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Volumn 189, Issue 2, 1999, Pages 289-300

Positive and negative regulation of V(D)J recombination by the E2A proteins

Author keywords

and ; E2A; Rearrangement; T cell receptor

Indexed keywords

GENE PRODUCT; T LYMPHOCYTE RECEPTOR;

EID: 0033579803     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.2.289     Document Type: Article
Times cited : (107)

References (81)
  • 1
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. 1983. Somatic generation of antibody diversity. Nature. 302:575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 2
    • 0026708716 scopus 로고
    • V(D)J recombination: Molecular biology and regulation
    • Schatz, D., M. Oettinger, and M. Schlissel. 1992. V(D)J recombination: molecular biology and regulation. Annu. Rev. Immunol. 10:359-383.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 359-383
    • Schatz, D.1    Oettinger, M.2    Schlissel, M.3
  • 3
    • 0025301095 scopus 로고
    • RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination
    • Oettinger, M., D. Schatz, C. Gorka, and D. Baltimore. 1990. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science. 248:1517-1523.
    • (1990) Science , vol.248 , pp. 1517-1523
    • Oettinger, M.1    Schatz, D.2    Gorka, C.3    Baltimore, D.4
  • 4
    • 0028805853 scopus 로고
    • Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps
    • McBlane, J., D. van Gent, D. Ramsden, C. Romeo, C. Cuomo, M. Gellert, and M. Oettinger. 1995. Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps. Cell. 83:387-395.
    • (1995) Cell , vol.83 , pp. 387-395
    • McBlane, J.1    Van Gent, D.2    Ramsden, D.3    Romeo, C.4    Cuomo, C.5    Gellert, M.6    Oettinger, M.7
  • 7
    • 0024846088 scopus 로고
    • The V(D)J recombination activating gene, Rag-1
    • Schatz, D., M. Oettinger, and D. Baltimore. 1989. The V(D)J recombination activating gene, Rag-1. Cell. 59:1035-1048.
    • (1989) Cell , vol.59 , pp. 1035-1048
    • Schatz, D.1    Oettinger, M.2    Baltimore, D.3
  • 8
    • 0027221908 scopus 로고
    • Gene rearrangement and B cell development
    • Chen, J., and F.W. Alt. 1993. Gene rearrangement and B cell development. Curr. Opin. Immunol. 5:194-200.
    • (1993) Curr. Opin. Immunol. , vol.5 , pp. 194-200
    • Chen, J.1    Alt, F.W.2
  • 10
    • 0028872616 scopus 로고
    • Development and selection of T cells: Facts and puzzles
    • Kisielow, P., and H. von Boehmer. 1995. Development and selection of T cells: facts and puzzles. Adv. Immunol. 58:87-209.
    • (1995) Adv. Immunol. , vol.58 , pp. 87-209
    • Kisielow, P.1    Von Boehmer, H.2
  • 11
    • 0024339411 scopus 로고
    • Developmental biology of T cell receptors
    • Strominger, J. 1989. Developmental biology of T cell receptors. Science. 244:943-950.
    • (1989) Science , vol.244 , pp. 943-950
    • Strominger, J.1
  • 12
    • 0029894165 scopus 로고    scopus 로고
    • Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
    • Stanhope-Baker, P., K. Hudson, A. Shaffer, A. Constantinescu, and M. Schlissel. 1996. Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell 85:887-897.
    • (1996) Cell , vol.85 , pp. 887-897
    • Stanhope-Baker, P.1    Hudson, K.2    Shaffer, A.3    Constantinescu, A.4    Schlissel, M.5
  • 13
    • 0029983727 scopus 로고    scopus 로고
    • Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements
    • Sleckman, B., J. Gorman, and F. Alt. 1996. Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements. Annu. Rev. Immunol. 14:459-481.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 459-481
    • Sleckman, B.1    Gorman, J.2    Alt, F.3
  • 14
    • 0023684162 scopus 로고
    • Developmentally regulated and strain-specific expression of murine VH gene families
    • Yancopoulos, G., B. Malynn, and F. Alt. 1988. Developmentally regulated and strain-specific expression of murine VH gene families. J. Exp. Med. 168:417-435.
