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Volumn 94, Issue 2, 1998, Pages 229-238

Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CD4 ANTIGEN; CD8 ANTIGEN; MONOCLONAL ANTIBODY CD3; T LYMPHOCYTE RECEPTOR;

EID: 0032563256     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81422-1     Document Type: Article
Times cited : (325)

References (53)
  • 1
    • 0031433563 scopus 로고    scopus 로고
    • Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus
    • Aifantis, I., Buer, J., von Boehmer, H., and Azogui, O. (1997). Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus. Immunity 7, 601-607.
    • (1997) Immunity , vol.7 , pp. 601-607
    • Aifantis, I.1    Buer, J.2    Von Boehmer, H.3    Azogui, O.4
  • 2
    • 0026669001 scopus 로고
    • Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn
    • Appleby, M.W., Gross, J.A., Cooke, M.P., Levin, S.D., Qian, X., and Perlmutter, R.M. (1992). Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn. Cell 70, 751-763.
    • (1992) Cell , vol.70 , pp. 751-763
    • Appleby, M.W.1    Gross, J.A.2    Cooke, M.P.3    Levin, S.D.4    Qian, X.5    Perlmutter, R.M.6
  • 3
    • 0031594213 scopus 로고    scopus 로고
    • The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci
    • Ardouin, L., Ismaili, J., Malissen, B., and Malissen, M. (1998). The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci. J. Exp. Med. 187, 105-116.
    • (1998) J. Exp. Med. , vol.187 , pp. 105-116
    • Ardouin, L.1    Ismaili, J.2    Malissen, B.3    Malissen, M.4
  • 5
    • 0029874657 scopus 로고    scopus 로고
    • T cell antigen receptor signal transduction pathways
    • Cantrell, D. (1996). T cell antigen receptor signal transduction pathways. Annu. Rev. Immunol. 14, 259-274.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 259-274
    • Cantrell, D.1
  • 6
    • 0028783322 scopus 로고
    • Syk tyrosine kinase required for mouse viability and B-cell development
    • Cheng, A.M., Rowley, B., Pao, W., Hayday, A., Bolen, J.B., and Pawson, T. (1995). Syk tyrosine kinase required for mouse viability and B-cell development. Nature 378, 303-306.
    • (1995) Nature , vol.378 , pp. 303-306
    • Cheng, A.M.1    Rowley, B.2    Pao, W.3    Hayday, A.4    Bolen, J.B.5    Pawson, T.6
  • 7
    • 0030886836 scopus 로고    scopus 로고
    • The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling
    • Cheng, A.M., Negishi, I., Anderson, S., Chan, A., Bolen, J., Loh, D., and Pawson, T. (1997). The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. Proc. Natl. Acad. Sci. USA 94, 9797-9801.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9797-9801
    • Cheng, A.M.1    Negishi, I.2    Anderson, S.3    Chan, A.4    Bolen, J.5    Loh, D.6    Pawson, T.7
  • 8
    • 0031033292 scopus 로고    scopus 로고
    • Phosphotyrosine-dependent activation of Rac-1 GDP/ GTP exchange by the vav proto-oncogene product
    • Crespo, P., Schuebel, K.E., Ostrom, A.A., Gutkind, J.S., and Bustelo, X.R. (1997). Phosphotyrosine-dependent activation of Rac-1 GDP/ GTP exchange by the vav proto-oncogene product. Nature 385, 169-172.
    • (1997) Nature , vol.385 , pp. 169-172
    • Crespo, P.1    Schuebel, K.E.2    Ostrom, A.A.3    Gutkind, J.S.4    Bustelo, X.R.5
  • 9
    • 0030602798 scopus 로고    scopus 로고
    • The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte
    • Crompton, T., Gilmour, K.C., and Owen, M.J. (1996). The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte. Cell 86, 243-251.
