-
1
-
-
2442647655
-
Functional evidence for a single endodermal origin for the thymic epithelium
-
Gordon J, Wilson VA, Blair NF, Sheridan J, Parley A, Wilson L, Manley NR, Blackburn CC. Functional evidence for a single endodermal origin for the thymic epithelium. Nat Immunol 2004; 5:546-553.
-
(2004)
Nat Immunol
, vol.5
, pp. 546-553
-
-
Gordon, J.1
Wilson, V.A.2
Blair, N.F.3
Sheridan, J.4
Parley, A.5
Wilson, L.6
Manley, N.R.7
Blackburn, C.C.8
-
2
-
-
0028902305
-
Limited development capacity of the earliest embryonic murine thymus
-
Amagai T, Itoi M, Kondo Y. Limited development capacity of the earliest embryonic murine thymus. Eur J Immunol 1995; 25:757-762.
-
(1995)
Eur J Immunol
, vol.25
, pp. 757-762
-
-
Amagai, T.1
Itoi, M.2
Kondo, Y.3
-
3
-
-
0028225854
-
Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro
-
Anderson G, Owen JJ, Moore NC, Jenkinson EJ. Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro. J Exp Med 1994; 179:2027-2031.
-
(1994)
J Exp Med
, vol.179
, pp. 2027-2031
-
-
Anderson, G.1
Owen, J.J.2
Moore, N.C.3
Jenkinson, E.J.4
-
4
-
-
0035898387
-
Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development
-
Lind EF, Prockop SE, Porritt HE, Petrie HT. Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development. J Exp Med 2001; 194:127-134.
-
(2001)
J Exp Med
, vol.194
, pp. 127-134
-
-
Lind, E.F.1
Prockop, S.E.2
Porritt, H.E.3
Petrie, H.T.4
-
5
-
-
0035496231
-
Lymphostromal interactions in thymic development and function
-
Anderson G, Jenkinson EJ. Lymphostromal interactions in thymic development and function. Nat Rev Immunol 2001; 1:31-40.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 31-40
-
-
Anderson, G.1
Jenkinson, E.J.2
-
7
-
-
0035171545
-
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
-
Derbinski J, Schulte A, Kyewski B, Klein L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat Immunol 2001; 2:1032-1039.
-
(2001)
Nat Immunol
, vol.2
, pp. 1032-1039
-
-
Derbinski, J.1
Schulte, A.2
Kyewski, B.3
Klein, L.4
-
9
-
-
0041884736
-
Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR
-
Boehm T, Scheu S, Pfeffer K, Bleul CC. Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. J Exp Med 2003; 198:757-769.
-
(2003)
J Exp Med
, vol.198
, pp. 757-769
-
-
Boehm, T.1
Scheu, S.2
Pfeffer, K.3
Bleul, C.C.4
-
10
-
-
0242624626
-
Lymphotoxin pathway directs thymic Aire expression
-
Chin RK, Lo JC, Kim O, Blink SE, Christiansen PA, Peterson P, Wang Y, Ware C, Fu YX. Lymphotoxin pathway directs thymic Aire expression. Nat Immunol 2003; 4:1121-1127.
-
(2003)
Nat Immunol
, vol.4
, pp. 1121-1127
-
-
Chin, R.K.1
Lo, J.C.2
Kim, O.3
Blink, S.E.4
Christiansen, P.A.5
Peterson, P.6
Wang, Y.7
Ware, C.8
Fu, Y.X.9
-
11
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC. Aire regulates negative selection of organ-specific T cells. Nat Immunol 2003; 4:350-354.
-
(2003)
Nat Immunol
, vol.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
Wilson, J.3
Peltonen, L.4
Goodnow, C.C.5
-
12
-
-
0028000121
-
New member of the winged-helix protein family disrupted in mouse and rat nude mutations
-
Nehls M, Pfeifer D, Schorpp M, Hedrich H, Boehm T. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature 1994; 372:103-107.
-
(1994)
Nature
, vol.372
, pp. 103-107
-
-
Nehls, M.1
Pfeifer, D.2
Schorpp, M.3
Hedrich, H.4
Boehm, T.5
-
13
-
-
0342614209
-
Unified nomenclature for the winged helix/forkhead transcription factors
-
Kaestner KH, Knochel W, Martinez DE. Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev 2000; 14:142-146.
-
(2000)
Genes Dev
, vol.14
, pp. 142-146
-
-
Kaestner, K.H.1
Knochel, W.2
Martinez, D.E.3
-
15
-
-
0015015673
-
Immunological responses of "nude" mice
-
Wortis HH. Immunological responses of "nude" mice. Clin Exp Immunol 1971; 8:305-317.
-
(1971)
Clin Exp Immunol
, vol.8
, pp. 305-317
-
-
Wortis, H.H.1
-
16
-
-
0029999218
-
The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors
-
Blackburn CC, Augustine CL, Li R, Harvey RP, Malin MA, Boyd RL, Miller JF, Morahan G. The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors. Proc Natl Acad Sci U S A 1996; 93:5742-5746.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5742-5746
-
-
Blackburn, C.C.1
Augustine, C.L.2
Li, R.3
Harvey, R.P.4
Malin, M.A.5
Boyd, R.L.6
Miller, J.F.7
Morahan, G.8
-
17
-
-
0029920145
-
Two genetically separable steps in the differentiation of thymic epithelium
-
Nehls M, Kyewski B, Messerle M, Waldschutz R, Schuddekopf K, Smith AJ, Boehm T. Two genetically separable steps in the differentiation of thymic epithelium. Science 1996; 272:886-889.
-
(1996)
Science
, vol.272
, pp. 886-889
-
-
Nehls, M.1
Kyewski, B.2
Messerle, M.3
Waldschutz, R.4
Schuddekopf, K.5
Smith, A.J.6
Boehm, T.7
-
18
-
-
0242624627
-
A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation
-
Su DM, Navarre S, Oh WJ, Condie BG, Manley NR. A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation. Nat Immunol 2003; 4:1128-1135.
-
(2003)
Nat Immunol
, vol.4
, pp. 1128-1135
-
-
Su, D.M.1
Navarre, S.2
Oh, W.J.3
Condie, B.G.4
Manley, N.R.5
-
19
-
-
0037415594
-
Extrathymic T cell lymphopoiesis: Ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice
-
Guy-Grand D, Azogui O, Celli S, Darche S, Nussenzweig MC, Kourilsky P, Vassalli P. Extrathymic T cell lymphopoiesis: ontogeny and contribution to gut intraepithelial lymphocytes in athymic and euthymic mice. J Exp Med 2003; 197:333-341.
-
(2003)
J Exp Med
, vol.197
, pp. 333-341
-
-
Guy-Grand, D.1
Azogui, O.2
Celli, S.3
Darche, S.4
Nussenzweig, M.C.5
Kourilsky, P.6
Vassalli, P.7
-
20
-
-
0029856924
-
Regulation of an extrathymic T-cell development pathway by oncostatin M
-
Clegg CH, Rulffes JT, Wallace PM, Haugen HS. Regulation of an extrathymic T-cell development pathway by oncostatin M. Nature 1996; 384:261-263.
-
(1996)
Nature
, vol.384
, pp. 261-263
-
-
Clegg, C.H.1
Rulffes, J.T.2
Wallace, P.M.3
Haugen, H.S.4
-
21
-
-
0037384857
-
Mammalian twisted gastrulation is essential for skeleto-lymphogenesis
-
Nosaka T, Morita S, Kitamura H, Nakajima H, Shibata F, Morikawa Y, Kataoka Y, Ebihara Y, Kawashima T, Itoh T, Ozaki K, Senba E, Tsuji K, Makishima F, Yoshida N, Kitamura T. Mammalian twisted gastrulation is essential for skeleto-lymphogenesis. Mol Cell Biol 2003; 23:2969-2980.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 2969-2980
-
-
Nosaka, T.1
Morita, S.2
Kitamura, H.3
Nakajima, H.4
Shibata, F.5
Morikawa, Y.6
Kataoka, Y.7
Ebihara, Y.8
Kawashima, T.9
Itoh, T.10
Ozaki, K.11
Senba, E.12
Tsuji, K.13
Makishima, F.14
Yoshida, N.15
Kitamura, T.16
-
22
-
-
0035881543
-
Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb
-
Revest JM, Suniara RK, Kerr K, Owen JJ, Dickson C. Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb. J Immunol 2001; 167:1954-1961.
-
(2001)
J Immunol
, vol.167
, pp. 1954-1961
-
-
Revest, J.M.1
Suniara, R.K.2
Kerr, K.3
Owen, J.J.4
Dickson, C.5
-
23
-
-
0032536823
-
Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning
-
Celli G, LaRochelle WJ, Mackem S, Sharp R, Merlino G. Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J 1998; 17: 1642-1655.
-
(1998)
EMBO J
, vol.17
, pp. 1642-1655
-
-
Celli, G.1
Larochelle, W.J.2
Mackem, S.3
Sharp, R.4
Merlino, G.5
-
24
-
-
0029030722
-
The role of Hoxa-3 in mouse thymus and thyroid development
-
Manley NR, Capecchi MR. The role of Hoxa-3 in mouse thymus and thyroid development. Development 1995; 121:1989-2003.
-
(1995)
Development
, vol.121
, pp. 1989-2003
-
-
Manley, N.R.1
Capecchi, M.R.2
-
25
-
-
0032169255
-
Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities
-
Peters H, Neubuser A, Kratochwil K, Balling R. Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev 1998; 12:2735-2747.
-
(1998)
Genes Dev
, vol.12
, pp. 2735-2747
-
-
Peters, H.1
Neubuser, A.2
Kratochwil, K.3
Balling, R.4
-
26
-
-
0030069119
-
Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation
-
Wallin J, Eibel H, Neubuser A, Wilting J, Koseki H, Balling R. Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation. Development 1996; 122:23-30.
-
(1996)
Development
, vol.122
, pp. 23-30
-
-
Wallin, J.1
Eibel, H.2
Neubuser, A.3
Wilting, J.4
Koseki, H.5
Balling, R.6
-
27
-
-
85012710561
-
Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors
-
Goldschneider I, Komschlies KL, Greiner DL. Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors. J Exp Med 1986; 163:1-17.
-
(1986)
J Exp Med
, vol.163
, pp. 1-17
-
-
Goldschneider, I.1
Komschlies, K.L.2
Greiner, D.L.3
-
28
-
-
0022556206
-
Dynamics of early T cells: Prothymocyte migration and proliferation in the adult mouse thymus
-
Scollay R, Smith J, Stauffer V. Dynamics of early T cells: prothymocyte migration and proliferation in the adult mouse thymus. Immunol Rev 1986; 91:129-157.
-
(1986)
Immunol Rev
, vol.91
, pp. 129-157
-
-
Scollay, R.1
Smith, J.2
Stauffer, V.3
-
29
-
-
0025790455
-
Developmental potential of the earliest precursor cells from the adult mouse thymus
-
Wu L, Antica M, Johnson GR, Scollay R, Shortman K. Developmental potential of the earliest precursor cells from the adult mouse thymus. J Exp Med 1991; 174:1617-1627.
-
(1991)
J Exp Med
, vol.174
, pp. 1617-1627
-
-
Wu, L.1
Antica, M.2
Johnson, G.R.3
Scollay, R.4
Shortman, K.5
-
30
-
-
0042383366
-
Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential
-
Martin CH, Aifantis I, Scimone ML, von Andrian UH, Reizis B, von Boehmer H, Gounari F. Efficient thymic immigration of B220+ lymphoid-restricted bone marrow cells with T precursor potential. Nat Immunol 2003; 4:866-873.
-
(2003)
Nat Immunol
, vol.4
, pp. 866-873
-
-
Martin, C.H.1
Aifantis, I.2
Scimone, M.L.3
Von Andrian, U.H.4
Reizis, B.5
Von Boehmer, H.6
Gounari, F.7
-
31
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997; 91:661-672.
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
32
-
-
0037310525
-
Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors
-
Harman BC, Jenkinson EJ, Anderson G. Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors. J Immunol 2003; 170:1299-1303.