    • (1988) J. Exp. Med. , vol.168 , pp. 417-435
    • Yancopoulos, G.1    Malynn, B.2    Alt, F.3
  • 15
    • 0023054151 scopus 로고
    • VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay
    • Wu, G., and C. Paige. 1986. VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay. EMBO (Eur. Mol. Biol. Organ.) J. 5:3475-3481.
    • (1986) EMBO (Eur. Mol. Biol. Organ.) J. , vol.5 , pp. 3475-3481
    • Wu, G.1    Paige, C.2
  • 16
    • 0029670173 scopus 로고    scopus 로고
    • Frequency of VH81X usage during B cell development. Initial decline in usage is independent of Ig heavy chain cell surface expression
    • Marshall, A., G. Wu, and C. Paige. 1996. Frequency of VH81X usage during B cell development. Initial decline in usage is independent of Ig heavy chain cell surface expression. J. Immunol. 156:2077-2084.
    • (1996) J. Immunol. , vol.156 , pp. 2077-2084
    • Marshall, A.1    Wu, G.2    Paige, C.3
  • 17
    • 0022272091 scopus 로고
    • VH-gene expression in murine lipopolysaccharide blasts distributes over the nine known VH-gene groups and may be random
    • Dildrop, R., U. Krawinkel, E. Winter, and K. Rajewsky. 1985. VH-gene expression in murine lipopolysaccharide blasts distributes over the nine known VH-gene groups and may be random. Eur. J. Immunol. 15:1154-1156.
    • (1985) Eur. J. Immunol. , vol.15 , pp. 1154-1156
    • Dildrop, R.1    Krawinkel, U.2    Winter, E.3    Rajewsky, K.4
  • 18
    • 0024409954 scopus 로고
    • The structure, function, and molecular genetics of the γ/δ T cell receptor
    • Raulet, D. 1989. The structure, function, and molecular genetics of the γ/δ T cell receptor. Annu. Rev. Immunol. 7:175-207.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 175-207
    • Raulet, D.1
  • 20
    • 0023690608 scopus 로고
    • Developmentally ordered appearance of thymocytes expressing different T cell antigen receptors
    • Havran, W., and J. Allison. 1988. Developmentally ordered appearance of thymocytes expressing different T cell antigen receptors. Nature. 335:443-445.
    • (1988) Nature , vol.335 , pp. 443-445
    • Havran, W.1    Allison, J.2
  • 21
    • 0023043253 scopus 로고
    • Diversity, rearrangement and expression of murine T cell gamma genes
    • Garman, R., P. Doherty, and D. Raulet. 1986. Diversity, rearrangement and expression of murine T cell gamma genes. Cell. 45:733-742.
    • (1986) Cell , vol.45 , pp. 733-742
    • Garman, R.1    Doherty, P.2    Raulet, D.3
  • 22
    • 0027400624 scopus 로고
    • Ordered rearrangement of variable region genes of the T cell receptor γ locus correlates with transcription of the unrearranged genes
    • Goldman, J., D. Spencer, and D. Raulet. 1993. Ordered rearrangement of variable region genes of the T cell receptor γ locus correlates with transcription of the unrearranged genes. J. Exp. Med. 177:729-739.
    • (1993) J. Exp. Med. , vol.177 , pp. 729-739
    • Goldman, J.1    Spencer, D.2    Raulet, D.3
  • 23
    • 0023760731 scopus 로고
    • Variable region (Vδ) gene segment most frequently utilized in adult thymocytes is 3′ of the constant (Cδ) region
    • Iwashima, M., A. Green, M. Davis, and Y. Chien. 1988. Variable region (Vδ) gene segment most frequently utilized in adult thymocytes is 3′ of the constant (Cδ) region. Proc. Natl. Acad. Sci. USA. 85:8161-8165.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8161-8165
    • Iwashima, M.1    Green, A.2    Davis, M.3    Chien, Y.4
  • 25
    • 0031171282 scopus 로고    scopus 로고
    • Accessibility and the developmental regulation of V(D)J recombination
    • Schlissel, M., and P. Stanhope-Baker. 1997. Accessibility and the developmental regulation of V(D)J recombination. Semin. Immunol. 9:161-170.
