Decreased CD4+CD25+ T Cells in Peripheral Blood of Patients with Systemic Lupus Erythematosus

Scandinavian Journal of Immunology

Volumn 59, Issue 2, 2004, Pages 198-202

  Liu, M F ^a,b   Wang, C R ^a   Fung, L L ^a   Wu, C R ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; INTERLEUKIN 2 RECEPTOR;

ARTICLE; BLOOD; BLOOD ANALYSIS; CELL COUNT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOLOGY; INTERMETHOD COMPARISON; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MOLECULAR BIOLOGY; MONONUCLEAR CELL; NONPARAMETRIC TEST; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

CD4-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; HUMANS; LEUKOCYTE COUNT; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; RECEPTORS, INTERLEUKIN-2; STATISTICS, NONPARAMETRIC;

EID: 1342267617     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0300-9475.2004.01370.x     Document Type: Article

References (29)

1. + regulatory T cells in autoimmunity and allergy. Curr Opin Immunol 2002;14:771-8.
2. Shevach EM. Regulatory T cells in autoimmunity. Annu Rev Immunol 2000;18:423-49.
3. Sakaguchi S, Sakaguchi N, Asano M et al. Immunologic self-tolerance maintained by activated T cells expressing Il-2 receptor alpha-chains (CD25). Breakdown of single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995;155:1151-64.
4. Asano M, Toda M, Sakaguchi S. Autoimmune disease as a consequence of developmental abnormality of a T-cell subpopulation. J Exp Med 1996;184:387-96.
5. + immunoregulatory T cells suppress polyclonal T-cell activation in vitro by inhibiting interlukin-2 production. J Exp Med 1998;188:287-96.
6. + naturally anergic and suppressive T cells. Int Immunol 1998;10:1969-80.
7. +CD45Rblow T cells: a population of T cells with immune regulatory activities. Eur J Immunol 1998;28:3453-47.
8. Nishizuka Y, Sakakura T. Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 1969;166:753-5.
9. Kojima A, Tanaka-Kojima Y, Sakakura T et al. Prevention of post-thymectomy autoimmune thyroidtis in mice. Lab Invest 1976;34:601-5.
10. Kojima A, Taguchi O, Nishizuka Y. Experimental production of possible autoimmune gastritis followed by macrocytic anemia in athymic nude mice. Lab Invest 1980;42:387-95.
11. Sakaguchi S, Takahashi T, Nishizuka Y. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocyte damage after adoptive transfer. J Exp Med 1982;156:1565-76.
12. Sakaguchi S, Takahasi T, Nishizuka Y. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J Exp Med 1982;156:1577-86.
13. + cells: a naturally occurring population of regulatory T cells. Blood 2001;98:2736-44.
14. + T cells with regulatory properties from human blood J Exp Med 2001;193:1303-11.
15. + regulator cells in human peripheral blood. J Immunol 2001;167:1245-53.
16. + T cells with regulatory properties isolated from peripheral blood. J Exp Med 2001;193:1285-94.
17. + thymocytes and peripheral T cells have immune suppressive activity. Eur J Immunol 2001;31:1247-54.
18. Bombardier C, Gladman DD, Urowitz MB et al. Committee on prognosis studies in SLE. Derivation of the SLEDAI. Arthritis Rheum 1992;35:630-40.
19. + T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int Immunol 2000;12:1145-55.
20. + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998;188:287-96.
21. Asseman C, Mauze S, Leach MW et al. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 1999;190:995-1004.
22. + T cells. J Exp Med 1996;183:2669-74.
23. Chen Y, Kuchroo VK, Inobe J et al. Regulatory T cell colonies induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994;265:1237-40.
24. + immunoregulatory cells. J Immunol 2001;167:1137-40.
25. + regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000;192:303-10.
26. + regulatory cells that control intestinal role inflammation. J Exp Med 2000;192:295-302.
27. Bystry RS, Aluvihare V, Welch KA et al. B cells and professional APCs recruit regulatory T cells via CCL4. Nat Immunol 2001;2:1126-32.
28. Seo SJ, Fields ML, Buckler JL et al. The impact of T helper and T regulatory cells on the regulation of anti-double-strand DNA B cells. Immunity 2002;16:535-46.
29. + T cells from the target organ of patients with rheumatoid arthritis. Eur J Immunol 2003;33:215-33.