-
(2003)
J Immunol
, vol.170
, pp. 1299-1303
-
-
Harman, B.C.1
Jenkinson, E.J.2
Anderson, G.3
-
33
-
-
0037320932
-
Thymopoiesis independent of common lymphoid progenitors
-
Allman D, Sambandam A, Kim S, Miller JP, Pagan A, Well D, Meraz A, Bhandoola A. Thymopoiesis independent of common lymphoid progenitors. Nat Immunol 2003; 4:168-174.
-
(2003)
Nat Immunol
, vol.4
, pp. 168-174
-
-
Allman, D.1
Sambandam, A.2
Kim, S.3
Miller, J.P.4
Pagan, A.5
Well, D.6
Meraz, A.7
Bhandoola, A.8
-
34
-
-
0032135207
-
Requirement for the thymus in αβ lymphocyte lineage commitment
-
Carlyle JR, Zúñiga-Pflücker JC. Requirement for the thymus in αβ lymphocyte lineage commitment. Immunity 1998; 9:187-197.
-
(1998)
Immunity
, vol.9
, pp. 187-197
-
-
Carlyle, J.R.1
Zúñiga-Pflücker, J.C.2
-
35
-
-
0028122624
-
Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization
-
Rodewald H-R, Kretzschmar K, Takeda S, Hohl C, Dessing M. Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization. EMBO J 1994; 13:4229-4240.
-
(1994)
EMBO J
, vol.13
, pp. 4229-4240
-
-
Rodewald, H.-R.1
Kretzschmar, K.2
Takeda, S.3
Hohl, C.4
Dessing, M.5
-
36
-
-
0037079701
-
Identification of the earliest prethymic bipotent T/NK progenitor in murine fetal liver
-
Douagi I, Colucci F, Di Santo JP, Cumano A. Identification of the earliest prethymic bipotent T/NK progenitor in murine fetal liver. Blood 2002; 99:463-471.
-
(2002)
Blood
, vol.99
, pp. 463-471
-
-
Douagi, I.1
Colucci, F.2
Di Santo, J.P.3
Cumano, A.4
-
37
-
-
0942276841
-
Identification of the earliest prethymic T-cell progenitors in murine fetal blood
-
Ikawa T, Masuda K, Lu M, Minato N, Katsura Y, Kawamoto H. Identification of the earliest prethymic T-cell progenitors in murine fetal blood. Blood 2004; 103:530-537.
-
(2004)
Blood
, vol.103
, pp. 530-537
-
-
Ikawa, T.1
Masuda, K.2
Lu, M.3
Minato, N.4
Katsura, Y.5
Kawamoto, H.6
-
38
-
-
0033681860
-
T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver
-
Kawamoto H, Ikawa T, Ohmura K, Fujimoto S, Katsura Y. T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver. Immunity 2000; 12:441-450.
-
(2000)
Immunity
, vol.12
, pp. 441-450
-
-
Kawamoto, H.1
Ikawa, T.2
Ohmura, K.3
Fujimoto, S.4
Katsura, Y.5
-
39
-
-
4344572135
-
Maintenance of T cell specification and differentiation require recurrent Notch receptor-ligand interactions
-
Schmitt TM, Ciofani M, Petrie HT, Zúñiga-Pflücker JC. Maintenance of T cell specification and differentiation require recurrent Notch receptor-ligand interactions. J Exp Med 2004; 200:469-479.
-
(2004)
J Exp Med
, vol.200
, pp. 469-479
-
-
Schmitt, T.M.1
Ciofani, M.2
Petrie, H.T.3
Zúñiga-Pflücker, J.C.4
-
40
-
-
0030790262
-
Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes
-
Carlyle JR, Michie AM, Furlonger C, Nakano T, Lenardo MJ, Paige CJ, Zúñiga-Pflücker JC. Identification of a novel developmental stage marking lineage commitment of progenitor thymocytes. J Exp Med 1997; 186:173-182.
-
(1997)
J Exp Med
, vol.186
, pp. 173-182
-
-
Carlyle, J.R.1
Michie, A.M.2
Furlonger, C.3
Nakano, T.4
Lenardo, M.J.5
Paige, C.J.6
Zúñiga-Pflücker, J.C.7
-
41
-
-
0034652013
-
Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus
-
Michie AM, Carlyle JR, Schmitt TM, Ljutic B, Cho SK, Fong Q, Zúñiga-Pflücker JC. Clonal characterization of a bipotent T cell and NK cell progenitor in the mouse fetal thymus. J Immunol 2000; 164:1730-1733.
-
(2000)
J Immunol
, vol.164
, pp. 1730-1733
-
-
Michie, A.M.1
Carlyle, J.R.2
Schmitt, T.M.3
Ljutic, B.4
Cho, S.K.5
Fong, Q.6
Zúñiga-Pflücker, J.C.7
-
42
-
-
0033454058
-
Commitment of common T/natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay
-
Ikawa T, Kawamoto H, Fujimoto S, Katsura Y. Commitment of common T/natural killer (NK) progenitors to unipotent T and NK progenitors in the murine fetal thymus revealed by a single progenitor assay. J Exp Med 1999; 190:1617-1626.
-
(1999)
J Exp Med
, vol.190
, pp. 1617-1626
-
-
Ikawa, T.1
Kawamoto, H.2
Fujimoto, S.3
Katsura, Y.4
-
43
-
-
0034879612
-
Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen
-
Medina KL, Garrett KP, Thompson LF, Rossi MI, Payne KJ, Kincade PW. Identification of very early lymphoid precursors in bone marrow and their regulation by estrogen. Nat Immunol 2001; 2:718-724.
-
(2001)
Nat Immunol
, vol.2
, pp. 718-724
-
-
Medina, K.L.1
Garrett, K.P.2
Thompson, L.F.3
Rossi, M.I.4
Payne, K.J.5
Kincade, P.W.6
-
44
-
-
0035182533
-
Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations
-
Weissman IL, Anderson DJ, Gage F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations. Annu Rev Cell Dev Biol 2001; 17:387-403.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 387-403
-
-
Weissman, I.L.1
Anderson, D.J.2
Gage, F.3
-
45
-
-
1842474899
-
L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor
-
Perry SS, Wang H, Pierce LJ, Yang AM, Tsai S, Spangrude GJ. L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor. Blood 2004; 103:2990-2996.
-
(2004)
Blood
, vol.103
, pp. 2990-2996
-
-
Perry, S.S.1
Wang, H.2
Pierce, L.J.3
Yang, A.M.4
Tsai, S.5
Spangrude, G.J.6
-
47
-
-
2942516896
-
Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages
-
Porritt HE, Rumfelt LL, Tabrizifard S, Schmitt TM, Zúñiga- Pflücker JC, Petrie HT. Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages. Immunity 2004; 20:735-745.
-
(2004)
Immunity
, vol.20
, pp. 735-745
-
-
Porritt, H.E.1
Rumfelt, L.L.2
Tabrizifard, S.3
Schmitt, T.M.4
Zúñiga-Pflücker, J.C.5
Petrie, H.T.6
-
48
-
-
14944341196
-
The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage and natural killer, but no B lymphocyte potential
-
Balciunaite G, Ceredig R, Rolink AG. The earliest subpopulation of mouse thymocytes contains potent T, significant macrophage and natural killer, but no B lymphocyte potential. Blood 2005; 105:1930-1936.
-
(2005)
Blood
, vol.105
, pp. 1930-1936
-
-
Balciunaite, G.1
Ceredig, R.2
Rolink, A.G.3
-
49
-
-
0028979458
-
Alpha 6 integrins participate in pro-T cell homing to the thymus
-
Ruiz P, Wiles MV, Imhof BA. Alpha 6 integrins participate in pro-T cell homing to the thymus. Eur J Immunol 1995; 25:2034-2041.
-
(1995)
Eur J Immunol
, vol.25
, pp. 2034-2041
-
-
Ruiz, P.1
Wiles, M.V.2
Imhof, B.A.3
-
50
-
-
0027458058
-
The CD44 expressed on the earliest intrathymic precursor population functions as a thymus homing molecule but does not bind to hyaluronate
-
Wu L, Kincade FW, Shortman K. The CD44 expressed on the earliest intrathymic precursor population functions as a thymus homing molecule but does not bind to hyaluronate. Immunol Lett 1993; 38:69-75.
-
(1993)
Immunol Lett
, vol.38
, pp. 69-75
-
-
Wu, L.1
Kincade, F.W.2
Shortman, K.3
-
51
-
-
0029991362
-
Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins
-
Hirsch E, Iglesias A, Potocnik AJ, Hartmann U, Fassler R. Impaired migration but not differentiation of haematopoietic stem cells in the absence of beta1 integrins. Nature 1996; 380:171-175.
-
(1996)
Nature
, vol.380
, pp. 171-175
-
-
Hirsch, E.1
Iglesias, A.2
Potocnik, A.J.3
Hartmann, U.4
Fassler, R.5
-
52
-
-
0030604540
-
Differential requirements for alpha4 integrins during fetal and adult hematopoiesis
-
Arroyo AG, Yang JT, Rayburn H, Hynes RO. Differential requirements for alpha4 integrins during fetal and adult hematopoiesis. Cell 1996; 85:997-1008.
-
(1996)
Cell
, vol.85
, pp. 997-1008
-
-
Arroyo, A.G.1
Yang, J.T.2
Rayburn, H.3
Hynes, R.O.4
-
53
-
-
0034667809
-
In vivo roles of integrins during leukocyte development and traffic: Insights from the analysis of mice chimeric for alpha 5, alpha v, and alpha 4 integrins
-
Arroyo AG, Taverna D, Whittaker CA, Strauch UG, Bader BL, Rayburn H, Crowley D, Parker CM, Hynes RO. In vivo roles of integrins during leukocyte development and traffic: insights from the analysis of mice chimeric for alpha 5, alpha v, and alpha 4 integrins. J Immunol 2000; 165:4667-475.
-
(2000)
J Immunol
, vol.165
, pp. 4667-5475
-
-
Arroyo, A.G.1
Taverna, D.2
Whittaker, C.A.3
Strauch, U.G.4
Bader, B.L.5
Rayburn, H.6
Crowley, D.7
Parker, C.M.8
Hynes, R.O.9
-
54
-
-
0033120062
-
Factors regulating stem cell recruitment to the fetal thymus
-
Wilkinson B, Owen JJ, Jenkinson EJ. Factors regulating stem cell recruitment to the fetal thymus. J Immunol 1999; 162:3873-3881.
-
(1999)
J Immunol
, vol.162
, pp. 3873-3881
-
-
Wilkinson, B.1
Owen, J.J.2
Jenkinson, E.J.3
-
55
-
-
19944427782
-
Role of CCL21 in recruitment of T precursor cells to fetal thymus
-
Liu C, Ueno T, Kuse S, Saito F, Nitta T, Piali L, Nakano H, Kakiuchi T, Lipp M, Hollander GA, Takahama Y. Role of CCL21 in recruitment of T precursor cells to fetal thymus. Blood 2005; 105:31-39.
-
(2005)
Blood
, vol.105
, pp. 31-39
-
-
Liu, C.1
Ueno, T.2
Kuse, S.3
Saito, F.4
Nitta, T.5
Piali, L.6
Nakano, H.7
Kakiuchi, T.8
Lipp, M.9
Hollander, G.A.10
Takahama, Y.11
-
56
-
-
0028979211
-
Requirement for TNF-alpha and IL-1 alpha in fetal thymocyte commitment and differentiation
-
Zúñiga-Pflücker JC, Di J, Lenardo MJ. Requirement for TNF-alpha and IL-1 alpha in fetal thymocyte commitment and differentiation. Science 1995; 268: 1906-1909.
-
(1995)
Science
, vol.268
, pp. 1906-1909
-
-
Zúñiga-Pflücker, J.C.1
Di, J.2
Lenardo, M.J.3
-
57
-
-
0029097045
-
T-cell lineage commitment and cytokine response of thymic progenitors
-
Moore TA, Zlotnik A. T-cell lineage commitment and cytokine response of thymic progenitors. Blood 1995; 86:1850-1860.
-
(1995)
Blood
, vol.86
, pp. 1850-1860
-
-
Moore, T.A.1
Zlotnik, A.2
-
58
-
-
0029787979
-
Thymic dendritic cell precursors: Relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny
-
Wu L, Li CL, Shortman K. Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny. J Exp Med 1996; 184:903-911.