    • (1997) Semin. Immunol. , vol.9 , pp. 161-170
    • Schlissel, M.1    Stanhope-Baker, P.2
  • 26
    • 0026625805 scopus 로고
    • Regulation of immunoglobulin gene transcription
    • Nelsen, B., and R. Sen. 1992. Regulation of immunoglobulin gene transcription. Int. Rev. Cytol. 133:121-148.
    • (1992) Int. Rev. Cytol. , vol.133 , pp. 121-148
    • Nelsen, B.1    Sen, R.2
  • 28
    • 0026798829 scopus 로고
    • Helix loop helix proteins in the regulation of immunoglobulin gene transcription
    • Kadesch, T. 1992. Helix loop helix proteins in the regulation of immunoglobulin gene transcription. Immunol. Today. 13: 31-36.
    • (1992) Immunol. Today , vol.13 , pp. 31-36
    • Kadesch, T.1
  • 30
    • 0028088556 scopus 로고
    • Constitutive expression of the Id1 gene impairs mouse B cell development
    • Sun, X.-H. 1994. Constitutive expression of the Id1 gene impairs mouse B cell development. Cell. 79:893-900.
    • (1994) Cell , vol.79 , pp. 893-900
    • Sun, X.-H.1
  • 31
    • 0028148938 scopus 로고
    • The helix-loop-helix gene E2A is required for B cell formation
    • Zhuang, Y., P. Soriano, and H. Weintraub. 1994. The helix-loop-helix gene E2A is required for B cell formation. Cell. 79:875-884.
    • (1994) Cell , vol.79 , pp. 875-884
    • Zhuang, Y.1    Soriano, P.2    Weintraub, H.3
  • 34
    • 0032541471 scopus 로고    scopus 로고
    • Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12
    • Kee, B., and C. Murre. 1998. Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12. J. Exp. Med. 188:699-713.
    • (1998) J. Exp. Med. , vol.188 , pp. 699-713
    • Kee, B.1    Murre, C.2
  • 36
    • 0026045243 scopus 로고
    • Helix loop helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line
    • Schlissel, M., A. Voronova, and D. Baltimore. 1991. Helix loop helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line. Genes Dev. 5:1367-1376.
    • (1991) Genes Dev. , vol.5 , pp. 1367-1376
    • Schlissel, M.1    Voronova, A.2    Baltimore, D.3
  • 37
    • 0030790713 scopus 로고    scopus 로고
    • EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes
    • Sigvardsson, M., M. O'Riordan, and R. Grosschedl. 1997. EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes. Immunity. 7:25-36.
    • (1997) Immunity , vol.7 , pp. 25-36
    • Sigvardsson, M.1    O'Riordan, M.2    Grosschedl, R.3
  • 38
    • 0028117098 scopus 로고
    • Modulation of epithelial cell growth by intraepithelial γδ T cells
    • Boismenu, R., and W. Havran. 1994. Modulation of epithelial cell growth by intraepithelial γδ T cells. Science. 266: 1253-1255.
    • (1994) Science , vol.266 , pp. 1253-1255
    • Boismenu, R.1    Havran, W.2
  • 39
    • 0029054748 scopus 로고
    • In-frame TCR δ gene rearrangements play a critical role in the αβ/γδ T cell lineage decision
    • Livak, F., H. Patrie, I. Crispe, and D. Schatz. 1995. In-frame TCR δ gene rearrangements play a critical role in the αβ/γδ T cell lineage decision. Immunity. 2:617-627.
    • (1995) Immunity , vol.2 , pp. 617-627
    • Livak, F.1    Patrie, H.2    Crispe, I.3    Schatz, D.4
  • 40
    • 0024276527 scopus 로고
    • Limited diversity of γδ antigen receptor genes of thy-1 + dendritic epidermal cells
    • Asarnow, D., W. Kuziel, M. Bonyhadi, R. Tigelaar, P. Tucker, and J. Allison. 1988. Limited diversity of γδ antigen receptor genes of thy-1 + dendritic epidermal cells. Cell. 55: 837-847.