    • (1996) Cell , vol.86 , pp. 243-251
    • Crompton, T.1    Gilmour, K.C.2    Owen, M.J.3
  • 10
    • 0030737886 scopus 로고    scopus 로고
    • Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production
    • da Silva, A.J., Li, Z., de Vera, C., Canto, E., Findell, P., and Rudd, C.E. (1997a). Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production. Proc. Natl. Acad. Sci. USA 94, 7493-7498.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 7493-7498
    • Silva, A.J.1    Li, Z.2    De Vera, C.3    Canto, E.4    Findell, P.5    Rudd, C.E.6
  • 11
    • 0030913178 scopus 로고    scopus 로고
    • TcR zeta/ CD3 signal transduction in T-cells: Downstream signaling via ZAP-70, SLP-76 and FYB
    • da Silva, A.J., Raab, M., Li, Z., and Rudd, C.E. (1997b). TcR zeta/ CD3 signal transduction in T-cells: downstream signaling via ZAP-70, SLP-76 and FYB. Biochem. Soc. Trans. 25, 361-366.
    • (1997) Biochem. Soc. Trans. , vol.25 , pp. 361-366
    • Silva, A.J.1    Raab, M.2    Li, Z.3    Rudd, C.E.4
  • 12
    • 0029065488 scopus 로고
    • Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T cells
    • Fehling, H.J., Krotkova, A., Saint-Ruf, C., and von Boehmer, H. (1995). Crucial role of the pre-T-cell receptor α gene in development of αβ but not γδ T cells. Nature 375, 795-798.
    • (1995) Nature , vol.375 , pp. 795-798
    • Fehling, H.J.1    Krotkova, A.2    Saint-Ruf, C.3    Von Boehmer, H.4
  • 13
    • 0030847208 scopus 로고    scopus 로고
    • Restoration of thymopoiesis in pTα-/-mice by anti-CD3∈ antibody treatment or with transgenes encoding activated LCK or tailless pTα
    • Fehling, H.J., Iritani, B.M., Krotkova, A., Forbush, K.A., Laplace, K., Perlmutter, R., and von Boehmer, H. (1997). Restoration of thymopoiesis in pTα-/-mice by anti-CD3∈ antibody treatment or with transgenes encoding activated LCK or tailless pTα. Immunity 6, 703-714.
    • (1997) Immunity , vol.6 , pp. 703-714
    • Fehling, H.J.1    Iritani, B.M.2    Krotkova, A.3    Forbush, K.A.4    Laplace, K.5    Perlmutter, R.6    Von Boehmer, H.7
  • 15
    • 0030869427 scopus 로고    scopus 로고
    • Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase C-γ, Grb2, and Vav after B cell antigen receptor activation
    • Fu, C., and Chan, A.C. (1997). Identification of two tyrosine phosphoproteins, pp70 and pp68, which interact with phospholipase C-γ, Grb2, and Vav after B cell antigen receptor activation. J. Biol. Chem. 272, 27362-27368.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27362-27368
    • Fu, C.1    Chan, A.C.2
  • 16
    • 0027153201 scopus 로고
    • - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • - triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol. 150, 4244-4253.
    • (1993) J. Immunol. , vol.150 , pp. 4244-4253
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 21
    • 0030849128 scopus 로고    scopus 로고
    • The role of Grb2-associated proteins in T-cell activation
    • Koretzky, G. (1997). The role of Grb2-associated proteins in T-cell activation, Immunol. Today 18, 401-406.
    • (1997) Immunol. Today , vol.18 , pp. 401-406
    • Koretzky, G.1
  • 22
    • 0027489782 scopus 로고
    • Restoration of early thymocyte differentiation in T-cell receptor β-chain-deficient mutant mice by transmembrane signaling through CD3e
    • Levelt, C.N., Mombaerts, P., Iglesias, A., Tonegawa, S., and Eichmann, K. (1993). Restoration of early thymocyte differentiation in T-cell receptor β-chain-deficient mutant mice by transmembrane signaling through CD3e. Proc. Natl. Acad. Sci. USA 90, 11401-11406.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11401-11406
    • Levelt, C.N.1    Mombaerts, P.2    Iglesias, A.3    Tonegawa, S.4    Eichmann, K.5
  • 23
    • 0029145881 scopus 로고
    • Regulation of thymocyte development through CD3: Functional dissociation between p56lck and CD3ζ in early thymic selection
    • Levelt, C.N., Mombaerts, P., Wang, B., Kohler, H., Tonegawa, S., Eichmann, K., and Terhorst, C. (1995). Regulation of thymocyte development through CD3:functional dissociation between p56lck and CD3ζ in early thymic selection. Immunity 3, 215-222.