-
(1996)
J Exp Med
, vol.184
, pp. 903-911
-
-
Wu, L.1
Li, C.L.2
Shortman, K.3
-
59
-
-
0141886221
-
T/NK bipotent progenitors in the thymus retain the potential to generate dendritic cells
-
Shen HQ, Lu M, Ikawa T, Masuda K, Ohmura K, Minato N, Katsura Y, Kawamoto H. T/NK bipotent progenitors in the thymus retain the potential to generate dendritic cells. J Immunol 2003; 171:3401-3406.
-
(2003)
J Immunol
, vol.171
, pp. 3401-3406
-
-
Shen, H.Q.1
Lu, M.2
Ikawa, T.3
Masuda, K.4
Ohmura, K.5
Minato, N.6
Katsura, Y.7
Kawamoto, H.8
-
60
-
-
0027205082
-
Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population
-
Ardavin C, Wu L, Li CL, Shortman K. Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population. Nature 1993; 362:761-763.
-
(1993)
Nature
, vol.362
, pp. 761-763
-
-
Ardavin, C.1
Wu, L.2
Li, C.L.3
Shortman, K.4
-
61
-
-
0033119330
-
Pleiotropic changes controlled by the pre-T-cell receptor
-
von Boehmer H, Aifantis I, Feinberg J, Lechner O, Saint-Ruf C, Walter U, Buer J, Azogui O. Pleiotropic changes controlled by the pre-T-cell receptor. Curr Opin Immunol 1999; 11:135-142.
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 135-142
-
-
Von Boehmer, H.1
Aifantis, I.2
Feinberg, J.3
Lechner, O.4
Saint-Ruf, C.5
Walter, U.6
Buer, J.7
Azogui, O.8
-
62
-
-
0034509457
-
Branching out to gain control: How the pre-TCR is linked to multiple functions
-
Kruisbeek AM, Haks MC, Carleton M, Michie AM, Zúñiga- Pflücker JC, Wiest DL. Branching out to gain control: how the pre-TCR is linked to multiple functions. Immunol Today 2000; 21:637-644.
-
(2000)
Immunol Today
, vol.21
, pp. 637-644
-
-
Kruisbeek, A.M.1
Haks, M.C.2
Carleton, M.3
Michie, A.M.4
Zúñiga- Pflücker, J.C.5
Wiest, D.L.6
-
63
-
-
0036776370
-
Regulation of thymocyte differentiation: Pre-TCR signals and beta-selection
-
Michie AM, Zuniga-Pflucker JC. Regulation of thymocyte differentiation: pre-TCR signals and beta-selection. Semin Immunol 2002; 14:311-323.
-
(2002)
Semin Immunol
, vol.14
, pp. 311-323
-
-
Michie, A.M.1
Zuniga-Pflucker, J.C.2
-
64
-
-
0026585781
-
RAG-1-deficient mice have no mature B and T lymphocytes
-
Mombaerts P, Iacomini J, Johnson RS, Herrup K, Tonegawa S, Papaioannou VE. RAG-1-deficient mice have no mature B and T lymphocytes. Cell 1992; 68: 869-877.
-
(1992)
Cell
, vol.68
, pp. 869-877
-
-
Mombaerts, P.1
Iacomini, J.2
Johnson, R.S.3
Herrup, K.4
Tonegawa, S.5
Papaioannou, V.E.6
-
65
-
-
0026581936
-
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
-
Shinkai Y, Rathbun G, Lam K-P, Oltz EM, Stewart V, Mendelsohn M, Charron J, Datta M, Young F, Stall AM, Alt FW. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 1992; 68:855-867.
-
(1992)
Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.-P.3
Oltz, E.M.4
Stewart, V.5
Mendelsohn, M.6
Charron, J.7
Datta, M.8
Young, F.9
Stall, A.M.10
Alt, F.W.11
-
66
-
-
0029065488
-
Crucial role of the pre-T-cell receptor alpha gene in development of alpha beta but not gamma delta T cells
-
Fehling HJ, Krotkova A, Saint-Ruf C, von Boehmer H. Crucial role of the pre-T-cell receptor alpha gene in development of alpha beta but not gamma delta T cells. Nature 1995; 375:795-798.
-
(1995)
Nature
, vol.375
, pp. 795-798
-
-
Fehling, H.J.1
Krotkova, A.2
Saint-Ruf, C.3
Von Boehmer, H.4
-
67
-
-
0026522204
-
Profound block in thymocyte development in mice lacking p56lck
-
Molina TJ, Kishihara K, Siderovski DP, van Ewijk W, Narendran A, Timms E, Wakeham A, Paige CJ, Hartmann KU, Veillette A, Davidson D, Mak TW. Profound block in thymocyte development in mice lacking p56lck. Nature 1992; 357:161-164.
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
Kishihara, K.2
Siderovski, D.P.3
Van Ewijk, W.4
Narendran, A.5
Timms, E.6
Wakeham, A.7
Paige, C.J.8
Hartmann, K.U.9
Veillette, A.10
Davidson, D.11
Mak, T.W.12
-
68
-
-
0030886836
-
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
-
Cheng AM, Negishi I, Anderson SJ, Chan AC, Bolen J, Loh DY, Pawson T. The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. Proc Natl Acad Sci U S A 1997; 94:9797-9801.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 9797-9801
-
-
Cheng, A.M.1
Negishi, I.2
Anderson, S.J.3
Chan, A.C.4
Bolen, J.5
Loh, D.Y.6
Pawson, T.7
-
69
-
-
0033103833
-
Essential role of LAT in T cell development
-
Zhang W, Sommers CL, Burshtyn DN, Stebbins CC, Dejarnette JB, Trible RP, Grinberg A, Tsay HC, Jacobs HM, Kessler CM, Long EO, Love PE, Samelson LE. Essential role of LAT in T cell development. Immunity 1999; 10:323-332.
-
(1999)
Immunity
, vol.10
, pp. 323-332
-
-
Zhang, W.1
Sommers, C.L.2
Burshtyn, D.N.3
Stebbins, C.C.4
Dejarnette, J.B.5
Trible, R.P.6
Grinberg, A.7
Tsay, H.C.8
Jacobs, H.M.9
Kessler, C.M.10
Long, E.O.11
Love, P.E.12
Samelson, L.E.13
-
70
-
-
0032563256
-
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
-
Pivniouk V, Tsitsikov E, Swinton P, Rathbun G, Alt FW, Geha RS. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell 1998; 94:229-238.
-
(1998)
Cell
, vol.94
, pp. 229-238
-
-
Pivniouk, V.1
Tsitsikov, E.2
Swinton, P.3
Rathbun, G.4
Alt, F.W.5
Geha, R.S.6
-
71
-
-
0033179243
-
Signals involved in gamma/delta T cell versus alpha/ beta T cell lineage commitment
-
Hayday AC, Barber DF, Douglas N, Hoffman ES. Signals involved in gamma/delta T cell versus alpha/ beta T cell lineage commitment. Semin Immunol 1999; 11:239-249.
-
(1999)
Semin Immunol
, vol.11
, pp. 239-249
-
-
Hayday, A.C.1
Barber, D.F.2
Douglas, N.3
Hoffman, E.S.4
-
72
-
-
0035314009
-
T cell fate specification and alphabeta/gammadelta lineage commitment
-
MacDonald HR, Radtke F, Wilson A. T cell fate specification and alphabeta/gammadelta lineage commitment. Curr Opin Immunol 2001; 13:219-224.
-
(2001)
Curr Opin Immunol
, vol.13
, pp. 219-224
-
-
MacDonald, H.R.1
Radtke, F.2
Wilson, A.3
-
73
-
-
0025607947
-
Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro
-
Petrie HT, Hugo P, Scollay R, Shortman K. Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro. J Exp Med 1990; 172:1583-1588.
-
(1990)
J Exp Med
, vol.172
, pp. 1583-1588
-
-
Petrie, H.T.1
Hugo, P.2
Scollay, R.3
Shortman, K.4
-
74
-
-
0033009891
-
Selection of the T cell repertoire
-
Sebzda E, Mariathasan S, Ohteki T, Jones R, Bachmann MF, Ohashi PS. Selection of the T cell repertoire. Annu Rev Immunol 1999; 17:829-874.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 829-874
-
-
Sebzda, E.1
Mariathasan, S.2
Ohteki, T.3
Jones, R.4
Bachmann, M.F.5
Ohashi, P.S.6
-
75
-
-
0026721377
-
Exclusion and inclusion of alpha and beta T cell receptor alleles
-
Borgulya P, Kishi H, Uematsu Y, von Boehmer H. Exclusion and inclusion of alpha and beta T cell receptor alleles. Cell 1992; 69:529-537.
-
(1992)
Cell
, vol.69
, pp. 529-537
-
-
Borgulya, P.1
Kishi, H.2
Uematsu, Y.3
Von Boehmer, H.4
-
76
-
-
0026661878
-
Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression
-
Brandie D, Muller C, Rulicke T, Hengartner H, Pircher H. Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression. Proc Natl Acad Sci U S A 1992; 89:9529-9533.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 9529-9533
-
-
Brandie, D.1
Muller, C.2
Rulicke, T.3
Hengartner, H.4
Pircher, H.5
-
77
-
-
0035920573
-
The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo
-
Yannoutsos N, Wilson P, Yu W, Chen HT, Nussenzweig A, Petrie H, Nussenzweig MC. The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo. J Exp Med 2001; 194:471-480.
-
(2001)
J Exp Med
, vol.194
, pp. 471-480
-
-
Yannoutsos, N.1
Wilson, P.2
Yu, W.3
Chen, H.T.4
Nussenzweig, A.5
Petrie, H.6
Nussenzweig, M.C.7
-
78
-
-
0025933951
-
Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
-
Huesmann M, Scott B, Kisielow P, von Boehmer H. Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 1991; 66:533-540.
-
(1991)
Cell
, vol.66
, pp. 533-540
-
-
Huesmann, M.1
Scott, B.2
Kisielow, P.3
Von Boehmer, H.4
-
79
-
-
0028054017
-
T-cell apoptosis detected in situ during positive and negative selection in the thymus
-
Surh CD, Sprent J. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 1994; 372:100-103.
-
(1994)
Nature
, vol.372
, pp. 100-103
-
-
Surh, C.D.1
Sprent, J.2
-
80
-
-
0035999828
-
Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes
-
Guo J, Hawwari A, Li H, Sun Z, Mahanta SK, Littman DR, Krangel MS, He YW. Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. Nat Immunol 2002; 3: 469-476.
-
(2002)
Nat Immunol
, vol.3
, pp. 469-476
-
-
Guo, J.1
Hawwari, A.2
Li, H.3
Sun, Z.4
Mahanta, S.K.5
Littman, D.R.6
Krangel, M.S.7
He, Y.W.8
-
81
-
-
0028273017
-
Evidence for a differential avidity model of T cell selection in the thymus
-
Ashton-Rickardt PG, Bandeira A, Delaney JR, Van Kaer L, Pircher HP, Zinkernagel RM, Tonegawa S. Evidence for a differential avidity model of T cell selection in the thymus. Cell 1994; 76:651-663.
-
(1994)
Cell
, vol.76
, pp. 651-663
-
-
Ashton-Rickardt, P.G.1
Bandeira, A.2
Delaney, J.R.3
Van Kaer, L.4
Pircher, H.P.5
Zinkernagel, R.M.6
Tonegawa, S.7
-
82
-
-
0028178784
-
T cell receptor antagonist peptides induce positive selection
-
Hogquist KA, Jameson SC, Heath WR, Howard JL, Bevan MJ, Carbone FR. T cell receptor antagonist peptides induce positive selection. Cell 1994; 76:17-27.
-
(1994)
Cell
, vol.76
, pp. 17-27
-
-
Hogquist, K.A.1
Jameson, S.C.2
Heath, W.R.3
Howard, J.L.4
Bevan, M.J.5
Carbone, F.R.6
-
83
-
-
0023663430
-
T cell tolerance by clonal elimination in the thymus
-
Kappler JW, Roehm N, Marrack P. T cell tolerance by clonal elimination in the thymus. Cell 1987; 49: 273-280.