    • (1988) Cell , vol.55 , pp. 837-847
    • Asarnow, D.1    Kuziel, W.2    Bonyhadi, M.3    Tigelaar, R.4    Tucker, P.5    Allison, J.6
  • 41
    • 0024440089 scopus 로고
    • Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells
    • Asarnow, D., T. Goodman, L. LeFrancois, and J. Allison. 1989. Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells. Nature. 341:60-62.
    • (1989) Nature , vol.341 , pp. 60-62
    • Asarnow, D.1    Goodman, T.2    LeFrancois, L.3    Allison, J.4
  • 42
    • 0027491330 scopus 로고
    • Characterization of broken DNA molecules associated with V(D)J recombination
    • Roth, D., C. Zhu, and M. Gellert. 1993. Characterization of broken DNA molecules associated with V(D)J recombination. Proc. Natl. Acad. Sci. USA. 90:10788-10792.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10788-10792
    • Roth, D.1    Zhu, C.2    Gellert, M.3
  • 43
    • 0027769386 scopus 로고
    • Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated
    • Schlissel, M., A. Constantinescu, T. Morrow, M. Baxter, and A. Peng. 1993. Double-strand signal sequence breaks in V(D)J recombination are blunt, 5′-phosphorylated, RAG-dependent, and cell cycle regulated. Genes Dev. 7:2520-2532.
    • (1993) Genes Dev. , vol.7 , pp. 2520-2532
    • Schlissel, M.1    Constantinescu, A.2    Morrow, T.3    Baxter, M.4    Peng, A.5
  • 44
    • 0030665673 scopus 로고    scopus 로고
    • Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3
    • Heemskerk, M., B. Blom, G. Nolan, A. Stegmann, A. Bakker, K. Weijer, P. Res, and H. Spits. 1997. Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J. Exp. Med. 186:1597-1602.
    • (1997) J. Exp. Med. , vol.186 , pp. 1597-1602
    • Heemskerk, M.1    Blom, B.2    Nolan, G.3    Stegmann, A.4    Bakker, A.5    Weijer, K.6    Res, P.7    Spits, H.8
  • 45
    • 0026633291 scopus 로고
    • Commitment to the T-cell receptor αβ or γδ lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes
    • Petrie, H., R. Scollay, and K. Shortman. 1992. Commitment to the T-cell receptor αβ or γδ lineages can occur just prior to the onset of CD4 and CD8 expression among immature thymocytes. Eur. J. Immunol 22:2185-2188.
    • (1992) Eur. J. Immunol , vol.22 , pp. 2185-2188
    • Petrie, H.1    Scollay, R.2    Shortman, K.3
  • 46
    • 0027153201 scopus 로고
    • - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150:4244-4252.
    • (1993) J. Immunol. , vol.150 , pp. 4244-4252
    • Godfrey, D.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 47
    • 0029311234 scopus 로고
    • αβ and γδ T cells can share a late common precursor
    • Dudley, E., M. Girardi, M. Owens, and A. Hayday. 1995. αβ and γδ T cells can share a late common precursor. Curr. Biol. 5:659-669.
    • (1995) Curr. Biol. , vol.5 , pp. 659-669
    • Dudley, E.1    Girardi, M.2    Owens, M.3    Hayday, A.4
  • 49
    • 0025109036 scopus 로고
    • Developmentally regulated fetal thymic and extrathymic T-cell receptor γδ gene expression
    • Carding, S., S. Kyes, E. Jenkinson, R. Kingston, K. Bottomly, T. Owen, and A. Hayday. 1990. Developmentally regulated fetal thymic and extrathymic T-cell receptor γδ gene expression. Genes Dev. 4:1304-1315.
    • (1990) Genes Dev. , vol.4 , pp. 1304-1315
    • Carding, S.1    Kyes, S.2    Jenkinson, E.3    Kingston, R.4    Bottomly, K.5    Owen, T.6    Hayday, A.7
  • 50
    • 0024791338 scopus 로고
    • Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for novel intermediate V-(D)-J joining
    • Lafaille, J., A. DeCloux, M. Bonneville, Y. Takagaki, and S. Tonegawa. 1989. Junctional sequences of T cell receptor γδ genes: implications for γδ T cell lineages and for novel intermediate V-(D)-J joining. Cell. 59:859-870.