    • (1995) Immunity , vol.3 , pp. 215-222
    • Levelt, C.N.1    Mombaerts, P.2    Wang, B.3    Kohler, H.4    Tonegawa, S.5    Eichmann, K.6    Terhorst, C.7
  • 30
    • 0028467163 scopus 로고
    • An activated form of lck transgene promotes thymic development in RAG-1 mutant mice
    • Mombaerts, P., Anderson, S.J., Perlmutter, R.M., Mak, T.W., and Tonegawa, S. (1994). An activated form of lck transgene promotes thymic development in RAG-1 mutant mice. Immunity 1, 261-268.
    • (1994) Immunity , vol.1 , pp. 261-268
    • Mombaerts, P.1    Anderson, S.J.2    Perlmutter, R.M.3    Mak, T.W.4    Tonegawa, S.5
  • 31
    • 0030002904 scopus 로고    scopus 로고
    • Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production
    • Motto, D.G., Ross, S.E., Wu, J., Hendricks-Taylor, L.R., and Koretzky, G.A. (1996). Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production. J. Exp. Med. 183, 1937-1943.
    • (1996) J. Exp. Med. , vol.183 , pp. 1937-1943
    • Motto, D.G.1    Ross, S.E.2    Wu, J.3    Hendricks-Taylor, L.R.4    Koretzky, G.A.5
  • 32
    • 0031571263 scopus 로고    scopus 로고
    • Three domains of SLP-76 are required for its optimal function in a T cell line
    • Musci, M.A., Motto, D.G., Ross, S.E., Fang, N., and Koretzky, G.A. (1997). Three domains of SLP-76 are required for its optimal function in a T cell line. J. Immunol. 159, 1639-1647.
    • (1997) J. Immunol. , vol.159 , pp. 1639-1647
    • Musci, M.A.1    Motto, D.G.2    Ross, S.E.3    Fang, N.4    Koretzky, G.A.5
  • 34
    • 0030906543 scopus 로고    scopus 로고
    • Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2
    • Raab, M., da Silva, A.J., Findell, P.R., and Rudd, C.E. (1997). Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2. Immunity 6, 155-164.
    • (1997) Immunity , vol.6 , pp. 155-164
    • Raab, M.1    Da Silva, A.J.2    Findell, P.R.3    Rudd, C.E.4
  • 36
    • 0028174201 scopus 로고
    • -/- mice in the absence of TCRb chain expression
    • -/- mice in the absence of TCRb chain expression. Int. Immunol. 6, 995-1001.
    • (1994) Int. Immunol. , vol.6 , pp. 995-1001
    • Shinkai, Y.1    Alt, F.2
  • 37
    • 0027406812 scopus 로고
    • Restoration of T cell development in RAG2-deficient mice by functional TCR transgenes
    • Shinkai, Y., Koyasu, S., Nakayama, K., Murphy, K.M., Loh, D.Y., Reinherz, E.L., and Alt, F.W. (1992a). Restoration of T cell development in RAG2-deficient mice by functional TCR transgenes. Science 259, 822-825.
    • (1992) Science , vol.259 , pp. 822-825
    • Shinkai, Y.1    Koyasu, S.2    Nakayama, K.3    Murphy, K.M.4    Loh, D.Y.5    Reinherz, E.L.6    Alt, F.W.7
  • 39
    • 0029962079 scopus 로고    scopus 로고
    • Early T lymphocyte progenitors
    • Shortman, K., and Wu, L. (1996). Early T lymphocyte progenitors. Annu. Rev. Immunol. 14, 29-47.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 29-47
    • Shortman, K.1    Wu, L.2
  • 40
    • 0026612411 scopus 로고
    • pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells
    • Stein, P.L., Lee, H.-M., Rich, S., and Soriano, P. (1992). pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell 70, 741-750.
    • (1992) Cell , vol.70 , pp. 741-750
    • Stein, P.L.1    Lee, H.-M.2    Rich, S.3    Soriano, P.4
  • 42
    • 0028042424 scopus 로고
    • FcR γ chain deletion results in pleiotrophic effector cell defects
    • Takai, T., Li, M., Sylvestre, D., Clynes, R., and Ravetch, J.V. (1994). FcR γ chain deletion results in pleiotrophic effector cell defects. Cell 76, 519-529.