-
(1987)
Cell
, vol.49
, pp. 273-280
-
-
Kappler, J.W.1
Roehm, N.2
Marrack, P.3
-
84
-
-
0037084784
-
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
-
Ramsey C, Winqvist O, Puhakka L, Halonen M, Moro A, Kampe O, Eskelin P, Pelto-Huikko M, Peltonen L. Aire deficient mice develop multiple features of APECED phenotype and show altered immune response. Hum Mol Genet 2002; 11:397-409.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 397-409
-
-
Ramsey, C.1
Winqvist, O.2
Puhakka, L.3
Halonen, M.4
Moro, A.5
Kampe, O.6
Eskelin, P.7
Pelto-Huikko, M.8
Peltonen, L.9
-
85
-
-
0034732334
-
The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate
-
Yasutomo K, Doyle C, Miele L, Fuchs C, Germain RN. The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate. Nature 2000; 404:506-510.
-
(2000)
Nature
, vol.404
, pp. 506-510
-
-
Yasutomo, K.1
Doyle, C.2
Miele, L.3
Fuchs, C.4
Germain, R.N.5
-
86
-
-
1542377327
-
Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo
-
Liu X, Bosselut R. Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. Nat Immunol 2004; 5:280-288.
-
(2004)
Nat Immunol
, vol.5
, pp. 280-288
-
-
Liu, X.1
Bosselut, R.2
-
88
-
-
0033696599
-
Coreceptor reversal in the thymus: Signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells
-
Brugnera E, Bhandoola A, Cibotti R, Yu Q, Guinter TI, Yamashita Y, Sharrow SO, Singer A. Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells. Immunity 2000; 13: 59-71.
-
(2000)
Immunity
, vol.13
, pp. 59-71
-
-
Brugnera, E.1
Bhandoola, A.2
Cibotti, R.3
Yu, Q.4
Guinter, T.I.5
Yamashita, Y.6
Sharrow, S.O.7
Singer, A.8
-
89
-
-
0028988659
-
Thymic emigration: Conveyor belts or lucky dips?
-
discussion 273-274
-
Scollay R, Godfrey DI. Thymic emigration: conveyor belts or lucky dips? Immunol Today 1995; 16:268-273; discussion 273-274.
-
(1995)
Immunol Today
, vol.16
, pp. 268-273
-
-
Scollay, R.1
Godfrey, D.I.2
-
90
-
-
9144228777
-
Continued maturation of thymic emigrants in the periphery
-
Boursalian TE, Golob J, Soper DM, Cooper CJ, Fink PJ. Continued maturation of thymic emigrants in the periphery. Nat Immunol 2004; 5:418-425.
-
(2004)
Nat Immunol
, vol.5
, pp. 418-425
-
-
Boursalian, T.E.1
Golob, J.2
Soper, D.M.3
Cooper, C.J.4
Fink, P.J.5
-
91
-
-
9144259224
-
The fourth way? Harnessing aggressive tendencies in the thymus
-
Baldwin TA, Hogquist KA, Jameson SC. The fourth way? Harnessing aggressive tendencies in the thymus. J Immunol 2004; 173:6515-6520.
-
(2004)
J Immunol
, vol.173
, pp. 6515-6520
-
-
Baldwin, T.A.1
Hogquist, K.A.2
Jameson, S.C.3
-
93
-
-
0242668752
-
A role of CXC chemokine ligand 12/stromal cell-derived factor-1/pre-B cell growth stimulating factor and its receptor CXCR4 in fetal and adult T cell development in vivo
-
Ara T, Itoi M, Kawabata K, Egawa T, Tokoyoda K, Sugiyama T, Fujii N, Amagai T, Nagasawa T. A role of CXC chemokine ligand 12/stromal cell-derived factor-1/pre-B cell growth stimulating factor and its receptor CXCR4 in fetal and adult T cell development in vivo. J Immunol 2003; 170:4649-4655.
-
(2003)
J Immunol
, vol.170
, pp. 4649-4655
-
-
Ara, T.1
Itoi, M.2
Kawabata, K.3
Egawa, T.4
Tokoyoda, K.5
Sugiyama, T.6
Fujii, N.7
Amagai, T.8
Nagasawa, T.9
-
94
-
-
0142149043
-
Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus
-
Plotkin J, Prockop SE, Lepique A, Petrie HT. Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the postnatal thymus. J Immunol 2003; 171:4521-4527.
-
(2003)
J Immunol
, vol.171
, pp. 4521-4527
-
-
Plotkin, J.1
Prockop, S.E.2
Lepique, A.3
Petrie, H.T.4
-
95
-
-
4344574151
-
Thymic T cell development and progenitor localization depend on CCR7
-
Misslitz A, Pabst O, Hintzen G, Ohl L, Kremmer E, Petrie HT, Forster R. Thymic T cell development and progenitor localization depend on CCR7. J Exp Med 2004; 200:481-491.
-
(2004)
J Exp Med
, vol.200
, pp. 481-491
-
-
Misslitz, A.1
Pabst, O.2
Hintzen, G.3
Ohl, L.4
Kremmer, E.5
Petrie, H.T.6
Forster, R.7
-
96
-
-
10944269361
-
Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development
-
Benz C, Heinzel K, Bleul CC. Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development. Eur J Immunol 2004; 34:3652-3663.
-
(2004)
Eur J Immunol
, vol.34
, pp. 3652-3663
-
-
Benz, C.1
Heinzel, K.2
Bleul, C.C.3
-
97
-
-
0242636376
-
Cell migration and the control of postnatal T-cell lymphopoiesis in the thymus
-
Petrie HT. Cell migration and the control of postnatal T-cell lymphopoiesis in the thymus. Nat Rev Immunol 2003; 3:859-866.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 859-866
-
-
Petrie, H.T.1
-
98
-
-
0037108384
-
Stromal cells provide the matrix for migration of early lymphoid progenitors through the thymic cortex
-
Prockop SE, Palencia S, Ryan CM, Gordon K, Gray D, Petrie HT. Stromal cells provide the matrix for migration of early lymphoid progenitors through the thymic cortex. J Immunol 2002; 169:4354-4361.
-
(2002)
J Immunol
, vol.169
, pp. 4354-4361
-
-
Prockop, S.E.1
Palencia, S.2
Ryan, C.M.3
Gordon, K.4
Gray, D.5
Petrie, H.T.6
-
99
-
-
4344668118
-
CCR7 signals are essential for cortex-medulla migration of developing thymocytes
-
Ueno T, Saito F, Gray DH, Kuse S, Hieshima K, Nakano H, Kakiuchi T, Lipp M, Boyd RL, Takahama Y. CCR7 signals are essential for cortex-medulla migration of developing thymocytes. J Exp Med 2004; 200:493-505.
-
(2004)
J Exp Med
, vol.200
, pp. 493-505
-
-
Ueno, T.1
Saito, F.2
Gray, D.H.3
Kuse, S.4
Hieshima, K.5
Nakano, H.6
Kakiuchi, T.7
Lipp, M.8
Boyd, R.L.9
Takahama, Y.10
-
100
-
-
0034650922
-
Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling
-
Norment AM, Bogatzki LY, Gantner BN, Bevan MJ. Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. J Immunol 2000; 164:639-648.
-
(2000)
J Immunol
, vol.164
, pp. 639-648
-
-
Norment, A.M.1
Bogatzki, L.Y.2
Gantner, B.N.3
Bevan, M.J.4
-
101
-
-
0036136878
-
Characterization of CCR9 expression and CCL25/thymus-expressed chemokine responsiveness during T cell development: CD3(high)CD69+ thymocytes and gammadeltaTCR+ thymocytes preferentially respond to CCL25
-
Uehara S, Song K, Farber JM, Love PE. Characterization of CCR9 expression and CCL25/thymus-expressed chemokine responsiveness during T cell development: CD3(high)CD69+ thymocytes and gammadeltaTCR+ thymocytes preferentially respond to CCL25. J Immunol 2002; 168:134-142.
-
(2002)
J Immunol
, vol.168
, pp. 134-142
-
-
Uehara, S.1
Song, K.2
Farber, J.M.3
Love, P.E.4
-
102
-
-
18344385280
-
Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus
-
Ueno T, Hara K, Willis MS, Malin MA, Hopken UE, Gray DH, Matsushima K, Lipp M, Springer TA, Boyd RL, Yoshie O, Takahama Y. Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus. Immunity 2002; 16:205-218.
-
(2002)
Immunity
, vol.16
, pp. 205-218
-
-
Ueno, T.1
Hara, K.2
Willis, M.S.3
Malin, M.A.4
Hopken, U.E.5
Gray, D.H.6
Matsushima, K.7
Lipp, M.8
Springer, T.A.9
Boyd, R.L.10
Yoshie, O.11
Takahama, Y.12
-
103
-
-
1642289268
-
CCR7 directs the migration of thymocytes into the thymic medulla
-
Kwan J, Killeen N. CCR7 directs the migration of thymocytes into the thymic medulla. J Immunol 2004; 172:3999-4007.
-
(2004)
J Immunol
, vol.172
, pp. 3999-4007
-
-
Kwan, J.1
Killeen, N.2
-
104
-
-
0029831978
-
Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development
-
Sun L, Liu A, Georgopoulos K. Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development. EMBO J 1996; 15:5358-5369.
-
(1996)
EMBO J
, vol.15
, pp. 5358-5369
-
-
Sun, L.1
Liu, A.2
Georgopoulos, K.3
-
105
-
-
0028001362
-
The Ikaros gene is required for the development of all lymphoid lineages
-
Georgopoulos K, Bigby M, Wang JH, Molnar A, Wu P, Winandy S, Sharpe A. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994; 79:143-156.
-
(1994)
Cell
, vol.79
, pp. 143-156
-
-
Georgopoulos, K.1
Bigby, M.2
Wang, J.H.3
Molnar, A.4
Wu, P.5
Winandy, S.6
Sharpe, A.7
-
106
-
-
0029828994
-
Transcription factor GATA-3 is required for development of the T-cell lineage
-
Ting CN, Olson MC, Barton KP, Leiden JM. Transcription factor GATA-3 is required for development of the T-cell lineage. Nature 1996; 384:474-478.
-
(1996)
Nature
, vol.384
, pp. 474-478
-
-
Ting, C.N.1
Olson, M.C.2
Barton, K.P.3
Leiden, J.M.4
-
108
-
-
0028136726
-
Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages
-
Scott EW, Simon MC, Anastasi J, Singh H. Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 1994; 265:1573-1577.
-
(1994)
Science
, vol.265
, pp. 1573-1577
-
-
Scott, E.W.1
Simon, M.C.2
Anastasi, J.3
Singh, H.4
-
109
-
-
0038106526
-
Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor
-
Papathanasiou P, Perkins AC, Cobb BS, Ferrini R, Sridharan R, Hoyne GF, Nelms KA, Smale ST, Goodnow CC. Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity 2003; 19:131-144.
-
(2003)
Immunity
, vol.19
, pp. 131-144
-
-
Papathanasiou, P.1
Perkins, A.C.2
Cobb, B.S.3
Ferrini, R.4
Sridharan, R.5
Hoyne, G.F.6
Nelms, K.A.7
Smale, S.T.8
Goodnow, C.C.9
-
110
-
-
0030498975
-
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
-
Wang JH, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, Bigby M, Georgopoulos K. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996; 5:537-549.
-
(1996)
Immunity
, vol.5
, pp. 537-549
-
-
Wang, J.H.1
Nichogiannopoulou, A.2
Wu, L.3
Sun, L.4
Sharpe, A.H.5
Bigby, M.6
Georgopoulos, K.7
-
111
-
-
0034970328
-
Identification of committed NK cell progenitors in adult murine bone marrow
-
Rosmaraki EE, Douagi I, Roth C, Colucci F, Cumano A, Di Santo JP. Identification of committed NK cell progenitors in adult murine bone marrow. Eur J Immunol 2001; 31:1900-1909.
-
(2001)
Eur J Immunol
, vol.31
, pp. 1900-1909
-
-
Rosmaraki, E.E.1
Douagi, I.2
Roth, C.3
Colucci, F.4
Cumano, A.5
Di Santo, J.P.6
-
112
-
-
0036607528
-
Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3
-
Anderson MK, Hernandez-Hoyos G, Dionne CJ, Arias AM, Chen D, Rothenberg EV. Definition of regulatory network elements for T cell development by perturbation analysis with PU.1 and GATA-3. Dev Biol 2002; 246:103-121.