    • (1989) Cell , vol.59 , pp. 859-870
    • Lafaille, J.1    DeCloux, A.2    Bonneville, M.3    Takagaki, Y.4    Tonegawa, S.5
  • 51
    • 0026069581 scopus 로고
    • Regulated expression and structure of T cell receptor γ/δ transcripts in human thymic ontogeny
    • McVay, L., S. Carding, K. Bottomly, and A. Hayday. 1991. Regulated expression and structure of T cell receptor γ/δ transcripts in human thymic ontogeny. EMBO (Eur. Mol. Biol. Organ.) J. 10:83-91.
    • (1991) EMBO (Eur. Mol. Biol. Organ.) J. , vol.10 , pp. 83-91
    • McVay, L.1    Carding, S.2    Bottomly, K.3    Hayday, A.4
  • 52
    • 0023873953 scopus 로고
    • The adult T-cell receptor δ-chain is diverse and distinct from that of fetal thymocytes
    • Elliot, J., E. Rock, P. Patten, M. Davis, and Y. Chien. 1988. The adult T-cell receptor δ-chain is diverse and distinct from that of fetal thymocytes. Nature. 331:627-631.
    • (1988) Nature , vol.331 , pp. 627-631
    • Elliot, J.1    Rock, E.2    Patten, P.3    Davis, M.4    Chien, Y.5
  • 53
    • 0022475348 scopus 로고
    • Diversity of murine gamma genes and expression in fetal and adult T lymphocytes
    • Heilig, J., and S. Tonegawa. 1986. Diversity of murine gamma genes and expression in fetal and adult T lymphocytes. Nature. 322:836-840.
    • (1986) Nature , vol.322 , pp. 836-840
    • Heilig, J.1    Tonegawa, S.2
  • 54
    • 0028860551 scopus 로고
    • V-D-J rearrangements at the T cell receptor δ locus in mouse thymocytes of the αβ lineage
    • Nakajima, P., J. Menetski, D. Roth, M. Gellert, and M. Bosma. 1995. V-D-J rearrangements at the T cell receptor δ locus in mouse thymocytes of the αβ lineage. Immunity. 3:609-621.
    • (1995) Immunity , vol.3 , pp. 609-621
    • Nakajima, P.1    Menetski, J.2    Roth, D.3    Gellert, M.4    Bosma, M.5
  • 55
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu, C., M. Bogue, D.-S. Lim, P. Hasty, and D. Roth. 1996. Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell. 86:379-389.
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.1    Bogue, M.2    Lim, D.-S.3    Hasty, P.4    Roth, D.5
  • 57
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
    • Lewis, S. 1994. The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses. Adv. Immunol. 56:27-150.
    • (1994) Adv. Immunol. , vol.56 , pp. 27-150
    • Lewis, S.1
  • 58
    • 0029864993 scopus 로고    scopus 로고
    • Initiation of V(D)J recombination in vitro obeying the 12/23 rule
    • Eastman, Q., T. Leu, and D. Schatz. 1996. Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature. 380:85-88.
    • (1996) Nature , vol.380 , pp. 85-88
    • Eastman, Q.1    Leu, T.2    Schatz, D.3
  • 59
    • 0023002697 scopus 로고
    • Recombination between immunoglobulin variable region gene segments is enhanced by transcription
    • Blackwell, T., M. Moore, G. Yancopoulos, H. Suh, S. Lutzker, E. Selsing, and F. Alt. 1986. Recombination between immunoglobulin variable region gene segments is enhanced by transcription. Nature. 324:585-590.
    • (1986) Nature , vol.324 , pp. 585-590
    • Blackwell, T.1    Moore, M.2    Yancopoulos, G.3    Suh, H.4    Lutzker, S.5    Selsing, E.6    Alt, F.7
  • 61
    • 0025285299 scopus 로고
    • The temporal order of appearance of transcripts from unrearranged and rearranged Ig genes in murine fetal liver
    • Lennon, G., and R. Perry. 1990. The temporal order of appearance of transcripts from unrearranged and rearranged Ig genes in murine fetal liver. J. Immunol. 144:1983-1987.
