev. Immunol. (2003) 3:199-210.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 164
    • 0035806323 scopus 로고    scopus 로고
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. (2001) 193:1295-1302.
    • (2001) J. Exp. Med. , vol.193 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 165
    • 17844376787 scopus 로고    scopus 로고
    • + regulatory T cells for the treatment of inflammatory bowel diseases
    • + regulatory T cells for the treatment of inflammatory bowel diseases. Expert Opin. Biol. Ther. (2005) 5:451-462.
    • (2005) Expert Opin. Biol. Ther. , vol.5 , pp. 451-462
    • Kanai, T.1    Watanabe, M.2
  • 167
    • 22144475453 scopus 로고    scopus 로고
    • Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FoxP3 in human T cells
    • BAAN CC, VAN DER MAST BJ, KLEPPER M et al.: Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FoxP3 in human T cells. Transplantation (2005) 80:110-117.
    • (2005) Transplantation , vol.80 , pp. 110-117
    • Baan, C.C.1    Van Der Mast, B.J.2    Klepper, M.3
  • 169
    • 10744228165 scopus 로고    scopus 로고
    • Favorably tipping the balance between cytophatic and regulatory T cells to create transplantation tolerance
    • ZHENG XX, SANCHEZ-FUEYO A, SHO M, DOMENIC C, SAYEGH MH, STROM TB: Favorably tipping the balance between cytophatic and regulatory T cells to create transplantation tolerance. Immunity (2003) 19:503-514.
    • (2003) Immunity , vol.19 , pp. 503-514
    • Zheng, X.X.1    Sanchez-Fueyo, A.2    Sho, M.3    Domenic, C.4    Sayegh, M.H.5    Strom, T.B.6


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