-
(2002)
Dev Biol
, vol.246
, pp. 103-121
-
-
Anderson, M.K.1
Hernandez-Hoyos, G.2
Dionne, C.J.3
Arias, A.M.4
Chen, D.5
Rothenberg, E.V.6
-
113
-
-
0034717335
-
Regulation of B lymphocyte and macrophage development by graded expression of PU.1
-
DeKoter RP, Singh H. Regulation of B lymphocyte and macrophage development by graded expression of PU.1. Science 2000; 288:1439-1441.
-
(2000)
Science
, vol.288
, pp. 1439-1441
-
-
DeKoter, R.P.1
Singh, H.2
-
114
-
-
0036199657
-
PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors
-
DeKoter RP, Lee HJ, Singh H. PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors. Immunity 2002; 16:297-309.
-
(2002)
Immunity
, vol.16
, pp. 297-309
-
-
DeKoter, R.P.1
Lee, H.J.2
Singh, H.3
-
115
-
-
5444249783
-
GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells
-
Xue HH, Bollenbacher J, Rovella V, Tripuraneni R, Du YB, Liu CY, Williams A, McCoy JP, Leonard WJ. GA binding protein regulates interleukin 7 receptor alpha-chain gene expression in T cells. Nat Immunol 2004; 5:1036-1044.
-
(2004)
Nat Immunol
, vol.5
, pp. 1036-1044
-
-
Xue, H.H.1
Bollenbacher, J.2
Rovella, V.3
Tripuraneni, R.4
Du, Y.B.5
Liu, C.Y.6
Williams, A.7
McCoy, J.P.8
Leonard, W.J.9
-
116
-
-
0033551402
-
The myb gene family in cell growth, differentiation and apoptosis
-
Oh IH, Reddy EP. The myb gene family in cell growth, differentiation and apoptosis. Oncogene 1999; 18:3017-3033.
-
(1999)
Oncogene
, vol.18
, pp. 3017-3033
-
-
Oh, I.H.1
Reddy, E.P.2
-
117
-
-
0025821494
-
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
-
Mucenski ML, McLain K, Kier AB, Swerdlow SH, Schreiner CM, Miller TA, Pietryga DW, Scott WJ Jr., Potter SS. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 1991; 65:677-689.
-
(1991)
Cell
, vol.65
, pp. 677-689
-
-
Mucenski, M.L.1
McLain, K.2
Kier, A.B.3
Swerdlow, S.H.4
Schreiner, C.M.5
Miller, T.A.6
Pietryga, D.W.7
Scott Jr., W.J.8
Potter, S.S.9
-
118
-
-
3242784226
-
Critical functions for c-Myb at three checkpoints during thymocyte development
-
Bender TP, Kremer CS, Kraus M, Buch T, Rajewsky K. Critical functions for c-Myb at three checkpoints during thymocyte development. Nat Immunol 2004; 5:721-729.
-
(2004)
Nat Immunol
, vol.5
, pp. 721-729
-
-
Bender, T.P.1
Kremer, C.S.2
Kraus, M.3
Buch, T.4
Rajewsky, K.5
-
119
-
-
6944227821
-
Requirement of c-myb in T cell development and in mature T cell function
-
Lieu YK, Kumar A, Pajerowski AG, Rogers TJ, Reddy EP. Requirement of c-myb in T cell development and in mature T cell function. Proc Natl Acad Sci USA 2004; 101:14853-14858.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14853-14858
-
-
Lieu, Y.K.1
Kumar, A.2
Pajerowski, A.G.3
Rogers, T.J.4
Reddy, E.P.5
-
120
-
-
0033579803
-
Positive and negative regulation of V(D)J recombination by the E2A proteins
-
Bain G, Romanow WJ, Albers K, Havran WL, Murre C. Positive and negative regulation of V(D)J recombination by the E2A proteins. J Exp Med 1999; 189:289-300.
-
(1999)
J Exp Med
, vol.189
, pp. 289-300
-
-
Bain, G.1
Romanow, W.J.2
Albers, K.3
Havran, W.L.4
Murre, C.5
-
121
-
-
0033811622
-
Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB
-
Barndt RJ, Dai M, Zhuang Y. Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB. Mol Cell Biol 2000; 20:6677-6685.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6677-6685
-
-
Barndt, R.J.1
Dai, M.2
Zhuang, Y.3
-
122
-
-
0026045243
-
Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line
-
Schlissel M, Voronova A, Baltimore D. Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line. Genes Dev 1991; 5:1367-1376.
-
(1991)
Genes Dev
, vol.5
, pp. 1367-1376
-
-
Schlissel, M.1
Voronova, A.2
Baltimore, D.3
-
123
-
-
0034252945
-
SCL and LMO1 alter thymocyte differentiation: Inhibition of E2A-HEB function and pre-T alpha chain expression
-
Herblot S, Steff AM, Hugo P, Aplan PD, Hoang T. SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression. Nat Immunol 2000; 1:138-144.
-
(2000)
Nat Immunol
, vol.1
, pp. 138-144
-
-
Herblot, S.1
Steff, A.M.2
Hugo, P.3
Aplan, P.D.4
Hoang, T.5
-
124
-
-
0035881544
-
E2A and HEB activate the pre-TCR alpha promoter during immature T cell development
-
Takeuchi A, Yamasaki S, Takase K, Nakatsu F, Arase H, Onodera M, Saito T. E2A and HEB activate the pre-TCR alpha promoter during immature T cell development. J Immunol 2001; 167:2157-2163.
-
(2001)
J Immunol
, vol.167
, pp. 2157-2163
-
-
Takeuchi, A.1
Yamasaki, S.2
Takase, K.3
Nakatsu, F.4
Arase, H.5
Onodera, M.6
Saito, T.7
-
125
-
-
0035477620
-
The upstream enhancer is necessary and sufficient for the expression of the pre-T cell receptor alpha gene in immature T lymphocytes
-
Reizis B, Leder P. The upstream enhancer is necessary and sufficient for the expression of the pre-T cell receptor alpha gene in immature T lymphocytes. J Exp Med 2001; 194:979-990.
-
(2001)
J Exp Med
, vol.194
, pp. 979-990
-
-
Reizis, B.1
Leder, P.2
-
126
-
-
0027237711
-
A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines
-
Sawada S, Littman DR. A heterodimer of HEB and an E12-related protein interacts with the CD4 enhancer and regulates its activity in T-cell lines. Mol Cell Biol 1993; 13:5620-5628.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 5620-5628
-
-
Sawada, S.1
Littman, D.R.2
-
127
-
-
0033506485
-
Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice
-
Kim D, Peng XC, Sun XH. Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice. Mol Cell Biol 1999; 19:8240-8253.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 8240-8253
-
-
Kim, D.1
Peng, X.C.2
Sun, X.H.3
-
128
-
-
0032764978
-
Overexpression of the helix-loop-helix protein Id2 blocks T cell development at multiple stages
-
Morrow MA, Mayer EW, Perez CA, Adlam M, Siu G. Overexpression of the helix-loop-helix protein Id2 blocks T cell development at multiple stages. Mol Immunol 1999; 36:491-503.
-
(1999)
Mol Immunol
, vol.36
, pp. 491-503
-
-
Morrow, M.A.1
Mayer, E.W.2
Perez, C.A.3
Adlam, M.4
Siu, G.5
-
129
-
-
0033577695
-
Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors
-
Blom B, Heemskerk MH, Verschuren MC, van Dongen JJ, Stegmann AP, Bakker AQ, Couwenberg F, Res PC, Spits H. Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors. EMBO J 1999; 18: 2793-2802.
-
(1999)
EMBO J
, vol.18
, pp. 2793-2802
-
-
Blom, B.1
Heemskerk, M.H.2
Verschuren, M.C.3
Van Dongen, J.J.4
Stegmann, A.P.5
Bakker, A.Q.6
Couwenberg, F.7
Res, P.C.8
Spits, H.9
-
130
-
-
0030665673
-
Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3
-
Heemskerk MH, Blom B, Nolan G, Stegmann AP, Bakker AQ, Weijer K, Res PC, Spits H. Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J Exp Med 1997; 186:1597-1602.
-
(1997)
J Exp Med
, vol.186
, pp. 1597-1602
-
-
Heemskerk, M.H.1
Blom, B.2
Nolan, G.3
Stegmann, A.P.4
Bakker, A.Q.5
Weijer, K.6
Res, P.C.7
Spits, H.8
-
131
-
-
0033602163
-
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2
-
Yokota Y, Mansouri A, Mori S, Sugawara S, Adachi S, Nishikawa S, Gruss P. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 1999; 397:702-706.
-
(1999)
Nature
, vol.397
, pp. 702-706
-
-
Yokota, Y.1
Mansouri, A.2
Mori, S.3
Sugawara, S.4
Adachi, S.5
Nishikawa, S.6
Gruss, P.7
-
132
-
-
0035942179
-
Commitment to natural killer cells requires the helix-loop-helix inhibitor Id2
-
Ikawa T, Fujimoto S, Kawamoto H, Katsura Y, Yokota Y. Commitment to natural killer cells requires the helix-loop-helix inhibitor Id2. Proc Natl Acad Sci U S A 2001; 98:5164-5169.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5164-5169
-
-
Ikawa, T.1
Fujimoto, S.2
Kawamoto, H.3
Katsura, Y.4
Yokota, Y.5
-
133
-
-
0035260791
-
Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade
-
Bain G, Cravatt CB, Loomans C, Alberola-Ila J, Hedrick SM, Murre C. Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade. Nat Immunol 2001; 2:165-171.
-
(2001)
Nat Immunol
, vol.2
, pp. 165-171
-
-
Bain, G.1
Cravatt, C.B.2
Loomans, C.3
Alberola-Ila, J.4
Hedrick, S.M.5
Murre, C.6
-
134
-
-
0035903286
-
Early thymocyte development is regulated by modulation of E2A protein activity
-
Engel I, Johns C, Bain G, Rivera RR, Murre C. Early thymocyte development is regulated by modulation of E2A protein activity. J Exp Med 2001; 194: 733-745.
-
(2001)
J Exp Med
, vol.194
, pp. 733-745
-
-
Engel, I.1
Johns, C.2
Bain, G.3
Rivera, R.R.4
Murre, C.5
-
135
-
-
0842285394
-
E2A proteins enforce a proliferation checkpoint in developing thymocytes
-
Engel I, Murre C. E2A proteins enforce a proliferation checkpoint in developing thymocytes. EMBO J 2004; 23:202-211.
-
(2004)
EMBO J
, vol.23
, pp. 202-211
-
-
Engel, I.1
Murre, C.2
-
136
-
-
0033405692
-
Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47
-
Bain G, Quong MW, Soloff RS, Hedrick SM, Murre C. Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47. J Exp Med 1999; 190:1605-1616.
-
(1999)
J Exp Med
, vol.190
, pp. 1605-1616
-
-
Bain, G.1
Quong, M.W.2
Soloff, R.S.3
Hedrick, S.M.4
Murre, C.5
-
137
-
-
0033984819
-
Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3
-
Rivera RR, Johns CP, Quan J, Johnson RS, Murre C. Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. Immunity 2000; 12:17-26.
-
(2000)
Immunity
, vol.12
, pp. 17-26
-
-
Rivera, R.R.1
Johns, C.P.2
Quan, J.3
Johnson, R.S.4
Murre, C.5
-
138
-
-
0029051162
-
Cytokine production and requirements during T-cell development
-
Zlotnik A, Moore TA. Cytokine production and requirements during T-cell development. Curr Opin Immunol 1995; 7:206-213.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 206-213
-
-
Zlotnik, A.1
Moore, T.A.2
-
139
-
-
0019781170
-
Thymus in mice bearing the Steel mutation. Morphologic studies on fetal, neonatal, organ-cultured, and grafted fetal thymus
-
Asamoto H, Mandel TE. Thymus in mice bearing the Steel mutation. Morphologic studies on fetal, neonatal, organ-cultured, and grafted fetal thymus. Lab Invest 1981; 45:418-426.