    • (1990) J. Immunol. , vol.144 , pp. 1983-1987
    • Lennon, G.1    Perry, R.2
  • 62
    • 0026024264 scopus 로고
    • Induced rearrangement of K genes in the BLIN-1 human pre-B cell line correlates with germline J-Cκ and Vκ transcription
    • Martin, D., R. Huang, T. LeBien, and B. VanNess. 1991. Induced rearrangement of K genes in the BLIN-1 human pre-B cell line correlates with germline J-Cκ and Vκ transcription. J. Exp. Med. 173:639-645.
    • (1991) J. Exp. Med. , vol.173 , pp. 639-645
    • Martin, D.1    Huang, R.2    LeBien, T.3    VanNess, B.4
  • 63
    • 0024435908 scopus 로고
    • Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription
    • Schlissel, M.S., and D. Baltimore. 1989. Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription. Cell. 58:1001-1007.
    • (1989) Cell , vol.58 , pp. 1001-1007
    • Schlissel, M.S.1    Baltimore, D.2
  • 64
    • 0021983551 scopus 로고
    • Developmentally controlled and tissue-specific expression of unrearranged VH gene segments
    • Yancopoulos, G., and F.W. Alt. 1985. Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell 40:271-281.
    • (1985) Cell , vol.40 , pp. 271-281
    • Yancopoulos, G.1    Alt, F.W.2
  • 65
    • 0022549940 scopus 로고
    • Introduced T cell receptor variable region gene segments recombine in pre-B cells: Evidence that B and T cells use a common recombinase
    • Yancopoulos, G., T. Blackwell, H. Suh, L. Hood, and F. Alt. 1986. Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase. Cell. 44:251-259.
    • (1986) Cell , vol.44 , pp. 251-259
    • Yancopoulos, G.1    Blackwell, T.2    Suh, H.3    Hood, L.4    Alt, F.5
  • 66
    • 0025034673 scopus 로고
    • Two distinct transcription factors that bind the immunoglobulin enhancer μE5/κE2 motif
    • Henthorn, P., M. Kiledjian, and T. Kadesch. 1990. Two distinct transcription factors that bind the immunoglobulin enhancer μE5/κE2 motif. Science. 247:467-470.
    • (1990) Science , vol.247 , pp. 467-470
    • Henthorn, P.1    Kiledjian, M.2    Kadesch, T.3
  • 67
    • 0024342647 scopus 로고
    • A T-cell-specific transcriptional enhancer element 3′ of Cα in the human T-cell receptor a locus
    • Ho, I.-C., L.-H. Yang, G. Morle, and J. Leiden. 1989. A T-cell-specific transcriptional enhancer element 3′ of Cα in the human T-cell receptor a locus. Proc. Natl. Acad. Sci. USA. 86:6714-6718.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 6714-6718
    • Ho, I.-C.1    Yang, L.-H.2    Morle, G.3    Leiden, J.4
  • 68
    • 0024554495 scopus 로고
    • A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
    • Murre, C., P.S. McCaw, and D. Baltimore. 1989. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell. 56:777-783.
    • (1989) Cell , vol.56 , pp. 777-783
    • Murre, C.1    McCaw, P.S.2    Baltimore, D.3
  • 69
    • 0024997739 scopus 로고
    • Functional analysis of the murine T-cell receptor β enhancer and characteristics of its DNA-binding proteins
    • Takeda, J., A. Cheng, F. Mauxion, C.A. Nelson, R.D. Newberry, W.C. Sha, R. Sen, and D.Y. Loh. 1990. Functional analysis of the murine T-cell receptor β enhancer and characteristics of its DNA-binding proteins. Mol. Cell. Biol. 10: 5027-5035.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5027-5035
    • Takeda, J.1    Cheng, A.2    Mauxion, F.3    Nelson, C.A.4    Newberry, R.D.5    Sha, W.C.6    Sen, R.7    Loh, D.Y.8
  • 70
    • 0028276377 scopus 로고
    • Temporal and lineage-specific control of T cell receptor α/δ gene rearrangement by T cell receptor a and δ enhancers
    • Lauzurica, P., and M. Krangel. 1994. Temporal and lineage-specific control of T cell receptor α/δ gene rearrangement by T cell receptor a and δ enhancers. J. Exp. Med. 179:1913-1921.