    • (1994) Cell , vol.76 , pp. 519-529
    • Takai, T.1    Li, M.2    Sylvestre, D.3    Clynes, R.4    Ravetch, J.V.5
  • 44
    • 0029658306 scopus 로고    scopus 로고
    • p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells
    • Tuosto, L., Michel, F., and Acuto, O. (1996). p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells. J. Exp. Med. 184, 1161-1166.
    • (1996) J. Exp. Med. , vol.184 , pp. 1161-1166
    • Tuosto, L.1    Michel, F.2    Acuto, O.3
  • 46
    • 0030719389 scopus 로고    scopus 로고
    • A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes
    • Turner, M., Mee, P.J., Walters, A.E., Quinn, M.E., Mellor, A.L., Zamoyska, R., and Tybulewicz, V.L.J. (1997). A requirement for the Rho-family GTP exchange factor Vav in positive and negative selection of thymocytes. Immunity 7, 451-460.
    • (1997) Immunity , vol.7 , pp. 451-460
    • Turner, M.1    Mee, P.J.2    Walters, A.E.3    Quinn, M.E.4    Mellor, A.L.5    Zamoyska, R.6    Tybulewicz, V.L.J.7
  • 47
    • 0025780879 scopus 로고
    • Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
    • Tybulewicz, V.L., Crawford, C.E., Jackson, P.K., Bronson, R.T., and Mulligan, R.C. (1991). Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65, 1153-1163.
    • (1991) Cell , vol.65 , pp. 1153-1163
    • Tybulewicz, V.L.1    Crawford, C.E.2    Jackson, P.K.3    Bronson, R.T.4    Mulligan, R.C.5
  • 48
    • 0030293791 scopus 로고    scopus 로고
    • αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases
    • van Oers, N.S.C., Lowin-Kropf, B., Finlay, D., Connolly, K., and Weiss, A. (1996). αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity 5, 429-436.
    • (1996) Immunity , vol.5 , pp. 429-436
    • Van Oers, N.S.C.1    Lowin-Kropf, B.2    Finlay, D.3    Connolly, K.4    Weiss, A.5
  • 49
    • 0030963615 scopus 로고    scopus 로고
    • Structure and function of the pre-T cell receptor
    • von Boehmer, H., and Fehling, H.J. (1997). Structure and function of the pre-T cell receptor. Annu. Rev. Immunol. 15, 433-452.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 433-452
    • Von Boehmer, H.1    Fehling, H.J.2
  • 50
    • 0029004406 scopus 로고
    • T lymphocyte development in p56lck deficient mice: Allelic exclusion of the TcR beta locus is incomplete but thymocyte development is not restored by TcR beta or TcR alpha beta transgenes
    • Wallace, V.A., Kawai, K., Levelt, C.N., Kishihara, K., Molina, T., Timms, E., Pircher, H., Penninger, J., Ohashi, P.S., Eichmann, K., et al. (1995). T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR beta locus is incomplete but thymocyte development is not restored by TcR beta or TcR alpha beta transgenes. Eur. J. Immunol. 25, 1312-1318.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1312-1318
    • Wallace, V.A.1    Kawai, K.2    Levelt, C.N.3    Kishihara, K.4    Molina, T.5    Timms, E.6    Pircher, H.7    Penninger, J.8    Ohashi, P.S.9    Eichmann, K.10
  • 52
    • 0001584956 scopus 로고    scopus 로고
    • Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
    • Wu, J., Motto, D.G., Koretzky, G.A., and Weiss, A. (1996). Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity 4, 593-602.
    • (1996) Immunity , vol.4 , pp. 593-602
    • Wu, J.1    Motto, D.G.2    Koretzky, G.A.3    Weiss, A.4
  • 53
    • 0028915948 scopus 로고
    • Defective signaling through the T-and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
    • Zhang, R., Alt, F.W., Davidson, L., Orkin, S.H., and Swat, W. (1995). Defective signaling through the T-and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene. Nature 374, 470-473.
    • (1995) Nature , vol.374 , pp. 470-473
    • Zhang, R.1    Alt, F.W.2    Davidson, L.3    Orkin, S.H.4    Swat, W.5


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