-
(1981)
Lab Invest
, vol.45
, pp. 418-426
-
-
Asamoto, H.1
Mandel, T.E.2
-
140
-
-
0026670892
-
Phenotypic and functional characterization of c-kit expression during intrathymic T cell development
-
Godfrey DI, Zlotnik A, Suda T. Phenotypic and functional characterization of c-kit expression during intrathymic T cell development. J Immunol 1992; 149:2281-2285.
-
(1992)
J Immunol
, vol.149
, pp. 2281-2285
-
-
Godfrey, D.I.1
Zlotnik, A.2
Suda, T.3
-
141
-
-
0028929565
-
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
-
von Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SE, Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 1995; 181: 1519-1526.
-
(1995)
J Exp Med
, vol.181
, pp. 1519-1526
-
-
Freeden-Jeffry, U.1
Vieira, P.2
Lucian, L.A.3
McNeil, T.4
Burdach, S.E.5
Murray, R.6
-
142
-
-
0031956471
-
In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development
-
Di Santo JP, Rodewald HR. In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development. Curr Opin Immunol 1998; 10: 196-207.
-
(1998)
Curr Opin Immunol
, vol.10
, pp. 196-207
-
-
Di Santo, J.P.1
Rodewald, H.R.2
-
143
-
-
0028804041
-
Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo
-
Rodewald HR, Kretzschmar K, Swat W, Takeda S. Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo. Immunity 1995; 3:313-319.
-
(1995)
Immunity
, vol.3
, pp. 313-319
-
-
Rodewald, H.R.1
Kretzschmar, K.2
Swat, W.3
Takeda, S.4
-
144
-
-
0027146421
-
Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells
-
Lyman SD, James L, Vanden Bos T, de Vries P, Brasel K, Gliniak B, Hollingsworth LT, Picha KS, McKenna HJ, Splett RR, Fletcher FA, Maraskovsky E, Farrah T, Foxworthe D, Williams DE, Beckmann MP. Molecular cloning of a ligand for the flt3/flk-2 tyrosine kinase receptor: a proliferative factor for primitive hematopoietic cells. Cell 1993; 75:1157-1167.
-
(1993)
Cell
, vol.75
, pp. 1157-1167
-
-
Lyman, S.D.1
James, L.2
Vanden Bos, T.3
De Vries, P.4
Brasel, K.5
Gliniak, B.6
Hollingsworth, L.T.7
Picha, K.S.8
McKenna, H.J.9
Splett, R.R.10
Fletcher, F.A.11
Maraskovsky, E.12
Farrah, T.13
Foxworthe, D.14
De Williams15
Beckmann, M.P.16
-
145
-
-
0025770646
-
A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations
-
Matthews W, Jordan CT, Wiegand GW, Pardoll D, Lemischka IR. A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations. Cell 1991; 65:1143-1152.
-
(1991)
Cell
, vol.65
, pp. 1143-1152
-
-
Matthews, W.1
Jordan, C.T.2
Wiegand, G.W.3
Pardoll, D.4
Lemischka, I.R.5
-
146
-
-
0031132519
-
Differential effects of Flk-2/ Flt-3 ligand and stem cell factor on murine thymic progenitor cells
-
Moore TA, Zlotnik A. Differential effects of Flk-2/ Flt-3 ligand and stem cell factor on murine thymic progenitor cells. J Immunol 1997; 158:4187-4192.
-
(1997)
J Immunol
, vol.158
, pp. 4187-4192
-
-
Moore, T.A.1
Zlotnik, A.2
-
147
-
-
0029097145
-
Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors
-
Mackarehtschian K, Hardin JD, Moore KA, Boast S, Goff SP, Lemischka IR. Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors. Immunity 1995; 3:147-161.
-
(1995)
Immunity
, vol.3
, pp. 147-161
-
-
Mackarehtschian, K.1
Hardin, J.D.2
Moore, K.A.3
Boast, S.4
Goff, S.P.5
Lemischka, I.R.6
-
148
-
-
0034210658
-
Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells
-
McKenna HJ, Stocking KL, Miller RE, Brasel K, De Smedt T, Maraskovsky E, Maliszewski CR, Lynch DH, Smith J, Pulendran B, Roux ER, Teepe M, Lyman SD, Peschon JJ. Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells. Blood 2000; 95:3489-3497.
-
(2000)
Blood
, vol.95
, pp. 3489-3497
-
-
McKenna, H.J.1
Stocking, K.L.2
Miller, R.E.3
Brasel, K.4
De Smedt, T.5
Maraskovsky, E.6
Maliszewski, C.R.7
Lynch, D.H.8
Smith, J.9
Pulendran, B.10
Roux, E.R.11
Teepe, M.12
Lyman, S.D.13
Peschon, J.J.14
-
149
-
-
0036797682
-
Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool
-
Sitnicka E, Bryder D, Theilgaard-Monch K, Buza-Vidas N, Adolfsson J, Jacobsen SE. Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool. Immunity 2002; 17:463-472.
-
(2002)
Immunity
, vol.17
, pp. 463-472
-
-
Sitnicka, E.1
Bryder, D.2
Theilgaard-Monch, K.3
Buza-Vidas, N.4
Adolfsson, J.5
Jacobsen, S.E.6
-
150
-
-
0031587875
-
Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- Mice
-
Maraskovsky E, O'Reilly LA, Teepe M, Corcoran LM, Peschon JJ, Strasser A. Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice. Cell 1997; 89:1011-1019.
-
(1997)
Cell
, vol.89
, pp. 1011-1019
-
-
Maraskovsky, E.1
O'Reilly, L.A.2
Teepe, M.3
Corcoran, L.M.4
Peschon, J.J.5
Strasser, A.6
-
151
-
-
0030874326
-
The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression
-
von Freeden-Jeffry U, Solvason N, Howard M, Murray R. The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 1997; 7:147-154.
-
(1997)
Immunity
, vol.7
, pp. 147-154
-
-
Freeden-Jeffry, U.1
Solvason, N.2
Howard, M.3
Murray, R.4
-
152
-
-
0030587133
-
Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- Mice
-
Moore TA, von Freeden-Jeffry U, Murray R, Zlotnik A. Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice. J Immunol 1996; 157:2366-2373.
-
(1996)
J Immunol
, vol.157
, pp. 2366-2373
-
-
Moore, T.A.1
Von Freeden-Jeffry, U.2
Murray, R.3
Zlotnik, A.4
-
153
-
-
0029957040
-
Interleukin 7 receptor-deficient mice lack gammadelta T cells
-
Maki K, Sunaga S, Komagata Y, Kodaira Y, Mabuchi A, Karasuyama H, Yokomuro K, Miyazaki JI, Ikuta K. Interleukin 7 receptor-deficient mice lack gammadelta T cells. Proc Natl Acad Sci U S A 1996; 93:7172-7177.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 7172-7177
-
-
Maki, K.1
Sunaga, S.2
Komagata, Y.3
Kodaira, Y.4
Mabuchi, A.5
Karasuyama, H.6
Yokomuro, K.7
Miyazaki, J.I.8
Ikuta, K.9
-
154
-
-
0030726968
-
The common cytokine receptor gamma chain controls survival of gamma/delta T cells
-
Malissen M, Pereira P, Gerber DJ, Malissen B, DiSanto JP. The common cytokine receptor gamma chain controls survival of gamma/delta T cells. J Exp Med 1997; 186:1277-1285.
-
(1997)
J Exp Med
, vol.186
, pp. 1277-1285
-
-
Malissen, M.1
Pereira, P.2
Gerber, D.J.3
Malissen, B.4
Disanto, J.P.5
-
155
-
-
0030978529
-
Pro-thymocyte expansion by c-kit and the common cytokine receptor gamma chain is essential for repertoire formation
-
Rodewald HR, Ogawa M, Haller C, Waskow C, DiSanto JP. Pro-thymocyte expansion by c-kit and the common cytokine receptor gamma chain is essential for repertoire formation. Immunity 1997; 6: 265-272.
-
(1997)
Immunity
, vol.6
, pp. 265-272
-
-
Rodewald, H.R.1
Ogawa, M.2
Haller, C.3
Waskow, C.4
Disanto, J.P.5
-
156
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
-
Peschon JJ, Morrissey PJ, Grabstein KH, Ramsdell FJ, Maraskovsky E, Gliniak BC, Park LS, Ziegler SF, Williams DE, Ware CB. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 1994; 180:1955-1960.
-
(1994)
J Exp Med
, vol.180
, pp. 1955-1960
-
-
Peschon, J.J.1
Morrissey, P.J.2
Grabstein, K.H.3
Ramsdell, F.J.4
Maraskovsky, E.5
Gliniak, B.C.6
Park, L.S.7
Ziegler, S.F.8
De Williams9
Ware, C.B.10
-
157
-
-
1642321960
-
Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation
-
Van De Wiele CJ, Marino JH, Murray BW, Vo SS, Whetsell ME, Teague TK. Thymocytes between the beta-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation. J Immunol 2004; 172:4235-4244.
-
(2004)
J Immunol
, vol.172
, pp. 4235-4244
-
-
Van De Wiele, C.J.1
Marino, J.H.2
Murray, B.W.3
Vo, S.S.4
Whetsell, M.E.5
Teague, T.K.6
-
158
-
-
0031587826
-
Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice
-
Akashi K, Kondo M, von Freeden-Jeffry U, Murray R, Weissman IL. Bcl-2 rescues T lymphopoiesis in interleukin-7 receptor-deficient mice. Cell 1997; 89: 1033-1041.
-
(1997)
Cell
, vol.89
, pp. 1033-1041
-
-
Akashi, K.1
Kondo, M.2
Von Freeden-Jeffry, U.3
Murray, R.4
Weissman, I.L.5
-
159
-
-
0036849781
-
Bax deficiency partially corrects interleukin-7 receptor alpha deficiency
-
Khaled AR, Li WQ, Huang J, Fry TJ, Khaled AS, Mackall CL, Muegge K, Young HA, Durum SK. Bax deficiency partially corrects interleukin-7 receptor alpha deficiency. Immunity 2002; 17:561-573.
-
(2002)
Immunity
, vol.17
, pp. 561-573
-
-
Khaled, A.R.1
Li, W.Q.2
Huang, J.3
Fry, T.J.4
Khaled, A.S.5
Mackall, C.L.6
Muegge, K.7
Young, H.A.8
Durum, S.K.9
-
160
-
-
0033406781
-
Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH
-
Khaled AR, Kim K, Hofmeister R, Muegge K, Durum SK. Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH. Proc Natl Acad Sci U S A 1999; 96:14476-14481.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 14476-14481
-
-
Khaled, A.R.1
Kim, K.2
Hofmeister, R.3
Muegge, K.4
Durum, S.K.5
-
161
-
-
3142691373
-
Interleukin-7 inactivates the pro-apoptotic protein Bad promoting T cell survival
-
Li WQ, Jiang Q, Khaled AR, Keller JR, Durum SK. Interleukin-7 inactivates the pro-apoptotic protein Bad promoting T cell survival. J Biol Chem 2004; 279: 29160-29166.
-
(2004)
J Biol Chem
, vol.279
, pp. 29160-29166
-
-
Li, W.Q.1
Jiang, Q.2
Khaled, A.R.3
Keller, J.R.4
Durum, S.K.5
-
162
-
-
0037111391
-
Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation
-
Hager-Theodorides AL, Outram SV, Shah DK, Sacedon R, Shrimpton RE, Vicente A, Varas A, Crompton T. Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation. J Immunol 2002; 169:5496-5504.
-
(2002)
J Immunol
, vol.169
, pp. 5496-5504
-
-
Hager-Theodorides, A.L.1
Outram, S.V.2
Shah, D.K.3
Sacedon, R.4
Shrimpton, R.E.5
Vicente, A.6
Varas, A.7
Crompton, T.8
-
163
-
-
0345689338
-
BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis
-
Tsai PT, Lee RA, Wu H. BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis. Blood 2003; 102:3947-3953.
-
(2003)
Blood
, vol.102
, pp. 3947-3953
-
-
Tsai, P.T.1
Lee, R.A.2
Wu, H.3
-
164
-
-
0037099676
-
The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development
-
Graf D, Nethisinghe S, Palmer DB, Fisher AG, Merkenschlager M. The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development. J Exp Med 2002; 196:163-171.