    • (1994) J. Exp. Med. , vol.179 , pp. 1913-1921
    • Lauzurica, P.1    Krangel, M.2
  • 72
    • 0028223482 scopus 로고
    • Differential activation of transcription versus recombination of transgenic T cell receptor β variable region gene segments in B and T lineage cells
    • Okada, A., M. Mendelsohn, and F. Alt. 1994. Differential activation of transcription versus recombination of transgenic T cell receptor β variable region gene segments in B and T lineage cells. J. Exp. Med. 180:261-272.
    • (1994) J. Exp. Med. , vol.180 , pp. 261-272
    • Okada, A.1    Mendelsohn, M.2    Alt, F.3
  • 73
    • 0031026910 scopus 로고    scopus 로고
    • Developmental regulation of VDJ recombination by the core fragment of the T cell receptor α enhancer
    • Roberts, J., P. Lauzurica, and M. Krangel. 1997. Developmental regulation of VDJ recombination by the core fragment of the T cell receptor α enhancer. J. Exp. Med. 185: 131-140.
    • (1997) J. Exp. Med. , vol.185 , pp. 131-140
    • Roberts, J.1    Lauzurica, P.2    Krangel, M.3
  • 75
    • 0027168220 scopus 로고
    • Rearrangement and diversity of T cell receptor β chain genes in thymocytes: A critical role for the β chain in development
    • Mallick, C., E. Dudley, J. Viney, M. Owen, and A. Hayday. 1993. Rearrangement and diversity of T cell receptor β chain genes in thymocytes: a critical role for the β chain in development. Cell. 73:513-519.
    • (1993) Cell , vol.73 , pp. 513-519
    • Mallick, C.1    Dudley, E.2    Viney, J.3    Owen, M.4    Hayday, A.5
  • 76
    • 0027406812 scopus 로고
    • Restoration of T-cell development in RAG-2 deficient mice by functional TCR transgenes
    • Shinkai, Y., S. Koyasu, K. Nakayama, K. Murphy, D. Loh, E. Reinherz, and F. Alt. 1993. Restoration of T-cell development in RAG-2 deficient mice by functional TCR transgenes. Science. 259:822-825.
    • (1993) Science , vol.259 , pp. 822-825
    • Shinkai, Y.1    Koyasu, S.2    Nakayama, K.3    Murphy, K.4    Loh, D.5    Reinherz, E.6    Alt, F.7
  • 77
    • 0025266326 scopus 로고
    • A T cell specific transcriptional enhancer within the human T cell receptor δ locus
    • Redondo, J., S. Hata, C. Brocklehurst, and M. Krangel. 1990. A T cell specific transcriptional enhancer within the human T cell receptor δ locus. Science. 247:1225-1229.
    • (1990) Science , vol.247 , pp. 1225-1229
    • Redondo, J.1    Hata, S.2    Brocklehurst, C.3    Krangel, M.4
  • 78
    • 0025941557 scopus 로고
    • Identification of an essential site for transcriptional activation within the human T cell receptor δ enhancer
    • Redondo, J., J. Pfohl, and M. Krangel. 1991. Identification of an essential site for transcriptional activation within the human T cell receptor δ enhancer. Mol. Cell. Biol. 11:5671-5680.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5671-5680
    • Redondo, J.1    Pfohl, J.2    Krangel, M.3
  • 80
    • 0028174032 scopus 로고
    • Functional analysis of the V gamma 3 promoter of the murine gamma delta T-cell receptor
    • Clausell, A., and P. Tucker. 1994. Functional analysis of the V gamma 3 promoter of the murine gamma delta T-cell receptor. Mol. Cell. Biol. 14:803-814.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 803-814
    • Clausell, A.1    Tucker, P.2
  • 81
    • 0029896451 scopus 로고    scopus 로고
    • B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB
    • Zhuang, Y., P. Cheng, and H. Weintraub. 1996. B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB. Mol. Cell. Biol. 16:2898-2905.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2898-2905
    • Zhuang, Y.1    Cheng, P.2    Weintraub, H.3


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