-
(2002)
J Exp Med
, vol.196
, pp. 163-171
-
-
Graf, D.1
Nethisinghe, S.2
Palmer, D.B.3
Fisher, A.G.4
Merkenschlager, M.5
-
165
-
-
0032532301
-
Critical involvement of Tcf-1 in expansion of thymocytes
-
Schilham MW, Wilson A, Moerer P, Benaissa-Trouw BJ, Cumano A, Clevers HC. Critical involvement of Tcf-1 in expansion of thymocytes. J Immunol 1998; 161:3984-3991.
-
(1998)
J Immunol
, vol.161
, pp. 3984-3991
-
-
Schilham, M.W.1
Wilson, A.2
Moerer, P.3
Benaissa-Trouw, B.J.4
Cumano, A.5
Clevers, H.C.6
-
166
-
-
0035134933
-
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription
-
Staal FJ, Meeldijk J, Moerer P, Jay P, van de Weerdt BC, Vainio S, Nolan GP, Clevers H. Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. Eur J Immunol 2001; 31:285-293.
-
(2001)
Eur J Immunol
, vol.31
, pp. 285-293
-
-
Staal, F.J.1
Meeldijk, J.2
Moerer, P.3
Jay, P.4
Van De Weerdt, B.C.5
Vainio, S.6
Nolan, G.P.7
Clevers, H.8
-
167
-
-
0035554684
-
Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development
-
Gounari F, Aifantis I, Khazaie K, Hoeflinger S, Harada N, Taketo MM, von Boehmer H. Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development. Nat Immunol 2001; 2:863-869.
-
(2001)
Nat Immunol
, vol.2
, pp. 863-869
-
-
Gounari, F.1
Aifantis, I.2
Khazaie, K.3
Hoeflinger, S.4
Harada, N.5
Taketo, M.M.6
Von Boehmer, H.7
-
168
-
-
0028985161
-
An HMG-box-containing T-cell factor required for thymocyte differentiation
-
Verbeek S, Izon D, Hofhuis F, Robanus-Maandag E, te Riele H, van de Wetering M, Oosterwegel M, Wilson A, MacDonald HR, Clevers H. An HMG-box-containing T-cell factor required for thymocyte differentiation. Nature 1995; 374:70-74.
-
(1995)
Nature
, vol.374
, pp. 70-74
-
-
Verbeek, S.1
Izon, D.2
Hofhuis, F.3
Robanus-Maandag, E.4
Te Riele, H.5
Van De Wetering, M.6
Oosterwegel, M.7
Wilson, A.8
MacDonald, H.R.9
Clevers, H.10
-
169
-
-
0031883962
-
Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1
-
Okamura RM, Sigvardsson M, Galceran J, Verbeek S, Clevers H, Grosschedl R. Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1. Immunity 1998; 8:11-20.
-
(1998)
Immunity
, vol.8
, pp. 11-20
-
-
Okamura, R.M.1
Sigvardsson, M.2
Galceran, J.3
Verbeek, S.4
Clevers, H.5
Grosschedl, R.6
-
170
-
-
0346121607
-
Deletion of beta-catenin impairs T cell development
-
Xu Y, Banerjee D, Huelsken J, Birchmeier W, Sen JM. Deletion of beta-catenin impairs T cell development. Nat Immunol 2003; 4:1177-1182.
-
(2003)
Nat Immunol
, vol.4
, pp. 1177-1182
-
-
Xu, Y.1
Banerjee, D.2
Huelsken, J.3
Birchmeier, W.4
Sen, J.M.5
-
171
-
-
4143151485
-
IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: Impact on thymocyte development
-
Yu Q, Erman B, Park JH, Feigenbaum L, Singer A. IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development. J Exp Med 2004; 200: 797-803.
-
(2004)
J Exp Med
, vol.200
, pp. 797-803
-
-
Yu, Q.1
Erman, B.2
Park, J.H.3
Feigenbaum, L.4
Singer, A.5
-
172
-
-
0001003110
-
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
-
Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, Korinek V, Roose J, Destree O, Clevers H. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 1996; 86:391-399.
-
(1996)
Cell
, vol.86
, pp. 391-399
-
-
Molenaar, M.1
Van De Wetering, M.2
Oosterwegel, M.3
Peterson-Maduro, J.4
Godsave, S.5
Korinek, V.6
Roose, J.7
Destree, O.8
Clevers, H.9
-
173
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 1996; 382:638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
Von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
174
-
-
0036125058
-
Interleukin-7 negatively regulates the development of mature T cells in fetal thymus organ cultures
-
DeLuca D, Clark DR. Interleukin-7 negatively regulates the development of mature T cells in fetal thymus organ cultures. Dev Comp Immunol 2002; 26:365-384.
-
(2002)
Dev Comp Immunol
, vol.26
, pp. 365-384
-
-
DeLuca, D.1
Clark, D.R.2
-
175
-
-
0027174226
-
Exogenous IL-7 promotes the growth of CD3-CD4-CD8-CD44+ CD25+/- Precursor cells and blocks the differentiation pathway of TCR-alpha beta cells in fetal thymus organ culture
-
Plum J, De Smedt M, Leclercq G. Exogenous IL-7 promotes the growth of CD3-CD4-CD8-CD44+ CD25+/- precursor cells and blocks the differentiation pathway of TCR-alpha beta cells in fetal thymus organ culture. J Immunol 1993; 150:2706-2716.
-
(1993)
J Immunol
, vol.150
, pp. 2706-2716
-
-
Plum, J.1
De Smedt, M.2
Leclercq, G.3
-
176
-
-
0041967288
-
Thymic epithelial cells provide WNT signals to developing thymocytes
-
Pongracz J, Hare K, Harman B, Anderson G, Jenkinson EJ. Thymic epithelial cells provide WNT signals to developing thymocytes. Eur J Immunol 2003; 33: 1949-1956.
-
(2003)
Eur J Immunol
, vol.33
, pp. 1949-1956
-
-
Pongracz, J.1
Hare, K.2
Harman, B.3
Anderson, G.4
Jenkinson, E.J.5
-
177
-
-
0036232701
-
Wnt-1 and Wnt-4 regulate thymic cellularity
-
Mulroy T, McMahon JA, Burakoff SJ, McMahon AP, Sen J. Wnt-1 and Wnt-4 regulate thymic cellularity. Eur J Immunol 2002; 32:967-971.
-
(2002)
Eur J Immunol
, vol.32
, pp. 967-971
-
-
Mulroy, T.1
McMahon, J.A.2
Burakoff, S.J.3
McMahon, A.P.4
Sen, J.5
-
178
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes Dev 2001; 15:3059-3087.
-
(2001)
Genes Dev
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
179
-
-
0033712944
-
Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte
-
Outram SV, Varas A, Pepicelli CV, Crompton T. Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte. Immunity 2000; 13:187-197.
-
(2000)
Immunity
, vol.13
, pp. 187-197
-
-
Outram, S.V.1
Varas, A.2
Pepicelli, C.V.3
Crompton, T.4
-
180
-
-
0842343439
-
Reduced thymocyte development in sonic hedgehog knockout embryos
-
Shah DK, Hager-Theodorides AL, Outram SV, Ross SE, Varas A, Crompton T. Reduced thymocyte development in sonic hedgehog knockout embryos. J Immunol 2004; 172:2296-2306.
-
(2004)
J Immunol
, vol.172
, pp. 2296-2306
-
-
Shah, D.K.1
Hager-Theodorides, A.L.2
Outram, S.V.3
Ross, S.E.4
Varas, A.5
Crompton, T.6
-
182
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas S, Rand MD, Lake RJ. Notch signaling: cell fate control and signal integration in development. Science 1999; 284:770-776.
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
183
-
-
0033868818
-
A novel proteolytic cleavage involved in Notch signaling: The role of the disintegrin-metalloprotease TACE
-
Brou C, Logeat F, Gupta N, Bessia C, LeBail O, Doedens JR, Cumano A, Roux P, Black RA, Israel A. A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. Mol Cell 2000; 5:207-216.
-
(2000)
Mol Cell
, vol.5
, pp. 207-216
-
-
Brou, C.1
Logeat, F.2
Gupta, N.3
Bessia, C.4
Lebail, O.5
Doedens, J.R.6
Cumano, A.7
Roux, P.8
Black, R.A.9
Israel, A.10
-
184
-
-
0033867521
-
A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1
-
Mumm JS, Schroeter EH, Saxena MT, Griesemer A, Tian X, Pan DJ, Ray WJ, Kopan R. A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1. Mol Cell 2000; 5:197-206.
-
(2000)
Mol Cell
, vol.5
, pp. 197-206
-
-
Mumm, J.S.1
Schroeter, E.H.2
Saxena, M.T.3
Griesemer, A.4
Tian, X.5
Pan, D.J.6
Ray, W.J.7
Kopan, R.8
-
185
-
-
0037133688
-
Notch receptor cleavage depends on but is not directly executed by presenilins
-
Taniguchi Y, Karlstrom H, Lundkvist J, Mizutani T, Otaka A, Vestling M, Bernstein A, Donoviel D, Lendahl U, Honjo T. Notch receptor cleavage depends on but is not directly executed by presenilins. Proc Natl Acad Sci U S A 2002; 99:4014-4019.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 4014-4019
-
-
Taniguchi, Y.1
Karlstrom, H.2
Lundkvist, J.3
Mizutani, T.4
Otaka, A.5
Vestling, M.6
Bernstein, A.7
Donoviel, D.8
Lendahl, U.9
Honjo, T.10
-
186
-
-
0033535504
-
A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper B, Annaert W, Cupers P, Saftig P, Craessaerts K, Mumm JS, Schroeter EH, Schrijvers V, Wolfe MS, Ray WJ, Goate A, Kopan R. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 1999; 398:518-522.
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
Annaert, W.2
Cupers, P.3
Saftig, P.4
Craessaerts, K.5
Mumm, J.S.6
Schroeter, E.H.7
Schrijvers, V.8
Wolfe, M.S.9
Ray, W.J.10
Goate, A.11
Kopan, R.12
-
187
-
-
0028171718
-
The suppressor of hairless protein participates in notch receptor signaling
-
Fortini ME, Artavanis-Tsakonas S. The suppressor of hairless protein participates in notch receptor signaling. Cell 1994; 79:273-282.
-
(1994)
Cell
, vol.79
, pp. 273-282
-
-
Fortini, M.E.1
Artavanis-Tsakonas, S.2
-
188
-
-
0029085935
-
Signalling downstream of activated mammalian Notch
-
Jarriault S, Brou C, Logeat F, Schroeter EH, Kopan R, Israel A. Signalling downstream of activated mammalian Notch. Nature 1995; 377:355-358.
-
(1995)
Nature
, vol.377
, pp. 355-358
-
-
Jarriault, S.1
Brou, C.2
Logeat, F.3
Schroeter, E.H.4
Kopan, R.5
Israel, A.6
-
189
-
-
0029942842
-
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles
-
Pear WS, Aster JC, Scott ML, Hasserjian RP, Soffer B, Sklar J, Baltimore D. Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles. J Exp Med 1996; 183:2283-2291.
-
(1996)
J Exp Med
, vol.183
, pp. 2283-2291
-
-
Pear, W.S.1
Aster, J.C.2
Scott, M.L.3
Hasserjian, R.P.4
Soffer, B.5
Sklar, J.6
Baltimore, D.7
-
190
-
-
20244389684
-
Notch1 expression in early lymphopoiesis influences B versus T lineage determination
-
Pui JC, Allman D, Xu L, DeRocco S, Karnell FG, Bakkour S, Lee JY, Kadesch T, Hardy RR, Aster JC, Pear WS. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 1999; 11:299-308.
-
(1999)
Immunity
, vol.11
, pp. 299-308
-
-
Pui, J.C.1
Allman, D.2
Xu, L.3
DeRocco, S.4
Karnell, F.G.5
Bakkour, S.6
Lee, J.Y.7
Kadesch, T.8
Hardy, R.R.9
Aster, J.C.10
Pear, W.S.11
-
191
-
-
0033136717
-
Deficient T cell fate specification in mice with an induced inactivation of Notch1
-
Radtke F, Wilson A, Stark G, Bauer M, van Meerwijk J, MacDonald HR, Aguet M. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 1999; 10:547-558.
-
(1999)
Immunity
, vol.10
, pp. 547-558
-
-
Radtke, F.1
Wilson, A.2
Stark, G.3
Bauer, M.4
Van Meerwijk, J.5
MacDonald, H.R.6
Aguet, M.7
-
192
-
-
0035988246
-
Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
-
Han H, Tanigaki K, Yamamoto N, Kuroda K, Yoshimoto M, Nakahata T, Ikuta K, Honjo T. Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. Int Immunol 2002; 14:637-645.
-
(2002)
Int Immunol
, vol.14
, pp. 637-645
-
-
Han, H.1
Tanigaki, K.2
Yamamoto, N.3
Kuroda, K.4
Yoshimoto, M.5
Nakahata, T.6
Ikuta, K.7
Honjo, T.8
-
193
-
-
4444328365
-
Mastermind critically regulates Notch-mediated lymphoid cell fate decisions
-
Maillard I, Weng AP, Carpenter AC, Rodriguez CG, Sai H, Xu L, Allman D, Aster JC, Pear WS. Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. Blood 2004; 104:1696-1702.
-
(2004)
Blood
, vol.104
, pp. 1696-1702
-
-
Maillard, I.1
Weng, A.P.2
Carpenter, A.C.3
Rodriguez, C.G.4
Sai, H.5
Xu, L.6
Allman, D.7
Aster, J.C.8
Pear, W.S.9
-
194
-
-
0035979234
-
Presenilin-dependent gamma-secretase activity modulates thymocyte development
-
Doerfler P, Shearman MS, Perlmutter RM. Presenilin-dependent gamma-secretase activity modulates thymocyte development. Proc Natl Acad Sci U S A 2001; 98:9312-9317.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9312-9317
-
-
Doerfler, P.1
Shearman, M.S.2
Perlmutter, R.M.3
-
195
-
-
0033135269
-
The bHLH gene Hes1 is essential for expansion of early T cell precursors
-
Tomita K, Hattori M, Nakamura E, Nakanishi S, Minato N, Kageyama R. The bHLH gene Hes1 is essential for expansion of early T cell precursors. Genes Dev 1999; 13:1203-1210.
-
(1999)
Genes Dev
, vol.13
, pp. 1203-1210
-
-
Tomita, K.1
Hattori, M.2
Nakamura, E.3
Nakanishi, S.4
Minato, N.5
Kageyama, R.6
-
196
-
-
0036070308
-
Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha/beta lineage thymocytes
-
Wolfer A, Wilson A, Nemir M, MacDonald HR, Radtke F. Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha/beta lineage thymocytes. Immunity 2002; 16:869-879.
-
(2002)
Immunity
, vol.16
, pp. 869-879
-
-
Wolfer, A.1
Wilson, A.2
Nemir, M.3
MacDonald, H.R.4
Radtke, F.5
-
197
-
-
2142654263
-
Obligatory role for cooperative signaling by preTCR and Notch during thymocyte differentiation
-
Ciofani M, Schmitt TM, Ciofani A, Michie AM, Cuburu N, Aublin A, Maryanski JL, Zuniga-Pflucker JC. Obligatory role for cooperative signaling by preTCR and Notch during thymocyte differentiation. J Immunol 2004; 172:5230-5239.
-
(2004)
J Immunol
, vol.172
, pp. 5230-5239
-
-
Ciofani, M.1
Schmitt, T.M.2
Ciofani, A.3
Michie, A.M.4
Cuburu, N.5
Aublin, A.6
Maryanski, J.L.7
Zuniga-Pflucker, J.C.8
-
198
-
-
0041428109
-
Surface expression of Notch1 on thymocytes: Correlation with the double-negative to double-positive transition
-
Huang EY, Gallegos AM, Richards SM, Lehar SM, Bevan MJ. Surface expression of Notch1 on thymocytes: correlation with the double-negative to double-positive transition. J Immunol 2003; 171:2296-2304.
-
(2003)
J Immunol
, vol.171
, pp. 2296-2304
-
-
Huang, E.Y.1
Gallegos, A.M.2
Richards, S.M.3
Lehar, S.M.4
Bevan, M.J.5
-
199
-
-
0035796488
-
Separation of Notch1 promoted lineage commitment and expansion/ transformation in developing T cells
-
Allman D, Karnell FG, Punt JA, Bakkour S, Xu L, Myung P, Koretzky GA, Pui JC, Aster JC, Pear WS. Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells. J Exp Med 2001; 194:99-106.
-
(2001)
J Exp Med
, vol.194
, pp. 99-106
-
-
Allman, D.1
Karnell, F.G.2
Punt, J.A.3
Bakkour, S.4
Xu, L.5
Myung, P.6
Koretzky, G.A.7
Pui, J.C.8
Aster, J.C.9
Pear, W.S.10
-
200
-
-
0037133497
-
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis
-
Bellavia D, Campese AF, Checquolo S, Balestri A, Biondi A, Cazzaniga G, Lendahl U, Fehling HJ, Hayday AC, Frati L, von Boehmer H, Gulino A, Screpanti I. Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis. Proc Natl Acad Sci U S A 2002; 99:3788-3793.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3788-3793
-
-
Bellavia, D.1
Campese, A.F.2
Checquolo, S.3
Balestri, A.4
Biondi, A.5
Cazzaniga, G.6
Lendahl, U.7
Fehling, H.J.8
Hayday, A.C.9
Frati, L.10
Von Boehmer, H.11
Gulino, A.12
Screpanti, I.13
-
201
-
-
0031001247
-
Notch activity influences the alphabeta versus gammadelta T cell lineage decision
-
Washburn T, Schweighoffer E, Gridley T, Chang D, Fowlkes BJ, Cado D, Robey E. Notch activity influences the alphabeta versus gammadelta T cell lineage decision. Cell 1997; 88:833-843.
-
(1997)
Cell
, vol.88
, pp. 833-843
-
-
Washburn, T.1
Schweighoffer, E.2
Gridley, T.3
Chang, D.4
Fowlkes, B.J.5
Cado, D.6
Robey, E.7
-
202
-
-
2442522357
-
Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
-
Tanigaki K, Tsuji M, Yamamoto N, Han H, Tsukada J, Inoue H, Kubo M, Honjo T. Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity 2004; 20:611-622.
-
(2004)
Immunity
, vol.20
, pp. 611-622
-
-
Tanigaki, K.1
Tsuji, M.2
Yamamoto, N.3
Han, H.4
Tsukada, J.5
Inoue, H.6
Kubo, M.7
Honjo, T.8
-
203
-
-
0141816703
-
Sustained Notch1 signaling instructs the earliest human intrathymic precursors to adopt a gammadelta T-cell fate in fetal thymus organ culture
-
Garcia-Peydro M, de Yebenes VG, Toribio ML. Sustained Notch1 signaling instructs the earliest human intrathymic precursors to adopt a gammadelta T-cell fate in fetal thymus organ culture. Blood 2003; 102:2444-2451.
-
(2003)
Blood
, vol.102
, pp. 2444-2451
-
-
Garcia-Peydro, M.1
De Yebenes, V.G.2
Toribio, M.L.3
-
204
-
-
0032054238
-
Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice
-
Jiang R, Lan Y, Chapman HD, Shawber C, Norton CR, Serreze DV, Weinmaster G, Gridley T. Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice. Genes Dev 1998; 12:1046-1057.
-
(1998)
Genes Dev
, vol.12
, pp. 1046-1057
-
-
Jiang, R.1
Lan, Y.2
Chapman, H.D.3
Shawber, C.4
Norton, C.R.5
Serreze, D.V.6
Weinmaster, G.7
Gridley, T.8
-
205
-
-
0034671940
-
MHC recognition in thymic development: Distinct, parallel pathways for survival and lineage commitment
-
Chang D, Valdez P, Ho T, Robey E. MHC recognition in thymic development: distinct, parallel pathways for survival and lineage commitment. J Immunol 2000; 165:6710-6715.
-
(2000)
J Immunol
, vol.165
, pp. 6710-6715
-
-
Chang, D.1
Valdez, P.2
Ho, T.3
Robey, E.4
-
206
-
-
0030297895
-
An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
-
Robey E, Chang D, Itano A, Cado D, Alexander H, Lans D, Weinmaster G, Salmon P. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages. Cell 1996; 87:483-492.
-
(1996)
Cell
, vol.87
, pp. 483-492
-
-
Robey, E.1
Chang, D.2
Itano, A.3
Cado, D.4
Alexander, H.5
Lans, D.6
Weinmaster, G.7
Salmon, P.8
-
207
-
-
17744363445
-
Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength
-
Izon DJ, Punt JA, Xu L, Karnell FG, Allman D, Myung PS, Boerth NJ, Pui JC, Koretzky GA, Pear WS. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength. Immunity 2001; 14:253-264.
-
(2001)
Immunity
, vol.14
, pp. 253-264
-
-
Izon, D.J.1
Punt, J.A.2
Xu, L.3
Karnell, F.G.4
Allman, D.5
Myung, P.S.6
Boerth, N.J.7
Pui, J.C.8
Koretzky, G.A.9
Pear, W.S.10
-
208
-
-
5844299536
-
Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development
-
Wolfer A, Bakker T, Wilson A, Nicolas M, Ioannidis V, Littman DR, Wilson CB, Held W, MacDonald HR, Radtke F. Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development. Nat Immunol 2001; 2:235-241.
-
(2001)
Nat Immunol
, vol.2
, pp. 235-241
-
-
Wolfer, A.1
Bakker, T.2
Wilson, A.3
Nicolas, M.4
Ioannidis, V.5
Littman, D.R.6
Wilson, C.B.7
Held, W.8
MacDonald, H.R.9
Radtke, F.10
-
209
-
-
0032442040
-
Correlating notch signaling with thymocyte maturation
-
Deftos ML, He YW, Ojala EW, Bevan MJ. Correlating notch signaling with thymocyte maturation. Immunity 1998; 9:777-786.
-
(1998)
Immunity
, vol.9
, pp. 777-786
-
-
Deftos, M.L.1
He, Y.W.2
Ojala, E.W.3
Bevan, M.J.4
-
210
-
-
0033681301
-
Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
-
Deftos ML, Huang E, Ojala EW, Forbush KA, Bevan MJ. Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes. Immunity 2000; 13:73-84.
-
(2000)
Immunity
, vol.13
, pp. 73-84
-
-
Deftos, M.L.1
Huang, E.2
Ojala, E.W.3
Forbush, K.A.4
Bevan, M.J.5
-
211
-
-
0347089094
-
T-cell development made simple
-
Zuniga-Pflucker JC. T-cell development made simple. Nat Rev Immunol 2004; 4:67-72.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 67-72
-
-
Zuniga-Pflucker, J.C.1
-
212
-
-
0036916440
-
Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
-
Schmitt TM, Zúñiga-Pflücker JC. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity 2002; 17:749-756.
-
(2002)
Immunity
, vol.17
, pp. 749-756
-
-
Schmitt, T.M.1
Zúñiga-Pflücker, J.C.2
-
213
-
-
3042627641
-
Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro
-
Schmitt TM, de Pooter RF, Gronski MA, Cho SK, Ohashi PS, Zuniga-Pflucker JC. Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nat Immunol 2004; 5:410-417.
-
(2004)
Nat Immunol
, vol.5
, pp. 410-417
-
-
Schmitt, T.M.1
De Pooter, R.F.2
Gronski, M.A.3
Cho, S.K.4
Ohashi, P.S.5
Zuniga-Pflucker, J.C.6
-
214
-
-
4644265888
-
Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors
-
Hoflinger S, Kesavan K, Fuxa M, Hutter C, Heavey B, Radtke F, Busslinger M. Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J Immunol 2004; 173: 3935-3944.
-
(2004)
J Immunol
, vol.173
, pp. 3935-3944
-
-
Hoflinger, S.1
Kesavan, K.2
Fuxa, M.3
Hutter, C.4
Heavey, B.5
Radtke, F.6
Busslinger, M.7
-
215
-
-
0019990965
-
Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: Application in the production of chimeric thymus rudiments
-
Jenkinson EJ, Franchi LL, Kingston R, Owen JJ. Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: application in the production of chimeric thymus rudiments. Eur J Immunol 1982; 12:583-587.
-
(1982)
Eur J Immunol
, vol.12
, pp. 583-587
-
-
Jenkinson, E.J.1
Franchi, L.L.2
Kingston, R.3
Owen, J.J.4
|